Baden-Württemberg Stiftung gGmbH

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2024 December 2
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IPC Class
B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers 9
B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface 5
B33Y 10/00 - Processes of additive manufacturing 5
B63B 59/04 - Preventing hull fouling 5
F15D 1/00 - Influencing the flow of fluids 5
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Pending 7
Registered / In Force 60

1.

COHERENT SINGLE PHOTON SOURCE

      
Application Number EP2023064304
Publication Number 2024/245528
Status In Force
Filing Date 2023-05-28
Publication Date 2024-12-05
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Kubanek, Alexander
  • Waltrich, Richard
  • Klotz, Marco
  • Bayer, Gregor
  • Berghaus, Robert
  • Antoniuk, Lukas
  • Lettner, Niklas

Abstract

The invention relates to a coherent single photon source (100) comprising: a nanodiamond (120) having a quantum emitter (140), wherein the nanodiamond (120) and the quantum emitter (140) are designed and configured such that the quantum emitter (140) emits coherent, indistinguishable photons (160). The invention further relates to a system (300) comprising: a first coherent single photon source (101); and a second coherent single photon source (102); wherein the first coherent single photon source (101) and the second coherent single photon source (102) are designed and configured such that photons (160) emitted from a first quantum emitter (151) of a first nanodiamond (121) of the first coherent single photon source (101) are indistinguishable from photons (160) emitted from a second quantum emitter (152) of a second nanodiamond (122) of the second coherent single photon source (102).

IPC Classes  ?

  • G02F 1/35 - Non-linear optics
  • C09K 11/65 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing carbon
  • G02B 6/122 - Basic optical elements, e.g. light-guiding paths
  • B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals

2.

QUANTUM MEMORY UNIT AND QUANTUM REGISTER

      
Application Number EP2023085222
Publication Number 2024/245586
Status In Force
Filing Date 2023-12-11
Publication Date 2024-12-05
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Kubanek, Alexander
  • Klotz, Marco
  • Waltrich, Richard
  • Tangemann, Andreas

Abstract

The invention relates to a quantum memory unit (100) comprising: a nanodiamond (120) having a quantum emitter (140), wherein an electron spin of the quantum emitter (140) is coupled to a spin object (170) inside or outside of the nanodiamond (120); wherein a coupling rate of the electron spin to the spin object (170) is larger than a decoherence rate of the electron spin; and wherein the spin object (170) is designed and configured such that quantum information can be stored therein, retrieved from it; and / or that a quantum state of the spin object (170) can be manipulated.

IPC Classes  ?

  • G02F 1/35 - Non-linear optics
  • C09K 11/65 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing carbon
  • G02B 6/122 - Basic optical elements, e.g. light-guiding paths
  • B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
  • G06N 10/00 - Quantum computing, i.e. information processing based on quantum-mechanical phenomena

3.

DEVICE FOR DETECTING AN OBJECT AND/OR FOR DETERMINING A DISTANCE TO AN OBJECT METHOD THEREFORE

      
Application Number 18626536
Status Pending
Filing Date 2024-04-04
First Publication Date 2024-10-10
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor
  • Claus, Daniel
  • Alekseenko, Igor
  • Hausladen, Florian
  • Glöckler, Felix
  • Pedrini, Giancarlo
  • Gröger, Alexander

Abstract

The invention relates to a measuring device and a method for detecting at least one object and/or for determining an object distance, e.g., for use in road traffic. The measuring device can comprise: a light source for emitting light with a predetermined coherence length; a beam splitter for splitting the emitted light into measuring and reference beams; a transfer unit that converts the reference beam into a plurality of sub-reference beams; an image data acquisition unit for acquiring image data resulting from a superposition of the sub-reference beams with an object beam comprising at least a part of the measuring beam that was scattered and/or reflected by the at least one object; and an evaluation unit for evaluating the image data, wherein the reference beam transfer unit comprises spatially separated optical paths having different optical lengths, along which the sub-reference beams are guided to the image data acquisition unit.

IPC Classes  ?

  • G06V 20/58 - Recognition of moving objects or obstacles, e.g. vehicles or pedestriansRecognition of traffic objects, e.g. traffic signs, traffic lights or roads

4.

METHOD AND APPARATUS FOR PROCESS MONITORING DURING PRODUCTION OF A FINISHED PART FROM A HOT-CROSSLINKING MATERIAL IN A PRIMARY SHAPING PROCESS

      
Application Number EP2023067425
Publication Number 2024/003027
Status In Force
Filing Date 2023-06-27
Publication Date 2024-01-04
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Mayer, Dennis
  • Weisser, Dennis
  • Deckert, Matthias

Abstract

The invention relates to a method for process monitoring during production of a finished part (112) in a primary shaping process. The method comprises the following steps: a) providing at least one mould (114) designed for the primary shaping process, wherein the mould (114) has at least one cavity (116) for receiving at least one starting material for the hot-crosslinking material, and wherein an apparatus for determining a mould internal pressure is also integrated into the mould (114); b) heating the mould (114); c) introducing the at least one starting material for the hot-crosslinking material into the cavity (116) under pressure such that the finished part (112) is produced; d) detecting a progression of the mould internal pressure occurring in step c); e) differentiating, at least once or at least twice, the progression of the mould internal pressure in order to determine at least one derivative selected from the group consisting of: the first-order derivative and the second-order derivative; and f) characterising a progression of a chemical crosslinking reaction by means of at least one derivative selected from the group consisting of: the first-order derivative and the second-order derivative.

IPC Classes  ?

  • B29C 45/77 - Measuring, controlling or regulating of velocity or pressure of moulding material
  • B29C 35/02 - Heating or curing, e.g. crosslinking or vulcanising
  • B29C 45/76 - Measuring, controlling or regulating

5.

Flavi-Block: A Pan-Flavivirus Inhibitor

      
Application Number 18248512
Status Pending
Filing Date 2020-10-15
First Publication Date 2023-11-23
Owner Baden-Württemberg Stiftung GmbH (Germany)
Inventor
  • Schindler, Michael
  • Günther, Marcel
  • Hadian, Kamyar
  • Pereira Gondim, Marcos Vinicius
  • Ruetalo Buschinger, Natalia
  • Schorpp, Karl Kenji
  • Wiltzer-Bach, Linda

Abstract

The present invention relates to specific compounds for use in the prevention or treatment of viral infections caused by RNA viruses.

IPC Classes  ?

6.

P38 MAP KINASE INHIBITORS FOR USE IN THE TREATMENT OF COLORECTAL CANCER

      
Application Number EP2023057981
Publication Number 2023/186881
Status In Force
Filing Date 2023-03-28
Publication Date 2023-10-05
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Laufer, Stefan
  • Dauch, Daniel
  • Forster, Michael
  • Haller, Vanessa
  • Harbig, Jule
  • Kudolo, Mark
  • Nahidino, Philipp
  • Pantsar, Tatu
  • Zender, Lars

Abstract

The invention relates to p38 MAP kinase inhibitors of formula (I) as shown in the description for use in the treatment of colorectal cancer. Further, the invention relates to p38 MAP kinase inhibitors specifically mentioned in the description, and a pharmaceutical composition comprising said inhibitors.

IPC Classes  ?

  • A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
  • A61K 31/175 - Amides, e.g. hydroxamic acids having the group N—C(O)—N or N—C(S)—N, e.g. urea, thiourea, carmustine having the group , N—C(O)—N=N— or , e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazonesThioanalogues thereof
  • A61K 31/397 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
  • A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
  • A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
  • A61K 31/5375 - 1,4-Oxazines, e.g. morpholine
  • A61P 35/00 - Antineoplastic agents
  • C07C 13/00 - Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
  • C07D 205/00 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
  • C07D 207/00 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
  • C07D 265/00 - Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms

7.

THERMORESPONSIVE WOUND DRESSING

      
Application Number EP2022081113
Publication Number 2023/134899
Status In Force
Filing Date 2022-11-08
Publication Date 2023-07-20
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Stolz, Benjamin
  • Mülhaupt, Rolf
  • Steinberg, Thorsten

Abstract

The invention relates to thermoresponsive wound dressings having thermally switchable adhesion/de-adhesion, comprising: a carrier material and an adhesive composition applied to a surface of the carrier material, wherein the adhesive composition comprises: at least one vinyl alcohol/copolymer of the below formula (I): wherein x, with respect to any fatty acid unit, independently represents an integer from 10 to 18, wherein the copolymer according to formula (I) is present as a melt at body temperature, which melt adheres to wounds and skin, and when cooled to a temperature above the freezing point of water, the crystallisation of the copolymer according to formula (I) brings about de-adhesion of the wound dressing. The invention further relates to the use of said thermoresponsive wound dressing for wound healing or for protecting skin injuries and skin disorders.

IPC Classes  ?

8.

