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2025
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Invention
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Detection of modified nucleobases in dna samples.
Described are methods of detecting modified nu... |
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Invention
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Nanopore voltage methods.
A method for sequencing a nucleic acid molecule includes providing a s... |
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Invention
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Systems and methods for training a machine learning model using fragmentomic features and applica... |
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Invention
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Assay for detection of mutations conferring resistance to treatment with an immunotherapeutic age... |
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Invention
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Intermolecular consensus of partially read sequences. A computer-implemented method for identifyi... |
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Invention
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Detergent-free nanopore delivery. The disclosure relates to nanopore preparations with reduced co... |
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Invention
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Systems and methods for somatic small variant calling. The variant caller algorithms described he... |
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Invention
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Systems and methods for variant calling. The variant caller algorithms described herein can be us... |
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Invention
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Primer extension target enrichment and improvements thereto including simultaneous enrichment of ... |
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Invention
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Multiplexing analog components in biochemical sensor arrays.
Techniques for increasing the densi... |
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Invention
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In vitro amplification of dna methylation patterns. The present disclosure provides methods of am... |
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Invention
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High throughput inramolecular consensus reads. Described herein are methods, systems, and apparat... |
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Invention
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Single molecule multi-molecular trace methods and systems.
Methods of sequencing by expansion an... |
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Invention
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Tagged nucleoside compounds useful for nanopore detection.
The disclosure relates to tagged nucl... |
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Invention
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Systems and methods for minimum residual disease (mrd) detection. The disclosure is related to us... |
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Invention
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Target enrichment by unidirectional dual probe primer extension.
The present disclosure provides... |
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Invention
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Techniques for synthesizing a macromolecule from a sample. An aspect of the present disclosure re... |
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Invention
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Nanopore-based sequencing with varying voltage stimulus.
A method of analyzing a molecule is dis... |
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Invention
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Machine learning model compression for digital pathology analysis. Techniques for compressing mac... |
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Invention
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Sensor circuit for controlling, detecting, and measuring a molecular complex.
A device for contr... |
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Invention
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Detecting cancer driver genes and pathways.
Described herein are methods, systems, and apparatus... |
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Invention
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Removing and reinserting protein nanopores in a membrane using osmotic imbalance.
Techniques for... |
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Invention
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Compositions of modified nucleoside triphosphates. The invention relates to a diastereomer of nuc... |
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2024
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Invention
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Methods and compositions for nucleic acid library and template preparation for duplexed sequencin... |
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Invention
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Enhancement of nucleic acid polymerization by aromatic compounds. in vitroin vitro primer extensi... |
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Invention
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Normalization and baseline shift removal by rotation in added data dimensions.
A method of using... |
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Invention
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Modular quality management systems and methods. A system for quality control of a medical device ... |
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Invention
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Phased nanopore array.
Techniques described herein can apply AC signals with different phases to... |
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Invention
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Electrical enhancement of bilayer formation.
A method of forming a plurality of lipid bilayers o... |
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Invention
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Systems and methods for endpoint genotyping. The present disclosure relates to performing endpoin... |
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Invention
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Systems and methods for classifiying unknown samples into known genotypes. The present disclosure... |
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Invention
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Systems and methods for determining crosstalk coefficients. The present disclosure relates to det... |
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Invention
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Memory-efficient data format and utilization for parallel processing. A method for efficiently pr... |
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Invention
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Systems for forming a nanopore in a lipid bilayer.
A method of forming a nanopore in a lipid bil... |
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Invention
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Dpo4 polymerase variants with improved properties. Recombinant DPO4-type DNA polymerase variants ... |
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Invention
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Amplification-free target enrichment workflow for direct detection of nucleic acid modifications.... |
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Invention
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Collaboration platform for analyzing large privacy-impacted datasets. A collaboration platform is... |
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Invention
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Single molecule nucleic acid detection by mismatch cleavage.
Methods and materials are provided ... |
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Invention
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Systems, system components and methods for automated macromolecule synthesis. A coupling assembly... |
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Invention
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Systems, system components and methods for automated macromolecule synthesis. A system and method... |
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Invention
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Systems, system components and methods for automated macromolecule synthesis. A flow cell is prov... |
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Invention
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Synthesis of isomerically pure polyol-based phosphoramidites.
The present disclosure relates to ... |
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Invention
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Dpo4 polymerase variants.
Recombinant DPO4-type DNA polymerase variants with amino acid substitu... |
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Invention
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Nanopore arrays. A method of analyzing molecules using a nanopore array including a plurality of ... |
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Invention
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High throughput nucleic acid sequencing by expansion.
Nucleic acid sequencing methods and relate... |
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2023
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Invention
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Compositions and methods that reduce prussian blue formation during nanopore sequencing.
This ap... |
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2022
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Invention
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Engineered nanopore with a negatively charged polymer threaded through the channel.
Nanopores ha... |
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Invention
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Hybridization buffer formulations.
The present disclosure is directed to hybridization buffers, ... |
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Invention
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Methods for base-level detection of methylation in nucleic acids.
The invention includes improve... |
