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2024
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Invention
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Acyl sulfonamides that are bcl family antagonists for use in clinical management of conditions ca... |
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Invention
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Methods of treating retinal vasculopathies.
The present invention relates to methods of treating... |
|
|
Invention
|
Methods of treating age-related macular degeneration. The invention relates to methods of treatin... |
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|
Invention
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Antibodies directed to tie-2 and methods of use.
The invention relates to anti-Tie2 antibodies a... |
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2023
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Invention
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Klotho polypeptide or polynucleotide for improving cognition. Methods of improving cognitive func... |
|
|
Invention
|
Treatment of a senescence-associated ocular disease or disorder using a bcl-xl selective inhibito... |
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Invention
|
Antibodies directed to tie-2 and vegf and methods of use.
The invention relates to specific cons... |
|
|
Invention
|
Antibodies directed to tie-2 and vegf and methods of use. The invention relates to specific const... |
|
2022
|
Invention
|
Methods of treating retinal vasculopathies.
The invention relates to methods of treating certain... |
|
|
Invention
|
Methods of treating retinal vasculopathies. The invention relates to methods of treating certain ... |
|
|
Invention
|
Methods of treating retinal vasculopathies. The present invention relates to methods of treating ... |
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2021
|
Invention
|
Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes ... |
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Invention
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Methods of inhibiting pathological angiogenesis. This invention is based on the discovery that ma... |
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Invention
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Cancer treatment by senescence induction followed by a senolytic. This invention is based on meth... |
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2020
|
Invention
|
Treating cardiovascular disease by selectively eliminating senescent cells. Methods are provided ... |
|
|
Invention
|
Treating liver disease by selectively eliminating senescent cells. Methods are provided herein fo... |
|
|
Invention
|
Antibodies directed to tie-2 and methods of use. The invention relates to anti-Tie2 antibodies an... |
|
|
Invention
|
Crystalline solid meglumine salt inhibitor of bcl and methods of making and using same.
Provided... |
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|
Invention
|
Crystalline solid meglumine salt inhibitor of bcl and methods of making and using same. Provided ... |
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Invention
|
Combination treatment for senescence-associated diseases. The present invention provides for the ... |
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Invention
|
Mcl-1 inhibitor macrocycle compounds for use in clinical management of conditions caused or media... |
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Invention
|
Treating cognitive decline and other neurodegenerative conditions by selectively removing senesce... |
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|
Invention
|
Phospholidines that are bcl family antagonists for use in clinical management of conditions cause... |
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Invention
|
Phosphonamidates that are bcl family antagonists for use in clinical management of conditions cau... |
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|
Invention
|
Method of treating the osteoarthritic joint. Disclosed herein are methods of treating a patient d... |
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|
Invention
|
Use of a heterocyclic bcl-2 inhibitor for removing senescent cells and treating senescence-associ... |
|
|
Invention
|
Use of a heterocyclic bcl-xl inhibitor and related analogs for removing senescent cells in the tr... |
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2019
|
Invention
|
Composition comprising a gene vector that selectively depletes p16 positive senescent cells.
Pol... |
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Invention
|
Killing senescent cells and treating senescence-associated conditions using a bcl inhibitor and a... |
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|
Invention
|
Killing senescent cells and treating senescence-associated conditions using a bel inhibitor and a... |
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|
Invention
|
Chemical entities that kill senescent cells for use in treating age-related disease.
Disclosed h... |
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|
Invention
|
Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for t... |
|
|
Invention
|
Therapy for removing senescent cells and treating senescence-associated disease using an mdm2 inh... |
|
|
Invention
|
Composition comprising a gene vector that selectively depletes p16 positive senescent cells. Poly... |
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|
Invention
|
Acyl phosphonamidates and acyl benzylamines that are bcl family antagonists for use in clinical m... |
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|
Invention
|
Products of chiral synthesis of cis-imidazoline compounds and their use.
This invention provides... |
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|
Invention
|
Autologous mitochondrial extraction and expansion. This invention creates a new paradigm for the ... |
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2018
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Invention
|
Inhibitors of hsp90, pi3-kinase, proteasome, hdac, and p97 pathways for selective removal of sene... |
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|
Invention
|
Treatment of lung diseases using pharmaceutical agents that eliminate senescent cells.
This inve... |
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P/S
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Pharmaceutical preparations for the treatment of diseases, disorders, and conditions associated w... |
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P/S
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Pharmaceutical preparations for treatment of diseases, disorders, and conditions associated with ... |
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|
P/S
|
Pharmaceutical compositions for treatment and prophylaxis of
diseases, disorders, and conditions... |
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2016
|
Invention
|
Acylsulfonamide derivatives for treating senescence-associated diseases and disorders. Compounds ... |
|
2015
|
P/S
|
Pharmaceutical compositions for treatment and prophylaxis of diseases, disorders, and conditions ... |
