The University of Tokyo

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1.

AIR CONDITIONING SYSTEM AND AIR CONDITIONING METHOD

      
Application Number 18858989
Status Pending
Filing Date 2023-03-07
First Publication Date 2025-03-27
Owner
  • The University of Tokyo (Japan)
  • CHIYODA CORPORATION (Japan)
  • SHIMIZU CORPORATION (Japan)
Inventor
  • Ebe, Hiroji
  • Sugiyama, Masakazu
  • Matsumoto, Jun
  • Takeda, Dai
  • Oba, Ittetsu
  • Hashimoto, Shinya
  • Fuse, Yukinori
  • Sumikura, Mitsuhiro
  • Arai, Yoshito

Abstract

An air conditioning system (1) includes a carbon dioxide separation device (20) configured to separate some or all of carbon dioxide from air that contains carbon dioxide, an electrolytic reduction device (30) configured to generate a hydrocarbon and oxygen using the separated carbon dioxide as a raw material, and an oxygen supply amount control device (40) configured to supply some or all of the oxygen generated by the electrolytic reduction device (30) to a space to be processed (10).

IPC Classes  ?

  • F24F 8/60 - Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by adding oxygen
  • C25B 1/02 - Hydrogen or oxygen
  • C25B 3/01 - Products
  • C25B 3/26 - Reduction of carbon dioxide
  • C25B 15/02 - Process control or regulation
  • C25B 15/08 - Supplying or removing reactants or electrolytesRegeneration of electrolytes
  • F24F 8/10 - Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering

2.

METHOD FOR DIAGNOSING COLORECTAL CANCER AND METHOD FOR EVALUATING EFFECT OF ADJUVANT CHEMOTHERAPHY APPLIED TO COLORECTAL CANCER PATIENT

      
Application Number JP2024033732
Publication Number 2025/063294
Status In Force
Filing Date 2024-09-20
Publication Date 2025-03-27
Owner
  • KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • JAPANESE FOUNDATION FOR CANCER RESEARCH (Japan)
  • NAGASAKI UNIVERSITY (Japan)
Inventor
  • Mimori, Koshi
  • Niida, Atsushi
  • Nagayama, Satoshi
  • Uno, Naoki

Abstract

The present invention provides a method for detecting colorectal cancer in a subject, said method comprising a step for determining the methylation state of at least one of the FGD5 gene and the GPC6 gene in the subject.

IPC Classes  ?

  • C12Q 1/686 - Polymerase chain reaction [PCR]
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

3.

OXYETHYLENE CHAIN-CONTAINING POLYMER

      
Application Number 18861997
Status Pending
Filing Date 2023-05-19
First Publication Date 2025-03-27
Owner
  • MARUZEN PETROCHEMICAL CO., LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Nishiura, Takao
  • Miyata, Kanjiro
  • Fujiura, Kento

Abstract

[Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity. [Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity. [Solution] An oxyethylene chain-containing polymer according to the present invention is represented by the following general formula (1): [Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity. [Solution] An oxyethylene chain-containing polymer according to the present invention is represented by the following general formula (1): [Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity. [Solution] An oxyethylene chain-containing polymer according to the present invention is represented by the following general formula (1): (wherein, in the general formula (1), R1 is —(CH2)p—SH, —(CH2)p—N3, (CH2)p—NH2, or —(CH2)p—COOH, and p is an integer of 1 to 5; R2 to R4 are each independently hydrogen or a C1-10 alkyl group; R5 is a C1-10 alkyl group; R6 is hydrogen or a C1-5 alkyl group; R7 is a C1-10 alkyl group; n is an integer of 5 to 1000; m is an integer of 1 to 10; and q is an integer of 0 to 5).

IPC Classes  ?

  • C08F 8/34 - Introducing sulfur atoms or sulfur-containing groups
  • C08F 8/06 - Oxidation
  • C08F 8/30 - Introducing nitrogen atoms or nitrogen-containing groups
  • C08F 116/20 - Monomers containing three or more carbon atoms in the unsaturated aliphatic radical
  • C08F 216/20 - Monomers containing three or more carbon atoms in the unsaturated aliphatic radical

4.

