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2025
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Invention
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Small molecule cereblon binders that induce the degradation of proteins (kdm4b, vcl) relevant to ... |
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Invention
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Biologically active ganoderma lucidum compounds and synthesis of anticancer derivatives; ergoster... |
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Invention
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Small-molecule modulators of lymphocyte-specific protein tyrosine kinase and casein kinase 1a. Th... |
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2024
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Invention
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Chemical matters for targeting histone acetyltransferase p300 (ep300) and creb-binding protein (c... |
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Invention
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Treatment of low-grade glioma with mirdametinib.
The present disclosure relates to a method of t... |
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Invention
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Kmt2a::aff1 neoantigen and use thereof in adoptive immunotherapy. KMT2A: :AFF1KMT2A: :AFF1 fusion... |
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Invention
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Disruption of ets1 and rbpj in t cells to enhance immunotherapy. The application provides modifie... |
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Invention
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Chimeric antigen receptors targeting leucine rich repeat containing 15 (lrrc15). The application ... |
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Invention
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Reverse genetics vector and associated method of use. A modified pHW2000 vector comprising an ina... |
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Invention
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Method for treating sickle cell disease by targeting senescent cells. Disclosed are methods for t... |
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Invention
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Epigenetic signature of t cell aging and malignancy. A 139-gene epigenetic signature for use in. ... |
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Invention
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A sequence selective dna binding molecule (syngrader). The present disclosure relates to chemical... |
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Invention
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Modified aav p5 promoter for improved vector titer and purity. A recombinant AAV vector including... |
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Invention
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Methods of treating disorders associated with castor.
The present disclosure relates to methods ... |
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Invention
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Chimeric receptors. The application relates to chimeric receptors, particularly chimeric receptor... |
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Invention
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Use of prime editing for treating sickle cell disease. The present disclosure provides methods fo... |
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Invention
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Use of glutamine for the treatment of cancer and for enhancing the efficacy of an immunotherapy. ... |
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2023
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Invention
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Compositions and methods for self-adjuvanting aav vaccines. A self-adj uvating recombinant, non-r... |
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Invention
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Small molecule modulators of pantothenate kinases.
The present disclosure relates to chemical co... |
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Invention
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Compositions and methods for prevention and treatment of hearing loss.
Methods and compositions ... |
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Invention
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Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious di... |
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Invention
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Methods for improved risk stratification of adult and pediatric acute myeloid leukemia patients u... |
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Invention
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Nlrp12 and nlrc5 modulators and methods for using the same to modulate diseases. Disclosed are co... |
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Invention
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Method for nucleic acid amplification.
Provided herein are compositions and methods for accurate... |
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Invention
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Disruption of asxl1 in t cells to enhance immunotherapy. The application relates to modified immu... |
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Invention
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Substituted n-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)arylsulfonamide analogs as mo... |
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Invention
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Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione/2-(2,6-dioxopiperidin-3-yl)isoindoline-1... |
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Invention
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Disruption of kdm4a in t cells to enhance immunotherapy.
The application provides modified immun... |
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Invention
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T cell regulation.
Regulatory T cells (Treg) limit autoimmunity but can also attenuate the magni... |
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Invention
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Synergistic antifungal composition and method.
This invention provides a method for inhibiting t... |
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Invention
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Methods for expanding immune cells.
The present invention relates to a chimeric receptor capable... |
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Invention
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Method for preparing t cells for adoptive t cell therapy.
Disclosed is a method for preparing T ... |
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Invention
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Method for improving auditory perception using a vipr1 inhibitor.
Methods for increasing auditor... |
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Invention
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Bispecific chimeric antigen receptors targeting grp78 and cd123 or grp78 and b7h3.
The applicati... |
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2022
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Invention
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Chimeric antigen receptors comprising a pdz binding motif.
The present application provides chim... |
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Invention
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Kit and method for analyzing t cell receptors from single t cells.
A kit and method for analyzin... |
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Invention
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Compositions and methods comprising substituted n-(2-chloro-6-methylphenyl)-2-((6-(6-membered het... |
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Invention
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Substituted 2-(2-(2,6-dioxopiperidin-3-yl)-1- oxoisoindolin-5-yl) acetamide analogs as modulators... |
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Invention
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Pre-effector car-t cell gene signatures.
The present disclosure relates generally to methods for... |
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Invention
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Systems and methods for cell-type identification.
An exemplary embodiment of the present disclos... |
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Invention
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Substituted n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)methyl)benzamide analogs as modu... |
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Invention
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Pharmacogenomics score to make decisions on therapy augmentation in aml.
The disclosure relates ... |
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Invention
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Methods to determine cd4+ memory t cell responses to sars-cov-2 infection or vaccination.
Disclo... |
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Invention
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Method for preserving developmental potential of immune cells used for adoptive cellular therapie... |
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Invention
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Methods and compositions for transduction of nk cells.
Disclosed are methods for transducing cel... |
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Invention
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Interferons and nuclear export inhibitors for use in methods of treating cancer.
Methods for ind... |
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Invention
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Systems and methods for base editing of hbg1/2 gene promoter and fetal hemoglobin induction.
Sys... |
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2021
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Invention
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Chimeric antigen receptors targeting splice variants of the extracellular matrix proteins tenasci... |
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Invention
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Substituted 4-(3-aminoprop-1-yl)aminoquinoline analogs as modulators of melanoma-associated antig... |
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1999
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P/S
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EDUCATIONAL SERVICES, NAMELY, CONDUCTING SEMINARS, LECTURES, MEETINGS, ROUNDS AND SYMPOSIUMS IN T... |
