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2016
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Invention
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Polynucleotides containing a stabilizing tail region. The invention features polynucleotides enco... |
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Invention
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Polynucleotides containing a morpholino linker. The disclosure provides polynucleotides encoding ... |
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Invention
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Polynucleotide formulations for use in the treatment of renal diseases. The present invention rel... |
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Invention
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Modified nucleic acid molecules and uses thereof.
The present disclosure provides modified nucle... |
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Invention
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Lipid nanoparticle compositions. Disclosed herein are nanoparticle compositions including an mRNA... |
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2015
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Invention
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Alternative nucleic acid molecules containing reduced uracil content and uses thereof. The presen... |
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Invention
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Tolerogenic compositions and methods. The invention relates to tolerogenic compositions and metho... |
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Invention
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Chimeric polynucleotides. The invention relates to compositions and methods for the preparation, ... |
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Invention
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Circular polynucleotides. The invention relates to compositions and methods for the preparation, ... |
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Invention
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Alternative nucleic acid molecules and uses thereof.
The present disclosure provides alternative... |
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Invention
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Alternative nucleic acid molecules and uses thereof. The present disclosure provides alternative ... |
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Invention
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Engineered nucleic acids and methods of use thereof.
Provided are compositions and methods for d... |
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Invention
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Polynucleotides for the in vivo production of antibodies. The invention relates to compositions a... |
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2014
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Invention
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Modified nucleic acid molecules and uses thereof. The present disclosure provides modified nucleo... |
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Invention
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Targeted adaptive vaccines. The invention relates to compositions and methods for the preparation... |
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Invention
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Engineered nucleic acids and methods of use thereof. Provided are compositions and methods for de... |
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Invention
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Compositions and methods for tolerizing cellular systems. The invention relates to compositions a... |
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Invention
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Polynucleotides encoding low density lipoprotein receptor. The invention relates to compositions ... |
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Invention
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Polynucleotide molecules and uses thereof. The present disclosure provides alternative nucleoside... |
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Invention
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Polynucleotide molecules and uses thereof. The present disclosure provides alternative sugar moie... |
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Invention
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Polynucleotides encoding immune modulating polypeptides. The invention relates to compositions an... |
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Invention
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Polynucleotide compositions containing amino acids. The present invention relates to compositions... |
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Invention
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Circular polynucleotides.
The invention relates to compositions and methods for the preparation,... |
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Invention
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Chimeric polynucleotides.
The invention relates to compositions and methods for the preparation,... |
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Invention
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Compositions comprising synthetic polynucleotides encoding crispr related proteins and synthetic ... |
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Invention
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Modified polynucleotides encoding udp glucuronosyltransferase 1 family, polypeptide a1.
The inve... |
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Invention
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Compositions and methods of altering cholesterol levels. The present invention relates to composi... |
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Invention
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Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions. The p... |
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Invention
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Analysis of mrna heterogeneity and stability. Reversed phase - High Performance (High Pressure) L... |
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Invention
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Ion exchange purification of mrna. The current landscape for preparative chromatographic RNA puri... |
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Invention
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Characterization of mrna molecules. The present invention describes methods for the characterizat... |
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Invention
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Long-lived polynucleotide molecules. The invention relates to compositions and methods for the pr... |
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Invention
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Manufacturing methods for production of rna transcripts. Described are methods for production of ... |
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Invention
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Removal of dna fragments in mrna production process. The present invention describes methods of r... |
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Invention
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Ribonucleic acid purification. Disclosed herein are methods for purifying RNA comprising poly A. ... |
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Invention
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Heterologous untranslated regions for mrna. The invention relates to compositions and methods for... |
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Invention
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Diagnosis and treatment of fibrosis. The invention relates to the treatment of fibrosis using mod... |
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2013
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Invention
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Modified polynucleotides encoding caspase 3.
The invention relates to compositions and methods f... |
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Invention
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Modified polynucleotides encoding cytotoxic t-lymphocyte-associated protein 4.
The invention rel... |
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Invention
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Modified polynucleotides encoding programmed cell death 1.
The invention relates to compositions... |