INFORMATION PROCESSING SYSTEM, INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND PROGRAM

      
Application Number 18728711
Status Pending
Filing Date 2023-01-12
First Publication Date 2025-03-27
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor Yokoyama, Kazuaki

Abstract

The present invention addresses the problem of improving user-friendliness and efficiency in analyzing the extent of possibility that there is a mutation that affects the occurrence or progression of disease. A training unit of an information processing system including an analysis device for selecting cancer driver mutations of a test subject uses a plurality of training information sets to execute machine learning by using, as training information sets regarding a prescribed nucleic acid, information indicating known sequence mutations carrying adverse risks, and at least some clinically significant information regarding mutations from among a public database, a human gene polymorphism database, a database pertaining to drug-gene interactions and genome resources for new drug development, and a drug response database. When a prescribed sequence mutation is inputted, the training unit generates or updates an AI model for outputting a ranking of the degree of possibility that said sequence mutation is a target sequence mutation. A rescue filter unit reclassifies, to a higher rank, sequence mutations for which the degree of possibility output by the model is greater than or equal to a certain value. The abovementioned problem is solved through this configuration.

IPC Classes  ?

  • G16B 20/20 - Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
  • G16B 30/00 - ICT specially adapted for sequence analysis involving nucleotides or amino acids

5.

UBIQUITIN HIGH AFFINITY CYCLIC PEPTIDES AND METHODS OF USE THEREOF

      
Application Number 18969949
Status Pending
Filing Date 2024-12-05
First Publication Date 2025-03-27
Owner
  • TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (Israel)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Brik, Ashraf
  • Kamnesky, Guy
  • Suga, Hiroaki
  • Huang, Yichao
  • Rogers, Joseph

Abstract

The present invention provides cyclic peptides, as well as methods of using the same, such as for ameliorating or treating a K63Ub-related disease in a subject in need thereof.

IPC Classes  ?

  • A61K 38/12 - Cyclic peptides
  • C07K 7/64 - Cyclic peptides containing only normal peptide links

6.

CATALYST FOR OLEFIN POLYMERIZATION AND PRODUCTION METHOD FOR OLEFIN-BASED POLYMER

      
Application Number 18715542
Status Pending
Filing Date 2022-11-18
First Publication Date 2025-03-27
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • RESONAC CORPORATION (Japan)
  • JAPAN POLYETHYLENE CORPORATION (Japan)
Inventor
  • Nozaki, Kyoko
  • Seidel, Falk William
  • Akita, Shumpei
  • Kimura, Kento
  • Kuroda, Junichi
  • Uematsu, Masahiro
  • Sakuragi, Tsutomu

Abstract

Provided are a catalyst and a method that enable the production of an olefin-based polymer, which has a polar group and is usable for various applications, at high catalytic activity. A metal complex shown in general formula (C1) (in the formula, M represents a palladium atom or a nickel atom, X represents a phosphorus atom (P), R5-R9 are as set forth in the claims, L represents an electron donating ligand, and q is 0, ½, 1, or 2) is used as a catalyst for polymerization of an olefin having a polar group.

IPC Classes  ?

  • C08F 4/80 - MetalsMetal hydridesMetallo-organic compoundsUse thereof as catalyst precursors selected from metals not provided for in group selected from iron group metals or platinum group metals
  • C08F 110/02 - Ethene
  • C08F 210/02 - Ethene

7.

HUMANIZED ANTIBODY CAPABLE OF BINDING TO HEG1 PROTEIN

      
Application Number 18574969
Status Pending
Filing Date 2022-06-30
First Publication Date 2025-03-20
Owner
  • Kanagawa Prefectural Hospital Organization (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Tsuji, Shoutaro
  • Imai, Kohzoh

Abstract

The present invention provides a humanized antibody or an antigen-binding fragment thereof that binds to a HEG1 protein, in which the antibody is capable of binding to a human HEG1 protein expressed in mesothelioma cells.

IPC Classes  ?

  • C07K 16/30 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

8.

CRYOGENIC HEAT SWITCH, METHOD FOR MANUFACTURING CRYOGENIC HEAT SWITCH, AND CONTINUOUS NUCLEAR ADIABATIC DEMAGNETIZATION REFRIGERATION UNIT

      
Application Number JP2024030036
Publication Number 2025/057698
Status In Force
Filing Date 2024-08-23
Publication Date 2025-03-20
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Fukuyama, Hiroshi
  • Toda, Ryo
  • Takimoto, Shohei
  • Murakawa, Satoshi

