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2025
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P/S
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Pharmaceuticals. |
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P/S
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Pharmaceuticals |
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Invention
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Compositions and methods for modulating tau expression. Described are Microtubule-associated prot... |
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Invention
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Chemically modified oligonucleotides and conjugates and methods thereof. Described herein are oli... |
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Invention
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Compositions and methods for modulating alpha-synuclein expression. Provided herein are SNCA anti... |
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2024
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P/S
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Pharmaceuticals; pharmaceutical preparations for diagnosing and treating neurodegenerative diseas... |
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P/S
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Pharmaceutical preparations for diagnosing and treating neurodegenerative diseases; pharmaceutica... |
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Invention
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Fusion proteins comprising acid alpha-glucosidase enzymes and methods thereof. Provided herein ar... |
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Invention
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Modified glucocerebrosidase polypeptides and methods of use thereof. Certain embodiments provide ... |
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Invention
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Kinase inhibitors and uses thereof.
The present disclosure relates generally to compounds and co... |
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Invention
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Compounds, compositions and methods.
The present disclosure relates generally to eukaryotic init... |
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Invention
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Formulation, solid dosage form, and methods. The present disclosure relates generally to a granul... |
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Invention
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Anti-pilra antibodies, uses thereof, and related methods and reagents. e.g.,e.g., monkeys) withou... |
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Invention
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Compositions and methods for modulating tau expression. Provided herein are MAPT antisense oligon... |
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Invention
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Dual transporters and methods of use. Described are dual transporters and methods of making and u... |
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Invention
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Compounds, compositions, and methods.
The present disclosure relates generally to LRRK2 inhibito... |
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Invention
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Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2,3,4,5-tetrahydropyrido [3,2-b][1,4]oxazepin... |
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Invention
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Methods of engineering transferrin receptor binding polypeptides. Provided herein are polypeptide... |
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Invention
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Methods of increasing sialic acid levels in recombinant glycosylated proteins. Provided herein ar... |
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Invention
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Abeta-targeting proteins and methods of use. Described are Abeta-targeting proteins comprising an... |
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Invention
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Solid forms of 4-(3,3-difluoro-2,2-dimethyl-propanoyl)-3,5-dihydro-2h-pyrido[3,4-f][1,4]oxazepine... |
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Invention
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Methods of engineering transferrin receptor binding polypeptides.
Provided herein are polypeptid... |
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Invention
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Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof.
Provided... |
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2023
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Invention
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Methods and compositions related to engineered transferrin receptor‑binding molecules. e.g.,e.g.,... |
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Invention
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Cd98 heavy chain transgenic models. In some aspects, the present disclosure provides CD98hc polyp... |
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Invention
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Compounds, compositions, and methods. The present disclosure relates generally to small molecule ... |
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Invention
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Modulators of eukaryotic initiation factor 2.
The present disclosure relates generally to eukary... |
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Invention
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Processes and intermediates for the preparation of a pyrimidine aminopyrazole compound. N22HHNN 4... |
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Invention
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Solid and co-crystal forms of a pyrimidine triazole compound. The present disclosure relates to c... |
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Invention
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Process for the preparation of pyrimidinyl-4-aminopyrazole compounds.
The present disclosure rel... |
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Invention
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Engineered transferrin receptor binding polypeptides.
Provided herein are polypeptides that bind... |
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Invention
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Compounds, compositions and methods. The present disclosure relates generally to compounds and co... |
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Invention
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Solid forms of 4-(3,3-difluoro-2,2-dimethyl-propanoyl)-3,5- dihydro-2h-pyrido[3,4-f][l,4]oxazepin... |
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Invention
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Transferrin receptor binding molecule conjugates for delivery of oligonucleotides to cells |
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Invention
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Transferrin receptor binding molecule conjugates for delivery of oligonucleotides to cells. Provi... |
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Invention
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Monovalent anti-trem2 binding molecules and methods of use thereof.
In one aspect, monovalent bi... |
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2022
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Invention
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Polypeptide engineering, libraries, and engineered cd98 heavy chain and transferrin receptor bind... |
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Invention
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Fusion proteins comprising alpha-l-iduronidase enzymes and methods.
Provided herein are proteins... |
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Invention
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Microglial cell morphometry.
Methods and systems described herein may allow for the classificati... |
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Invention
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Anti-her2 antibodies and methods of use thereof.
In one aspect, antibodies that bind to subdomai... |
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Invention
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Engineered anti-her2 bispecific proteins.
In one aspect, bispecific proteins having the ability ... |
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Invention
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Methods for the treatment of hunter syndrome.
Certain embodiments provide a method of providing ... |
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Invention
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Oligonucleotide conjugates targeted to the transferrin receptor.
Provided herein are conjugates ... |
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Invention
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Methods for treating and monitoring parkinson's disease.
The present disclosure relates to metho... |
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Invention
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Anti-transferrin receptor fusion proteins and methods of use thereof.
Certain embodiments provid... |
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2021
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Invention
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Solid forms of a compound.
Forms of 2-(4-chlorophenoxy)-N-[3-[5-[cis-3-(trifluoromethoxy)cyclobu... |
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Invention
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Methods for treating and monitoring frontotemporal dementia.
The present disclosure provides met... |
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P/S
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pharmaceutical preparations for diagnosing and treating neurodegenerative diseases. scientific re... |
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P/S
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Pharmaceutical preparations for diagnosing and treating neurodegenerative diseases Scientific res... |
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2019
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P/S
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scientific research, pharmaceutical research, medical research, technical consultation and produc... |
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2017
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P/S
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pharmaceutical preparations for diagnosing and treating diseases of the central nervous system |
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P/S
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pharmaceutical preparations for diagnosing and treating neurodegenerative diseases |
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2015
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P/S
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Pharmaceutical preparations for diagnosing and treating neurodegenerative diseases namely, centra... |
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P/S
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Pharmaceutical preparations for diagnosing and treating
neurodegenerative diseases. Scientific r... |
