Abstract

The present invention relates to ester compounds comprising a 2-(1,5-dimethyl-4- methylenecyclopent-2-en-1-yl)ethyl core and to a composition that comprises said compounds and attracts the species Pseudococcus longispinus. The present invention also refers to an attractant device for Pseudococcus longispinus comprising said compounds or said composition, preferably incorporated in a carrier, to a method for control and/or monitoring of the populations of insects of the species Pseudococcus longispinus and to the use of the compound, composition or device of the invention for control and/or monitoring of the pest. Finally, the present invention provides a method for preparing the ester compounds of the invention.

IPC Classes  ?

• C07C 69/14 - Acetic acid esters of monohydroxylic compounds
• C07C 69/24 - Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
• A01P 17/00 - Pest repellants
• A01N 1/00 - Preservation of bodies of humans or animals, or parts thereof

Abstract

The device for storing and/or converting energy (1) comprises one or more spacers (2) defining two sides; and electrodes (3) in contact with one or both sides of the spacer (2), each electrode (3) comprising an ink including at least one conductive additive. The method comprises the following steps: preparing an ink, the ink comprising at least one conductive additive; and forming electrodes (3) with the ink, the electrodes (3) being in contact with one or both sides of one or more spacers (2). It allows the separator itself to act as a collector at the same time, providing a solution to the problem of oxidation of metal collectors, among others.

IPC Classes  ?

• H01G 11/52 - Separators
• H01G 11/02 - Hybrid capacitors, i.e. capacitors having different positive and negative electrodes; Electric double-layer [EDL] capacitors; Processes for the manufacture thereof or of parts thereof using combined reduction-oxidation reactions, e.g. redox arrangement or solion
• H01G 11/06 - Hybrid capacitors with one of the electrodes allowing ions to be reversibly doped thereinto, e.g. lithium ion capacitors [LIC]
• H01G 11/38 - Carbon pastes or blends; Binders or additives therein
• H01G 11/50 - Electrodes characterised by their material specially adapted for lithium-ion capacitors, e.g. for lithium-doping or for intercalation
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes
• H01M 4/04 - Processes of manufacture in general
• H01M 4/139 - Processes of manufacture
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodes; Lithium-ion batteries
• H01M 10/058 - Construction or manufacture
• H01M 50/46 - Separators, membranes or diaphragms characterised by their combination with electrodes
• H01G 11/36 - Nanostructures, e.g. nanofibres, nanotubes or fullerenes
• H01G 11/84 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof
• H01M 50/417 - Polyolefins
• H01M 50/429 - Natural polymers
• C09D 11/52 - Electrically conductive inks

Goods & Services

Educational software and Educational mobile applications; Interactive electronic publications; E-books; Education software; All the aforesaid goods for developing and training emotional skills. Education, entertainment and sports; Education and instruction; Publishing, reporting, and writing of texts; Education and training consultancy; Arranging and conducting of conferences, congresses and symposiums; Organisation of congresses and conferences for cultural and educational purposes; Educational examination; Publication of newspapers, periodicals, catalogs and brochures; Multimedia publishing of books; Publication and edition of books; Publishing of instructional books; Online publication of electronic books and journals; Postgraduate training courses; Educational research; Publication of instructional literature; Educational seminars; Development of educational materials; Developing educational manuals; Workshops for educational purposes; All the aforesaid services for developing and training emotional skills and wellness in infants, adolescents and young children. Science and technology services; IT services; Design, development and programming of computer software; Design and development of software in the field of mobile applications; Programming of educational software; Hosting multimedia educational content; Research and development of educational applications and games via mobile apps for developing and training emotional skills; Research and development of educational applications and games via technological platforms for developing and training emotional skills.

Abstract

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.

IPC Classes  ?

• A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61K 31/23 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

An apparatus (1) for treating a cancerous target site is provided. The apparatus comprises an electromagnetic emitter (10) comprising one or more electrodes with an electrically insulating coating for preventing electrical contact between the electrodes and the target site. The electromagnetic emitter (10) is configured to provide a tumour treating field at a target site (30) via the one or more electrodes, the tumour treating field being non-ionizing alternating electromagnetic field having a frequency of between 10 kHz to 300 kHz; and further having a magnetic flux density of between 0.1pT and 1mT. The apparatus further comprises a heat source (20) configured to provide heating at the target site to cause hyperthermia at the target site. The apparatus is configured to apply the non-ionizing alternating electromagnetic field and the heating independently. The apparatus comprises an electronic controller for electronically controlling the electromagnetic emitter and the heat source.

IPC Classes  ?

• A61N 2/00 - Magnetotherapy
• A61N 1/40 - Applying electric fields by inductive or capacitive coupling
• A61N 7/02 - Localised ultrasound hyperthermia

Abstract

The present invention relates to a layered double hydroxide comprising at least one divalent cation AII or alternatively LiI, at least one trivalent cation BIII selected from the group consisting of VIII, CoIII, CrIII, MnIII, FeIII, GaIII and lanthanides. The present invention also relates to a process for the synthesis of said layered double hydroxide and uses thereof.

IPC Classes  ?

• C01G 53/00 - Compounds of nickel

Abstract

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.

IPC Classes  ?

• A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
• A61K 31/05 - Phenols
• A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline

Abstract

The present invention relates to a compound 1 or 2 or a composition comprising same. The invention also relates to a method for obtaining compound 1 or 2, and to the use of the compounds to detect GHB in beverages. The invention also includes a device or kit for used to detect GHB in beverages.

IPC Classes  ?

• C07C 335/16 - Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
• C07C 59/01 - Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
• G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
• G01N 33/14 - Beverages

Abstract

A method for the diagnosis of systemic lupus erythematosus (SLE) based on an interfacial process of antigen-antibody molecular recognition, specifically between anti-Ro52 and Ro52 protein, in a piezoelectric resonator, for application in the diagnosis of autoimmune diseases such as SLE.

IPC Classes  ?

• G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
• G01N 33/564 - Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease
• G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

The titanium(IV) and iron(III) MOF solid MUV-17 (TiFe2), has the general formula (1): [TiIVFeIII2(O)(L)2(X)3]S, where X is each equal or different selected from: O2-, OH-, H2O, F-, Cl-, Br-, I-, NO3-, ClO4-, BF4-, SCN-, OH-, CH3COO-, C5H7O2-, SO42- and CO32-, L is a 5 tricarboxylic ligand and S is at least one molecule of a polar solvent selected from the group consisting of N,N'-dimethylformamide, N, N'-diethylformamide, N,N'-dimethylacetamide, N-methyl-2-pyrrolidone, methanol, ethanol, isopropanol, n-propanol, water and mixtures thereof. The titanium(IV) and iron(III) MOF solid has long-term catalytic activity for the degradation of toxic compounds. The method for obtaining them comprises 10 dissolving the components under anaerobic conditions. The invention also relates to the use of the titanium(IV) and iron(III) MOF solid as an additive with toxic compound detoxifying properties.

IPC Classes  ?

• C07F 7/28 - Titanium compounds
• B01J 21/06 - Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
• C07C 63/307 - Monocyclic tricarboxylic acids
• C07F 15/02 - Iron compounds

Abstract

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.

IPC Classes  ?

• A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61K 31/198 - Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
• A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
• A61P 25/00 - Drugs for disorders of the nervous system

Abstract

The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Abstract

filtering the mixture treated in the reactor, in at least one filtration tank through the gasified membrane under conditions such that the relationship between the biogas recirculated per square meter of membrane, and time unit, and the wastewater filtered—SGDp—is the minimum value allowed by the solid concentration in a treatment plant.

IPC Classes  ?

• C02F 3/28 - Anaerobic digestion processes
• C02F 3/00 - Biological treatment of water, waste water, or sewage

Abstract

The present invention relates to a method for the diagnosis of systemic lupus erythematosus (SLE), which is a diagnostic method based on an interfacial process of antigen-antibody molecular recognition, specifically between anti-Ro52 and Ro52 protein, in a piezoelectric resonator, for use in the diagnosis of autoimmune diseases such as SLE.

IPC Classes  ?

• G01G 3/13 - Weighing apparatus characterised by the use of elastically-deformable members, e.g. spring balances wherein the weighing element is in the form of a solid body stressed by pressure or tension during weighing having piezoelectric or piezo-resistive properties
• G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
• G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor

Abstract

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.

IPC Classes  ?

• A61K 31/05 - Phenols
• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
• A61K 31/7052 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
• C07C 15/52 - Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic part substituted by unsaturated hydrocarbon radicals polycyclic non-condensed containing a group with formula
• C07C 39/205 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic part, with unsaturation outside the rings
• C07H 19/02 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof sharing nitrogen
• C07H 19/048 - Pyridine radicals

Abstract

R. solanacearum in river courses and irrigation water, as well as in a method for preventing and/or controlling the wilt produced by the bacteria, in which at least one of the bacteriophages, or combinations thereof, are delivered to the plants and/or the soil in the irrigation water.

IPC Classes  ?

• C12N 7/00 - Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
• A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
• A01M 7/00 - Special adaptations or arrangements of liquid-spraying apparatus for purposes covered by this subclass
• A01G 25/02 - Watering arrangements located above the soil which make use of perforated pipe-lines or pipe-lines with dispensing fittings, e.g. for drip irrigation
• A01G 25/06 - Watering arrangements making use of perforated pipe-lines located in the soil
• A01G 27/00 - Self-acting watering devices, e.g. for flower-pots
• A01G 31/00 - Soilless cultivation, e.g. hydroponics

Abstract

The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof, a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.

IPC Classes  ?

• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61P 35/00 - Antineoplastic agents
• A61K 31/225 - Polycarboxylic acids
• A61K 31/277 - Nitriles; Isonitriles having a ring, e.g. verapamil
• A61K 31/42 - Oxazoles
• A61K 31/4412 - Non-condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
• A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
• A61K 31/635 - Compounds containing para-N-benzene- sulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonohydrazide having a heterocyclic ring, e.g. sulfadiazine

Abstract

The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Abstract

The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Abstract

The present invention refers to an anaerobic process with filtration procedure for wastewater treatment at room temperature, that comprises: - continuously feeding at least one anaerobic reactor, with previously sieved wastewater and feeding biodegradable organic waste - BOW - also previously sieved, said reactor being coupled to at least one gasified filtration membrane, with recirculation of biogas from the reactor, - carrying out the anaerobic digestion of the organic fraction contained in the mixture of wastewater and the BOW, in the reactor, obtaining a treated mixture and - filtering the mixture treated in the reactor, in at least one filtration tank through the gasified membrane under conditions such that the relationship between the biogas recirculated per square meter of membrane, and time unit, and the wastewater filtered - - SGDp - is the minimum value allowed by the solid concentration in a treatment plant.

IPC Classes  ?

• C02F 3/28 - Anaerobic digestion processes

Abstract

The invention relates to a device comprising a multi-mode waveguide structure with a number N of single-mode inlet and outlet waveguides (10, 20) to allow the propagation of an optical series injected into the optical multi-mode interference coupler device (1), or MMI coupler, wherein a series of multiple images of the injected optical signal is formed in an interior area thereof. According to the invention, the MMI coupler (1) comprises a unit (15) for generating a travelling surface acoustic wave (SAW) that hits the interior area of the MMI coupler (1) to modulate with an opposite phase the effective refraction index of the multiple images formed, the images being separated by a distance determined according to the expression: λSAW/2+nλSAW.

IPC Classes  ?

• G02B 6/26 - Optical coupling means

Abstract

The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof,a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.

IPC Classes  ?

• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof,a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.

IPC Classes  ?

• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61P 35/00 - Antineoplastic agents

Abstract

The invention relates to a method for the prevention and/or the biological control of wilt caused by Ralstonia solanacearum, via the use of bacteriophages suitable for this purpose, and to the structural characterisation, genome sequence and activity of three specific lytic bacteriophages of R. solanacearum. It relates to podovirus which, between 4º C and 30º C, presents an elevated stability in an aqueous medium in the absence of a host. As a result of the high level of stability, lytic activity, elevated specificity towards R. solanacearum and the absence of activity against the microbiota associated with the plants to be protected, the invention proposes the use thereof for the biological control of R. solanacearum in river courses and irrigation water, as well as a method for preventing and/or controlling the wilt produced by said bacteria, in which at least one of said bacteriophages, or combinations thereof, are delivered to the plants and/or the soil in the irrigation water.

IPC Classes  ?

• C12N 7/00 - Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof

Abstract

The invention relates to a lichen extract and to the use of same for improving the recovery of microorganisms associated with lichens. In this way, the invention relates to a method for improving or optimising the isolation and/or culture of microorganisms associated with lichens, which comprises the processing of lichen thalli which are washed, or washed and chopped, in a culture medium comprising the lichen extract of a population of the species of lichen from which the microorganisms are to be isolated. The invention also relates to the method for obtaining the lichen extract and to the composition comprising the lichen extract thus obtained.

IPC Classes  ?

• A01H 15/00 - Fungi; Lichens
• C12N 1/00 - Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor

Abstract

Compound for treatment of myotonic dystrophy type The present invention relates to a compound, or a salt thereof, and a pharmaceutical composition comprising said compound, or a salt thereof, for use in the prevention and/or treatment of myotonic dystrophy type 1 in a patient, in particular by reducing the levels of autophagy and apoptosis that are elevated in myotonic muscular dystrophy type 1.

IPC Classes  ?

• A61K 31/198 - Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
• A61K 31/4439 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 31/4745 - Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system

Abstract

The invention relates to a device for attaching a macroporous material for regenerating articular cartilage to the subchondral bone, characterised in that it includes: a) a sponge which comprises a biocompatible macroporous material that is suitable for regenerating articular cartilage, b) an attachment system suitable for attaching the device to the subchondral bone, and c) a supporting part suitable for connecting the sponge to the attachment system. The device according to the invention enables the regeneration of articular cartilage, providing a good system for attachment to the chondral bone, while avoiding damage to the sponge material when attaching the device to the bone.

IPC Classes  ?

• A61B 17/68 - Internal fixation devices
• A61F 2/30 - Joints
• A61L 27/56 - Porous or cellular materials
• A61L 27/58 - Materials at least partially resorbable by the body

Abstract

Use of the phenantrenic alkaloids seconeolitsine and N-methyl-seconeolitsine for the manufacture of medicaments. More particularly the use is described of the said compounds for the manufacture of antibiotics, especially for the treatment of diseases caused by Gram-positive bacteria, preferably Streptococcus pneumoniae or Staphylococcus aureus. The application thereof is of special relevance for producing medicaments for the treatment of pneumonia.

IPC Classes  ?

• C07D 317/70 - Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
• A61K 31/36 - Compounds containing methylenedioxyphenyl groups, e.g. sesamin
• A61P 31/04 - Antibacterial agents

Abstract

The present invention relates to a method and kits for determining the concentration of anionic surfactants in water or aqueous media by promoting the formation of foam attributable to the same and as a function of the period for disappearance of the foam ring formed on the surface of the water or aqueous medium. For this purpose there is added to a sample of water or aqueous medium a promoter of production of foam attributable to the anionic surfactant to which there has previously been added a buffer to maintain the pH during the test period at a value ≤ 6.

IPC Classes  ?

• G01N 33/18 - Water
• G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods using chemical indicators
• G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
• G01N 13/00 - Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects

Abstract

The invention relates to the compression of colour images, based on non-linear perceptual representations and machine learning. More specifically, the invention relates to a method for the compression of colour images, comprising the following steps: (1) expressing the coefficients of a local space/frequency representation of the opposing chromatic and achromatic channels in units of perceptual contrast; (2) applying a non-linear transform with divisive normalisation to each channel, such that they include relationships between the coefficients of the achromatic and chromatic contrast channels; and (3) using statistical learning algorithms to select the relevant data from the non-linearly normalised channels. Psychophysical and numerical experiments have been conducted in order to estimate and validate the parameters of the divisive normalisation and contrast transforms. In addition, the above method has been compared experimentally with a JPEG implementation. In both cases, 16x16 DCT blocks were used and, in each case, comparable values were used for the frequency-dependent and chromatic transform parameters. Under these conditions, the experimental results provide an average compression gain of 50% in relation to JPEG for different distortion measurements (RMSE, SSIM and S-CIELab) in the realistic commercial range of [1, 2.2] bits/pix. The invention also relates to the apparatus and code used to implement said method.

IPC Classes  ?

• H04N 7/30 - involving transform coding (H04N 7/50 takes precedence;digital computers for performing complex mathematical operations, e.g. domain transformation, G06F 17/14)
• H03M 7/30 - Compression; Expansion; Suppression of unnecessary data, e.g. redundancy reduction
• G06T 9/00 - Image coding
• H04N 7/32 - involving predictive coding (H04N 7/48, H04N 7/50 take precedence);;
• H04N 7/34 - using spatial prediction

Abstract

The invention relates to homo and heterometallic soluble coordination polymers containing an oxalate ligand and to a method for obtaining spinels from same. The homo and heterometallic coordination polymers, which contain at least one oxalate ligand, are characterised in that they also contain at least one organic molecule capable of stabilising expanded metal complex structures through the formation of supramolecular interactions such that the polymer is substantially soluble in water and insoluble in organic solvents. Said polymers, when in the solid state, can generate spinel-type metal oxides or other mixed oxides following a thermal oxidation treatment including steps comprising: the preparation of an alcoholic solution of a metal complex containing at least one oxalate ligand and a metal salt, the precipitation of the metal complex and the metal salt with a cryptand-type molecule through the formation of a coordination polymer that is soluble in water and insoluble in organic solvents, the separation of the precipitate obtained in the previous step, and the heating of same in an oxidant atmosphere to a temperature of at least 350ºC until the spinel or mixed oxide has formed.

IPC Classes  ?

• C08G 79/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon
• C01B 13/32 - Methods for preparing oxides or hydroxides in general by oxidation or hydrolysis of elements or compounds in the liquid or solid state

Abstract

The invention relates to plasmonic nanocomposites based on polymer and metal nanoparticles for lithographic use. More specifically, the invention relates to a method for the synthesis of a nanocomposite formed by a polymer with noble metal nanoparticles embedded therein. The method is characterised in that the noble metal reduction reaction, which produces the nanoparticles, and the polymer chain cross-linking, which forms the polymer matrix, occur simultaneously as a result of the heating generated during the irradiation process, thereby enabling the generation of nanostructures using a standard lithographic process. The invention also relates to the resulting nanocomposites and to the uses thereof in different technical fields.

IPC Classes  ?

• G03F 7/00 - Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printed surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
• B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units

Abstract

The invention relates to a method for the production and purification of PEDF molecules and mutated and/or truncated versions of said molecule in a yeast expression system. The invention also relates to the protection of the PEDF molecules directly obtained and to the use of same in the preparation of pharmaceutical compositions. The method includes the following steps in which: the PEDF cDNA is obtained at least from cells of the retinal pigmented epithelium, mutant and/or truncated versions are obtained, the structures are cloned into a yeast expression vector, the yeast clones are transformed and selected, the yeast culture medium is inoculated with the clones obtained, the intact or truncated PEDF factor is induced in the yeast, the cells are eliminated from the culture by means of centrifugation, the culture medium containing the intact and/or truncated PEDF factor is changed, and said PEDF factor is purified and isolated.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
• C07K 14/81 - Protease inhibitors
• A61K 38/57 - Protease inhibitors from humans
• A61P 27/02 - Ophthalmic agents

Abstract

The invention relates to a method for the synthesis of inert metal nanoparticles. More specifically, the invention relates to a method for obtaining stable colloids of inert metal nanoparticles in a single step comprising the laser ablation of a solid target submerged in a liquid medium containing metal salts. The invention also relates to the nanoparticles synthesised using the aforementioned method and characterised in that they have a controlled morphology and size and a high SPR absorbance intensity in a narrow wavelength range.

IPC Classes  ?

• B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
• B22F 9/24 - Making metallic powder or suspensions thereof; Apparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
• B23K 26/12 - Working by laser beam, e.g. welding, cutting or boring in a special environment or atmosphere, e.g. in an enclosure
• B22F 1/02 - Special treatment of metallic powder, e.g. to facilitate working, to improve properties; Metallic powders per se, e.g. mixtures of particles of different composition comprising coating of the powder

Abstract

The invention is characterized in that it comprises a plurality of impedances (R2, C3, R4, R5) and at least one operational amplifier (51, 52), and means (53) for connecting a resistive sensor (Rs) to the electronic circuit (50) such that, once the resistive sensor has been connected to the electronic circuit, a resulting electronic circuit is obtained that consists of the electronic circuit and the resistive sensor connected thereto, the input impedance (Zinp) of which corresponds to that of a variable capacitance as a function of the resistive sensor (Rs). A capacitative input impedance that can vary as a function of a sensor is obtained.

IPC Classes  ?

• H03H 11/44 - Negative impedance converters
• H03H 11/10 - Frequency selective two-port networks using negative impedance converters
• H03B 5/08 - Generation of oscillations using amplifier with regenerative feedback from output to input with frequency-determining element comprising lumped inductance and capacitance

Abstract

Use of the PEDF factor to induce cell regeneration. The present invention refers to the use of the molecule PEDF for the manufacture of medicines to activate processes included in the group of regenerative processes, such as skin regeneration, wound healing, cell therapy for cardiac, neural, or hematopoietic regeneration. It also refers to the manufacture/use of pharmaceutical compounds that contain an efficient quantity of the PEDF factor for stem cell self-renewal.

IPC Classes  ?

• A61K 38/18 - Growth factors; Growth regulators
• A61P 35/00 - Antineoplastic agents
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like