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2024
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Invention
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Bispecific chimeric antigen receptors and therapeutic uses thereof.
The invention is directed to... |
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Invention
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Vivo gene therapy using intraosseous delivery of a lentiviralgene construct.
Methods, compositio... |
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Invention
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A4b1 binding aptamers.
Various implementations described herein relate to oligonucleotides that ... |
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Invention
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Modified vectors. This disclosure relates generally to viral vectors useful for gene therapy appl... |
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Invention
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A multi-stage vaccine antigen for malaria. The present disclosure provides a recombinant antigen ... |
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Invention
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Asymmetric circular tandem repeat proteins. In certain embodiments, the present invention provide... |
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Invention
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Systems and methods to provide therapeutic factor viii using ultrasound-mediated nucleic acid del... |
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Invention
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Mutant interleukin 15 expressing immune cells. The present disclosure provides methods and artifi... |
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Invention
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Inducible programmed cell death-1 (pd1)-cytokine chimera for potentiated immune cell function. Ar... |
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Invention
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Therapeutic methods. The invention provides methods for treating a disease associated with SRC Fa... |
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Invention
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Proteomic screening for lysosomal storage diseases.
Early detection of lysosomal storage disease... |
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Invention
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Intein-mediated reconstitution of voltage-gated sodium channel function. Artificial expression co... |
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Invention
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Inducible cytokine transgenes for potentiated immune cell function. Artificial expression constru... |
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Invention
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Cd62l (l-selectin) aptamer and its application for t cell isolation. Various implementations desc... |
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2023
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Invention
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N-myristoyltransferase inhibitors and methods of use. Provided herein are compounds of Formula (I... |
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Invention
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Cerebral near infrared spectroscopy probe in infants and preterm neonates. An example method incl... |
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Invention
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Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell ... |
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Invention
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Melanocortin and glp-1 receptor agonists and methods of use. |
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Invention
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Endotracheal tube having partial wire reinforcement.
An endotracheal tube having a bendable port... |
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Invention
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Synthetic intermediates for universal chimeric antigen receptor immune cell therapies. Example co... |
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Invention
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Variants of coagulation factor viii and uses thereof. Variants of coagulation factor VIII (FVIII)... |
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Invention
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Processing images to associate with stages of a surgical procedure.
A method includes accessing ... |
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Invention
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Oxytocin derivatives and methods of use. Provided herein are compounds of formula (I). In certain... |
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Invention
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Homology directed repair compositions for the treatment of hemoglobinopathies.
The present discl... |
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Invention
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Recombinant receptors binding b cell activation factor receptor and uses thereof. Recombinant rec... |
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Invention
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Inhibiting mast cell activation by binding sialic acid-binding immunoglobulin-like lectin-9 (sigl... |
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Invention
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Ventilation system. A system includes a container configured to contain a liquid. The system also... |
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Invention
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Recombinant proteins that stimulate an immune response in the presence of naturally inhibitory li... |
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Invention
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Simplified method of preparing cells for patient administration. The current disclosure describes... |
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2022
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Invention
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Methods and systems to functionally ablate 3 prime rna ends. Methods and systems to functionally ... |
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Invention
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Methods and compositions for modulating the activity of a dimerizing agent regulated immunomodula... |
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Invention
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Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof.
Hematopoietic... |
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Invention
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Sensor paper and methods for use. A sensor paper is infused with bromothymol blue (BTB), a water-... |
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Invention
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Compositions incorporating a genetically attenuated plasmodium with modified liver stage nuclear ... |
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Invention
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T-cell manufacturing methods.
T cell manufacturing methods that co-culture T cells with autologo... |
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Invention
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Synthetic nucleic acid elements for enhancing car t cell efficacy.
Some embodiments of the metho... |
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Invention
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Gene editing for expression of functional factor viii for the treatment of hemophilia.
Gene-edit... |
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Invention
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Engineering peptides for a a vb6 integrin binding and related methods of use and synthesis.
Embo... |
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Invention
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Systems and methods for clearing indwelling catheters.
Systems, devices, and methods for clearin... |
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Invention
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Activity-inducible fusion proteins having a heat shock protein 90 binding domain.
Activity-induc... |
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Invention
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Hybrid and truncated immune cell proteins.
In Hybrid and truncated immune cell proteins are desc... |
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2021
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Invention
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Immunomodulatory clinical biomarker profiles and uses thereof.
The present disclosure relates to... |
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Invention
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Diagnostic methods for kawasaki disease.
Compositions and methods are provided for diagnosis, pr... |
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Invention
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Compositions and methods for targeting plasmodium male gamete protein to block malaria parasite t... |
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Invention
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Single-domain antibodies that bind sars-cov-2.
Single-domain antibodies that bind the severe acu... |
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Invention
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Compositions and methods to reduce neuroinflammation.
The use of inhibitors upstream of mTOR in ... |
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Invention
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Devices, systems, and methods for automated dissection and processing of biological samples.
Sys... |
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Invention
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Chimeric antigen receptors (cars) targeting natural killer cells.
The current disclosure provide... |
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Invention
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Antibodies that specifically bind peptides associated with the primary immunodeficiencies: wiskot... |
