In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-COV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two-dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
Illustrative embodiments of cellulose nanocrystal modification for adsorbents and sensors are disclosed. In at least one illustrative embodiment, a method of modifying cellulose nanocrystals for use in water-based applications may include obtaining sulfated cellulose nanocrystals (CNCs). The method may also include modifying the CNCs with a silane such as an alkylsilane (e.g., an aminoalkyl silane such as 3-aminopropyl-triethoxysilane (APTES)) to obtain modified CNCs. The modified CNCs enable increased hydrolytic stability (e.g., in a resulting structure, such as a film, coating, gel, or fiber(s), formed from the modified CNCs as compared to a structure formed from the unmodified CNCs). Additionally, the method may include using the modified CNCs in a water-based application.
The invention relates to an HVAC apparatus, method, and system. Aspects of the invention include a supplemental heat source with an air handler unit for a conventional forced air heating and cooling system. The supplemental heat source in one example is a hydronic subsystem. It can be used alone or to supplement the forced air subsystem. Another aspect of the invention includes an air handling subsystem that has a housing that can be highly flexible in configuration and installation. The housing can support internal components, including a hydronic or other supplemental heat source with the forced air components. At least two sides of the housing can be configured for access for maintenance and repair. A control system can be designed to eliminate need for defrost cycle for forced air refrigeration-type subsystem and/or for better maintenance for comfort in the air conditioned space.
An opioid sensor includes a film having two opposed surfaces. The film includes a conductive polymer, and an anchor molecule attached to the conductive polymer so that it is immobilized at a first of the two opposed surfaces. The anchor molecule is to adsorb an opioid. The opioid sensor also includes a working electrode at least partially in contact with a second of the two opposed surfaces; and a counter electrode or counter/reference electrode electrically connected to, and positioned a spaced distance from, the working electrode.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
The United States of America, as represented by the Secretary of Agriculture (USA)
Inventor
Toro Guzman, Haroldo E.
Yu, Qingzhong
Abstract
Disclosed are recombinant Newcastle disease virus (rNDV) vectors, related polynucleotides, and methods for eliciting an immune response against avian infectious bronchitis virus (IBV) or vaccinating against IBV.
Disclosed herein are systems and methods for reliable and verifiable tracking and reporting of value chain data. In one respect, a management system is provided for a value chain platform, configured to: verify digital certificates confirming suppliers' compliance with emissions tracking criteria of the value chain platform; deploy at least one smart contract on a permissioned blockchain of the value chain platform, the smart contract configured to process one or more emissions tokens of upstream suppliers plus emissions data of a current supplier, to automatically mint a new emissions token representing a combination of the two; and generate a report of cumulative emissions for a given product of the value chain, based on the new emissions token.
A method of target molecule detection includes simultaneously obtaining a first signal from a first working electrode and a second signal from a second working electrode, wherein the first signal is responsive to interaction of the first recognition element with the target molecule in a sample, and the second signal is indicative of background noise from the sample. The method further includes generating a modified signal that is proportional to an instantaneous difference between the first and second signals, wherein the modified signal indicates an amount of the target molecule present in the sample.
A system for improving a physical component may include a processor configured to (1) access a first data storage that may include a plurality of function data objects or a plurality of data vessel data objects that may include references to each other; (2) iterate over the plurality of data vessel data objects, and for each data vessel data object, generate one or more data element instance data objects; (3) select a subset of the plurality of data element instance data objects that include the same data element identifier; (4) order the subset of the data element instance data objects based their respective one or more references to one or more other data element instance data objects; and (5) store the ordered subset of the data element instance data objects in a second data storage as a digital thread.
Technologies for automated test pattern generation include a computing device that identifies one or more stuck-at faults in a logic circuit. The computing device inserts a key gate in the logic circuit at a stuck-at fault to generate a locked logic circuit. The computing device performs a Boolean satisfiability attack to determine an input test pattern associated with the fault and, if no input test pattern exists, identify the fault as redundant. The computing device may identify multiple undetected faults in the logic circuit. The computing device may generate and analyze a separate locked circuit for each undetected fault and/or generate and analyze a locked circuit that models all of the undetected faults. The computing device may test a device under test with all of the generated input test patterns associated with the undetected faults. Other embodiments are described and claimed.
Proposed are an apparatus for and a method of controlling energy for a hybrid electric vehicle. The apparatus includes an input module receiving a traveling condition and a vehicular characteristic of the vehicle, a memory storing an execution program and a parameter that are necessary for carrying out an energy management strategy, and a processor operatively coupled to the input module and the memory, wherein the processor receives the traveling condition and the vehicular characteristic through the input module, according to the energy management strategy, and then determines, based on a first control algorithm, whether or not the vehicle is drivable in an EV mode, wherein, when the vehicle is drivable, the processor enables the vehicle to drive in the EV mode, and wherein, when the vehicle is not drivable, the processor determines and outputs a drive mode and a torque distribution ratio based on a second control algorithm.
B60W 20/11 - Controlling the power contribution of each of the prime movers to meet required power demand using model predictive control [MPC] strategies, i.e. control methods based on models predicting performance
B60W 10/06 - Conjoint control of vehicle sub-units of different type or different function including control of propulsion units including control of combustion engines
B60W 10/08 - Conjoint control of vehicle sub-units of different type or different function including control of propulsion units including control of electric propulsion units, e.g. motors or generators
B60W 20/13 - Controlling the power contribution of each of the prime movers to meet required power demand in order to prevent overcharging or battery depletion
11.
WIRELESS SENSOR BASED ON LC RESONATOR FOR MONITORING SOIL WATER CONTENT
In at least one illustrative embodiment, a system for wireless soil humidity sensing includes one or more wireless sensors. Each sensor includes a capacitor and an inductor, the capacitor having a dielectric material with a high relative dielectric permittivity that changes in response to changes in environmental humidity. The dielectric material may be a ceramic material such as a core-shell composite including barium titanate (BaTiO3) and silicon dioxide (SiO2). The capacitor may include two opposing sides, with a pair of electrodes positioned on one of the sides. An encapsulation layer such as epoxy may cover the side of the capacitor having the electrode. Sensors may be distributed throughout the soil in an area such as a farm field. The resonant frequency of one or more wireless sensors may be measured, and relative humidity of the soil may be determined based on the resonant frequency. Other embodiments are described and claimed.
G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
The present disclosure relates to structures and methods of use of textiles for protection, and more particularly. relates to single layer knitted structures that can be worn as garments to block mosquito bites. The knit structures of the present embodiments can include single layer structures having a unique geometric combination of yarn properties and textiles to block mosquito bites in a single. comfortable layer of fabric. The knit structures can include one or more controllable parameters that can be adjusted to increase and/or decrease the bite blocking ability of the knit structure.
