The United States of America as represented by the Secretary of the Department of Health and Human Services

États‑Unis d’Amérique

 
Quantité totale PI 185
Rang # Quantité totale PI 6 986
Note d'activité PI 2,1/5.0    18
Rang # Activité PI 46 258

Brevets

Marques

160 0
0 0
25 0
0
 
Dernier brevet 2024 - Nanoparticle-derived vaccines ag...
Premier brevet 1979 - Method and apparatus for travers...

Derniers inventions, produits et services

2023 Invention Nanoparticle-derived vaccines against poxviruses, and methods for making and using the same. The ...
2022 Invention Polymeric nanoparticles comprising a histone deacetylase 6 / phosphoinositide 3-kinase-8 dual inh...
2021 Invention Differentiation of trophectoderm lineage cells from pluripotent stem cells. Methods for generatin...
Invention Corona virus binders. The present invention relates to the field of virology, more specifically t...
2020 Invention Methods of modulating immune responses with cationic lipid vaccine compositions. The present disc...
Invention Epstein-barr virus vaccines. Vaccines are provided that elicit neutralizing antibodies to Epstein...
Invention Nociceptor differentiation from human pluripotent stem cells. Methods for generating neural crest...
2019 Invention Anti-dengue virus ns1 protein monoclonal antibodies. The present invention provides matched antib...
Invention Compositions and methods for treating beta-globinopathies. The present invention provides new com...
Invention New compositions and methods for treating beta-globinopathies. The present invention provides new...
Invention Compositions and methods for cell culture. Compositions and methods useful for culturing mammalia...
Invention New compositions and detection methods for onchocerca volvulus infection. Onchocerca volvulus (Ov...
Invention Use of epithelial membrane protein 2 [emp2] targeting agents in treating lung disorders. Disclose...
Invention Rickettsiaceae detection. Primers, probes and kits for detection of Rickettsiaceaeare provided. A...
Invention Detecting protein interaction sites in nucleic acids. Compositions and methods useful for identif...
2018 Invention Multi-focal structured illumination microscopy systems and methods. A multi-focal structured illu...
Invention Compositions, methods and uses for dengue virus serotype-4 constructs. Embodiments herein report ...
Invention Compositions and methods for blocking transmission of plasmodium. Plasmodium P47 D2 polypeptides,...
2017 Invention Il-15/il-15 receptor alpha treatment regimens and use with therapeutic vaccines. The invention pr...
Invention Heterodimers of il-15 and il-15r alpha to increase thymic output and to treat lymphopenia. The pr...
Invention Use of heterodimeric il-15 in adoptive cell transfer. The disclosure provides methods of performi...
Invention Extracellular vesicles, methods of making them, and methods of reducing liver uptake of extracell...
Invention Anti-py1235-met immunological binding reagent. Methods and compositions are described herein for ...
2016 Invention Detection of live attenuated influenza vaccine viruses. Primers, probes and kits for detection of...
Invention Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross...
Invention A method of detecting molecules in proximity to a target molecule in a sample. Antibody-based met...
Invention Use of delta tocopherol for the treatment of lysosomal storage disorders. This disclosure relates...
Invention Enhancing astrocyte neuroprotective functions using p53 isoforms. The present invention is direct...
Invention Legionella nucleic acids in a sample. Legionella, and kits that contain the disclosed probes and/...
Invention Lutzomyia longipalpis polypeptides and methods of use. Leishishmaniasis are disclosed.
Invention Multiplexed spectral lifetime detection of phosphors. New methods and assays for multiplexed dete...
Invention Extension of replicative lifespan in diseases of premature aging using p53 isoforms. The present ...
Invention Methods and compositions for inducing an immune response using conserved element constructs. The ...
Invention Anti-cd133 monoclonal antibodies and related compositions and methods. Anti-CD133 monoclonal anti...
Invention Human monoclonal antibodies specific for cd22. d) of 25 nM or less. Nucleic acids encoding these ...
Invention Humanized monoclonal antibodies that specifically bind and/or neutralize japanese encephalitis vi...
2015 Invention Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer. The present disc...
Invention Influenza virus recombinant proteins. The present invention includes influenza Hemagglutinin prot...
Invention Postnatal stem cells and uses thereof. The invention generally relates to postnatal dental stem c...
Invention Identification of antibodies specific for at least two different lyssaviruses. Described herein i...
Invention Lutzomyia longipalpis polypeptides and methods of use. Lu. longipalpis polynucleotides are also d...
Invention Membrane proximal region of hiv gp41 anchored to the lipid layer of a virus-like particle vaccine...
Invention Use of nitrite salts for the treatment of cardiovascular conditions. It has been surprisingly dis...
2014 Invention Replication-competent adenoviral vectors. This invention provides improved replication-competent ...
2013 Invention Pathogenic phlebovirus isolates and compositions and methods of use. Phleboviruses and their use ...
Invention Real-time pcr for the detection of pathogens. Neisseria meningitidis in a sample.