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2024
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P/S
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pharmaceutical preparations for human use, namely, medications to treat cardiovascular conditions... |
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P/S
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Downloadable electronic publications, namely, newsletters, speaker communications, magazines, cat... |
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P/S
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Pharmaceutical preparations for the treatment of cardiovascular, heart and muscle diseases and di... |
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Invention
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Treatment of heart failure with dosage regimens of omecamtiv mecarbil. Methods for treating heart... |
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P/S
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pharmaceutical preparations for human use, namely medications to treat cardiovascular conditions;... |
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P/S
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Pharmaceutical preparations for human use, namely, medications to treat cardiovascular conditions... |
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Invention
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Bicyclic 1,4-diazepanones and therapeutic uses thereof.
Provided herein are compounds of formula... |
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Invention
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Cardiac sarcomere inhibitors.
Provided are compounds of Formula (I):
Provided are compounds of... |
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P/S
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pharmaceutical preparations for the treatment of cardiovascular diseases and disorders |
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Invention
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Salt of omecamtiv mecarbil and process for preparing salt.
Provided are omecamtiv mecarbil dihyd... |
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Invention
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Salts and crystal forms of omecamtiv mecarbil.
Provided herein are free base crystalline forms, ... |
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2023
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Invention
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Nampt modulators.
Provided are compounds of Formula (I):
Provided are compounds of Formula (I)... |
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Invention
|
Nampt modulators. Provided are compounds of Formula (I): or a pharmaceutically acceptable salt th... |
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Invention
|
Heterocyclic compounds and their uses.
Provided are certain pharmaceutical formulations of omeca... |
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Invention
|
Synthesis of reldesemtiv. Provided herein is a process for the preparation of reldesemtiv and sal... |
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Invention
|
Process for preparing aficamten.
Provided herein is a process for the preparation of (R)-N-(5-(5... |
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Invention
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Crystalline forms of 5-(3,4-difluorobenzyl)-8-((1r,4r)-4-methylcyclohexyl)-6,9-dioxo-2,5,8-triaza... |
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Invention
|
Bisamide sarcomere activating compounds and uses thereof.
The present invention provides a compo... |
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Invention
|
Indane and coumaran derivatives as fast skeletal muscle myosin inhibitors. Provided are compounds... |
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Invention
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Methods for treating obstructive hypertrophic cardiomyopathy.
Methods for treating symptomatic o... |
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Invention
|
Methods for treating obstructive hypertrophic cardiomyopathy. Methods for treating symptomatic ob... |
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Invention
|
Methods for treating non-obstructive hypertrophic cardiomyopathy.
Methods for treating non-obstr... |
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Invention
|
Methods for treating non-obstructive hypertrophic cardiomyopathy. Methods for treating non-obstru... |
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Invention
|
Methods for treating heart failure by administering cardiac sarcomere activators. Methods for tre... |
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Invention
|
Slow skeletal troponin activators. Provided herein are compounds of Formula (I) and pharmaceutica... |
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Invention
|
Methods of treating heart failure with cardiac sarcomere activators. Provided herein are methods ... |
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Invention
|
Bicyclic piperazinones and therapeutic uses thereof. Provided herein are compounds of formula (I)... |
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P/S
|
Pharmaceutical preparations for human use, namely medications to treat cardiovascular conditions;... |
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Invention
|
Methods of treating heart failure with cardiac sarcomere activators.
Provided herein are methods... |
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P/S
|
Human pharmaceuticals for the treatment of cardiovascular diseases, pulmonary diseases, pulmonary... |
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P/S
|
Printed materials, namely, newsletters in the field of cardiovascular diseases and conditions, sp... |
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2022
|
Invention
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Tetrahydroisoquinoline derivatives.
Novel tetrahydroisoquinoline derivative compounds are disclo... |
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Invention
|
Cardiac sarcomere inhibitors. Provided are compounds of Formula (I):
3 are as defined herein.