A device including a chamber and a nozzle detachably connected to the chamber, the nozzle defining an aperture, a target carousel disposed within the chamber, a first laser configured to generate a first beam directed toward the target carousel to perform in-situ ablation to form a laser plume, a gas flow system configured to supply gas into the chamber, such that the gas interacts with the laser plume and causes condensation and formation of nanoparticles, and a second laser configured to generate a second beam directed through the interior of the chamber, through the aperture of the nozzle, and toward a substrate disposed outside the device, the second laser beam configured to sinter and crystalize on the substrate the nanoparticles exiting the nozzle.
C23C 14/22 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the process of coating
B22F 10/25 - Direct deposition of metal particles, e.g. direct metal deposition [DMD] or laser engineered net shaping [LENS]
B22F 10/34 - Process control of powder characteristics, e.g. density, oxidation or flowability
B22F 12/44 - Radiation means characterised by the configuration of the radiation means
B22F 12/90 - Means for process control, e.g. cameras or sensors
B23K 26/14 - Working by laser beam, e.g. welding, cutting or boring using a fluid stream, e.g. a jet of gas, in conjunction with the laser beam; Nozzles therefor
B23K 26/144 - Working by laser beam, e.g. welding, cutting or boring using a fluid stream, e.g. a jet of gas, in conjunction with the laser beam; Nozzles therefor the fluid stream containing particles, e.g. powder
B33Y 30/00 - ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING - Details thereof or accessories therefor
14.
3D PRINTING OF ADDITIVE-FREE MXENE INK FOR FABRICATION OF MICRO-SUPERCAPACITORS WITH ULTRA-HIGH ENERGY DENSITIES
The disclosure provides ink compositions that comprise a 2D material and a solvent and the method to fabricate such compositions. The disclosure also provides the composition and method of fabricating 3D MSCs comprising such ink compositions. Additionally, the disclosure provides a conducting material comprising a battery composition, a 2D material, and a solvent that results in the formation of a composition that may be used for 3D printing of batteries.
B29C 64/165 - Processes of additive manufacturing using a combination of solid and fluid materials, e.g. a powder selectively bound by a liquid binder, catalyst, inhibitor or energy absorber
B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
B33Y 80/00 - Products made by additive manufacturing
C09D 11/033 - Printing inks characterised by features other than the chemical nature of the binder characterised by the solvent
H01G 11/24 - Electrodes characterised by the structural features of powders or particles used therefor
H01G 11/28 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features arranged or disposed on a current collector; Layers or phases between electrodes and current collectors, e.g. adhesives
H01G 11/38 - Carbon pastes or blends; Binders or additives therein
H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes
15.
METHOD TO MAKE HYDROGELS AND CELLULOSE FROM PECTIN- AND PROTEIN-CONTAINING CELLULOSIC BIOMASS
A method of making a hydrogel by treating a cellulosic biomass containing pectin and protein with an aqueous acidic solution at a pH, at a temperature, and for a time sufficient to cause formation of at least a gel fraction containing the hydrogel.
One or more embodiments relate to custom microfabricated magnetic shields that are configured to provide isolation of superconducting electronics (SCE) circuits/chips from each other and an external environment. Whereas most superconducting circuits require magnetic shielding and most shields work by fully encapsulating the circuits, leaving little access for quite rigid and fragile fibers, one or more embodiments allow custom magnetic shield shapes to be fabricated. In embodiments, to improve the shielding, magnetic vias composed of permalloy can be introduced into the shield design. The vias can connect the magnetic shield to a permalloy layer beneath the silicon substrate.
H05K 9/00 - Screening of apparatus or components against electric or magnetic fields
H01L 23/552 - Protection against radiation, e.g. light
H02K 11/01 - Structural association of dynamo-electric machines with electric components or with devices for shielding, monitoring or protection for shielding from electromagnetic fields
H01L 21/00 - Processes or apparatus specially adapted for the manufacture or treatment of semiconductor or solid state devices or of parts thereof
17.
METHOD AND DEVICE FOR NONDESTRUCTIVELY AND IN-SITU MONITORING CORROSION IN OBJECT
The invention in one aspect relates to a method for nondestructively detecting corrosion of an object such as metallic cables. The method includes applying an electronic signal to a device under test (DUT) including said object; measuring signal-transmission characteristics of said object; and determining the corrosion of the object based on the measured signal-transmission characteristics of said object.
The present invention relates to compositions comprising clofazimine and methods for treating cancer. In various embodiments, the compositions and methods further comprise a proteasome inhibitor and/or immunomodulatory drug. The compositions and methods of the present invention may be used for naïve cancers as well as those that have developed resistance to proteasome inhibitors and/or immunomodulatory drugs.
A61K 31/498 - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
The present disclosure describes genes and proteins of the coenzyme F430 synthetic pathway. The genes and proteins in the pathway find uses as isolated nucleic acids, transformation vectors, a transformation media, genetically modified cells, methods of modulating methanogenesis, methods of modulating methane oxidation, methods of making a tetrapyrrole compound, methods of oxidizing methane, methods of biogenic methane synthesis is provided, methods of assaying an organism for potential methanogenic or methanotrophic activity, and isolated proteins.
Methods of making films with feedstock comprising biomass. The methods include treating a feedstock comprising biomass with an acidic aqueous solution to yield a solid phase and a liquor, generating a forming fluid with the liquor, and generating a film from the forming fluid. Some versions include comminuting the solid phase to generate a comminuted solid phase and including the comminuted solid phase in the forming fluid. The biomass preferably contains relatively high amounts of pectin and protein. The films can be in the form of standalone films or coatings on substrates such as paper. The films provide oil and grease resistance and air impermeability, among other advantages.
A23K 10/30 - Animal feeding-stuffs from material of fungal origin, e.g. mushrooms
A23K 40/10 - Shaping or working-up of animal feeding-stuffs by granulation, e.g. making powders
A23K 10/12 - Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
A61K 49/18 - Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
23.
SHRINKING NANOMATERIAL FOR BIOMEDICAL APPLICATIONS
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A thin-film transistor comprises an annealed layer comprising crystalline zinc oxide. A passivation layer is adjacent to the thin-film transistor. The passivation layer has a thickness and material composition such that when a dose of radiation from a radiation source irradiates the thin-film transistor, a portion of the dose that includes an approximate maximum concentration of the dose is located within the annealed layer. The annealed layer has a thickness and threshold displacement energies after it has been annealed such that: a) a difference between a transfer characteristic value of the thin-film transistor before and after the dose is less than a first threshold; and b) a difference between a transistor output characteristic value of the thin-film before and after the dose is less than a second threshold. The thresholds are based on a desired performance of the thin-film transistor.
H01L 21/477 - Thermal treatment for modifying the properties of semiconductor bodies, e.g. annealing, sintering
H01L 21/768 - Applying interconnections to be used for carrying current between separate components within a device
25.
USING LIBERATED AND MODIFIED FIBERS, MICRO-FIBERS, NANO-FIBERS, AND CELLULOSE FROM LIGNOCELLULOSIC PLANT FIBERS, COMBINED WITH ALGAE, AS FEED BINDERS IN COMPOUND FEEDS
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventor
Aksoy, Burak
Jiang, Zhihua
Aksoy, Mediha
Beck, Benjamin
Abstract
Animal feed binders made from defibrillated lignocellulosic fibers, animal feeds comprising the defibrillated lignocellulosic fibers, and methods to make animal feeds using the defibrillated lignocellulosic fibers.
In at least one illustrative embodiment, a cooling system includes a heat source, multiple electrocaloric material layers coupled to the heat source, and a heat sink coupled to the electrocaloric material layers. An electric field applied to each electrocaloric material layer is independently controllable. The electric field applied to each electrocaloric material layer is operable to move heat energy from the heat source to the heat sink during an interval, and to restore initial conditions of the electrocaloric material layers during a subsequent interval. The heat sink, the electrocaloric material layers, and the heat source may be bonded together. The electrocaloric material layers and the heat source may be bonded together, and the heat sink may be removably coupled to the electrocaloric material layers. Other embodiments are described and claimed.
The present tree seedling inventory system includes both a mobile platform used to obtain images of seedlings and a tree seedling inventory system to count the seedlings. A recurrent neural network can receive processed imaging data and utilize a model to accurately count the seedlings as the mobile platform passes along a seedling bed. The system may also provide additional accurate seedling quality data about the seedlings, such as shoot height, root collar diameter, and needle coloration.
Provided is an apparatus for supporting an equipment manufacturing process, the apparatus including: a display; and a processor providing a user with a graphical user interface (GUI) for supporting a target-equipment manufacturing process of the user in the form of mixed reality (MR) through the display, and supporting an interaction operation between the GUI and a user action.
G09B 5/02 - Electrically-operated educational appliances with visual presentation of the material to be studied, e.g. using film strip
G06F 3/04815 - Interaction with a metaphor-based environment or interaction object displayed as three-dimensional, e.g. changing the user viewpoint with respect to the environment or object
G06F 3/04842 - Selection of displayed objects or displayed text elements
29.
METHOD TO DELIVER CHEMICALS AND NUCLEIC ACIDS TO PLANT CELLS USING CELLULOSE NANOCRYSTALS AS A CARRIER
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (USA)
AUBURN UNIVERSITY (USA)
Inventor
Khodakovskaya, Mariya
Davis, Virginia
Clouse, Delaney
Vinzant, Kari
Abstract
A nanomaterial conjugate for delivering an active agent to a plant comprising a nanocarrier and an active agent linked to the nanocarrier. The nanocarrier is cellulose nanocrystal (CNC), and the nanocarrier delivers the active agent across cell walls of cells of the plant.
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
A01N 25/24 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
A01N 37/38 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio-anal having at least one oxygen or sulfur atom attached to an aromatic ring system
30.
HIGH ENTROPY OXIDES AND METHODS OF SYNTHESIS AND USE THEREOF
The present invention provides compositions of compounds comprising a metal M and a macrocyclic ligand represented by General Formula I, and contrast agents comprising the compositions thereof. In various embodiments, the present invention also relates to methods of enhancing methods of enhancing magnetic resonance imaging (MRI) in a living subject, the method comprising administering to a subject an effective amount of a contrast agent comprising a solution or suspension of the composition thereof.
Disclosed are compositions comprising rLS/ArkSe.GMCSF and a live attenuated IBV vaccine, and methods of using the same for inducing an immune response against IBV or vaccinating against IBV.
Described herein DNA-based assays that include nanostructures providing a simple, highly sensitive method for small molecule, biologic and peptide measurements that are optimized for use in a commercial, point-of-care diagnostic settings and systems. These DNA-based assays may include a combination of multiple redox molecules (e.g., methylene blue) such as between 3-8 redox molecules, and a spacer of between about 2 A and 20 A (and in particular between 3 A and 8 A), that results in an assay that has significantly greater signal and greater sensitivity as compared to prior DNA-based assays.
Technologies for platooned include a leader vehicle and one or more follower vehicles each including a computing device. The leader vehicle computing device controls velocity of the leader vehicle within a predetermined route based on a grade profile of the predetermined route. The leader vehicle may perform nonlinear model predictive control using a cost function based on predicted velocity error and predicted fuel consumption. The follower vehicle computing device controls velocity of the follower vehicle within the predetermined route based on headway distance to the leader vehicle and the grade profile. The follower vehicle may perform nonlinear model predictive control using a cost function based on predicted headway error, predicted headway rate of change, and predicted fuel consumption. Other embodiments are described and claimed.
B60W 40/12 - Estimation or calculation of driving parameters for road vehicle drive control systems not related to the control of a particular sub-unit related to parameters of the vehicle itself
35.
PHAGE-PEPTIDE CONSTRUCTS FOR STIMULATION OF AN ANTI-CANCER IMMUNE RESPONSE AGAINST CD47
Edward Via College of Osteopathic Medicine - Auburn (USA)
Inventor
Samoylova, Tatiana I.
Samoylov, Alexandre M.
Brock, Kenny V.
Cochran, Anna M.
Gillespie, James W.
Abstract
Disclosed are recombinant bacteriophage constructs and related exogenous peptide sequences for generating immune responses against CD47. The disclosed recombinant phage constructs bind to antibodies against CD47 and can be administered to an animal to generate an immune response against CD47, including generating anti-CD47 antibodies. The disclosed recombinant phage may comprise an amino acid sequence of CD47, epitopic fragments, variants, or functional mimics thereof. Also disclosed are methods for making and selecting such recombinant phage constructs and compositions that comprise such constructs (e.g., compositions for inducing an immune response against CD47 including pharmaceutical or veterinary compositions used as vaccines). Also disclosed are recombinant polynucleotides comprising genomic nucleic acid of the recombinant phage constructs disclosed herein.
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
Microorganisms and microbial production methods for the biosynthesis of ester compounds are provided. Useful examples employ microorganisms that have been genetically modified to express alcohol acyltransferases, either from other species or that have been modified to increase their activity in catalyzing the esterification of alcohols. Additional useful examples employ microorganisms that have been genetically modified to express lipases, either from other species or that have been modified to increase their activity in catalyzing the esterification of organic acids. Additional modifications are presented that significantly increase ester production.
Engineered wood products and binder compositions for cold-pressed applications are provided. Methods are also provided for formulating binders and producing the engineered wood products. The binder comprises a soy product and an adhesive formulation. The binders are prepared by mixing the soy product with the adhesive formulation prior to application to a lignocellulosic material to form the engineered wood. The present compositions and methods provide enhanced bonding and shorter holding time at decreased cost.
Engineered wood products and binder compositions for cold-pressed applications are provided. Methods are also provided for formulating binders and producing the engineered wood products. The binder comprises a soy product and an adhesive formulation. The binders are prepared by mixing the soy product with the adhesive formulation prior to application to a lignocellulosic rnaterial to forrn the engineered wood. The present cornpositions and rnethods provide enhanced bonding and shorter holding tirne at decreased cost.
