Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.
Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured, showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray-like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating clement for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices in the nature of a system comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction sold as a unit. Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.
4.
Ocular surface interferometry (OSI) for imaging, processing, and/or displaying an ocular tear film
Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.
Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
G02B 26/02 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the intensity of light
7.
Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film
Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
G02B 26/02 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the intensity of light
9.
Ocular tear film peak detection and stabilization detection systems and methods for determining tear film layer characteristics
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
Goods & Services
Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Printed instructional, educational and teaching materials in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction.
11.
Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film
Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
G02B 26/02 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the intensity of light
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
13.
Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on dry eye tear film characteristic analysis and dry eye symptoms
Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.
Background reduction apparatuses and methods of ocular surface interferometry (OSI) employing polarization for imaging, processing, and/or displaying an ocular tear film
Background reduction apparatuses and methods of Ocular Surface Interferometry (OSI) employing polarization are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT) and can be used to evaluate and potentially diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in at least one image. The at least one image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
Apparatuses and methods for determining tear film break-up time and/or for detecting lid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms
Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.
Apparatus and methods for treating dry eye include an energy source configured to apply energy to an obstruction located in a meibomian gland of a patient's eyelid. The apparatus also comprises an insulator configured to be positioned between a rear portion of the patient's eyelid and a surface of the patient's eyeball. An inner surface of the insulator has a curvature greater than that of the patient's eyeball such that an air pocket is formed between the inner surface of the insulator and the patient's eyeball, wherein the air pocket provides additional insulation to reduce or eliminate an amount of heat due to the applied energy from the energy source from being conducted to the surface of the patient's eyeball, such that the applied energy does not cause the temperature to reach a temperature sufficient to cause damage to a corneal or scleral portion of the patient's eyeball.
A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
A61H 7/00 - Devices for suction-kneading massageDevices for massaging the skin by rubbing or brushing not otherwise provided for
A61F 7/12 - Devices for heating or cooling internal body cavities
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61F 7/02 - Compresses or poultices for effecting heating or cooling
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61H 15/00 - Massage by means of rollers, balls, e.g. inflatable, chains, or roller chains
A61B 18/08 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Computer hardware and software, and parts and accessories
therefor, for use with apparatus for analyzing, diagnosing,
and monitoring meibomian glands and eye disease, namely, dry
eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories
therefor, used for analyzing, diagnosing, and monitoring
meibomian glands and eye disease, namely, dry eye and
meibomian gland dysfunction; optical and photographic
apparatus and instruments, and parts and accessories
therefor, namely, interferometers and cameras, for
analyzing, diagnosing, and monitoring meibomian glands and
eye disease, namely, dry eye and meibomian gland
dysfunction; medical imaging apparatuses and devices
comprising optical lens, camera, lamp, LED, spectrometer,
used for analyzing, diagnosing, and monitoring meibomian
glands and eye disease, namely, dry eye and meibomian gland
dysfunction. Printed instructional, educational and teaching materials in
the field of meibography, meibomian gland imaging and eye
disease, namely, dry eye and meibomian gland dysfunction;
printed instructional, educational and teaching materials
for analysis, diagnosis, and monitoring of meibomian glands
and eye disease, namely, dry eye and meibomian gland
dysfunction. Education services, namely, classes, conferences, seminars,
workshops, in the field of meibography, meibomian gland
imaging, and eye disease, namely, dry eye and meibomian
gland dysfunction; education services, namely, providing
seminars, tutorials, workshops for analyzing, diagnosing,
and monitoring meibography, meibomian gland imaging, and eye
disease, namely, dry eye and meibomian gland dysfunction;
training services in the field of meibography, meibomian
gland imaging and eye disease, namely, dry eye and meibomian
gland dysfunction; training services, namely, providing
seminars, tutorials, workshops for analyzing, diagnosing,
and monitoring meibomian glands and eye disease, namely, dry
eye and meibomian gland dysfunction. Medical services, namely, providing medical analysis,
diagnosis, and monitoring of meibomian glands and eye
diseases and conditions; medical services, namely, providing
medical analysis, diagnosis, and monitoring of meibomian
glands and eye disease, namely, dry eye and meibomian gland
dysfunction; providing medical information related to
meibomian glands and eye disease, namely, dry eye and
meibomian gland dysfunction, for educational purposes.