... |
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Invention
|
Process for preparing aficamten. Provided herein is a process for the preparation of (R)-N-(5-(5-... |
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|
Invention
|
Process for preparing aficamten. Provided herein is a process for the preparation of (R)—N-(5-(5-... |
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Invention
|
Methods for treating hypertrophic cardiomyopathy.
Methods for treating obstructive hypertrophic ... |
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Invention
|
Methods for treating hypertrophic cardiomyopathy. Methods for treating obstructive hypertrophic c... |
|
|
Invention
|
Cd38 modulators and methods of use thereof.
Provided is a compound of formula (I):
Provided is... |
|
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Invention
|
Cd38 modulators and methods of use thereof. Provided is a compound of formula (I): or a stereoiso... |
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P/S
|
Human pharmaceuticals for the treatment of neurological and musculoskeletal diseases and conditio... |
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|
Invention
|
Heterocyclic compounds and their uses. Provided are certain pharmaceutical formulations of omecam... |
|
|
Invention
|
Amino-pyrimidine skeletal muscle modulators.
Provided are compounds of Formula I:
Provided are... |
|
|
Invention
|
Cardiac sarcomere inhibitors. Provided are compounds of Formula (I):
5 are as defined herein. Al... |
|
|
Invention
|
Sulfonamide compounds as cardiac sarcomere activators.
The present disclosure relates to sulfona... |
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P/S
|
human pharmaceuticals for the treatment of pulmonary diseases, pulmonary conditions, bronchoconst... |
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P/S
|
human pharmaceuticals for the treatment of cardiovascular diseases, diseases and conditions assoc... |
|
|
Invention
|
Cardiac sarcomere inhibitors. Provided are compounds of Formula (I):
4 are as defined herein. Al... |
|
|
Invention
|
Cardiac sarcomere inhibitors. Provided are compounds of Formula (I): or stereoisomer or tautomer ... |
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2021
|
Invention
|
Pyrazole derivatives useful as nampt modulators.
Provided herein are compounds of formula (A): o... |
|
|
Invention
|
Bicyclic 1,4-diazepanones and therapeutic uses thereof. Provided herein are compounds of formula ... |
|
|
Invention
|
Nampt modulators.
Provided are compounds of Formula (II): or a pharmaceutically acceptable salt ... |
|
|
Invention
|
Nampt modulators.
Provided are compounds of Formula (II) or a pharmaceutically acceptable salt t... |
|
2020
|
P/S
|
Pharmaceutical preparations, pharmaceutical preparations for the treatment of cardiovascular dise... |
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P/S
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Pharmaceutical preparations for the treatment of cardiovascular diseases; pharmaceutical preparat... |
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Invention
|
Polymorphs of (r)-n-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1h-inden-1-yl)-1-methyl-1h-pyra... |
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Invention
|
Polymorphs of 1-(2-((((trans)-3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl)methyl)amino)pyrimidin-... |
|
2019
|
P/S
|
human pharmaceuticals for the treatment of neurological diseases and conditions, neuromuscular di... |
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2014
|
P/S
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Pharmaceuticals. Computer software used in the collection, analysis and presentation of medical, ... |
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P/S
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Human pharmaceuticals for the treatment of cardiovascular diseases, [ pulmonary diseases, pulmona... |
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2009
|
P/S
|
Pharmaceutical preparations, namely, human pharmaceuticals for the treatment of cancers, cardiova... |
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P/S
|
[ Technical consulting and ] research in the field of cellular assay screening and pharmaceutical... |
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P/S
|
Pharmaceutical and veterinary preparations, namely, human and veterinary pharmaceuticals for the ... |
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P/S
|
Pharmaceutical and veterinary preparations; human and veterinary pharmaceuticals for the treatmen... |
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P/S
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Human pharmaceuticals for the treatment of neurological diseases and conditions, neuromuscular di... |
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2003
|
P/S
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Oncologic, cardiovascular, infectious disease, neurologic, anti-inflammatory, and ophthalmologica... |
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1999
|
P/S
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Consultation and research services relating to drug discovery. |
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P/S
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Consultation and collaboration relating to drug discovery and patient diagnosis; scientific resea... |