B32B 21/04 - Layered products essentially comprising wood, e.g. wood board, veneer, wood particle board comprising wood as the main or only constituent of a layer, next to another layer of a specific substance
B32B 37/12 - Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by using adhesives
C09J 201/00 - Adhesives based on unspecified macromolecular compounds
39.
ASSAY METHOD FOR POINT OF CARE QUANTIFICATION OF AN IMMUNOPHILIN-BINDING IMMUNOSUPPRESSANT DRUG
Methods and apparatuses, including assays, for detection and/or quantification of tacrolimus that utilize nucleic acid-based nanostructures linked to tacrolimus. In particular, described herein are biosensors having a sensing mechanism configured to react to a tacrolimus-specific binding agent, such as an aptamer or antibody that binds tacrolimus. In some variations, these methods and apparatuses may be configured to provide an electrochemical read-out in which the nucleic acid-based nanostructure is operated in conjunction with a tacrolimus-specific binding agent for sample quantification. A biosensor or a set of biosensors as described herein can be used as a standalone measurement system for tacrolimus and/or as part of a multiplexed cartridge for multiple analytes.
The present disclosure provides fibrous composition comprising a soluble or a dispersible N-halamine, for example 1-chloro-2,2,5,5-tetramethyl-4-imidazolidinone (i.e., compound I). Additionally, the disclosure provides methods for producing the fibrous compositions comprising a soluble or a dispersible N-halamine as well as methods for protecting a person from an infection using the fibrous compositions comprising a soluble or a dispersible N-halamine. The compositions and methods according to the present disclosure provide several advantages, such as stability, less time to provide sufficient antimicrobial inactivation, and are inexpensive and require lower amount of active concentrations to be effective.
The present tree seedling inventory system includes both a mobile platform used to obtain images of seedlings and a tree seedling inventory system to count the seedlings. A recurrent neural network can receive processed imaging data and utilize a model to accurately count the seedlings as the mobile platform passes along a seedling bed. The system may also provide additional accurate seedling quality data about the seedlings, such as shoot height, root collar diameter, and needle coloration.
G06V 10/147 - Optical characteristics of the device performing the acquisition or on the illumination arrangements - Details of sensors, e.g. sensor lenses
G06V 10/80 - Fusion, i.e. combining data from various sources at the sensor level, preprocessing level, feature extraction level or classification level
A novel bacteria strain Bacillus velezensis ABN1001 was deposited at the International Depositary Authority of Canada. The bacteria, or mutants thereof, or metabolites produced by the bacteria, can be used in compositions for controlling plant disease, treating plant disease, and/or promoting plant growth.
Described herein are DNA-nanostructures that can be used in an assay to detect and/or quantify an analyte of interest. Aspects of the DNA-nanostructure can include a single DNA molecule composed of hairpin structural motifs, an anchor recognition moiety, and a signal moiety, where the anchor recognition moiety and the signal moiety are in effective proximity to each other such that the tethered diffusion of the signal molecule can be altered based upon binding status of the anchor recognition moiety. Also described herein are methods of making and using the DNA-nanostructures.
Provided is a method of treating a disease caused by a nidovirus that encodes Nsp15, such as a coronavirus, an arterivirus, or a torovirus, in a subject in need thereof comprising administering a therapeutically effective amount of an active agent selected from 3′-uridylic acid, 5′-uridylic acid, citrate, methacycline, meclocycline sulfosalicylate, mitoxantrone, epirubicin hydrochloride, daunorubicin hydrochloride, sorafenib, sunitinib malate, primaquine diphosphate, closantel, isopropyl ester of N4-hydroxycytidine, GpU dinucleotide or derivatives thereof, and tipiracil or N-substituted derivatives thereof. Further provided are a method of inhibiting an Nsp15 endoribonuclease of a nidovirus that encodes Nsp15 and compounds of formulas (I′) and (II′).
A61K 31/7072 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
A61K 31/7084 - Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
A61K 31/513 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
41 - Education, entertainment, sporting and cultural services
Goods & Services
caps being headwear; shirts; t-shirts Arranging and conducting athletic competitions, athletic events, athletic tournaments, and athletic exhibitions for entertainment purposes
The present disclosure describes system and methods for determining cardiac events from a physiological data signal and optionally constructing a Pressure-Volume (PV) loop display from non-simultaneously acquired measurements of pressure and volume data. One such method comprises obtaining, by a computing device, a physiological data signal of a heart of an individual; identifying, by the computing device, features of the physiological data signal and applying the features as inputs to a prediction model; determining, by the computing device using the prediction model, the cardiac events for one or more valves of the heart, wherein the cardiac events include timing of opening and closing of the one or more valves of the heart; and outputting, by the computing device, the cardiac events determined using the prediction model. The physiological data signal can be combined with non-simultaneously acquired volume data to create a PV loop display.
In at least one illustrative embodiment, an electromagnetic filter may include a transfer pipe and multiple electromagnetic filter elements positioned in an interior volume of the pipe. Each electromagnetic filter element includes a support comb, a solenoid coupled to the support comb, and multiple magnetic members arranged in a planar array positioned within an opening of the support comb. Each magnetic member may rotate about an end that is coupled to the support comb. The magnetic members may be magnetostrictive sensors and may include a biorecognition element to bind with a target microorganism. A method for fluid filtration includes coupling the electromagnetic filter between a fluid source and a fluid destination, energizing the solenoids of each electromagnetic filter elements, and flowing a fluid media through the transfer pipe of the electromagnetic filter. The fluid media may be liquid food such as fruit juice. Other embodiments are described and claimed.
G01N 29/22 - Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object - Details
B03C 1/034 - Component parts; Auxiliary operations characterised by the magnetic circuit characterised by the matrix elements
A23L 3/00 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
A23L 3/26 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by irradiation without heating
B01D 35/06 - Filters making use of electricity or magnetism
C02F 1/48 - Treatment of water, waste water, or sewage with magnetic or electric fields
41 - Education, entertainment, sporting and cultural services
43 - Food and drink services, temporary accommodation
Goods & Services
Private social club services, namely, arranging, organizing, and hosting social events, get-togethers, and parties for club members Bar services; restaurant services
The present disclosure provides a method of producing a lubricant composition comprising the steps of hydrolyzing a starting material to provide a hydrolyzed product mixture, reacting the hydrolyzed product mixture under conditions capable of producing a condensation product mixture, contacting the condensation product mixture with a cyclic compound to provide a coupled product mixture, and hydrogenating the coupled product mixture to provide the lubricant composition. In addition, other methods and compositions thereof are also provided.