18.
Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
G02B 26/02 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the intensity of light
19.
Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction
(2) Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction
(3) Printed instructional, educational and teaching materials namely, guides, manuals and pamphlets in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials namely, guides, manuals and pamphlets for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction (1) Education services, namely, classes, conferences, seminars, workshops, in the field of meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction
(2) Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Providing medical information related to meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction Printed instructional, educational and teaching materials in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction [ Education services, namely, classes, conferences, seminars, workshops, in the field of meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction ] [ Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Providing medical information related to meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes ]
22.
Ocular tear film peak detection and stabilization detection systems and methods for determining tear film layer characteristics
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.
APPARATUSES AND METHODS FOR DETECTING LID MARGIN CONTACT AND BLINK RATES, PARTICULARLY FOR DIAGNOSING, MEASURING, AND/OR ANALYZING DRY EYE CONDITIONS AND SYMPTOMS
Embodiments disclosed herein include devices, systems, and methods for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during blink rate related procedures.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.
Methods and apparatuses of treating meibomian glands are disclosed. The method comprises applying regulated heat to an eyelid to reach a temperature adequate to melt at least one obstruction within at least one meibomian gland. The method also comprises maintaining the regulated heat for a time period adequate to place the at least obstruction in the melted state. The method further comprises positioning a pressure application device into contact with the patient's eyelid and applying a pressure with the pressure application device over a substantial portion of the eyelid to express the at least one obstruction from the meibomian gland. An apparatus suitable to treat meibomian glands comprises a heater, a controller, and a pressure applicator configured to be placed into contact with the eyelid and apply a pressure over a substantial portion of the eyelid to express the at least one obstruction from the meibomian gland.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.
Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
29.
METHODS AND APPARATUSES FOR DETERMNING CONTACT LENS INTOLERANCE IN CONTACT LENS WEARER PATIENTS BASED ON DRY EYE TEAR FILM CHARACTERISTIC ANALYSIS AND DRY EYE SYMPTOMS
Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.
Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
G01B 11/25 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures by projecting a pattern, e.g. moiré fringes, on the object
33.
Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (IOP) in a patient to either prevent or treat open-angle glaucoma. Heat is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT). By loosening or relaxing clogs or other inhibitors in the trabecular meshwork, the outflow path for aqueous humor is increased or restored, which can lower IOP and either prevent or treat glaucoma. Force may also be applied to the patient's eye to apply pressure to the trabecular meshwork to further assist in the loosening or relaxing of clogs or other inhibitors in the trabecular meshwork.
A61H 1/00 - Apparatus for passive exercisingVibrating apparatusChiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones
Methods and apparatuses are disclosed for the diagnosis and removal of the devitalized and/or dead cell material formed in the lid margin to attempt to restore a normal lid margin. In this manner, the devitalized and/or dead cell material are removed or the amount present is reduced or no longer present to prevent, reduce, or affect the transport of lipid secreted by the meibomian glands to the tear film to reduce evaporative dry eye and improve dry eye conditions in patients. The diagnosis and removal of devitalized and/or dead cell material may be performed at desired intervals. Patients that suffer from conditions that block meibomian gland orifices, partial, infrequent, or inhibited blinking resulting in reduced lipid secretions from meibomian glands, and/or blockages in meibomian gland channels reducing secretion of lipids through the meibomian gland orifices may require more frequent diagnosis and treatment to remove devitalized and/or dead cell material.
Apparatuses and methods for determining tear film break-up time and/or for detecting lid margin contact and blink rates, particulary for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms
Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.
