The invention relates to a coherent single photon source (100) comprising: a nanodiamond (120) having a quantum emitter (140), wherein the nanodiamond (120) and the quantum emitter (140) are designed and configured such that the quantum emitter (140) emits coherent, indistinguishable photons (160). The invention further relates to a system (300) comprising: a first coherent single photon source (101); and a second coherent single photon source (102); wherein the first coherent single photon source (101) and the second coherent single photon source (102) are designed and configured such that photons (160) emitted from a first quantum emitter (151) of a first nanodiamond (121) of the first coherent single photon source (101) are indistinguishable from photons (160) emitted from a second quantum emitter (152) of a second nanodiamond (122) of the second coherent single photon source (102).
The invention relates to a quantum memory unit (100) comprising: a nanodiamond (120) having a quantum emitter (140), wherein an electron spin of the quantum emitter (140) is coupled to a spin object (170) inside or outside of the nanodiamond (120); wherein a coupling rate of the electron spin to the spin object (170) is larger than a decoherence rate of the electron spin; and wherein the spin object (170) is designed and configured such that quantum information can be stored therein, retrieved from it; and / or that a quantum state of the spin object (170) can be manipulated.
The invention relates to a measuring device and a method for detecting at least one object and/or for determining an object distance, e.g., for use in road traffic. The measuring device can comprise: a light source for emitting light with a predetermined coherence length; a beam splitter for splitting the emitted light into measuring and reference beams; a transfer unit that converts the reference beam into a plurality of sub-reference beams; an image data acquisition unit for acquiring image data resulting from a superposition of the sub-reference beams with an object beam comprising at least a part of the measuring beam that was scattered and/or reflected by the at least one object; and an evaluation unit for evaluating the image data, wherein the reference beam transfer unit comprises spatially separated optical paths having different optical lengths, along which the sub-reference beams are guided to the image data acquisition unit.
G06V 20/58 - Reconnaissance d’objets en mouvement ou d’obstacles, p. ex. véhicules ou piétonsReconnaissance des objets de la circulation, p. ex. signalisation routière, feux de signalisation ou routes
4.
METHOD AND APPARATUS FOR PROCESS MONITORING DURING PRODUCTION OF A FINISHED PART FROM A HOT-CROSSLINKING MATERIAL IN A PRIMARY SHAPING PROCESS
The invention relates to a method for process monitoring during production of a finished part (112) in a primary shaping process. The method comprises the following steps: a) providing at least one mould (114) designed for the primary shaping process, wherein the mould (114) has at least one cavity (116) for receiving at least one starting material for the hot-crosslinking material, and wherein an apparatus for determining a mould internal pressure is also integrated into the mould (114); b) heating the mould (114); c) introducing the at least one starting material for the hot-crosslinking material into the cavity (116) under pressure such that the finished part (112) is produced; d) detecting a progression of the mould internal pressure occurring in step c); e) differentiating, at least once or at least twice, the progression of the mould internal pressure in order to determine at least one derivative selected from the group consisting of: the first-order derivative and the second-order derivative; and f) characterising a progression of a chemical crosslinking reaction by means of at least one derivative selected from the group consisting of: the first-order derivative and the second-order derivative.
The invention relates to p38 MAP kinase inhibitors of formula (I) as shown in the description for use in the treatment of colorectal cancer. Further, the invention relates to p38 MAP kinase inhibitors specifically mentioned in the description, and a pharmaceutical composition comprising said inhibitors.
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/175 - Amides, p. ex. acides hydroxamiques ayant le groupe N-C(O)-N ou N-C(S)-N, p. ex. urée, thiourée, carmustine ayant le groupe , N-C(O)-N=N- ou , p. ex. carbonohydrazides, carbazones, semicarbazides, semicarbazonesLeurs thio-analogues
A61K 31/397 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à quatre chaînons, p. ex. azétidine
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 31/445 - Pipéridines non condensées, p. ex. pipérocaïne
C07C 13/00 - Hydrocarbures cycliques contenant des cycles autres que des cycles aromatiques à six chaînons, avec ou sans cycles aromatiques à six chaînons
C07D 205/00 - Composés hétérocycliques comportant des cycles à quatre chaînons ne contenant qu'un atome d'azote comme unique hétéro-atome du cycle
C07D 207/00 - Composés hétérocycliques contenant des cycles à cinq chaînons, non condensés avec d'autres cycles, ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle
C07D 265/00 - Composés hétérocycliques contenant des cycles à six chaînons comportant un atome d'azote et un atome d'oxygène comme uniques hétéro-atomes du cycle
The invention relates to thermoresponsive wound dressings having thermally switchable adhesion/de-adhesion, comprising: a carrier material and an adhesive composition applied to a surface of the carrier material, wherein the adhesive composition comprises: at least one vinyl alcohol/copolymer of the below formula (I): wherein x, with respect to any fatty acid unit, independently represents an integer from 10 to 18, wherein the copolymer according to formula (I) is present as a melt at body temperature, which melt adheres to wounds and skin, and when cooled to a temperature above the freezing point of water, the crystallisation of the copolymer according to formula (I) brings about de-adhesion of the wound dressing. The invention further relates to the use of said thermoresponsive wound dressing for wound healing or for protecting skin injuries and skin disorders.
A method for preparing a stack of dielectric layer on a substrate. A substrate is provided and a first layer of liquid is printed onto a surface of the substrate. A first dielectric layer is formed by solidifying the first layer of liquid and a second layer of liquid is printed onto the first dielectric layer. A second dielectric layer is formed by solidifying the second layer of liquid. The liquid includes dielectric constituents and the liquid is printed such that droplets having a volume of less than one hundred nanoliters are locally deposited per square millimeter on the surface of the substrate.
B05D 7/00 - Procédés, autres que le flocage, spécialement adaptés pour appliquer des liquides ou d'autres matériaux fluides, à des surfaces particulières, ou pour appliquer des liquides ou d'autres matériaux fluides particuliers
G02B 1/00 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques
B05D 3/06 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliquésTraitement ultérieur des revêtements appliqués, p. ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides par exposition à des rayonnements
9.
GAS-CONTAINING SURFACE COVER, ARRANGEMENT, AND USE
The present invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.
B63B 59/04 - Moyens pour éviter la salissure de la coque
F16L 58/02 - Protection des tuyaux ou des accessoires pour tuyaux contre la corrosion ou l'entartrage au moyen de revêtements internes ou externes
B05D 5/08 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface antifriction ou anti-adhésive
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
C07D 405/06 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 405/14 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
B32B 3/30 - Produits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche continue dont le périmètre de la section droite a une allure particulièreProduits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche comportant des cavités ou des vides internes caractérisés par une couche comportant des retraits ou des saillies, p. ex. des gorges, des nervures
A peptide derivative selected from a list of peptide derivatives with a sequence derived from human serum albumin fragment EPI-X4 is provided, which binds to CXCR4 with about 1000-fold stronger efficiency than EPI-X4. The peptide derivatives comprise length variants as well as modifications by length variants, D-amino acids, coupling of fatty acids, cholesterol or polymers, acetyl substitutions of amino groups, amination of carboxyl groups. Further provided are pharmaceutical compositions of the peptide derivative.
C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/24 - Composés organiques, p. ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p. ex. cyclométhicone ou phospholipides
A61K 47/28 - Stéroïdes, p. ex. cholestérol, acides biliaires ou acide glycyrrhétinique
A61K 47/32 - Composés macromoléculaires obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. carbomères
A61K 47/42 - ProtéinesPolypeptidesLeurs produits de dégradationLeurs dérivés p. ex. albumine, gélatine ou zéine
The present invention relates to an optical device (1), having ˗ at least one first surface (3) comprising at least one first nanostructure (5), wherein ˗ the at least one first nanostructure (5) comprises at least one conductive polymer material, wherein ˗ the optical device (1) comprises at least one conductor (7) in electrical contact to the at least one first nanostructure (5), wherein ˗ the at least one first nanostructure (5) is adapted to change its dielectric function when an electric quantity of the at least one conductor (7) is changed.
G02B 1/00 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques
G02B 5/00 - Éléments optiques autres que les lentilles
G02F 1/17 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des éléments à absorption variable non prévus dans les groupes
12.
SYSTEM FOR MONITORING THREE-DIMENSIONAL CELL CULTURES
The present invention relates to a system for monitoring (the metabolism of) three-dimensional cell cultures, an organ-on-chip device comprising the system, and a method for monitoring (the metabolism of) cell cultures, preferably three-dimensional cell cultures.
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
A peptide derivative selected from a list of peptide derivatives with a sequence derived from human serum albumin fragment EPI-X4 is provided, which binds to CXCR4 with about 1000-fold stronger efficiency than EPI-X4. The peptide derivatives comprise length variants as well as modifications by length variants, D-amino acids, coupling of fatty acids, cholesterol or polymers, acetyl substitutions of amino groups, aminations of carboxyl groups. Further provided are pharmaceutical compositions of the peptide derivative.
The invention relates to a 3D-printed actuatable optical device and a method for fabricating the actuatable optical device. The method comprises the following steps:
forming a three-dimensional structure (50) of the optical device (100) with the aid of a 3D printer in such a way that the three-dimensional structure (50) has:
at least one optical element, and
at least one microfluidic cavity (4) for accommodating a magnetic substance (6);
filling the at least one microfluidic cavity (4) with the magnetic substance (6).
The invention relates to a 3D-printed actuatable optical device and a method for fabricating the actuatable optical device. The method comprises the following steps:
forming a three-dimensional structure (50) of the optical device (100) with the aid of a 3D printer in such a way that the three-dimensional structure (50) has:
at least one optical element, and
at least one microfluidic cavity (4) for accommodating a magnetic substance (6);
filling the at least one microfluidic cavity (4) with the magnetic substance (6).
The invention further relates to the use of a magnetizable fluid for fabricating a magnetically actuatable optical device.
B29C 64/268 - Agencements pour irradiation par faisceaux laserAgencements pour irradiation par faisceaux d’électrons [FE]
B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
B29C 64/135 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque la source d’énergie étant concentrée, p. ex. lasers à balayage ou sources lumineuses focalisées
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
16.
NOVEL DIAGNOSTIC MARKER FOR CREUTZFELDT-JAKOB DISEASE AND ALZHEIMER'S DISEASE
The present invention relates to method of diagnosis of diseases associated with synaptic degeneration, in particular of Creutzfeldt-Jakob-Disease or Alzheimer's Disease, and to the use of β-synuclein as a biomarker for diagnosing or assessing the status of diseases associated with synaptic degeneration, in particular of Creutzfeldt-Jakob-Disease or Alzheimer's Disease..
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
The present invention relates to structured, gas-holding surfaces for improving the friction-reducing properties of gas layers held under a liquid and for the simultaneous suppression of turbulence. The present invention furthermore relates to a device comprising this structured, gas-holding surface and to the use of this structured, gas-holding surface.
B08B 17/06 - Procédés pour empêcher la salissure pour empêcher le dépôt de crasses ou de poussières en donnant aux objets susceptibles de s'encrasser une conformation ou un agencement particulier
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B63B 59/04 - Moyens pour éviter la salissure de la coque
18.
Gas-containing surface cover, arrangement, and use
The present invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.
B63B 59/04 - Moyens pour éviter la salissure de la coque
F16L 58/02 - Protection des tuyaux ou des accessoires pour tuyaux contre la corrosion ou l'entartrage au moyen de revêtements internes ou externes
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B32B 3/30 - Produits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche continue dont le périmètre de la section droite a une allure particulièreProduits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche comportant des cavités ou des vides internes caractérisés par une couche comportant des retraits ou des saillies, p. ex. des gorges, des nervures
B05D 5/08 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface antifriction ou anti-adhésive
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p. ex. rifampine, thiothixène ou sparfloxacine
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
C07D 405/06 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 405/14 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
F16L 57/06 - Protection des tuyaux ou d'objets de forme similaire contre les dommages ou les usures internes ou externes contre l'usure
B05D 5/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface mate ou rugueuse
19.
Method of fabricating an imaging system and corresponding imaging system
A method of fabricating an imaging system as well as to a corresponding imaging system. The method includes providing a substrate; and forming, by means of a 3D-printing technique, a 3D structure on the substrate, wherein the forming of the 3D structure includes forming a stack of at least two diffractive optical elements in a single printing step.
The invention relates to a hand exoskeleton (10) for supporting the functionality of a hand, having: a flexible mounting module (16), which can be arranged on the back of the hand; and a plurality of finger modules (12), which can be connected to the mounting module (16), wherein each finger module of the plurality of finger modules (12) is designed to receive a corresponding finger of the hand, at least in sections; wherein the mounting module (16) furthermore has: a plurality of connection sections (54) for connecting the plurality of finger modules (12) to the mounting module (16), wherein a respective finger module of the plurality of finger modules (12) is connected to a corresponding connection section of the plurality of connection sections (54); and wherein the mounting module (16) is designed such that the connection sections are movable relative to each other.
A61F 5/01 - Dispositifs orthopédiques, p. ex. dispositifs pour immobiliser ou pour exercer des pressions de façon durable pour le traitement des os fracturés ou déformés, tels que éclisses, plâtres orthopédiques ou attelles
21.
DETERMINING VERSION INFORMATION OF A NETWORK SERVICE
Aspects of the application relate to a computer-implemented method, a computer program and a network security tool. The computer-implemented method is for determining version information of a network service. The method comprises providing a plurality of specified queries, and receiving an identifier of the network service. The method further comprises retrieving, using the identifier, a first one of the specified queries. The method further comprises querying the network service via the first specified query, wherein the first specified query includes a first task. The method further comprises receiving a response to the first specified query, and determining, based on the response, a first result indication that indicates whether the first task has been successfully carried out. The method further comprises determining first version information of the network service based on the first result indication, and providing the version information of the network service. The version information includes the first version information.
G06F 21/57 - Certification ou préservation de plates-formes informatiques fiables, p. ex. démarrages ou arrêts sécurisés, suivis de version, contrôles de logiciel système, mises à jour sécurisées ou évaluation de vulnérabilité
H04L 29/06 - Commande de la communication; Traitement de la communication caractérisés par un protocole
An area scanning confocal microscope includes a pattern generation unit configured to generate or produce a line pattern comprising a plurality of lines, for example a plurality of straight parallel lines; a projection unit comprising a microscope objective configured to project the line pattern onto an object through the microscope objective, wherein the focal plane in which the line pattern is projected or imaged is tilted at a tilting angle with respect to an optical axis of the microscope, the tilting angle being equal to or greater than 0° and smaller than 90°, for example between 30° and smaller than 85°; and an imaging unit comprising a two-dimensional image detector configured to capture within one image frame of the image detector an image of the projected line pattern.
09 - Appareils et instruments scientifiques et électriques
16 - Papier, carton et produits en ces matières
41 - Éducation, divertissements, activités sportives et culturelles
Produits et services
Compact discs; DVDs; Digital recording media; Data carriers; The aforesaid goods including for information material relating to: digitisation including digitisation in teaching, and in schools and education. Printed matter; Photographs; Instructional and teaching material (except apparatus); The aforesaid goods including for information material relating to: digitisation including digitisation in teaching, and in schools and education. Education; Providing of training; Entertainment; Arranging and conducting events; Publication of information, other than for advertising purposes; Providing of electronic, non-downloadable publications for information purposes; The aforesaid service including in the field: digitisation including digitisation in teaching, and in schools and education.
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Advertising; Business management; Business administration; Office functions. Education; Providing of training; Entertainment; Sporting and cultural activities. Scientific and technological services and research and design relating thereto; Industrial analysis and research services; Design and development of computer hardware and software.
The present invention relates to structured gas-containing surfaces for improving the friction-reducing properties of gas layers held under a liquid and for the simultaneous suppression of turbulences. The present invention further relates to a device comprising said structured gas-containing surface and to the use of said structured gas-containing surface.
B08B 17/06 - Procédés pour empêcher la salissure pour empêcher le dépôt de crasses ou de poussières en donnant aux objets susceptibles de s'encrasser une conformation ou un agencement particulier
B63B 1/36 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des moyens mécaniques
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B63B 59/04 - Moyens pour éviter la salissure de la coque
The present invention relates to structured gas-containing surfaces for improving the friction-reducing properties of gas layers held under a liquid and for the simultaneous suppression of turbulences. The present invention further relates to a device comprising said structured gas-containing surface and to the use of said structured gas-containing surface.
B08B 17/06 - Procédés pour empêcher la salissure pour empêcher le dépôt de crasses ou de poussières en donnant aux objets susceptibles de s'encrasser une conformation ou un agencement particulier
B63B 1/36 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des moyens mécaniques
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B63B 59/04 - Moyens pour éviter la salissure de la coque
forming, by means of a 3D-printing technique, at least two imaging elements directly on the image sensor such that the imaging elements have a common focal plane located on the image sensor and each imaging element has a different focal length and field of view.
H04N 5/232 - Dispositifs pour la commande des caméras de télévision, p.ex. commande à distance
B33Y 80/00 - Produits obtenus par fabrication additive
G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Advertising; Business management; Business administration; Office functions. Education; Providing of training; Entertainment; Sporting activities; Cultural activities; Vocational guidance [education or training advice]; Vocational skills training (Provision of -); Arranging of workshops for vocational guidance; Arranging professional workshop and training courses; Organisation of conferences relating to vocational training; Consultancy relating to vocational skills training; Computerised training in career counselling; Providing on-line information and news in the field of employment training; Providing of information relating to training and vocational guidance (education or training advice); Arranging and conducting of exhibitions for educational purposes. Scientific and technological services and research and design relating thereto; Industrial analysis services; Industrial research; Design and development of computer hardware and computer software; Providing of information relating to digitisation; Providing of information relating to digitisation at work.
29.
METHOD OF FABRICATING AN IMAGING SYSTEM AND CORRESPONDING IMAGING SYSTEM
The present invention relates to a method of fabricating an imaging system as well as to a corresponding imaging system. The method comprises the steps of: - providing a substrate; - forming, by means of a 3D-printing technique, a 3D-structure (100) on the substrate, wherein the forming of the 3D-structure (100) comprises forming a stack of at least two diffractive optical elements (10) in a single printing step.
The present invention relates to a three-dimensional macroporous scaffold structure comprising cross-linked cationized bovine serum albumin. The invention also relates to a production method for the three-dimensional macroporous scaffold structure, to a method for culturing cells in the three-dimensional macroporous scaffold structure and to a kit comprising said three-dimensional macroporous scaffold structure.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
31.
A CONJUGATE COMPLEX FACILITATING THE TRANSPORT OF A CARGO THROUGH A MEDIUM
The present invention relates to conjugate complexes, comprising at least one biological entity, at least one cargo moiety, and at least one effector moiety that is capable of converting, degrading, and/or modifying a given medium, wherein the at least one cargo moiety and the at least one effector moiety are directly or indirectly coupled to the biological entity. The present invention further relates to uses thereof and methods for facilitating the transport of a cargo moiety through a given medium.
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p. ex. émulsion, particule, complexe d’inclusion, stent ou kit
A61K 47/64 - Conjugués médicament-peptide, médicament-protéine ou médicament-acide polyaminé, c.-à-d. l’agent de modification étant un peptide, une protéine ou un acide polyaminé lié par covalence ou complexé à un agent thérapeutiquement actif
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
C12N 7/00 - Virus, p. ex. bactériophagesCompositions les contenantLeur préparation ou purification
32.
Device for switchably influencing electromagnetic radiation, and method for obtaining such a device
A device for switchably influencing electromagnetic radiation includes a phase change material and an optically responsive structure. The phase change material is switchable between at least a first state and a second state. The first state and the second state have different electrical and/or magnetic properties. The optically responsive structure is in contact with the phase change material and has at least a first nanostructure and a second nanostructure. The first nanostructure is being different from the second nanostructure. The first nanostructure is optically responsive at a predetermined electromagnetic wavelength when the phase change material is in its first state, and non-responsive at the predetermined wavelength when the phase change material is in its second state. The second nanostructure is optically responsive at the predetermined electromagnetic wavelength when the phase change material is in its second state, and non-responsive at the predetermined wavelength when the phase change material is in its first state.
H01L 45/00 - Dispositifs à l'état solide spécialement adaptés pour le redressement, l'amplification, la production d'oscillations ou la commutation, sans barrière de potentiel ni barrière de surface, p.ex. triodes diélectriques; Dispositifs à effet Ovshinsky; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
G02F 1/01 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur
G02F 1/29 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de la position ou de la direction des rayons lumineux, c.-à-d. déflexion
33.
Method and device for producing microstructures on optical fibers
a) of the optical fiber (1) with photoresist (2); —orienting (S30) the optical fiber (1) and a writing beam of a 3D printer with respect to one another; —forming (S40) the at least one microstructure (5) by exposing the photoresist (2) to light with the aid of the 3D printer.
B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
B29C 64/135 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p. ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective caractérisés par la source d'énergie à cet effet, p. ex. par irradiation globale combinée avec un masque la source d’énergie étant concentrée, p. ex. lasers à balayage ou sources lumineuses focalisées
34.
METHOD FOR TREATING THE SURFACE OF A HARD METAL BODY AND FOR COATING THE TREATED HARD METAL BODY WITH A DIAMOND LAYER
The invention relates to a method for treating the surface (110) of a hard metal body (112). The method has the following steps: a) providing a hard metal body (112), said hard metal body (112) comprising at least one carbide phase of a metal of the 4th to 6th subgroup of the periodic table of elements and at least one binding metal; b) forming at least one low-carbon ternary phase comprising the metal of the carbide phase, the binding metal, and carbon in a surface zone (114) of the hard metal body (112); c) supplying carbon into the surface zone (114) over an outer surface (122), wherein the binding metal in the surface zone (114) is at least partly converted into a gas phase, recrystallized grains of the carbide phase are formed within the surface zone (114), and the binding metal transitions into a wetting agent (124) of the outer surface (122) of the surface zone (114) and is present in a surface zone (114) region (128) remote from the surface such that the binding metal is bound in the low-carbon ternary phase in intermediate spaces of the recrystallized grains; and d) converting the low-carbon ternary phase in intermediate spaces of the recrystallized grains in a surface zone (114) region (128) remote from the surface into a phase which stabilizes the binding metal; whereby a treated surface (138) of the hard metal body (112) is obtained. The invention additionally relates to a method for coating a hard metal body (130) treated in such a manner with at least one diamond layer (132).
C23C 28/00 - Revêtement pour obtenir au moins deux couches superposées, soit par des procédés non prévus dans un seul des groupes principaux , soit par des combinaisons de procédés prévus dans les sous-classes et
35.
MEASUREMENT SYSTEM AND METHOD FOR COMBINED CAPTURE OF THE SURFACE TOPOGRAPHY AND HYPERSPECTRAL IMAGING
The present invention relates, in particular, to a method and an apparatus for capturing topographic and spatially resolved, spectral properties of a surface to be examined. Here, the method comprises: producing an illumination pattern of a first measurement light with a multiplicity of wavelengths; imaging the illumination pattern of the first measurement light onto the surface to be examined by means of a chromatic objective in such a way that, by way of the chromatic objective, the illumination pattern is imaged in focus at different distances for different wavelengths of the multiplicity of wavelengths of the first measurement light; imaging the first measurement light radiated by the surface to be examined by means of the chromatic objective onto a confocal mask, which has a transmission pattern corresponding to the illumination pattern; spectrally splitting the first measurement light transmitted through the confocal mask; capturing a 2-dimensional intensity distribution of the spectrally split first measurement light with spatial resolution by means of the detector; ascertaining the topographic properties of the surface to be examined on the basis of the intensity distribution of the first measurement light captured by means of the detector; homogeneously illuminating the surface to be examined by means of a second measurement light with a multiplicity of wavelengths; imaging the second measurement light radiated by the surface to be examined by means of the chromatic objective onto the confocal mask; spectrally splitting the second measurement light transmitted through the confocal mask; capturing a 2-dimensional intensity distribution of the spectrally split second measurement light with spatial resolution by means of the detector; and ascertaining the spatially resolved, spectral properties of the surface to be examined on the basis of the intensity distribution of the second measurement light captured by means of the detector.
The invention relates to a microscope for the molecular spectroscopic analysis of a sample (2), having a beam path having at least one quantum cascade laser (QCL) (3) which emits an infrared (IR) radiation, a phase modulator (5) which is arranged between the QCL (3) and the sample (2), at least one optical element (6) which is arranged between the phase modulator (5) and the sample (2) and a sensor (4) which detects an IR radiation which is transmitted and/or reflected by the sample (2). The invention relates further to a method for the molecular spectroscopic analysis of a sample (2) comprising the steps of irradiating the sample (2) with an infrared (IR) radiation by means of a quantum cascade laser (QCL) (3), wherein the IR radiation is directed onto the sample (2) via a phase modulator (5) and at least one optical element (6), and detecting the IR radiation which is reflected and/or transmitted by the sample (2).
G01N 21/35 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge
The present invention relates to an optical device (100) and a use of the optical device (100). The optical device (100) comprises: —a source electrode (2); —a drain electrode (4); —a gap area (6) between the source electrode (2) and the drain electrode (4); —a cluster (8) being positioned in the gap area (6) for connecting and disconnecting the source electrode (2) and the drain electrode (4) and for changing optical and/or plasmonic properties of the gap area (6); and an optical coupling element (10) for bringing light into and out of the gap area (6).
G02F 1/03 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des céramiques ou des cristaux électro-optiques, p. ex. produisant un effet Pockels ou un effet Kerr
G02B 5/00 - Éléments optiques autres que les lentilles
H01L 51/05 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés au redressement, à l'amplification, à la génération d'oscillations ou à la commutation et ayant au moins une barrière de potentiel ou une barrière de surface; Condensateurs ou résistances à l'état solide, ayant au moins une barrière de potentiel ou une barrière de surface
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p. ex. calcul quantique ou logique à un électron
G02B 6/122 - Éléments optiques de base, p. ex. voies de guidage de la lumière
38.
METHOD OF FABRICATING A MULTI-APERTURE SYSTEM FOR FOVEATED IMAGING AND CORRESPONDING MULTI-APERTURE SYSTEM
The present invention relates to a method of fabricating a multi-aperture system (100) for foveated imaging as well as to a corresponding multi-aperture system (100). The method comprises the steps of: - providing an image sensor (1); and - forming, by means of a 3D-printing technique, at least two imaging elements (11 -14) directly on the image sensor (1 ) such that the imaging elements (11 -14) have a common focal plane located on the image sensor (1) and each imaging element (11 - 14) has a different focal length and/or field of view.
The invention relates to methods for producing hydrogels for reversibly immobilising glycoproteins and/or cells on the hydrogel, involving lectins being coupled to the hydrogel, corresponding lectin-coupled hydrogels, the use thereof in 3D cell culture, and corresponding methods for reversibly immobilising glycoproteins and/or cells on such hydrogels.
C12N 11/04 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique piégées à l’intérieur du support, p. ex. dans un gel ou dans des fibres creuses
C12N 11/06 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique attachées au support au moyen d'un agent de pontage
C12N 11/08 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique
C07K 17/04 - Peptides immobilisés sur, ou dans, un support organique piégés à l'intérieur du support, p. ex. dans un gel, dans une fibre creuse
C07K 17/06 - Peptides immobilisés sur, ou dans, un support organique liés au support au moyen d'un agent de pontage
C07K 17/08 - Peptides immobilisés sur, ou dans, un support organique le support étant un polymère synthétique
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
40.
METHOD AND DEVICE FOR SPATIALLY CONTROLLED PARALLEL TRANSFECTION - FLOATING WELLS
The present invention relates to floating wells comprised in a cell carrier, wherein the cell carrier comprises a solid carrier, and the floating wells are located on the surface of the solid carrier. Further, the present invention relates to a cell carrier comprising a solid carrier comprising on a surface a plurality of spots having a spot size X, and cells on the surface of the solid carrier, a manufacturing method of a cell carrier and the use of the cell carrier for solid phase transfection and for transduction with viruses.
The present invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.
B63B 59/04 - Moyens pour éviter la salissure de la coque
F16L 58/02 - Protection des tuyaux ou des accessoires pour tuyaux contre la corrosion ou l'entartrage au moyen de revêtements internes ou externes
B05D 5/08 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface antifriction ou anti-adhésive
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B32B 3/30 - Produits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche continue dont le périmètre de la section droite a une allure particulièreProduits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche comportant des cavités ou des vides internes caractérisés par une couche comportant des retraits ou des saillies, p. ex. des gorges, des nervures
F16L 57/06 - Protection des tuyaux ou d'objets de forme similaire contre les dommages ou les usures internes ou externes contre l'usure
B05D 5/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface mate ou rugueuse
42.
Method and device for producing an optical element having at least one functional region, as well as use of the device
filling the at least one microfluidic cavity (4) with the functional substance (6) for forming the at least one functional region.
In addition, the invention relates to a device for manufacturing an optical element (100) as well as a use of the device.
The invention relates to a method and a device for producing at least one microstructure (5) on an axial end (1a) of an optical fibre (1). The method comprises the following steps: - providing (S10) the optical fibre (1); - wetting (S20) the axial end (1a) of the optical fibre (1) with photoresist (2); - orienting (S30) the optical fibre (1) and a writing beam of a 3D printer with respect to one another; - forming (S40) the at least one microstructure (5) by exposing the photoresist (2) to light with the aid of the 3D printer.
The invention relates to a method and a sensor assembly (1) for obtaining distance information with respect to a surface (2) to be measured. The sensor assembly (1) is operated according to the confocal principle and has a lighting device (3) with at least one first light source (4a), and the light of the first light source is coupled into a lighting beam path, along which the light is first guided at least partly in the direction of the pertinent surface (2) and is focused into different focal points (18a) in order to then be detected in the form of received signals by at least one detector (10a) of a detection device (20) after being reflected on the surface to be measured. The aim of the invention is to provide a method and a sensor assembly (1) which ensure a faster supply of robust depth information at a sufficient depth resolution. This is achieved by coupling transmission signals of a plurality of narrow-band light sources (4a, 4b) into the lighting beam path in the form of light, each transmission signal being focused onto different focal points (18a, 18b), and differentiating between signals originating from different light sources (4a, 4b) using at least one unique modulation pattern. By using filter elements, a high resistance to stray light can be achieved.
A device with switchable, chiral optical characteristics, has a first chiral arrangement with a first arrangement layer with at least one first nanostructure and a second arrangement layer with at least one second nanostructure. The first nanostructure and the second nanostructure are arranged relative to one another such that the chiral arrangement is chiral. A switching material with switchable dielectric characteristics is arranged between the first arrangement layer and the second arrangement layer.
G02B 1/00 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques
G02B 5/00 - Éléments optiques autres que les lentilles
G02F 1/01 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur
G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
The present invention relates to an optical device (100) and a use of the optical device (100). The optical device (100) comprises: - a source electrode (2); - a drain electrode (4); - a gap area (6) between the source electrode (2) and the drain electrode (4); - a cluster (8) being positioned in the gap area (6) for connecting and disconnecting the source electrode (2) and the drain electrode (4) and for changing optical and/or plasmonic properties of the gap area (6); and an optical coupling element (10) for bringing light into and out of the gap area (6).
G02B 5/00 - Éléments optiques autres que les lentilles
H01L 51/05 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives spécialement adaptés au redressement, à l'amplification, à la génération d'oscillations ou à la commutation et ayant au moins une barrière de potentiel ou une barrière de surface; Condensateurs ou résistances à l'état solide, ayant au moins une barrière de potentiel ou une barrière de surface
The invention relates to a microscope (1) for the molecular spectroscopic analysis of a sample (2), comprising a beam path having at least one quantum cascade laser (QCL) (3) which emits an infrared (IR) radiation, a phase modulator (5) which is arranged between the QCL (3) and the sample (2), at least one optical element (6) which is arranged between the phase modulator (5) and the sample (2), and a sensor (4) which detects IR radiation transmitted and/or reflected by the sample (2). The invention further relates to a method for the molecular spectroscopic analysis of a sample (2), having the steps of irradiating the sample (2) with infrared (IR) radiation by means of a quantum cascade laser (QCL) (3), said IR radiation being deflected onto the sample via a phase modulator (5) and at least one optical element (6), and detecting the IR radiation reflected and/or transmitted by the sample (2).
Optical system and method for the provision of at least one high-frequency modulated light pulse having a pump light source for the provision of high-frequency pump light pulses; an optical resonator having a coupling element for coupling the pump light pulses into the resonator and a decoupling element for decoupling the at least one high-frequency modulated light pulse from the resonator and an optically non-linear frequency conversion medium arranged in the resonator for transforming the pump light pulses in each case into two conversion light pulses and one residual pump light pulse. The resonator comprises a feedback arm for at least one of the two conversion light pulses and/or the residual pump light pulse, in which an optically non-linear feedback medium is arranged for the optical modulation of the at least one conversion light pulse and/or the residual pump light pulse.
H01S 3/108 - Commande de l'intensité, de la fréquence, de la phase, de la polarisation ou de la direction du rayonnement, p. ex. commutation, ouverture de porte, modulation ou démodulation par commande de dispositifs placés dans la cavité utilisant des dispositifs optiques non linéaires, p. ex. produisant une diffusion par effet Brillouin ou Raman
H01S 3/094 - Procédés ou appareils pour l'excitation, p. ex. pompage utilisant le pompage optique par de la lumière cohérente
G02F 1/139 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des cristaux liquides, p. ex. cellules d'affichage individuelles à cristaux liquides caractérisés par l'effet électro-optique ou magnéto-optique, p. ex. transition de phase induite par un champ, effet d'orientation, interaction entre milieu récepteur et matière additive ou diffusion dynamique basés sur des effets d'orientation où les cristaux liquides restent transparents
The present invention relates to a system and a method for distance measurement. The system for distance measurement comprises - a multiple-wavelength holography module (100) for detecting a holography measurement data set for at least one measurement point on the basis of at least one synthetic wavelength, the multiple-wavelength holography module (100) having: - at least two holography light sources (110, 112, 114, 116) for generating at least two coherent holography light beams having different wavelengths, - at least one beam splitter (124, 160) for splitting each holography light beam into an object light beam (155) and a reference light beam (135), and - at least one diffraction element (134, 138) for the dispersive diffraction of the reference light beams (135).
An aspect of the invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
F16L 58/02 - Protection des tuyaux ou des accessoires pour tuyaux contre la corrosion ou l'entartrage au moyen de revêtements internes ou externes
B32B 3/30 - Produits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche continue dont le périmètre de la section droite a une allure particulièreProduits stratifiés comprenant une couche ayant des discontinuités ou des rugosités externes ou internes, ou une couche de forme non planeProduits stratifiés comprenant une couche ayant des particularités au niveau de sa forme caractérisés par une couche comportant des cavités ou des vides internes caractérisés par une couche comportant des retraits ou des saillies, p. ex. des gorges, des nervures
B05D 5/08 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface antifriction ou anti-adhésive
F16L 57/06 - Protection des tuyaux ou d'objets de forme similaire contre les dommages ou les usures internes ou externes contre l'usure
B05D 5/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface mate ou rugueuse
The invention relates to a filtration-active fuel cell and to the use thereof in the treatment and processing of fluids, in particular liquids, wherein the filtration-active layer of a membrane filter is simultaneously used as an anode of a fuel cell.
The present invention relates to a method for solid phase transfection of at least one protein and at least one nucleic acid molecule into at least one cell comprising the step of providing a solid carrier containing at least one spot comprising a transfection reagent, at least one protein and the at least one nucleic acid molecule as well as to a solid carrier containing at least one spot comprising a transfection reagent, at least one protein and the at least one nucleic acid molecule.
The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.
C07K 14/415 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de végétaux
C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales
C12N 9/06 - Oxydoréductases (1.), p. ex. luciférase agissant sur des composés contenant de l'azote comme donneurs (1.4, 1.5, 1.7)
54.
A METHOD FOR AUTOMATED PLATFORM AND/OR REFERENCE OBJECT INDEPENDENT ACQUISITION OF POSITIONAL INFORMATION AND LOCALIZATION OF OBJECTS OF INTEREST IN A MICROSCOPE
The present invention relates to microscopic methods and respective apparatuses and/or systems for automated platform and/or reference object independent multidimensional localization of objects of interest as well as microscopic methods and respective apparatuses for automated platform and/or reference object independent acquisition of positional data of objects of interest. According to an aspect, there is provided a method for obtaining positional data of at least one object of interest within a probe by using a microscope comprising determining the positions of at least two reference markings in at least one image obtained by the microscope; determining a reference coordinate system associated with said reference markings based on the determined positions of the reference markings and data concerning the position of a probe positioning device of the microscope and determining positional information of one or more objects of interest in the reference coordinate system. The positional information may used by another microscope to re-locate objects of interest. According to another aspect, which is particularly applicable for highly accurate, fine adjustment of positional information and/or object location, a method for obtaining positional information and/or object location is proposed, which relies on detecting specific target objects and/or regions and/or patterns within the image of the probe and using the detected target objects and/or regions and/or patterns for correcting positional data of objects of interest (hits). This method may be combined with any of the above described methods according to aspects of the invention.
The present invention relates to a system for the caging and controlled release of at least one protein of interest, said system comprising e.g. a phytochrome B that is coupled to a capture reagent and e.g. a phytochrome interacting factor to which the at least one protein of interest is coupled. The present invention further relates to a method for the caging and controlled release of at least one protein of interest, said method using said system, as well as a kit comprising e.g. a phytochrome B that is coupled to a capture reagent and e.g. a phytochrome interacting factor that is coupled to a binding domain. Moreover, the present invention relates to the use of said system for the controlled release of at least one protein of interest. The system and method of the present invention can be used for the purification of the protein of interest.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
56.
SPECIFIC INHIBITORS OF PROTEIN P21 AS THERAPEUTIC AGENTS
The present invention relates to novel inhibitors of p21. These inhibitors are useful as therapeutic agents for promoting cell regeneration and in the treatment of cancer. Improvement of cell regeneration is particularly desirable in patients of old age or in patients suffering from chronic diseases, acute or chronic injuries.
C07D 219/14 - Composés hétérocycliques contenant les systèmes cycliques de l'acridine ou de l'acridine hydrogénée avec des radicaux hydrocarbonés, substitués par des atomes d'azote, liés à l'atome d'azote du cycle
C07D 311/58 - Benzo [b] pyrannes non hydrogénés dans le carbocycle avec des substituants autres que des atomes d'oxygène ou de soufre en position 2 ou 4
C07D 221/14 - Aza-phénalènes, p. ex. naphtalimide-1, 8
C07C 233/65 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant les atomes d'azote des groupes carboxamide liés à des atomes d'hydrogène ou à des atomes de carbone de radicaux hydrocarbonés non substitués
A61K 31/4985 - Pyrazines ou pipérazines condensées en ortho ou en péri avec des systèmes hétérocycliques
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
A61K 31/473 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. acridines, phénantridines
A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
The invention relates to a method for operating a laser welding device for welding workpieces by means of a laser beam, in which method a change in an optically detectable feature that accompanies a change in at least one first controlled variable of the welding process is detected by means of at least one detection means, and at least a first manipulated variable for processing by at least one control device is produced by at least one data processing unit on the basis of the change in the feature. The invention also relates to a device for carrying out such a method. In order to provide a laser welding device and a method for operating a laser welding device for welding workpieces that adjust themselves to the production conditions and at the same time minimize the occurrence of weld defects, it is proposed that, when the change in a feature that can be optically detected occurs, first of all the first manipulated variable is selected from a plurality of possible first manipulated variables and changed according to process requirements and that, in order to keep a second controlled variable of the welding process substantially constant, at least one further manipulated variable that is different from the selected first manipulated variable is changed for correspondingly controlling the second controlled variable.
The present invention relates to a system for the light-regulated expression of a transgene in a mammalian cell which can repeatedly and reversibly be activated and inactivated by illumination with light, based on the use of a split transcription factor that is present in the nucleus. The present invention further relates to an isolated nucleic acid molecule encoding said split transcription factor, a vector comprising said nucleic acid, a host cell comprising said system, isolated nucleic acid or vector, and a method for the light-regulated expression of a transgene in a cell, said method using the system of the present invention. Furthermore, the present invention relates to a kit for performing said method, and uses of the above.
The present invention relates to an environmentally friendly process for producing continuous micro- or supermicrofibres based on cellulose, which can be used for the production of filaments, textile fabrics, paper, filters, absorption materials, and hygiene and cosmetic articles.
D01F 2/02 - Filaments, ou similaires, artificiels, à un seul composant, formés de cellulose ou de dérivés de la celluloseLeur fabrication obtenus à partir de solutions de cellulose dans des acides, des bases ou des sels
D01F 2/28 - Filaments, ou similaires, artificiels, à un seul composant, formés de cellulose ou de dérivés de la celluloseLeur fabrication à partir de dérivés de la cellulose à partir d'esters ou d'éthers organiques de cellulose, p. ex. à partir d'acétate de cellulose
60.
USE OF A GAS-RETAINING LAYER WHICH IS ARRANGED ON A BODY THAT IS IMMERSIBLE IN A LIQUID OR WETTABLE BY THE LIQUID
AbstractA gas-retaining surface covering for a body that can be placed in contact with a liquid, and to a corresponding arrangement and to a use. In accordance with one aspect, there is provided a use of a gas-retaining layer which is arranged on a body that is immersible in a liquid or wettable by a liquid and which is in contact by way of a liquid-facing side with a liquid when the body is immersed in/wetted by the liquid. The gas-retaining layer has on the liquid-facing side recesses and/or protruding elements whose surfaces are hydrophobic at least regionally. A gas layer is retained in the immersed/wetted region of the gas-retaining layer that separates the liquid and the immersed/wetted region of the body from one another at least regionally. The gas-retaining layer may be divided into a multiplicity of sub-regions by fluid-impermeable partitions or the protruding elements may have a central surface region which is hydrophilic and which is surrounded by a hydrophobic surface region of the protruding elements. The gas-retaining layer allows for a gas volume to be retained on the body such that the body can be separated from the liquid surrounding the body by the gas-retaining layer or by the gas retained by the gas-retaining layer.CA 2866082 2019-04-30
B05D 5/08 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface antifriction ou anti-adhésive
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B63B 59/00 - Protection de la coque spécialement adaptée aux naviresAppareils de nettoyage spécialement adaptés aux navires
C09K 3/18 - Substances non couvertes ailleurs à appliquer sur des surfaces pour y minimiser l'adhérence de la glace, du brouillard ou de l'eauSubstances antigel ou provoquant le dégel pour application sur des surfaces
61.
USE OF A GAS-RETAINING LAYER WHICH IS ARRANGED ON A BODY THAT IS IMMERSIBLE IN A LIQUID OR WETTABLE BY THE LIQUID
A gas-retaining surface covering for a body that can be placed in contact with a liquid, and to a corresponding arrangement and to a use. In accordance with one aspect, there is provided a surface covering which comprises a gas-retaining layer which is designed and arranged so as to make contact by way of a liquid-facing side with the liquid. The gas-retaining layer has on the liquid-facing side protruding elements whose surfaces are hydrophobic, and wherein protruding elements have a central surface region which is hydrophilic and which is surrounded by a hydrophobic surface region of the protruding elements.
B05D 5/00 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers
C09K 3/18 - Substances non couvertes ailleurs à appliquer sur des surfaces pour y minimiser l'adhérence de la glace, du brouillard ou de l'eauSubstances antigel ou provoquant le dégel pour application sur des surfaces
62.
GAS-CONTAINING SURFACE COVER, ARRANGEMENT, AND USE
An aspect of the invention relates to a surface cover for a body which can be brought into contact with a liquid, comprising: a layer which at least partly contains gas and which is designed and arranged such that at least some sections of a layer face facing the liquid contacts the liquid; a gas-permeable layer which is arranged on the gas-containing layer on a face that faces the body and is opposite the face facing the liquid or which is integrally formed with the gas-containing layer; and a gas-supplying device which is connected to the gas-permeable layer such that gas can flow from the gas-supplying device to the gas-containing layer through the gas-permeable layer. The invention also relates to an arrangement and a use.
B05D 5/00 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers
B05D 5/08 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface antifriction ou anti-adhésive
B63B 1/38 - Autres moyens pour faire varier les caractéristiques hydrodynamiques inhérentes aux coques par réduction du frottement utilisant des bulles d'air ou des coussins d'air
B05D 5/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface mate ou rugueuse
B05D 5/04 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface où l'encre ou un autre liquide peuvent prendre
63.
DIAGNOSIS AND/OR PROGNOSIS OF PARKINSON'S DISEASE DEMENTIA
The present Invention provides a method for diagnosing and/or prognosing Parkinson's disease dementia (PDD) comprising the step of detecting O-glycosylation. in a protein comprising a Scr/Thr motive, in particular Serpin Al, and/or the level of sialic acid on a protein comprising a Ser/Thr motive, in particular Serpin Al. Further, the present invention relates to a molecule for detecting O-linked glycomoieties in a protein comprising a Ser/Thr motive, in particular Serpin Al, and/or glycosylated i so forms of a Ser/Thr motive comprising protein, in particular Serpin Al„ for use in the diagnosis and/or prognosis of Parkinson's disease dementia (PDD), Furthermore, the present invention relates to means for diagnosing and/or prognosing Parkinson's disease dementia (PDD) and a kit for diagnosing and/or prognosing Parkinson's disease dementia (PDD).
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
64.
DIAGNOSIS AND/OR PROGNOSIS OF A NEURODEGENERATIVE DISEASE
The present invention relates to a method for diagnosing and/or prognosing a neurodegenerative disease, particularly Parkinson's disease (PD) or Parkinson's disease dementia (PDD), which comprises the determination of the expression profile of a biomarker indicative for said disease. The present invention further relates to a molecule for detecting said biomarker for diagnosing and/or prognosing a neurodegenerative disease. It also relates to means for diagnosing and/or prognosing a neurodegenerative disease and a kit for diagnosing and/or prognosing a neurodegenerative disease.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
The present invention relates to the use of a peptide selected from the group comprising laminin-1, collagen-1, collagen-3, collagen-4, tenascin, thrombospondin-1, osteopontin, fibronectin, vitronectin, or fragments or mixtures of these, for isolating and/or identifying mesenchymal stem cells (MSC), in particular of peptide fragments of these peptides. The invention furthermore relates to the use of these peptides/peptide fragments in the treatment of wounds, injuries and/or degenerated tissue.
The invention relates to a method for operating a device for material processing workpieces by means of lasers (10), in particular a laser welding device, according to which method at least one optical feature characterizing the process is detected by at least one detection means (17) and at least one control parameter (P) for controlling the process energy formula (II) is generated by at least one data processing unit (19) using the control signal formula (I) derived from the optical feature. In order to provide a method for material processing by means of lasers, in which a process control is carried out in a simple manner for preventing negative effects on the processed workpiece (i), said control being stable despite a limited range of values of the control signal formula (I), in the sense that said control return to the process energy formula (II) at any time wherein the feature characterizing the process changes state, and, as long as the process remains near the required process energy formula (II), the control has high quality, according to the invention an optical feature having a transition between at least two states for at least one particular value of the process energy formula (II) is used for the method, and the process energy formula (II) is controlled at a controlled amplitude by considering the history (H) of the control signal formula (I) and/or the control parameter (P) for the method.
The invention concerns a passive terahertz radiation source configured to emit electromagnetic radiation having frequency in the range of 10 GHz to 50 THz and a method for generating a terahertz radiation. The passive terahertz radiation source comprises: a source of a pulsed excitation light; an emitter comprising one or more emitter elements, each emitter element comprising a semiconductor layer being arranged such that at least a portion of a first major surface of said semiconductor layer is exposed to the excitation light, wherein each emitter element is configured such that upon exposure to the excitation light, a gradient of the charge carrier density is generated in the semiconductor layer in the area of transition between a first area of the semiconductor layer and a second area of the semiconductor layer, the gradient being substantially parallel to the first major surface of the semiconductor layer.
