Abstract

The present invention discloses a method for preparing glycollate by electro-catalyzing ethylene glycol or electro-catalytically reforming waste plastic polyethylene terephthalate (PET). The method for preparing glycollate by electro-catalytically reforming waste plastic PET includes: 1) dissolving the waste plastic PET into an alkali liquid, and carrying out solid-liquid separation after hydrolysis reaction to obtain an alkaline electrolyte containing ethylene glycol; and 2) assembling an anode catalyst, a cathode catalyst and the alkaline electrolyte containing the ethylene glycol into an electrolytic cell, and applying voltage for electrocatalytic reaction, where the ethylene glycol is oxidized at an anode to generate glycollate, and water is reduced at a cathode to generate hydrogen. The present invention firstly provides conversion of the waste plastic PET into the glycollate by means of an electrocatalysis technology in the art, and the method not only utilizes resources and energy of the waste plastic PET, but also provides a new idea for low-cost and large-scale production of glycolic acid.

IPC Classes  ?

• C25B 3/07 - Oxygen containing compounds
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 3/23 - Oxidation
• C25B 3/25 - Reduction
• C25B 11/054 - Electrodes comprising electrocatalysts supported on a carrier
• C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
• C25B 11/089 - Alloys

Abstract

A method for nanocrystallizing cannabidiol, a nanocrystallized cannabidiol suspension prepared by the method and the use of nanocrystallized cannabidiol suspension. The method for nanocrystallizing cannabidiol comprises the following steps: dissolving cannabidiol in a good solvent to obtain a cannabidiol-good solvent solution; adding the cannabidiol-good solvent solution into an aqueous solution of a stabilizer; and performing ultrasonic treatment, and then performing rotary evaporation to remove the good solvent so as to obtain the nanocrystallized cannabidiol suspension, wherein the stabilizer is selected from one or more of poloxamer, Tween, polyoxyethylene alkyl ether, polyvinylpyrrolidone, hydroxypropyl methylcellulose and chitosan. According to the nanocrystallization method, by means of the technique of nanocrystallizing insoluble drugs, the particle size of insoluble drug cannabidiol is reduced, and the cannabidiol nanosuspension is obtained. In addition, the suspension has a high solid content of nanocrystallized cannabidiol, which realizes the solubilizing effect on cannabidiol.

IPC Classes  ?

• A61K 9/10 - DispersionsEmulsions
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 31/05 - Phenols
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 47/38 - CelluloseDerivatives thereof
• A61P 25/04 - Centrally acting analgesics, e.g. opioids
• A61P 25/08 - AntiepilepticsAnticonvulsants
• A61P 25/22 - Anxiolytics

Abstract

A hydrogel microneedle patch based on a three-dimensional framework structure is provided and includes a hydrogel microneedle. A raw material of the hydrogel microneedle includes polyvinyl alcohol and aqueous dispersion of acrylic resin. the hydrogel microneedle is obtained by uniformly mixing and molding of the aqueous dispersion of acrylic resin and the polyvinyl alcohol. The hydrogel microneedle patch has good strength, excellent swelling property and puncture property. In addition, a preparation method and an application of hydrogel microneedle patch are also provided.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61L 31/04 - Macromolecular materials
• A61L 31/14 - Materials characterised by their function or physical properties

Abstract

Disclosed is a method for preparing a microneedle loaded with a drug microcrystal. The method comprises the following steps: providing a drug microcrystal with a particle size of 0.5-5 μm; dispersing the drug microcrystal in an aqueous solution of a microneedle matrix material, and removing bubbles to obtain a suspension; injecting the suspension onto a microneedle mold, making the suspension enter a pinhole unit by means of negative pressure, drying and demolding to obtain the microneedle loaded with the drug microcrystal. The method improves the stability of an insoluble drug in the microneedle and the like; meanwhile, the preparation method is simpler and easy for large-scale production and application. The method features good drug stability in the preparation process; the microneedle prepared using the method has a high drug loading capacity, and the microneedle can effectively pierce the stratum corneum of the skin, so that the drug microcrystal directly penetrates through the stratum corneum and is delivered to the subcutaneous tissue. Further disclosed is a microneedle loaded with a drug microcrystal prepared using the preparation method.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/70 - Web, sheet or filament bases
• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin

Abstract

A hydrogel microneedle patch based on a three-dimensional scaffold structure, a preparation method for a microneedle patch, and a use thereof. The microneedle patch comprises microneedles; raw materials of the microneedles comprise polyvinyl alcohol and an aqueous acrylic resin dispersion; and the aqueous acrylic resin dispersion is evenly blended with polyvinyl alcohol and shaped to obtain the microneedles. The hydrogel microneedle patch has good strength and also has excellent swelling and penetration properties.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin

Abstract

Disclosed is a method for preparing glycolate by electrocatalysis of ethylene glycol or electrocatalytic reforming of waste plastic PET. The method for preparing glycolate by electrocatalytic reforming of waste plastic PET comprises the following steps: 1) dissolving waste plastic PET in an alkaline solution, carrying out a hydrolysis reaction, carrying out solid-liquid separation, and obtaining an alkaline electrolyte containing ethylene glycol; and 2) assembling an anode catalyst, a cathode catalyst, and the alkaline electrolyte containing ethylene glycol to form an electrolytic cell, applying a voltage for electrocatalytic reaction, the ethylene glycol being oxidized at an anode to generate glycolate, and water being reduced at a cathode to generate hydrogen. The present invention introduces, for the first time in the field, converting waste plastic PET into glycolate by means of electrocatalysis. The described method achieves the resource utilization and energy recovery of waste plastic PET, while also providing a novel approach for low-cost, large-scale production of glycolic acid.

IPC Classes  ?

• C25B 3/07 - Oxygen containing compounds
• C25B 3/23 - Oxidation
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/031 - Porous electrodes
• C25B 11/054 - Electrodes comprising electrocatalysts supported on a carrier

Abstract

The present application discloses a coated microneedle with a multilayer structure, including a base, a needle tip on the base, and a functional coating. The functional coating includes a content including a water-soluble polymer material and an active ingredient, and a sustained-release layer wrapping the content. The sustained-release layer covers the needle tip. The coated microneedle can prevent a drug-containing matrix from being quickly dissolved and dispersed, prevent the active ingredient from exuding along with tissues at an action site, and increase the drug intake. The present application further discloses a method for preparing the coated microneedle and a microneedle patch including the coated microneedle.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 9/70 - Web, sheet or filament bases
• B05D 7/00 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials

Abstract

Disclosed are a heat-resistant implantable polymer microneedle and a preparation method therefor and an application thereof. The microneedle comprises a needle tip, a needle body, and a base, wherein the needle tip comprises a homogeneous system formed by mixing a biodegradable macromolecular material which has a glass transition temperature of 35-65° C. and is difficultly soluble in water and a macromolecular material having a glass transition temperature higher than that of the biodegradable macromolecular material. The microneedle has good heat resistance and puncture property.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• C08L 39/06 - Homopolymers or copolymers of N-vinyl-pyrrolidones
• C08L 1/02 - CelluloseModified cellulose

Abstract

Disclosed are a smart window foil capable of adapting to light intensity, a preparation, and a use. The smart window foil contains polymethyl methacrylate and tungsten trioxide, the tungsten trioxide comprising two states: a transparent oxidation state and a colored reduction state. After the tungsten trioxide absorbs sunlight, a transition from a colorless oxidation state to a blue reduction state is achieved, thus the smart window foil is adaptive to the intensity of sunlight to present a light color or dark color. After doping with lithium iodide, the recovery rate of the tungsten trioxide can be affected, which further affects the sensitivity of the adaptability of the smart window foil to light. The described smart window foil is transparent in both the oxidation state and blue reduction state, and can be attached to existing window glass without replacing the existing window. Moreover, said foil is easy to use, has the advantages of flexibility, self-support, low costs, no scattering, saving more energy and being environmentally friendly, etc., and has broad application prospects.