Abstract

One aspect of the present invention provides a cryogenic heat switch. The cryogenic heat switch includes at least one switching portion, a first heat conducting portion, a second heat conducting portion, and a restricting portion. The at least one switching portion is configured to switch between a superconducting state and a normal conducting state upon application of a magnetic field equal to or greater than a critical magnetic field. The at least one switching portion in the normal conducting state has a higher thermal conductivity than the at least one switching unit in the superconducting state. The first heat conducting portion comprises a first base portion coupled to a first member and at least one first switching coupling portion. The at least one first switching coupling portion extends from the first base portion in a first direction and is coupled to a first end of the at least one switching portion. The at least one first switching coupling portion has a rigidity lower than that of the first base portion. The second heat conducting portion comprises a second base portion coupled to a second member and at least one second switching coupling portion. The at least one second switching coupling portion extends from the second base portion in a second direction and is coupled to a second end of the at least one switching portion. The at least one second switching coupling portion has a rigidity lower than that of the second base portion. The restricting portion is coupled to the first base portion and the second base portion without the at least one switching portion being interposed therebetween. The thermal conductivity of the restricting portion is lower than the thermal conductivity of the at least one switching portion in the superconducting state.

IPC Classes  ?

  • F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
  • H10N 60/30 - Devices switchable between superconducting and normal states

9.

NUCLEIC ACID APTAMER AND BONE REGENERATION INDUCING MATERIAL CONTAINING SAID NUCLEIC ACID APTAMER

      
Application Number JP2024032702
Publication Number 2025/058014
Status In Force
Filing Date 2024-09-12
Publication Date 2025-03-20
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • GELLYCLE CO., LTD. (Japan)
  • JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES (Japan)
Inventor
  • Sakai Takamasa
  • Fujisawa Ayano
  • Tei Yuichi
  • Kamata Hiroyuki
  • Yamamoto Eiichi
  • Fukui Chie
  • Haishima Yuuji
  • Nomura Yusuke

Abstract

[Problem] The problems addressed are to provide an NA-AP having excellent binding ability to BMP and to reduce the risk of ectopic ossification in bone regeneration treatment utilizing the same. [Solution] An NA-AP having specific binding ability to BMP and a bone regeneration inducing material of said NA-AP carried in a hydrogel were discovered.

IPC Classes  ?

  • C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • A61L 27/20 - Polysaccharides
  • A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
  • A61L 27/52 - Hydrogels or hydrocolloids
  • A61L 27/54 - Biologically active materials, e.g. therapeutic substances
  • A61P 19/00 - Drugs for skeletal disorders

10.

Method for Detecting Enzyme Activity and Fluorescent Probe Used in Said Method

      
Application Number 18843204
Status Pending
Filing Date 2023-03-02
First Publication Date 2025-03-20
Owner
  • The University of Tokyo (Japan)
  • RIKEN (Japan)
Inventor
  • Urano, Yasuteru
  • Komatsu, Toru
  • Sakamoto, Shingo
  • Ukegawa, Tatsuya
  • Watanabe, Rikiya

Abstract

An object of the present invention is to provide a method capable of detecting activity of an enzyme that strictly recognizes a substrate, such as acetylcholinesterase (AChE). There is provided a method for detecting activity of an enzyme in a biological sample using a microdevice, the method including a step of bringing the biological sample into contact with a substrate analog or a natural substrate, and a compound represented by General Formula (I) below or a salt thereof, wherein the substrate analog or the natural substrate generates a compound A having a thiol group (R—SH), a selenol group (R—SeH), or a poly sulfur atom (R—(S)n-H) (R is a hydrogen atom or an alkyl group, and n is 1 to 5) by a reaction with the enzyme, and fluorescence is observed or measured, the fluorescence being emitted or enhanced from a fluorescent product generated by the reaction of the compound represented by General Formula (I) or the salt thereof with the thiol group, the selenol group, or the poly sulfur atom.

IPC Classes  ?

  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • C07F 5/02 - Boron compounds
  • C07F 7/08 - Compounds having one or more C—Si linkages
  • C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
  • C12Q 1/46 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving esterase involving cholinesterase

11.

