A sensor-enabled pathogen identification, differentiation, and quantification system that integrates into supply chains in an end-to-end fashion and is built on a multi-source, multi-sectoral data environment. The system uses portable sensing platforms that are easily integrated at multiple points along a supply chain and which integrate sample analysis and data processing such that all necessary work can be performed on-site and/or via wireless data transfer.
G01N 33/483 - Analyse physique de matériau biologique
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Computer hardware and computer peripheral devices; Downloadable software in the nature of a mobile application for collecting, monitoring, testing, analyzing, detecting, organizing, managing, and reporting of biological, chemical, biochemical, and radiological threats in water, air, soil, surfaces, food, plants, animals, and humans; Recorded software for collecting, monitoring, testing, analyzing, detecting, organizing, managing, and reporting of biological, chemical, biochemical, and radiological threats in water, air, soil, surfaces, food, plants, animals, and humans; Downloadable software in the nature of a mobile application for for collecting, monitoring, testing, analyzing, detecting, organizing, managing, and reporting data in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; Recorded software for collecting, monitoring, testing, analyzing, detecting, organizing, managing, and reporting data in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; Downloadable software in the nature of a mobile application for data collection, analysis, and reporting in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; Recorded software for data collection, analysis, and reporting in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; Downloadable software in the nature of a mobile application for managing, organizing, displaying, tagging, bookmarking, storing, sharing or otherwise providing electronic media or information and data in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; Recorded software for for managing, organizing, displaying, tagging, bookmarking, storing, sharing or otherwise providing electronic media or information and data in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures scientific and technological research and development in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; consultation services in the fields of biological, chemical, biochemical, and radiological agents, and threats associated with same, analysis of biological, chemical, biochemical, and radiological threats and countermeasures; scientific and technological services, namely, testing services for others in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; scientific and technological services, namely, the monitoring, testing, detection, and management of biological, chemical, biochemical, and radiological threats in water, air, soil, surfaces, food, plants, animals, and humans; scientific and technological services, namely, biosecurity surveillance for water, air, soil, surfaces, food, plants, animals, and humans; scientific laboratory services; biological, chemical, biochemical, and radiological threat detection, testing, analysis, and management services; monitoring and testing of biological, chemical, biochemical, and radiological threats in water, air, soil, surfaces, food, plants, animals, and humans; providing scientific and technological information in the fields of biosecurity, biosurveillance, bioinformatics, biointelligence, biological, chemical, biochemical, and radiological; scientific and technological services, namely, data collection, analysis, and reporting in the fields of biosecurity, biosurveillance, bioinformatics, and biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; providing online non-downloadable software for managing, organizing, displaying, tagging, bookmarking, storing, sharing or otherwise providing electronic media or information and data in the fields of biosecurity, biosurveillance, bioinformatics, and biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; providing bioinformatics computational analysis of biological, chemical, biochemical, and radiological data sets, statistical data analysis, method validation and testing, data tracking and trending, and design of statistical sampling strategies including for a variety of threat-monitoring and technology development programs; providing research and consulting services for enhancing global health, safety, security, and to counter biological threats and countermeasures; providing laboratory research services in the field of biological, chemical, biochemical, and radiological detection systems, biological, chemical, biochemical, and radiological threat agents, and biological, chemical, biochemical, and radiological threat agent countermeasures; engineering and manufacturing services, namely, biological, chemical, biochemical, and radiological threat detection, management, and countermeasure devices and hardware and software systems; consulting services in the field of security risk assessment, namely, foreign materiel capture, assessment, biosecurity, and biosafety; consulting services in the field of collection of evidence for forensic purposes, namely, collection, analysis, testing, and reporting; consulting services for others in the fields of biosecurity, biosurveillance, bioinformatics, and biointelligence, biological, chemical, biochemical, and radiological threats and countermeasures; consulting services for others in the fields of design, planning, and implementation project management of biosecurity initiatives related to the monitoring, testing, and detection of biological, chemical, biochemical, and radiological threats in water, air, soil, surfaces, food, plants, animals, and humans; scientific and technological research and development in the fields of food production, food safety, public health, the environment, forestry, aquatic systems, and national security and defense, and law enforcement
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Animal feed; Seeds for agricultural purposes; Seeds for horticultural purposes; Hay; Raw vegetables; Live plants Anthelmintics; Veterinary preparations for livestock deworming; Animal feed additives for use as nutritional supplements for medical purposes
5.
METAL ADDITIVE MANUFACTURING APPARATUS AND METHODS
A metal 3D printer is disclosed for fabricating metal articles by depositing molten metal onto a print bed. The metal 3D printer has a print head formed of a crucible and a nozzle. The crucible heats the molten metal and the nozzle deposits the molten metal onto the print bed. The 3D printer further includes an induction heating system to heat the print head and a heated print bed disposed below the nozzle. The metal 3D printer also comprises a computer numerically controlled (CNC) gantry configured to move the print head and the print bed relative to each other along X, Y, and Z axes. A shielding gas blower may direct a first stream of shielding gas proximate to the crucible and a second stream of shielding gas proximate to the nozzle. The feedstock for the printer may comprise a plurality of wire strands braided together. A mesh overlay may be positioned on top of the print bed.
B22D 23/00 - Procédés de coulée non prévus dans les groupes
B22F 12/50 - Moyens d’alimentation en matériau, p. ex. têtes
B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
6.
USE OF PECTIN OR PECTIN-RELATED SACCHARIDES TO ENHANCE EFFICACY OF PLANT GROWTH-PROMOTING RHIZOBACTERIA (PGPR) STRAINS FOR PROMOTING GROWTH AND HEALTH IN PLANTS AND ANIMALS
To understand the growth-promoting and disease-inhibiting activities of plant growth-promoting rhizobacteria (PGPR) strains, the genomes of 12 Bacillus subtilis group strains with PGPR activity were sequenced and analyzed. These B. subtilis strains exhibited high genomic diversity, whereas the genomes of B. amyloliquefaciens strains (a member of the B. subtilis group) are highly conserved. A pairwise BLASTp matrix revealed that gene family similarity among Bacillus genomes ranges from 32-90%, with 2,839 genes within the core genome of B. amyloliquefaciens subsp. plantarum (now B. velezensis). Comparative genomic analyses of B. amyloliquefaciens strains identified genes that are linked with biological control and colonization of roots and/or leaves, including 73 genes uniquely associated with subsp. plantarum (now B. velezensis) strains that have predicted functions related to signaling, transportation, secondary metabolite production, and carbon source utilization. Although B. amyloliquefaciens (now B. velezensis) strains contain gene clusters that encode many different secondary metabolites, only polyketide biosynthetic clusters that encode difficidin and macrolactin are conserved within this subspecies. To evaluate their role in plant pathogen biocontrol, genes involved in secondary metabolite biosynthesis were deleted in B. amyloliquefaciens (now B. velezensis) strain, revealing that difficidin expression is critical in reducing the severity of disease, caused by Xanthomonas axonopodis pv. vesicatoria in tomato plants. This Example defines genomic features of PGPR strains and links them with biocontrol activity and with host colonization.
A01H 3/00 - Procédés de modification des phénotypes
A23K 10/18 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires de micro-organismes vivants
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p. ex. pour les poissons, les crustacés ou les mollusques
A61K 31/7004 - Monosaccharides ayant uniquement des atomes de carbone, d'hydrogène et d'oxygène
A61K 35/742 - Bactéries sporulées, p. ex. Bacillus coagulans, Bacillus subtilis, clostridium ou Lactobacillus sporogenes
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
7.
TWO-DIMENSIONAL-MATERIAL-BASED FIELD-EFFECT TRANSISTOR FOR DETECTION OF PATHOGENS AND METHODS FOR MANUFACTURING
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-COV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two-dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
Illustrative embodiments of cellulose nanocrystal modification for adsorbents and sensors are disclosed. In at least one illustrative embodiment, a method of modifying cellulose nanocrystals for use in water-based applications may include obtaining sulfated cellulose nanocrystals (CNCs). The method may also include modifying the CNCs with a silane such as an alkylsilane (e.g., an aminoalkyl silane such as 3-aminopropyl-triethoxysilane (APTES)) to obtain modified CNCs. The modified CNCs enable increased hydrolytic stability (e.g., in a resulting structure, such as a film, coating, gel, or fiber(s), formed from the modified CNCs as compared to a structure formed from the unmodified CNCs). Additionally, the method may include using the modified CNCs in a water-based application.
The invention relates to an HVAC apparatus, method, and system. Aspects of the invention include a supplemental heat source with an air handler unit for a conventional forced air heating and cooling system. The supplemental heat source in one example is a hydronic subsystem. It can be used alone or to supplement the forced air subsystem. Another aspect of the invention includes an air handling subsystem that has a housing that can be highly flexible in configuration and installation. The housing can support internal components, including a hydronic or other supplemental heat source with the forced air components. At least two sides of the housing can be configured for access for maintenance and repair. A control system can be designed to eliminate need for defrost cycle for forced air refrigeration-type subsystem and/or for better maintenance for comfort in the air conditioned space.
An opioid sensor includes a film having two opposed surfaces. The film includes a conductive polymer, and an anchor molecule attached to the conductive polymer so that it is immobilized at a first of the two opposed surfaces. The anchor molecule is to adsorb an opioid. The opioid sensor also includes a working electrode at least partially in contact with a second of the two opposed surfaces; and a counter electrode or counter/reference electrode electrically connected to, and positioned a spaced distance from, the working electrode.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p. ex. par des moyens polarographiques invasifs, p. ex. introduits dans le corps par un cathéter
G01N 27/02 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance
The United States of America, as represented by the Secretary of Agriculture (USA)
Inventeur(s)
Toro Guzman, Haroldo E.
Yu, Qingzhong
Abrégé
Disclosed are recombinant Newcastle disease virus (rNDV) vectors, related polynucleotides, and methods for eliciting an immune response against avian infectious bronchitis virus (IBV) or vaccinating against IBV.
Disclosed herein are systems and methods for reliable and verifiable tracking and reporting of value chain data. In one respect, a management system is provided for a value chain platform, configured to: verify digital certificates confirming suppliers' compliance with emissions tracking criteria of the value chain platform; deploy at least one smart contract on a permissioned blockchain of the value chain platform, the smart contract configured to process one or more emissions tokens of upstream suppliers plus emissions data of a current supplier, to automatically mint a new emissions token representing a combination of the two; and generate a report of cumulative emissions for a given product of the value chain, based on the new emissions token.
A method of target molecule detection includes simultaneously obtaining a first signal from a first working electrode and a second signal from a second working electrode, wherein the first signal is responsive to interaction of the first recognition element with the target molecule in a sample, and the second signal is indicative of background noise from the sample. The method further includes generating a modified signal that is proportional to an instantaneous difference between the first and second signals, wherein the modified signal indicates an amount of the target molecule present in the sample.
A system for improving a physical component may include a processor configured to (1) access a first data storage that may include a plurality of function data objects or a plurality of data vessel data objects that may include references to each other; (2) iterate over the plurality of data vessel data objects, and for each data vessel data object, generate one or more data element instance data objects; (3) select a subset of the plurality of data element instance data objects that include the same data element identifier; (4) order the subset of the data element instance data objects based their respective one or more references to one or more other data element instance data objects; and (5) store the ordered subset of the data element instance data objects in a second data storage as a digital thread.
Technologies for automated test pattern generation include a computing device that identifies one or more stuck-at faults in a logic circuit. The computing device inserts a key gate in the logic circuit at a stuck-at fault to generate a locked logic circuit. The computing device performs a Boolean satisfiability attack to determine an input test pattern associated with the fault and, if no input test pattern exists, identify the fault as redundant. The computing device may identify multiple undetected faults in the logic circuit. The computing device may generate and analyze a separate locked circuit for each undetected fault and/or generate and analyze a locked circuit that models all of the undetected faults. The computing device may test a device under test with all of the generated input test patterns associated with the undetected faults. Other embodiments are described and claimed.
Proposed are an apparatus for and a method of controlling energy for a hybrid electric vehicle. The apparatus includes an input module receiving a traveling condition and a vehicular characteristic of the vehicle, a memory storing an execution program and a parameter that are necessary for carrying out an energy management strategy, and a processor operatively coupled to the input module and the memory, wherein the processor receives the traveling condition and the vehicular characteristic through the input module, according to the energy management strategy, and then determines, based on a first control algorithm, whether or not the vehicle is drivable in an EV mode, wherein, when the vehicle is drivable, the processor enables the vehicle to drive in the EV mode, and wherein, when the vehicle is not drivable, the processor determines and outputs a drive mode and a torque distribution ratio based on a second control algorithm.
B60W 20/11 - Commande de l'apport de puissance de chacun des moteurs primaires pour répondre à la demande de puissance requise utilisant des stratégies de commande prédictive [MPC], c.-à-d. procédés de commande basés sur des modèles de prédiction de performance
B60W 10/06 - Commande conjuguée de sous-ensembles de véhicule, de fonction ou de type différents comprenant la commande des ensembles de propulsion comprenant la commande des moteurs à combustion
B60W 10/08 - Commande conjuguée de sous-ensembles de véhicule, de fonction ou de type différents comprenant la commande des ensembles de propulsion comprenant la commande des unités de traction électrique, p. ex. des moteurs ou des générateurs
B60W 20/13 - Commande de l'apport de puissance de chacun des moteurs primaires pour répondre à la demande de puissance requise afin de rester dans des limites de puissance d'entrée ou sortie de la batterieCommande de l'apport de puissance de chacun des moteurs primaires pour répondre à la demande de puissance requise afin d'éviter la surcharge ou la décharge excessive de la batterie
17.
WIRELESS SENSOR BASED ON LC RESONATOR FOR MONITORING SOIL WATER CONTENT
In at least one illustrative embodiment, a system for wireless soil humidity sensing includes one or more wireless sensors. Each sensor includes a capacitor and an inductor, the capacitor having a dielectric material with a high relative dielectric permittivity that changes in response to changes in environmental humidity. The dielectric material may be a ceramic material such as a core-shell composite including barium titanate (BaTiO3) and silicon dioxide (SiO2). The capacitor may include two opposing sides, with a pair of electrodes positioned on one of the sides. An encapsulation layer such as epoxy may cover the side of the capacitor having the electrode. Sensors may be distributed throughout the soil in an area such as a farm field. The resonant frequency of one or more wireless sensors may be measured, and relative humidity of the soil may be determined based on the resonant frequency. Other embodiments are described and claimed.
G01N 27/22 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la capacité
The present disclosure relates to structures and methods of use of textiles for protection, and more particularly. relates to single layer knitted structures that can be worn as garments to block mosquito bites. The knit structures of the present embodiments can include single layer structures having a unique geometric combination of yarn properties and textiles to block mosquito bites in a single. comfortable layer of fabric. The knit structures can include one or more controllable parameters that can be adjusted to increase and/or decrease the bite blocking ability of the knit structure.
A device including a chamber and a nozzle detachably connected to the chamber, the nozzle defining an aperture, a target carousel disposed within the chamber, a first laser configured to generate a first beam directed toward the target carousel to perform in-situ ablation to form a laser plume, a gas flow system configured to supply gas into the chamber, such that the gas interacts with the laser plume and causes condensation and formation of nanoparticles, and a second laser configured to generate a second beam directed through the interior of the chamber, through the aperture of the nozzle, and toward a substrate disposed outside the device, the second laser beam configured to sinter and crystalize on the substrate the nanoparticles exiting the nozzle.
C23C 14/22 - Revêtement par évaporation sous vide, pulvérisation cathodique ou implantation d'ions du matériau composant le revêtement caractérisé par le procédé de revêtement
B22F 10/25 - Dépôt direct de particules métalliques, p. ex. dépôt direct de métal [DMD] ou mise en forme par laser [LENS]
B22F 10/34 - Commande ou régulation des opérations des caractéristiques de la poudre, p. ex. densité, oxydation ou fluidité
B22F 12/44 - Moyens de rayonnement caractérisés par la configuration des moyens de rayonnement
B22F 12/90 - Moyens de commande ou de régulation des opérations, p. ex. caméras ou capteurs
B23K 26/14 - Travail par rayon laser, p. ex. soudage, découpage ou perçage en utilisant un écoulement de fluide, p. ex. un jet de gaz, associé au faisceau laserBuses à cet effet
B23K 26/144 - Travail par rayon laser, p. ex. soudage, découpage ou perçage en utilisant un écoulement de fluide, p. ex. un jet de gaz, associé au faisceau laserBuses à cet effet l'écoulement de fluide contenant des particules, p. ex. de la poudre
The disclosure provides ink compositions that comprise a 2D material and a solvent and the method to fabricate such compositions. The disclosure also provides the composition and method of fabricating 3D MSCs comprising such ink compositions. Additionally, the disclosure provides a conducting material comprising a battery composition, a 2D material, and a solvent that results in the formation of a composition that may be used for 3D printing of batteries.
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p. ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
B33Y 70/10 - Composites de différents types de matériaux, p. ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
B33Y 80/00 - Produits obtenus par fabrication additive
C09D 11/033 - Encres d’imprimerie caractérisées par des particularités autres que la nature chimique du liant caractérisées par le solvant
H01G 11/24 - Électrodes caractérisées par les propriétés structurelles des matériaux composant les électrodes ou inclus dans les électrodes, p. ex. forme, surface ou porositéÉlectrodes caractérisées par les propriétés structurelles des poudres ou particules utilisées à cet effet
H01G 11/28 - Électrodes caractérisées par leur structure, p. ex. multicouches, selon la porosité ou les caractéristiques de surface agencées ou disposées sur un collecteur de courantCouches ou phases entre les électrodes et les collecteurs de courant, p. ex. adhésifs
H01G 11/38 - Pâtes ou mélanges de carboneLiants ou additifs
H01G 11/86 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants spécialement adaptés pour les électrodes
21.
METHOD TO MAKE HYDROGELS AND CELLULOSE FROM PECTIN- AND PROTEIN-CONTAINING CELLULOSIC BIOMASS
A method of making a hydrogel by treating a cellulosic biomass containing pectin and protein with an aqueous acidic solution at a pH, at a temperature, and for a time sufficient to cause formation of at least a gel fraction containing the hydrogel.
One or more embodiments relate to custom microfabricated magnetic shields that are configured to provide isolation of superconducting electronics (SCE) circuits/chips from each other and an external environment. Whereas most superconducting circuits require magnetic shielding and most shields work by fully encapsulating the circuits, leaving little access for quite rigid and fragile fibers, one or more embodiments allow custom magnetic shield shapes to be fabricated. In embodiments, to improve the shielding, magnetic vias composed of permalloy can be introduced into the shield design. The vias can connect the magnetic shield to a permalloy layer beneath the silicon substrate.
H05K 9/00 - Blindage d'appareils ou de composants contre les champs électriques ou magnétiques
H01L 23/552 - Protection contre les radiations, p. ex. la lumière
H02K 11/01 - Association structurelle de machines dynamo-électriques à des organes électriques ou à des dispositifs de blindage, de surveillance ou de protection pour le blindage contre les champs électromagnétiques
H01L 21/00 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de dispositifs à semi-conducteurs ou de dispositifs à l'état solide, ou bien de leurs parties constitutives
23.
METHOD AND DEVICE FOR NONDESTRUCTIVELY AND IN-SITU MONITORING CORROSION IN OBJECT
The invention in one aspect relates to a method for nondestructively detecting corrosion of an object such as metallic cables. The method includes applying an electronic signal to a device under test (DUT) including said object; measuring signal-transmission characteristics of said object; and determining the corrosion of the object based on the measured signal-transmission characteristics of said object.
The present invention relates to compositions comprising clofazimine and methods for treating cancer. In various embodiments, the compositions and methods further comprise a proteasome inhibitor and/or immunomodulatory drug. The compositions and methods of the present invention may be used for naïve cancers as well as those that have developed resistance to proteasome inhibitors and/or immunomodulatory drugs.
A61K 31/498 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. quinoxaline, phénazine
A61K 31/454 - Pipéridines non condensées, p. ex. pipérocaïne contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p. ex. pimozide, dompéridone
The present disclosure describes genes and proteins of the coenzyme F430 synthetic pathway. The genes and proteins in the pathway find uses as isolated nucleic acids, transformation vectors, a transformation media, genetically modified cells, methods of modulating methanogenesis, methods of modulating methane oxidation, methods of making a tetrapyrrole compound, methods of oxidizing methane, methods of biogenic methane synthesis is provided, methods of assaying an organism for potential methanogenic or methanotrophic activity, and isolated proteins.
Methods of making films with feedstock comprising biomass. The methods include treating a feedstock comprising biomass with an acidic aqueous solution to yield a solid phase and a liquor, generating a forming fluid with the liquor, and generating a film from the forming fluid. Some versions include comminuting the solid phase to generate a comminuted solid phase and including the comminuted solid phase in the forming fluid. The biomass preferably contains relatively high amounts of pectin and protein. The films can be in the form of standalone films or coatings on substrates such as paper. The films provide oil and grease resistance and air impermeability, among other advantages.
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
A23K 40/10 - Mise en forme ou traitement des produits alimentaires pour animaux par agglomérationMise en forme ou traitement des produits alimentaires pour animaux par granulation, p. ex. fabrication de poudres
A23K 10/12 - Produits alimentaires pour animaux obtenus par des procédés microbiologiques ou biochimiques par fermentation de produits naturels, p. ex. d’origine végétale, de matières provenant de déchets d’origine animale ou de biomasse
A23K 20/147 - Dérivés polymériques, p. ex. peptides ou protéines
A61K 49/18 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par un aspect physique particulier, p. ex. émulsions, microcapsules, liposomes
29.
SHRINKING NANOMATERIAL FOR BIOMEDICAL APPLICATIONS
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A thin-film transistor comprises an annealed layer comprising crystalline zinc oxide. A passivation layer is adjacent to the thin-film transistor. The passivation layer has a thickness and material composition such that when a dose of radiation from a radiation source irradiates the thin-film transistor, a portion of the dose that includes an approximate maximum concentration of the dose is located within the annealed layer. The annealed layer has a thickness and threshold displacement energies after it has been annealed such that: a) a difference between a transfer characteristic value of the thin-film transistor before and after the dose is less than a first threshold; and b) a difference between a transistor output characteristic value of the thin-film before and after the dose is less than a second threshold. The thresholds are based on a desired performance of the thin-film transistor.
H01L 21/477 - Traitement thermique pour modifier les propriétés des corps semi-conducteurs, p. ex. recuit, frittage
H01L 21/768 - Fixation d'interconnexions servant à conduire le courant entre des composants distincts à l'intérieur du dispositif
31.
USING LIBERATED AND MODIFIED FIBERS, MICRO-FIBERS, NANO-FIBERS, AND CELLULOSE FROM LIGNOCELLULOSIC PLANT FIBERS, COMBINED WITH ALGAE, AS FEED BINDERS IN COMPOUND FEEDS
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventeur(s)
Aksoy, Burak
Jiang, Zhihua
Aksoy, Mediha
Beck, Benjamin
Abrégé
Animal feed binders made from defibrillated lignocellulosic fibers, animal feeds comprising the defibrillated lignocellulosic fibers, and methods to make animal feeds using the defibrillated lignocellulosic fibers.
A23K 10/37 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons à base de matières résiduelles
A23K 40/10 - Mise en forme ou traitement des produits alimentaires pour animaux par agglomérationMise en forme ou traitement des produits alimentaires pour animaux par granulation, p. ex. fabrication de poudres
C08H 8/00 - Composés macromoléculaires dérivés de matériaux lignocellulosiques
C09J 197/02 - Matériau lignocellulosique, p. ex. bois, paille ou bagasse
32.
MULTI-LAYERED ELECTROCALORIC HEAT PUMP SYSTEMS AND METHODS
In at least one illustrative embodiment, a cooling system includes a heat source, multiple electrocaloric material layers coupled to the heat source, and a heat sink coupled to the electrocaloric material layers. An electric field applied to each electrocaloric material layer is independently controllable. The electric field applied to each electrocaloric material layer is operable to move heat energy from the heat source to the heat sink during an interval, and to restore initial conditions of the electrocaloric material layers during a subsequent interval. The heat sink, the electrocaloric material layers, and the heat source may be bonded together. The electrocaloric material layers and the heat source may be bonded together, and the heat sink may be removably coupled to the electrocaloric material layers. Other embodiments are described and claimed.
The present tree seedling inventory system includes both a mobile platform used to obtain images of seedlings and a tree seedling inventory system to count the seedlings. A recurrent neural network can receive processed imaging data and utilize a model to accurately count the seedlings as the mobile platform passes along a seedling bed. The system may also provide additional accurate seedling quality data about the seedlings, such as shoot height, root collar diameter, and needle coloration.
Provided is an apparatus for supporting an equipment manufacturing process, the apparatus including: a display; and a processor providing a user with a graphical user interface (GUI) for supporting a target-equipment manufacturing process of the user in the form of mixed reality (MR) through the display, and supporting an interaction operation between the GUI and a user action.
G09B 5/02 - Matériel à but éducatif à commande électrique avec présentation visuelle du sujet à étudier, p. ex. en utilisant une bande filmée
G06F 3/04815 - Interaction s’effectuant dans un environnement basé sur des métaphores ou des objets avec un affichage tridimensionnel, p. ex. modification du point de vue de l’utilisateur par rapport à l’environnement ou l’objet
G06F 3/04842 - Sélection des objets affichés ou des éléments de texte affichés
35.
METHOD TO DELIVER CHEMICALS AND NUCLEIC ACIDS TO PLANT CELLS USING CELLULOSE NANOCRYSTALS AS A CARRIER
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (USA)
AUBURN UNIVERSITY (USA)
Inventeur(s)
Khodakovskaya, Mariya
Davis, Virginia
Clouse, Delaney
Vinzant, Kari
Abrégé
A nanomaterial conjugate for delivering an active agent to a plant comprising a nanocarrier and an active agent linked to the nanocarrier. The nanocarrier is cellulose nanocrystal (CNC), and the nanocarrier delivers the active agent across cell walls of cells of the plant.
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
A01N 25/24 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'applicationSubstances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des ingrédients augmentant l'adhérence des ingrédients actifs
A01N 37/38 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou d'un de leurs dérivés, et un atome d'oxygène ou de soufre lié par une liaison simple, liés au même squelette carboné, cet atome d'oxygène ou de soufre ne faisant pas partie d'un groupe carboxylique ou d'un thio-analogue, ou d'une de leurs dérivés, p. ex. acides hydroxycarboxyliques contenant au moins un atome d'oxygène ou de soufre lié à un système cyclique aromatique
36.
HIGH ENTROPY OXIDES AND METHODS OF SYNTHESIS AND USE THEREOF
The present invention provides compositions of compounds comprising a metal M and a macrocyclic ligand represented by General Formula I, and contrast agents comprising the compositions thereof. In various embodiments, the present invention also relates to methods of enhancing methods of enhancing magnetic resonance imaging (MRI) in a living subject, the method comprising administering to a subject an effective amount of a contrast agent comprising a solution or suspension of the composition thereof.
Disclosed are compositions comprising rLS/ArkSe.GMCSF and a live attenuated IBV vaccine, and methods of using the same for inducing an immune response against IBV or vaccinating against IBV.
Described herein DNA-based assays that include nanostructures providing a simple, highly sensitive method for small molecule, biologic and peptide measurements that are optimized for use in a commercial, point-of-care diagnostic settings and systems. These DNA-based assays may include a combination of multiple redox molecules (e.g., methylene blue) such as between 3-8 redox molecules, and a spacer of between about 2 A and 20 A (and in particular between 3 A and 8 A), that results in an assay that has significantly greater signal and greater sensitivity as compared to prior DNA-based assays.
Technologies for platooned include a leader vehicle and one or more follower vehicles each including a computing device. The leader vehicle computing device controls velocity of the leader vehicle within a predetermined route based on a grade profile of the predetermined route. The leader vehicle may perform nonlinear model predictive control using a cost function based on predicted velocity error and predicted fuel consumption. The follower vehicle computing device controls velocity of the follower vehicle within the predetermined route based on headway distance to the leader vehicle and the grade profile. The follower vehicle may perform nonlinear model predictive control using a cost function based on predicted headway error, predicted headway rate of change, and predicted fuel consumption. Other embodiments are described and claimed.
B60W 40/12 - Calcul ou estimation des paramètres de fonctionnement pour les systèmes d'aide à la conduite de véhicules routiers qui ne sont pas liés à la commande d'un sous-ensemble particulier liés à des paramètres du véhicule lui-même
41.
PHAGE-PEPTIDE CONSTRUCTS FOR STIMULATION OF AN ANTI-CANCER IMMUNE RESPONSE AGAINST CD47
Edward Via College of Osteopathic Medicine - Auburn (USA)
Inventeur(s)
Samoylova, Tatiana I.
Samoylov, Alexandre M.
Brock, Kenny V.
Cochran, Anna M.
Gillespie, James W.
Abrégé
Disclosed are recombinant bacteriophage constructs and related exogenous peptide sequences for generating immune responses against CD47. The disclosed recombinant phage constructs bind to antibodies against CD47 and can be administered to an animal to generate an immune response against CD47, including generating anti-CD47 antibodies. The disclosed recombinant phage may comprise an amino acid sequence of CD47, epitopic fragments, variants, or functional mimics thereof. Also disclosed are methods for making and selecting such recombinant phage constructs and compositions that comprise such constructs (e.g., compositions for inducing an immune response against CD47 including pharmaceutical or veterinary compositions used as vaccines). Also disclosed are recombinant polynucleotides comprising genomic nucleic acid of the recombinant phage constructs disclosed herein.
A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides
Microorganisms and microbial production methods for the biosynthesis of ester compounds are provided. Useful examples employ microorganisms that have been genetically modified to express alcohol acyltransferases, either from other species or that have been modified to increase their activity in catalyzing the esterification of alcohols. Additional useful examples employ microorganisms that have been genetically modified to express lipases, either from other species or that have been modified to increase their activity in catalyzing the esterification of organic acids. Additional modifications are presented that significantly increase ester production.
Engineered wood products and binder compositions for cold-pressed applications are provided. Methods are also provided for formulating binders and producing the engineered wood products. The binder comprises a soy product and an adhesive formulation. The binders are prepared by mixing the soy product with the adhesive formulation prior to application to a lignocellulosic material to form the engineered wood. The present compositions and methods provide enhanced bonding and shorter holding time at decreased cost.
Engineered wood products and binder compositions for cold-pressed applications are provided. Methods are also provided for formulating binders and producing the engineered wood products. The binder comprises a soy product and an adhesive formulation. The binders are prepared by mixing the soy product with the adhesive formulation prior to application to a lignocellulosic rnaterial to forrn the engineered wood. The present cornpositions and rnethods provide enhanced bonding and shorter holding tirne at decreased cost.
B32B 7/12 - Liaison entre couches utilisant des adhésifs interposés ou des matériaux interposés ayant des propriétés adhésives
B32B 21/04 - Produits stratifiés composés essentiellement de bois, p. ex. une planche de bois, une feuille de placage, une feuille de bois aggloméré comprenant du bois comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique
B32B 37/12 - Procédés ou dispositifs pour la stratification, p. ex. par polymérisation ou par liaison à l'aide d'ultrasons caractérisés par l'usage d'adhésifs
C09J 201/00 - Adhésifs à base de composés macromoléculaires non spécifiés
45.
ASSAY METHOD FOR POINT OF CARE QUANTIFICATION OF AN IMMUNOPHILIN-BINDING IMMUNOSUPPRESSANT DRUG
Methods and apparatuses, including assays, for detection and/or quantification of tacrolimus that utilize nucleic acid-based nanostructures linked to tacrolimus. In particular, described herein are biosensors having a sensing mechanism configured to react to a tacrolimus-specific binding agent, such as an aptamer or antibody that binds tacrolimus. In some variations, these methods and apparatuses may be configured to provide an electrochemical read-out in which the nucleic acid-based nanostructure is operated in conjunction with a tacrolimus-specific binding agent for sample quantification. A biosensor or a set of biosensors as described herein can be used as a standalone measurement system for tacrolimus and/or as part of a multiplexed cartridge for multiple analytes.
G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques
C12Q 1/6804 - Analyse d’acides nucléiques utilisant des immunogènes
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
46.
N-HALAMINE CONTAINING FIBROUS COMPOSITIONS AND USES THEREOF
The present disclosure provides fibrous composition comprising a soluble or a dispersible N-halamine, for example 1-chloro-2,2,5,5-tetramethyl-4-imidazolidinone (i.e., compound I). Additionally, the disclosure provides methods for producing the fibrous compositions comprising a soluble or a dispersible N-halamine as well as methods for protecting a person from an infection using the fibrous compositions comprising a soluble or a dispersible N-halamine. The compositions and methods according to the present disclosure provide several advantages, such as stability, less time to provide sufficient antimicrobial inactivation, and are inexpensive and require lower amount of active concentrations to be effective.
A61L 15/24 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carboneLeurs dérivés
A61L 15/46 - Désodorisants ou produits pour neutraliser les mauvaises odeurs, p. ex. pour inhiber la formation d'ammoniac ou la multiplication de bactéries
The present tree seedling inventory system includes both a mobile platform used to obtain images of seedlings and a tree seedling inventory system to count the seedlings. A recurrent neural network can receive processed imaging data and utilize a model to accurately count the seedlings as the mobile platform passes along a seedling bed. The system may also provide additional accurate seedling quality data about the seedlings, such as shoot height, root collar diameter, and needle coloration.
G06V 10/147 - Détails de capteurs, p. ex. lentilles de capteurs
G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
A novel bacteria strain Bacillus velezensis ABN1001 was deposited at the International Depositary Authority of Canada. The bacteria, or mutants thereof, or metabolites produced by the bacteria, can be used in compositions for controlling plant disease, treating plant disease, and/or promoting plant growth.
Described herein are DNA-nanostructures that can be used in an assay to detect and/or quantify an analyte of interest. Aspects of the DNA-nanostructure can include a single DNA molecule composed of hairpin structural motifs, an anchor recognition moiety, and a signal moiety, where the anchor recognition moiety and the signal moiety are in effective proximity to each other such that the tethered diffusion of the signal molecule can be altered based upon binding status of the anchor recognition moiety. Also described herein are methods of making and using the DNA-nanostructures.
Provided is a method of treating a disease caused by a nidovirus that encodes Nsp15, such as a coronavirus, an arterivirus, or a torovirus, in a subject in need thereof comprising administering a therapeutically effective amount of an active agent selected from 3′-uridylic acid, 5′-uridylic acid, citrate, methacycline, meclocycline sulfosalicylate, mitoxantrone, epirubicin hydrochloride, daunorubicin hydrochloride, sorafenib, sunitinib malate, primaquine diphosphate, closantel, isopropyl ester of N4-hydroxycytidine, GpU dinucleotide or derivatives thereof, and tipiracil or N-substituted derivatives thereof. Further provided are a method of inhibiting an Nsp15 endoribonuclease of a nidovirus that encodes Nsp15 and compounds of formulas (I′) and (II′).
A61K 31/7072 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées ayant des groupes oxo liés directement au cycle pyrimidine, p. ex. cytidine, acide cytidylique ayant deux groupes oxo liés directement au cycle pyrimidine, p. ex. uridine, acide uridylique, thymidine, zidovudine
A61K 31/7084 - Composés ayant deux nucléosides ou nucléotides, p. ex. dinucléotide de la nicotinamide-adénine, dinucléotide de la flavine-adénine
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61P 31/14 - Antiviraux pour le traitement des virus ARN
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
caps being headwear; shirts; t-shirts Arranging and conducting athletic competitions, athletic events, athletic tournaments, and athletic exhibitions for entertainment purposes
The present disclosure describes system and methods for determining cardiac events from a physiological data signal and optionally constructing a Pressure-Volume (PV) loop display from non-simultaneously acquired measurements of pressure and volume data. One such method comprises obtaining, by a computing device, a physiological data signal of a heart of an individual; identifying, by the computing device, features of the physiological data signal and applying the features as inputs to a prediction model; determining, by the computing device using the prediction model, the cardiac events for one or more valves of the heart, wherein the cardiac events include timing of opening and closing of the one or more valves of the heart; and outputting, by the computing device, the cardiac events determined using the prediction model. The physiological data signal can be combined with non-simultaneously acquired volume data to create a PV loop display.
In at least one illustrative embodiment, an electromagnetic filter may include a transfer pipe and multiple electromagnetic filter elements positioned in an interior volume of the pipe. Each electromagnetic filter element includes a support comb, a solenoid coupled to the support comb, and multiple magnetic members arranged in a planar array positioned within an opening of the support comb. Each magnetic member may rotate about an end that is coupled to the support comb. The magnetic members may be magnetostrictive sensors and may include a biorecognition element to bind with a target microorganism. A method for fluid filtration includes coupling the electromagnetic filter between a fluid source and a fluid destination, energizing the solenoids of each electromagnetic filter elements, and flowing a fluid media through the transfer pipe of the electromagnetic filter. The fluid media may be liquid food such as fruit juice. Other embodiments are described and claimed.
B03C 1/033 - Éléments constitutifsOpérations auxiliaires caractérisés par le circuit magnétique
A23L 3/00 - Conservation des aliments ou produits alimentaires, en général, p.ex. pasteurisation ou stérilisation, spécialement adaptée aux aliments ou produits alimentaires
A23L 3/26 - Conservation des aliments ou produits alimentaires, en général, p.ex. pasteurisation ou stérilisation, spécialement adaptée aux aliments ou produits alimentaires par irradiation sans chauffage
B01D 35/06 - Filtres utilisant l'électricité ou le magnétisme
B03C 1/032 - Systèmes de nettoyage des matrices de filtration
B03C 1/034 - Éléments constitutifsOpérations auxiliaires caractérisés par le circuit magnétique caractérisés par les éléments de matrice
G01N 29/22 - Recherche ou analyse des matériaux par l'emploi d'ondes ultrasonores, sonores ou infrasonoresVisualisation de l'intérieur d'objets par transmission d'ondes ultrasonores ou sonores à travers l'objet Détails
G01N 33/543 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
C02F 103/32 - Nature de l'eau, des eaux résiduaires ou des eaux ou boues d'égout à traiter provenant de l'industrie alimentaire, p. ex. eaux résiduaires de brasseries
G01N 15/01 - Recherche de caractéristiques de particulesRecherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux spécialement adaptée aux cellules biologiques, p. ex. aux cellules sanguines
41 - Éducation, divertissements, activités sportives et culturelles
43 - Services de restauration (alimentation); hébergement temporaire
Produits et services
Private social club services, namely, arranging, organizing, and hosting social events, get-togethers, and parties for club members Bar services; restaurant services
The present disclosure provides a method of producing a lubricant composition comprising the steps of hydrolyzing a starting material to provide a hydrolyzed product mixture, reacting the hydrolyzed product mixture under conditions capable of producing a condensation product mixture, contacting the condensation product mixture with a cyclic compound to provide a coupled product mixture, and hydrogenating the coupled product mixture to provide the lubricant composition. In addition, other methods and compositions thereof are also provided.
A method for manufacturing individualized protective gear such as pads based on a scan, and the resulting pads, are disclosed herein. A garment comprising a pocket with a visibly defined border is selected. A wearer dons the garment. A scan is taken of at least a portion of the garment over the wearer's body at the location where the pocket is disposed over the wearer's body. The scan is converted to a mesh model. The mesh model is used to define a first surface of the equipment configured to form to the wearer's body at the location where the pocket is disposed over the wearer's body and a second surface offset from the first surface. The model may be checked to identify production defects, which, if present, are removed. The equipment may be manufactured using additive printing technology.
A41H 43/00 - Autres méthodes, machines ou appareils
A41D 13/015 - Vêtements protecteurs de travail ou de sport, p. ex. blouses de chirurgien ou vêtements protégeant des coups ou des chocs avec des moyens absorbeurs de chocs
A41D 13/05 - Vêtements protecteurs de travail ou de sport, p. ex. blouses de chirurgien ou vêtements protégeant des coups ou des chocs protégeant uniquement une partie particulière du corps
A41H 1/02 - Dispositifs pour la prise des mesures sur le corps
A41H 1/06 - Dispositifs pour le tracé des mesures en combinaison avec le marquage
A41H 3/00 - Patrons de coupeMéthodes pour dessiner ou tracer de tels patrons, p. ex. sur le tissu
A41H 3/04 - Fabrication des patrons par moulage sur le corps
Methods of dewatering viscous materials are provided. The method comprises contacting the viscous material with pressurized carbon dioxide at a temperature and for a time wherein at least a fraction of water is expressed from the viscous material. Then the pressure is released, and the water expressed from the viscous material is removed to yield a dewatered product. Exemplary viscous materials that can be dewatered by the method include black liquor from wood pulping operations, wet lignin, wet super water absorbent polymers and sugar solutions. The pressurized carbon dioxide is present in subcritical or supercritical form. The method provides dewatering at reduced cost.
MEMS-based sensors can experience undesirable signal frequencies caused by vibrations, shocks, and accelerations, among other phenomena. A microisolation system can isolate individual MEMS-based sensors from undesirable signal frequencies and shocks. An embodiment of a system for microisolation of a MEMS-based sensor can include an isolation platform connected to one or more folded springs. Another embodiment of a system for microisolation can include an isolation platform and/or a frame connected to a mesh damping mechanism. In at least one embodiment, a mesh damping mechanism can be a microfibrous metal mesh damper. In one or more embodiments, a system for microisolation can include an isolation platform connected to one or more L-shaped springs, and a thickness of the one or more L-shaped springs can be less than a thickness of the isolation platform.
B81B 7/02 - Systèmes à microstructure comportant des dispositifs électriques ou optiques distincts dont la fonction a une importance particulière, p. ex. systèmes micro-électromécaniques [SMEM, MEMS]
59.
DIROFILARIA VOLATILE ORGANIC COMPOUND SIGNATURES AND USES THEREOF
Described herein are Dirofilarial exhalant signatures and methods of detecting a Dirofilaria signature in a non-blood biological sample, such as exhalant, that can be used to detect Dirofilarial infection in a subject, such as a canine.
G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
A61K 31/555 - Composés hétérocycliques contenant des métaux lourds, p. ex. hémine, hématine, mélarsoprol
A pharmaceutical composition comprises a metal nanoparticle having an average diameter of about 0.5 nm to about 5 nm. The composition may be used to treat cancer or an anosmia-related disease.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
A61K 9/14 - Préparations médicinales caractérisées par un aspect particulier à l'état particulaire, p. ex. poudres
The present disclosure provides a method of producing a lubricant composition comprising the steps of hydrolyzing a starting material to provide a hydrolyzed product mixture, reacting the hydrolyzed product mixture under conditions capable of producing a condensation product mixture, contacting the condensation product mixture with a cyclic compound to provide a coupled product mixture, and hydrogenating the coupled product mixture to provide the lubricant composition. In addition, other methods and compositions thereof are also provided.
C10M 169/04 - Mélanges de matériaux de base et d'additifs
C10M 175/00 - Traitement des lubrifiants usés pour récupérer les produits utiles
C10M 177/00 - Méthodes particulières de préparation des compositions lubrifiantesModification chimique par post-traitement des constituants ou de la composition lubrifiante elle-même, non couverte par d'autres classes
Described herein are nucleic acid-based electrochemical proximity assays (ECPAs) for sample quantification. The invention may also include a biosensor with a sensing mechanism that uses a pair of aptamers or antibodies that bind the target of interest. More specifically, the invention relates to an electrochemical-based read out of a sensing mechanism that uses a nucleic acid-based proximity assay in conjunction with a pair of aptamers or antibodies for sample quantification. The biosensor or a set of biosensors can be used either as a standalone measurement system for a single analyte target or as a component of a multiplexed cartridge for multiple analytes.
The present disclosure relates to structures and methods of use of textiles for protection, and more particularly, relates to single layer knitted structures that can be worn as garments to block mosquito bites. The knit structures of the present embodiments can include single layer structures having a unique geometric combination of yarn properties and textiles to block mosquito bites in a single, comfortable layer of fabric. The knit structures can include one or more controllable parameters that can be adjusted to increase and/or decrease the bite blocking ability of the knit structure.
A01M 29/34 - Épouvantails ou dispositifs répulsifs, p. ex. pour oiseaux empêchant l'accès ou obstruant le passage, p. ex. au moyen de barrières, de pics, de cordons, d'obstacles ou d'aspersion d'eau spécialement adaptés aux insectes
A01M 29/30 - Épouvantails ou dispositifs répulsifs, p. ex. pour oiseaux empêchant l'accès ou obstruant le passage, p. ex. au moyen de barrières, de pics, de cordons, d'obstacles ou d'aspersion d'eau
D04B 1/00 - Procédés de tricotage trame pour la production de tricots ou d'articles ne dépendant pas de l'emploi de machines spécialesTricots ou articles définis par de tels procédés
D04B 1/24 - Procédés de tricotage trame pour la production de tricots ou d'articles ne dépendant pas de l'emploi de machines spécialesTricots ou articles définis par de tels procédés spécialement conçus pour le tricotage d'articles de configuration particulière articles vestimentaires
D04B 1/14 - Autres tricots ou articles caractérisés principalement par l'emploi de matières spéciales pour le fil
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Educational services, namely, providing academic support through arranging and conducting academic and professional workshops in the field of engineering, arranging and conducting educational study groups in the field of engineering, and individual career counseling, namely, providing advice concerning education options to pursue career opportunities in the field of engineering, all of the above for demographic groups that are underrepresented in the field of engineering
65.
VISION INSPECTION SYSTEM BASED ON DEEP LEARNING AND VISION INSPECTING METHOD THEREOF
The present disclosure relates to a vision inspection system based on deep learning and a vision inspection method of. The vision inspection system based on deep learning according to the present disclosure includes a GT generation module that generates a GT for a region of interest of a car part image, a learning module that receives learning data from the GT generation module, performs learning based on deep learning, and outputs a weight file, and an interface module that detects a defect with respect to an image file received from a vision program by using the weight file, and returns a defect detection result to the vision program.
A method for manufacturing individualized protective gear such as pads based on a scan, and the resulting pads, are disclosed herein. A garment comprising a pocket with a visibly defined border is selected. A wearer dons the garment. A scan is taken of at least a portion of the garment over the wearer's body at the location where the pocket is disposed over the wearer's body. The scan is converted to a mesh model. The mesh model is used to define a first surface of the equipment configured to form to the wearer's body at the location where the pocket is disposed over the wearer's body and a second surface offset from the first surface. The model may be checked to identify production defects, which, if present, are removed. The equipment may be manufactured using additive printing technology.
The present invention relates to the production of cell cultures and tissues from undifferentiated pluripotent stem cells using three-dimensional biomimetic materials. The resultant cell cultures or tissues can be used in any of a number of protocols including testing chemicals, compounds, and drugs. Further, the methods and compositions of the present invention further provide viable cell sources and novel cell delivery platforms that allow for replacement of diseased tissue and engraftment of new cardiomyocytes from a readily available in vitro source. The present invention includes novel methods required for the successful production of cell cultures and tissues, systems and components used for the same, and methods of using the resultant cell and tissue compositions.
EDWARD VIA VIRGINIA COLLEGE OF OSTEOPATHIC MEDICINE (USA)
Inventeur(s)
Castellano, Vitale Kyle
Zabala, Michael
Burch, Thomas E.
Burch, Hayden
Commander, Jonathan
Brock, Kenny V.
Abrégé
Disclosed herein is a device for repeatably and accurately measuring the threshold sensitivity of the skin on a body part or surface such as the plantar surface of the foot. The machine uses a monofilament pressure test, where a monofilament is applied to the surface of the skin until it buckles at a corresponding force. The device may measure a broad range of pressures and responsive sensation in the patient using multiple applications of the monofilament. The patient indicates a positive or negative response, based on whether the patient sensed the monofilament pressure. The machine may include a foot clamping assembly, a support chassis, a linear motion translation assembly for locating the monofilament at a given position for testing, and a camera for taking images used to identify testing locations and report results. Methods of use and testing protocols are also described herein.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventeur(s)
Toro Guzman, Haroldo, E.
Yu, Qingzhong
Abrégé
Disclosed are recombinant Newcastle disease virus (rNDV) vectors, related polynucleotides, and methods for eliciting an immune response against avian infectious bronchitis virus (IBV) or vaccinating against IBV. In particular, the recombinant proteins, compositions, vectors, kits, and methods may be utilized to immunize poultry against disease associated with IBV infection or to protect poultry from IBV infection.
Descried in certain example embodiments herein are engineered fish, particularly engineered catfish, that are engineered to contain modified myostatin, melanocortin-4 receptor, and/or one or more n-3 fatty acid biosynthesis pathway genes and/or gene products.
Therapeutic or prophylactic compositions providing an active agent, such as an antigen or a vector that contains and expresses an antigen, encapsulated in or incorporated into a biodegradable polymeric particle are provided. The compositions can also provide an active agent that is not encapsulated in or incorporated into the biodegradable polymeric particle in order to provide an initial or prime delivery of the active agent. Particles or composites providing an active agent encapsulated by a first and second polymer are also provided, wherein polymers are distributed in a gradient from a core of the composite to a surface of the composite, and configured to provide a delayed release of the active agent by a period of 7 days to 6 months. Methods of producing composites are also provided. Pharmaceutical formulations providing a single dose composition are also provided, along with methods for administering the pharmaceutical compositions to a subject in need thereof a therapeutically effective amount of an active agent are provided.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventeur(s)
Chin, Bryan A.
Torbert, Iii, Henry Allen
Yakubova, Galina N.
Kavetskiy, Aleksandr
Sargsyan, Nikolay
Abrégé
A system for analyzing soil content of a field includes a data acquisition unit configured to detect gamma spectra of each of a plurality of soil samples, wherein a surface area of the field is divided into a plurality of portions and the plurality of soil samples comprises at least one soil sample from each of the plurality of portions, a navigation unit configured to detect geographic coordinates of each of the plurality of soil samples, a data analysis unit configured to associate the detected gamma spectra of each of the plurality of soil samples with the geographic coordinates of the soil sample and determine a weight percent of at least one element within each of the soil samples based on the detected gamma spectra, and an element content map unit configured to generate a map indicating concentration of the at least one element within the soil of the field.
G01N 23/221 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux utilisant l'analyse par activation
G01N 23/22 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux
G01N 23/222 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux utilisant l'analyse par activation en utilisant l'analyse par activation neutronique [NAA]
G01N 23/223 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en irradiant l'échantillon avec des rayons X ou des rayons gamma et en mesurant la fluorescence X
G01V 5/02 - Prospection ou détection au moyen de rayonnement ionisant, p. ex. de la radioactivité naturelle ou provoquée spécialement adaptée à la reconnaissance en surface, p. ex. à partir d'un avion
G01V 5/22 - Interrogation active, c.-à-d. par irradiation des objets ou des biens à l’aide de sources de rayonnement externes, p. ex. en utilisant des rayons gamma ou des rayons cosmiques
73.
A BACILLUS STRAIN AND METHODS OF ITS USE FOR PLANT GROWTH PROMOTION
The present invention relates to a composition comprising a biologically pure culture of Bacillus spp. strain NRRL B-67746 and mutants of that strain having all the identifying characteristics of the strain. The present invention also provides a method of promoting plant growth, wherein the method comprises applying such strain or mutants to the plant, to a part of the plant and/or to a locus of the plant.
The invention relates to an HVAC apparatus, method, and system. Aspects of the invention include a supplemental heat source with an air handler unit for a conventional forced air heating and cooling system. The supplemental heat source in one example is a hydronic subsystem. It can be used alone or to supplement the forced air subsystem. Another aspect of the invention includes an air handling subsystem that has a housing that can be highly flexible in configuration and installation. The housing can support internal components, including a hydronic or other supplemental heat source with the forced air components. At least two sides of the housing can be configured for access for maintenance and repair. A control system can be designed to eliminate need for defrost cycle for forced air refrigeration-type subsystem and/or for better maintenance for comfort in the air conditioned space.
F24F 5/00 - Systèmes ou appareils de conditionnement d'air non couverts par ou
F24D 12/02 - Autres systèmes de chauffage central avec plus d'une source de chaleur
F24D 19/10 - Aménagements ou montage des dispositifs de commande ou de sécurité
75.
APPARATUS AND PROCESS FOR TREATING BIOMASS FOR ON-SITE PRODUCTION OF CELLULOLYTIC ENZYMES AND METHOD OF USING THE ENZYMES TO MANUFACTURE FUELS AND CHEMICALS
An integrated process and corresponding apparatus that produces a relatively clean, delignified cellulose product from lignocellulosic biomass. The method includes treating a portion of the delignified cellulose itself as a substrate to produce on-site cellulolytic enzymes, including further treating the remaining delignified cellulose with the resulting cellulolytic enzymes for in situ enzymatic hydrolysis. The process and apparatus are useful to produce fermentable sugars for cost-effective manufacturing of fermentable sugars, fuels, bioproducts and chemicals.
C07K 1/02 - Procédés généraux de préparation de peptides en solution
C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
C08H 7/00 - LignineLignine modifiéeProduits dérivés à haut poids moléculaire
C08H 8/00 - Composés macromoléculaires dérivés de matériaux lignocellulosiques
C12N 9/42 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons bêta-glucosidiques-1, 4, p. ex. cellulase
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
Apparatus and process for treating biomass for on-site production of cellulolytic enzymes and method of using the enzymes to manufacture fuels and chemicals
An integrated process and corresponding apparatus that produces a relatively clean, delignified cellulose product from lignocellulosic biomass. The method includes treating a portion of the delignified cellulose itself as a substrate to produce on-site cellulolytic enzymes, including further treating the remaining delignified cellulose with the resulting cellulolytic enzymes for in situ enzymatic hydrolysis. The process and apparatus are useful to produce fermentable sugars for cost-effective manufacturing of fermentable sugars, fuels, bioproducts and chemicals.
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
C13K 1/02 - GlucoseSirops glucosés obtenus par saccharification de matières cellulosiques
C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
C08B 37/00 - Préparation des polysaccharides non prévus dans les groupes Leurs dérivés
C13K 13/00 - Sucres non prévus ailleurs dans la présente classe
C08H 8/00 - Composés macromoléculaires dérivés de matériaux lignocellulosiques
77.
APPARATUS AND PROCESS FOR TREATING BIOMASS FOR ON-SITE PRODUCTION OF CELLULOLYTIC ENZYMES AND METHOD OF USING THE ENZYMES TO MANUFACTURE FUELS AND CHEMICALS
in situin situ enzymatic hydrolysis. The process and apparatus are useful to produce fermentable sugars for cost-effective manufacturing of fermentable sugars, fuels, bioproducts and chemicals.
Disclosed herein is a device for repeatably and accurately measuring the threshold sensitivity of the skin on a body part or surface such as the plantar surface of the foot. The machine uses a monofilament pressure test, where a monofilament is applied to the surface of the skin until it buckles at a corresponding force. The device may measure a broad range of pressures and responsive sensation in the patient using multiple applications of the monofilament. The patient indicates a positive or negative response, based on whether the patient sensed the monofilament pressure. The machine may include a foot clamping assembly, a support chassis, a linear motion translation assembly for locating the monofilament at a given position for testing, and a camera for taking images used to identify testing locations and report results. Methods of use and testing protocols are also described herein.
A medical backpack for storing medical supplies and medical equipment is disclosed. The medical backpack can be used by medics working in rural or remote areas that are not accessible by car and where access to hospitals and medical supplies is limited or non-existent. The medical backpack is light enough to carry long distances and comprised of a number of different compartments that are flexible to equip with various supplies for specific needs and circumstances.
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Live animals, namely, dogs Providing security screening services in the nature of dog detection services, namely, providing dogs that detect explosives and contraband for the protection of property and individuals
A medical backpack for storing medical supplies and medical equipment is disclosed. The medical backpack can be used by medics working in rural or remote areas that are not accessible by car and where access to hospitals and medical supplies is limited or non-existent. The medical backpack is light enough to carry long distances and comprised of a number of different compartments that are flexible to equip with various supplies for specific needs and circumstances.
A45F 3/04 - Sacs ou paquetages portés sur le corps au moyen de deux courroies passant sur les épaules
A61B 50/30 - Récipients spécialement adaptés à l'emballage, la protection, la distribution, la collecte ou l'élimination des appareils ou des instruments chirurgicaux ou de diagnostic
A45F 3/00 - Articles de voyage ou de campingSacs ou paquetages portés sur le corps
Culture systems and methods of using same. The systems include a housing defining an inner space. The inner space includes a headspace and at least a portion of a reservoir. A surface for immobilizing cells is moveable between the headspace and the reservoir. The systems can be used for coculturing methanotrophs and phototrophs for processing biogas and wastewater, particularly from anaerobic digesters.
C02F 3/32 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les animaux ou végétaux utilisés, p. ex. les algues
C02F 3/34 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout caractérisé par les micro-organismes utilisés
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 1/02 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'agitationAppareillage pour l'enzymologie ou la microbiologie avec des moyens d'échange de chaleur
C12M 1/107 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens pour recueillir les gaz de fermentation, p. ex. le méthane
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
An air conditioning device includes an inlet plenum to receive input air, a sprayer to charge at least one of a plurality of liquid droplets generating at least one charged liquid droplet and to release the charged liquid droplet into air rotating vortex, moving the input air within a spray chamber, to cause the charged liquid droplet to attract and attach a vapor molecule of the input air separating the molecule from the input air, a separation chamber to cause the liquid droplet with the attached vapor molecule to separate from the vortex to condense and collect as liquid, and an air outlet to direct, away from the air conditioning device, output air including air remaining following the separation, from the vortex, of the liquid droplet with the attached vapor molecule, where a first humidity of the output air is less than a second humidity of the input air.
B01D 53/30 - Commande par appareil d'analyse des gaz
B01D 45/16 - Séparation de particules dispersées dans des gaz ou des vapeurs par gravité, inertie ou force centrifuge en utilisant la force centrifuge produite par le mouvement hélicoïdal du courant gazeux
B01D 53/32 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par effets électriques autres que ceux prévus au groupe
B04C 5/103 - Bâtis ou éléments des appareils, p. ex. volets ou guides
B04C 9/00 - Combinaisons avec d'autres dispositifs, p. ex. avec des ventilateurs
F24F 3/14 - Systèmes de conditionnement d'air dans lesquels l'air conditionné primaire est fourni par une ou plusieurs stations centrales aux blocs de distribution situés dans les pièces ou enceintes, blocs dans lesquels il peut subir un traitement secondaireAppareillage spécialement conçu pour de tels systèmes caractérisés par le traitement de l'air autrement que par chauffage et refroidissement par humidificationSystèmes de conditionnement d'air dans lesquels l'air conditionné primaire est fourni par une ou plusieurs stations centrales aux blocs de distribution situés dans les pièces ou enceintes, blocs dans lesquels il peut subir un traitement secondaireAppareillage spécialement conçu pour de tels systèmes caractérisés par le traitement de l'air autrement que par chauffage et refroidissement par déshumidification
84.
TECHNOLOGIES FOR MICROELECTROMECHANICAL SYSTEMS WITH COMPOSABLE PIEZOELECTRIC ACTUATORS
In at least one illustrative embodiment, a microelectromechanical system (MEMS) includes a composable piezoelectric actuator electrically coupled to a terminal. In response to a voltage applied across electrodes of the actuator, a piezoelectric rod moves from an initial position to a displaced position. In an embodiment, the MEMS includes two terminals, a resistive element is coupled between the terminals, and when in the displaced position the rod contacts one of the terminals. In an embodiment, the MEMS includes three terminals, and when a threshold voltage is applied to one of the terminals, the rod moves to the displaced position and allows current to flow between the other two terminals. In an embodiment, the MEMS includes a primary set of actuators that are mechanically but not electrically connected to a secondary set of actuators. An output terminal is coupled to the second set of actuators. Other embodiments are described and claimed.
In at least one illustrative embodiment, a microelectromechanical system (MEMS) includes a composable piezoelectric actuator electrically coupled to a terminal. In response to a voltage applied across electrodes of the actuator, a piezoelectric rod moves from an initial position to a displaced position. In an embodiment, the MEMS includes two terminals, a resistive element is coupled between the terminals, and when in the displaced position the rod contacts one of the terminals. In an embodiment, the MEMS includes three terminals, and when a threshold voltage is applied to one of the terminals, the rod moves to the displaced position and allows current to flow between the other two terminals. In an embodiment, the MEMS includes a primary set of actuators that are mechanically but not electrically connected to a secondary set of actuators. An output terminal is coupled to the second set of actuators. Other embodiments are described and claimed.
