TearScience, Inc.

États‑Unis d’Amérique

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Type PI
        Brevet 84
        Marque 13
Juridiction
        États-Unis 65
        International 26
        Canada 4
        Europe 2
Date
2022 2
Avant 2021 95
Classe IPC
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient 36
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil 28
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux 22
A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain 21
G06T 7/00 - Analyse d'image 15
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Classe NICE
10 - Appareils et instruments médicaux 13
09 - Appareils et instruments scientifiques et électriques 12
16 - Papier, carton et produits en ces matières 12
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture. 12
41 - Éducation, divertissements, activités sportives et culturelles 10
Voir plus

1.

Ocular surface interferometry (OSI) for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 17573899
Numéro de brevet 11771317
Statut Délivré - en vigueur
Date de dépôt 2022-01-12
Date de la première publication 2022-05-05
Date d'octroi 2023-10-03
Propriétaire Tearscience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image

2.

Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis

      
Numéro d'application 17498102
Numéro de brevet 11844586
Statut Délivré - en vigueur
Date de dépôt 2021-10-11
Date de la première publication 2022-01-27
Date d'octroi 2023-12-19
Propriétaire Tearscience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Grenon, Joshua
  • Liddle, Scott
  • Bacich, Steve
  • Jans, John M.

Abrégé

Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured, showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray-like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

Classes IPC  ?

  • A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

3.

TEARSCIENCE

      
Numéro d'application 018336172
Statut Enregistrée
Date de dépôt 2020-11-11
Date d'enregistrement 2021-05-11
Propriétaire TearScience, Inc (USA)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating clement for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices in the nature of a system comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction sold as a unit. Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.

4.

Ocular surface interferometry (OSI) for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 16782384
Numéro de brevet 11259700
Statut Délivré - en vigueur
Date de dépôt 2020-02-05
Date de la première publication 2020-06-04
Date d'octroi 2022-03-01
Propriétaire TearScience Inc (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image

5.

Methods and apparatuses for treating gland dysfunction

      
Numéro d'application 16375196
Numéro de brevet 10905898
Statut Délivré - en vigueur
Date de dépôt 2019-04-04
Date de la première publication 2019-07-25
Date d'octroi 2021-02-02
Propriétaire Tearscience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.

Abrégé

A method of treating dry eye includes delivering light energy from outside an eyelid toward the eyelid, and maintaining the delivery of the light energy toward the eyelid for a period of time to soften an obstruction of at least one meibomian gland. The light energy may be delivered specifically to the obstruction in the at least one meibomian gland without physically contacting the at least one meibomian gland, or the light energy delivered toward the eyelid may conductively apply heat to the meibomian gland to melt the obstruction. A corresponding apparatus includes a light energy source positionable outside an eyelid and configured to deliver the light energy from outside an eyelid toward the eyelid, and a controller configured to control the light energy source to maintain the delivery of the light energy toward the eyelid for a period of time to soften the obstruction.

Classes IPC  ?

  • A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61N 1/40 - Application de champs électriques par couplage inductif ou capacitif
  • A61N 5/02 - Thérapie par radiations utilisant des hyperfréquences
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons
  • A61N 5/067 - Thérapie par radiations utilisant un rayonnement lumineux utilisant un rayonnement laser

6.

Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis

      
Numéro d'application 16355039
Numéro de brevet 11141065
Statut Délivré - en vigueur
Date de dépôt 2019-03-15
Date de la première publication 2019-07-11
Date d'octroi 2021-10-12
Propriétaire TearScience, Inc (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Grenon, Joshua
  • Liddle, Scott
  • Bacich, Steve
  • Jans, John M.

Abrégé

Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

Classes IPC  ?

  • A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

7.

Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography

      
Numéro d'application 16251332
Numéro de brevet 10582849
Statut Délivré - en vigueur
Date de dépôt 2019-01-18
Date de la première publication 2019-05-23
Date d'octroi 2020-03-10
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/107 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
  • G02B 26/02 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander l'intensité de la lumière

8.

Melting meibomian gland obstructions

      
Numéro d'application 16172159
Numéro de brevet 10940074
Statut Délivré - en vigueur
Date de dépôt 2018-10-26
Date de la première publication 2019-02-28
Date d'octroi 2021-03-09
Propriétaire TearScience Inc (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Barrier, Omer Jack
  • Foshee, David
  • Korb, Donald R.
  • Willis, Timothy R.

Abrégé

An apparatus providing heat for treatment of an eyelid includes a heater unit configured to apply heat directly to an outer surface of the eyelid when an electrical signal is applied to the heater unit. The heater unit is affixed directly to the outer surface of the eyelid using an adhesive. A temperature regulator applies the electrical signal to the heater unit in order to achieve heating of the outer surface of the eyelid to a specified temperature range. A method is also disclosed that comprises affixing a heater unit directly into contact with the outer surface of the eyelid using an the adhesive. A control signal is applied to the heater unit to generate heat to the outer surface of the eyelid and is maintained for a period of time until the outer surface of the eyelid is heated to a specified temperature range.

Classes IPC  ?

  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons

9.

Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 16008619
Numéro de brevet 10582848
Statut Délivré - en vigueur
Date de dépôt 2018-06-14
Date de la première publication 2018-10-18
Date d'octroi 2020-03-10
Propriétaire Tearscience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image

10.

Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography

      
Numéro d'application 15995612
Numéro de brevet 10244939
Statut Délivré - en vigueur
Date de dépôt 2018-06-01
Date de la première publication 2018-10-04
Date d'octroi 2019-04-02
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/107 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
  • G02B 26/02 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander l'intensité de la lumière

11.

Ocular tear film peak detection and stabilization detection systems and methods for determining tear film layer characteristics

      
Numéro d'application 15791615
Numéro de brevet 10512396
Statut Délivré - en vigueur
Date de dépôt 2017-10-24
Date de la première publication 2018-02-15
Date d'octroi 2019-12-24
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Liddle, Scott
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.

Classes IPC  ?

  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • G06T 7/00 - Analyse d'image
  • G01B 11/06 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur pour mesurer l'épaisseur

12.

LIPISCAN

      
Numéro d'application 017447269
Statut Enregistrée
Date de dépôt 2017-11-08
Date d'enregistrement 2018-04-17
Propriétaire TearScience, Inc (USA)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles

Produits et services

Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Printed instructional, educational and teaching materials in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction.

13.

Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 15608308
Numéro de brevet 10004396
Statut Délivré - en vigueur
Date de dépôt 2017-05-30
Date de la première publication 2017-09-21
Date d'octroi 2018-06-26
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image

14.

Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography

      
Numéro d'application 15615244
Numéro de brevet 09993151
Statut Délivré - en vigueur
Date de dépôt 2017-06-06
Date de la première publication 2017-09-21
Date d'octroi 2018-06-12
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G02B 26/02 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander l'intensité de la lumière
  • A61B 3/107 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée

15.

Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on dry eye tear film characteristic analysis and dry eye symptoms

      
Numéro d'application 14268647
Numéro de brevet 09888839
Statut Délivré - en vigueur
Date de dépôt 2014-05-02
Date de la première publication 2017-08-31
Date d'octroi 2018-02-13
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Bacich, Steve

Abrégé

Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • G06T 7/00 - Analyse d'image

16.

Background reduction apparatuses and methods of ocular surface interferometry (OSI) employing polarization for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 15589146
Numéro de brevet 09999346
Statut Délivré - en vigueur
Date de dépôt 2017-05-08
Date de la première publication 2017-08-24
Date d'octroi 2018-06-19
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Background reduction apparatuses and methods of Ocular Surface Interferometry (OSI) employing polarization are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT) and can be used to evaluate and potentially diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in at least one image. The at least one image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • G06T 7/00 - Analyse d'image

17.

Apparatuses and methods for determining tear film break-up time and/or for detecting lid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms

      
Numéro d'application 15365267
Numéro de brevet 10413174
Statut Délivré - en vigueur
Date de dépôt 2016-11-30
Date de la première publication 2017-03-23
Date d'octroi 2019-09-17
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Blackie, Caroline
  • Willis, Timothy R.
  • Bacich, Steve

Abrégé

Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image
  • G06T 7/11 - Découpage basé sur les zones
  • G06T 7/90 - Détermination de caractéristiques de couleur
  • G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
  • G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
  • G06K 9/78 - Combinaison de l'obtention de l'image et de fonctions de reconnaissance

18.