RAMAN SPECTROSCOPIC SIGNAL-ENHANCED NANOPARTICLES, RAMAN SPECTROSCOPIC SIGNAL-ENHANCED NANOPARTICLE DISPERSION, AND METHOD FOR PRODUCING RAMAN SPECTROSCOPIC SIGNAL-ENHANCED NANOPARTICLES

      
Application Number JP2024032893
Publication Number 2025/058063
Status In Force
Filing Date 2024-09-13
Publication Date 2025-03-20
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Goda, Keisuke
  • Xiao, Tinghui
  • Xingxing, Yu

Abstract

66]3-) and a hydrochloric acid solution of divalent copper ions (Cu2+ ions, copper (II) ions) is heated at 80°C for 24 hours to obtain a hydrochloric acid dispersion of the copper-substituted Prussian blue analog, and a step for drying the hydrochloric acid dispersion of the copper-substituted Prussian blue analog to obtain a powder of the copper-substituted Prussian blue analog, and have a particle size of 10-100 nm. In a state where a measurement target for Raman spectroscopy is adsorbed on the surface of the nanoparticles, Raman scattered light from the measurement target in light emitted from a light source is enhanced.

IPC Classes  ?

12.

CONTINUOUS LONG FIBER OF ALIPHATIC COPOLYMERIZED POLYESTER, AND METHOD FOR PRODUCING SAME

      
Application Number JP2024032913
Publication Number 2025/058065
Status In Force
Filing Date 2024-09-13
Publication Date 2025-03-20
Owner
  • ASAHI KASEI KABUSHIKI KAISHA (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Harano, Kodai
  • Yamaguchi, Saeko
  • Fujita, Keisuke
  • Hara, Yuichi
  • Kabe, Taizo
  • Iwata, Tadahisa

Abstract

The present invention addresses the problem of providing a continuous long fiber that comprises an aliphatic copolymerized polyester, has excellent storage stability, and can solve a problem of unwinding defects, as well as a method for producing said continuous long fiber. This continuous long fiber comprises an aliphatic copolymerized polyester, wherein the aliphatic copolymerized polyester includes 3-hydroxybutyrate as a first monomer unit and includes 4-hydroxybutyrate or 3-hydroxyvalerate as a second monomer unit, the ratio of the second monomer unit to all monomer units is 1 mol% to 9 mol% when the second monomer unit is the 4-hydroxybutyrate unit, and the ratio of the second monomer unit to all monomer units is 1 mol% to 7.6 mol% when the second monomer unit is 3-hydroxyvalerate.

IPC Classes  ?

  • D01F 6/84 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from copolycondensation products from copolyesters

13.

PULSED CURRENT DRIVE METHOD, PULSED CURRENT DRIVE STRUCTURE, CURRENT-DRIVEN MEMORY, STORAGE DEVICE, AND MEMORY CONTROL CIRCUIT

      
Application Number JP2024032498
Publication Number 2025/057970
Status In Force
Filing Date 2024-09-11
Publication Date 2025-03-20
Owner
  • SUMITOMO CHEMICAL COMPANY, LIMITED (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Okamoto Satoshi
  • Saitoh Eiji
  • Kikkawa Takashi
  • Chen Ziyan

Abstract

A pulsed current drive method according to the present invention involves applying a pulsed current to invert ferroelectric polarization generated by the order and imbalance of ions that have different valences.

IPC Classes  ?

  • H10B 53/30 - Ferroelectric RAM [FeRAM] devices comprising ferroelectric memory capacitors characterised by the memory core region
  • C04B 35/40 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on ferrites with rare earth oxide
  • G11C 11/22 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using electric elements using ferroelectric elements

14.

IMAGE PROCESSING ALGORITHM EVALUATING APPARATUS

      
Application Number 18562285
Status Pending
Filing Date 2022-05-18
First Publication Date 2025-03-13
Owner
  • MITSUBISHI HEAVY INDUSTRIES MACHINERY SYSTEMS, LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takakuwa, Yoshinao
  • Takahashi, Kunio
  • Iehara, Masato
  • Kamijo, Shunsuke
  • Shiotsuka, Daiki
  • Javanmardi, Ehsan

Abstract

An image processing algorithm evaluating apparatus includes: an image storage unit that stores a plurality of actual images captured from a vehicle; an image generating unit that acquires a target image, when receiving disturbance information representing a disturbance in the target image from among the plurality of actual images stored in the image storage unit, interprets the target image, and generates a composite image by manipulating the target image in such a manner that the disturbance is reflected to the target image based on the interpretation; and an image processing unit that evaluates performance of an image processing algorithm for determining a situation around the vehicle based on the generated composite image.

IPC Classes  ?

  • G06V 10/776 - ValidationPerformance evaluation
  • G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
  • G06V 20/56 - Context or environment of the image exterior to a vehicle by using sensors mounted on the vehicle

15.

VERTICAL DIODE AND METHOD FOR MANUFACTURING VERTICAL DIODE

      
Application Number JP2024031773
Publication Number 2025/053187
Status In Force
Filing Date 2024-09-04
Publication Date 2025-03-13
Owner
  • PI-CRYSTAL INC. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • NATIONAL INSTITUTE FOR MATERIALS SCIENCE (Japan)
Inventor
  • Makita, Tatsuyuki
  • Yamashita, Yu
  • Takeya, Junichi
  • Watanabe, Shunichiro
  • Osakabe, Nobutaka

Abstract

Provided is a vertical diode in which a first electrode, an organic semiconductor layer, and a second electrode are laminated adjacently in the stated order, wherein low-molecular hydrophobic ions are attached to the surface of the first electrode adjacent to the organic semiconductor layer.

IPC Classes  ?

16.

MAGNETIC SENSOR AND HETEROSTRUCTURE

      
Application Number JP2024031473
Publication Number 2025/053104
Status In Force
Filing Date 2024-09-02
Publication Date 2025-03-13
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Anh Le Duc
  • Hotta Tomoki
  • Tanaka Masaaki

Abstract

This magnetic sensor includes: a topological semimetal; a ferromagnetic body which is joined to the topological semimetal; and a measurement device for measuring a magnetic field on the basis of a voltage due to an odd-parity magnetoresistance effect generated in the topological semimetal.

IPC Classes  ?

17.

DATA PROCESSING ALGORITHM EVALUATION DEVICE

      
Application Number JP2024022169
Publication Number 2025/047062
Status In Force
Filing Date 2024-06-19
Publication Date 2025-03-06
Owner
  • MITSUBISHI HEAVY INDUSTRIES MACHINERY SYSTEMS, LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Shimizu, Hirokazu
  • Nishimori, Toshiaki
  • Nakao, Kenta
  • Kamijo, Shunsuke
  • Lee, Jinho

Abstract

The present invention comprises: a data storage unit that stores a plurality of radio wave distance measurement data items detected from a vehicle; a data generation unit that, when external disturbance information indicating an external disturbance to target data among the plurality of radio wave distance measurement data items stored in the storage unit is inputted, acquires and understands the target data, and generates synthesized data by working, on the basis of the understanding, the target data so that the external disturbance is reflected in the target data; and a data processing unit that evaluates, on the basis of the generated synthesized data, the performance of a data processing algorithm for determining the condition of the vehicle.

IPC Classes  ?

  • G08G 1/00 - Traffic control systems for road vehicles
  • G01S 13/931 - Radar or analogous systems, specially adapted for specific applications for anti-collision purposes of land vehicles

18.

INFORMATION PROCESSING SYSTEM, PROGRAM, AND INFORMATION PROCESSING METHOD

      
Application Number JP2024025605
Publication Number 2025/047159
Status In Force
Filing Date 2024-07-17
Publication Date 2025-03-06
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Nakagawa, Satoshi
  • Kuniyoshi, Yasuo

Abstract

[Problem] To provide an information processing system and the like capable of facilitating the enhancement of accuracy in the estimation result of the QOL of a user. [Solution] One aspect of the present invention provides an information processing system comprising a processor, wherein the processor: in a first acquisition step, acquires correlation information having a correlation with the quality of life (QOL) of a user, the correlation information including two or more types of information that can be acquired in association with an operation at the time of utterance of the user; and, in a first output step, outputs a score indicating the QOL of the user on the basis of the acquired correlation information.

IPC Classes  ?

  • G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
  • G10L 15/10 - Speech classification or search using distance or distortion measures between unknown speech and reference templates
  • G10L 15/22 - Procedures used during a speech recognition process, e.g. man-machine dialog
  • G10L 25/66 - Speech or voice analysis techniques not restricted to a single one of groups specially adapted for particular use for comparison or discrimination for extracting parameters related to health condition
  • G16H 20/70 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training

19.