METHOD FOR PREPARING A STACK OF DIELECTRIC LAYERS ON A SUBSTRATE

      
Application Number 18145444
Status Pending
Filing Date 2022-12-22
First Publication Date 2023-06-22
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor
  • Zhang, Qiaoshuang
  • Lemmer, Ulrich
  • Jin, Qihao

Abstract

A method for preparing a stack of dielectric layer on a substrate. A substrate is provided and a first layer of liquid is printed onto a surface of the substrate. A first dielectric layer is formed by solidifying the first layer of liquid and a second layer of liquid is printed onto the first dielectric layer. A second dielectric layer is formed by solidifying the second layer of liquid. The liquid includes dielectric constituents and the liquid is printed such that droplets having a volume of less than one hundred nanoliters are locally deposited per square millimeter on the surface of the substrate.

IPC Classes  ?

  • B05D 7/00 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
  • G02B 5/08 - Mirrors
  • G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
  • B05D 3/06 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation

9.

GAS-CONTAINING SURFACE COVER, ARRANGEMENT, AND USE

      
Application Number 18153650
Status Pending
Filing Date 2023-01-12
First Publication Date 2023-05-18
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.

IPC Classes  ?

  • B63B 59/04 - Preventing hull fouling
  • F16L 58/02 - Protection of pipes or pipe fittings against corrosion or incrustation by means of internal or external coatings
  • B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
  • C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
  • B32B 3/30 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids characterised by a layer formed with recesses or projections, e.g. grooved, ribbed
  • F15D 1/00 - Influencing the flow of fluids

10.

EPI-X4 BASED PEPTIDES AND DERIVATIVES THEREOF

      
Application Number 17801684
Status Pending
Filing Date 2021-02-26
First Publication Date 2023-04-27
Owner BADEN-WUERTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Muench, Jan
  • Kirchhoff, Frank
  • Harms, Mirja
  • Abadi, Ashraf H.
  • Habib, Monika Maged Wadi
  • Zelikin, Alexander
  • Carmali, Sheiliza
  • Sanchez Garcia, Elsa
  • Sokkar, Pandian

Abstract

A peptide derivative selected from a list of peptide derivatives with a sequence derived from human serum albumin fragment EPI-X4 is provided, which binds to CXCR4 with about 1000-fold stronger efficiency than EPI-X4. The peptide derivatives comprise length variants as well as modifications by length variants, D-amino acids, coupling of fatty acids, cholesterol or polymers, acetyl substitutions of amino groups, amination of carboxyl groups. Further provided are pharmaceutical compositions of the peptide derivative.

IPC Classes  ?

  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
  • C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
  • A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein

11.

OPTICAL DEVICE

      
Application Number EP2021069202
Publication Number 2023/280426
Status In Force
Filing Date 2021-07-09
Publication Date 2023-01-12
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Giessen, Harald
  • Karst, Julian
  • Hentschel, Mario

Abstract

The present invention relates to an optical device (1), having ˗ at least one first surface (3) comprising at least one first nanostructure (5), wherein ˗ the at least one first nanostructure (5) comprises at least one conductive polymer material, wherein ˗ the optical device (1) comprises at least one conductor (7) in electrical contact to the at least one first nanostructure (5), wherein ˗ the at least one first nanostructure (5) is adapted to change its dielectric function when an electric quantity of the at least one conductor (7) is changed.

IPC Classes  ?

  • G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
  • G02B 5/00 - Optical elements other than lenses
  • G02F 1/17 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on variable-absorption elements not provided for in groups

12.

SYSTEM FOR MONITORING THREE-DIMENSIONAL CELL CULTURES

      
Application Number EP2021076162
Publication Number 2022/083964
Status In Force
Filing Date 2021-09-23
Publication Date 2022-04-28
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Weltin, Andreas
  • Dornhof, Johannes
  • Kieninger, Jochen
  • Maurer, Jochen
  • Urban, Gerald

Abstract

The present invention relates to a system for monitoring (the metabolism of) three-dimensional cell cultures, an organ-on-chip device comprising the system, and a method for monitoring (the metabolism of) cell cultures, preferably three-dimensional cell cultures.

IPC Classes  ?

  • C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
  • C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
  • G01N 33/487 - Physical analysis of biological material of liquid biological material

13.

FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR

      
Application Number EP2020079010
Publication Number 2022/078602
Status In Force
Filing Date 2020-10-15
Publication Date 2022-04-21
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Schindler, Michael
  • Günther, Marcel
  • Hadian, Kamyar
  • Laufer, Stefan
  • Pereira Gondim, Marcos Vinicius
  • Ruetalo Buschinger, Natalia
  • Schorpp, Karl Kenji
  • Wiltzer-Bach, Linda

Abstract

The present invention relates to compounds according to Formula (I) for use in the prevention or treatment of viral infections caused by RNA viruses.

IPC Classes  ?

14.

EPI-X4 BASED PEPTIDES AND DERIVATIVES THEREOF

      
Application Number EP2021054794
Publication Number 2021/170782
Status In Force
Filing Date 2021-02-26
Publication Date 2021-09-02
Owner
  • UNIVERSITÄT ULM (Germany)
  • BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
  • GERMAN UNIVERSITY IN CAIRO (Egypt)
  • AARHUS UNIVERSITY (Denmark)
  • UNIVERSITÄT DUISBURG-ESSEN (Germany)
Inventor
  • Münch, Jan
  • Kirchhoff, Frank
  • Harms, Mirja
  • Abadi, Ashraf H.
  • Habib, Monika Maged Wadie
  • Zelikin, Alexander
  • Carmali, Sheiliza
  • Sanchez Garcia, Elsa
  • Sokkar, Pandian

Abstract

A peptide derivative selected from a list of peptide derivatives with a sequence derived from human serum albumin fragment EPI-X4 is provided, which binds to CXCR4 with about 1000-fold stronger efficiency than EPI-X4. The peptide derivatives comprise length variants as well as modifications by length variants, D-amino acids, coupling of fatty acids, cholesterol or polymers, acetyl substitutions of amino groups, aminations of carboxyl groups. Further provided are pharmaceutical compositions of the peptide derivative.

IPC Classes  ?

  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • A61K 38/00 - Medicinal preparations containing peptides

15.

ACTUATABLE OPTICAL DEVICE, METHOD OF FABRICATING THE DEVICE, AND USE OF A MAGNETIC SUBSTANCE

      
Application Number 17151910
Status Pending
Filing Date 2021-01-19
First Publication Date 2021-07-22
Owner Baden-Wuerttemberg Stiftung gGmbH (Germany)
Inventor
  • Thiele, Simon
  • Jung, Chris
  • Giessen, Harald
  • Herkommer, Alois M.

Abstract

The invention relates to a 3D-printed actuatable optical device and a method for fabricating the actuatable optical device. The method comprises the following steps: forming a three-dimensional structure (50) of the optical device (100) with the aid of a 3D printer in such a way that the three-dimensional structure (50) has: at least one optical element, and at least one microfluidic cavity (4) for accommodating a magnetic substance (6); filling the at least one microfluidic cavity (4) with the magnetic substance (6). The invention relates to a 3D-printed actuatable optical device and a method for fabricating the actuatable optical device. The method comprises the following steps: forming a three-dimensional structure (50) of the optical device (100) with the aid of a 3D printer in such a way that the three-dimensional structure (50) has: at least one optical element, and at least one microfluidic cavity (4) for accommodating a magnetic substance (6); filling the at least one microfluidic cavity (4) with the magnetic substance (6). The invention further relates to the use of a magnetizable fluid for fabricating a magnetically actuatable optical device.

IPC Classes  ?

  • B29C 64/268 - Arrangements for irradiation using laser beamsArrangements for irradiation using electron beams [EB]
  • B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
  • B29C 64/135 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask the energy source being concentrated, e.g. scanning lasers or focused light sources
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

16.

NOVEL DIAGNOSTIC MARKER FOR CREUTZFELDT-JAKOB DISEASE AND ALZHEIMER'S DISEASE

      
Application Number EP2020072559
Publication Number 2021/028452
Status In Force
Filing Date 2020-08-12
Publication Date 2021-02-18
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Otto, Markus

Abstract

The present invention relates to method of diagnosis of diseases associated with synaptic degeneration, in particular of Creutzfeldt-Jakob-Disease or Alzheimer's Disease, and to the use of β-synuclein as a biomarker for diagnosing or assessing the status of diseases associated with synaptic degeneration, in particular of Creutzfeldt-Jakob-Disease or Alzheimer's Disease..

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

17.

Structured gas-containing surfaces

      
Application Number 16982321
Grant Number 12000417
Status In Force
Filing Date 2019-04-11
First Publication Date 2021-02-04
Grant Date 2024-06-04
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to structured, gas-holding surfaces for improving the friction-reducing properties of gas layers held under a liquid and for the simultaneous suppression of turbulence. The present invention furthermore relates to a device comprising this structured, gas-holding surface and to the use of this structured, gas-holding surface.

IPC Classes  ?

  • F15D 1/00 - Influencing the flow of fluids
  • B08B 17/06 - Preventing deposition of fouling or of dust by giving articles subject to fouling a special shape for arrangement
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B63B 59/04 - Preventing hull fouling

18.

Gas-containing surface cover, arrangement, and use

      
Application Number 16815696
Grant Number 11584490
Status In Force
Filing Date 2020-03-11
First Publication Date 2020-07-09
Grant Date 2023-02-21
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.

IPC Classes  ?

  • B63B 59/04 - Preventing hull fouling
  • F16L 58/02 - Protection of pipes or pipe fittings against corrosion or incrustation by means of internal or external coatings
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B32B 3/30 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids characterised by a layer formed with recesses or projections, e.g. grooved, ribbed
  • B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
  • A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
  • C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
  • F15D 1/00 - Influencing the flow of fluids
  • F16L 57/06 - Protection of pipes or objects of similar shape against external or internal damage or wear against wear
  • B05D 5/02 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a matt or rough surface

19.

Method of fabricating an imaging system and corresponding imaging system

      
Application Number 16632241
Grant Number 11536882
Status In Force
Filing Date 2017-07-18
First Publication Date 2020-05-28
Grant Date 2022-12-27
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Thiele, Simon
  • Giessen, Harald
  • Pruss, Christof
  • Herkommer, Alois

Abstract

A method of fabricating an imaging system as well as to a corresponding imaging system. The method includes providing a substrate; and forming, by means of a 3D-printing technique, a 3D structure on the substrate, wherein the forming of the 3D structure includes forming a stack of at least two diffractive optical elements in a single printing step.

IPC Classes  ?

20.

HAND EXOSKELETON

      
Application Number EP2019081497
Publication Number 2020/104328
Status In Force
Filing Date 2019-11-15
Publication Date 2020-05-28
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Eckstein, Jonathan
  • Kemter-Esser, Karoline

Abstract

The invention relates to a hand exoskeleton (10) for supporting the functionality of a hand, having: a flexible mounting module (16), which can be arranged on the back of the hand; and a plurality of finger modules (12), which can be connected to the mounting module (16), wherein each finger module of the plurality of finger modules (12) is designed to receive a corresponding finger of the hand, at least in sections; wherein the mounting module (16) furthermore has: a plurality of connection sections (54) for connecting the plurality of finger modules (12) to the mounting module (16), wherein a respective finger module of the plurality of finger modules (12) is connected to a corresponding connection section of the plurality of connection sections (54); and wherein the mounting module (16) is designed such that the connection sections are movable relative to each other.

IPC Classes  ?

  • A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces

21.

DETERMINING VERSION INFORMATION OF A NETWORK SERVICE

      
Application Number EP2019081175
Publication Number 2020/099485
Status In Force
Filing Date 2019-11-13
Publication Date 2020-05-22
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Armknecht, Frederik
  • Gorke, Christian

Abstract

Aspects of the application relate to a computer-implemented method, a computer program and a network security tool. The computer-implemented method is for determining version information of a network service. The method comprises providing a plurality of specified queries, and receiving an identifier of the network service. The method further comprises retrieving, using the identifier, a first one of the specified queries. The method further comprises querying the network service via the first specified query, wherein the first specified query includes a first task. The method further comprises receiving a response to the first specified query, and determining, based on the response, a first result indication that indicates whether the first task has been successfully carried out. The method further comprises determining first version information of the network service based on the first result indication, and providing the version information of the network service. The version information includes the first version information.

IPC Classes  ?

  • G06F 21/57 - Certifying or maintaining trusted computer platforms, e.g. secure boots or power-downs, version controls, system software checks, secure updates or assessing vulnerabilities
  • H04L 29/06 - Communication control; Communication processing characterised by a protocol

22.

Area scanning confocal microscopy (ASCM)

      
Application Number 16598814
Grant Number 11119299
Status In Force
Filing Date 2019-10-10
First Publication Date 2020-04-16
Grant Date 2021-09-14
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Luo, Ding

Abstract

An area scanning confocal microscope includes a pattern generation unit configured to generate or produce a line pattern comprising a plurality of lines, for example a plurality of straight parallel lines; a projection unit comprising a microscope objective configured to project the line pattern onto an object through the microscope objective, wherein the focal plane in which the line pattern is projected or imaged is tilted at a tilting angle with respect to an optical axis of the microscope, the tilting angle being equal to or greater than 0° and smaller than 90°, for example between 30° and smaller than 85°; and an imaging unit comprising a two-dimensional image detector configured to capture within one image frame of the image detector an image of the projected line pattern.

IPC Classes  ?

  • H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
  • G02B 21/00 - Microscopes

23.

expedition d - Digitale Technologien | Anwendungen | Berufe

      
Application Number 018176741
Status Registered
Filing Date 2020-01-08
Registration Date 2020-05-22
Owner Baden-Württemberg Stiftung gGmbH (Germany)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 16 - Paper, cardboard and goods made from these materials
  • 41 - Education, entertainment, sporting and cultural services

Goods & Services

Compact discs; DVDs; Digital recording media; Data carriers; The aforesaid goods including for information material relating to: digitisation including digitisation in teaching, and in schools and education. Printed matter; Photographs; Instructional and teaching material (except apparatus); The aforesaid goods including for information material relating to: digitisation including digitisation in teaching, and in schools and education. Education; Providing of training; Entertainment; Arranging and conducting events; Publication of information, other than for advertising purposes; Providing of electronic, non-downloadable publications for information purposes; The aforesaid service including in the field: digitisation including digitisation in teaching, and in schools and education.

24.

COACHING4FUTURE

      
Application Number 018161521
Status Registered
Filing Date 2019-12-06
Registration Date 2020-05-22
Owner Baden-Württemberg Stiftung gGmbH (Germany)
NICE Classes  ?
  • 35 - Advertising and business services
  • 41 - Education, entertainment, sporting and cultural services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Advertising; Business management; Business administration; Office functions. Education; Providing of training; Entertainment; Sporting and cultural activities. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software.

25.

STRUCTURED GAS-CONTAINING SURFACES

      
Application Number EP2019059294
Publication Number 2019/201744
Status In Force
Filing Date 2019-04-11
Publication Date 2019-10-24
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to structured gas-containing surfaces for improving the friction-reducing properties of gas layers held under a liquid and for the simultaneous suppression of turbulences. The present invention further relates to a device comprising said structured gas-containing surface and to the use of said structured gas-containing surface.

IPC Classes  ?

  • F15D 1/00 - Influencing the flow of fluids
  • B08B 17/06 - Preventing deposition of fouling or of dust by giving articles subject to fouling a special shape for arrangement
  • B63B 1/36 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using mechanical means
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B63B 59/04 - Preventing hull fouling

26.

STRUCTURED GAS-CONTAINING SURFACES

      
Document Number 03097076
Status Pending
Filing Date 2019-04-11
Open to Public Date 2019-10-24
Owner BADEN-WURTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to structured gas-containing surfaces for improving the friction-reducing properties of gas layers held under a liquid and for the simultaneous suppression of turbulences. The present invention further relates to a device comprising said structured gas-containing surface and to the use of said structured gas-containing surface.

IPC Classes  ?

  • B08B 17/06 - Preventing deposition of fouling or of dust by giving articles subject to fouling a special shape for arrangement
  • B63B 1/36 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using mechanical means
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B63B 59/04 - Preventing hull fouling
  • F15D 1/00 - Influencing the flow of fluids

27.

Method of fabricating a multi-aperture system for foveated imaging and corresponding multi-aperture system

      
Application Number 16342786
Grant Number 11095813
Status In Force
Filing Date 2016-10-18
First Publication Date 2019-08-22
Grant Date 2021-08-17
Owner Baden-Wuerttemberg Stiftung gGmbH (Germany)
Inventor
  • Thiele, Simon
  • Giessen, Harald
  • Gissibl, Timo
  • Arzenbacher, Kathrin
  • Herkommer, Alois M.

Abstract

forming, by means of a 3D-printing technique, at least two imaging elements directly on the image sensor such that the imaging elements have a common focal plane located on the image sensor and each imaging element has a different focal length and field of view.

IPC Classes  ?

  • H04N 5/232 - Devices for controlling television cameras, e.g. remote control
  • B33Y 80/00 - Products made by additive manufacturing
  • G03F 7/00 - Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printed surfacesMaterials therefor, e.g. comprising photoresistsApparatus specially adapted therefor
  • H04N 5/225 - Television cameras
  • G02B 27/10 - Beam splitting or combining systems
  • B33Y 10/00 - Processes of additive manufacturing
  • B29D 11/00 - Producing optical elements, e.g. lenses or prisms

28.

expedition d DIGITALE TECHNOLOGIEN ANWENDUNGEN BERUFE

      
Application Number 018017270
Status Registered
Filing Date 2019-01-31
Registration Date 2019-06-14
Owner Baden-Württemberg Stiftung gGmbH (Germany)
NICE Classes  ?
  • 35 - Advertising and business services
  • 41 - Education, entertainment, sporting and cultural services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Advertising; Business management; Business administration; Office functions. Education; Providing of training; Entertainment; Sporting activities; Cultural activities; Vocational guidance [education or training advice]; Vocational skills training (Provision of -); Arranging of workshops for vocational guidance; Arranging professional workshop and training courses; Organisation of conferences relating to vocational training; Consultancy relating to vocational skills training; Computerised training in career counselling; Providing on-line information and news in the field of employment training; Providing of information relating to training and vocational guidance (education or training advice); Arranging and conducting of exhibitions for educational purposes. Scientific and technological services and research and design relating thereto; Industrial analysis services; Industrial research; Design and development of computer hardware and computer software; Providing of information relating to digitisation; Providing of information relating to digitisation at work.

29.

METHOD OF FABRICATING AN IMAGING SYSTEM AND CORRESPONDING IMAGING SYSTEM

      
Application Number EP2017000869
Publication Number 2019/015735
Status In Force
Filing Date 2017-07-18
Publication Date 2019-01-24
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Thiele, Simon
  • Giessen, Harald
  • Pruss, Christof
  • Herkommer, Alois

Abstract

The present invention relates to a method of fabricating an imaging system as well as to a corresponding imaging system. The method comprises the steps of: - providing a substrate; - forming, by means of a 3D-printing technique, a 3D-structure (100) on the substrate, wherein the forming of the 3D-structure (100) comprises forming a stack of at least two diffractive optical elements (10) in a single printing step.

IPC Classes  ?

30.

CATIONIZED, PROTEIN-BASED, MACROPOROUS SCAFFOLD STRUCTURES AND USE THEREOF FOR CELL CULTURE

      
Application Number EP2018068272
Publication Number 2019/008106
Status In Force
Filing Date 2018-07-05
Publication Date 2019-01-10
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Lee-Thedieck, Cornelia
  • Raic, Annamarija
  • Rosenau, Frank
  • Bodenberger, Nicholas

Abstract

The present invention relates to a three-dimensional macroporous scaffold structure comprising cross-linked cationized bovine serum albumin. The invention also relates to a production method for the three-dimensional macroporous scaffold structure, to a method for culturing cells in the three-dimensional macroporous scaffold structure and to a kit comprising said three-dimensional macroporous scaffold structure.

IPC Classes  ?

  • A61L 27/22 - Polypeptides or derivatives thereof
  • A61L 27/38 - Animal cells
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

31.

A CONJUGATE COMPLEX FACILITATING THE TRANSPORT OF A CARGO THROUGH A MEDIUM

      
Application Number EP2018066893
Publication Number 2019/002177
Status In Force
Filing Date 2018-06-25
Publication Date 2019-01-03
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Rothenstein, Dirk
  • Bill, Joachim
  • Fischer, Peer

Abstract

The present invention relates to conjugate complexes, comprising at least one biological entity, at least one cargo moiety, and at least one effector moiety that is capable of converting, degrading, and/or modifying a given medium, wherein the at least one cargo moiety and the at least one effector moiety are directly or indirectly coupled to the biological entity. The present invention further relates to uses thereof and methods for facilitating the transport of a cargo moiety through a given medium.

IPC Classes  ?

  • A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
  • C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof

32.

Device for switchably influencing electromagnetic radiation, and method for obtaining such a device

      
Application Number 15992264
Grant Number 10593873
Status In Force
Filing Date 2018-05-30
First Publication Date 2018-12-06
Grant Date 2020-03-17
Owner BADEN-WURTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Giessen, Harald
  • Yin, Xinghui

Abstract

A device for switchably influencing electromagnetic radiation includes a phase change material and an optically responsive structure. The phase change material is switchable between at least a first state and a second state. The first state and the second state have different electrical and/or magnetic properties. The optically responsive structure is in contact with the phase change material and has at least a first nanostructure and a second nanostructure. The first nanostructure is being different from the second nanostructure. The first nanostructure is optically responsive at a predetermined electromagnetic wavelength when the phase change material is in its first state, and non-responsive at the predetermined wavelength when the phase change material is in its second state. The second nanostructure is optically responsive at the predetermined electromagnetic wavelength when the phase change material is in its second state, and non-responsive at the predetermined wavelength when the phase change material is in its first state.

IPC Classes  ?

  • H01L 45/00 - Solid state devices specially adapted for rectifying, amplifying, oscillating, or switching without a potential-jump barrier or surface barrier, e.g. dielectric triodes; Ovshinsky-effect devices; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof
  • G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
  • G02F 1/29 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the position or the direction of light beams, i.e. deflection

33.

Method and device for producing microstructures on optical fibers

      
Application Number 15765914
Grant Number 10870243
Status In Force
Filing Date 2016-10-07
First Publication Date 2018-10-04
Grant Date 2020-12-22
Owner
  • BADEN-WÜRTTEMBERG STIFTUNG gGmbH (Germany)
  • Nanoscribe GmbH (Germany)
Inventor
  • Gießen, Harald
  • Thiel, Michael
  • Gissibl, Timo

Abstract

a) of the optical fiber (1) with photoresist (2); —orienting (S30) the optical fiber (1) and a writing beam of a 3D printer with respect to one another; —forming (S40) the at least one microstructure (5) by exposing the photoresist (2) to light with the aid of the 3D printer.

IPC Classes  ?

  • B29D 11/00 - Producing optical elements, e.g. lenses or prisms
  • G02B 6/26 - Optical coupling means
  • B33Y 10/00 - Processes of additive manufacturing
  • B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
  • B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
  • B29C 64/135 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask the energy source being concentrated, e.g. scanning lasers or focused light sources

34.

METHOD FOR TREATING THE SURFACE OF A HARD METAL BODY AND FOR COATING THE TREATED HARD METAL BODY WITH A DIAMOND LAYER

      
Application Number EP2018050706
Publication Number 2018/130628
Status In Force
Filing Date 2018-01-12
Publication Date 2018-07-19
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Mee, Manuel

Abstract

The invention relates to a method for treating the surface (110) of a hard metal body (112). The method has the following steps: a) providing a hard metal body (112), said hard metal body (112) comprising at least one carbide phase of a metal of the 4th to 6th subgroup of the periodic table of elements and at least one binding metal; b) forming at least one low-carbon ternary phase comprising the metal of the carbide phase, the binding metal, and carbon in a surface zone (114) of the hard metal body (112); c) supplying carbon into the surface zone (114) over an outer surface (122), wherein the binding metal in the surface zone (114) is at least partly converted into a gas phase, recrystallized grains of the carbide phase are formed within the surface zone (114), and the binding metal transitions into a wetting agent (124) of the outer surface (122) of the surface zone (114) and is present in a surface zone (114) region (128) remote from the surface such that the binding metal is bound in the low-carbon ternary phase in intermediate spaces of the recrystallized grains; and d) converting the low-carbon ternary phase in intermediate spaces of the recrystallized grains in a surface zone (114) region (128) remote from the surface into a phase which stabilizes the binding metal; whereby a treated surface (138) of the hard metal body (112) is obtained. The invention additionally relates to a method for coating a hard metal body (130) treated in such a manner with at least one diamond layer (132).

IPC Classes  ?

  • C23C 8/02 - Pretreatment of the material to be coated
  • C23C 8/12 - Oxidising using elemental oxygen or ozone
  • C23C 8/20 - Carburising
  • C23C 8/80 - After-treatment
  • C23C 16/02 - Pretreatment of the material to be coated
  • C23C 16/27 - Diamond only
  • C23C 28/00 - Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of main groups , or by combinations of methods provided for in subclasses and

35.

MEASUREMENT SYSTEM AND METHOD FOR COMBINED CAPTURE OF THE SURFACE TOPOGRAPHY AND HYPERSPECTRAL IMAGING

      
Application Number EP2018050891
Publication Number 2018/130693
Status In Force
Filing Date 2018-01-15
Publication Date 2018-07-19
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Stock, Karl
  • Mader, Raphael

Abstract

The present invention relates, in particular, to a method and an apparatus for capturing topographic and spatially resolved, spectral properties of a surface to be examined. Here, the method comprises: producing an illumination pattern of a first measurement light with a multiplicity of wavelengths; imaging the illumination pattern of the first measurement light onto the surface to be examined by means of a chromatic objective in such a way that, by way of the chromatic objective, the illumination pattern is imaged in focus at different distances for different wavelengths of the multiplicity of wavelengths of the first measurement light; imaging the first measurement light radiated by the surface to be examined by means of the chromatic objective onto a confocal mask, which has a transmission pattern corresponding to the illumination pattern; spectrally splitting the first measurement light transmitted through the confocal mask; capturing a 2-dimensional intensity distribution of the spectrally split first measurement light with spatial resolution by means of the detector; ascertaining the topographic properties of the surface to be examined on the basis of the intensity distribution of the first measurement light captured by means of the detector; homogeneously illuminating the surface to be examined by means of a second measurement light with a multiplicity of wavelengths; imaging the second measurement light radiated by the surface to be examined by means of the chromatic objective onto the confocal mask; spectrally splitting the second measurement light transmitted through the confocal mask; capturing a 2-dimensional intensity distribution of the spectrally split second measurement light with spatial resolution by means of the detector; and ascertaining the spatially resolved, spectral properties of the surface to be examined on the basis of the intensity distribution of the second measurement light captured by means of the detector.

IPC Classes  ?

  • G01B 11/24 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
  • A61C 9/00 - Impression methods specially adapted for dental prostheticsImpression cups therefor

36.

Microscope for molecular spectroscopic analysis

      
Application Number 15572111
Grant Number 10317655
Status In Force
Filing Date 2016-05-06
First Publication Date 2018-06-07
Grant Date 2019-06-11
Owner Baden-Wuerttemberg Stiftung gGmbH (Germany)
Inventor Kroeger-Lui, Niels

Abstract

The invention relates to a microscope for the molecular spectroscopic analysis of a sample (2), having a beam path having at least one quantum cascade laser (QCL) (3) which emits an infrared (IR) radiation, a phase modulator (5) which is arranged between the QCL (3) and the sample (2), at least one optical element (6) which is arranged between the phase modulator (5) and the sample (2) and a sensor (4) which detects an IR radiation which is transmitted and/or reflected by the sample (2). The invention relates further to a method for the molecular spectroscopic analysis of a sample (2) comprising the steps of irradiating the sample (2) with an infrared (IR) radiation by means of a quantum cascade laser (QCL) (3), wherein the IR radiation is directed onto the sample (2) via a phase modulator (5) and at least one optical element (6), and detecting the IR radiation which is reflected and/or transmitted by the sample (2).

IPC Classes  ?

  • G01J 3/40 - Measuring the intensity of spectral lines by determining density of a photograph of the spectrumSpectrography
  • G02B 21/00 - Microscopes
  • G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
  • G01J 3/42 - Absorption spectrometryDouble-beam spectrometryFlicker spectrometryReflection spectrometry
  • G02B 21/06 - Means for illuminating specimen
  • G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
  • G01J 3/28 - Investigating the spectrum
  • G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light

37.

Optical device and use of the device

      
Application Number 15578886
Grant Number 10359547
Status In Force
Filing Date 2016-06-03
First Publication Date 2018-06-07
Grant Date 2019-07-23
Owner BADEN-WURTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to an optical device (100) and a use of the optical device (100). The optical device (100) comprises: —a source electrode (2); —a drain electrode (4); —a gap area (6) between the source electrode (2) and the drain electrode (4); —a cluster (8) being positioned in the gap area (6) for connecting and disconnecting the source electrode (2) and the drain electrode (4) and for changing optical and/or plasmonic properties of the gap area (6); and an optical coupling element (10) for bringing light into and out of the gap area (6).

IPC Classes  ?

  • G02F 1/03 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on ceramics or electro-optical crystals, e.g. exhibiting Pockels or Kerr effect
  • G02B 5/00 - Optical elements other than lenses
  • H01L 51/05 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for rectifying, amplifying, oscillating or switching and having at least one potential-jump barrier or surface barrier; Capacitors or resistors with at least one potential-jump barrier or surface barrier
  • B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
  • G02B 6/122 - Basic optical elements, e.g. light-guiding paths

38.

METHOD OF FABRICATING A MULTI-APERTURE SYSTEM FOR FOVEATED IMAGING AND CORRESPONDING MULTI-APERTURE SYSTEM

      
Application Number EP2016001721
Publication Number 2018/072806
Status In Force
Filing Date 2016-10-18
Publication Date 2018-04-26
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Thiele, Simon
  • Giessen, Harald
  • Gissibl, Timo
  • Arzenbacher, Kathrin
  • Herkommer, Alois M.

Abstract

The present invention relates to a method of fabricating a multi-aperture system (100) for foveated imaging as well as to a corresponding multi-aperture system (100). The method comprises the steps of: - providing an image sensor (1); and - forming, by means of a 3D-printing technique, at least two imaging elements (11 -14) directly on the image sensor (1 ) such that the imaging elements (11 -14) have a common focal plane located on the image sensor (1) and each imaging element (11 - 14) has a different focal length and/or field of view.

IPC Classes  ?

39.

LECTIN FOR REVERSIBLE CELL IMMOBILISATION

      
Application Number EP2017001071
Publication Number 2018/046129
Status In Force
Filing Date 2017-09-11
Publication Date 2018-03-15
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Rosenau, Frank
  • Bodenberger, Nicholas

Abstract

The invention relates to methods for producing hydrogels for reversibly immobilising glycoproteins and/or cells on the hydrogel, involving lectins being coupled to the hydrogel, corresponding lectin-coupled hydrogels, the use thereof in 3D cell culture, and corresponding methods for reversibly immobilising glycoproteins and/or cells on such hydrogels.

IPC Classes  ?

  • C12N 11/04 - Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
  • C12N 11/06 - Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
  • C12N 11/08 - Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
  • C07K 17/04 - Peptides being immobilised on, or in, an organic carrier entrapped within the carrier, e.g. gel, hollow fibre
  • C07K 17/06 - Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
  • C07K 17/08 - Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

40.

METHOD AND DEVICE FOR SPATIALLY CONTROLLED PARALLEL TRANSFECTION - FLOATING WELLS

      
Application Number EP2017000100
Publication Number 2017/129367
Status In Force
Filing Date 2017-01-27
Publication Date 2017-08-03
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Erfle, Holger
  • Lisauskas, Tautvydas
  • Starkuviene, Vytaute

Abstract

The present invention relates to floating wells comprised in a cell carrier, wherein the cell carrier comprises a solid carrier, and the floating wells are located on the surface of the solid carrier. Further, the present invention relates to a cell carrier comprising a solid carrier comprising on a surface a plurality of spots having a spot size X, and cells on the surface of the solid carrier, a manufacturing method of a cell carrier and the use of the cell carrier for solid phase transfection and for transduction with viruses.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

41.

Gas-containing surface cover, arrangement, and use

      
Application Number 15422062
Grant Number 10625833
Status In Force
Filing Date 2017-02-01
First Publication Date 2017-07-20
Grant Date 2020-04-21
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.

IPC Classes  ?

  • B63B 59/04 - Preventing hull fouling
  • F16L 58/02 - Protection of pipes or pipe fittings against corrosion or incrustation by means of internal or external coatings
  • B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B32B 3/30 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids characterised by a layer formed with recesses or projections, e.g. grooved, ribbed
  • F15D 1/00 - Influencing the flow of fluids
  • F16L 57/06 - Protection of pipes or objects of similar shape against external or internal damage or wear against wear
  • B05D 5/02 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a matt or rough surface

42.

Method and device for producing an optical element having at least one functional region, as well as use of the device

      
Application Number 15336500
Grant Number 10654232
Status In Force
Filing Date 2016-10-27
First Publication Date 2017-05-04
Grant Date 2020-05-19
Owner BADEN-WUERTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Thiele, Simon
  • Giessen, Harald
  • Gissibl, Timo
  • Herkommer, Alois M.

Abstract

filling the at least one microfluidic cavity (4) with the functional substance (6) for forming the at least one functional region. In addition, the invention relates to a device for manufacturing an optical element (100) as well as a use of the device.

IPC Classes  ?

  • B29D 11/00 - Producing optical elements, e.g. lenses or prisms
  • G02B 5/00 - Optical elements other than lenses
  • G02B 13/00 - Optical objectives specially designed for the purposes specified below
  • G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
  • G02B 3/12 - Fluid-filled or evacuated lenses
  • G02B 26/00 - Optical devices or arrangements for the control of light using movable or deformable optical elements
  • B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
  • B33Y 80/00 - Products made by additive manufacturing
  • B33Y 40/00 - Auxiliary operations or equipment, e.g. for material handling
  • B33Y 10/00 - Processes of additive manufacturing

43.

METHOD AND DEVICE FOR PRODUCING MICROSTRUCTURES ON OPTICAL FIBRES

      
Application Number EP2016001686
Publication Number 2017/059960
Status In Force
Filing Date 2016-10-07
Publication Date 2017-04-13
Owner
  • BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
  • NANOSCRIBE GMBH (Germany)
Inventor
  • Gießen, Harald
  • Gissibl, Timo
  • Thiel, Michael

Abstract

The invention relates to a method and a device for producing at least one microstructure (5) on an axial end (1a) of an optical fibre (1). The method comprises the following steps: - providing (S10) the optical fibre (1); - wetting (S20) the axial end (1a) of the optical fibre (1) with photoresist (2); - orienting (S30) the optical fibre (1) and a writing beam of a 3D printer with respect to one another; - forming (S40) the at least one microstructure (5) by exposing the photoresist (2) to light with the aid of the 3D printer.

IPC Classes  ?

44.

METHOD FOR AN OPTICAL DISTANCE MEASUREMENT, SENSOR ASSEMBLY, AND USE THEREOF

      
Application Number EP2015001986
Publication Number 2017/059879
Status In Force
Filing Date 2015-10-08
Publication Date 2017-04-13
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Wölfelschneider, Harald

Abstract

The invention relates to a method and a sensor assembly (1) for obtaining distance information with respect to a surface (2) to be measured. The sensor assembly (1) is operated according to the confocal principle and has a lighting device (3) with at least one first light source (4a), and the light of the first light source is coupled into a lighting beam path, along which the light is first guided at least partly in the direction of the pertinent surface (2) and is focused into different focal points (18a) in order to then be detected in the form of received signals by at least one detector (10a) of a detection device (20) after being reflected on the surface to be measured. The aim of the invention is to provide a method and a sensor assembly (1) which ensure a faster supply of robust depth information at a sufficient depth resolution. This is achieved by coupling transmission signals of a plurality of narrow-band light sources (4a, 4b) into the lighting beam path in the form of light, each transmission signal being focused onto different focal points (18a, 18b), and differentiating between signals originating from different light sources (4a, 4b) using at least one unique modulation pattern. By using filter elements, a high resistance to stray light can be achieved.

IPC Classes  ?

  • G01B 11/02 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness
  • G02B 21/24 - Base structure

45.

Device with switchable, chiral optical properties, means for polarization modulation, and related method

      
Application Number 15169865
Grant Number 10241353
Status In Force
Filing Date 2016-06-01
First Publication Date 2017-03-02
Grant Date 2019-03-26
Owner BADEN-WURTTEMBERG STIFFUNG GMBH (Germany)
Inventor
  • Giessen, Harald
  • Yin, Xinghui

Abstract

A device with switchable, chiral optical characteristics, has a first chiral arrangement with a first arrangement layer with at least one first nanostructure and a second arrangement layer with at least one second nanostructure. The first nanostructure and the second nanostructure are arranged relative to one another such that the chiral arrangement is chiral. A switching material with switchable dielectric characteristics is arranged between the first arrangement layer and the second arrangement layer.

IPC Classes  ?

  • G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
  • G02B 5/00 - Optical elements other than lenses
  • G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
  • G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising

46.

OPTICAL DEVICE AND USE OF THE DEVICE

      
Application Number EP2016000925
Publication Number 2016/192859
Status In Force
Filing Date 2016-06-03
Publication Date 2016-12-08
Owner
  • BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
  • KARLSRUHER INSTITUT FÜR TECHNOLOGIE (Germany)
Inventor Schimmel, Thomas

Abstract

The present invention relates to an optical device (100) and a use of the optical device (100). The optical device (100) comprises: - a source electrode (2); - a drain electrode (4); - a gap area (6) between the source electrode (2) and the drain electrode (4); - a cluster (8) being positioned in the gap area (6) for connecting and disconnecting the source electrode (2) and the drain electrode (4) and for changing optical and/or plasmonic properties of the gap area (6); and an optical coupling element (10) for bringing light into and out of the gap area (6).

IPC Classes  ?

  • G02B 5/00 - Optical elements other than lenses
  • H01L 51/05 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for rectifying, amplifying, oscillating or switching and having at least one potential-jump barrier or surface barrier; Capacitors or resistors with at least one potential-jump barrier or surface barrier

47.

MICROSCOPE FOR MOLECULAR SPECTROSCOPIC ANALYSIS

      
Application Number EP2016060230
Publication Number 2016/177897
Status In Force
Filing Date 2016-05-06
Publication Date 2016-11-10
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Kröger-Lui, Niels

Abstract

The invention relates to a microscope (1) for the molecular spectroscopic analysis of a sample (2), comprising a beam path having at least one quantum cascade laser (QCL) (3) which emits an infrared (IR) radiation, a phase modulator (5) which is arranged between the QCL (3) and the sample (2), at least one optical element (6) which is arranged between the phase modulator (5) and the sample (2), and a sensor (4) which detects IR radiation transmitted and/or reflected by the sample (2). The invention further relates to a method for the molecular spectroscopic analysis of a sample (2), having the steps of irradiating the sample (2) with infrared (IR) radiation by means of a quantum cascade laser (QCL) (3), said IR radiation being deflected onto the sample via a phase modulator (5) and at least one optical element (6), and detecting the IR radiation reflected and/or transmitted by the sample (2).

IPC Classes  ?

  • G02B 21/00 - Microscopes
  • G01J 3/02 - SpectrometrySpectrophotometryMonochromatorsMeasuring colours Details
  • G01J 3/42 - Absorption spectrometryDouble-beam spectrometryFlicker spectrometryReflection spectrometry
  • G02B 21/06 - Means for illuminating specimen
  • G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes

48.

Optical system and method

      
Application Number 15061662
Grant Number 09735536
Status In Force
Filing Date 2016-03-04
First Publication Date 2016-09-15
Grant Date 2017-08-15
Owner Baden-Wuerttemberg Stiftung gGmbH (Germany)
Inventor
  • Giessen, Harald
  • Steinle, Tobias
  • Steinmann, Andy

Abstract

Optical system and method for the provision of at least one high-frequency modulated light pulse having a pump light source for the provision of high-frequency pump light pulses; an optical resonator having a coupling element for coupling the pump light pulses into the resonator and a decoupling element for decoupling the at least one high-frequency modulated light pulse from the resonator and an optically non-linear frequency conversion medium arranged in the resonator for transforming the pump light pulses in each case into two conversion light pulses and one residual pump light pulse. The resonator comprises a feedback arm for at least one of the two conversion light pulses and/or the residual pump light pulse, in which an optically non-linear feedback medium is arranged for the optical modulation of the at least one conversion light pulse and/or the residual pump light pulse.

IPC Classes  ?

  • H01S 3/108 - Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity using non-linear optical devices, e.g. exhibiting Brillouin or Raman scattering
  • H01S 3/094 - Processes or apparatus for excitation, e.g. pumping using optical pumping by coherent light
  • G02F 1/139 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells characterised by the electro-optical or magneto-optical effect, e.g. field-induced phase transition, orientation effect, guest-host interaction or dynamic scattering based on orientation effects in which the liquid crystal remains transparent

49.

SYSTEM AND METHOD FOR DISTANCE MEASUREMENT

      
Application Number EP2015000652
Publication Number 2015/149920
Status In Force
Filing Date 2015-03-26
Publication Date 2015-10-08
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Koos, Christian
  • Weimann, Claudius
  • Fratz, Markus
  • Wölfelschneider, Harald

Abstract

The present invention relates to a system and a method for distance measurement. The system for distance measurement comprises - a multiple-wavelength holography module (100) for detecting a holography measurement data set for at least one measurement point on the basis of at least one synthetic wavelength, the multiple-wavelength holography module (100) having: - at least two holography light sources (110, 112, 114, 116) for generating at least two coherent holography light beams having different wavelengths, - at least one beam splitter (124, 160) for splitting each holography light beam into an object light beam (155) and a reference light beam (135), and - at least one diffraction element (134, 138) for the dispersive diffraction of the reference light beams (135).

IPC Classes  ?

50.

Gas-containing surface cover, arrangement, and use

      
Application Number 14382482
Grant Number 09630373
Status In Force
Filing Date 2013-02-22
First Publication Date 2015-10-01
Grant Date 2017-04-25
Owner Baden-Württemberg Stiftung gGmbH (Germany)
Inventor Schimmel, Thomas

Abstract

An aspect of the invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.

IPC Classes  ?

  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • F16L 58/02 - Protection of pipes or pipe fittings against corrosion or incrustation by means of internal or external coatings
  • B32B 3/30 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids characterised by a layer formed with recesses or projections, e.g. grooved, ribbed
  • B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
  • F16L 57/06 - Protection of pipes or objects of similar shape against external or internal damage or wear against wear
  • B05D 5/02 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a matt or rough surface

51.

FILTRATION-ACTIVE FUEL CELL

      
Application Number EP2014002059
Publication Number 2015/014474
Status In Force
Filing Date 2014-07-28
Publication Date 2015-02-05
Owner
  • BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
  • ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (Germany)
Inventor
  • Danzer, Joana
  • Kerzenmacher, Sven

Abstract

The invention relates to a filtration-active fuel cell and to the use thereof in the treatment and processing of fluids, in particular liquids, wherein the filtration-active layer of a membrane filter is simultaneously used as an anode of a fuel cell.

IPC Classes  ?

  • H01M 8/16 - Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
  • H01M 4/90 - Selection of catalytic material
  • C02F 3/00 - Biological treatment of water, waste water, or sewage

52.

SOLID PHASE TRANSFECTION OF PROTEINS AND NUCLEIC ACIDS

      
Application Number EP2014001924
Publication Number 2015/007383
Status In Force
Filing Date 2014-07-14
Publication Date 2015-01-22
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Erfle, Holger
  • Starkuviene-Erfle, Vytaute
  • Bulkescher, Ruben

Abstract

The present invention relates to a method for solid phase transfection of at least one protein and at least one nucleic acid molecule into at least one cell comprising the step of providing a solid carrier containing at least one spot comprising a transfection reagent, at least one protein and the at least one nucleic acid molecule as well as to a solid carrier containing at least one spot comprising a transfection reagent, at least one protein and the at least one nucleic acid molecule.

IPC Classes  ?

  • C12N 15/87 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

53.

MODIFIED EXPRESSION OF PROLYL-4-HYDROXYLASE IN PHYSCOITRELLA PATENS

      
Application Number EP2014059132
Publication Number 2014/180793
Status In Force
Filing Date 2014-05-05
Publication Date 2014-11-13
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Reski, Ralf
  • Parsons, Juliana
  • Altmann, Friedrich
  • Graf, Manuela
  • Decker, Eva
  • Stadlmann, Johannes

Abstract

The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.

IPC Classes  ?

  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
  • C12N 9/06 - Oxidoreductases (1.), e.g. luciferase acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)

54.

A METHOD FOR AUTOMATED PLATFORM AND/OR REFERENCE OBJECT INDEPENDENT ACQUISITION OF POSITIONAL INFORMATION AND LOCALIZATION OF OBJECTS OF INTEREST IN A MICROSCOPE

      
Application Number EP2014001111
Publication Number 2014/173547
Status In Force
Filing Date 2014-04-25
Publication Date 2014-10-30
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Erfle, Holger
  • Gunkel, Manuel
  • Reymann, Jürgen

Abstract

The present invention relates to microscopic methods and respective apparatuses and/or systems for automated platform and/or reference object independent multidimensional localization of objects of interest as well as microscopic methods and respective apparatuses for automated platform and/or reference object independent acquisition of positional data of objects of interest. According to an aspect, there is provided a method for obtaining positional data of at least one object of interest within a probe by using a microscope comprising determining the positions of at least two reference markings in at least one image obtained by the microscope; determining a reference coordinate system associated with said reference markings based on the determined positions of the reference markings and data concerning the position of a probe positioning device of the microscope and determining positional information of one or more objects of interest in the reference coordinate system. The positional information may used by another microscope to re-locate objects of interest. According to another aspect, which is particularly applicable for highly accurate, fine adjustment of positional information and/or object location, a method for obtaining positional information and/or object location is proposed, which relies on detecting specific target objects and/or regions and/or patterns within the image of the probe and using the detected target objects and/or regions and/or patterns for correcting positional data of objects of interest (hits). This method may be combined with any of the above described methods according to aspects of the invention.

IPC Classes  ?

  • G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes

55.

SYSTEM FOR THE CAGING AND CONTROLLED RELEASE OF PROTEINS

      
Application Number EP2013000393
Publication Number 2014/121806
Status In Force
Filing Date 2013-02-08
Publication Date 2014-08-14
Owner
  • BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
  • ETH ZÜRICH (Switzerland)
Inventor
  • Weber, Wilfried
  • Hörner, Maximilian
  • Karlsson, Maria

Abstract

The present invention relates to a system for the caging and controlled release of at least one protein of interest, said system comprising e.g. a phytochrome B that is coupled to a capture reagent and e.g. a phytochrome interacting factor to which the at least one protein of interest is coupled. The present invention further relates to a method for the caging and controlled release of at least one protein of interest, said method using said system, as well as a kit comprising e.g. a phytochrome B that is coupled to a capture reagent and e.g. a phytochrome interacting factor that is coupled to a binding domain. Moreover, the present invention relates to the use of said system for the controlled release of at least one protein of interest. The system and method of the present invention can be used for the purification of the protein of interest.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

56.

SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS

      
Application Number EP2013069014
Publication Number 2014/041125
Status In Force
Filing Date 2013-09-13
Publication Date 2014-03-20
Owner BADEN-WÜRTTEMBERG STIFTUNG GMBH (Germany)
Inventor
  • Günes, Cagatay
  • Hoffman, Elena Marita
  • Rudolph, Karl Lenhard

Abstract

The present invention relates to novel inhibitors of p21. These inhibitors are useful as therapeutic agents for promoting cell regeneration and in the treatment of cancer. Improvement of cell regeneration is particularly desirable in patients of old age or in patients suffering from chronic diseases, acute or chronic injuries.

IPC Classes  ?

  • C07D 219/14 - Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
  • C07D 471/04 - Ortho-condensed systems
  • C07D 471/06 - Peri-condensed systems
  • C07D 487/04 - Ortho-condensed systems
  • C07D 498/04 - Ortho-condensed systems
  • C07D 311/58 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulfur atoms in position 2 or 4
  • C07D 221/14 - Aza-phenalenes, e.g. 1,8-naphthalimide
  • C07D 249/14 - Nitrogen atoms
  • C07C 233/65 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
  • A61K 31/404 - Indoles, e.g. pindolol
  • A61K 31/4985 - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
  • A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
  • A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
  • A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
  • A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
  • A61K 31/4196 - 1,2,4-Triazoles

57.

METHOD FOR OPERATING A LASER WELDING DEVICE AND DEVICE

      
Application Number EP2012002795
Publication Number 2014/005603
Status In Force
Filing Date 2012-07-03
Publication Date 2014-01-09
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Blug, Andreas
  • Abt, Felix
  • Nicolosi, Leonardo
  • Heider, Andreas

Abstract

The invention relates to a method for operating a laser welding device for welding workpieces by means of a laser beam, in which method a change in an optically detectable feature that accompanies a change in at least one first controlled variable of the welding process is detected by means of at least one detection means, and at least a first manipulated variable for processing by at least one control device is produced by at least one data processing unit on the basis of the change in the feature. The invention also relates to a device for carrying out such a method. In order to provide a laser welding device and a method for operating a laser welding device for welding workpieces that adjust themselves to the production conditions and at the same time minimize the occurrence of weld defects, it is proposed that, when the change in a feature that can be optically detected occurs, first of all the first manipulated variable is selected from a plurality of possible first manipulated variables and changed according to process requirements and that, in order to keep a second controlled variable of the welding process substantially constant, at least one further manipulated variable that is different from the selected first manipulated variable is changed for correspondingly controlling the second controlled variable.

IPC Classes  ?

  • B23K 26/03 - Observing, e.g. monitoring, the workpiece
  • B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing
  • B23K 26/073 - Shaping the laser spot

58.

A LIGHT REGULATED TRANSGENE EXPRESSION SYSTEM

      
Application Number EP2013001650
Publication Number 2013/185892
Status In Force
Filing Date 2013-06-05
Publication Date 2013-12-19
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Weber, Wilfried
  • Zubriggen, Matias
  • Müller, Konrad
  • Kämpf, Michael
  • Nagy, Ference

Abstract

The present invention relates to a system for the light-regulated expression of a transgene in a mammalian cell which can repeatedly and reversibly be activated and inactivated by illumination with light, based on the use of a split transcription factor that is present in the nucleus. The present invention further relates to an isolated nucleic acid molecule encoding said split transcription factor, a vector comprising said nucleic acid, a host cell comprising said system, isolated nucleic acid or vector, and a method for the light-regulated expression of a transgene in a cell, said method using the system of the present invention. Furthermore, the present invention relates to a kit for performing said method, and uses of the above.

IPC Classes  ?

  • C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

59.

PRODUCTION OF MICRO- OR SUPERMICROFIBRES BASED ON CELLULOSE

      
Application Number EP2013000676
Publication Number 2013/139441
Status In Force
Filing Date 2013-03-07
Publication Date 2013-09-26
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Hermanutz, Frank
  • Ingildeev, Denis
  • Effenberger, Franz

Abstract

The present invention relates to an environmentally friendly process for producing continuous micro- or supermicrofibres based on cellulose, which can be used for the production of filaments, textile fabrics, paper, filters, absorption materials, and hygiene and cosmetic articles.

IPC Classes  ?

  • D01D 4/02 - Spinnerettes
  • D01F 2/02 - Monocomponent artificial filaments or the like of cellulose or cellulose derivativesManufacture thereof from solutions of cellulose in acids, bases, or salts
  • D01F 2/28 - Monocomponent artificial filaments or the like of cellulose or cellulose derivativesManufacture thereof from cellulose derivatives from organic cellulose esters or ethers, e.g. cellulose acetate

60.

USE OF A GAS-RETAINING LAYER WHICH IS ARRANGED ON A BODY THAT IS IMMERSIBLE IN A LIQUID OR WETTABLE BY THE LIQUID

      
Document Number 02866082
Status In Force
Filing Date 2013-02-22
Open to Public Date 2013-09-12
Grant Date 2021-06-22
Owner BADEN-WURTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Schimmel, Thomas

Abstract

AbstractA gas-retaining surface covering for a body that can be placed in contact with a liquid, and to a corresponding arrangement and to a use. In accordance with one aspect, there is provided a use of a gas-retaining layer which is arranged on a body that is immersible in a liquid or wettable by a liquid and which is in contact by way of a liquid-facing side with a liquid when the body is immersed in/wetted by the liquid. The gas-retaining layer has on the liquid-facing side recesses and/or protruding elements whose surfaces are hydrophobic at least regionally. A gas layer is retained in the immersed/wetted region of the gas-retaining layer that separates the liquid and the immersed/wetted region of the body from one another at least regionally. The gas-retaining layer may be divided into a multiplicity of sub-regions by fluid-impermeable partitions or the protruding elements may have a central surface region which is hydrophilic and which is surrounded by a hydrophobic surface region of the protruding elements. The gas-retaining layer allows for a gas volume to be retained on the body such that the body can be separated from the liquid surrounding the body by the gas-retaining layer or by the gas retained by the gas-retaining layer.CA 2866082 2019-04-30

IPC Classes  ?

  • B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B63B 59/00 - Hull protection specially adapted for vesselsCleaning devices specially adapted for vessels
  • C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water theretoThawing or antifreeze materials for application to surfaces

61.

USE OF A GAS-RETAINING LAYER WHICH IS ARRANGED ON A BODY THAT IS IMMERSIBLE IN A LIQUID OR WETTABLE BY THE LIQUID

      
Document Number 03114548
Status In Force
Filing Date 2013-02-22
Open to Public Date 2013-09-12
Grant Date 2023-05-09
Owner BADEN-WURTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Schimmel, Thomas

Abstract

A gas-retaining surface covering for a body that can be placed in contact with a liquid, and to a corresponding arrangement and to a use. In accordance with one aspect, there is provided a surface covering which comprises a gas-retaining layer which is designed and arranged so as to make contact by way of a liquid-facing side with the liquid. The gas-retaining layer has on the liquid-facing side protruding elements whose surfaces are hydrophobic, and wherein protruding elements have a central surface region which is hydrophilic and which is surrounded by a hydrophobic surface region of the protruding elements.

IPC Classes  ?

  • B05D 5/00 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
  • C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water theretoThawing or antifreeze materials for application to surfaces

62.

GAS-CONTAINING SURFACE COVER, ARRANGEMENT, AND USE

      
Application Number EP2013000523
Publication Number 2013/131618
Status In Force
Filing Date 2013-02-22
Publication Date 2013-09-12
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor Schimmel, Thomas

Abstract

An aspect of the invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.

IPC Classes  ?

  • B05D 5/00 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
  • B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
  • B63B 1/38 - Other means for varying the inherent hydrodynamic characteristics of hulls by reducing surface friction using air bubbles or air layers
  • B05D 5/02 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a matt or rough surface
  • B05D 5/04 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a surface receptive to ink or other liquid

63.

DIAGNOSIS AND/OR PROGNOSIS OF PARKINSON'S DISEASE DEMENTIA

      
Application Number EP2012062087
Publication Number 2012/175672
Status In Force
Filing Date 2012-06-22
Publication Date 2012-12-27
Owner BADEN-WÜRTTEMBERG STIFTUNG gGmbH (Germany)
Inventor
  • Otto, Markus
  • Lehnert, Stefan
  • Jesse, Sarah
  • Jahn, Olaf

Abstract

The present Invention provides a method for diagnosing and/or prognosing Parkinson's disease dementia (PDD) comprising the step of detecting O-glycosylation. in a protein comprising a Scr/Thr motive, in particular Serpin Al, and/or the level of sialic acid on a protein comprising a Ser/Thr motive, in particular Serpin Al. Further, the present invention relates to a molecule for detecting O-linked glycomoieties in a protein comprising a Ser/Thr motive, in particular Serpin Al, and/or glycosylated i so forms of a Ser/Thr motive comprising protein, in particular Serpin Al„ for use in the diagnosis and/or prognosis of Parkinson's disease dementia (PDD), Furthermore, the present invention relates to means for diagnosing and/or prognosing Parkinson's disease dementia (PDD) and a kit for diagnosing and/or prognosing Parkinson's disease dementia (PDD).

IPC Classes  ?

  • C07K 14/81 - Protease inhibitors
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

64.

DIAGNOSIS AND/OR PROGNOSIS OF A NEURODEGENERATIVE DISEASE

      
Application Number EP2012062089
Publication Number 2012/175674
Status In Force
Filing Date 2012-06-22
Publication Date 2012-12-27
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Otto, Markus
  • Lehnert, Stefan
  • Jesse, Sarah

Abstract

The present invention relates to a method for diagnosing and/or prognosing a neurodegenerative disease, particularly Parkinson's disease (PD) or Parkinson's disease dementia (PDD), which comprises the determination of the expression profile of a biomarker indicative for said disease. The present invention further relates to a molecule for detecting said biomarker for diagnosing and/or prognosing a neurodegenerative disease. It also relates to means for diagnosing and/or prognosing a neurodegenerative disease and a kit for diagnosing and/or prognosing a neurodegenerative disease.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

65.

ISOLATION OF MESENCHYMAL STEM CELLS

      
Application Number EP2011059393
Publication Number 2011/154403
Status In Force
Filing Date 2011-06-07
Publication Date 2011-12-15
Owner
  • EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKLINIKUM (Germany)
  • BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Aicher, Wilhelm
  • Angres, Brigitte

Abstract

The present invention relates to the use of a peptide selected from the group comprising laminin-1, collagen-1, collagen-3, collagen-4, tenascin, thrombospondin-1, osteopontin, fibronectin, vitronectin, or fragments or mixtures of these, for isolating and/or identifying mesenchymal stem cells (MSC), in particular of peptide fragments of these peptides. The invention furthermore relates to the use of these peptides/peptide fragments in the treatment of wounds, injuries and/or degenerated tissue.

IPC Classes  ?

  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • A61K 38/39 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
  • C07K 14/52 - CytokinesLymphokinesInterferons
  • A61K 38/19 - CytokinesLymphokinesInterferons

66.

METHOD FOR OPERATING A DEVICE FOR PROCESSING MATERIAL, AND DEVICE

      
Application Number EP2011001571
Publication Number 2011/120672
Status In Force
Filing Date 2011-03-29
Publication Date 2011-10-06
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Blug, Andreas
  • Abt, Felix
  • Nicolosi, Leonardo

Abstract

The invention relates to a method for operating a device for material processing workpieces by means of lasers (10), in particular a laser welding device, according to which method at least one optical feature characterizing the process is detected by at least one detection means (17) and at least one control parameter (P) for controlling the process energy formula (II) is generated by at least one data processing unit (19) using the control signal formula (I) derived from the optical feature. In order to provide a method for material processing by means of lasers, in which a process control is carried out in a simple manner for preventing negative effects on the processed workpiece (i), said control being stable despite a limited range of values of the control signal formula (I), in the sense that said control return to the process energy formula (II) at any time wherein the feature characterizing the process changes state, and, as long as the process remains near the required process energy formula (II), the control has high quality, according to the invention an optical feature having a transition between at least two states for at least one particular value of the process energy formula (II) is used for the method, and the process energy formula (II) is controlled at a controlled amplitude by considering the history (H) of the control signal formula (I) and/or the control parameter (P) for the method.

IPC Classes  ?

  • B23K 26/03 - Observing, e.g. monitoring, the workpiece
  • B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing

67.

A PASSIVE TERAHERTZ RADIATION SOURCE

      
Application Number EP2009004258
Publication Number 2010/142313
Status In Force
Filing Date 2009-06-12
Publication Date 2010-12-16
Owner BADEN-WÜRTTEMBERG STIFTUNG GGMBH (Germany)
Inventor
  • Dekorsy, Thomas
  • Klatt, Gregor
  • Bastian, Georg
  • Huska, Klaus

Abstract

The invention concerns a passive terahertz radiation source configured to emit electromagnetic radiation having frequency in the range of 10 GHz to 50 THz and a method for generating a terahertz radiation. The passive terahertz radiation source comprises: a source of a pulsed excitation light; an emitter comprising one or more emitter elements, each emitter element comprising a semiconductor layer being arranged such that at least a portion of a first major surface of said semiconductor layer is exposed to the excitation light, wherein each emitter element is configured such that upon exposure to the excitation light, a gradient of the charge carrier density is generated in the semiconductor layer in the area of transition between a first area of the semiconductor layer and a second area of the semiconductor layer, the gradient being substantially parallel to the first major surface of the semiconductor layer.

IPC Classes  ?

  • H01S 1/02 - Masers, i.e. devices using stimulated emission of electromagnetic radiation in the microwave range solid
  • G02F 2/02 - Frequency-changing of light, e.g. by quantum counters