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2025
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Invention
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Differential knockout of an allele of a heterozygous elane gene.
Methods for inactivating in a c... |
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Invention
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Differential knockout of an allele of a heterozygous elane gene - ii.
RNA, compositions, and met... |
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Invention
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Differential knockout of an allele of a heterozygous fibrinogen alpha chain (fga) gene.
RNA mole... |
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Invention
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Knockout of a mutant allele of an elane gene.
Methods for inactivating in a cell a mutant allele... |
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2024
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Invention
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Guide rna that targets a mutant human guanylate cyclase 2a allele.
Methods for inactivating a mu... |
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Invention
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Methods and compositions for modifying expression of a mutant transforming growth factor beta ind... |
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Invention
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Compositions and methods for promoting gene editing of cxcr4 gene.
RNA molecules comprising a gu... |
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Invention
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Omni-103 crispr nuclease. The present invention provides a non-naturally occurring composition co... |
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Invention
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Strategies for knock-ins at aavs1 safe harbor sites. RNA molecules comprising a guide sequence po... |
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Invention
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Strategies for knock-ins at rosa26 safe harbor sites. RNA molecules comprising a guide sequence p... |
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Invention
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Engineered omni-50 nuclease variants. The present invention provides a composition comprising a n... |
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Invention
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Novel omni-59, 61, 67, 76, 79, 80, 81 and 82 crispr nucleases.
The present invention provides a ... |
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Invention
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Omni xl 1-22 crispr nucleases. The present invention provides a non-naturally occurring compositi... |
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2023
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Invention
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Omni-335 crispr nuclease. The present invention provides a non-naturally occurring composition co... |
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Invention
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Compositions and methods for transcription factor 4 (tcf4) repeat expansion excision. RNA molecul... |
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Invention
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Differential knockout of an allele of a heterozygous bestrophin 1 gene.
RNA molecules comprising... |
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Invention
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Compositions for genome editing.
The present invention relates to compositions and methods for i... |
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Invention
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Biallelic knockout of ciita.
Compositions comprising an RNA molecule comprising a guide sequence... |
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Invention
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Biallelic knockout of ciita. Compositions comprising an RNA molecule comprising a guide sequence ... |
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Invention
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Biallelic knockout of cish.
Compositions comprising an RNA molecule comprising a guide sequence ... |
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Invention
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Biallelic knockout of ctla4.
Compositions comprising an RNA molecule comprising a guide sequence... |
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Invention
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Biallelic knockout of pdcd1.
Compositions comprising an RNA molecule comprising a guide sequence... |
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Invention
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Biallelic knockout of tet2. Compositions comprising an RNA molecule comprising a guide sequence p... |
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Invention
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Biallelic knockout of hla-e. Compositions comprising an RNA molecule comprising a guide sequence ... |
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Invention
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Biallelic knockout of cish. Compositions comprising an RNA molecule comprising a guide sequence p... |
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Invention
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Biallelic knockout of pdcd1. Compositions comprising an RNA molecule comprising a guide sequence ... |
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Invention
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Biallelic knockout of ctla4. Compositions comprising an RNA molecule comprising a guide sequence ... |
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Invention
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Biallelic knockout of faslg. Compositions comprising an RNA molecule comprising a guide sequence ... |
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Invention
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Strategies for knock-ins at b2m safe harbor sites. RNA molecules comprising a guide sequence port... |
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Invention
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Biallelic knockout of angptl3. RNA molecules comprising a guide sequence portion consisting of 17... |
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Invention
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Strategies for knock-ins at aplp2 safe harbor sites.
RNA molecules comprising a guide sequence p... |
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Invention
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Strategies for knock-ins at aplp2 safe harbor sites. RNA molecules comprising a guide sequence po... |
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Invention
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Novel omni-50 crispr nuclease.
The present invention provides a non-naturally occurring composit... |
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2022
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Invention
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Omni-103 crispr nuclease-rna complexes.
A composition comprising a non-naturally occurring RNA m... |
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Invention
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Reduced expression of sarm1 for use in cell therapy.
The invention relates to a method for adopt... |
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Invention
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Engineered high activity omni-79 nuclease variants.
The present invention is directed to, inter ... |
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Invention
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Omni 263, 264, 266, 268, 269, 271, 274, 275, 276, 278, 279, 280, 281, 283, 284, 286, 287, 288, 29... |
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Invention
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Engineered high fidelity omni-50 nuclease variants.
The present invention is directed to, inter ... |
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Invention
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Novel omni 115, 124, 127, 144-149, 159, 218, 237, 248, 251-253 and 259 crispr nucleases.
The pre... |
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Invention
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Hepatitis b virus (hbv) knockouts.
RNA molecules comprising a guide sequence portion having 17-5... |
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Invention
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Novel omni 117, 140, 150-158, 160-165, 167-177, 180-188, 191-198, 200, 201, 203, 205-209, 211-217... |
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Invention
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Compositions and methods for treating hypercholesterolemia.
RNA molecules comprising a guide seq... |
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Invention
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Strategies for knock-ins at c3 safe harbor sites.
RNA molecules comprising a guide sequence port... |
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Invention
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Omni 90-99, 101, 104-110, 114, 116, 118-123, 125, 126, 128, 129, and 131-138 crispr nuclease.
Th... |
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2021
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Invention
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Biallelic knockout of trac.
RNA molecules comprising a guide sequence portion having 17-50 conti... |
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Invention
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Biallelic knockout of b2m.
RNA molecules comprising a guide sequence portion having 17-50 contig... |
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P/S
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Enzymes for scientific and research purposes; nucleases and nuclease panels for scientific and re... |
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Invention
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Differential knockout of a heterozygous allele of lrrk2.
RNA molecules comprising a guide sequen... |
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Invention
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Novel omni-50 crispr nuclease-rna complexes.
A composition comprising a non-naturally occurring ... |
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Invention
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Novel omni 56, 58, 65, 68, 71, 75, 78, and 84 crispr nucleases.
The present invention provides a... |
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Invention
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Differential knockout of a heterozygous allele of samd9.
RNA molecules comprising a guide sequen... |
