Abrégé

The present invention relates to ester compounds comprising a 2-(1,5-dimethyl-4- methylenecyclopent-2-en-1-yl)ethyl core and to a composition that comprises said compounds and attracts the species Pseudococcus longispinus. The present invention also refers to an attractant device for Pseudococcus longispinus comprising said compounds or said composition, preferably incorporated in a carrier, to a method for control and/or monitoring of the populations of insects of the species Pseudococcus longispinus and to the use of the compound, composition or device of the invention for control and/or monitoring of the pest. Finally, the present invention provides a method for preparing the ester compounds of the invention.

Classes IPC  ?

• C07C 69/14 - Esters d'acide acétique de composés monohydroxylés
• C07C 69/24 - Esters d'acides acycliques monocarboxyliques saturés dont le groupe carboxyle est lié à un atome de carbone acyclique ou à l'hydrogène avec au moins trois atomes de carbone dans la partie acide estérifiés par des composés monohydroxylés
• A01P 17/00 - Répulsifs des animaux nuisibles
• A01N 1/00 - Conservation de corps humains ou animaux, ou de parties de ceux-ci

Abrégé

The device for storing and/or converting energy (1) comprises one or more spacers (2) defining two sides; and electrodes (3) in contact with one or both sides of the spacer (2), each electrode (3) comprising an ink including at least one conductive additive. The method comprises the following steps: preparing an ink, the ink comprising at least one conductive additive; and forming electrodes (3) with the ink, the electrodes (3) being in contact with one or both sides of one or more spacers (2). It allows the separator itself to act as a collector at the same time, providing a solution to the problem of oxidation of metal collectors, among others.

Classes IPC  ?

• H01G 11/52 - Séparateurs
• H01G 11/02 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants utilisant des combinaisons de réactions de réduction et d'oxydation, p.ex. dispositifs redox ou solion
• H01G 11/06 - Condensateurs hybrides avec une des électrodes permettant de doper les ions de façon réversible, p.ex. condensateurs lithium-ion
• H01G 11/38 - Pâtes ou mélanges de carbone; Liants ou additifs
• H01G 11/50 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrodes caractérisées par leur matériau spécialement adaptées aux condensateurs lithium-ion, p.ex. pour doper le lithium ou pour intercalation
• H01G 11/86 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants spécialement adaptés pour les électrodes
• H01M 4/04 - Procédés de fabrication en général
• H01M 4/139 - Procédés de fabrication
• H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p.ex. liants, charges
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
• H01M 10/058 - Structure ou fabrication
• H01M 50/46 - Séparateurs, membranes ou diaphragmes caractérisés par leur combinaison avec des électrodes
• H01G 11/36 - Nanostructures, p.ex. nanofibres, nanotubes ou fullerènes
• H01G 11/84 - Procédés de fabrication de condensateurs hybrides ou EDL ou de leurs composants
• H01M 50/417 - Polyoléfines
• H01M 50/429 - Polymères naturels
• C09D 11/52 - Encres conductrices de l’électricité

Produits et services

Educational software and Educational mobile applications; Interactive electronic publications; E-books; Education software; All the aforesaid goods for developing and training emotional skills. Education, entertainment and sports; Education and instruction; Publishing, reporting, and writing of texts; Education and training consultancy; Arranging and conducting of conferences, congresses and symposiums; Organisation of congresses and conferences for cultural and educational purposes; Educational examination; Publication of newspapers, periodicals, catalogs and brochures; Multimedia publishing of books; Publication and edition of books; Publishing of instructional books; Online publication of electronic books and journals; Postgraduate training courses; Educational research; Publication of instructional literature; Educational seminars; Development of educational materials; Developing educational manuals; Workshops for educational purposes; All the aforesaid services for developing and training emotional skills and wellness in infants, adolescents and young children. Science and technology services; IT services; Design, development and programming of computer software; Design and development of software in the field of mobile applications; Programming of educational software; Hosting multimedia educational content; Research and development of educational applications and games via mobile apps for developing and training emotional skills; Research and development of educational applications and games via technological platforms for developing and training emotional skills.

Abrégé

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p.ex. nucléosides, nucléotides  contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/09 - Ethers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61K 31/23 - Esters, p.ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p.ex. pravastatine d'acides ayant un groupe carboxyle lié à une chaîne d'au moins sept atomes de carbone
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

An apparatus (1) for treating a cancerous target site is provided. The apparatus comprises an electromagnetic emitter (10) comprising one or more electrodes with an electrically insulating coating for preventing electrical contact between the electrodes and the target site. The electromagnetic emitter (10) is configured to provide a tumour treating field at a target site (30) via the one or more electrodes, the tumour treating field being non-ionizing alternating electromagnetic field having a frequency of between 10 kHz to 300 kHz; and further having a magnetic flux density of between 0.1pT and 1mT. The apparatus further comprises a heat source (20) configured to provide heating at the target site to cause hyperthermia at the target site. The apparatus is configured to apply the non-ionizing alternating electromagnetic field and the heating independently. The apparatus comprises an electronic controller for electronically controlling the electromagnetic emitter and the heat source.

Classes IPC  ?

• A61N 2/00 - Magnétothérapie
• A61N 1/40 - Application de champs électriques par couplage inductif ou capacitif
• A61N 7/02 - Hyperthermie localisée par ultrasons

Abrégé

The present invention relates to a layered double hydroxide comprising at least one divalent cation AII or alternatively LiI, at least one trivalent cation BIII selected from the group consisting of VIII, CoIII, CrIII, MnIII, FeIII, GaIII and lanthanides. The present invention also relates to a process for the synthesis of said layered double hydroxide and uses thereof.

Classes IPC  ?

• C01G 53/00 - Composés du nickel

Abrégé

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.

Classes IPC  ?

• A61K 31/7076 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p.ex. nucléosides, nucléotides  contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle contenant des pyrimidines condensées ou non-condensées contenant des purines, p.ex. adénosine, acide adénylique
• A61K 31/05 - Phénols
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p.ex. indolizine, bêta-carboline

Abrégé

The present invention relates to a compound 1 or 2 or a composition comprising same. The invention also relates to a method for obtaining compound 1 or 2, and to the use of the compounds to detect GHB in beverages. The invention also includes a device or kit for used to detect GHB in beverages.

Classes IPC  ?

• C07C 335/16 - Dérivés de thiourée ayant des atomes d'azote de groupes thiourée liés à des atomes de carbone de cycles aromatiques à six chaînons d'un squelette carboné
• C07C 59/01 - Composés saturés ne comportant qu'un groupe carboxyle et contenant des groupes hydroxyle ou O-métal
• G01N 21/78 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique produisant un changement de couleur
• G01N 33/14 - Boissons

Abrégé

A method for the diagnosis of systemic lupus erythematosus (SLE) based on an interfacial process of antigen-antibody molecular recognition, specifically between anti-Ro52 and Ro52 protein, in a piezoelectric resonator, for application in the diagnosis of autoimmune diseases such as SLE.

Classes IPC  ?

• G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet
• G01N 33/564 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour complexes immunologiques préexistants ou maladies auto-immunes
• G01N 33/543 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques

Abrégé

The titanium(IV) and iron(III) MOF solid MUV-17 (TiFe2), has the general formula (1): [TiIVFeIII2(O)(L)2(X)3]S, where X is each equal or different selected from: O2-, OH-, H2O, F-, Cl-, Br-, I-, NO3-, ClO4-, BF4-, SCN-, OH-, CH3COO-, C5H7O2-, SO42- and CO32-, L is a 5 tricarboxylic ligand and S is at least one molecule of a polar solvent selected from the group consisting of N,N'-dimethylformamide, N, N'-diethylformamide, N,N'-dimethylacetamide, N-methyl-2-pyrrolidone, methanol, ethanol, isopropanol, n-propanol, water and mixtures thereof. The titanium(IV) and iron(III) MOF solid has long-term catalytic activity for the degradation of toxic compounds. The method for obtaining them comprises 10 dissolving the components under anaerobic conditions. The invention also relates to the use of the titanium(IV) and iron(III) MOF solid as an additive with toxic compound detoxifying properties.

