2024
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Invention
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Controlled release pde10a formulations. NSSS)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimid... |
2020
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Invention
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Process for the preparation of intermediates useful for making (2s,5r)-7-oxo-n-piperidin-4-yl-6-(... |
2018
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Invention
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Pegylated interleukin-10. Interleukin-10 (IL-10) conjugated via a linker to one or more polyethyl... |
2017
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Invention
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Methods for treatment of cancer with therapeutic combinations comprising peg-il-10. Provided are ... |
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Invention
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Methods of preparing hydroxylamine derivatives useful in the preparation of anti-infective agents... |
2016
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Invention
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Process for making m1 receptor positive allosteric modulators. This invention provides novel proc... |
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Invention
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4'-substituted nucleoside reverse transcriptase inhibitors and preparations thereof. The present ... |
2015
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Invention
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Substituted phosphoramidate compounds and uses thereof. The present invention is directed to Comp... |
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Invention
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Process for making tetracyclic heterocycle compounds.
The present invention is directed to a pro... |
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Invention
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Process for making tetracyclic heterocycle compounds. The present invention is directed to a proc... |
2014
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Invention
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Oral pharmaceutical formulation of omarigliptin. The present invention is directed to stable, ora... |
2012
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Invention
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Crystal forms of a hcv protease inhibitor. The present invention relates to different forms of a ... |
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Invention
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Methods and intermediates for preparing macrolactams. The present invention includes compounds us... |
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Invention
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Process for preparing chiral dipeptidyl peptidase-iv inhibitors. A process for the preparation of... |
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Invention
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Novel crystalline forms of a dipeptidyl peptidase-iv inhibitor. Novel crystalline forms of (2R,3S... |
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Invention
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Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with simvastatin... |
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Invention
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Process for the preparation of an orexin receptor antagonist. The present invention is directed t... |
2010
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Invention
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Formulations for c-met kinase inhibitors. The instant invention relates to pharmaceutical composi... |
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Invention
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Crystalline hydrochloride salts of c-met kinase inhibitors. The instant invention relates to crys... |
2009
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Invention
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Cyclohexanesulfonyl derivatives as glyt1 inhibitors to treat schizophrenia. The present invention... |
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Invention
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Use of nmda activity enhancers to treat hypersomnia, reduced wakefulness or reduced vigilance.
T... |
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Invention
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Use of nmda activity enhancers to treat hypersomnia, reduced wakefulness or reduced vigilance. Th... |
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Invention
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Substituted dihydroisoquinolinone and isoquinolinedione derivatives as calcium channel blockers. ... |
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Invention
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3, 4 - substituted piperidine derivatives as renin inhibitors. The present invention relates to 3... |
2008
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Invention
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Methods for predicting treatment response based on the expression profiles of biomarker genes in ... |
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Invention
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Use of erythropoietin to develop small molecule inhibitors of janus kinase-2.
The invention pert... |
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Invention
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Igf-1r specific antibodies useful in the detection and diagnosis of cellular proliferative disord... |
2007
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Invention
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Imidazothiazole derivatives as mark inhibitors.
Compounds of formula (I): are inhibitors of MARK... |
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Invention
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Aminothiazole derivatives as inhibitors of mark.
Compounds of formula (I): inhibit microtubule a... |
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Invention
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3-animopyraolines for treatment of neurodegenerative and psychiatric diseases.
Compounds of the ... |
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Invention
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Indazole derivatives for treatment of alzheimer's disease.
Compounds of formula (IA) and (IB) ar... |
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Invention
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Upregulation of adamts4 protease activity for the treatment of alzheimer's disease.
The inventio... |
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Invention
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Treatment of alzheimer's disease and related conditions.
Compounds of formula (I) inhibit microt... |
2006
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Invention
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Tetrahydroindole derivatives for treatment of alzheimer's disease. Tetrahydroindole derivatives o... |
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Invention
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Method for identifying modulators of gamma secretase or notch.
The present invention relates to ... |
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Invention
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Process for the preparation of bicyclo[3.1.0]hexanols. 3-7 cycloalkenyl ring.
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Invention
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Mutants of human app and their use for the production of transgenice animals.
A modified amyloid... |
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Invention
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Inhibitors of glyt1 transporters. 4, Ar, A, n and m are defined herein, is disclosed as a GlyT1 i... |
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Invention
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Sulphone derivatives for treatment of cancer.
Compounds of Formula (I) are disclosed for treatme... |
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Invention
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2,3-substituted fused bicyclic pyrimidin-4(3h)-ones which modulating the function of the vanilloi... |
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Invention
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Process for the preparation of tetrazolytetrahydrocyclopentapyrazoles. 2 are linked and, together... |
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Invention
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2,3-substituted fused pyrimidin -4 (3h)-ones as vr1 antagonists.
A compound of formula (I), wher... |