Apparatuses and methods of ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film
Apparatuses and methods employing ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film are disclosed. The apparatuses and methods can be employed for measuring tear film layer thickness (TFLT) of the ocular tear film, which includes lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). An imaging device is focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device is focused on the lipid layer of the tear film to capture a second image containing background signal(s) in the first image. The second image can be subtracted from the first image to reduce and/or eliminate background signal(s) in the first image to produce a resulting image that can be analyzed to measure tear film layer thickness (TFLT).
G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
38.
OPTICAL PHANTOMS FOR USE WITH OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES AND SYSTEMS CONFIGURED TO MEASURE TEAR FILM LAYER THICKNESS(ES), AND RELATED USES FOR CALIBRATION
Embodiments of the detailed description include optical phantoms for use with ocular surface interferometery (OSI) devices and systems configured to measure tear film layer thickness(es), and related use for calibration. The ocular surface interferometry (OSI) devices, systems, and methods can be used for imaging an ocular tear film and/or measuring a tear film layer thickness (TFLT) in a patient's ocular tear film. The OSI devices, systems, and methods can be used to measure the thickness of the lipid layer component (LLT) and/or the aqueous layer component (ALT) of the ocular tear film. "TFLT" as used herein includes LLT, ALT, or both LLT and ALT. "Measuring TFLT" as used herein includes measuring LLT, ALT, or both LLT and ALT. Imaging the ocular tear film and measuring TFLT can be used in the diagnosis of a patient's tear film, including but not limited to lipid layer and aqueous layer deficiencies.
A61B 3/14 - Arrangements specially adapted for eye photography
39.
APPARATUSES AND METHODS FOR DETERMINING TEAR FILM BREAK-UP TIME AND/OR FOR DETECTING LID MARGIN CONTACT AND BLINK RATES, PARTICULARLY FOR DIAGNOSING, MEASURING, AND/OR ANALYZING DRY EYE CONDITIONS AND SYMPTOMS
Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.
BACKGROUND REDUCTION APPARATUSES AND METHODS OF OCULAR SURFACE INTERFEROMETRY (OSI) EMPLOYING POLARIZATION FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM
Background reduction apparatuses and methods of Ocular surface interferometry (OSI) employing polarization are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT) and can be used to evaluate and potentially diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in at least one image. The at least one image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
G01B 11/06 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness for measuring thickness
41.
APPARATUSES AND METHODS OF OCULAR SURFACE INTERFEROMETRY (OSI) EMPLOYING POLARIZATION AND SUBTRACTION FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM
Apparatuses and methods employing ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film are disclosed. The apparatuses and methods can be employed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.
A61B 3/14 - Arrangements specially adapted for eye photography
42.
Background reduction apparatuses and methods of ocular surface interferometry (OSI) employing polarization for imaging, processing, and/or displaying an ocular tear film
Background reduction apparatuses and methods of Ocular surface interferometry (OSI) employing polarization are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT) and can be used to evaluate and potentially diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in at least one image. The at least one image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
A method of treating meibomian gland dysfunction is disclosed. The method includes directing RF energy to an internal portion of a meibomian gland, selectively targeting an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction, and expressing the obstruction from the duct of the meibomian gland. An apparatus for treating meibomian gland dysfunction is also disclosed. The apparatus comprises at least one RF electrode configured to direct RF energy to an internal portion of a meibomian gland located in an eyelid of an eye, the at least one RF electrode further configured to selectively target an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction. The apparatus also comprises at least one expressor configured to express the obstruction from the duct of the meibomian gland.
A61F 7/08 - Warming pads, pans or matsHot-water bottles
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibrationSuction-vibration massageMassage with moving diaphragms with electric or magnetic drive
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
A61H 39/08 - Devices for applying needles to such points, i.e. for acupuncture
A61H 15/00 - Massage by means of rollers, balls, e.g. inflatable, chains, or roller chains
A method of treating meibomian gland dysfunction is disclosed. The method includes directing RF energy to an internal portion of a meibomian gland, selectively targeting an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction, and expressing the obstruction from the duct of the meibomian gland. An apparatus for treating meibomian gland dysfunction is also disclosed. The apparatus comprises at least one RF electrode configured to direct RF energy to an internal portion of a meibomian gland located in an eyelid of an eye, the at least one RF electrode further configured to selectively target an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction. The apparatus also comprises at least one expressor configured to express the obstruction from the duct of the meibomian gland.
