A suture to be used in producing a medical instrument provided with a sutured site such as a stent graft, an artificial blood vessel or an artificial heart valve, has two components, i.e., a high melting-point component and a low-melting point component, the difference between the melting points of components being 30° C. or more and the low-melting point component is exposed on the suture surface entirely along the length direction. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the suture site is heated at such a temperature not allowing the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength and never becomes loose, can be formed.
A suture to be used in producing a medical instrument provided with a sutured site such as a stent graft, an artificial blood vessel or an artificial heart valve, has two components, i.e., a high melting-point component and a low-melting point component, the difference between the melting points of components being 30° C. or more and the low-melting point component is exposed on the suture surface entirely along the length direction. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the suture site is heated at such a temperature not allowing the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength and never becomes loose, can be formed.
A suture to be used in producing a medical instrument provided with a sutured site such as a stent graft, an artificial blood vessel or an artificial heart valve, has two components, i.e., a high melting-point component and a low-melting point component, the difference between the melting points of components being 30° C. or more and the low-melting point component is exposed on the suture surface entirely along the length direction. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the suture site is heated at such a temperature not allowing the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength and never becomes loose, can be formed.
A process for producing a water-insoluble shaped material, including a step of treating a raw material shaped material containing a water-soluble salt of a polyanionic polysaccharide with a treatment liquid containing an acid anhydride to insolubilize the raw material shaped material in water, and the process makes it possible to simply produce a water-insoluble shaped material in which intrinsic characteristics of the polyanionic polysaccharide being a raw material are retained, which has a high safety in that a chemical crosslinking agent is not required, and which is useful as a medical material, a food material, a cosmetic material, and the like.
A suture to be used in producing a medical instrument provided with a sutured part such as a stent graft, an artificial blood vessel or an artificial heart valve, namely, a suture for sewing a medical instrument. The suture comprises two components, i.e., a high-melting point component and a low-melting point component, the difference between the melting points of said components being 30oC or greater, and the low-melting point component is exposed on the suture surface entirely along the length direction. The suture is, for example, a multifilament yarn comprising a combination of a high-melting point component filament (3) with a low-melting point component filament (4) shown in Fig. 2, or a composite filament comprising the high-melting point component and the low-melting point component, or a yarn wherein the high-melting point component is coated with the low-melting point component. When a medical material formed of a fabric or a film is sutured or knotted with the suture and then the sutured site is heated at such a temperature as allowing not the high-melting point component but the low-melting point component alone to melt, the sutured site is fused and fixed. Thus, a knot or a seam, which sustains the fiber shape and strength of the suture and never becomes loose, can be formed.
A medical material for in vivo implantation use, characterized in that a polyethylene terephthalate ultrafine fiber is provided in at least a part of the medical material, wherein the polyethylene terephthalate ultrafine fiber is produced by spinning a polyethylene terephthalate chip, which is produced using germanium or titanium oxide as a catalyst, by a direct spinning method and then stretching the spun product and has a single fiber fineness of 0.8 dtex or less.
A61L 27/00 - Matériaux pour prothèses ou pour revêtement de prothèses
A61L 15/00 - Aspect chimique des bandages, des pansements ou des garnitures absorbantes ou utilisation de matériaux pour leur réalisation
A61L 17/00 - Matériaux pour suture chirurgicale ou pour ligature des vaisseaux sanguins
A61L 31/00 - Matériaux pour autres articles chirurgicaux
A61L 33/00 - Traitement antithrombogénique d'articles chirurgicaux, p. ex. de sutures, cathéters, prothèses ou d'articles pour la manipulation ou le conditionnement du sangMatériaux pour un tel traitement
D01F 6/62 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de produits d'homopolycondensation à partir de polyesters
7.
MEDICAL MATERIAL FOR IN VIVO IMPLANTATION CONTAINING SOFTENING AGENT AND/OR MOISTURIZING AGENT, METHOD FOR CONTROLLING CONTENT OF SOFTENING AGENT AND/OR MOISTURIZING AGENT IN THE MEDICAL MATERIAL, AND METHOD FOR PRODUCING THE MEDICAL MATERIAL FOR IN VIVO IMPLANTATION
Provided are a medical material for in vivo implantation which causes no retention of an exudate in the surroundings and yet shows a flexibility; a method for controlling the content of a softening agent and/or a moisturizing agent in the medical material; and a method for producing the medical material for in vivo implantation. When a hybrid medical material for in vivo implantation, which comprises a bioabsorbable material containing a softening agent and/or a moisturizing agent and a non-bioabsorbable porous base material, contains a large amount of the softening agent and/or moisturizing agent, retention of an exudate occurs in the surroundings of the medical material. It is found out that this phenomenon is a side effect of the softening agent and/or moisturizing agent. To prevent this side effect, a medical material for in vivo implantation in which the content of a softening agent and/or a moisturizing agent is controlled to less than 20 wt%; a method for controlling said content; and a method for producing the medical material for in vivo implantation are provided.
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