Merck Sharp & Dohme Limited

Royaume‑Uni

 
Quantité totale PI 73
Rang # Quantité totale PI 18 336
Note d'activité PI 1,1/5.0    3
Rang # Activité PI 339 187
Parent Merck & Co., Inc.

Brevets

Marques

7 0
2 0
64 0
0
 
Dernier brevet 2024 - Controlled release pde10a formul...
Premier brevet 1986 - Use of specific n-methyl-d-aspar...

Derniers inventions, produits et services

2024 Invention Controlled release pde10a formulations. NSSS)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimid...
2020 Invention Process for the preparation of intermediates useful for making (2s,5r)-7-oxo-n-piperidin-4-yl-6-(...
2018 Invention Pegylated interleukin-10. Interleukin-10 (IL-10) conjugated via a linker to one or more polyethyl...
2017 Invention Methods for treatment of cancer with therapeutic combinations comprising peg-il-10. Provided are ...
Invention Methods of preparing hydroxylamine derivatives useful in the preparation of anti-infective agents...
2016 Invention Process for making m1 receptor positive allosteric modulators. This invention provides novel proc...
Invention 4'-substituted nucleoside reverse transcriptase inhibitors and preparations thereof. The present ...
2015 Invention Substituted phosphoramidate compounds and uses thereof. The present invention is directed to Comp...
Invention Process for making tetracyclic heterocycle compounds. The present invention is directed to a pro...
Invention Process for making tetracyclic heterocycle compounds. The present invention is directed to a proc...
2014 Invention Oral pharmaceutical formulation of omarigliptin. The present invention is directed to stable, ora...
2012 Invention Crystal forms of a hcv protease inhibitor. The present invention relates to different forms of a ...
Invention Methods and intermediates for preparing macrolactams. The present invention includes compounds us...
Invention Process for preparing chiral dipeptidyl peptidase-iv inhibitors. A process for the preparation of...
Invention Novel crystalline forms of a dipeptidyl peptidase-iv inhibitor. Novel crystalline forms of (2R,3S...
Invention Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with simvastatin...
Invention Process for the preparation of an orexin receptor antagonist. The present invention is directed t...
2010 Invention Formulations for c-met kinase inhibitors. The instant invention relates to pharmaceutical composi...
Invention Crystalline hydrochloride salts of c-met kinase inhibitors. The instant invention relates to crys...
2009 Invention Cyclohexanesulfonyl derivatives as glyt1 inhibitors to treat schizophrenia. The present invention...
Invention Use of nmda activity enhancers to treat hypersomnia, reduced wakefulness or reduced vigilance. T...
Invention Use of nmda activity enhancers to treat hypersomnia, reduced wakefulness or reduced vigilance. Th...
Invention Substituted dihydroisoquinolinone and isoquinolinedione derivatives as calcium channel blockers. ...
Invention 3, 4 - substituted piperidine derivatives as renin inhibitors. The present invention relates to 3...
2008 Invention Methods for predicting treatment response based on the expression profiles of biomarker genes in ...
Invention Use of erythropoietin to develop small molecule inhibitors of janus kinase-2. The invention pert...
Invention Igf-1r specific antibodies useful in the detection and diagnosis of cellular proliferative disord...
2007 Invention Imidazothiazole derivatives as mark inhibitors. Compounds of formula (I): are inhibitors of MARK...
Invention Aminothiazole derivatives as inhibitors of mark. Compounds of formula (I): inhibit microtubule a...
Invention 3-animopyraolines for treatment of neurodegenerative and psychiatric diseases. Compounds of the ...
Invention Indazole derivatives for treatment of alzheimer's disease. Compounds of formula (IA) and (IB) ar...
Invention Upregulation of adamts4 protease activity for the treatment of alzheimer's disease. The inventio...
Invention Treatment of alzheimer's disease and related conditions. Compounds of formula (I) inhibit microt...
2006 Invention Tetrahydroindole derivatives for treatment of alzheimer's disease. Tetrahydroindole derivatives o...
Invention Method for identifying modulators of gamma secretase or notch. The present invention relates to ...
Invention Process for the preparation of bicyclo[3.1.0]hexanols. 3-7 cycloalkenyl ring.
Invention Mutants of human app and their use for the production of transgenice animals. A modified amyloid...
Invention Inhibitors of glyt1 transporters. 4, Ar, A, n and m are defined herein, is disclosed as a GlyT1 i...
Invention Sulphone derivatives for treatment of cancer. Compounds of Formula (I) are disclosed for treatme...
Invention 2,3-substituted fused bicyclic pyrimidin-4(3h)-ones which modulating the function of the vanilloi...
Invention Process for the preparation of tetrazolytetrahydrocyclopentapyrazoles. 2 are linked and, together...
Invention 2,3-substituted fused pyrimidin -4 (3h)-ones as vr1 antagonists. A compound of formula (I), wher...