Methods of diagnosing meibomian gland dysfunction are disclosed. The methods may be standardized and provide an accurate diagnosis of whether meibomian gland dysfunction exists. In one embodiment, a method is provided that utilizes an evaluation tool to apply a force for a preselected period of time to at least one of a plurality of meibomian glands in two or more regions of a plurality of regions of an eyelid. A grade is assigned to the at least one meibomian gland of the plurality of meibomian glands in each of the two or more regions based on any secretion that is expressed from each meibomian gland. In this manner, a plurality of meibomian gland secretion grades is obtained. The plurality of meibomian gland secretion grades is indicative of the presence of meibomian gland dysfunction.
A method for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye. Light is directed to the lipid layer of a patient's eye with an illuminator that is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis.
A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
Methods of diagnosing meibomian gland dysfunction are disclosed. The methods may be standardized and provide an accurate diagnosis of whether meibomian gland dysfunction exists. In one embodiment, a method is provided that utilizes an evaluation tool to apply a force for a preselected period of time to at least one of a plurality of meibomian glands in two or more regions of a plurality of regions of an eyelid. A grade is assigned to the at least one meibomian gland of the plurality of meibomian glands in each of the two or more regions based on any secretion that is expressed from each meibomian gland. In this manner, a plurality of meibomian gland secretion grades is obtained. The plurality of meibomian gland secretion grades is indicative of the presence of meibomian gland dysfunction.
The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer. In order to facilitate ease of measurement, the patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the patient's eye.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Computer hardware and software, and parts and accessories therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices in the nature of a system comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction sold as a unit; Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction. (1) Education services, namely classes, conferences, seminars, workshops, in the field of eye disease, namely dry eye and meibomian gland dysfunction; education services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; training services in the field of eye disease, namely dry eye and meibomian gland dysfunction; training services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.
51.
Method and apparatus for treating meibomian gland dysfunction employing fluid jet
According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice. The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is it is applied to the exterior surface of the eyelid, proximate to the gland channel orifice, a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed. In an exemplary embodiment, the medium is water heated to a temperature of between about 42° C. and about 46° C. Depending on the particular type and composition of the obstruction, the fluid jet operates to melt or soften the obstruction and to milkingly move the corpus of the softened obstruction up the gland channel from the end opposite the meibomian gland orifice and out of the gland orifice. Repeated application of the heated fluid jet may also be necessary to soften and/or express the obstruction.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a TFLT.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
55.
OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES, SYSTEMS, AND METHODS FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM AND/OR MEASURING OCULAR TEAR FILM LAYER THICKNESS(ES)
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The mea-sured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first im-age. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the back-ground signal(s) present in the first image.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/14 - Arrangements specially adapted for eye photography
56.
OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES, SYSTEMS, AND METHODS FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM AND/OR MEASURING OCULAR TEAR FILM LAYER THICKNESS(ES)
There is provided ocular surface interferometry devices, systems, and methods for measuring ocular tear film layer thickness(es) (TFLT). In one method and apparatus, the optical wave interference of specularly reflected light and a background signal are captured from a region of interest of an ocular tear film in a first and second image respectively by an imaging device. The second image is subtracted from the first image to generate at least one resulting image containing the optical wave interference of the specularly reflected light from the region of interest of the ocular tear film with the background signal removed or reduced. A portion of the resulting image is converted from a portion of the region of interest into at least one color-based value, which is compared to a tear film layer optical wave interference model. The TFLT of the portion of the region of interest is measured.
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves
58.
OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES, SYSTEMS, AND METHODS FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM AND/OR MEASURING OCULAR TEAR FILM LAYER THICKNESS (ES)
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.
A01N 57/26 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-nitrogen bonds
59.
METHODS, APPARATUSES, AND SYSTEMS FOR REDUCING INTRAOCULAR PRESSURE AS A MEANS OF PREVENTING OR TREATING OPEN-ANGLE GLAUCOMA
Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (lOP) in a patient to either prevent or treat open-angle glaucoma. Heat or a combination of heat and force is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat alone or with force to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT).
The disclosure comprises a method for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking. Light is directed to the lipid layer of a patient's eye with an illuminator. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer. In order to facilitate ease of measurement, the patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the patient's eye.
Apparatus for measuring the relative thickness of the lipid layer of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking An illuminator directs light to the lipid layer of an eye The illuminator is a broad spectrum source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable The collector produces output representative of the specularly reflected light for further analysis, such as projection on to a high resolution monitor or computer analysis The patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the eye.
Method for measuring the relative thickness of the lipid layer of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking Light is directed to the lipid layer with an illuminator which is a broad spectrum source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable The collector produces an output representative of the specularly reflected light for further analysis, such as projection on to a high resolution monitor or computer analysis The patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the eye.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations for the prevention and treatment
of ocular disorders, namely, dry eye and meibomian gland
dysfunction; nutraceuticals for the prevention and treatment
of ocular disorders, namely, dry eye and meibomian gland
dysfunction; ophthalmic preparations, eye drops, and
medicated eye gels and medicated gels applied to the
meibomian glands used for the treatment of ocular disorders,
namely, dry eye and meibomian gland dysfunction; vitamins. Computer hardware and software, and parts and accessories
therefor, for use with analyzing, diagnosing, treating, and
monitoring eye disease, namely, dry eye and meibomian gland
dysfunction; optical and photographic apparatus and
instruments, and parts and accessories therefor, namely,
interferometers and cameras, for analyzing, diagnosing, and
monitoring eye disease, namely, dry eye and meibomian gland
dysfunction; medical imaging apparatuses and devices
comprising optical lens, camera, lamp, LED, spectrometer,
used for analyzing, diagnosing, and monitoring eye disease,
namely, dry eye and meibomian gland dysfunction; electronic
medical temperature controller, and parts and accessories
therefor, used primarily for temperature controller
purposes, namely, for delivering and controlling heat to
meibomian glands for use in treating eye disease, namely,
dry eye and meibomian gland dysfunction; electronic medical
pressure controller, and parts and accessories therefor,
used primarily for controlling pressure, namely, for
applying and controlling pressure to the meibomian glands
for use in treating eye disease, namely, dry eye and
meibomian gland dysfunction; electronic medical fluid
transfer controller, and parts and accessories therefor,
used primarily for controlling and transferring heated fluid
to the eye for use in treating eye disease, namely, dry eye
and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories
therefor, used for analyzing, diagnosing, treating, and
monitoring eye disease, namely, dry eye and meibomian gland
dysfunction; medical device, and parts and accessories
therefor, for expressing obstructions or occlusions from
meibomian glands; medical heater used primarily for medical
purposes, namely, for applying heat to a patient's eye and
related eye structure for treating eye diseases, namely, dry
eye and meibomian gland dysfunction; medical devices,
namely, medical contact lens used primarily for medical
purposes containing an electrical heating element for
applying heat to meibomian glands when installed on a
patient's eye for treating dry eye and meibomian gland
dysfunction. Printed instructional, educational and teaching materials in
the field of eye disease, namely, dry eye and meibomian
gland dysfunction; printed instructional, educational and
teaching materials for analysis, diagnosis, treatment, and
monitoring of eye disease, namely, dry eye and meibomian
gland dysfunction. Education services, namely, classes, conferences, seminars,
workshops, in the field of eye disease, namely, dry eye and
meibomian gland dysfunction; education services, namely,
providing seminars, tutorials, workshops for analyzing,
diagnosing, treating, and monitoring eye disease, namely,
dry eye and meibomian gland dysfunction; training services
in the field of eye disease, namely, dry eye and meibomian
gland dysfunction; training services, namely, providing
seminars, tutorials, workshops for analyzing, diagnosing,
treating, and monitoring eye disease, namely, dry eye and
meibomian gland dysfunction. Medical services, namely, providing medical analysis,
diagnosis, treatment, and monitoring of eye diseases and
conditions; medical services, namely, providing medical
analysis, diagnosis, treatment, and monitoring of dry eye
and meibomian gland dysfunction; providing medical
information related to eye disease, namely, dry eye and
meibomian gland dysfunction, for educational purposes.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Ophthalmic preparations, eye drops, and medicated eye gels
and medicated gels applied to the meibomian glands used for
the treatment of ocular disorders, namely, dry eye and
meibomian gland dysfunction. Computer hardware and software, and parts and accessories
therefor, for use with analyzing, diagnosing, treating, and
monitoring eye disease, namely, dry eye and meibomian gland
dysfunction; optical and photographic apparatus and
instruments, and parts and accessories therefor, namely,
interferometers and cameras, for analyzing, diagnosing, and
monitoring eye disease, namely, dry eye and meibomian gland
dysfunction; medical imaging apparatuses and devices
comprising optical lens, camera, lamp, LED, spectrometer,
used for analyzing, diagnosing, and monitoring eye disease,
namely, dry eye and meibomian gland dysfunction; electronic
medical temperature controller, and parts and accessories
therefor, used primarily for temperature controller
purposes, namely, for delivering and controlling heat to
meibomian glands for use in treating eye disease, namely,
dry eye and meibomian gland dysfunction; electronic medical
pressure controller, and parts and accessories therefor,
used primarily for controlling pressure, namely, for
applying and controlling pressure to the meibomian glands
for use in treating eye disease, namely, dry eye and
meibomian gland dysfunction; electronic medical fluid
transfer controller, and parts and accessories therefor,
used primarily for controlling and transferring heated fluid
to the eye for use in treating eye disease, namely, dry eye
and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories
therefor, used for analyzing, diagnosing, treating, and
monitoring eye disease, namely, dry eye and meibomian gland
dysfunction; medical devices, and parts and accessories
therefor, for expressing obstructions or occlusions from
meibomian glands; medical heater used primarily for medical
purposes, namely, for applying heat to a patient's eye and
related eye structure for treating eye diseases, namely, dry
eye and meibomian gland dysfunction; medical devices,
namely, medical contact lens used primarily for medical
purposes containing an electrical heating element for
applying heat to meibomian glands when installed on a
patient's eye for treating dry eye and meibomian gland
dysfunction. Printed instructional, educational and teaching materials in
the field of eye disease, namely, dry eye and meibomian
gland dysfunction; printed instructional, educational and
teaching materials for analysis, diagnosis, treatment, and
monitoring of eye disease, namely, dry eye and meibomian
gland dysfunction. Education services, namely, classes, conferences, seminars,
workshops, in the field of eye disease, namely, dry eye and
meibomian gland dysfunction; education services, namely,
providing seminars, tutorials, workshops for analyzing,
diagnosing, treating, and monitoring eye disease, namely,
dry eye and meibomian gland dysfunction; training services
in the field of eye disease, namely, dry eye and meibomian
gland dysfunction; training services, namely, providing
seminars, tutorials, workshops for analyzing, diagnosing,
treating, and monitoring eye disease, namely, dry eye and
meibomian gland dysfunction. Medical services, namely, providing medical analysis,
diagnosis, treatment, and monitoring of eye diseases and
conditions; medical services, namely, providing medical
analysis, diagnosis, treatment, and monitoring of dry eye
and meibomian gland dysfunction; providing medical
information related to eye disease, namely, dry eye and
meibomian gland dysfunction, for educational purposes.
66.
METHODS, SYSTEMS, AND APPARATUSES FOR HEAT TREATMENT FOR TREATING MEIBOMIAN GLAND DYSFUNCTION
Apparatuses, systems, and methods of treating meibomian gland dysfunction. Heat is applied to the patient's eyelid or surrounding tissue to apply heat to the patient's meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the patient's eyelid or surrounding tissue to improve conductive heat transfer and reduce blood flow in the tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reached desired temperature levels and/or aid in reducing discomfort to the patient during treatment.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Ophthalmic solutions, drops, and gels used for the treatment of ocular disorders, namely dry eye and meibomian gland dysfunction.
(2) Computer hardware and software, and parts therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction.
(3) Medical devices and parts therefor used for analyzing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for diagnosing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Camera-based imaging devices and parts therefor, used for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Temperature controller, and parts therefor, for delivering heat and controlling temperature of heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Pressure controller, and parts therefor, for applying pressure and controlling pressure applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Heating element for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; Medical device, and parts therefor, for expressing obstructions or occlusions from meibomian glands; Medical temperature controller, and parts therefor, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical pressure controller, and parts therefor, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical heater for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Medical lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction.
(4) Printed instructional, educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional , educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely dry eye and meibomian gland dysfunction. (1) Education information for eye disease, namely dry eye and meibomian gland dysfunction; Education services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Education services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Training services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Training services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction.
(2) Analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Ophthalmic solutions, drops, and gels used for the treatment of ocular disorders, namely dry eye and meibomian gland dysfunction.
(2) Computer hardware and software, and parts therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction.
(3) Medical devices and parts therefor used for analyzing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for diagnosing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Camera-based imaging devices and parts therefor, used for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Temperature controller, and parts therefor, for delivering heat and controlling temperature of heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Pressure controller, and parts therefor, for applying pressure and controlling pressure applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Heating element for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; Medical device, and parts therefor, for expressing obstructions or occlusions from meibomian glands; Medical temperature controller, and parts therefor, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical pressure controller, and parts therefor, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical heater for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Medical lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction.
(4) Printed instructional, educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely dry eye and meibomian gland dysfunction. (1) Education information for eye disease, namely dry eye and meibomian gland dysfunction; Education services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Education services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Training services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Training services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction.
(2) Analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction.
In one embodiment consistent with the present invention a method of treating mammalian meibomian glands (10) involves clearing the glands by applying a regulated heat (104) to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state and maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated to express fluid from the glands (108), wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) (112) can then be used to assist in maintaining proper flow of lipids from the glands. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Computer hardware and software, and parts and accessories therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices in the nature of a system comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction sold as a unit Printed [ instructional, ] educational [ and teaching ] materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction [ Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; ] Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes
71.
Inner eyelid treatment for treating meibomian gland dysfunction
A method of treating meibomian gland dysfunction. Heat is applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
A method of treating meibomian gland dysfunction. Heat is applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the inside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
A method of treating meibomian gland dysfunction. Heat is applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the tissue proximate the patient's meibomian glands to improve conductive heat transfer and reduce blood flow in the tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reached desired temperature levels and/or aid in reducing discomfort to the patient during treatment.
A system for treating meibomian gland dysfunction. A controller controls a lid warmer attached onto a patient's eye to generate heat on the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. An eyecup may be employed to generate a force on the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
A61F 7/12 - Devices for heating or cooling internal body cavities
A61H 7/00 - Devices for suction-kneading massageDevices for massaging the skin by rubbing or brushing not otherwise provided for
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61H 15/00 - Massage by means of rollers, balls, e.g. inflatable, chains, or roller chains
A system for treating meibomian gland dysfunction. A controller controls heat applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force is also applied to tissue proximate the patient's meibomian glands during the application of heat to improve conductive heat transfer and reduce blood flow in tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands. Reducing the amount of time to reached desired temperature levels an aid in reducing discomfort to the patient during treatment.
A system for treating meibomian gland dysfunction. A controller controls heat applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the inside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.
A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
A61H 7/00 - Devices for suction-kneading massageDevices for massaging the skin by rubbing or brushing not otherwise provided for
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
A61H 15/00 - Massage by means of rollers, balls, e.g. inflatable, chains, or roller chains
An apparatus for testing meibomian glands in the eyelids of humans for meibomian gland disease is provided The apparatus comp꧀ses a handle, and a probe tip mounted for movement relative to said handle such that when the probe tip is placed against the eyelid and compressive force is applied, movement of the handle a preselected distance replicates the force required for natural expression of secretion from the meibomian gland An indicator means selected from the group consisting of auditory, visual and tactile signals is provided and when activated alerts the clinician that the required force has been reached According to the method of the present invention a probe tip is located in contacting relation with the eyelid, the probe tip being connected to a handle (105) When pressure is exerted on the eyelid by pressing it against the eyelid, a preselected pressure is exerted thereon
A61B 3/16 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring intraocular pressure, e.g. tonometers
In an illustrative embodiment, an apparatus for imaging a portion of a mammalian eyelid has an eye contact lenspiece configured to direct the light through an eyelid from posterior to anterior surface to thereby trans-illuminate the eyelid, when the light source illuminates the contact lens. An imaging device receives an image of the eyelid as it is trans-illuminated. Other methods and apparatus are presented in various embodiments, hence this abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland (20) in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland (20). This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
Consistent with certain embodiments, an apparatus provides regulated heat to at least one of a patient's eyelids, using a heater unit (38) having a heating element (42) that produces heat that is transferred to the patient's eyelid when an electrical signal is applied thereto. A temperature regulator applies an electrical signal to the heating elements (42) in order to achieve heating of the heating elements (42) to a specified temperature range. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice (O). The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is applied to the exterior surface of the eyelid, proximate to the gland channel orifice (O), a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed.
B08B 3/10 - Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
84.
METHOD AND APPARATUS FOR TREATING GLAND DYSFUNCTION
A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice. The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is it is applied to the exterior surface of the eyelid, proximate to the gland channel orifice, a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed. In an exemplary embodiment, the medium is water heated to a temperature of between about 42° C. and about 46° C. Depending on the particular type and composition of the obstruction, the fluid jet operates to melt or soften the obstruction and to milkingly move the corpus of the softened obstruction up the gland channel from the end opposite the meibomian gland orifice and out of the gland orifice. Repeated application of the heated fluid jet may also be necessary to soften and/or express the obstruction.
In accordance with certain illustrative embodiments, methods and apparatuses of treating obstructive disorders of the structure of an eye or eyelid are disclosed. The treating may involve applying heat to the structure containing the obstructive disorder to melt an obstruction in the structure and place the obstruction in a melted state. The heat may be maintained for a time period to melt the obstruction and place the obstruction in the melted state. The structure may be treated by expressing the melted obstruction from the structure. The treating may be carried out either during the time period or after the time period when heat is applied but while the obstruction is in the melted state. In certain embodiments, the method further involves subsequently treating the structure by use of a pharmacological agent. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction Medical apparatuses and devices, and parts and accessories therefor, used for analyzing [, diagnosing, treating, ] and monitoring eye disease, namely, dry eye and meibomian gland dysfunction;[ Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; ] Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction [ ; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction ] [ Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction ] [ Education services, namely, classes, conferences, seminars, workshops, in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Training services in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction ] [ Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; ] Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes
16 - Paper, cardboard and goods made from these materials
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical apparatuses and devices, and parts and accessories therefor, used for [ analyzing, diagnosing, ] treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction [ Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction ] [ Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; ] Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes
In one embodiment consistent with the present invention a method of treating mammalian meibomian glands involves clearing the glands by applying a regulated heat to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state and maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated to express fluid from the glands, wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) can then be used to assist in maintaining proper flow of lipids from the glands. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
A61B 18/04 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