Methods and apparatuses for treatment of meibomian gland dysfunction

      
Numéro d'application 15359856
Numéro de brevet 10952896
Statut Délivré - en vigueur
Date de dépôt 2016-11-23
Date de la première publication 2017-03-16
Date d'octroi 2021-03-23
Propriétaire TearScience Inc (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Jans, John Martin
  • Hutchinson, Jordan W.
  • Gausmann, Keith
  • Korb, Donald R.

Abrégé

Apparatus and methods for treating dry eye include an energy source configured to apply energy to an obstruction located in a meibomian gland of a patient's eyelid. The apparatus also comprises an insulator configured to be positioned between a rear portion of the patient's eyelid and a surface of the patient's eyeball. An inner surface of the insulator has a curvature greater than that of the patient's eyeball such that an air pocket is formed between the inner surface of the insulator and the patient's eyeball, wherein the air pocket provides additional insulation to reduce or eliminate an amount of heat due to the applied energy from the energy source from being conducted to the surface of the patient's eyeball, such that the applied energy does not cause the temperature to reach a temperature sufficient to cause damage to a corneal or scleral portion of the patient's eyeball.

Classes IPC  ?

  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61F 7/12 - Dispositifs pour chauffer ou refroidir les cavités internes du corps
  • A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
  • A61N 7/00 - Thérapie par ultrasons
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61B 18/08 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage à l'aide de sondes chauffées électriquement

19.

LIPISCAN

      
Numéro d'application 1322822
Statut Enregistrée
Date de dépôt 2016-08-18
Date d'enregistrement 2016-08-18
Propriétaire TearScience, Inc. (USA)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Printed instructional, educational and teaching materials in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; printed instructional, educational and teaching materials for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Education services, namely, classes, conferences, seminars, workshops, in the field of meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction. Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye diseases and conditions; medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; providing medical information related to meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.

20.

Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography

      
Numéro d'application 15152624
Numéro de brevet 09668647
Statut Délivré - en vigueur
Date de dépôt 2016-05-12
Date de la première publication 2016-09-01
Date d'octroi 2017-06-06
Propriétaire TearScience Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/107 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
  • G02B 26/02 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander l'intensité de la lumière

21.

Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 15143834
Numéro de brevet 09662008
Statut Délivré - en vigueur
Date de dépôt 2016-05-02
Date de la première publication 2016-08-25
Date d'octroi 2017-05-30
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image

22.

LIPISCAN

      
Numéro d'application 179658900
Statut Enregistrée
Date de dépôt 2016-08-19
Date d'enregistrement 2019-08-07
Propriétaire TearScience, Inc. (USA)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

(1) Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction (2) Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction (3) Printed instructional, educational and teaching materials namely, guides, manuals and pamphlets in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials namely, guides, manuals and pamphlets for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction (1) Education services, namely, classes, conferences, seminars, workshops, in the field of meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction (2) Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Providing medical information related to meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes

23.

LIPISCAN

      
Numéro de série 86923210
Statut Enregistrée
Date de dépôt 2016-02-29
Date d'enregistrement 2018-01-23
Propriétaire TearScience, Inc. ()
Classes de Nice  ?
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières

Produits et services

[ Education services, namely, classes, conferences, seminars, workshops, in the field of meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibography, meibomian gland imaging, and eye disease, namely, dry eye and meibomian gland dysfunction; Training services in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction ] [ Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Providing medical information related to meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes ] Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction Printed instructional, educational and teaching materials in the field of meibography, meibomian gland imaging and eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, and monitoring of meibomian glands and eye disease, namely, dry eye and meibomian gland dysfunction

24.

Ocular tear film peak detection and stabilization detection systems and methods for determining tear film layer characteristics

      
Numéro d'application 14543583
Numéro de brevet 09795290
Statut Délivré - en vigueur
Date de dépôt 2014-11-17
Date de la première publication 2015-05-21
Date d'octroi 2017-10-24
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Liddle, Scott
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G01B 11/06 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur pour mesurer l'épaisseur
  • G06T 7/00 - Analyse d'image

25.

APPARATUSES AND METHODS FOR DETECTING LID MARGIN CONTACT AND BLINK RATES, PARTICULARLY FOR DIAGNOSING, MEASURING, AND/OR ANALYZING DRY EYE CONDITIONS AND SYMPTOMS

      
Numéro d'application US2014065441
Numéro de publication 2015/073664
Statut Délivré - en vigueur
Date de dépôt 2014-11-13
Date de publication 2015-05-21
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Grenon, Stephen, M.
  • Blackie, Caroline
  • Willis, Timothy, R.
  • Bacich, Steve

Abrégé

Embodiments disclosed herein include devices, systems, and methods for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during blink rate related procedures.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil

26.

Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography

      
Numéro d'application 14543931
Numéro de brevet 09339177
Statut Délivré - en vigueur
Date de dépôt 2014-11-18
Date de la première publication 2015-05-21
Date d'octroi 2016-05-17
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux

27.

OCULAR TEAR FILM PEAK DETECTION AND STABILITZATION DETECTION SYSTEMS AND METHODS FOR DETERMINING TEAR FILM LAYER CHARACTERISTICS

      
Numéro d'application US2014065992
Numéro de publication 2015/073986
Statut Délivré - en vigueur
Date de dépôt 2014-11-17
Date de publication 2015-05-21
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Liddle, Scott
  • Korb, Donald, R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

28.

Methods and apparatuses for treatment of meibomian glands

      
Numéro d'application 14510863
Numéro de brevet 10376273
Statut Délivré - en vigueur
Date de dépôt 2014-10-09
Date de la première publication 2015-04-09
Date d'octroi 2019-08-13
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Grenon, Stephen M.

Abrégé

Methods and apparatuses of treating meibomian glands are disclosed. The method comprises applying regulated heat to an eyelid to reach a temperature adequate to melt at least one obstruction within at least one meibomian gland. The method also comprises maintaining the regulated heat for a time period adequate to place the at least obstruction in the melted state. The method further comprises positioning a pressure application device into contact with the patient's eyelid and applying a pressure with the pressure application device over a substantial portion of the eyelid to express the at least one obstruction from the meibomian gland. An apparatus suitable to treat meibomian glands comprises a heater, a controller, and a pressure applicator configured to be placed into contact with the eyelid and apply a pressure over a substantial portion of the eyelid to express the at least one obstruction from the meibomian gland.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61N 7/00 - Thérapie par ultrasons
  • A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux

29.

Eyelid illumination systems and method for imaging meibomian glands for meibomian gland analysis

      
Numéro d'application 14269646
Numéro de brevet 10278587
Statut Délivré - en vigueur
Date de dépôt 2014-05-05
Date de la première publication 2014-11-06
Date d'octroi 2019-05-07
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Grenon, Joshua
  • Liddle, Scott
  • Bacich, Steve
  • Jans, John M.

Abrégé

Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

Classes IPC  ?

  • A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus

30.

METHODS AND APPARATUSES FOR DETERMNING CONTACT LENS INTOLERANCE IN CONTACT LENS WEARER PATIENTS BASED ON DRY EYE TEAR FILM CHARACTERISTIC ANALYSIS AND DRY EYE SYMPTOMS

      
Numéro d'application US2014036636
Numéro de publication 2014/179728
Statut Délivré - en vigueur
Date de dépôt 2014-05-02
Date de publication 2014-11-06
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Grenon, Stephen, M.
  • Bacich, Steven, R.

Abrégé

Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

31.

EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS

      
Numéro d'application US2014036780
Numéro de publication 2014/179795
Statut Délivré - en vigueur
Date de dépôt 2014-05-05
Date de publication 2014-11-06
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Korb, Donald, R.
  • Grenon, Joshua
  • Liddle, Scott
  • Bacich, Steve

Abrégé

Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

32.

Ocular surface interferometry (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 14299504
Numéro de brevet 09693682
Statut Délivré - en vigueur
Date de dépôt 2014-06-09
Date de la première publication 2014-09-25
Date d'octroi 2017-07-04
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image

33.

FULL-EYE ILLUMINATION OCULAR SURFACE IMAGING OF AN OCULAR TEAR FILM FOR DETERMINING TEAR FILM THICKNESS AND/OR PROVIDING OCULAR TOPOGRAPHY

      
Numéro d'application US2013077117
Numéro de publication 2014/100678
Statut Délivré - en vigueur
Date de dépôt 2013-12-20
Date de publication 2014-06-26
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Korb, Donald, R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • G01B 11/25 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer des contours ou des courbes en projetant un motif, p. ex. des franges de moiré, sur l'objet

34.

Full-eye illumination ocular surface imaging of an ocular tear film for determining tear film thickness and/or providing ocular topography

      
Numéro d'application 14137105
Numéro de brevet 08888286
Statut Délivré - en vigueur
Date de dépôt 2013-12-20
Date de la première publication 2014-04-17
Date d'octroi 2014-11-18
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/107 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
  • G06T 7/00 - Analyse d'image

35.

Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma

      
Numéro d'application 14074123
Numéro de brevet 09913678
Statut Délivré - en vigueur
Date de dépôt 2013-11-07
Date de la première publication 2014-03-06
Date d'octroi 2018-03-13
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Friedland, Beth
  • Korb, Donald R.
  • Grenon, Steve
  • Jans, John
  • Gausmann, Keith
  • Willis, Timothy R.

Abrégé

Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (IOP) in a patient to either prevent or treat open-angle glaucoma. Heat is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT). By loosening or relaxing clogs or other inhibitors in the trabecular meshwork, the outflow path for aqueous humor is increased or restored, which can lower IOP and either prevent or treat glaucoma. Force may also be applied to the patient's eye to apply pressure to the trabecular meshwork to further assist in the loosening or relaxing of clogs or other inhibitors in the trabecular meshwork.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61H 1/00 - Appareils pour l'exercice passifAppareils vibrateursDispositifs de chiropractie, p. ex. dispositifs pour appliquer des chocs au corps, dispositifs externes pour étirer ou aligner de façon brève des os non fracturés
  • A61B 18/10 - Sources d'énergie pour ces sondes
  • A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
  • A61N 7/00 - Thérapie par ultrasons

36.

DIAGNOSING AND TREATING LIPID TRANSPORT DEFICIENCY IN OCULAR TEAR FILMS

      
Numéro d'application US2013056199
Numéro de publication 2014/031857
Statut Délivré - en vigueur
Date de dépôt 2013-08-22
Date de publication 2014-02-27
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Bacich, Steven, R.
  • Blackie, Caroline
  • Grenon, Stephen, M.

Abrégé

Methods and apparatuses are disclosed for the diagnosis and removal of the devitalized and/or dead cell material formed in the lid margin to attempt to restore a normal lid margin. In this manner, the devitalized and/or dead cell material are removed or the amount present is reduced or no longer present to prevent, reduce, or affect the transport of lipid secreted by the meibomian glands to the tear film to reduce evaporative dry eye and improve dry eye conditions in patients. The diagnosis and removal of devitalized and/or dead cell material may be performed at desired intervals. Patients that suffer from conditions that block meibomian gland orifices, partial, infrequent, or inhibited blinking resulting in reduced lipid secretions from meibomian glands, and/or blockages in meibomian gland channels reducing secretion of lipids through the meibomian gland orifices may require more frequent diagnosis and treatment to remove devitalized and/or dead cell material.

Classes IPC  ?

  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil

37.

Apparatuses and methods for determining tear film break-up time and/or for detecting lid margin contact and blink rates, particulary for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms

      
Numéro d'application 13887429
Numéro de brevet 09545197
Statut Délivré - en vigueur
Date de dépôt 2013-05-06
Date de la première publication 2014-01-16
Date d'octroi 2017-01-17
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Blackie, Caroline
  • Willis, Timothy R.
  • Bacich, Steve

Abrégé

Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • G06T 7/00 - Analyse d'image

38.

Apparatuses and methods of ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 13870054
Numéro de brevet 08915592
Statut Délivré - en vigueur
Date de dépôt 2013-04-25
Date de la première publication 2013-11-21
Date d'octroi 2014-12-23
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Apparatuses and methods employing ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film are disclosed. The apparatuses and methods can be employed for measuring tear film layer thickness (TFLT) of the ocular tear film, which includes lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). An imaging device is focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device is focused on the lipid layer of the tear film to capture a second image containing background signal(s) in the first image. The second image can be subtracted from the first image to reduce and/or eliminate background signal(s) in the first image to produce a resulting image that can be analyzed to measure tear film layer thickness (TFLT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • G06T 7/00 - Analyse d'image
  • G01B 11/06 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur pour mesurer l'épaisseur
  • G06T 5/00 - Amélioration ou restauration d'image
  • G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction

39.

OPTICAL PHANTOMS FOR USE WITH OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES AND SYSTEMS CONFIGURED TO MEASURE TEAR FILM LAYER THICKNESS(ES), AND RELATED USES FOR CALIBRATION

      
Numéro d'application US2013039395
Numéro de publication 2013/166352
Statut Délivré - en vigueur
Date de dépôt 2013-05-03
Date de publication 2013-11-07
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Korb, Donald, R.
  • Weber, William, L.
  • Liddle, Scott

Abrégé

Embodiments of the detailed description include optical phantoms for use with ocular surface interferometery (OSI) devices and systems configured to measure tear film layer thickness(es), and related use for calibration. The ocular surface interferometry (OSI) devices, systems, and methods can be used for imaging an ocular tear film and/or measuring a tear film layer thickness (TFLT) in a patient's ocular tear film. The OSI devices, systems, and methods can be used to measure the thickness of the lipid layer component (LLT) and/or the aqueous layer component (ALT) of the ocular tear film. "TFLT" as used herein includes LLT, ALT, or both LLT and ALT. "Measuring TFLT" as used herein includes measuring LLT, ALT, or both LLT and ALT. Imaging the ocular tear film and measuring TFLT can be used in the diagnosis of a patient's tear film, including but not limited to lipid layer and aqueous layer deficiencies.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil

40.

APPARATUSES AND METHODS FOR DETERMINING TEAR FILM BREAK-UP TIME AND/OR FOR DETECTING LID MARGIN CONTACT AND BLINK RATES, PARTICULARLY FOR DIAGNOSING, MEASURING, AND/OR ANALYZING DRY EYE CONDITIONS AND SYMPTOMS

      
Numéro d'application US2013039617
Numéro de publication 2013/166477
Statut Délivré - en vigueur
Date de dépôt 2013-05-06
Date de publication 2013-11-07
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Grenon, Stephen, M.
  • Blackie, Caroline
  • Willis, Timothy, R.
  • Bacich, Steve

Abrégé

Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.

Classes IPC  ?

41.

BACKGROUND REDUCTION APPARATUSES AND METHODS OF OCULAR SURFACE INTERFEROMETRY (OSI) EMPLOYING POLARIZATION FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM

      
Numéro d'application US2013038149
Numéro de publication 2013/163383
Statut Délivré - en vigueur
Date de dépôt 2013-04-25
Date de publication 2013-10-31
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Background reduction apparatuses and methods of Ocular surface interferometry (OSI) employing polarization are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT) and can be used to evaluate and potentially diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in at least one image. The at least one image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • G01B 11/06 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur pour mesurer l'épaisseur

42.

APPARATUSES AND METHODS OF OCULAR SURFACE INTERFEROMETRY (OSI) EMPLOYING POLARIZATION AND SUBTRACTION FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM

      
Numéro d'application US2013038116
Numéro de publication 2013/163367
Statut Délivré - en vigueur
Date de dépôt 2013-04-25
Date de publication 2013-10-31
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Weber, William, L.
  • Chinnock, Randal, B.
  • Gravely, Benjamin, T.
  • Grenon, Stephen, M.

Abrégé

Apparatuses and methods employing ocular surface interferometry (OSI) employing polarization and subtraction for imaging, processing, and/or displaying an ocular tear film are disclosed. The apparatuses and methods can be employed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil

43.