IPC Classes  ?

• C08L 33/12 - Homopolymers or copolymers of methyl methacrylate
• C08K 3/22 - OxidesHydroxides of metals
• C08K 3/16 - Halogen-containing compounds

Abstract

Disclosed are an aqueous coating having water-proof and oil-proof properties, a preparation method therefor and an application thereof. The aqueous coating comprises the following components: a hydrophobic component selected from an oil-in-water Pickering emulsion; and an oil-proof component selected from one or more of natural polysaccharide substances and polyvinyl alcohol. The present invention solves the problems of the unavailability of a water-proof and oil-proof coating which is hydrophobic, waterproof, oil-proof, green, environment-friendly, safe, and applicable in a large scale.

IPC Classes  ?

• D21H 27/10 - Packing paper
• D21H 21/16 - Sizing or water-repelling agents

Abstract

A system for early diagnosis of prostate cancer, comprising: multiple medical devices used for testing a patient to obtain test data related to one or more of prostate cancer diseases; and a computer device used for analyzing patient data obtained from the multiple medical devices and analyzing the test data by using a corresponding machine learning-based analysis technique to generate a diagnosis result, the diagnosis result being used for determining whether the patient suffers from prostate cancer. According to the present invention, early diagnosis of prostate cancer is performed on a patient by means of a machine learning method in combination with an approach of detecting the number of circulating tumor cells (CTCs) and prostate-specific antibody PSA-related parameters PSA, F/T-PSA, and PSAD in the blood; in particular, early diagnosis is performed on patients whose T-PSA content is in a gray area of 4-10 ng/mL, such that the accuracy of early diagnosis and specificity are improved, non-invasive diagnosis is achieved, and overtest and overtreatment are avoided to a great extent.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Disclosed in the present invention are a coated microneedle having a multi-layer structure, comprising: a base, a needle tip located on the base, and a functional coating; the functional coating comprises a content containing a water-soluble polymer material and an active ingredient, and a sustained-release layer wrapping the content; and the needle tip is enveloped by the sustained-release layer. The coated microneedle can prevent rapid dissolution of a drug-containing matrix, prevent active ingredients from exuding along with tissues of a site of action, and increase a drug intake amount. Also disclosed in the present invention are a preparation method for the coated microneedle and a microneedle patch comprising the coated microneedle.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/70 - Web, sheet or filament bases
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 8/73 - Polysaccharides
• A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form

Abstract

A heat-resistant implantable polymer microneedle and a preparation method therefor and an application thereof. The microneedle comprises a needle tip, a needle body, and a base; the needle tip contains a homogeneous system formed by mixing a biodegradable macromolecular material which has a glass transition temperature of 35-65°C and is difficultly soluble in water and a macromolecular material having a glass transition temperature higher than the biodegradable macromolecular material. The microneedle has good heat resistance and puncture properties.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
• A61K 47/38 - CelluloseDerivatives thereof

Abstract

4, M being selected from Ba or Sr. The nonlinear optical crystal has no symmetrical center, belongs to an orthorhombic crystal system, and has a space group Ama2. The nonlinear optical crystal is an infrared nonlinear optical crystal, and has the advantages of great nonlinear optical effect, wide light transmitting band, high hardness, good mechanical properties, breakage resistance, deliquescence resistance, easiness in processing and preserving, etc. Also disclosed in the present invention are a method for preparing the nonlinear optical crystal and application thereof.

IPC Classes  ?

• C30B 29/46 - Sulfur-, selenium- or tellurium-containing compounds
• C01B 19/00 - SeleniumTelluriumCompounds thereof
• C30B 11/02 - Single-crystal-growth by normal freezing or freezing under temperature gradient, e.g. Bridgman- Stockbarger method without using solvents
• G02F 1/355 - Non-linear optics characterised by the materials used

Abstract

The present invention discloses a hypocrellin derivative substituted both in a pen-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d: −1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition. In the same condition, the hypocrellin derivative substituted both in a pen-position and in a 2-position by an amino involved in the present invention, when used as a photosensitizer, has a stronger ability to photo-dynamically inactivate tumor cells than the first and second generation commercial photosensitizers.

IPC Classes  ?

• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• C07C 221/00 - Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
• C07C 225/32 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
• C07C 227/28 - Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from natural products
• C07C 229/16 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
• C07C 229/28 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
• C07C 241/02 - Preparation of hydrazines
• C07C 243/20 - Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of rings other than six-membered aromatic rings
• C07C 323/30 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
• C07C 323/38 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with the sulfur atom of the thio group bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
• C07D 295/13 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
• C07D 295/205 - Radicals derived from carbonic acid
• C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or

Abstract

Disclosed are an anti-microbial polyamino acid derivative or copolymer having an alternating structure and a preparation method therefor. The polyamino acid derivative or copolymer has alternating structural units and the same conformation. One of the alternating and repeating structural units is an alkaline amino acid or a derivative thereof, and the other is another amino acid, which can be altered to obtain anti-microbial polyamino acid materials that differ in hydrophilicity or hydrophobicity, material strength, degradation rate, and antimicrobial activity. In addition, the polyamino acid derivative or copolymer prepared by the method of the present invention degrades in the body into small molecule fragments which have the same conformation and still have the alternating and repeating structural units, and which are finally degraded by the body into amino acid small molecules. Such structural features ensure the structural definiteness and controllability as well as the biocompatibility and degradability of said materials, and facilitates studies on biological activity and antimicrobial mechanism.

IPC Classes  ?

• C08G 69/08 - Polyamides derived from amino carboxylic acids or from polyamines and polycarboxylic acids derived from amino carboxylic acids
• A01N 37/48 - Nitro-carboxylic acidsDerivatives thereof
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

Abstract

Provided are active peptides for promoting osteoblast proliferation, and a use thereof. The amino acid sequences of the active peptides are as shown in SEQ ID NO: 1 to SEQ ID NO: 5. The active peptides can promote osteoblast proliferation. These active peptides can further be developed into medicines, food products or health products.

IPC Classes  ?

• C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
• C12N 15/12 - Genes encoding animal proteins
• A23L 33/18 - PeptidesProtein hydrolysates
• A61K 38/39 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
• A61P 19/10 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Abstract

Disclosed are an antitumor active peptide and an application thereof. The amino acid sequence of the active peptide of the present invention is shown in SEQ. ID NO.:1 - SEQ. ID NO.:5. The active peptide provided by the present invention has good antitumor activity, and in particular, can significantly inhibit the proliferation of ovarian cancer cells, and can be used for the development of antitumor drugs and health care products.

IPC Classes  ?

• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
• A61K 38/08 - Peptides having 5 to 11 amino acids
• A61K 38/10 - Peptides having 12 to 20 amino acids
• A61K 38/39 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
• A61P 35/00 - Antineoplastic agents

Abstract

Disclosed is a hydrolyzable copolyester. The molecular segment of the copolyester contains a segment of a difficultly hydrolyzable polyester and a segment of an easily hydrolyzable polyester, and the copolyester is a random copolymer or block copolymer composed of the segment of the difficultly hydrolyzable polyester and the segment of the easily hydrolyzable polyester. The copolyester has good strength and toughness, is biodegradable, and can degrade quickly when placed in a natural water environment. Further disclosed is a preparation method for the copolyester, and an application thereof.

IPC Classes  ?

• C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
• C08G 63/16 - Dicarboxylic acids and dihydroxy compounds
• C08G 63/60 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from the reaction of a mixture of hydroxy carboxylic acids, polycarboxylic acids and polyhydroxy compounds
• C08G 63/85 - Germanium, tin, lead, arsenic, antimony, bismuth, titanium, zirconium, hafnium, vanadium, niobium, tantalum, or compounds thereof

Abstract

A linear compressor, comprising: a linear motor, a hollow stepped shaft piston (10) and a stepped hole cylinder (12). A bearing hole of the linear motor is provided on the stepped hole cylinder (12); one end of the hollow stepped shaft piston (10) is provided at an inner part of the linear motor and is fixedly connected to a mover (5) of the linear motor; and the hollow stepped shaft piston (10) slides linearly along the axial direction of the bearing hole, and another end of the hollow stepped shaft piston (10) penetrates the linear motor by means of the bearing hole, and is inserted into the stepped hole cylinder (12) to form a compression space inside an inner part of the stepped hole cylinder (12). In the present compressor, a resonant spring is placed at the inner part of the linear motor, and may effectively use an inner space of the motor, thus reducing the external dimensions of the linear compressor. The stepped hole cylinder and the motor bearing hole are integrally molded by using the form of the stepped hole cylinder, which may effectively prevent the phenomenon in which the stepped hole cylinder is stuck after being externally mounted with the hollow stepped shaft piston.

IPC Classes  ?

• F04B 35/04 - Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for the means being electric
• F04B 39/00 - Component parts, details, or accessories, of pumps or pumping systems specially adapted for elastic fluids, not otherwise provided for in, or of interest apart from, groups

Abstract

122 is, x, y, and n are natural numbers, 0

IPC Classes  ?

• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

Abstract

44, M being selected from Ba or Sr. The nonlinear optical crystal has no symmetrical center, belongs to an orthorhombic crystal system, and has space group Ama2. The nonlinear optical crystal is a nonlinear optical crystal in infrared band, and has advantages of having a great nonlinear optical effect, a wide light transmitting band, a high hardness and good mechanical properties, being less brittle and less deliquescent, being easy to process and preserve, etc. Also disclosed in the present invention are a preparation method for the nonlinear optical crystal and use thereof.

IPC Classes  ?

• C30B 29/46 - Sulfur-, selenium- or tellurium-containing compounds
• C30B 11/00 - Single-crystal-growth by normal freezing or freezing under temperature gradient, e.g. Bridgman- Stockbarger method
• G02F 1/355 - Non-linear optics characterised by the materials used

Abstract

A low carbon environmentally friendly cut tobacco low temperature expansion process, comprising the following steps: making cut tobacco raw material absorb water to obtain wet expanded cut tobacco; dispersing the wet expanded cut tobacco in a liquid medium and freezing; extracting the frozen cut tobacco and implementing freeze-drying; and rehydrating the dried cut tobacco to the required water content to obtain expanded cut tobacco. The process is characterised by: dispersing the cut tobacco after water absorption in a liquid medium and freezing can prevent clumping of cut tobacco with a high water content, such that the frozen cut tobacco is in a puffy dispersed state, greatly increasing the subsequent drying efficiency. The preparation method conditions are mild and environmentally friendly, industrial production is easy to implement, and the expanded cut tobacco obtained by means of said method has an adjustable fill rate and good dispersibility.

IPC Classes  ?

• A24B 3/18 - Other treatment of leaves, e.g. puffing, crimpling, cleaning

Abstract

Disclosed is an efficient preparation method for expanded shag. The preparation method comprises the following steps: a raw shag material absorbing water to obtain swollen shag; the swollen shag making contact and mixing with a water soluble liquid medium; drying the shag after contact and mixing with the liquid medium; and re-hydrating the dried shag to achieve a required water content and obtaining the expanded shag. The features of the method of the present invention comprise the following: A mixed solution is formed by contact between a liquid medium and water in the shag, and changing the permeability of the shag by the mixed solution can eliminate or reduce drying shrinkage stress caused by water during the drying process thereof, so as to maintain the expansion volume of the shag. The process is fast and effective with mild reaction conditions. An expansion rate of the expanded shag prepared by the method is adjustable. The efficient method achieves continuous production of expanded shag.

IPC Classes  ?

• A24B 3/18 - Other treatment of leaves, e.g. puffing, crimpling, cleaning

Abstract

Disclosed is a heat-sensitive processless planographic printing plate material containing a thermosensitive protection layer. The planographic printing plate material sequentially comprises a supporting body, a hydrophilic layer, a heat-sensitive layer and a thermosensitive protection layer from the bottom up. The thermosensitive protection layer therein can not only isolate oxygen and protect the heat-sensitive layer from oxygen inhibition, but can also sense heat and allow a polymerization reaction to take place. Thus the binding force between same and the next layer is improved, so that the precision of printing plate images is high, the development performance is good, and the pressrun is high.

IPC Classes  ?

• B41N 1/12 - Printing plates or foilsMaterials therefor non-metallic other than stone
• B41C 1/10 - Forme preparation for lithographic printingMaster sheets for transferring a lithographic image to the forme
• B41N 1/08 - Printing plates or foilsMaterials therefor metallic for lithographic printing

Abstract

Disclosed in the present invention are a water-soluble chitosan antimicrobial derivative and a preparation method therefor. The water-soluble chitosan antimicrobial derivative comprises chitosan frameworks and dual-function groups for modifying amino groups on the chitosan frameworks, and the dual-function groups are guanidine groups and carbonyl methoxy polyethylene glycol. In the present invention, guanidine groups and short-chain polyethylene glycol are modified on side chains of the chitosan at the same time, and a good antimicrobial function and higher biological safety are brought to the chitosan. In the preparation method in the present invention, chitosan reacts with carbonyl methoxy polyethylene glycol first, so that the water solubility of the chitosan is fully improved, and the biological safety is greatly improved; then, a reaction with thiourea trioxide is carried out, so that graft guanidine groups in the first step are avoided, and amino groups participate in subsequence reactions, it is effectively ensured that guanidine groups have rich positive charges and the positive charge density in the water-soluble chitosan antimicrobial derivative is ensured, and accordingly, antimicrobial performance of the water-soluble chitosan antimicrobial derivative is better.

IPC Classes  ?

• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof

Abstract

The present invention discloses a hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d:(see formula I-a)(see formula I-b)(see formula I-c)(see formula I-d)The hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino prepared in the present invention has a maximum absorption wavelength of 600-650 nm and a molar extinction coefficient reaching about 20000-40000 M -1cm -1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition. In the same condition, the hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino involved in the present invention, when used as a photosensitizer, has a stronger ability to photo-dynamically inactivate tumor cells than the first and second generation commercial photosensitizers.

IPC Classes  ?

• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61P 35/00 - Antineoplastic agents
• C07C 221/00 - Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
• C07C 225/32 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
• C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
• C07C 251/24 - Compounds containing nitrogen atoms doubly- bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings

Abstract

Derivatives of hypocrellin with peri-position and 2-position simultaneously substituted by amino groups and a preparation method and application thereof are disclosed. The structural formula of the derivatives is as shown in the formulae I-a to I-d. The prepared derivatives of hypocrellin with peri-position and 2-position simultaneously substituted by amino groups have a maximum absorption wavelength of 600-650nm, and a molar extinction coefficient of about 20000-40000M -1cm -1. Compared with unmodified hypocrellin or hypocrellin only modified at 2-position, the prepared derivatives of hypocrellin have a significantly red-shifted absorption spectrum and a greatly enhanced molar extinction coefficient, and can efficiently produce reactive oxygen species such as singlet oxygen under a photosensitive condition. Under the same condition, the derivatives of hypocrellin with peri-position and 2-position simultaneously substituted by amino groups act as photosensitizers, and have higher photodynamic inactivation of tumor cells than the first and second generations of commercial photosensitizers.

IPC Classes  ?

• C07C 221/00 - Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
• C07C 225/32 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
• C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
• C07C 251/24 - Compounds containing nitrogen atoms doubly- bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61P 35/00 - Antineoplastic agents

Abstract

Disclosed is a new type water-soluble natural polysaccharide antibacterial material. The molecules of the new type water-soluble natural polysaccharide antibacterial material not only contain guanidyl, but also contain amino acid groups, so that the biosafety of the same is taken into consideration while the antibacterial property of chitosan is improved, and the new type water-soluble natural polysaccharide antibacterial material has a low cytotoxicity and is a green antibacterial product. Also disclosed is a method for preparing the above-mentioned material, comprising the steps of: 1) dissolving chitosan in a diluted acid solution to obtain a diluted acid aqueous solution of chitosan; 2) adding cyanamide or dicyandiamide into the diluted acid aqueous solution of chitosan obtained in step 1) for reaction; 3) adding an amino acid activation solution into the reaction system in the step 2) for amidation; 4) adding hydroxylamine hydrochloride to terminate the reaction; and 5) filtering the reaction solution and then dialyzing same with deionized water, and microwave vacuum-drying to obtain the new type water-soluble natural polysaccharide antibacterial material. The new type water-soluble natural polysaccharide antibacterial material can be prepared in a reaction kettle by a primary reaction by means of the method, and the used primary raw materials are rich in sources and low in price and are suitable for industrial production.

IPC Classes  ?

• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
• A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

Abstract

An inorganic salt-containing layered dissolving micro-needle containing inorganic salt, and a preparation method therefor. The inorganic salt-containing layered dissolving micro-needle comprises a substrate, a needle body on the substrate, and a needle tip on the needle body. The needle tip is made by mixing an inorganic salt solution, a stabilizer, a film-forming water-soluble polymer material, and a bioactive component; the needle body and the substrate are made of the film-forming water-soluble polymer material, or the film-forming water-soluble polymer material and the stabilizer. The inorganic salt-containing layered dissolving micro-needle containing inorganic salt improves the formability of a needle tip of an inorganic salt-containing micro-needle and improves stability of a bioactive component.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 47/30 - Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates

Abstract

The invention discloses a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, and a preparation method and application thereof. The amphiphilic hypocrellin derivative substituted by a group containing PEG, a quaternary ammonium salt or the like prepared according to the invention has an obvious red shift in its absorption spectrum and a significantly enhanced molar extinction coefficient, compared with the parent hypocrellin, can efficiently produce singlet state oxygen and other reactive oxygen species under photosensitive conditions; has different amphiphilicities and increased biocompatibility with cells or tissues by regulating its hydrophilicity and hydrophobicity; can meet the requirements of different clinical drugs, and solves the requirements of different drug delivery methods for different drug hydrophilicity and lipophilicity. Under identical conditions, the amphiphilic hypocrellin derivative photosensitizer according to the invention has higher ability to photodynamically inactivate tumor cells than the first and second generation commercial photosensitizers.

IPC Classes  ?

• C07C 217/12 - Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
• C07C 221/00 - Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
• C07C 225/22 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
• C07C 225/32 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
• C07C 229/18 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
• C07C 237/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
• C07C 239/14 - Hydroxylamino compounds or their ethers or esters having nitrogen atoms of hydroxylamino groups further bound to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
• C07C 243/22 - Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
• C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
• C07C 251/24 - Compounds containing nitrogen atoms doubly- bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
• C07C 251/56 - Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by doubly-bound oxygen atoms
• C07C 251/86 - Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
• C07C 309/69 - Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a carbon skeleton substituted by nitrogen atoms, not being part of nitro or nitroso groups
• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
• A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
• A61K 47/60 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
• A61P 35/00 - Antineoplastic agents
• C07C 323/25 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
• C07C 319/18 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of thiols to unsaturated compounds
• C07D 279/14 - 1,4-ThiazinesHydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
• C07D 487/08 - Bridged systems
• C07D 513/06 - Peri-condensed systems
• C07D 513/16 - Peri-condensed systems
• C07D 241/38 - Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
• C07C 50/36 - Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
• C07D 221/02 - Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups condensed with carbocyclic rings or ring systems

Abstract

Provided is a method for maintaining mesenchymal stem cell pluripotency in vitro, comprising the following steps: (1) extraction, primary culturing and subculturing of mesenchymal stem cells; (2) by means of a method combining friction orientation and epitaxial crystallization, preparing a composite membrane culture medium the surface of which has an orientation microstructure; (3) culturing mesenchymal stem cells on the composite membrane culture medium prepared in step (2).

IPC Classes  ?

• C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells

Abstract

A maskless photolithoghrapic system includes a laser point-by-point scanning exposure unit, a plane-projection exposure unit, a mobile station and a calculation control unit that decomposes a pattern to be exposed, so that a pattern portion with a precision requirement below a pre-determined threshold is exposed by the laser point-by-point scanning exposure unit, and a pattern portion with a precision requirement greater than the pre-determined threshold is exposed by the plane-projection exposure unit; when conducting laser point-by-point scanning exposure on a sample on the mobile station, the light emitted by the laser point-by-point scanning exposure unit moves relative to the sample according to the pattern portion with a precision requirement below the pre-determined threshold; and when conducting plane-projection exposure on the sample, the plane-projection exposure unit emits light with a corresponding pattern shape onto the sample according to the graph with a precision requirement greater than the pre-determined threshold.

IPC Classes  ?

• G03F 7/20 - ExposureApparatus therefor
• B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring

Abstract

A nanoassembly of a hypocrellin derivative, prepared by using a hypocrellin derivative and an amphiphile as precursors, and utilizing the self-assembly property between the amphiphile and the hypocrellin molecule to obtain the nanoassembly with a size of 20-200 nm and a maximum absorption wavelength range of 650-850 nm. The obtained nanoassembly can be used as a photosensitizer agent in photodynamic therapy for treating a tumor.

IPC Classes  ?

• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61K 9/51 - Nanocapsules
• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61P 35/00 - Antineoplastic agents

Abstract

Disclosed is a heat-sensitive processless planographic printing plate material containing a thermosensitive protection layer. The planographic printing plate material sequentially comprises a supporting body, a hydrophilic layer, a heat-sensitive layer and a thermosensitive protection layer from the bottom up. The thermosensitive protection layer therein can not only isolate oxygen and protect the heat-sensitive layer from oxygen inhibition, but can also sense heat and allow a polymerization reaction to take place. Thus the binding force between same and the next layer is improved, so that the precision of printing plate images is high, the development performance is good, and the pressrun is high.

IPC Classes  ?

• B41N 1/08 - Printing plates or foilsMaterials therefor metallic for lithographic printing

Abstract

Provided are a chitosan derivative-based disinfectant and a preparation method therefor. The disinfectant comprises 0.05 to 10 g of chitosan derivative and 100 ml of sterilized deionized water. The disinfectant can be used as a bactericidal disinfectant in medical treatment and can be used for disinfection of skin or mucous membranes and the like.

IPC Classes  ?

• A61K 31/722 - ChitinChitosan
• A61P 31/02 - Local antiseptics
• A61P 31/04 - Antibacterial agents
• A61P 31/10 - Antimycotics
• A01N 47/44 - GuanidineDerivatives thereof
• A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
• A01P 3/00 - Fungicides
• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof

Abstract

Disclosed is a preparation method for a hydrophobic inorganic powder material. The preparation method comprises the following steps: mixing and grinding an inorganic powder material and a hydrophobic material; and after grinding, uniformly coating the surface of the inorganic powder material with the hydrophobic material, and separating and removing the redundant hydrophobic material to obtain the hydrophobic inorganic powder material. The preparation method is simple, low in cost, and green and environmentally protective. Also disclosed is the hydrophobic inorganic powder material prepared and obtained by using this method, wherein the particle size of the material is 0.01-500 μm, the hydrophobic performance is excellent, and the contact angle with water can reach 150º.

IPC Classes  ?

• C09C 3/04 - Physical treatment, e.g. grinding, treatment with ultrasonic vibrations
• C09C 3/00 - Treatment in general of inorganic materials, other than fibrous fillers, to enhance their pigmenting or filling properties
• C09C 1/02 - Compounds of alkaline earth metals or magnesium
• C09C 1/40 - Compounds of aluminium
• C09C 1/00 - Treatment of specific inorganic materials other than fibrous fillers Preparation of carbon black

Abstract

Disclosed in the present invention are a highly effective non-halogen composite flame retardant and a preparation method therefor. The composite flame retardant is made up of the following raw material components by weight: 100 parts graphite-type material; 50-600 parts phosphorus-type flame retardant. Also disclosed is a preparation method for said composite flame retardant. The process of the technical solution of the present invention is simple, and the production period is short; graphite-type material is converted into a graphene-type material, realizing a composite of graphite-type material and phosphorus-type flame retardant; the composite flame retardant obtained is characterized by a high specific surface area, not agglomerating easily, being easily dispersed in ionic and non-ionic solvents, high flame retardant effectiveness, and good smoke suppression; the composite can be used as a flame retardant and enhancer in multiple types of saturated resin, unsaturated resin, hot melt adhesive, rubber and coating, and can also improve wear resistance of rubber and corrosion resistance of coatings.

IPC Classes  ?

• C08K 3/02 - Elements
• C08K 3/04 - Carbon
• C08K 3/32 - Phosphorus-containing compounds
• C08K 5/521 - Esters of phosphoric acids, e.g. of H3PO4
• C08K 5/523 - Esters of phosphoric acids, e.g. of H3PO4 with hydroxyaryl compounds

Abstract

A laser display system includes a red light semiconductor laser module (1), a green light semiconductor laser module (2), a blue light semiconductor laser module (3), a decoherence device (7, 8, 9), light valves (12, 13, 14), collimating and shaping devices (4, 5, 6), a heat dissipating modules (16-1, 16-2, 16-3), a temperature control module (17) and a semiconductor laser control module (18). The wavelength range output by the red light semiconductor laser module (1) is from 635 nm to 670 nm; the wavelength range output by the green light semiconductor laser module (2) is from 515 nm to 530 nm; the wavelength range output by the blue light semiconductor laser module (3) is from 440 nm to 460 nm.

IPC Classes  ?

• G02B 27/20 - Optical systems or apparatus not provided for by any of the groups , for optical projection, e.g. combination of mirror and condenser and objective for imaging minute objects, e.g. light-pointer
• H04N 9/31 - Projection devices for colour picture display
• G02B 27/10 - Beam splitting or combining systems
• G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for
• G03B 21/20 - Lamp housings
• G09G 3/34 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix by control of light from an independent source
• G03B 21/00 - Projectors or projection-type viewersAccessories therefor
• G03B 33/12 - Simultaneous recording or projection using beam-splitting or beam-combining systems, e.g. dichroic mirrors

Abstract

The invention discloses a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, and a preparation method and application thereof. The amphiphilic hypocrellin derivative substituted by a group containing PEG, a quaternary ammonium salt or the like prepared according to the invention has an obvious red shift in its absorption spectrum and a significantly enhanced molar extinction coefficient, compared with the parent hypocrellin, can efficiently produce singlet state oxygen and other reactive oxygen species under photosensitive conditions; has different amphiphilicities and increased biocompatibility with cells or tissues by regulating its hydrophilicity and hydrophobicity; can meet the requirements of different clinical drugs, and solves the requirements of different drug delivery methods for different drug hydrophilicity and lipophilicity. Under identical conditions, the amphiphilic hypocrellin derivative photosensitizer according to the invention has higher ability to photodynamically inactivate tumor cells than the first and second generation commercial photosensitizers.

IPC Classes  ?

• C07C 225/32 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
• C07C 229/14 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
• C07C 237/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
• C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
• C07C 251/24 - Compounds containing nitrogen atoms doubly- bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
• C07C 309/69 - Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a carbon skeleton substituted by nitrogen atoms, not being part of nitro or nitroso groups
• C07C 319/18 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of thiols to unsaturated compounds
• C07C 323/45 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms doubly-bound to the carbon skeleton

Abstract

Disclosed are a monosubstituted or polysubstituted amphiphilic hypocrellin derivative, preparation method therefor, and uses thereof. In the present invention, the amphiphilic hypocrellin derivative having substituted functional groups such as condensed ethylene glycol and quaternary ammonium salt shows in its absorption spectrum a substantial redshift and an enhanced molar extinction coefficient compared to hypocrellin precursor, and can highly effectively produce reactive oxygen species such as singlet state oxygen under light-sensitive conditions. By adjusting the hydrophobicity and hydrophilicity of said derivative, said derivative can have different amphiphilicity and enhanced biocompatibility with cells or tissues. The amphiphilic hypocrellin derivative can satisfy the requirements for different clinical medications and addresses the conflict between medicinal hydrophilicity and lipophilicity caused by different administration methods. Compared to the first and second generation commercial photosensitizer, under the same conditions, the amphiphilic hypocrellin derivative photosensitizer of the present invention has higher photodynamic capabilities in the eradication of live tumor cells.

IPC Classes  ?

• C07C 221/00 - Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
• C07C 225/32 - Compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly-bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
• C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
• C07C 251/24 - Compounds containing nitrogen atoms doubly- bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
• C07C 319/18 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of thiols to unsaturated compounds
• C07C 323/25 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
• C07C 213/06 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
• C07C 217/12 - Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61P 35/00 - Antineoplastic agents

Abstract

A maskless photolithoghrapic system in a cooperative working mode for a cross-scale structure, comprising: a laser point-by-point scanning exposure unit, a plane-projection exposure unit, a mobile station (19) and a calculation control unit (20), wherein the calculation control unit (20) decomposes a graph to be exposed, so that a graph with a precision requirement below a pre-determined threshold is exposed by the laser point-by-point scanning exposure unit, and a graph with a precision requirement greater than the pre-determined threshold is exposed by the plane-projection exposure unit; when conducting laser point-by-point scanning exposure on a sample on the mobile station (19), the light emitted by the laser point-by-point scanning exposure unit moves relative to the sample according to the graph with a precision requirement below the pre-determined threshold, thereby realizing the laser point-by-point scanning exposure of the sample; and when conducting plane-projection exposure on the sample, the plane-projection exposure unit emits light with a corresponding graph shape onto the sample according to the graph with a precision requirement greater than the pre-determined threshold, thereby realizing the plane-projection exposure of the sample.

IPC Classes  ?

• G03F 7/20 - ExposureApparatus therefor
• B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring

Abstract

A laser micro/nano processing system (100, 200, 300, 400) comprises: a laser light source used to provide a first laser beam having a first wavelength and a second laser beam having a second wavelength different from the first wavelength, with the pulse width of the first laser beam being in the range from a nanosecond to a femtosecond; an optical focusing assembly used to focus the first laser beam and the second laser beam to the same focal point; and a micro mobile platform (21) controlled by a computer. Also disclosed are a method for micro/nano-processing photosensitive materials with a laser and a method for fabricating a device with a micro/nano structure using laser two-photon direct writing technology. In the system and methods, spatial and temporal overlapping of two laser beams is utilized, so as to obtain a micro/nano structure with a processing resolution higher than that of a single laser beam, using an average power lower than that of a single laser beam.

IPC Classes  ?

• H01L 21/00 - Processes or apparatus specially adapted for the manufacture or treatment of semiconductor or solid-state devices, or of parts thereof
• B23K 26/0622 - Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses
• B23K 26/064 - Shaping the laser beam, e.g. by masks or multi-focusing by means of optical elements, e.g. lenses, mirrors or prisms
• B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing
• B23K 26/067 - Dividing the beam into multiple beams, e.g. multi-focusing
• B81C 1/00 - Manufacture or treatment of devices or systems in or on a substrate
• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• G03F 7/20 - ExposureApparatus therefor
• B23K 26/04 - Automatically aligning, aiming or focusing the laser beam, e.g. using the back-scattered light

Abstract

A laser display system. The laser display system comprises a red-light semiconductor laser module (1), a green-light semiconductor laser module (2), a blue-light semiconductor laser module (3), coherence eliminators (7, 8, 9), light valves (12, 13, 14), collimation shaping devices (4, 5, 6), heat dissipation modules (16-1, 16-2, 16-3), a temperature control module (17) and a semiconductor laser control module (18). The red-light semiconductor laser module (1) has an output wavelength range of 635 nm to 670 nm; the green-light semiconductor laser module (2) has an output wavelength range of 515 nm to 530 nm; and the blue-light semiconductor laser module (3) has an output wavelength range of 440 nm to 460 nm. The chroma triangular area can be as large as possible through adjustable wavelengths, and the display colors are richer and brighter. The laser display system has the common advantages of laser display and also has the advantages of electric excitation, high efficiency, long life, all solid states, miniaturization, low cost and adjustable color temperature, so that a larger color range coverage of laser display is realized, and the system can be used to satisfy special demands such as large-screen seamless splicing.

IPC Classes  ?

• G03B 21/20 - Lamp housings
• G02B 27/10 - Beam splitting or combining systems
• G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for

Abstract

Disclosed is a molecular glass of a spirofluorene derivative having a molecular structure as follows: formula (I), 12 can be identical or different, but on the same benzene ring the substituents cannot all be hydrogen atoms. The molecular glass has a good solubility in various polar solvents, is suitable to be made into a film; meanwhile the molecular glass has a very high glass transition temperature and meets the requirements of the photolithography processing technology. Also disclosed is a preparation method of the above-mentioned molecular glass of a spirofluorene derivative. The synthetic process of the method is simple and suitable for industrialization. Further disclosed is the use of a photo-resist with the above-mentioned molecular glass as a main material in photo-etching, wherein the molecular glass of a spirofluorene derivative with hydroxyl groups (or partly with hydroxyl groups) on the periphery thereof can be used as a negative photo-resist, and the molecular glass with the hydroxyl groups on the periphery thereof protected (or partly protected) by an acid-sensitive substituent can be used as a positive photo-resist.

IPC Classes  ?

• C07C 37/055 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by oxygen, e.g. ether group
• G03F 7/004 - Photosensitive materials
• C07C 69/708 - Ethers
• C07C 43/205 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
• C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
• C07C 67/00 - Preparation of carboxylic acid esters
• C07C 69/96 - Esters of carbonic or haloformic acids
• C07C 41/30 - Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation

Abstract

Provided is an anti-ultraviolet sheet-like cellulose material, characterized in that: the micro appearance of the cellulose material is sheet-like, the particle size thereof is 5-200 microns and the thickness is 0.01-10 microns, and the sheet-like cellulose material is able to block the transmission of ultraviolet light in the range of UVA (320-400 nm), and UVB (280-320 nm). At the same time, also provided are a method for preparing the sheet-like cellulose material and a use thereof.

IPC Classes  ?

• B27L 11/00 - Manufacture of wood shavings, chips, powder, or the likeTools therefor
• D21B 1/06 - Fibrous raw materials or their mechanical treatment by dividing raw materials into small particles, e.g. fibres by dry methods
• A61K 8/73 - Polysaccharides
• A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
• C09D 5/33 - Radiation-reflecting paints
• D06M 15/05 - Cellulose or derivatives thereof

Abstract

Disclosed in the present invention is a chemical plating method for preparing a flexible oxide film comprising the following steps: 1) pre-treating a flexible substrate film: impregnating an organic flexible film into a pure solution of a monomer of π-conjugated structure molecules; 2) dissolving a metal hydroxide with an aqueous hydrogen peroxide solution, then diluting by adding water, then adding a catalyst or radiating with an ultraviolet lamp for several minutes, stirring at normal temperature to obtain an aqueous metal peroxide complex solution; 3) impregnating the flexible substrate material obtained in step 1) on which π-conjugated structure molecules are fixed into the solution prepared in step 2), to obtain a flexible function film material. The present method has low preparation costs, strong operability, can achieve the preparation of a crystal oxide film on a flexible substrate with a large area, is suitable for batch preparation, has the possibility of industrial production and has a wide application prospect.

IPC Classes  ?

• C23C 18/00 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating

Abstract

Provided are a graphene nanosheet dispersion and a preparation method therefor. In the dispersion, the graphene nanosheet has a thickness of 0.35 - 7 nm, and is dispersed in a solvent in the form of a single layer or multiple layers. The preparation method comprises the following steps: (1) mixing graphite with a solid polymer proportionally, and grinding mechanically to obtain a mixed powder of graphene nanosheets/solid polymer; (2) adding the mixed powder of graphene nanosheets/solid polymer into a solvent capable of dissolving the polymer, so as to obtain an intermediate of graphene nanosheet dispersion; and (3) removing the solid polymer dissolved in the solvent from the obtained intermediate of the dispersion, so as to obtain the graphene nanosheet dispersion. The polymer is used as a dispersion phase in the method and promotes the stripping of graphite during grinding so as to effectively inhibit the obtained graphene nanosheets from reaggregation. The method is simple and has a low cost.

IPC Classes  ?

• C01B 31/04 - Graphite

Abstract

A method for preparing stably dispersed cellulose nanofibers comprises the following steps: 1) mixing cellulose and an organic solvent, the percentage of the cellulose being 1% to 15% in weight; 2) adding an esterification agent into the resultant mixture of step 1), the molar ratio of the esterification agent to the cellulose being from 1:0.1 to 4; and 3) physically breaking the resultant mixture of step 2) until a suspension liquid with stably dispersed cellulose nanofibers of 2-1000 nm in diameter and 10-100 μm in length is obtained, an esterification reaction of hydroxyl group(s) on the surface of cellulose fibers occurring at the time of the breaking. Also disclosed are dispersed cellulose nanofibers with improved compatibility to the matrix than the untreated cellulose and an improved strength of the composite materials.

IPC Classes  ?

• C08L 1/12 - Cellulose acetate
• D01F 2/28 - Monocomponent artificial filaments or the like of cellulose or cellulose derivativesManufacture thereof from cellulose derivatives from organic cellulose esters or ethers, e.g. cellulose acetate
• C08B 3/00 - Preparation of cellulose esters of organic acids
• C08B 3/20 - Esterification with maintenance of the fibrous structure of the cellulose
• C08B 16/00 - Regeneration of cellulose
• C08L 1/10 - Esters of organic acids

Abstract

Disclosed is a molecular glass of a spirofluorene derivative having a molecular structure as follows: formula (I), wherein each of R1-R12 is a hydrogen atom, a hydroxyl group, a methoxyl group or an acid-sensitive substituent; substituents R1-R12 can be identical or different, however, on the same benzene ring the substituents cannot all be hydrogen atoms. The molecular glass has good solubility in various polar solvents, is suitable to be made into a film; meanwhile, the molecular glass has a very high glass transition temperature and meets the requirements of photo-etching processing technology. Also disclosed is a preparation method for the above-mentioned molecular glass of a spirofluorene derivative. The synthetic process of the method is simple and suitable for industrialization. Further disclosed is the use of a photo-resist with the above-mentioned molecular glass as a main material in photo-etching, wherein the molecular glass of a spirofluorene derivative with hydroxyl groups (or partly with hydroxyl groups) on the periphery thereof can be used as a negative photo-resist, and the molecular glass with the hydroxyl groups on the periphery thereof protected (or partly protected) by an acid-sensitive substituent can be used as a positive photo-resist.

IPC Classes  ?

• C07C 69/96 - Esters of carbonic or haloformic acids
• C07C 69/712 - Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
• C07C 43/205 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
• C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
• C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings

Abstract

Disclosed is a surface plasmon resonance sensor chip, comprising a glass substrate layer, a metalized film layer, a probe molecule layer. The metalized film layer is disposed on the glass substrate layer, and the probe molecule layer is disposed on the metalized film layer. Also disclosed is a preparation method of a surface plasmon resonance sensor chip. By means of a surface plasmon resonance spectrum generated by the surface of the metalized film on the glass substrate, content of lipopolysaccharide in an aqueous solution is detected in a fast, convenient, quantitative, and ultra-sensitive way.

IPC Classes  ?

• C03C 17/38 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions at least one coating being a metal at least one coating being a coating of an organic material
• G01N 21/55 - Specular reflectivity

Abstract

Disclosed is a 9H-thioxanthen-9-one oxide derivative, having a structural formula as represented by formula (1), (2), (3) or (4); in formulas (1) and (2), R1, R2, R3, R4, R5, R6, R7, and R8 are respectively selected from one of hydrogen atom, arylamine group, aryl, and aryl-heterocyclic group; and in formulas (3) and (4), L is one of null, aryl, arylamine group, heterocyclic aryl, and aryl-silane group. Also disclosed are a preparation method and uses of the 9H-thioxanthen-9-one oxide derivative. The 9H-thioxanthen-9-one oxide derivative can be used as the organic luminescent layer of an organic electroluminescent device.

IPC Classes  ?

• C07D 335/16 - Oxygen atoms, e.g. thioxanthones
• C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
• C07D 409/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• H01L 51/50 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for light emission, e.g. organic light emitting diodes (OLED) or polymer light emitting devices (PLED)

Abstract

Disclosed are a preparation method of a heteroatom doped multifunctional carbon quantum dot, and application of the heteroatom doped multifunctional carbon quantum dot in fields of biomedicine, catalysts, and photoelectric devices. The heteroatom carbon quantum dot is prepared by using a conjugated polymer as a predecessor which is processed in a high temperature carbonization process. These carbon quantum dots comprise one or more of heteroatoms, such as N, S, Si, Se, P, As, Ge, Gd, B, Sub-box, and Te, whose absorption spectrum ranges from 300 to 850 nm, and the fluorescence emission wavelength is within a range of 350 to 1000 nm. The carbon quantum dot has a broad application prospect in serving as a new type photosensitizer, preparing photodynamic medicine for heating cancer and sterilization, photocatalytic degradation of organic pollutants, photocatalytic splitting decomposition of water for preparing hydrogen, organic polymer solar cell and quantum dot sensitization solar cell.

IPC Classes  ?

• C01B 31/02 - Preparation of carbon; Purification

Abstract

The present invention relates to a nanofibre lithium-ion battery separator with a composite structure and a preparation method therefor. The battery separator comprises a microporous film intermediate layer having thermal stability, and a first outer layer and a second outer layer which are located at the two sides of the intermediate layer, wherein the first outer layer and the second outer layer are electrospinning sprayed layers. The intermediate layer and the first outer layer and the second outer layer can be further combined through hot-pressing. The porosity of the battery separator is between 40% and 70%. The battery separator according to the present invention can be efficiently prepared in large quantities using large-flow electrospinning technology and equipment, and can be applied to small-sized and power lithium-ion batteries as a high-performance lithium-ion battery separator, to play the roles of increasing the security of batteries, reducing the internal resistance of batteries, prolonging the life cycle of batteries, improving the charging/discharging performance of batteries, etc.

IPC Classes  ?

• H01M 2/16 - Separators; Membranes; Diaphragms; Spacing elements characterised by the material
• B32B 3/12 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. apertured or formed of separate pieces of material characterised by a layer of regularly-arranged cells whether integral or formed individually or by conjunction of separate strips, e.g. honeycomb structure
• B32B 5/26 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by the presence of two or more layers which comprise fibres, filaments, granules, or powder, or are foamed or specifically porous one layer being a fibrous or filamentary layer another layer also being fibrous or filamentary
• B32B 37/06 - Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the heating method
• B32B 37/15 - Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the properties of the layers with at least one layer being manufactured and immediately laminated before reaching its stable state, e.g. in which a layer is extruded and laminated while in semi-molten state

Abstract

Provided is the near-infrared fluorescent dye having structure (I), wherein Y is O, S or NR11; Z is NR7R8 or OR9; R1, R2, R7, R8, R9, R11, and R14 are independently hydrogen, alkyl, ether group, substituted alkyl, acyl, or aryl; R3, R5, R6, R10, R12, and R13 are independently hydrogen, lower alkyl, lower alkoxy, cyano, or halogen; R4 is hydrogen, lower alkyl, ether group, lower alkoxy, substituted alkyl, acyl, cyano, phenyl, substituted phenyl, or halogen; ΧΘ represents anion. Also provided is a preparation method of the said dye. This kind of dye possesses excellent biocompatibility and photo stability, lower toxicity, longer fluorescent emission and higher fluorescence quantum yield, and is used as covalent or noncovalent fluorescent mark of biomacromolecule.

IPC Classes  ?

• C09B 11/02 - Diaryl- or triarylmethane dyes derived from diarylmethanes
• C09B 11/26 - Triarylmethane dyes in which at least one of the aromatic nuclei is heterocyclic
• G01N 33/533 - Production of labelled immunochemicals with fluorescent label
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances

Abstract

Provided is a polymer micro-needle array chip comprising a micro-needle array and a substrate on which the micro-needle array is placed; a polyacrylamide polymer with a molecular weight of 1.0x104-2.0x105, Vickers hardness of 150-600 HV and impact strength of 5-30 J/m is used as the material of the micro-needle array. The polymer micro-needle array chip has high mechanical strength and a sharp needle tip; and it can easily be dissolved or can swell on contact with a water-containing environment, which helps the drug to be released slowly in the skin.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

Abstract

A laser micro/nano processing system (100, 200, 300, 400) comprises: a laser light source used to provide a first laser beam having a first wavelength and a second laser beam having a second wavelength different from the first wavelength, with the pulse width of the first laser beam being in the range from a nanosecond to a femtosecond; an optical focusing assembly used to focus the first laser beam and the second laser beam to the same focal point; and a micro mobile platform (21) controlled by a computer. Also disclosed are a method for micro/nano-processing photosensitive materials with a laser and a method for fabricating a device with a micro/nano structure using laser two-photon direct writing technology. In the system and methods, spatial and temporal overlapping of two laser beams is utilized, so as to obtain a micro/nano structure with a processing resolution higher than that of a single laser beam, using an average power lower than that of a single laser beam.

IPC Classes  ?

• H01L 21/00 - Processes or apparatus specially adapted for the manufacture or treatment of semiconductor or solid-state devices, or of parts thereof
• B81C 1/00 - Manufacture or treatment of devices or systems in or on a substrate
• B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing
• B23K 26/067 - Dividing the beam into multiple beams, e.g. multi-focusing
• B23K 26/08 - Devices involving relative movement between laser beam and workpiece
• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• G03F 7/20 - ExposureApparatus therefor

Abstract

Disclosed is a method for preparing cellulose nanofiber capable of being stably dispersed, comprising the following steps: 1) mixing cellulose and an organic solvent, the solid content of the cellulose being 1% to 15%; 2) adding an esterification agent into the mixture in the step 1), the molar ratio of the esterification agent to the cellulose being from 1: 0.1 to 4; 3) performing physical breaking on all the reaction mixture, an esterification reaction occurring in the hydroxyl on the fibre surface of the cellulose at the same time of the breaking, until a suspension liquid containing stably dispersed cellulose nanofiber with the diameter being 2 to 1000 nm and the length being 100 to 100μm is obtained. Hydrophobization processing is performed, through an alkyl molecular chain, on the surface of the cellulose nanofiber with the surface being esterified obtained through the method of the present invention, so the disperse solvent may be DMF and may also be replaced with other solvents; in addition, during recombination with a synthetic resin, compared with unprocessed cellulose, better compatibility with the matrix is achieved, so the strength of the composite material is improved.

IPC Classes  ?

• D01F 2/00 - Monocomponent artificial filaments or the like of cellulose or cellulose derivativesManufacture thereof

Abstract

A semiconductor photocatalyst for hydrogen production from biomass derivatives by photocatalytic reforming. The atomic composition ratio thereof is M~N-Ax, wherein M~N is II-VI group elements or III-V group elements, A is one or more of the following elements: cobalt, nickel, iron, copper, chromium, palladium, platinum, ruthenium, rhodium, iridium or silver, and 0.02% ≤ x ≤ 1.0%. The semiconductor photocatalyst is prepared in situ from quantum dots by a photoreaction method without calcination.

IPC Classes  ?

• B01J 27/057 - Selenium or telluriumCompounds thereof
• B01J 27/043 - Sulfides with iron group metals or platinum group metals
• B01J 37/34 - Irradiation by, or application of, electric, magnetic or wave energy, e.g. ultrasonic waves
• C01B 3/04 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of inorganic compounds, e.g. ammonia

Abstract

Disclosed are a semiconductor photocatalyst for the photocatalytic reforming of biomass derivatives for hydrogen generation, and preparation and use thereof. The semiconductor photocatalyst has the atomic composition ratio of M~N-Ax; wherein M~N are IIB group elements to VIA group elements, or IIIA group elements to VA group elements, A being one element or more than two elements selected from the group consisting of cobalt, nickel, iron, copper, chromium, palladium, platinum, ruthenium, rhodium, iridium and silver; and 0.02% ≤ x ≤ 1.0%. The method of in-situ preparation of the highly effective semiconductor photocatalyst and catalytically reforming biomass derivatives for hydrogen generation by driving photoreaction with visible light via quantum dots is simple, fast, highly effective, inexpensive and practical. The in situ reaction can occur in sunlight without the need of harsh conditions such as calcination.

IPC Classes  ?

• C01B 3/32 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of gaseous or liquid organic compounds with gasifying agents, e.g. water, carbon dioxide, air

Abstract

A laser micro/nano processing system (100, 200, 300, 400) comprises: a laser light source used to provide a first laser beam having a first wavelength and a second laser beam having a second wavelength different from the first wavelength, with the pulse width of the first laser beam being in the range from a nanosecond to a femtosecond; an optical focusing assembly used to focus the first laser beam and the second laser beam to the same focal point; and a micro mobile platform (21) controlled by a computer. Also disclosed are a method for micro/nano-processing photosensitive materials with a laser and a method for fabricating a device with a micro/nano structure using laser two-photon direct writing technology. In the system and methods, spatial and temporal overlapping of two laser beams is utilized, so as to obtain a micro/nano structure with a processing resolution higher than that of a single laser beam, using an average power lower than that of a single laser beam.

IPC Classes  ?

• B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring
• B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing

Abstract

An electrospinning membrane machine in warp and weft directions comprises a control unit, a spinning unit and an auxiliary unit and the application process thereof are disclosed. A spinneret group in warp direction (5) and a spinneret group in weft direction (6) of the spinning unit are alternately arranged in longitudinal and transverse direction, reciprocatingly transfer, and spin fibers above the membrane collector. A high voltage electric field is applied between the spinneret groups and a stainless steel conveyer. The macromolecule polymer solution conveyed to the nozzles of the spinneret groups split into nano-jets, and then the nano-jets are collected on the conveyer under high voltage. The nano-jets form membrane on the conveyer and are transported. This machine could not only produce monolayer nano-fiber membrane, but also produce multilayer complex nano-fiber membrane.

IPC Classes  ?

• D01D 5/00 - Formation of filaments, threads, or the like

Abstract

A micro-fluid sample boat with solution storage chamber and pump , including: a chamber channel layer, a chamber channel sealing layer, a printing circuit plate jointing with magnetic sensitive sensor chip, a fluid inlet ; A waste pool ,a reaction detection chamber, a solution storage chamber and a pump and micro-channel are provided in the chamber channel layer; the said solution storage chamber and pump includes a sample storage chamber and a reagent storage chamber, the said chamber channel sealing layer and the chamber channel layer are aligned with each other and sealed ,by which the whole waste pool, reaction detection chamber, sealable solution inlet solution storage chamber and pump and micro-channel are formed. Since elastic seals are provided in the solution storage chamber, solutions in the chamber are pushed by an outer pressure into the micro-channels. Thus, the sample boat is convenient for qualitative measurement and usage.

IPC Classes  ?

• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 27/72 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor

Abstract

An apparatus for auto-detection of magnetic sensitive biochip , includes : a suppress device which applies the press to the sample closet on the biochip's sample boat directly or indirectly; a liquid injection system for injecting the liquid into the micro-fluid channels; the biochip in the micro-fluid channels , which integrates magnetic sensitive sensors ; the device produces the magnetic field ; the electron device for controlling the chip and selecting the information ; the microprocessor and the user interface.

IPC Classes  ?

• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
• G01N 27/72 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables