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2025
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Invention
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Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators.
The invention is ... |
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Invention
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Preparation method of a bruton's tyrosine kinase degrader thereof. Provided herein are methods of... |
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Invention
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Compounds for the degradation of egfr kinase.
Disclosed herein are novel bifunctional compounds ... |
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Invention
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Solid forms comprising a bruton's tyrosine kinase degrader and uses therefor. Provided herein are... |
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Invention
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Targeted pyrrolobenzodiazapine conjugates. Provided (Ia) are conjugator-functionalized pyrroloben... |
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Invention
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Kat6 inhibitors. Disclosed herein are compounds used as inhibitors of KAT6 and pharmaceutical com... |
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Invention
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Macrocyclic compounds as ras inhibitors. The present invention provides macrocyclic compounds, th... |
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Invention
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Gamma delta t cell compositions and methods of use. The present disclosure provides genetically m... |
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Invention
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Heterocyclic compounds, compositions thereof, and methods of treatment therewith. Provided herein... |
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Invention
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Treating b-cell proliferative disorder with chimeric degradation activating compound. A method of... |
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P/S
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Providing secure online web messaging and telecommunications services, namely, electronic transmi... |
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2024
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Invention
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Degradation of irak4 by conjugation of irak4 inhibitors with e3 ligase ligands and methods of use... |
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Invention
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Anti-pd1 antibodies and their use as therapeutics and diagnostics.
Provided are antibodies that ... |
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Invention
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Anti-pd-1-based treatment before and after surgery. The disclosure relates to treatment of solid ... |
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Invention
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Solid forms comprising a b-raf kinase dimer inhibitor, methods of preparation, and uses therefor.... |
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Invention
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Ionizable lipids and lipid nanoparticles for rna delivery. Provided herein is novel ionizable cat... |
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Invention
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Stable high concentration arginine formulations containing pd-1 antibody and methods of use there... |
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Invention
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Substituted 6-(pyrimidin-4-yl)quinoline compounds as cyclin dependent kinase inhibitors. This dis... |
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Invention
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1-(1-oxo-1,2-dihydrophthalazin-6-yl)cycloalkyl-1-carboxamide derivatives as mta-cooperative inhib... |
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Invention
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Kat6 inhibitors. Disclosed herein are compounds used as inhibitors of KAT6, or a pharmaceutically... |
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Invention
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4-((5-(3-(4-(pyridin-2-yl)cyclopentyl)-1 h-pyrazol-3-yl)amino)-benzenesulfonamide derivatives and... |
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P/S
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Pharmaceutical preparations for the treatment and prevention of cancer, autoimmune and inflammato... |
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Invention
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Circular rna and preparation methods thereof. Compositions and methods for efficiently constructi... |
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Invention
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Immune-related gene expression signatures and methods relating thereto. Among other things, the p... |
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Invention
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Bicyclic compounds as cdk inhibitors. Disclosed herein are bicyclic compound derivatives used as ... |
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Invention
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Treatment of esophageal cancer with anti-lag3, anti-pd-1 and chemotherapy. Described herein are m... |
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Invention
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Treatment of lung cancer with anti-pd-1 and chemotherapy. Provided is a treatment of lung cancer ... |
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Invention
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Bioactive conjugates, preparation method and use thereof. Provided herein are compounds comprisin... |
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Invention
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Quinoline derivatives and pharmarceutical compositions thereof for the treatment of disease. Disc... |
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Invention
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Bioactive conjugates, preparation method and use thereof. Compounds of formula (I) are provided, ... |
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Invention
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Bioactive conjugates, preparation method and use thereof. Compounds of formula (Ia) are provided,... |
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Invention
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Antibody drug conjugates.
Antibody-drug conjugate compounds comprising a linker and methods of u... |
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Invention
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Solid forms of a tyk2 inhibitor, method of preparation, and use thereof.
Disclosed herein are a ... |
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Invention
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Benzofuran derivatives as sik inhibitors and use thereof. Provided are compounds of formula (I) a... |
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Invention
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Compounds for the degradation of egfr kinase. Disclosed herein are novel bifunctional compounds f... |
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Invention
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Methods of cancer treatment using anti-ox40 antibodies in combination with anti-pd1 antibodies. P... |
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Invention
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Isoquinolinone derivatives and 4h-quinolizinone derivatives and pharmarceutical compositions ther... |
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Invention
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Targeted pyrrolobenzodiazapine conjugates. Provided are compounds comprising pyrrolobenzodiazepin... |
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Invention
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Anti-cldn6 antibodies and methods of use.
The present disclosure provides for antibodies and ant... |
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Invention
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5-amino-6, 8-dihydro-1h-furo [3, 4-d] pyrrolo [3, 2-b] pyridine-2-carboxamide derivatives as mta-... |
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Invention
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Bioactive conjugate, preparation method therefor and use thereof. The present disclosure provides... |
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Invention
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Anti-cldn6 and anti-cd3 multispecific antibodies and methods of use. The present disclosure provi... |
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Invention
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Anti-cd3 multispecific antibodies and methods of use. The present disclosure provides for antibod... |
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Invention
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Anti-cldn6 antibodies and methods of use. The present disclosure provides for antibodies and anti... |
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Invention
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Muc1 and cd16a antibodies and methods of use. The present disclosure provides for multi-specific ... |
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Invention
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Cd16a antibodies and methods of use. The present disclosure provides antibodies and antigen-bindi... |
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Invention
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Muc1 antibodies and methods of use. The present disclosure provides for antibodies and antigen-bi... |
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Invention
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Preparation methods for a highly concentrated pd1 antibody solution by applying single-pass tange... |
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2022
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P/S
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Medicines for human purposes, Cachets for pharmaceutical purposes, Capsules for medicines, pharma... |
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2018
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P/S
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Pharmaceutical preparations for the prevention and treatment of the central nervous system, namel... |
