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Résultats pour
 brevets
1.
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LOCAL COMPOSITION TO TREAT STRESS URINARY INCONTINENCE IN A FEMALE SUBJECT
| Numéro d'application |
IB2013000549 |
| Numéro de publication |
2013/150354 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2013-03-28 |
| Date de publication |
2013-10-10 |
| Propriétaire |
TIXUPHARMA (Italie)
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| Inventeur(s) |
Ghisalberti, Carlo
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Abrégé
The invention refers to compositions comprising spermidine for the treatment of the stress urinary incontinence in a female subject. The inventive compositions are conceived either for transvaginal application to release spermidine onto external sphincter, urethra and endopelvic fascia, or for intravescial instillation. A variant composition takes the form of a condom lubricant comprising spermidine for the local release thereof during sexual intercourse, being an alternative or complementary to the local self-administration.
Classes IPC ?
- A61K 31/132 - Amines, p. ex. amantadine ayant plusieurs groupes amino, p. ex. spermidine, putrescine
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2.
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GYNECOLOGIC COMPOSITION TO TREAT VULVAR VESTIBULITIS
| Numéro d'application |
IB2013000524 |
| Numéro de publication |
2013/132322 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2013-03-05 |
| Date de publication |
2013-09-12 |
| Propriétaire |
TIXUPHARMA (Italie)
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| Inventeur(s) |
Ghisalberti, Carlo
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Abrégé
The invention refers to novel gynecologic composition comprising spermidine to treat vulvar vestibulitis syndrome (VVS). In this therapeutic context, spermidine effective at around one micromole per applied dose in form of simple salt or complex, alone or in combination or in conjuction with auxiliary actives such as anesthetics and estrogens.
Classes IPC ?
- A61K 31/132 - Amines, p. ex. amantadine ayant plusieurs groupes amino, p. ex. spermidine, putrescine
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3.
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SUPRAMOLECULAR COMPLEXES OF POLYANIONIC POLYMERS AND SPERMIDINE IN TISSUE MAINTENANCE AND REPAIR
| Numéro d'application |
IB2011001771 |
| Numéro de publication |
2012/017288 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2011-08-01 |
| Date de publication |
2012-02-09 |
| Propriétaire |
TIXUPHARMA (Italie)
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| Inventeur(s) |
Ghisalberti, Carlo
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Abrégé
The invention refers to supramolecular complexes formed by polyanionic polymers and spermidine characterized by a ratio of anionic equivalents raging from 101:1 to 107: 1 eq/eq, more preferably from 102: 1 to 104:1 eq/eq, whose components are linked by non-covalent, ionic interactions. Mentioned supramolecular complexes are characterized by high potency in eliciting the fibroblast proliferation. The invention also refers to medicinal/cosmetic compositions comprising the inventive supramolecular complexes for the trophism, maintenance, regeneration, and repair of connective tissues and mucosae in damaged or senescent conditions.
Classes IPC ?
- A61K 31/132 - Amines, p. ex. amantadine ayant plusieurs groupes amino, p. ex. spermidine, putrescine
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4.
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INCLUSION COMPLEXES OF CYCLODEXTRINS WITH SPERMIDINE, AND PROLIFERATIVE/REPARATIVE COMPOSITIONS COMPRISING THEREOF
| Numéro d'application |
IB2011001789 |
| Numéro de publication |
2012/017290 |
| Statut |
Délivré - en vigueur |
| Date de dépôt |
2011-08-01 |
| Date de publication |
2012-02-09 |
| Propriétaire |
TIXUPHARMA (Italie)
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| Inventeur(s) |
Ghisalberti, Carlo
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Abrégé
The invention refers to inclusion complexes formed by cyclodextrins with spermidine with a molar ratio ranging from 1 : 1 to 1: 10 mol/mol, preferably 1:2 mol/mol, which have a significantly enhanced proliferative/mitotic effect on fibroblasts. It further refers to medicinal/cosmetic compositions comprising said inclusion complexes for the maintenance and repair of damaged or senescent connective tissues and mucosa.
Classes IPC ?
- A61K 31/132 - Amines, p. ex. amantadine ayant plusieurs groupes amino, p. ex. spermidine, putrescine
- A61K 31/724 - Cyclodextrines
- A61K 47/40 - CyclodextrinesLeurs dérivés
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