Classes IPC  ?

• C07F 7/28 - Composés du titane
• B01J 21/06 - Silicium, titane, zirconium ou hafnium; Leurs oxydes ou hydroxydes
• C07C 63/307 - Acides tricarboxyliques monocycliques
• C07F 15/02 - Composés du fer

Abrégé

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside, pterostilbene and a phosphodiesterase (PDE) inhibitor, including a PDE4 inhibitor such as ibudilast, and also including a thiol/cysteine donor, such as acetylcysteine.

Classes IPC  ?

• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p.ex. nucléosides, nucléotides  contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/09 - Ethers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61K 31/198 - Alpha-amino-acides, p.ex. alanine, acide édétique (EDTA)
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p.ex. indolizine, bêta-carboline
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux

Abrégé

The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

filtering the mixture treated in the reactor, in at least one filtration tank through the gasified membrane under conditions such that the relationship between the biogas recirculated per square meter of membrane, and time unit, and the wastewater filtered—SGDp—is the minimum value allowed by the solid concentration in a treatment plant.

Classes IPC  ?

• C02F 3/28 - Procédés de digestion anaérobies
• C02F 3/00 - Traitement biologique de l'eau, des eaux résiduaires ou des eaux d'égout

Abrégé

The present invention relates to a method for the diagnosis of systemic lupus erythematosus (SLE), which is a diagnostic method based on an interfacial process of antigen-antibody molecular recognition, specifically between anti-Ro52 and Ro52 protein, in a piezoelectric resonator, for use in the diagnosis of autoimmune diseases such as SLE.

Classes IPC  ?

• G01G 3/13 - Appareils de pesée caractérisés par l'utilisation d'organes déformables par élasticité, p.ex. balances à ressort dans lesquels l'élément de pesée est constitué par un corps solide soumis à une pression ou une traction pendant la pesée le corps solide présentant des propriétés piézo-électriques ou piézo-résistives
• G01N 29/036 - Analyse de fluides en mesurant la fréquence ou la résonance des ondes acoustiques
• G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet

Abrégé

Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.

Classes IPC  ?

• A61K 31/05 - Phénols
• A61K 31/09 - Ethers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p.ex. nucléosides, nucléotides  contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
• A61K 31/7052 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p.ex. nucléosides, nucléotides 
• C07C 15/52 - Hydrocarbures cycliques ne contenant que des cycles aromatiques à six chaînons en tant que partie cyclique substitués par des radicaux hydrocarbonés non saturés polycycliques non condensés contenant un groupe de formule
• C07C 39/205 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques ne contenant que des cycles aromatiques à six chaînons dans la partie cyclique, avec une insaturation autre que celle des cycles
• C07H 19/02 - Composés contenant un hétérocycle partageant un hétéro-atome du cycle avec un radical saccharide; Nucléosides; Mononucléotides; Leurs anhydro-dérivés partageant un azote
• C07H 19/048 - Radicaux pyridine

Abrégé

R. solanacearum in river courses and irrigation water, as well as in a method for preventing and/or controlling the wilt produced by the bacteria, in which at least one of the bacteriophages, or combinations thereof, are delivered to the plants and/or the soil in the irrigation water.

Classes IPC  ?

• C12N 7/00 - Virus, p.ex. bactériophages; Compositions les contenant; Leur préparation ou purification
• A01N 63/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des micro-organismes, des virus, des champignons microscopiques, des animaux ou des substances produites par, ou obtenues à partir d
• A01M 7/00 - Adaptations ou aménagements particuliers des appareils de pulvérisation de liquides aux fins couvertes dans la présente sous-classe
• A01G 25/02 - Systèmes d'arrosage placés au-dessus du sol qui utilisent des canalisations perforées ou des canalisations avec accessoires pour la distribution, p.ex. pour l'irrigation goutte à goutte
• A01G 25/06 - Agencements pour l'arrosage utilisant des conduits perforés placés dans le sol
• A01G 27/00 - Dispositifs automatiques d'arrosage, p.ex. pour pots de fleurs
• A01G 31/00 - Culture hors-sol, p.ex. hydroponie

Abrégé

The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof, a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.

Classes IPC  ?

• A61K 31/09 - Ethers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61P 35/00 - Agents anticancéreux
• A61K 31/225 - Acides polycarboxyliques
• A61K 31/277 - Nitriles; Isonitriles ayant un cycle, p.ex. vérapamil
• A61K 31/42 - Oxazoles
• A61K 31/4412 - Pyridines non condensées; Leurs dérivés hydrogénés ayant des groupes oxo liés directement à l'hétérocycle
• A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p.ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p.ex. clozapine, dilazèpe
• A61K 31/635 - Composés contenant des groupes para-N-benzènesulfonyl-N-, p.ex. sulfanilamide, p-nitrobenzènesulfonohydrazide contenant un hétérocycle, p.ex. sulfadiazine

Abrégé

The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present invention refers to an anaerobic process with filtration procedure for wastewater treatment at room temperature, that comprises: - continuously feeding at least one anaerobic reactor, with previously sieved wastewater and feeding biodegradable organic waste - BOW - also previously sieved, said reactor being coupled to at least one gasified filtration membrane, with recirculation of biogas from the reactor, - carrying out the anaerobic digestion of the organic fraction contained in the mixture of wastewater and the BOW, in the reactor, obtaining a treated mixture and - filtering the mixture treated in the reactor, in at least one filtration tank through the gasified membrane under conditions such that the relationship between the biogas recirculated per square meter of membrane, and time unit, and the wastewater filtered - - SGDp - is the minimum value allowed by the solid concentration in a treatment plant.

Classes IPC  ?

• C02F 3/28 - Procédés de digestion anaérobies

Abrégé

The invention relates to a device comprising a multi-mode waveguide structure with a number N of single-mode inlet and outlet waveguides (10, 20) to allow the propagation of an optical series injected into the optical multi-mode interference coupler device (1), or MMI coupler, wherein a series of multiple images of the injected optical signal is formed in an interior area thereof. According to the invention, the MMI coupler (1) comprises a unit (15) for generating a travelling surface acoustic wave (SAW) that hits the interior area of the MMI coupler (1) to modulate with an opposite phase the effective refraction index of the multiple images formed, the images being separated by a distance determined according to the expression: λSAW/2+nλSAW.

Classes IPC  ?

• G02B 6/26 - Moyens de couplage optique

Abrégé

The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof,a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.

Classes IPC  ?

• A61K 31/09 - Ethers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention relates to a combination comprising pterostilbeneor pterostilbene phosphate or a pharmaceutically acceptable salt thereof,a glutathione depleting agent and a cancer chemotherapeutic agent. The invention also relates to the medical use of this combination, in particular for the treatment and/or prevention of cancer.

Classes IPC  ?

• A61K 31/09 - Ethers ou acétals ayant une liaison éther à un carbone cyclique d'un noyau aromatique ayant plusieurs liaisons éther
• A61P 35/00 - Agents anticancéreux

Abrégé

The invention relates to a method for the prevention and/or the biological control of wilt caused by Ralstonia solanacearum, via the use of bacteriophages suitable for this purpose, and to the structural characterisation, genome sequence and activity of three specific lytic bacteriophages of R. solanacearum. It relates to podovirus which, between 4º C and 30º C, presents an elevated stability in an aqueous medium in the absence of a host. As a result of the high level of stability, lytic activity, elevated specificity towards R. solanacearum and the absence of activity against the microbiota associated with the plants to be protected, the invention proposes the use thereof for the biological control of R. solanacearum in river courses and irrigation water, as well as a method for preventing and/or controlling the wilt produced by said bacteria, in which at least one of said bacteriophages, or combinations thereof, are delivered to the plants and/or the soil in the irrigation water.

