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Found results for
 patents
1.
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LOCAL COMPOSITION TO TREAT STRESS URINARY INCONTINENCE IN A FEMALE SUBJECT
| Application Number |
IB2013000549 |
| Publication Number |
2013/150354 |
| Status |
In Force |
| Filing Date |
2013-03-28 |
| Publication Date |
2013-10-10 |
| Owner |
TIXUPHARMA (Italy)
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| Inventor |
Ghisalberti, Carlo
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Abstract
The invention refers to compositions comprising spermidine for the treatment of the stress urinary incontinence in a female subject. The inventive compositions are conceived either for transvaginal application to release spermidine onto external sphincter, urethra and endopelvic fascia, or for intravescial instillation. A variant composition takes the form of a condom lubricant comprising spermidine for the local release thereof during sexual intercourse, being an alternative or complementary to the local self-administration.
IPC Classes ?
- A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
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2.
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GYNECOLOGIC COMPOSITION TO TREAT VULVAR VESTIBULITIS
| Application Number |
IB2013000524 |
| Publication Number |
2013/132322 |
| Status |
In Force |
| Filing Date |
2013-03-05 |
| Publication Date |
2013-09-12 |
| Owner |
TIXUPHARMA (Italy)
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| Inventor |
Ghisalberti, Carlo
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Abstract
The invention refers to novel gynecologic composition comprising spermidine to treat vulvar vestibulitis syndrome (VVS). In this therapeutic context, spermidine effective at around one micromole per applied dose in form of simple salt or complex, alone or in combination or in conjuction with auxiliary actives such as anesthetics and estrogens.
IPC Classes ?
- A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
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3.
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SUPRAMOLECULAR COMPLEXES OF POLYANIONIC POLYMERS AND SPERMIDINE IN TISSUE MAINTENANCE AND REPAIR
| Application Number |
IB2011001771 |
| Publication Number |
2012/017288 |
| Status |
In Force |
| Filing Date |
2011-08-01 |
| Publication Date |
2012-02-09 |
| Owner |
TIXUPHARMA (Italy)
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| Inventor |
Ghisalberti, Carlo
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Abstract
The invention refers to supramolecular complexes formed by polyanionic polymers and spermidine characterized by a ratio of anionic equivalents raging from 101:1 to 107: 1 eq/eq, more preferably from 102: 1 to 104:1 eq/eq, whose components are linked by non-covalent, ionic interactions. Mentioned supramolecular complexes are characterized by high potency in eliciting the fibroblast proliferation. The invention also refers to medicinal/cosmetic compositions comprising the inventive supramolecular complexes for the trophism, maintenance, regeneration, and repair of connective tissues and mucosae in damaged or senescent conditions.
IPC Classes ?
- A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
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4.
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INCLUSION COMPLEXES OF CYCLODEXTRINS WITH SPERMIDINE, AND PROLIFERATIVE/REPARATIVE COMPOSITIONS COMPRISING THEREOF
| Application Number |
IB2011001789 |
| Publication Number |
2012/017290 |
| Status |
In Force |
| Filing Date |
2011-08-01 |
| Publication Date |
2012-02-09 |
| Owner |
TIXUPHARMA (Italy)
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| Inventor |
Ghisalberti, Carlo
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Abstract
The invention refers to inclusion complexes formed by cyclodextrins with spermidine with a molar ratio ranging from 1 : 1 to 1: 10 mol/mol, preferably 1:2 mol/mol, which have a significantly enhanced proliferative/mitotic effect on fibroblasts. It further refers to medicinal/cosmetic compositions comprising said inclusion complexes for the maintenance and repair of damaged or senescent connective tissues and mucosa.
IPC Classes ?
- A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
- A61K 31/724 - Cyclodextrins
- A61K 47/40 - CyclodextrinsDerivatives thereof
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