Background reduction apparatuses and methods of ocular surface interferometry (OSI) employing polarization for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 13870214
Numéro de brevet 09642520
Statut Délivré - en vigueur
Date de dépôt 2013-04-25
Date de la première publication 2013-09-05
Date d'octroi 2017-05-09
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Background reduction apparatuses and methods of Ocular surface interferometry (OSI) employing polarization are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT) and can be used to evaluate and potentially diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in at least one image. The at least one image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • G06T 7/00 - Analyse d'image

44.

Methods and systems for treating meibomian gland dysfunction using radio-frequency energy

      
Numéro d'application 13590828
Numéro de brevet 09719977
Statut Délivré - en vigueur
Date de dépôt 2012-08-21
Date de la première publication 2013-02-28
Date d'octroi 2017-08-01
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Gravely, Benjamin Tyson
  • Bacich, Steven

Abrégé

A method of treating meibomian gland dysfunction is disclosed. The method includes directing RF energy to an internal portion of a meibomian gland, selectively targeting an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction, and expressing the obstruction from the duct of the meibomian gland. An apparatus for treating meibomian gland dysfunction is also disclosed. The apparatus comprises at least one RF electrode configured to direct RF energy to an internal portion of a meibomian gland located in an eyelid of an eye, the at least one RF electrode further configured to selectively target an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction. The apparatus also comprises at least one expressor configured to express the obstruction from the duct of the meibomian gland.

Classes IPC  ?

  • A61F 7/08 - Bassinoires, coussinets ou tapis chauffantsBouillottes
  • A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
  • G01N 33/22 - CombustiblesExplosifs
  • A61N 1/40 - Application de champs électriques par couplage inductif ou capacitif
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61H 9/00 - Massages pneumatiques ou hydrauliques
  • A61H 23/02 - Massage par percussion ou vibration, p. ex. en utilisant une vibration ultrasoniqueMassage par succion-vibrationMassage avec des membranes mobiles à entraînement électrique ou magnétique
  • A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 39/08 - Dispositifs pour placer des aiguilles auxdits endroits, c.-à-d. pour l'acupuncture
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons

45.

METHODS AND SYSTEMS FOR TREATING MEIBOMIAN GLAND DYSFUNCTION USING RADIO-FREQUENCY ENERGY

      
Numéro d'application US2012044650
Numéro de publication 2013/003594
Statut Délivré - en vigueur
Date de dépôt 2012-06-28
Date de publication 2013-01-03
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Grenon, Stephen, M.
  • Willis, Timothy, R.
  • Gravely, Benjamin, Tyson
  • Bacich, Steven

Abrégé

A method of treating meibomian gland dysfunction is disclosed. The method includes directing RF energy to an internal portion of a meibomian gland, selectively targeting an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction, and expressing the obstruction from the duct of the meibomian gland. An apparatus for treating meibomian gland dysfunction is also disclosed. The apparatus comprises at least one RF electrode configured to direct RF energy to an internal portion of a meibomian gland located in an eyelid of an eye, the at least one RF electrode further configured to selectively target an obstruction within a duct of the meibomian gland with the applied RF energy to melt, loosen, or soften the obstruction. The apparatus also comprises at least one expressor configured to express the obstruction from the duct of the meibomian gland.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain

46.

Methods for diagnosing meibomian gland dysfunction

      
Numéro d'application 13271768
Numéro de brevet 08956311
Statut Délivré - en vigueur
Date de dépôt 2011-10-12
Date de la première publication 2012-10-18
Date d'octroi 2015-02-17
Propriétaire TearSciecne, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Blackie, Caroline
  • Stevens, Christy

Abrégé

Methods of diagnosing meibomian gland dysfunction are disclosed. The methods may be standardized and provide an accurate diagnosis of whether meibomian gland dysfunction exists. In one embodiment, a method is provided that utilizes an evaluation tool to apply a force for a preselected period of time to at least one of a plurality of meibomian glands in two or more regions of a plurality of regions of an eyelid. A grade is assigned to the at least one meibomian gland of the plurality of meibomian glands in each of the two or more regions based on any secretion that is expressed from each meibomian gland. In this manner, a plurality of meibomian gland secretion grades is obtained. The plurality of meibomian gland secretion grades is indicative of the presence of meibomian gland dysfunction.

Classes IPC  ?

  • A61B 5/103 - Dispositifs de mesure pour le contrôle de la forme, du dessin, de la dimension ou du mouvement du corps ou de parties de celui-ci, à des fins de diagnostic
  • A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

47.

Tear film measurement

      
Numéro d'application 13455628
Numéro de brevet 08585204
Statut Délivré - en vigueur
Date de dépôt 2012-04-25
Date de la première publication 2012-09-20
Date d'octroi 2013-11-19
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Gravely, Benjamin T.
  • Korb, Donald R.

Abrégé

A method for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye. Light is directed to the lipid layer of a patient's eye with an illuminator that is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil

48.

Meibomian gland imaging

      
Numéro d'application 13472654
Numéro de brevet 08600484
Statut Délivré - en vigueur
Date de dépôt 2012-05-16
Date de la première publication 2012-09-06
Date d'octroi 2013-12-03
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Gravely, Benjamin T.
  • Korb, Donald R.

Abrégé

A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

49.

System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction

      
Numéro d'application 13367865
Numéro de brevet 08523928
Statut Délivré - en vigueur
Date de dépôt 2012-02-07
Date de la première publication 2012-08-02
Date d'octroi 2013-09-03
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.

Abrégé

A system for treating meibomian gland dysfunction comprising a heating element that applies heat to the inside of the eyelid to provide conductive heat transfer to the meibomian glands, which assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired higher temperature levels more quickly and efficiently when heating the inside of the eyelid, which may assist in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force application device may also apply force to the patient's eyelid to express the obstruction from the meibomian gland, including from a channel of the meibomian gland, and to increase the temperature level and/or reduce the time to reach desired temperature levels.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

50.

System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction

      
Numéro d'application 13368976
Numéro de brevet 08632578
Statut Délivré - en vigueur
Date de dépôt 2012-02-08
Date de la première publication 2012-06-07
Date d'octroi 2014-01-21
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Jans, John Martin

Abrégé

A system for treating meibomian gland dysfunction comprising a heating element that applies heat to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands, which assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force application device may also apply force to tissue proximate the patient's meibomian glands during the application of heat to improve conductive heat transfer and reduce blood flow in tissue that causes convective heat loss, and to help express obstructions from the meibomian gland, including from a channel of the meibomian gland, with reduced discomfort to the patient. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

51.

System for outer eyelid heat and pressure treatment for treating meibomian gland dysfunction

      
Numéro d'application 13367908
Numéro de brevet 08617229
Statut Délivré - en vigueur
Date de dépôt 2012-02-07
Date de la première publication 2012-05-31
Date d'octroi 2013-12-31
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Gravely, Benjamin Tyson

Abrégé

A system for treating meibomian gland dysfunction comprising a heating element that applies heat to the outside of the eyelid to provide conductive heat transfer to the meibomian glands, which assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force application device may also apply force to the patient's eyelid during the application of heat to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss, and to help express obstructions from the meibomian gland, including from a channel of the meibomian gland. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reach desired temperature levels and/or aid in reducing discomfort to the patient during treatment.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

52.

METHODS FOR DIAGNOSING MEIBOMIAN GLAND DYSFUNCTION

      
Numéro d'application US2011055971
Numéro de publication 2012/051304
Statut Délivré - en vigueur
Date de dépôt 2011-10-12
Date de publication 2012-04-19
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald
  • Blackie, Caroline
  • Stevens, Christy

Abrégé

Methods of diagnosing meibomian gland dysfunction are disclosed. The methods may be standardized and provide an accurate diagnosis of whether meibomian gland dysfunction exists. In one embodiment, a method is provided that utilizes an evaluation tool to apply a force for a preselected period of time to at least one of a plurality of meibomian glands in two or more regions of a plurality of regions of an eyelid. A grade is assigned to the at least one meibomian gland of the plurality of meibomian glands in each of the two or more regions based on any secretion that is expressed from each meibomian gland. In this manner, a plurality of meibomian gland secretion grades is obtained. The plurality of meibomian gland secretion grades is indicative of the presence of meibomian gland dysfunction.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

53.

Apparatuses for treatment of meibomian glands

      
Numéro d'application 13183901
Numéro de brevet 09216028
Statut Délivré - en vigueur
Date de dépôt 2011-07-15
Date de la première publication 2012-01-19
Date d'octroi 2015-12-22
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Grenon, Stephen M.

Abrégé

In one embodiment, an apparatus for treating mammalian meibomian glands involves clearing the meibomian glands. The apparatus comprises a heater configured to apply a regulated heat to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state, and a controller maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated by a mechanical treatment applicator to express fluid from the glands by using a compressive force, wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) can then be used to assist in maintaining proper flow of lipids from the glands. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61H 15/02 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux conçus pour appliquer simultanément un traitement par la lumière, la chaleur ou des produits pharmaceutiques
  • A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons

54.

Apparatus for treating meibomian gland dysfunction

      
Numéro d'application 13242068
Numéro de brevet 08685073
Statut Délivré - en vigueur
Date de dépôt 2011-09-23
Date de la première publication 2012-01-19
Date d'octroi 2014-04-01
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.

Abrégé

An apparatus for treating meibomian gland dysfunction caused by meibomian gland obstruction in order to restore the natural flow of secretion from the meibomian gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid

55.

Tear film measurement

      
Numéro d'application 13195353
Numéro de brevet 08591033
Statut Délivré - en vigueur
Date de dépôt 2011-08-01
Date de la première publication 2011-11-24
Date d'octroi 2013-11-26
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Gravely, Benjamin T.

Abrégé

The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer. In order to facilitate ease of measurement, the patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the patient's eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

56.

TearScience

      
Numéro d'application 153376700
Statut Enregistrée
Date de dépôt 2011-06-29
Date d'enregistrement 2013-08-28
Propriétaire Tearscience, Inc. a corporation of North Carolina (USA)
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

(1) Computer hardware and software, and parts and accessories therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices in the nature of a system comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction sold as a unit; Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction. (1) Education services, namely classes, conferences, seminars, workshops, in the field of eye disease, namely dry eye and meibomian gland dysfunction; education services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; training services in the field of eye disease, namely dry eye and meibomian gland dysfunction; training services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.

57.

Method and apparatus for treating gland dysfunction

      
Numéro d'application 13025951
Numéro de brevet 08187310
Statut Délivré - en vigueur
Date de dépôt 2011-02-11
Date de la première publication 2011-06-09
Date d'octroi 2012-05-29
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main

58.

Method and apparatus for treating gland dysfunction

      
Numéro d'application 13025990
Numéro de brevet 08187311
Statut Délivré - en vigueur
Date de dépôt 2011-02-11
Date de la première publication 2011-06-02
Date d'octroi 2012-05-29
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil

59.

Method and apparatus for treating meibomian gland dysfunction employing fluid jet

      
Numéro d'application 12887165
Numéro de brevet 08628504
Statut Délivré - en vigueur
Date de dépôt 2010-09-21
Date de la première publication 2011-01-27
Date d'octroi 2014-01-14
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Paul, Lyle
  • Roe, Steven
  • Korb, Donald R.

Abrégé

According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice. The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is it is applied to the exterior surface of the eyelid, proximate to the gland channel orifice, a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed. In an exemplary embodiment, the medium is water heated to a temperature of between about 42° C. and about 46° C. Depending on the particular type and composition of the obstruction, the fluid jet operates to melt or soften the obstruction and to milkingly move the corpus of the softened obstruction up the gland channel from the end opposite the meibomian gland orifice and out of the gland orifice. Repeated application of the heated fluid jet may also be necessary to soften and/or express the obstruction.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain

60.

Ocular surface interferometry (OSI) methods for imaging and measuring ocular tear film layer thickness(es)

      
Numéro d'application 12798326
Numéro de brevet 08092023
Statut Délivré - en vigueur
Date de dépôt 2010-04-01
Date de la première publication 2010-10-14
Date d'octroi 2012-01-10
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.
  • Zelina, Michael

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a TFLT.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

61.

Ocular surface interferometry (OSI) devices and systems for imaging and measuring ocular tear film layer thickness(es)

      
Numéro d'application 12798324
Numéro de brevet 08215774
Statut Délivré - en vigueur
Date de dépôt 2010-04-01
Date de la première publication 2010-10-14
Date d'octroi 2012-07-10
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.
  • Zelina, Michael

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

62.

Ocular surface interferometry (OSI) methods for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 12798325
Numéro de brevet 08545017
Statut Délivré - en vigueur
Date de dépôt 2010-04-01
Date de la première publication 2010-10-14
Date d'octroi 2013-10-01
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

63.

Ocular surface interferometery (OSI) devices and systems for imaging, processing, and/or displaying an ocular tear film

      
Numéro d'application 12798275
Numéro de brevet 08746883
Statut Délivré - en vigueur
Date de dépôt 2010-04-01
Date de la première publication 2010-10-07
Date d'octroi 2014-06-10
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Weber, William L.
  • Chinnock, Randal B.
  • Gravely, Benjamin T.
  • Grenon, Stephen M.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a tear film layer thickness (TFLT), including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT).

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
  • A61B 3/02 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure subjective, c.-à-d. appareils de d’examen nécessitant la participation active du patient
  • A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio

64.

OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES, SYSTEMS, AND METHODS FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM AND/OR MEASURING OCULAR TEAR FILM LAYER THICKNESS (ES)

      
Numéro d'application US2010029645
Numéro de publication 2010/115008
Statut Délivré - en vigueur
Date de dépôt 2010-04-01
Date de publication 2010-10-07
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Weber, William, L.
  • Chinnock, Randal, B.
  • Gravely, Benjamin, T.
  • Grenon, Steven, M.

Abrégé

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.

Classes IPC  ?

  • A01N 57/26 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques du phosphore comportant des liaisons phosphore-azote

65.

METHODS, APPARATUSES, AND SYSTEMS FOR REDUCING INTRAOCULAR PRESSURE AS A MEANS OF PREVENTING OR TREATING OPEN-ANGLE GLAUCOMA

      
Numéro d'application US2009059342
Numéro de publication 2010/042398
Statut Délivré - en vigueur
Date de dépôt 2009-10-02
Date de publication 2010-04-15
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Friedland, Beth
  • Korb, Donald, R.
  • Grenon, Steve
  • Jans, John
  • Gausmann, Keith
  • Willis, Timothy R.

Abrégé

Embodiments include methods, apparatuses, and systems for reducing elevated intraocular pressure (lOP) in a patient to either prevent or treat open-angle glaucoma. Heat or a combination of heat and force is applied to the trabecular meshwork in the patient's eye without damaging proteins in the trabecular meshwork. The application of heat alone or with force to the trabecular meshwork has the effect of relaxing or loosening protein clogs or other inhibitors in the trabecular meshwork, which are either reducing or obstructing of the outflow of aqueous humor, thereby increasing the patient's IOP and causing ocular hypertension (OHT).

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

66.

Tear film measurement

      
Numéro d'application 11900314
Numéro de brevet 08192026
Statut Délivré - en vigueur
Date de dépôt 2007-09-11
Date de la première publication 2008-12-25
Date d'octroi 2012-06-05
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Gravely, Benjamin T.
  • Korb, Donald R.

Abrégé

The disclosure comprises a method for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking. Light is directed to the lipid layer of a patient's eye with an illuminator. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.

Classes IPC  ?

  • A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

67.

Tear film measurement

      
Numéro d'application 11820664
Numéro de brevet 07758190
Statut Délivré - en vigueur
Date de dépôt 2007-06-20
Date de la première publication 2008-12-25
Date d'octroi 2010-07-20
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Gravely, Benjamin T.

Abrégé

The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer. In order to facilitate ease of measurement, the patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the patient's eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

68.

TEAR FILM MEASUREMENT

      
Numéro d'application US2008057578
Numéro de publication 2008/156883
Statut Délivré - en vigueur
Date de dépôt 2008-03-20
Date de publication 2008-12-24
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Gravely, Benjamin, T.

Abrégé

Apparatus for measuring the relative thickness of the lipid layer of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking An illuminator directs light to the lipid layer of an eye The illuminator is a broad spectrum source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable The collector produces output representative of the specularly reflected light for further analysis, such as projection on to a high resolution monitor or computer analysis The patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

69.

TEAR FILM MEASURMENT

      
Numéro d'application US2008057581
Numéro de publication 2008/156884
Statut Délivré - en vigueur
Date de dépôt 2008-03-20
Date de publication 2008-12-24
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Gravely, Benjamin, T.
  • Korb, Donald, R.

Abrégé

Method for measuring the relative thickness of the lipid layer of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking Light is directed to the lipid layer with an illuminator which is a broad spectrum source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable The collector produces an output representative of the specularly reflected light for further analysis, such as projection on to a high resolution monitor or computer analysis The patient's head may be positioned on an observation platform when the illuminator directs light to the lipid layer of the eye.

Classes IPC  ?

  • A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient

70.

LIPIVIEW

      
Numéro d'application 976846
Statut Enregistrée
Date de dépôt 2008-07-28
Date d'enregistrement 2008-07-28
Propriétaire TearScience, Inc. (USA)
Classes de Nice  ?
  • 05 - Produits pharmaceutiques, vétérinaires et hygièniques
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Pharmaceutical preparations for the prevention and treatment of ocular disorders, namely, dry eye and meibomian gland dysfunction; nutraceuticals for the prevention and treatment of ocular disorders, namely, dry eye and meibomian gland dysfunction; ophthalmic preparations, eye drops, and medicated eye gels and medicated gels applied to the meibomian glands used for the treatment of ocular disorders, namely, dry eye and meibomian gland dysfunction; vitamins. Computer hardware and software, and parts and accessories therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction. Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction. Education services, namely, classes, conferences, seminars, workshops, in the field of eye disease, namely, dry eye and meibomian gland dysfunction; education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; training services in the field of eye disease, namely, dry eye and meibomian gland dysfunction; training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction. Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.

71.

LIPIFLOW

      
Numéro d'application 976847
Statut Enregistrée
Date de dépôt 2008-07-28
Date d'enregistrement 2008-07-28
Propriétaire TearScience, Inc. (USA)
Classes de Nice  ?
  • 05 - Produits pharmaceutiques, vétérinaires et hygièniques
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Ophthalmic preparations, eye drops, and medicated eye gels and medicated gels applied to the meibomian glands used for the treatment of ocular disorders, namely, dry eye and meibomian gland dysfunction. Computer hardware and software, and parts and accessories therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction. Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; medical devices, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction. Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction. Education services, namely, classes, conferences, seminars, workshops, in the field of eye disease, namely, dry eye and meibomian gland dysfunction; education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; training services in the field of eye disease, namely, dry eye and meibomian gland dysfunction; training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction. Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes.

72.

METHODS, SYSTEMS, AND APPARATUSES FOR HEAT TREATMENT FOR TREATING MEIBOMIAN GLAND DYSFUNCTION

      
Numéro d'application US2008051309
Numéro de publication 2008/089327
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de publication 2008-07-24
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Grenon, Stephen, M.
  • Willis, Timothy, R.
  • Gravely, Benjamin, Tyson
  • Jans, John, Martin
  • Hutchinson, Jordan, W.
  • Gausmann, Keith

Abrégé

Apparatuses, systems, and methods of treating meibomian gland dysfunction. Heat is applied to the patient's eyelid or surrounding tissue to apply heat to the patient's meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the patient's eyelid or surrounding tissue to improve conductive heat transfer and reduce blood flow in the tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reached desired temperature levels and/or aid in reducing discomfort to the patient during treatment.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain

73.

LIPIVIEW

      
Numéro d'application 140438000
Statut Enregistrée
Date de dépôt 2008-07-22
Date d'enregistrement 2011-05-16
Propriétaire TearScience, Inc. a Delaware corporation (USA)
Classes de Nice  ?
  • 05 - Produits pharmaceutiques, vétérinaires et hygièniques
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

(1) Ophthalmic solutions, drops, and gels used for the treatment of ocular disorders, namely dry eye and meibomian gland dysfunction. (2) Computer hardware and software, and parts therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction. (3) Medical devices and parts therefor used for analyzing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for diagnosing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Camera-based imaging devices and parts therefor, used for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Temperature controller, and parts therefor, for delivering heat and controlling temperature of heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Pressure controller, and parts therefor, for applying pressure and controlling pressure applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Heating element for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; Medical device, and parts therefor, for expressing obstructions or occlusions from meibomian glands; Medical temperature controller, and parts therefor, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical pressure controller, and parts therefor, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical heater for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Medical lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction. (4) Printed instructional, educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional , educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely dry eye and meibomian gland dysfunction. (1) Education information for eye disease, namely dry eye and meibomian gland dysfunction; Education services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Education services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Training services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Training services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction. (2) Analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction.

74.

LIPIFLOW

      
Numéro d'application 140438300
Statut Enregistrée
Date de dépôt 2008-07-22
Date d'enregistrement 2011-05-16
Propriétaire TearScience, Inc. a Delaware corporation (USA)
Classes de Nice  ?
  • 05 - Produits pharmaceutiques, vétérinaires et hygièniques
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

(1) Ophthalmic solutions, drops, and gels used for the treatment of ocular disorders, namely dry eye and meibomian gland dysfunction. (2) Computer hardware and software, and parts therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction. (3) Medical devices and parts therefor used for analyzing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for diagnosing eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices and parts therefor used for monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Camera-based imaging devices and parts therefor, used for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Temperature controller, and parts therefor, for delivering heat and controlling temperature of heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Pressure controller, and parts therefor, for applying pressure and controlling pressure applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Heating element for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; Medical device, and parts therefor, for expressing obstructions or occlusions from meibomian glands; Medical temperature controller, and parts therefor, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical pressure controller, and parts therefor, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical fluid transfer controller, and parts therefor, for controlling transferring heated fluid to the eye for delivering and controlling heat applied to meibomian glands for treating eye disease, namely, dry eye and meibomian gland dysfunction; Medical heater for applying heat to a patient's eye or related eye structure for treating eye diseases, namely dry eye and meibomian gland dysfunction; Medical lens containing a heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction. (4) Printed instructional, educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials in the field of eye disease, namely dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely dry eye and meibomian gland dysfunction. (1) Education information for eye disease, namely dry eye and meibomian gland dysfunction; Education services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Education services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction; Training services in the field of eye disease, namely dry eye and meibomian gland dysfunction; Training services, namely providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely dry eye and meibomian gland dysfunction. (2) Analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction.

75.

TREATMENT OF MEIBOMIAN GLANDS

      
Numéro d'application US2007000525
Numéro de publication 2008/085162
Statut Délivré - en vigueur
Date de dépôt 2007-01-09
Date de publication 2008-07-17
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Willis, Timothy, R.
  • Grenon, Stephen, M.

Abrégé

In one embodiment consistent with the present invention a method of treating mammalian meibomian glands (10) involves clearing the glands by applying a regulated heat (104) to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state and maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated to express fluid from the glands (108), wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) (112) can then be used to assist in maintaining proper flow of lipids from the glands. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)

76.

TEARSCIENCE

      
Numéro de série 77508554
Statut Enregistrée
Date de dépôt 2008-06-26
Date d'enregistrement 2011-08-30
Propriétaire TEARSCIENCE, INC. ()
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Computer hardware and software, and parts and accessories therefor, for use with analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction Medical apparatuses and devices, and parts and accessories therefor, used for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices in the nature of a system comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction sold as a unit Printed [ instructional, ] educational [ and teaching ] materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction [ Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; ] Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes

77.

Inner eyelid treatment for treating meibomian gland dysfunction

      
Numéro d'application 12015558
Numéro de brevet 07981146
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de la première publication 2008-05-15
Date d'octroi 2011-07-19
Propriétaire TearScience Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Gravely, Benjamin Tyson

Abrégé

A method of treating meibomian gland dysfunction. Heat is applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61F 7/08 - Bassinoires, coussinets ou tapis chauffantsBouillottes

78.

Inner eyelid heat and pressure treatment for treating meibomian gland dysfunction

      
Numéro d'application 12015567
Numéro de brevet 07976573
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de la première publication 2008-05-15
Date d'octroi 2011-07-12
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.

Abrégé

A method of treating meibomian gland dysfunction. Heat is applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the inside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61F 7/08 - Bassinoires, coussinets ou tapis chauffantsBouillottes

79.

Heat treatment and heat loss reduction for treating meibomian gland dysfunction

      
Numéro d'application 12015584
Numéro de brevet 08007524
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de la première publication 2008-05-15
Date d'octroi 2011-08-30
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Jans, John Martin

Abrégé

A method of treating meibomian gland dysfunction. Heat is applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force may also be applied to the tissue proximate the patient's meibomian glands to improve conductive heat transfer and reduce blood flow in the tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands while reducing the amount of time to reached desired temperature levels and/or aid in reducing discomfort to the patient during treatment.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61F 7/08 - Bassinoires, coussinets ou tapis chauffantsBouillottes

80.

System for inner eyelid treatment of meibomian gland dysfunction

      
Numéro d'application 12015600
Numéro de brevet 09314369
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de la première publication 2008-05-15
Date d'octroi 2016-04-19
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Jans, John Martin
  • Hutchinson, Jordan W.
  • Gausmann, Keith

Abrégé

A system for treating meibomian gland dysfunction. A controller controls a lid warmer attached onto a patient's eye to generate heat on the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. An eyecup may be employed to generate a force on the outside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61F 7/12 - Dispositifs pour chauffer ou refroidir les cavités internes du corps
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons

81.

System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction

      
Numéro d'application 12015721
Numéro de brevet 08137390
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de la première publication 2008-05-15
Date d'octroi 2012-03-20
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Jans, John Martin

Abrégé

A system for treating meibomian gland dysfunction. A controller controls heat applied to the tissue proximate the patient's meibomian glands to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. A force is also applied to tissue proximate the patient's meibomian glands during the application of heat to improve conductive heat transfer and reduce blood flow in tissue that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions. Reaching increased temperature levels may improve the melting, loosening, or softening of obstructions or occlusions in the meibomian glands. Reducing the amount of time to reached desired temperature levels an aid in reducing discomfort to the patient during treatment.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

82.

System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction

      
Numéro d'application 12015675
Numéro de brevet 08128673
Statut Délivré - en vigueur
Date de dépôt 2008-01-17
Date de la première publication 2008-05-15
Date d'octroi 2012-03-06
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Grenon, Stephen M.

Abrégé

A system for treating meibomian gland dysfunction. A controller controls heat applied to the inside of the eyelid to provide conductive heat transfer to the meibomian glands. The application of heat assists in the expression of obstructions or occlusions in the meibomian glands to restore sufficient sebum flow to the lipid layer to treat dry eye. Temperatures at the meibomian glands reach desired levels more quickly and efficiently when heating the inside of the eyelid. Reaching such higher temperature levels may be instrumental in removing obstructions in the meibomian glands. Less time may also be required to reach desired temperature levels when applying heat to the inside of the eyelid. A force may also be applied to the inside of the patient's eyelid to improve conductive heat transfer and reduce blood flow in the eyelid that causes convective heat loss. Thus, the application of force can further increase the temperature level and/or reduce the time to reach desired temperature levels for removing obstructions.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

83.

Method and apparatus for treating gland dysfunction employing heated medium

      
Numéro d'application 11931398
Numéro de brevet 09060843
Statut Délivré - en vigueur
Date de dépôt 2007-10-31
Date de la première publication 2008-05-08
Date d'octroi 2015-06-23
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.

Abrégé

A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61B 7/00 - Instruments d'auscultation
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons

84.

METHOD AND APPARATUS FOR DIAGNOSING MEIBOMIAN GLAND DYSFUNCTION

      
Numéro d'application US2007000495
Numéro de publication 2008/042002
Statut Délivré - en vigueur
Date de dépôt 2007-01-09
Date de publication 2008-04-10
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Gravely, Benjamin, T.
  • Jans, John, M.
  • Gausmann, Keith, H.

Abrégé

An apparatus for testing meibomian glands in the eyelids of humans for meibomian gland disease is provided The apparatus comp꧀ses a handle, and a probe tip mounted for movement relative to said handle such that when the probe tip is placed against the eyelid and compressive force is applied, movement of the handle a preselected distance replicates the force required for natural expression of secretion from the meibomian gland An indicator means selected from the group consisting of auditory, visual and tactile signals is provided and when activated alerts the clinician that the required force has been reached According to the method of the present invention a probe tip is located in contacting relation with the eyelid, the probe tip being connected to a handle (105) When pressure is exerted on the eyelid by pressing it against the eyelid, a preselected pressure is exerted thereon

Classes IPC  ?

  • A61B 3/16 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p. ex. tonomètres

85.

Meibomian gland illuminating and imaging

      
Numéro d'application 11893669
Numéro de brevet 08255039
Statut Délivré - en vigueur
Date de dépôt 2007-08-17
Date de la première publication 2008-04-03
Date d'octroi 2012-08-28
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Gravely, Benjamin T.
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Jans, John M.
  • Korb, Donald R.

Abrégé

In an illustrative embodiment, an apparatus for imaging a portion of a mammalian eyelid has an eye contact lenspiece configured to direct the light through an eyelid from posterior to anterior surface to thereby trans-illuminate the eyelid, when the light source illuminates the contact lens. An imaging device receives an image of the eyelid as it is trans-illuminated. Other methods and apparatus are presented in various embodiments, hence this abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

86.

Meibomian gland imaging

      
Numéro d'application 11540422
Numéro de brevet 08249695
Statut Délivré - en vigueur
Date de dépôt 2006-09-29
Date de la première publication 2008-04-03
Date d'octroi 2012-08-21
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Willis, Timothy R.
  • Gravely, Benjamin T.
  • Korb, Donald R.

Abrégé

A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61B 6/00 - Appareils ou dispositifs pour le diagnostic par radiationsAppareils ou dispositifs pour le diagnostic par radiations combinés avec un équipement de thérapie par radiations

87.

MEIBOMIAN GLAND IMAGING

      
Numéro d'application US2007000505
Numéro de publication 2008/039220
Statut Délivré - en vigueur
Date de dépôt 2007-01-09
Date de publication 2008-04-03
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Wills, Timothy, R.
  • Gravely, Benjamin, T.
  • Korb, Donald, R.

Abrégé

A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland (20) in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland (20). This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil

88.

PROVIDING GAS AND VAPOR TO A PATIENT

      
Numéro d'application US2007000508
Numéro de publication 2008/039221
Statut Délivré - en vigueur
Date de dépôt 2007-01-09
Date de publication 2008-04-03
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Foshee, David
  • Korb, Donald, R.
  • Willis, Timothy, R.
  • Barrier, Omer, Jack

Abrégé

Consistent with certain embodiments, an apparatus provides regulated heat to at least one of a patient's eyelids, using a heater unit (38) having a heating element (42) that produces heat that is transferred to the patient's eyelid when an electrical signal is applied thereto. A temperature regulator applies an electrical signal to the heating elements (42) in order to achieve heating of the heating elements (42) to a specified temperature range. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

89.

METHOD AND APPARATUS FOR TREATING MEIBOMIAN GLAND DYSFUNCTION EMPLOYING FLUID

      
Numéro d'application US2007000493
Numéro de publication 2008/027069
Statut Délivré - en vigueur
Date de dépôt 2007-01-09
Date de publication 2008-03-06
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Grenon, Stephen, M.
  • Roe, Steven
  • Korb, Donald, R.
  • Paul, Lyle

Abrégé

According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice (O). The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is applied to the exterior surface of the eyelid, proximate to the gland channel orifice (O), a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed.

Classes IPC  ?

  • B08B 3/10 - Nettoyage impliquant le contact avec un liquide avec traitement supplémentaire du liquide ou de l'objet en cours de nettoyage, p. ex. par la chaleur, par l'électricité ou par des vibrations

90.

METHOD AND APPARATUS FOR TREATING GLAND DYSFUNCTION

      
Numéro d'application US2006032544
Numéro de publication 2008/024100
Statut Délivré - en vigueur
Date de dépôt 2006-08-21
Date de publication 2008-02-28
Propriétaire TEARSCIENCE, INC. (USA)
Inventeur(s)
  • Korb, Donald, R.
  • Willis, Timothy, R.
  • Gravely, Benjamin, T.
  • Grenon, Stephen, M.

Abrégé

A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

91.

Methods for treating meibomian gland dysfunction employing fluid jet

      
Numéro d'application 11931646
Numéro de brevet 07833205
Statut Délivré - en vigueur
Date de dépôt 2007-10-31
Date de la première publication 2008-02-28
Date d'octroi 2010-11-16
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Paul, Lyle
  • Roe, Steven
  • Korb, Donald R.

Abrégé

According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice. The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is it is applied to the exterior surface of the eyelid, proximate to the gland channel orifice, a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed. In an exemplary embodiment, the medium is water heated to a temperature of between about 42° C. and about 46° C. Depending on the particular type and composition of the obstruction, the fluid jet operates to melt or soften the obstruction and to milkingly move the corpus of the softened obstruction up the gland channel from the end opposite the meibomian gland orifice and out of the gland orifice. Repeated application of the heated fluid jet may also be necessary to soften and/or express the obstruction.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain

92.

Treatment of obstructive disorders of the eye or eyelid

      
Numéro d'application 11928681
Numéro de brevet 08950405
Statut Délivré - en vigueur
Date de dépôt 2007-10-30
Date de la première publication 2008-02-21
Date d'octroi 2015-02-10
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Willis, Timothy R.

Abrégé

In accordance with certain illustrative embodiments, methods and apparatuses of treating obstructive disorders of the structure of an eye or eyelid are disclosed. The treating may involve applying heat to the structure containing the obstructive disorder to melt an obstruction in the structure and place the obstruction in a melted state. The heat may be maintained for a time period to melt the obstruction and place the obstruction in the melted state. The structure may be treated by expressing the melted obstruction from the structure. The treating may be carried out either during the time period or after the time period when heat is applied but while the obstruction is in the melted state. In certain embodiments, the method further involves subsequently treating the structure by use of a pharmacological agent. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil

93.

LIPIVIEW

      
Numéro de série 77384342
Statut Enregistrée
Date de dépôt 2008-01-30
Date d'enregistrement 2011-02-08
Propriétaire TEARSCIENCE, INC. ()
Classes de Nice  ?
  • 09 - Appareils et instruments scientifiques et électriques
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 41 - Éducation, divertissements, activités sportives et culturelles
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Computer hardware and software, and parts and accessories therefor, for use with apparatus for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction Medical apparatuses and devices, and parts and accessories therefor, used for analyzing [, diagnosing, treating, ] and monitoring eye disease, namely, dry eye and meibomian gland dysfunction;[ Medical device, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; ] Optical and photographic apparatus and instruments, and parts and accessories therefor, namely, interferometers and cameras, for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; medical imaging apparatuses and devices comprising optical lens, camera, lamp, LED, spectrometer, used for analyzing, diagnosing, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction [ ; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction ] [ Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction ] [ Education services, namely, classes, conferences, seminars, workshops, in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Education services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Training services in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Training services, namely, providing seminars, tutorials, workshops for analyzing, diagnosing, treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction ] [ Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; ] Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes

94.

LIPIFLOW

      
Numéro de série 77384313
Statut Enregistrée
Date de dépôt 2008-01-30
Date d'enregistrement 2011-07-05
Propriétaire TEARSCIENCE, INC. ()
Classes de Nice  ?
  • 10 - Appareils et instruments médicaux
  • 16 - Papier, carton et produits en ces matières
  • 44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.

Produits et services

Medical apparatuses and devices, and parts and accessories therefor, used for [ analyzing, diagnosing, ] treating, and monitoring eye disease, namely, dry eye and meibomian gland dysfunction; Medical devices, and parts and accessories therefor, for expressing obstructions or occlusions from meibomian glands; Medical heater used primarily for medical purposes, namely, for applying heat to a patient's eye and related eye structure for treating eye diseases, namely, dry eye and meibomian gland dysfunction; Medical devices, namely, medical contact lens used primarily for medical purposes containing an electrical heating element for applying heat to meibomian glands when installed on a patient's eye for treating dry eye and meibomian gland dysfunction; electronic medical temperature controller, and parts and accessories therefor, used primarily for temperature controller purposes, namely, for delivering and controlling heat to meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical pressure controller, and parts and accessories therefor, used primarily for controlling pressure, namely, for applying and controlling pressure to the meibomian glands for use in treating eye disease, namely, dry eye and meibomian gland dysfunction; electronic medical fluid transfer controller, and parts and accessories therefor, used primarily for controlling and transferring heated fluid to the eye for use in treating eye disease, namely, dry eye and meibomian gland dysfunction [ Printed instructional, educational and teaching materials in the field of eye disease, namely, dry eye and meibomian gland dysfunction; Printed instructional, educational and teaching materials for analysis, diagnosis, treatment, and monitoring of eye disease, namely, dry eye and meibomian gland dysfunction ] [ Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of eye diseases and conditions; Medical services, namely, providing medical analysis, diagnosis, treatment, and monitoring of dry eye and meibomian gland dysfunction; ] Providing medical information related to eye disease, namely, dry eye and meibomian gland dysfunction, for educational purposes

95.

Treatment of meibomian glands

      
Numéro d'application 11541418
Numéro de brevet 07981145
Statut Délivré - en vigueur
Date de dépôt 2006-09-29
Date de la première publication 2007-02-01
Date d'octroi 2011-07-19
Propriétaire TearScience Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Grenon, Stephen M.

Abrégé

In one embodiment consistent with the present invention a method of treating mammalian meibomian glands involves clearing the glands by applying a regulated heat to an eyelid containing the meibomian glands to a temperature adequate to melt obstructions in the meibomian glands to put the obstructions in a fluid or suspension (melted) state and maintaining the heat for a time period adequate to melt the obstructions. The glands can then be mechanically treated to express fluid from the glands, wherein the treating is carried out either during the time period or after the time period but while the obstruction remains in a fluid state. Subsequent pharmacological treatment of the glands by use a pharmacological agent (topical or systemic) can then be used to assist in maintaining proper flow of lipids from the glands. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

Classes IPC  ?

  • A61M 35/00 - Dispositifs pour appliquer des agents, p. ex. des remèdes, sur le corps humain
  • A61F 7/02 - Compresses ou cataplasmes procurant de la chaleur ou du froid
  • A61F 7/08 - Bassinoires, coussinets ou tapis chauffantsBouillottes

96.

Method and apparatus for treating meibomian gland dysfunction

      
Numéro d'application 11434054
Numéro de brevet 08083787
Statut Délivré - en vigueur
Date de dépôt 2006-05-15
Date de la première publication 2007-01-18
Date d'octroi 2011-12-27
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.

Abrégé

A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain

97.

Method and apparatus for treating gland dysfunction employing heated medium

      
Numéro d'application 11434033
Numéro de brevet 08915253
Statut Délivré - en vigueur
Date de dépôt 2006-05-15
Date de la première publication 2007-01-18
Date d'octroi 2014-12-23
Propriétaire TearScience, Inc. (USA)
Inventeur(s)
  • Grenon, Stephen M.
  • Korb, Donald R.
  • Willis, Timothy R.
  • Gravely, Benjamin T.

Abrégé

A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.

Classes IPC  ?

  • A61F 7/00 - Appareils de chauffage ou de refroidissement pour traitement médical ou thérapeutique du corps humain
  • A61H 7/00 - Dispositifs de pétrissage par succionDispositifs non prévus ailleurs pour masser la peau par frottement ou brossage
  • A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
  • A61H 15/00 - Massage au moyen de rouleaux, de boules, p. ex. gonflables ou de chaînes ou de chaînes de rouleaux
  • A61N 7/00 - Thérapie par ultrasons
  • A61B 18/04 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage
  • A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p. ex. des courants à haute fréquence