Classes IPC  ?

• C12N 7/00 - Virus, p.ex. bactériophages; Compositions les contenant; Leur préparation ou purification

Abrégé

The invention relates to a lichen extract and to the use of same for improving the recovery of microorganisms associated with lichens. In this way, the invention relates to a method for improving or optimising the isolation and/or culture of microorganisms associated with lichens, which comprises the processing of lichen thalli which are washed, or washed and chopped, in a culture medium comprising the lichen extract of a population of the species of lichen from which the microorganisms are to be isolated. The invention also relates to the method for obtaining the lichen extract and to the composition comprising the lichen extract thus obtained.

Classes IPC  ?

• A01H 15/00 - Champignons; Lichens
• C12N 1/00 - Micro-organismes, p.ex. protozoaires; Compositions les contenant; Procédés de culture ou de conservation de micro-organismes, ou de compositions les contenant; Procédés de préparation ou d'isolement d'une composition contenant un micro-organisme; Leurs milieux de culture

Abrégé

Compound for treatment of myotonic dystrophy type The present invention relates to a compound, or a salt thereof, and a pharmaceutical composition comprising said compound, or a salt thereof, for use in the prevention and/or treatment of myotonic dystrophy type 1 in a patient, in particular by reducing the levels of autophagy and apoptosis that are elevated in myotonic muscular dystrophy type 1.

Classes IPC  ?

• A61K 31/198 - Alpha-amino-acides, p.ex. alanine, acide édétique (EDTA)
• A61K 31/4439 - Pyridines non condensées; Leurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à cinq chaînons avec l'azote comme hétéro-atome du cycle, p.ex. oméprazole
• A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
• A61K 31/4745 - Quinoléines; Isoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. phénanthrolines
• A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire

Abrégé

The invention relates to a device for attaching a macroporous material for regenerating articular cartilage to the subchondral bone, characterised in that it includes: a) a sponge which comprises a biocompatible macroporous material that is suitable for regenerating articular cartilage, b) an attachment system suitable for attaching the device to the subchondral bone, and c) a supporting part suitable for connecting the sponge to the attachment system. The device according to the invention enables the regeneration of articular cartilage, providing a good system for attachment to the chondral bone, while avoiding damage to the sponge material when attaching the device to the bone.

Classes IPC  ?

• A61B 17/68 - Dispositifs de fixation interne
• A61F 2/30 - Articulations
• A61L 27/56 - Matériaux poreux ou cellulaires
• A61L 27/58 - Matériaux au moins partiellement résorbables par le corps

Abrégé

Use of the phenantrenic alkaloids seconeolitsine and N-methyl-seconeolitsine for the manufacture of medicaments. More particularly the use is described of the said compounds for the manufacture of antibiotics, especially for the treatment of diseases caused by Gram-positive bacteria, preferably Streptococcus pneumoniae or Staphylococcus aureus. The application thereof is of special relevance for producing medicaments for the treatment of pneumonia.

Classes IPC  ?

• C07D 317/70 - Composés hétérocycliques contenant des cycles à cinq chaînons comportant deux atomes d'oxygène comme uniques hétéro-atomes du cycle comportant les hétéro-atomes en positions 1, 3 condensés en ortho ou en péri avec des carbocycles ou avec des systèmes carbocycliques condensés avec des systèmes cycliques contenant au moins deux cycles déterminants
• A61K 31/36 - Composés contenant des groupes méthylènedioxyphényle, p.ex. sésamine
• A61P 31/04 - Agents antibactériens

Abrégé

The present invention relates to a method and kits for determining the concentration of anionic surfactants in water or aqueous media by promoting the formation of foam attributable to the same and as a function of the period for disappearance of the foam ring formed on the surface of the water or aqueous medium. For this purpose there is added to a sample of water or aqueous medium a promoter of production of foam attributable to the anionic surfactant to which there has previously been added a buffer to maintain the pH during the test period at a value ≤ 6.

Classes IPC  ?

• G01N 33/18 - Eau
• G01N 31/22 - Utilisation des réactifs chimiques
• G01N 21/75 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé
• G01N 13/00 - Recherche des effets de surface ou de couche limite, p.ex. pouvoir mouillant; Recherche des effets de diffusion; Analyse des matériaux en déterminant les effets superficiels, limites ou de diffusion

Abrégé

The invention relates to the compression of colour images, based on non-linear perceptual representations and machine learning. More specifically, the invention relates to a method for the compression of colour images, comprising the following steps: (1) expressing the coefficients of a local space/frequency representation of the opposing chromatic and achromatic channels in units of perceptual contrast; (2) applying a non-linear transform with divisive normalisation to each channel, such that they include relationships between the coefficients of the achromatic and chromatic contrast channels; and (3) using statistical learning algorithms to select the relevant data from the non-linearly normalised channels. Psychophysical and numerical experiments have been conducted in order to estimate and validate the parameters of the divisive normalisation and contrast transforms. In addition, the above method has been compared experimentally with a JPEG implementation. In both cases, 16x16 DCT blocks were used and, in each case, comparable values were used for the frequency-dependent and chromatic transform parameters. Under these conditions, the experimental results provide an average compression gain of 50% in relation to JPEG for different distortion measurements (RMSE, SSIM and S-CIELab) in the realistic commercial range of [1, 2.2] bits/pix. The invention also relates to the apparatus and code used to implement said method.

Classes IPC  ?

• H04N 7/30 - comportant un codage par transformation (H04N 7/50 a priorité;calculateurs numériques pour la réalisation d'opérations mathématiques complexes, p.ex. transformations d'espace, G06F 17/14)
• H03M 7/30 - Compression; Expansion; Elimination de données inutiles, p.ex. réduction de redondance
• G06T 9/00 - Codage d'image
• H04N 7/32 - comportant un codage par prédiction (H04N 7/48, H04N 7/50 ont priorité);;
• H04N 7/34 - utilisant la prédiction spatiale

Abrégé

The invention relates to homo and heterometallic soluble coordination polymers containing an oxalate ligand and to a method for obtaining spinels from same. The homo and heterometallic coordination polymers, which contain at least one oxalate ligand, are characterised in that they also contain at least one organic molecule capable of stabilising expanded metal complex structures through the formation of supramolecular interactions such that the polymer is substantially soluble in water and insoluble in organic solvents. Said polymers, when in the solid state, can generate spinel-type metal oxides or other mixed oxides following a thermal oxidation treatment including steps comprising: the preparation of an alcoholic solution of a metal complex containing at least one oxalate ligand and a metal salt, the precipitation of the metal complex and the metal salt with a cryptand-type molecule through the formation of a coordination polymer that is soluble in water and insoluble in organic solvents, the separation of the precipitate obtained in the previous step, and the heating of same in an oxidant atmosphere to a temperature of at least 350ºC until the spinel or mixed oxide has formed.

Classes IPC  ?

• C08G 79/00 - Composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant des atomes autres que le silicium, le soufre, l'azote, l'oxygène et le carbone, avec ou sans ces derniers éléments
• C01B 13/32 - Méthodes de préparation des oxydes ou hydroxydes en général par oxydation ou hydrolyse d'éléments ou de composés à l'état liquide ou solide

Abrégé

The invention relates to plasmonic nanocomposites based on polymer and metal nanoparticles for lithographic use. More specifically, the invention relates to a method for the synthesis of a nanocomposite formed by a polymer with noble metal nanoparticles embedded therein. The method is characterised in that the noble metal reduction reaction, which produces the nanoparticles, and the polymer chain cross-linking, which forms the polymer matrix, occur simultaneously as a result of the heating generated during the irradiation process, thereby enabling the generation of nanostructures using a standard lithographic process. The invention also relates to the resulting nanocomposites and to the uses thereof in different technical fields.

Classes IPC  ?

• G03F 7/00 - Production par voie photomécanique, p.ex. photolithographique, de surfaces texturées, p.ex. surfaces imprimées; Matériaux à cet effet, p.ex. comportant des photoréserves; Appareillages spécialement adaptés à cet effet
• B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles

Abrégé

The invention relates to a method for the production and purification of PEDF molecules and mutated and/or truncated versions of said molecule in a yeast expression system. The invention also relates to the protection of the PEDF molecules directly obtained and to the use of same in the preparation of pharmaceutical compositions. The method includes the following steps in which: the PEDF cDNA is obtained at least from cells of the retinal pigmented epithelium, mutant and/or truncated versions are obtained, the structures are cloned into a yeast expression vector, the yeast clones are transformed and selected, the yeast culture medium is inoculated with the clones obtained, the intact or truncated PEDF factor is induced in the yeast, the cells are eliminated from the culture by means of centrifugation, the culture medium containing the intact and/or truncated PEDF factor is changed, and said PEDF factor is purified and isolated.

Classes IPC  ?

• C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
• C07K 14/81 - Inhibiteurs de protéase
• A61K 38/57 - Inhibiteurs de protéases  provenant d'humains
• A61P 27/02 - Agents ophtalmiques

Abrégé

The invention relates to a method for the synthesis of inert metal nanoparticles. More specifically, the invention relates to a method for obtaining stable colloids of inert metal nanoparticles in a single step comprising the laser ablation of a solid target submerged in a liquid medium containing metal salts. The invention also relates to the nanoparticles synthesised using the aforementioned method and characterised in that they have a controlled morphology and size and a high SPR absorbance intensity in a narrow wavelength range.

Classes IPC  ?

• B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
• B22F 9/24 - Fabrication des poudres métalliques ou de leurs suspensions; Appareils ou dispositifs spécialement adaptés à cet effet par un procédé chimique avec réduction de mélanges métalliques à partir de mélanges métalliques liquides, p.ex. de solutions
• B23K 26/12 - Travail par rayon laser, p.ex. soudage, découpage ou perçage  sous atmosphère particulière, p.ex. dans une enceinte
• B22F 1/02 - Traitement particulier des poudres métalliques, p.ex. en vue de faciliter leur mise en œuvre, d'améliorer leurs propriétés; Poudres métalliques en soi, p.ex. mélanges de particules de compositions différentes comportant un enrobage des particules

Abrégé

The invention is characterized in that it comprises a plurality of impedances (R2, C3, R4, R5) and at least one operational amplifier (51, 52), and means (53) for connecting a resistive sensor (Rs) to the electronic circuit (50) such that, once the resistive sensor has been connected to the electronic circuit, a resulting electronic circuit is obtained that consists of the electronic circuit and the resistive sensor connected thereto, the input impedance (Zinp) of which corresponds to that of a variable capacitance as a function of the resistive sensor (Rs). A capacitative input impedance that can vary as a function of a sensor is obtained.

Classes IPC  ?

• H03H 11/44 - Convertisseurs à impédance négative
• H03H 11/10 - Réseaux sélectifs en fréquence à deux accès utilisant des convertisseurs à impédance négative
• H03B 5/08 - Eléments déterminant la fréquence comportant des inductances ou des capacités localisées

Abrégé

Use of the PEDF factor to induce cell regeneration. The present invention refers to the use of the molecule PEDF for the manufacture of medicines to activate processes included in the group of regenerative processes, such as skin regeneration, wound healing, cell therapy for cardiac, neural, or hematopoietic regeneration. It also refers to the manufacture/use of pharmaceutical compounds that contain an efficient quantity of the PEDF factor for stem cell self-renewal.

Classes IPC  ?

• A61K 38/18 - Facteurs de croissance; Régulateurs de croissance
• A61P 35/00 - Agents anticancéreux
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires