The present invention relates to a process for producing alkyl-pyridine N-oxides of formula (I) from the corresponding unsubstituted 3-alkyl pyridines or the 5-alkyl pyridines of formula (II) correspondingly substituted in 2-position, in the presence of at least one oxidant, water, organic solvent and catalyst.
C07D 213/127 - Preparation from compounds containing pyridine rings
C07D 213/89 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
The invention relates to mixtures of propoxylated 4-toluidines containing two or more different di- or tri-propoxy lated or higher propoxylated p-toluidines in specific weight ratios, to methods for preparing them and to their use as polymerization accelerators or vulcanization accelerators or as hardener components in epoxy resins.
C07C 215/08 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
C08G 59/56 - Amines together with other curing agents
The invention relates to an improved method for producing mixtures containing 2-(2-hydroxyethyl)-piperidinyl carbamide acid secondary butyl ester from a raw product by means of a thermal treatment with short dwell times, to devices for said method, to the use of such devices for such methods, and to the mixtures according to the invention which can be obtained using the method.
A01N 47/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
B01D 3/00 - Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
C10G 70/04 - Working-up undefined normally gaseous mixtures obtained by processes covered by groups , , , , by physical processes
The invention relates to an improved method for producing mixtures containing 2-(2-hydroxyethyl)-piperidinyl carbamide acid secondary butyl ester from a raw product by means of a thermal treatment with short dwell times, to devices for said method, to the use of such devices for such methods, and to the mixtures according to the invention which can be obtained using the method.
A01N 47/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
C10G 70/04 - Working-up undefined normally gaseous mixtures obtained by processes covered by groups , , , , by physical processes
B01D 3/00 - Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
5.
IMPROVED PROCESS FOR PREPARING UNSYMMETRICAL DIALKYL SULFIDES
The invention relates to an improved process for preparing unsymmetrical dialkyl sulfides by reacting a monoalkyl sulfide with at least one alkyl halide in the presence of base.
The invention relates to an improved process for preparing bromochloromethane by reacting dichloromethane and dibromomethane in the presence of catalysts.
The invention relates to an improved process for preparing cyclopropyl compounds from alkenes through reaction of the alkene in the presence of bromochloromethane, elemental zinc, and elemental copper or copper compounds (cyclopropanation reaction).
C07C 29/44 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by addition reactions, i.e. reactions involving at least one carbon-to-carbon double or triple bond
8.
Improved process for preparing epoxides from aldehydes or ketones
The invention relates to an improved process for preparing epoxides from aldehydes or ketones by reacting a ketone or aldehyde with at least one sulfonium salt, and to sulfonium salts that may be used in the process of the invention.
The present invention relates to a method for preparing 2-alkoxy-4-amino-5-methylpyridines of the formula (I) and/or 2-alkoxy-4-alkylamino-5-methylpyridines of the formula (II) from the corresponding 2-haloaminopyridines and the appropriate alcohols in the presence of base, and to the compounds resulting therefrom.
The invention relates to mixtures of propoxylated 4-toluidines containing two or more different di- or tri-propoxylated or higher propoxylated p-toluidines in specific weight ratios, to methods for preparing them and to their use as polymerization accelerators or vulcanization accelerators or as hardener components in epoxy resins.
C07C 215/68 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
C07C 217/50 - Ethers of hydroxy amines of undetermined structure, e.g. obtained by reactions of epoxides with hydroxy amines
C08G 65/26 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
11.
IMPROVED PROCESS FOR PREPARING UNSYMMETRICAL DIALKYL SULFIDES
The invention relates to an improved process for preparing unsymmetrical dialkyl sulfides by reacting a monoalkyl sulfide with at least one alkyl halide in the presence of a base.
The invention relates to an improved process for preparing unsymmetrical dialkyl sulfides by reacting a monoalkyl sulfide with at least one alkyl halide in the presence of a base.
The invention relates to an improved process for preparing bromochloromethane by reacting dichloromethane and dibromomethane in the presence of catalysts.
The invention relates to an improved process for preparing bromochloromethane by reacting dichloromethane and dibromomethane in the presence of catalysts.
The invention relates to an improved process for preparing epoxides from aldehydes or ketones by reacting a ketone or aldehyde with at least one sulfonium salt, and to sulfonium salts that can be used in the process according to the invention.
The invention relates to an improved process for preparing cyclopropyl compounds from alkenes by reacting the alkene in the presence of bromochloromethane, elemental zinc and elemental copper or copper compounds (cyclopropanation reaction).
C07C 29/44 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by addition reactions, i.e. reactions involving at least one carbon-to-carbon double or triple bond
C07C 33/50 - Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
17.
IMPROVED PROCESS FOR PREPARING EPOXIDES FROM ALDEHYDES OR KETONES
The invention relates to an improved process for preparing epoxides from aldehydes or ketones by reacting a ketone or aldehyde with at least one sulfonium salt, and to sulfonium salts that can be used in the process according to the invention.
The invention relates to an improved process for preparing cyclopropyl compounds from alkenes by reacting the alkene in the presence of bromochloromethane, elemental zinc and elemental copper or copper compounds (cyclopropanation reaction).
C07C 29/44 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by addition reactions, i.e. reactions involving at least one carbon-to-carbon double or triple bond
C07C 33/50 - Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
19.
IMPROVED PROCESS FOR PREPARING 4,6-DIHYDROXYPYRIMIDINE
The method relates to a process for preparing 4,6-dihydroxypyrimidine by reacting malonic acid esters of formula (II) with a formic acid derivative of formula (III) in the presence of an alkaline metal alcoholate of formula (I) at an elevated temperature. The condensation product formed in this way is crystallized after having been brought into contact with acid. After phase separation and distillation, the alcohol of formula (V) is recovered from the two-phase filtrate resulting from this process, which alcohol can be used for preparing the alkaline metal alcoholate of formula (I).
The invention relates to a process for preparing 2-alkoxy-4-amino-5-methyl-pyridines of the formula (I) and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines of the formula (II) from the corresponding 2-halogen-amino-pyridines and the corresponding alcohols in the presence of a base, and to the corresponding resulting compounds.
The present invention relates to a process for preparing 2-haloacrylic esters from 2-hydroxymethyl- or 2-halomethyl- or 2-chlorosulfinyloxymethyl-2-halomalonic diesters. The invention further provides novel 2-halomethyl-2-halomalonic diesters or 2-chlorosulfinyloxymethyl-2-halomalonic diesters which can be used for preparation of the 2-haloacrylic esters.
C07C 51/00 - Preparation of carboxylic acids or their salts, halides, or anhydrides
C07C 69/63 - Halogen-containing esters of saturated acids
C07C 67/287 - Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of halogenPreparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by substitution of halogen atoms by other halogen atoms
22.
METHOD FOR PRODUCING 2-HALOGEN-ACRYLIC ACID ESTERS
The invention relates to a method for producing 2-halogen-acrylic acid esters from 2-hydroxymethyl- or 2-halogen-methyl- or 2-chlorosulfinyloxymethyl-2-halogen-malonic acid diesters. The invention further relates to 2-halogen-methyl-2-halogen-malonic acid diesters or 2-chlorosulfinyloxymethyl-2-halogen-malonic acid diesters of a new type, which can be used to produce the 2-halogen-acrylic acid esters.
C07C 67/307 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogenPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by substitution of halogen atoms by other halogen atoms
Disclosed is a method for producing 2, 3-dichlorpyridine, in which compounds of formula (I) (R-N=CHCH3) are reacted with chloroacetic acid anhydride or chloroacetic acid chloride into an N-ethenyl chloroacetic amide of formula (II), which is then allowed to react with a chlorination reagent and a Vilsmeier reagent into a 2, 3-dichloropyridinium chloride compound of formula (IV), from which the 2, 3-dichloropyridine is released by heat.
The invention relates to a method for producing ortho-acylated aromatic or heteroaromatic carboxylic acids. According to the method, an aromatic or hetero-aromatic carboxylic acid or anhydride thereof, each of which has a CH group at the ortho position for a carboxylate function, is reacted with an acylation reagent in the presence of a rhodium catalyst and a basic additive.
C07C 51/083 - Preparation of carboxylic acids or their salts, halides, or anhydrides from carboxylic acid anhydrides
C07C 51/373 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
C07C 65/34 - Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
25.
SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING
A method is described for linking carbon-carbon bonds by reacting carbonic acid salts with aryl, heteroaryl or vinyl alkyl sulphonates such as methane sulphonates, releasing carbon dioxide, in the presence of a bimetallic catalyst system with benzimidazolyl phosphine compounds as ligands. The invention also relates to the benzimidazolyl phosphine compounds, corresponding metal complexes and catalysts per se.
C07F 9/6506 - Five-membered rings having the nitrogen atoms in positions 1 and 3
C07C 333/08 - Monothiocarbamic acidsDerivatives thereof having nitrogen atoms of thiocarbamic groups bound to carbon atoms of six-membered aromatic rings
C07D 333/54 - Benzo [b] thiophenesHydrogenated benzo [b] thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
C07D 209/08 - IndolesHydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
C07D 307/79 - Benzo [b] furansHydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
C07D 201/12 - Preparation of lactams by depolymerising polyamides
26.
METHOD FOR PRODUCING ASYMMETRIC (THIO)PHOSPHORIC ACID TRIAMIDES
The invention relates to a method for producing asymmetric (thio)phosphoric acid triamides from (thio)phosphoric acid trichloride and primary amines and ammonia, which can also be carried out in the multi-purpose stirred tank system used in fine chemicals. Compared to conventional methods, smaller amounts of ammonia residue are required and the desired compounds are obtained in good yields, high purity and high space-time yields.
C07C 67/317 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groupsPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenolysis of functional groups
C07C 67/307 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogenPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by substitution of halogen atoms by other halogen atoms
28.
INSECT-REPELLING FORMULATIONS OF SUN SCREENS, METHOD FOR PRODUCING SAME AND USE THEREOF FOR THE PROTECTION FROM UV LIGHT AND INSECT BITES
The invention relates to insect-repelling formulations of a sun screen, containing the insect repellents 1-sec-butyloxycarbonyl-2-(2-hydroxyethyl)-piperidine (Saltidin®) and 2,2r-[6-(4-methoxyphenyl)-1,3,5-triazine-2,4-diyl]bis{5-[(2-ethylhexyl)oxy]phenol}, and titanium dioxide or zinc oxide as sun screens. The invention also relates to a method for producing said formulations and to the use thereof for the protection from UV light and insect bites.
A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
A61Q 17/02 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
29.
PROCESS FOR PREPARING AZOMETHINES FROM ALPHA-OXOCARBOXYLATES, AMINES AND ARYL BROMIDES
A process for preparing azomethines of the general formula (V) where R is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms, and R1 is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms, R2 is hydrogen or an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted cycloalkyl radical or an optionally substituted heteroaromatic radical having 5 to 24 carbon atoms by reacting alpha-oxo carboxylates of the general formula (I) where n is a number in the range from 1 to 6, M(n+) is a cation, with aryl bromides of the general formula (IV) and amines of the general formula (II) via the alpha-iminocarboxylate intermediate of the general formula (III), in the presence of two transition metals or compounds thereof as catalyst, is described.
C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
C07C 319/24 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
C07D 213/127 - Preparation from compounds containing pyridine rings
What are described are insect- and mite-repellent compositions comprising at least 2 enantiomers selected from the group of 1-[(S)-sec-butyloxycarbonyl]-2-(S)-(2-hydroxyethyl)piperidine (referred to hereinafter as S,S), 1-[(R)-sec-butyloxycarbonyl]-2-(R)-(+)-(2-hydroxyethyl)piperidine (referred to hereinafter as R,R), 1-[(S)-sec-butoxycarbonyl]-2-(R)-(+)-(2-hydroxyethyl)piperidine (referred to hereinafter as S,R), 1-[(R)-sec-butyloxycarbonyl]-2-(S)-(+)-(2-hydroxyethyl)piperidine (referred to hereinafter as R,S), excluding the racemate mixture thereof, a process for preparation thereof and the use thereof in insect- and mite-repellent formulations.
The invention relates to a method for producing organic compounds of the general formula (I) R-R' (I), by reacting a corresponding compound of the general formula (II) R-X (H), where X stands for fluorine, chlorine, bromine, or iodine, forming a magnesium organic compound of the general formula (III) [M+]n [RmMgXkY1] (III), compounds of the formula (III) being reacted with a compound of the general formula (IV), characterized in that the reaction of (III) with (IV) is performed in the presence of a) catalytic quantities of an iron compound, relative to the compound of the general formula (II), and optionally in the presence b) of an additive comprising nitrogen, oxygen, and/or phosphorous in a catalytic or stoichiometric quantity relative to the compound of the general formula (II).
C07C 1/32 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero atoms other than, or in addition to, oxygen or halogen
C07C 15/44 - Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic part substituted by unsaturated hydrocarbon radicals monocyclic the hydrocarbon substituent containing a carbon-to-carbon double bond
C07C 43/205 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
33.
PREPARATION OF SUBSTITUTED 2-FLUOROACRYLIC ACID DERIVATIVES
C07C 67/307 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogenPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by substitution of halogen atoms by other halogen atoms
C07C 67/317 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groupsPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenolysis of functional groups
C07C 69/63 - Halogen-containing esters of saturated acids
34.
PREPARATION OF SUBSTITUTED 2-FLUOROACRYLIC ACID DERIVATIVES
The present describes a process for preparing substituted 2-fluoroacrylic acid derivatives of formula I (see formula I) by reacting compounds of formula II (see formula II) where X is a CI, Br, I or a pseudohalogen with at least one base in the presence of at least one polymerization inhibitor, that are starting materials in the synthesis of polymers used as plastics in optical wavelengths and as polymeric additives in medicaments.
C07C 67/317 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groupsPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenolysis of functional groups
C07C 67/307 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogenPreparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by substitution of halogen atoms by other halogen atoms
C07C 69/63 - Halogen-containing esters of saturated acids
The present invention relates to a process for preparing monomethylhydrazine by methylating hydrazine or hydrazinium hydrochloride or hydrazinium dihydrochloride with methyl chloride and/or a methano/HCl mixture, characterized in that the reaction mixture formed in the methylation is reacted with an organic base from the group of the alkylamines or alkanolamines and monomethylhydrazine is removed by distillation from the reaction mixture in a low boiler fraction and the low boiler fraction is optionally subjected to a further distillation.
What is described is a process for preparing 2-hydroxyacetals of the general formula in which R1 is hydrogen, a branched or unbranched C1-C12-alkyl radical, an electron-deficient, halogen-, NO2-, CN-, CF3-, acyl group- or branched or unbranched alkyl group-substituted or unsubstituted C5-C6-aryl or heteroaryl, and R2 is a branched or unbranched C1-C5-alkyl radical, or both R2 radicals are bonded directly to one another or to one another via a C1-C4 unit, by reacting an enol compound of the general formula (II) in which R3 is the same and R1 is as defined for formula (Ia), with bromine to give the corresponding dibromo adduct and then reacting this dibromo adduct with an alkoxide of the general formula (III) M-O-R2 (III) in which R2 is as defined for formula (Ia) and O is oxygen and M is lithium, sodium or potassium. What is likewise described is the preparation of the corresponding 2-hydroxyalkanals from the 2-hydroxyacetals thus obtained by acidic hydrolysis.
C07C 41/50 - Preparation of compounds having groups by reactions producing groups
C07C 43/315 - Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
C07C 67/287 - Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of halogenPreparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by substitution of halogen atoms by other halogen atoms
C07C 69/003 - Esters of saturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
37.
METHOD OF PRODUCING 2-PHENOXYACETALS AND THE CORRESPONDING 2-PHENOXY-CARBALDEHYDES THEREFROM
A method of producing 2-phenoxyacetals of the general formula (Ia) is likewise described in which R1 is hydrogen, a branched or unbranched C1-C12-alkyl moiety, a low-electron, halogen-NO2-, -CN, -CF3-, acyl- or branched or unbranched alkyl-substituted or unsubstituted C5-C6-aryl or heteroaryl moiety and R2 is a branched or unbranched C1-C5-alkyl moiety or both R2 moieties are directly linked to one another or via a C1-C4 unit, one Y is always hydrogen and the other Y is an -NO2, -CN or -CF3 moiety or fluorine or chlorine or both Y moieties each independently of one another are an NO2-, CN- or CF3-moiety or fluorine or chlorine, Z is hydrogen or an -NO2 moiety or branched or unbranched C1-C6-alkyl moiety or acyl moiety, by reacting a 2-hydroxyacetal compound of the general formula (II) in which R1 and R2 have the meaning given for formula (Ia) with a substituted aromatic of the general formula (III) in which Y has the meaning given for formula (I) and Y is fluorine, chlorine, bromine or an NO2 group, in the presence of a base. A method of producing the corresponding 2-phenoxycarbaldehydes by acid hydrolysis of the 2-phenoxyacetals is likewise described.
C07C 205/37 - Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
C07C 201/12 - Preparation of nitro compounds by reactions not involving the formation of nitro groups
38.
METHOD FOR THE PRODUCTION OF SUBSTITUTED HETEROAROMATES
The invention relates to a method for the production of substituted heteroaromates of the general formula (I), where X denotes oxygen, sulfur, or NR5 where R5 indicates hydrogen, C1-C20 alkyl or C5-C6 aryl and R4 indicates C1-C20 alkyl, C5-C6 aryl or heteroaryl, R1, R2, and R3 denote hydrogen, halogen, C1-C20 alkyl, C5-C6 aryl or heteroaryl, by conversion A) of a halogenated heteroaromate of the general formula (II), where X denotes the meaning stated for formula (I), and R6 denotes bromine, iodine, or chlorine, and R1, R2, and R3 have the meaning stated for formula (I), with a Grignard reagent of the general formula (III), where R4 has the meaning stated for formula (I), and Hal is bromine, iodine, or chlorine, or B) by conversion of the halogenated heteroaromate of the formula (II) with magnesium, initially to a Grignard compound of the general formula (IIIa), where Hal is bromine, iodine, or chlorine, and X and R1, R2, and R3 have the meaning stated for formula (I), and further conversion using a halogenated compound of the general formula (IV), where R4 has the meaning stated for formula (I), and Hal is bromine, iodine, or chlorine, the conversions A) or B) each being carried out in the presence of a Ni or Pd catalyst, characterized in that the method is carried out in the presence of cycloalkyl alkyl ether as the solvent, and possibly a further solvent. The invention further describes the use of cycloalkyl alkyl ether, particularly cyclopentyl methyl ether, in the Kumada reaction for the production of substituted heteroaromates, particularly of substituted thiophenes.
The invention relates to an improved method for producing carbonate-terminated compounds using amines. The method according to the invention is characterized by high yields with no phenol being produced as a secondary component.
The invention relates to an improved method for producing carbonate-terminated urethanes using di- or polyisocyanates. The method according to the invention is characterized by high yields with no phenol being produced as a secondary component.
C08G 18/28 - Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
C08G 18/77 - Polyisocyanates or polyisothiocyanates having hetero atoms in addition to the isocyanate or isothiocyanate nitrogen and oxygen or sulfur
The invention relates to an improved method for producing carbonate-terminated urethanes using isocyanates. The method according to the invention is characterized by high yields with no phenol being produced as a secondary component.
C07C 269/02 - Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups from isocyanates with formation of carbamate groups
C07C 271/08 - Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
42.
2-NITRO-5-FLUORO-3',4'-DICHLOROBIPHENYL AND METHOD FOR THE PRODUCTION THEREOF
A method is disclosed for producing 2-nitro-5-fluoro-3',4'-dichlorobiphenyl by decarboxylizing C-C linkage. The method relates to a decarboxylizing cross-coupling of 2-nitro-5-fluorobenzoic acid salts with 1-bromine-3,4-dichlorobenzol, wherein the catalyst comprises two transition metals or transition metal compounds, one of which preferably being present in oxidation stages differing from one another by one unit and thus catalyzing a radical decarboxylization, and the second preferably receiving oxidation stages differing from one another by two units and thus catalyzing the two-electron processes of a cross-coupling reaction.
C07C 201/12 - Preparation of nitro compounds by reactions not involving the formation of nitro groups
C07C 205/12 - Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
C07C 209/36 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings
C07C 211/52 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
B01J 31/26 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups
B01J 31/18 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony
C07C 201/08 - Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
C07C 205/06 - Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to carbon atoms of six-membered aromatic rings
C07C 205/12 - Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
C07C 205/37 - Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
C07C 205/38 - Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. nitrodiphenyl ethers
A process for preparing polyfunctional amines of the formulae (I) or (II) by hydrogenating the corresponding nitriles of the formulae (III) or (IV) with hydrogen, characterized in that a melt, solution or suspension of the nitrile of the formula (I) or (II) is added over the course of the reaction time to a suspension or solution of a catalyst in a solvent which comprises ammonia and optionally other additives at a temperature in the range from 60 to 150°C, and is stirred under hydrogen pressure.
C07C 209/48 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
C07C 211/14 - Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
A process is described for preparing polyfunctional amines of formula (I) and (II) by hydrogenating the corresponding nitriles of formula (III) or (IV) with hydrogen, characterized in that a melt, solution or suspension of the nitrile of the formula (I) or (II) is added over the course of the reaction time to a suspension or solution of a catalyst in a solvent which comprises ammonia and optionally other additives, and is stirred at a temperature in the range from 60 to 150°C under hydrogen pressure.
C07C 209/48 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
C07C 211/14 - Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
46.
METHOD FOR THE HOMOGENEOUSLY CATALYZED PRODUCTION OF TERMINAL GROUP-CAPPED POLYETHERS
The invention provides an improved method for the production of terminal group-capped polyethers using homogeneous catalysis in the presence of Brönstedt acids.
C08G 65/00 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
C08G 65/26 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
The invention provides an improved method for producing menthyl derivatives through the reaction of menthyl halides with magnesium and the subsequent reaction with electrophiles in the presence of additives.
C07C 231/10 - Preparation of carboxylic acid amides from compounds not provided for in groups
C07C 233/58 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
48.
ENANTIOMER-ENRICHED ALPHA-,OMEGA AMINO ALCOHOL DERIVATIVES, THEIR PRODUCTION AND USE AS INSECT- AND MITE-REPELLING AGENTS
The invention relates to an insect- and mite-repelling agent, characterized by a content of at least one substituted, enantiomer-enriched α-,쳱-amino alcohol derivative of formula (1) wherein X represents hydrogen, COR11 or R13, R13 represents C1-C6 alkyI, R1 represents C1-C7 aIkyl, C3-C7 alkenyl or C2-C7 alkinyl, R2, R11, R13 are identical or different and represent C1-C6 alkyl or C2-C7 aIkenyl, R3-R8 are identical or different and represent hydrogen or C1-C6 alkyl, wherein R2 and R3 or R3 and R7 or R3 and R5 or R5 and R7 can also form, together with the atoms to which they are bonded, a 5- or 6-membered monocyclic ring. Also disclosed is a method for producing said agent.
A01N 47/18 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof containing a —O—CO—N group, or a thio-analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
A01N 47/16 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof the nitrogen atom being part of a heterocyclic ring
A01N 47/12 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof containing a —O—CO—N group, or a thio-analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
C07C 269/06 - Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
C07C 271/16 - Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
C07D 207/08 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
C07D 211/22 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulfur atoms by oxygen atoms
C07C 271/24 - Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Chemical products for industrial purposes, namely, active chemical ingredients and solvents for use in the manufacture of insect repellents Insect-repellents
An improved process is provided for preparing menthyl amides by reacting menthyl halides with magnesium or lithium and subsequently reacting with an isocyanate, a heterocycle or a carbamoyl chloride.
C07C 231/10 - Preparation of carboxylic acid amides from compounds not provided for in groups
C07C 233/58 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
A01N 47/18 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof containing a —O—CO—N group, or a thio-analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 47/16 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof the nitrogen atom being part of a heterocyclic ring
A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 47/18 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof containing a —O—CO—N group, or a thio-analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
A01N 47/18 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof containing a —O—CO—N group, or a thio-analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
A01N 47/16 - Carbamic acid derivatives, i.e. containing the group —O—CO—NThio-analogues thereof the nitrogen atom being part of a heterocyclic ring
A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
A01N 37/18 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N, e.g. carboxylic acid amides or imidesThio-analogues thereof
According to the invention, organozink compounds of R1-Ar1-ZnY (1) type are convertible, with different functionalised aryl halides R2-Ar2-X (2) in the presence of Ni or Fe catalytic quantities in a polar solvent or a polar solvent mixture, into a polyfunctional biarylene of R1-Ar1-AR2-R2 (3) type. The type (1) organic compounds are obtainable by a transmetallisation reaction of aryl-magnesium halides or lithium-aryl compounds, for example with ZnBr2.
The present invention relates to the technical purification of vinylene carbonate (VC) by means of a simple thermal treatment with organic compounds which possess amidic nitrogen-hydrogen bonds, followed by a distillation and a melt crystallization. In this way VC of ultra-high purity is obtained. The high-purity vinylene carbonate can be stored and transported without stabilizer.
The present invention relates to the industrial production of vinylene carbonate (VC) by elimination of hydrogen chloride from chloroethylene glycol carbonate (CGC) over solid catalysts in the gas phase, the reaction being carried out over a catalyst bed which is agitated by mixing.
Method of storing and transporting vinylene carbonate, characterized in that the vinylene carbonate possesses a stabilizer content of less than 100 ppm, has a degree of purity of 99.9% to 99.99999%, and is in the solid aggregate state.
The present invention relates to the industrial purification of vinylene carbonate (VC). It has been found advantageous to subject the impure VC, prior to purifying distillation, to a simple thermal treatment with organic compounds which possess amidic nitrogen-hydrogen bonds.
The present invention relates to the industrial production of vinylene carbonate (VC) by elimination of hydrogen chloride from chloroethylene glycol carbonate (CGC) with tertiary amines in the absence of relatively large additional amounts of solvent.
The present invention relates to a new copper-catalysed photochemical cyclisation process for the preparation of bicylic molecules useful as intermediates in the manufacture of drugs. In a preferred aspect, the process of the invention may be used to prepare 3-hydroxy-bicyclo⏧3.2.0]heptane.
C07C 29/56 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by isomerisation
C07C 35/28 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with a hydroxy group on a condensed ring system having two rings the condensed ring system containing seven carbon atoms
The invention relates to a method for producing diarylbenzidines, especially diphenylbenzidines, from the corresponding optionally substituted biphenyldihalogenides and optionally substituted anilins using a base and a catalyst. Said catalyst comprises a palladium compound and a bisaryl-dialkylphosphine.
C07C 209/10 - Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
C07C 211/50 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton with at least two amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
04 - Industrial oils and greases; lubricants; fuels
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Chemicals used in industry, science and photography, as
well as in agriculture, horticulture and forestry;
synthetic resins and plastics in raw state in form of
powders, granules, pastes, emulsions, liquids; manures;
fire extinguishing compositions; tempering and soldering
agents; chemical preparations for keeping fresh and
conserving food; tanning agents; adhesives used in
industry; chemicals used in industry, namely additives for
mineral oils, for technical oils, for lubricants, for
fuels. Dyes, dyestuffs, varnishes, lacquers; preservatives against
rust and against deterioration of wood; colorants;
pigments; mordants; raw natural resins. Technical oils and greases; lubricants; dust absorbing,
wetting and binding compositions; non chemical additives
for mineral oils, for technical oils and greases, for
fuels. Pharmaceutical and veterinary preparations, in particular
pharmaceutical agents for the defence against insects;
insect repellents.
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
04 - Industrial oils and greases; lubricants; fuels
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Chemicals used in industry, science and photography, as well as in agriculture, horticulture and forestry; synthetic resins and plastics in raw state in form of powders, granules, pastes, emulsions, liquids; manures; fire extinguishing compositions; Chemical preparations for keeping fresh and conserving food; tanning agents; adhesives used in industry; chemicals used in industry, namely additives for mineral oils, technical oils and lubricants, fuels. Dyes, dyestuffs, varnishes, lacquers; preservatives against rust and against deterioration of wood; colorants; pigments; mordants; raw natural resins. Technical oils and greases; lubricants; dust absorbing, wetting and binding compositions; additives for mineral, oils, technical oils and greases, fuels. Pharmaceutical and veterinary preparations, in particular pharmaceutical agents for the defense against insects; insect repellents.