A method for manufacturing individualized protective gear such as pads based on a scan, and the resulting pads, are disclosed herein. A garment comprising a pocket with a visibly defined border is selected. A wearer dons the garment. A scan is taken of at least a portion of the garment over the wearer's body at the location where the pocket is disposed over the wearer's body. The scan is converted to a mesh model. The mesh model is used to define a first surface of the equipment configured to form to the wearer's body at the location where the pocket is disposed over the wearer's body and a second surface offset from the first surface. The model may be checked to identify production defects, which, if present, are removed. The equipment may be manufactured using additive printing technology.
A41H 43/00 - Other methods, machines, or appliances
A41D 13/015 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches with shock-absorbing means
A41D 13/05 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
A41H 1/02 - Devices for taking measurements on the human body
A41H 1/06 - Measuring aids or methods in combination with marking
A41H 3/00 - Patterns for cutting-out; Methods of drafting or marking-out such patterns, e.g. on the cloth
A41H 3/04 - Making patterns by modelling on the human body
Methods of dewatering viscous materials are provided. The method comprises contacting the viscous material with pressurized carbon dioxide at a temperature and for a time wherein at least a fraction of water is expressed from the viscous material. Then the pressure is released, and the water expressed from the viscous material is removed to yield a dewatered product. Exemplary viscous materials that can be dewatered by the method include black liquor from wood pulping operations, wet lignin, wet super water absorbent polymers and sugar solutions. The pressurized carbon dioxide is present in subcritical or supercritical form. The method provides dewatering at reduced cost.
MEMS-based sensors can experience undesirable signal frequencies caused by vibrations, shocks, and accelerations, among other phenomena. A microisolation system can isolate individual MEMS-based sensors from undesirable signal frequencies and shocks. An embodiment of a system for microisolation of a MEMS-based sensor can include an isolation platform connected to one or more folded springs. Another embodiment of a system for microisolation can include an isolation platform and/or a frame connected to a mesh damping mechanism. In at least one embodiment, a mesh damping mechanism can be a microfibrous metal mesh damper. In one or more embodiments, a system for microisolation can include an isolation platform connected to one or more L-shaped springs, and a thickness of the one or more L-shaped springs can be less than a thickness of the isolation platform.
B81B 7/02 - Microstructural systems containing distinct electrical or optical devices of particular relevance for their function, e.g. microelectro-mechanical systems (MEMS)
53.
DIROFILARIA VOLATILE ORGANIC COMPOUND SIGNATURES AND USES THEREOF
Described herein are Dirofilarial exhalant signatures and methods of detecting a Dirofilaria signature in a non-blood biological sample, such as exhalant, that can be used to detect Dirofilarial infection in a subject, such as a canine.
G01N 1/22 - Devices for withdrawing samples in the gaseous state
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
A61K 31/555 - Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
A pharmaceutical composition comprises a metal nanoparticle having an average diameter of about 0.5 nm to about 5 nm. The composition may be used to treat cancer or an anosmia-related disease.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/60 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
The present disclosure provides a method of producing a lubricant composition comprising the steps of hydrolyzing a starting material to provide a hydrolyzed product mixture, reacting the hydrolyzed product mixture under conditions capable of producing a condensation product mixture, contacting the condensation product mixture with a cyclic compound to provide a coupled product mixture, and hydrogenating the coupled product mixture to provide the lubricant composition. In addition, other methods and compositions thereof are also provided.
C10M 169/04 - Mixtures of base-materials and additives
C10M 175/00 - Working-up used lubricants to recover useful products
C10M 177/00 - Special methods of preparation of lubricating compositions; Chemical modification by after-treatment of components or of the whole of a lubricating composition, not covered by other classes
Described herein are nucleic acid-based electrochemical proximity assays (ECPAs) for sample quantification. The invention may also include a biosensor with a sensing mechanism that uses a pair of aptamers or antibodies that bind the target of interest. More specifically, the invention relates to an electrochemical-based read out of a sensing mechanism that uses a nucleic acid-based proximity assay in conjunction with a pair of aptamers or antibodies for sample quantification. The biosensor or a set of biosensors can be used either as a standalone measurement system for a single analyte target or as a component of a multiplexed cartridge for multiple analytes.
The present disclosure relates to structures and methods of use of textiles for protection, and more particularly, relates to single layer knitted structures that can be worn as garments to block mosquito bites. The knit structures of the present embodiments can include single layer structures having a unique geometric combination of yarn properties and textiles to block mosquito bites in a single, comfortable layer of fabric. The knit structures can include one or more controllable parameters that can be adjusted to increase and/or decrease the bite blocking ability of the knit structure.
A01M 29/34 - Scaring or repelling devices, e.g. bird-scaring apparatus preventing or obstructing access or passage, e.g. by means of barriers, spikes, cords, obstacles or sprinkled water specially adapted for insects
A01M 29/30 - Scaring or repelling devices, e.g. bird-scaring apparatus preventing or obstructing access or passage, e.g. by means of barriers, spikes, cords, obstacles or sprinkled water
D04B 1/00 - Weft knitting processes for the production of fabrics or articles not dependent on the use of particular machines; Fabrics or articles defined by such processes
D04B 1/24 - Weft knitting processes for the production of fabrics or articles not dependent on the use of particular machines; Fabrics or articles defined by such processes specially adapted for knitting goods of particular configuration wearing apparel
D04B 1/14 - Other fabrics or articles characterised primarily by the use of particular thread materials
41 - Education, entertainment, sporting and cultural services
Goods & Services
Educational services, namely, providing academic support through arranging and conducting academic and professional workshops in the field of engineering, arranging and conducting educational study groups in the field of engineering, and individual career counseling, namely, providing advice concerning education options to pursue career opportunities in the field of engineering, all of the above for demographic groups that are underrepresented in the field of engineering
59.
VISION INSPECTION SYSTEM BASED ON DEEP LEARNING AND VISION INSPECTING METHOD THEREOF
The present disclosure relates to a vision inspection system based on deep learning and a vision inspection method of. The vision inspection system based on deep learning according to the present disclosure includes a GT generation module that generates a GT for a region of interest of a car part image, a learning module that receives learning data from the GT generation module, performs learning based on deep learning, and outputs a weight file, and an interface module that detects a defect with respect to an image file received from a vision program by using the weight file, and returns a defect detection result to the vision program.
The present invention relates to the production of cell cultures and tissues from undifferentiated pluripotent stem cells using three-dimensional biomimetic materials. The resultant cell cultures or tissues can be used in any of a number of protocols including testing chemicals, compounds, and drugs. Further, the methods and compositions of the present invention further provide viable cell sources and novel cell delivery platforms that allow for replacement of diseased tissue and engraftment of new cardiomyocytes from a readily available in vitro source. The present invention includes novel methods required for the successful production of cell cultures and tissues, systems and components used for the same, and methods of using the resultant cell and tissue compositions.
A method for manufacturing individualized protective gear such as pads based on a scan, and the resulting pads, are disclosed herein. A garment comprising a pocket with a visibly defined border is selected. A wearer dons the garment. A scan is taken of at least a portion of the garment over the wearer's body at the location where the pocket is disposed over the wearer's body. The scan is converted to a mesh model. The mesh model is used to define a first surface of the equipment configured to form to the wearer's body at the location where the pocket is disposed over the wearer's body and a second surface offset from the first surface. The model may be checked to identify production defects, which, if present, are removed. The equipment may be manufactured using additive printing technology.
EDWARD VIA VIRGINIA COLLEGE OF OSTEOPATHIC MEDICINE (USA)
Inventor
Castellano, Vitale Kyle
Zabala, Michael
Burch, Thomas E.
Burch, Hayden
Commander, Jonathan
Brock, Kenny V.
Abstract
Disclosed herein is a device for repeatably and accurately measuring the threshold sensitivity of the skin on a body part or surface such as the plantar surface of the foot. The machine uses a monofilament pressure test, where a monofilament is applied to the surface of the skin until it buckles at a corresponding force. The device may measure a broad range of pressures and responsive sensation in the patient using multiple applications of the monofilament. The patient indicates a positive or negative response, based on whether the patient sensed the monofilament pressure. The machine may include a foot clamping assembly, a support chassis, a linear motion translation assembly for locating the monofilament at a given position for testing, and a camera for taking images used to identify testing locations and report results. Methods of use and testing protocols are also described herein.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventor
Toro Guzman, Haroldo, E.
Yu, Qingzhong
Abstract
Disclosed are recombinant Newcastle disease virus (rNDV) vectors, related polynucleotides, and methods for eliciting an immune response against avian infectious bronchitis virus (IBV) or vaccinating against IBV. In particular, the recombinant proteins, compositions, vectors, kits, and methods may be utilized to immunize poultry against disease associated with IBV infection or to protect poultry from IBV infection.
Descried in certain example embodiments herein are engineered fish, particularly engineered catfish, that are engineered to contain modified myostatin, melanocortin-4 receptor, and/or one or more n-3 fatty acid biosynthesis pathway genes and/or gene products.
Therapeutic or prophylactic compositions providing an active agent, such as an antigen or a vector that contains and expresses an antigen, encapsulated in or incorporated into a biodegradable polymeric particle are provided. The compositions can also provide an active agent that is not encapsulated in or incorporated into the biodegradable polymeric particle in order to provide an initial or prime delivery of the active agent. Particles or composites providing an active agent encapsulated by a first and second polymer are also provided, wherein polymers are distributed in a gradient from a core of the composite to a surface of the composite, and configured to provide a delayed release of the active agent by a period of 7 days to 6 months. Methods of producing composites are also provided. Pharmaceutical formulations providing a single dose composition are also provided, along with methods for administering the pharmaceutical compositions to a subject in need thereof a therapeutically effective amount of an active agent are provided.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventor
Chin, Bryan A.
Torbert, Iii, Henry Allen
Yakubova, Galina N.
Kavetskiy, Aleksandr
Sargsyan, Nikolay
Abstract
A system for analyzing soil content of a field includes a data acquisition unit configured to detect gamma spectra of each of a plurality of soil samples, wherein a surface area of the field is divided into a plurality of portions and the plurality of soil samples comprises at least one soil sample from each of the plurality of portions, a navigation unit configured to detect geographic coordinates of each of the plurality of soil samples, a data analysis unit configured to associate the detected gamma spectra of each of the plurality of soil samples with the geographic coordinates of the soil sample and determine a weight percent of at least one element within each of the soil samples based on the detected gamma spectra, and an element content map unit configured to generate a map indicating concentration of the at least one element within the soil of the field.
G01N 23/221 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by activation analysis
G01N 23/22 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material
G01N 23/222 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by activation analysis using neutron activation analysis [NAA]
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01V 5/02 - Prospecting or detecting by the use of nuclear radiation, e.g. of natural or induced radioactivity specially adapted for surface logging, e.g. from aircraft
G01V 5/22 - Active interrogation, i.e. by irradiating objects or goods using external radiation sources, e.g. using gamma rays or cosmic rays
67.
A BACILLUS STRAIN AND METHODS OF ITS USE FOR PLANT GROWTH PROMOTION
The present invention relates to a composition comprising a biologically pure culture of Bacillus spp. strain NRRL B-67746 and mutants of that strain having all the identifying characteristics of the strain. The present invention also provides a method of promoting plant growth, wherein the method comprises applying such strain or mutants to the plant, to a part of the plant and/or to a locus of the plant.
The invention relates to an HVAC apparatus, method, and system. Aspects of the invention include a supplemental heat source with an air handler unit for a conventional forced air heating and cooling system. The supplemental heat source in one example is a hydronic subsystem. It can be used alone or to supplement the forced air subsystem. Another aspect of the invention includes an air handling subsystem that has a housing that can be highly flexible in configuration and installation. The housing can support internal components, including a hydronic or other supplemental heat source with the forced air components. At least two sides of the housing can be configured for access for maintenance and repair. A control system can be designed to eliminate need for defrost cycle for forced air refrigeration-type subsystem and/or for better maintenance for comfort in the air conditioned space.
F24F 5/00 - Air-conditioning systems or apparatus not covered by group or
F24D 12/02 - Other central heating systems having more than one heat source
F24D 19/10 - Arrangement or mounting of control or safety devices
69.
APPARATUS AND PROCESS FOR TREATING BIOMASS FOR ON-SITE PRODUCTION OF CELLULOLYTIC ENZYMES AND METHOD OF USING THE ENZYMES TO MANUFACTURE FUELS AND CHEMICALS
An integrated process and corresponding apparatus that produces a relatively clean, delignified cellulose product from lignocellulosic biomass. The method includes treating a portion of the delignified cellulose itself as a substrate to produce on-site cellulolytic enzymes, including further treating the remaining delignified cellulose with the resulting cellulolytic enzymes for in situ enzymatic hydrolysis. The process and apparatus are useful to produce fermentable sugars for cost-effective manufacturing of fermentable sugars, fuels, bioproducts and chemicals.
Apparatus and process for treating biomass for on-site production of cellulolytic enzymes and method of using the enzymes to manufacture fuels and chemicals
An integrated process and corresponding apparatus that produces a relatively clean, delignified cellulose product from lignocellulosic biomass. The method includes treating a portion of the delignified cellulose itself as a substrate to produce on-site cellulolytic enzymes, including further treating the remaining delignified cellulose with the resulting cellulolytic enzymes for in situ enzymatic hydrolysis. The process and apparatus are useful to produce fermentable sugars for cost-effective manufacturing of fermentable sugars, fuels, bioproducts and chemicals.
C12P 19/14 - Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase, e.g. by alpha-amylase
C08B 37/00 - Preparation of polysaccharides not provided for in groups ; Derivatives thereof
C13K 13/00 - Sugars not otherwise provided for in this class
C08H 8/00 - Macromolecular compounds derived from lignocellulosic materials
71.
APPARATUS AND PROCESS FOR TREATING BIOMASS FOR ON-SITE PRODUCTION OF CELLULOLYTIC ENZYMES AND METHOD OF USING THE ENZYMES TO MANUFACTURE FUELS AND CHEMICALS
in situin situ enzymatic hydrolysis. The process and apparatus are useful to produce fermentable sugars for cost-effective manufacturing of fermentable sugars, fuels, bioproducts and chemicals.
Disclosed herein is a device for repeatably and accurately measuring the threshold sensitivity of the skin on a body part or surface such as the plantar surface of the foot. The machine uses a monofilament pressure test, where a monofilament is applied to the surface of the skin until it buckles at a corresponding force. The device may measure a broad range of pressures and responsive sensation in the patient using multiple applications of the monofilament. The patient indicates a positive or negative response, based on whether the patient sensed the monofilament pressure. The machine may include a foot clamping assembly, a support chassis, a linear motion translation assembly for locating the monofilament at a given position for testing, and a camera for taking images used to identify testing locations and report results. Methods of use and testing protocols are also described herein.
A medical backpack for storing medical supplies and medical equipment is disclosed. The medical backpack can be used by medics working in rural or remote areas that are not accessible by car and where access to hospitals and medical supplies is limited or non-existent. The medical backpack is light enough to carry long distances and comprised of a number of different compartments that are flexible to equip with various supplies for specific needs and circumstances.
45 - Legal and security services; personal services for individuals.
Goods & Services
Live animals, namely, dogs Providing security screening services in the nature of dog detection services, namely, providing dogs that detect explosives and contraband for the protection of property and individuals
A medical backpack for storing medical supplies and medical equipment is disclosed. The medical backpack can be used by medics working in rural or remote areas that are not accessible by car and where access to hospitals and medical supplies is limited or non-existent. The medical backpack is light enough to carry long distances and comprised of a number of different compartments that are flexible to equip with various supplies for specific needs and circumstances.
A45F 3/04 - Sacks or packs carried on the body by means of two straps passing over the two shoulders
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
A45F 3/00 - Travelling or camp articles; Sacks or packs carried on the body
Culture systems and methods of using same. The systems include a housing defining an inner space. The inner space includes a headspace and at least a portion of a reservoir. A surface for immobilizing cells is moveable between the headspace and the reservoir. The systems can be used for coculturing methanotrophs and phototrophs for processing biogas and wastewater, particularly from anaerobic digesters.
An air conditioning device includes an inlet plenum to receive input air, a sprayer to charge at least one of a plurality of liquid droplets generating at least one charged liquid droplet and to release the charged liquid droplet into air rotating vortex, moving the input air within a spray chamber, to cause the charged liquid droplet to attract and attach a vapor molecule of the input air separating the molecule from the input air, a separation chamber to cause the liquid droplet with the attached vapor molecule to separate from the vortex to condense and collect as liquid, and an air outlet to direct, away from the air conditioning device, output air including air remaining following the separation, from the vortex, of the liquid droplet with the attached vapor molecule, where a first humidity of the output air is less than a second humidity of the input air.
B01D 53/30 - Controlling by gas-analysis apparatus
B01D 45/16 - Separating dispersed particles from gases or vapours by gravity, inertia, or centrifugal forces by centrifugal forces generated by the winding course of the gas stream
B01D 53/32 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by electrical effects other than those provided for in group
B04C 5/103 - Bodies or members, e.g. bulkheads, guides, in the vortex chamber
B04C 9/00 - Combinations with other devices, e.g. fans
F24F 3/14 - Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by dehumidification
78.
TECHNOLOGIES FOR MICROELECTROMECHANICAL SYSTEMS WITH COMPOSABLE PIEZOELECTRIC ACTUATORS
In at least one illustrative embodiment, a microelectromechanical system (MEMS) includes a composable piezoelectric actuator electrically coupled to a terminal. In response to a voltage applied across electrodes of the actuator, a piezoelectric rod moves from an initial position to a displaced position. In an embodiment, the MEMS includes two terminals, a resistive element is coupled between the terminals, and when in the displaced position the rod contacts one of the terminals. In an embodiment, the MEMS includes three terminals, and when a threshold voltage is applied to one of the terminals, the rod moves to the displaced position and allows current to flow between the other two terminals. In an embodiment, the MEMS includes a primary set of actuators that are mechanically but not electrically connected to a secondary set of actuators. An output terminal is coupled to the second set of actuators. Other embodiments are described and claimed.
In at least one illustrative embodiment, a microelectromechanical system (MEMS) includes a composable piezoelectric actuator electrically coupled to a terminal. In response to a voltage applied across electrodes of the actuator, a piezoelectric rod moves from an initial position to a displaced position. In an embodiment, the MEMS includes two terminals, a resistive element is coupled between the terminals, and when in the displaced position the rod contacts one of the terminals. In an embodiment, the MEMS includes three terminals, and when a threshold voltage is applied to one of the terminals, the rod moves to the displaced position and allows current to flow between the other two terminals. In an embodiment, the MEMS includes a primary set of actuators that are mechanically but not electrically connected to a secondary set of actuators. An output terminal is coupled to the second set of actuators. Other embodiments are described and claimed.
H01L 41/09 - Piezo-electric or electrostrictive elements with electrical input and mechanical output
H01L 41/04 - SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR - Details thereof - Details of piezo-electric or electrostrictive elements
Described herein are Dirofilarial exhalant signatures and methods of detecting a Dirofilaria signature in a non-blood biological sample, such as exhalant, that can be used to detect Dirofilarial infection in a subject, such as a canine.
A61K 31/555 - Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
G01N 1/22 - Devices for withdrawing samples in the gaseous state
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
The present disclosure provides a means to remove oxidative compounds such as free halogen and chloramines from a liquid, while also providing components with antimicrobial properties in order to combat biofouling and the shedding of pathogens into liquids. In particular, methods of removing an oxidative compound from a liquid in which the liquid is contacted with one or more polymeric beads. As described herein, the oxidative compound binds to the polymeric bead and is removed from the liquid.
B01J 20/28 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
The present disclosure provides a means to remove oxidative compounds such as free halogen and chloramines from a liquid, while also providing components with antimicrobial properties in order to combat biofouling and the shedding of pathogens into liquids. In particular, methods of removing an oxidative compound from a liquid in which the liquid is contacted with one or more polymeric beads. As described herein, the oxidative compound binds to the polymeric bead and is removed from the liquid.
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
A metal 3D printer is disclosed for fabricating metal articles by depositing molten metal onto a print bed. The metal 3D printer has a print head having a crucible and nozzle. The crucible melts metal and the nozzle deposits the molten metal onto the print bed. The 3D printer further includes an induction heating system to heat the print head and a heated print bed disposed below the nozzle. The metal 3D printer also has a computer numerically controlled (CNC) gantry for moving the print head and the print bed relative to each other along X, Y, and Z axes. Shielding gas may be directed proximate to the crucible or the nozzle. The feedstock for the printer may be a plurality of wire strands braided together. A mesh overlay may be positioned on top of the print bed.
B29C 64/118 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
B33Y 30/00 - ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING - Details thereof or accessories therefor
B33Y 70/00 - Materials specially adapted for additive manufacturing
H05B 6/06 - Control, e.g. of temperature, of power
A metal 3D printer is disclosed for fabricating metal articles by depositing molten metal onto a print bed. The metal 3D printer has a print head formed of a crucible and a nozzle. The crucible heats the molten metal and the nozzle deposits the molten metal onto the print bed. The 3D printer further includes an induction heating system to heat the print head and a heated print bed disposed below the nozzle. The metal 3D printer also comprises a computer numerically controlled (CNC) gantry configured to move the print head and the print bed relative to each other along X, Y, and Z axes. A shielding gas blower may direct a first stream of shielding gas proximate to the crucible and a second stream of shielding gas proximate to the nozzle. The feedstock for the printer may comprise a plurality of wire strands braided together. A mesh overlay may be positioned on top of the print bed.
B22D 23/00 - Casting processes not provided for in groups
B33Y 30/00 - ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING - Details thereof or accessories therefor
88.
Two-dimensional-material-based field-effect transistor for detection of pathogens and methods for manufacturing
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two-dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
The devices, methods, and compositions disclosed herein accomplish robust cell encapsulation in polymer microparticles using a vertically oriented microfluidic device. A hydrophilic polymer precursor solution is flowed into a first inlet channel, which extends inward from an upper surface of the device housing. A hydrophobic fluid is flowed into a second inlet channel, which extends inward from a lower surface of the device housing. The two inlet channels meet at a junction, and an outlet channel extends away from the two inlet channels. When the two inwardly flowing streams meet at the junction, the polymer precursor solution disperses into the hydrophobic fluid. The dispersed precursor droplets are photopolymerized into microparticles as they travel through the outlet channel. The resulting microparticles are highly uniform, and are larger than conventionally formed microparticles. Cells of varying types can be encapsulated with high viability and spatial uniformity.
The present invention relates, in part, to novel compounds comprising 4-imidazolidinone-fused cyclic peptides and compositions thereof. The present invention also relates to methods of generating said compounds and compositions thereof as well as methods of inhibiting protein-protein interaction using said compounds or compositions thereof. In another aspect, the present invention relates, in part, to methods of treating or preventing a various diseases or disorders using said compounds or compositions thereof.
Described herein DNA-based assays that include nanostructures providing a simple, highly sensitive method for small molecule, biologic and peptide measurements that are optimized for use in a commercial, point-of-care diagnostic settings and systems. These DNA- based assays may include a combination of multiple redox molecules (e.g., methylene blue) such as between 3-8 redox molecules, and a spacer of between about 2A and 20 A (and in particular between 3A and 8A), that results in an assay that has significantly greater signal and greater sensitivity as compared to prior DNA-based assays.
Use of pectin or pectin-related saccharides to enhance efficacy of plant growth-promoting rhizobacteria (PGPR) strains for promoting growth and health in plants and animals
Disclosed are compositions and methods that include or utilize plant growth promoting rhizobacteria (PGPR) for improving growth and health in plants and animals. The compositions and methods include or utilize a plant growth promoting rhizobacteria (PGPR) that expresses a protein associated with pectin metabolism, and a saccharide comprising pectin or a pectin-related saccharide.
A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
A high-friction road patch may comprise an aggregate capable of providing sufficient friction between a road surface and vehicle wheel. In some embodiments, the patch may comprise a waterproof, asphalt overlay with a first layer of cured bitumen and calcined bauxite aggregate particles, a second layer of viscous bitumen and a reinforcement component, and a binder layer for bonding the overlay with the road surface. The resulting product may provide a sufficient skid resistance value in an overlay that is far less susceptible to or incapable of debonding as with prior art solutions.
E01C 23/10 - Devices or arrangements for working the finished surface; Devices for repairing the surface of damaged paving for introducing material into substructure
E01C 21/00 - Apparatus or processes for surface stabilisation for road building or like purposes, e.g. mixing borrowed aggregate with binder
E01C 23/06 - Devices or arrangements for working the finished surface; Devices for repairing the surface of damaged paving
E01C 5/12 - Pavings made of prefabricated single units made of units with bituminous binders
A high-friction road patch may comprise an aggregate capable of providing sufficient friction between a road surface and vehicle wheel. In some embodiments, the patch may comprise a waterproof, asphalt overlay with a first layer of cured bitumen and calcined bauxite aggregate particles, a second layer of viscous bitumen and a reinforcement component, and a binder layer for bonding the overlay with the road surface. The resulting product may provide a sufficient skid resistance value in an overlay that is far less susceptible to or incapable of debonding as with prior art solutions.
The present technology provides a nanopore electrode sequencer for the characterization and sequencing of biomolecules. Two or more ultrathin MXene sheets containing nanopores serve as electrodes that bind and store cations which can be released to provide ionic current through the nanopore during sequencing, thereby eliminating access resistance to ions at the entrance to the nanopore from bulk solution. Resolution of ionic current changes caused by biopolymer components within the nanopore is thereby substantially improved, providing more sensitive and robust sequencing of biopolymers.
ABN1001ABN1001 was deposited at the International Depositary Authority of Canada. The bacteria, or mutants thereof, or metabolites produced by the bacteria, can be used in compositions for controlling plant disease, treating plant disease, and/or promoting plant growth.
A novel bacteria strain Bacillus velezensis ABN1001 was deposited at the International Depositary Authority of Canada. The bacteria, or mutants thereof, or metabolites produced by the bacteria, can be used in compositions for controlling plant disease, treating plant disease, and/or promoting plant growth.
Nanocomposite materials include a nanosheet containing a metal chalcogenide having a formula MXaYbZc and a carbonaceous substrate supporting the nanosheet. Methods for producing and using the nanocomposite materials are described.
C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound
99.
SERVICEABLE RESPIRATOR SYSTEM WITH CONFIGURABLE COMPONENTS
There is provided a respirator for supplying clean air for a wearer. The respirator comprises a face assembly comprising an oronasal mask configured to seal against and cover a nose region and a mouth region of the wearer. The face assembly may be configured to be interchangeable on the respirator between a half-face assembly and a full-face assembly. The respirator comprises a securing headgear releasably securable with the face assembly, the securing headgear assembly configured to secure the respirator on a head of the wearer. The respirator comprises a facepiece assembly for supplying the wearer with air for inhaling and releasing air exhaled by the wear, the facepiece assembly releasably securable with the face assembly. One or more of the face assembly, the facepiece assembly, or the securing headgear are configured to be released from the respirator, sterilized, and releasably resecured with the respirator.
C25B 11/075 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound
