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2025
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Invention
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Amatoxin antibody-drug conjugates and uses thereof.
Amatoxins, as well as antibody-drug conjugat... |
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Invention
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Targeted amatoxin conjugate for the treatment of solid tumors.
An amatoxin-linker construct cont... |
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Invention
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B-lymphocyte specific amatoxin antibody conjugates.
A conjugate contains an amatoxin, a target-b... |
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Invention
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Synthesis of (s)-6-hydroxytryptophan and derivatives thereof.
Novel methods and compounds synthe... |
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2024
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Invention
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Modular linker compound for target-binding drug conjugates.
The present disclosure relates to mo... |
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Invention
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New antibody-drug conjugate as well as methods of production and uses thereof.
The present discl... |
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Invention
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Modular linker compound for target-binding drug conjugates. The present invention relates to modu... |
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Invention
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Antibody-drug conjugate comprising an anti-gucy2c antibody as well as methods of production and u... |
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Invention
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Novel nicotinamide phosphoribosyltransferase inhibitors and uses thereof.
The present disclosure... |
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Invention
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Novel nicotinamide phosphoribosyltransferase inhibitors and uses thereof. The present disclosure ... |
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Invention
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B-lymphocyte specific amatoxin antibody conjugates.
The present application relates to conjugate... |
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Invention
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Compositions and methods for the depletion of cd5+ cells.
The invention provides anti-CD5 antibo... |
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P/S
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Pharmaceutical preparations for the treatment of cancer; Pharmaceuticals for the treatment of can... |
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Invention
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Composition comprising a combination of immune checkpoint inhibitor and antibody-amatoxin conjuga... |
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Invention
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Subcutaneously administered antibody-drug conjugates for use in cancer treatment.
The present ap... |
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Invention
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Subcutaneously administered antibody-drug conjugates for use in cancer treatment |
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Invention
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Subcutaneously administered antibody-drug conjugates for use in cancer treatment. The present app... |
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2023
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Invention
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Anti-gucy2c antibody and uses thereof.
In a first aspect the present application pertains to an ... |
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Invention
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Anti-gucy2c antibody and uses thereof |
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Invention
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Anti-gucy2c antibody and uses thereof. In a first aspect the present application pertains to an a... |
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Invention
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Methods of improving the therapeutic index.
The present invention pertains to treatment regimens... |
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Invention
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Methods of improving the therapeutic index of amatoxin-antibody conjugates. The present invention... |
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Invention
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Amanitin conjugates. The invention relates to a conjugate comprising (a) an amatoxin comprising (... |
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2022
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Invention
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Method of treating cancer using amanitin derivatives. The invention relates to methods for synthe... |
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Invention
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B-lymphocyte specific amatoxin antibody conjugates. The present application relates to conjugates... |
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2021
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Invention
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Amatoxin analogs and uses thereof.
This application relates to amatoxin analogs in which the... |
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Invention
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Amatoxin analogs and uses thereof. This application relates to amatoxin analogs in which the tran... |
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Invention
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T-cell depleting therapies.
Provided herein are methods of depleting T cells for therapeutic use... |
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Invention
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Amatoxin and amatoxin conjugates for use in inhibition of rna virus replication. The present appl... |
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Invention
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Method for synthesis of thioether-containing peptides.
The present invention relates to a method... |
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Invention
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Method for synthesis of thioether-containing peptides. The present invention relates to a method ... |
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Invention
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Compositions and methods for the depletion of cd5+ cells. The invention provides anti-CD5 antibod... |
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Invention
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Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy. The invention provides ... |
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Invention
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Use of anti-cd137 antibody drug conjugate (adc) in allogeneic cell therapy. The invention provide... |
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Invention
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Method for synthesizing amanitins. The invention relates to novel methods for synthesizing amanit... |
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2020
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Invention
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Synthesis of amanin and its derivatives.
The present invention relates to the chemical synthesis... |
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Invention
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Synthesis of amanin and its derivatives. The present invention relates to the chemical synthesis ... |
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Invention
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B-lymphocyte specific amatoxin antibody conjugates.
The present application relates to a conjuga... |
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Invention
|
B-lymphocyte specific amatoxin antibody conjugates. The present application relates to a conjugat... |
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Invention
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B-lymphocyte specific amatoxin antibody conjugates. i.ei.e., a CD20-binding moiety, and optionall... |
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Invention
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Antibody drug conjugates with cleavable linkers. The present invention relates to prodrugs compri... |
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Invention
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Amatoxin antibody-drug conjugates and uses thereof. Amatoxins, as well as antibody-drug conjugate... |
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2019
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Invention
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Synthesis of (s)-6-hydroxytryptophan and derivatives thereof. The present invention relates to no... |
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Invention
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Humanized antibodies against psma. The present application relates to humanized and/or deimmunize... |
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P/S
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Pharmaceutical preparations, namely, anti-cancer and immunosuppression preparations; pharmaceutic... |
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Invention
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Targeted amatoxin conjugate for the treatment of solid tumors. 5 is absent or ═O, wherein R3 and ... |
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2018
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P/S
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Pharmaceutical preparations; Pharmaceuticals; Chemico-pharmaceutical preparations; Pharmaceutical... |