Described herein are Dirofilarial exhalant signatures and methods of detecting a Dirofilaria signature in a non-blood biological sample, such as exhalant, that can be used to detect Dirofilarial infection in a subject, such as a canine.
A61K 31/555 - Composés hétérocycliques contenant des métaux lourds, p. ex. hémine, hématine, mélarsoprol
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
The present disclosure provides a means to remove oxidative compounds such as free halogen and chloramines from a liquid, while also providing components with antimicrobial properties in order to combat biofouling and the shedding of pathogens into liquids. In particular, methods of removing an oxidative compound from a liquid in which the liquid is contacted with one or more polymeric beads. As described herein, the oxidative compound binds to the polymeric bead and is removed from the liquid.
B01J 20/28 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation caractérisées par leur forme ou leurs propriétés physiques
The present disclosure provides a means to remove oxidative compounds such as free halogen and chloramines from a liquid, while also providing components with antimicrobial properties in order to combat biofouling and the shedding of pathogens into liquids. In particular, methods of removing an oxidative compound from a liquid in which the liquid is contacted with one or more polymeric beads. As described herein, the oxidative compound binds to the polymeric bead and is removed from the liquid.
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12Q 1/00 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions
G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
90.
TWO-DIMENSIONAL-MATERIAL-BASED FIELD-EFFECT TRANSISTOR FOR DETECTION OF PATHOGENS AND METHODS FOR MANUFACTURING
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide (104) that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two- dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
G01N 27/414 - Transistors à effet de champ sensibles aux ions ou chimiques, c.-à-d. ISFETS ou CHEMFETS
B82Y 15/00 - Nanotechnologie pour l’interaction, la détection ou l'actionnement, p. ex. points quantiques comme marqueurs en dosages protéiques ou moteurs moléculaires
91.
METAL ADDITIVE MANUFACTURING APPARATUS AND METHODS
A metal 3D printer is disclosed for fabricating metal articles by depositing molten metal onto a print bed. The metal 3D printer has a print head having a crucible and nozzle. The crucible melts metal and the nozzle deposits the molten metal onto the print bed. The 3D printer further includes an induction heating system to heat the print head and a heated print bed disposed below the nozzle. The metal 3D printer also has a computer numerically controlled (CNC) gantry for moving the print head and the print bed relative to each other along X, Y, and Z axes. Shielding gas may be directed proximate to the crucible or the nozzle. The feedstock for the printer may be a plurality of wire strands braided together. A mesh overlay may be positioned on top of the print bed.
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p. ex. modélisation par dépôt de fil en fusion [FDM]
A metal 3D printer is disclosed for fabricating metal articles by depositing molten metal onto a print bed. The metal 3D printer has a print head formed of a crucible and a nozzle. The crucible heats the molten metal and the nozzle deposits the molten metal onto the print bed. The 3D printer further includes an induction heating system to heat the print head and a heated print bed disposed below the nozzle. The metal 3D printer also comprises a computer numerically controlled (CNC) gantry configured to move the print head and the print bed relative to each other along X, Y, and Z axes. A shielding gas blower may direct a first stream of shielding gas proximate to the crucible and a second stream of shielding gas proximate to the nozzle. The feedstock for the printer may comprise a plurality of wire strands braided together. A mesh overlay may be positioned on top of the print bed.
In at least one illustrative embodiment, a field-effect transistor biosensor for detection of a pathogen includes a substrate and a channel formed from a two-dimensional monolayer or few-layer metal chalcogenide that is functionalized with a biorecognition element. The biorecognition element may be an antibody, such as an antibody for the SARS-CoV-2 spike protein. A method for manufacturing the biosensor includes depositing an amorphous two-dimensional material on the substrate with pulsed laser ablation, crystallizing the amorphous two-dimensional material to generate a two-dimensional monolayer coupled to the substrate, and activating a surface of the two-dimensional material with the biorecognition element after crystallizing the amorphous two-dimensional material. The composition of the two-dimensional material may be tuned. The substrate may be photolithographically patterned. Other embodiments are described and claimed.
The devices, methods, and compositions disclosed herein accomplish robust cell encapsulation in polymer microparticles using a vertically oriented microfluidic device. A hydrophilic polymer precursor solution is flowed into a first inlet channel, which extends inward from an upper surface of the device housing. A hydrophobic fluid is flowed into a second inlet channel, which extends inward from a lower surface of the device housing. The two inlet channels meet at a junction, and an outlet channel extends away from the two inlet channels. When the two inwardly flowing streams meet at the junction, the polymer precursor solution disperses into the hydrophobic fluid. The dispersed precursor droplets are photopolymerized into microparticles as they travel through the outlet channel. The resulting microparticles are highly uniform, and are larger than conventionally formed microparticles. Cells of varying types can be encapsulated with high viability and spatial uniformity.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
95.
Synthetic cyclic peptides and methods of preparation and use thereof
The present invention relates, in part, to novel compounds comprising 4-imidazolidinone-fused cyclic peptides and compositions thereof. The present invention also relates to methods of generating said compounds and compositions thereof as well as methods of inhibiting protein-protein interaction using said compounds or compositions thereof. In another aspect, the present invention relates, in part, to methods of treating or preventing a various diseases or disorders using said compounds or compositions thereof.
Described herein DNA-based assays that include nanostructures providing a simple, highly sensitive method for small molecule, biologic and peptide measurements that are optimized for use in a commercial, point-of-care diagnostic settings and systems. These DNA- based assays may include a combination of multiple redox molecules (e.g., methylene blue) such as between 3-8 redox molecules, and a spacer of between about 2A and 20 A (and in particular between 3A and 8A), that results in an assay that has significantly greater signal and greater sensitivity as compared to prior DNA-based assays.
C12Q 1/6816 - Tests d’hybridation caractérisés par les moyens de détection
C12Q 1/6825 - Détecteurs faisant intervenir la détection d’acides nucléiques
97.
Use of pectin or pectin-related saccharides to enhance efficacy of plant growth-promoting rhizobacteria (PGPR) strains for promoting growth and health in plants and animals
Disclosed are compositions and methods that include or utilize plant growth promoting rhizobacteria (PGPR) for improving growth and health in plants and animals. The compositions and methods include or utilize a plant growth promoting rhizobacteria (PGPR) that expresses a protein associated with pectin metabolism, and a saccharide comprising pectin or a pectin-related saccharide.
A01H 3/00 - Procédés de modification des phénotypes
A23K 10/18 - Ajout de micro-organismes ou de leurs produits d’extraction, p. ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires de micro-organismes vivants
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p. ex. pour les poissons, les crustacés ou les mollusques
A61K 31/7004 - Monosaccharides ayant uniquement des atomes de carbone, d'hydrogène et d'oxygène
A61K 35/742 - Bactéries sporulées, p. ex. Bacillus coagulans, Bacillus subtilis, clostridium ou Lactobacillus sporogenes
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
A high-friction road patch may comprise an aggregate capable of providing sufficient friction between a road surface and vehicle wheel. In some embodiments, the patch may comprise a waterproof, asphalt overlay with a first layer of cured bitumen and calcined bauxite aggregate particles, a second layer of viscous bitumen and a reinforcement component, and a binder layer for bonding the overlay with the road surface. The resulting product may provide a sufficient skid resistance value in an overlay that is far less susceptible to or incapable of debonding as with prior art solutions.
E01C 23/10 - Dispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour relever ou remettre à niveau les revêtements affaissésDispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour combler les vides sous le revêtementDispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés pour introduire des matériaux dans la substructure
E01C 21/00 - Appareils ou procédés pour la stabilisation de la surface pour la construction des routes ou à des fins analogues, p. ex. en mélangeant des agrégats d'emprunt à un liant
E01C 23/06 - Dispositifs ou aménagements pour travailler la surface terminéeDispositifs pour réparer la surface des revêtements endommagés
E01C 5/12 - Revêtements faits d'éléments préfabriqués faits d'éléments et de liants bitumeux
A high-friction road patch may comprise an aggregate capable of providing sufficient friction between a road surface and vehicle wheel. In some embodiments, the patch may comprise a waterproof, asphalt overlay with a first layer of cured bitumen and calcined bauxite aggregate particles, a second layer of viscous bitumen and a reinforcement component, and a binder layer for bonding the overlay with the road surface. The resulting product may provide a sufficient skid resistance value in an overlay that is far less susceptible to or incapable of debonding as with prior art solutions.
The present technology provides a nanopore electrode sequencer for the characterization and sequencing of biomolecules. Two or more ultrathin MXene sheets containing nanopores serve as electrodes that bind and store cations which can be released to provide ionic current through the nanopore during sequencing, thereby eliminating access resistance to ions at the entrance to the nanopore from bulk solution. Resolution of ionic current changes caused by biopolymer components within the nanopore is thereby substantially improved, providing more sensitive and robust sequencing of biopolymers.