2024
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Invention
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Bicyclic and monocyclic trpa1 inhibitors. A compound of Formula I or II or a pharmaceutically acc... |
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Invention
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Bicyclic imide compounds as trpa1 inhibitors. A compound of Formula (I) or a pharmaceutically acc... |
2023
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Invention
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Pyridone compounds as trpa1 inhibitors. A compound of Formula (I) or a pharmaceutically acceptabl... |
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Invention
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N3-substituted uracil compounds as trpa1 inhibitors. A compound of Formula (I) or a pharmaceutica... |
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Invention
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Pyridazinone compounds as trpa1 inhibitors. A compound of Formula (I) or a pharmaceutically accep... |
2022
|
Invention
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Shp2 phosphatase inhibitors and methods of use thereof.
The present disclosure relates to novel ... |
|
Invention
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Joint generation of a molecular graph and three-dimensional geometry.
A machine-learning approac... |
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Invention
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Joint generation of a molecular graph and three-dimensional geometry. A machine-learning approach... |
|
Invention
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Pi3k-alpha inhibitors and methods of use thereof. The present disclosure relates to novel compoun... |
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Invention
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Spiroindolinone compounds as kv1.3 potassium shaker channel blockers.
A compound of Formula (I) ... |
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Invention
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Spiroindolinone compounds as kv1.3 potassium shaker channel blockers. A compound of Formula (I) o... |
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Invention
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Aryl heterocyclic compounds as kv1.3 potassium shaker channel blockers.
A compound of Formula I
... |
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Invention
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Aryl heterocyclic compounds as kv1.3 potassium shaker channel blockers. A compound of Formula (I)... |
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Invention
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Multibody simulation.
Improvements in a molecular-dynamic simulator provide ways to save energy ... |
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Invention
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Multibody simulation. Improvements in a molecular-dynamic simulator provide ways to save energy d... |
2021
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Invention
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Src inhibitors and uses thereof. The present invention relates to compounds and methods useful fo... |
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Invention
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Lactam compounds as kv1.3 potassium shaker channel blockers.
A compound of Formula (I), or a pha... |
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Invention
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Lactam compounds as kv1.3 potassium shaker channel blockers. A compound of Formula (I), or a phar... |
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Invention
|
Pi3k-alpha inhibitors and methods of use thereof.
The present disclosure relates to novel compou... |
|
Invention
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Pi3k.alpha. inhibitors and methods of use thereof. The present disclosure relates to novel compou... |
|
Invention
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Pi3k-α inhibitors and methods of use thereof. The present disclosure relates to novel compounds a... |
2020
|
Invention
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Arylmethylene aromatic compounds as kv1.3 potassium shaker channel blockers.
A compound of Formu... |
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Invention
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Aryl heterobicyclic compounds as kv1.3 potassium shaker channel blockers.
A compound of Formula ... |
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Invention
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Aryl heterocyclic compounds as kv1.3 potassium shaker channel blockers.
A compound of Formula (I... |
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Invention
|
Arylmethylene heterocyclic compounds as kv1.3 potassium shaker channel blockers.
A compound of F... |
|
Invention
|
Arylmethylene heterocyclic compounds as kv1.3 potassium shaker channel blockers. A compound of Fo... |
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Invention
|
Aryl heterobicyclic compounds as kv1.3 potassium shaker channel blockers. A compound of Formula (... |
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Invention
|
Arylmethylene aromatic compounds as kv1.3 potassium shaker channel blockers. A compound of Formul... |
|
Invention
|
Molecular graph generation from structural features using an artificial neural network.
Discover... |
|
Invention
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Molecular graph generation from structural features using an artificial neural network. Discoveri... |
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Invention
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Fgfr inhibitors and methods of use thereof.
The present disclosure relates to novel compounds an... |
|
Invention
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Fgfr inhibitors and methods of use thereof. The present disclosure relates to novel compounds and... |
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Invention
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Heterocyclic compounds and their use in the treatment of amyloid-related diseases.
A compound of... |
2019
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Invention
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Pyrazolo[3,4-b]pyrazine shp2 phosphatase inhibitors and methods of use thereof. The present discl... |
2018
|
Invention
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Compounds as ras inhibitors and use thereof.
A compound of Formula (Ia) or (Ib), or a pharmaceut... |
2016
|
Invention
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Method of treating neurodegenerative disorders by rescuing alpha-synuclein toxicity.
A method fo... |