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2023
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Invention
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Biphenyl-substituted epithelial sodium channel blocking compounds. The present invention relates ... |
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Invention
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Bicyclic-substituted epithelial sodium channel blocking compounds. e.g.e.g., compounds of Formula... |
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2020
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Invention
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3,5-diamino-6-chloro-n-(n-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)c... |
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2019
|
Invention
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Aerosol delivery systems, compositions and methods.
An aerosol preparation assembly includes an ... |
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Invention
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3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds.
The p... |
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2018
|
Invention
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Sodium channel blockers.
The present invention relates to sodium channel blockers. The present i... |
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Invention
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Monothiol mucolytic agents. Provided are mucolytic agents represented by formula (Ia)-(Id):
6 ar... |
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Invention
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Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity.
This i... |
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Invention
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Delivering osmolytes by nasal cannula. The invention described herein is directed to method of tr... |
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Invention
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Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds. The present... |
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2017
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Invention
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Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry e... |
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Invention
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Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity. ... |
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Invention
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Sodium channel blockers for skin disorders.
Provided are methods of treating a variety of disord... |
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Invention
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3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds. The pre... |
|
|
Invention
|
Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity. This in... |
|
|
Invention
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3,5-diamino-6-chloro-n—(n-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)c... |
|
|
Invention
|
Arylalkyl-and aryloxyalkyl-substituted epithelial sodium channel blocking compounds. The present ... |
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|
Invention
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Stable sodium channel blockers. A very stable, selective and renally safe sodium channel blocker ... |
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2016
|
Invention
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Sodium channel blockers. The present invention relates to compounds of Formula (I) and pharmaceut... |
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Invention
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Inhaled hypertonic saline delivered by a heated nasal cannula. The invention described herein is ... |
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Invention
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Prodrugs of dithiol mucolytic agents. Provided are mucolytic compounds that are more effective, a... |
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Invention
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Novel prodrugs of dithiol mucolytic agents. Provided are mucolytic compounds that are more effect... |
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Invention
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Dithiol mucolytic agents. Provided are dithiol mucolytic agents. These agents increase the liquef... |
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Invention
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Sodium channel blockers for skin disorders. Provided are methods of treating a variety of disorde... |
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Invention
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Novel monothiol mucolytic agents. Provided are mucolytic agents represented by formula (la)-(ld) ... |
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2015
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Invention
|
Stable sodium channel blockers.
A very stable, selective and renally safe sodium channel blocker... |
|
|
Invention
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3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl)pyrazine-2-carboxamide compounds. The pres... |
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2014
|
Invention
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Arylalkyl- and aryloxyalkyl-substituted epthelial sodium channel blocking compounds. The present ... |
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Invention
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Methods of treatment. Embodiments disclosed herein are directed to methods, compositions and appa... |
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2013
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Invention
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3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds. The pr... |
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Invention
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Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insuffic... |
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Invention
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Novel mucolytic agents.
Provided is a method of liquefying mucus from mucosal surfaces by admini... |