ENGINEERED PROTEIN

      
Application Number JP2024030010
Publication Number 2025/047611
Status In Force
Filing Date 2024-08-23
Publication Date 2025-03-06
Owner
  • CURREIO, INC. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (Japan)
  • JICHI MEDICAL UNIVERSITY (Japan)
  • NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (Japan)
Inventor
  • Nureki Osamu
  • Nakagawa Ryoya
  • Omura Satoshi
  • Kise Yoshiaki
  • Hoshino Atsushi
  • Hino Tomohiro
  • Matoba Satoaki
  • Ohmori Tsukasa
  • Saika Hiroaki
  • Toki Seiichi
  • Ishibashi Kazuhiro

Abstract

The present invention provides an engineered protein that can be utilized as a genome engineering tool. The protein comprises the amino acid sequence represented by SEQ ID NO: 1 in which amino acid at position 188 is substituted with histidine, the amino acid sequence further including one selected from: substitution of amino acid at position 2 with tyrosine; substitution of amino acid at position 70 with tyrosine; substitution of amino acid at position 80 with arginine; substitution of amino acid at position 105 with threonine; substitution of amino acid at position 123 with histidine; substitution of amino acid at position 195 with lysine; substitution of amino acid at position 208 with arginine; substitution of amino acid at position 232 with alanine; substitution of amino acid at position 246 with methionine; substitution of amino acid at position 316 with methionine; and substitution of amino acid at position 337 with isoleucine.

IPC Classes  ?

20.

THERMOELECTRIC CONVERSION ELEMENT, THERMOELECTRIC CONVERSION MODULE, AND THERMOELECTRIC CONVERSION METHOD

      
Application Number JP2024031247
Publication Number 2025/047942
Status In Force
Filing Date 2024-08-30
Publication Date 2025-03-06
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • SUMITOMO CHEMICAL COMPANY, LIMITED (Japan)
Inventor
  • Okamoto Satoshi
  • Saitoh Eiji
  • Kikkawa Takashi
  • Hirata Yuya

Abstract

NN generated in the thermoelectric conversion section 202 due to the heat flow H input to the thermoelectric conversion section 202 from the outside along the first direction.

IPC Classes  ?

  • H10N 15/00 - Thermoelectric devices without a junction of dissimilar materialsThermomagnetic devices, e.g. using the Nernst-Ettingshausen effect
  • H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
  • H10D 48/40 - Devices controlled by magnetic fields
  • H10N 50/80 - Constructional details

21.

MEASUREMENT SYSTEM, MEASUREMENT METHOD, AND ANALYSIS DEVICE

      
Application Number JP2024022972
Publication Number 2025/047077
Status In Force
Filing Date 2024-06-25
Publication Date 2025-03-06
Owner
  • NIPPON TELEGRAPH AND TELEPHONE CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Wada Masaki
  • Matsui Takashi
  • Iida Hiroyuki
  • Nakajima Kazuhide
  • Murayama Hideaki
  • Wada Ryota

Abstract

Provided are a measurement system, a measurement method, and an analysis device that are capable of easily improving accuracy in measuring the shape of a linear structure. This measurement system for measuring the shape of a linear structure comprises a strain distribution measurement device 4 that, using a multicore optical fiber fixed along the extension direction of the linear structure, measures strain distributions that follow in the extension direction of the multicore optical fiber at two different timings or measures the difference between the strain distributions; and an analysis device 5 for calculating the shape of the multicore optical fiber using the difference between the strain distributions measured at two different timings and calculating the shape of the linear structure on the basis of the shape of the multicore optical fiber.

IPC Classes  ?

  • G01B 11/16 - Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge

22.

METHOD AND DEVICE FOR MEASURING BIOMOLECULE

      
Application Number JP2024030105
Publication Number 2025/047629
Status In Force
Filing Date 2024-08-23
Publication Date 2025-03-06
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • PROVIGATE INC. (Japan)
Inventor
  • Sakata Toshiya
  • Tseng Alex Chi-Wei
  • Ito Narushi

Abstract

One embodiment of the present disclosure provides a method for measuring a biomolecule. This method comprises: providing a recognition unit that includes a conductive polymer and a molecular recognition pH indicator acting as a dopant for the conductive polymer and recognizing a target biomolecule; introducing a sample containing the target biomolecule into the recognition unit; measuring the electrical characteristics of the conductive polymer, on the basis of a reaction between the target biomolecule and the molecular recognition pH indicator which occurs when the target biomolecule is introduced; and determining the amount of the target biomolecule in the sample, on the basis of the measured electrical characteristics.

IPC Classes  ?

  • G01N 27/416 - Systems
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

23.

TOUGHENING OF SILICONE-BASED POLYMER MATERIAL WITH ADDITION OF POLYROTAXANE

      
Application Number JP2024031092
Publication Number 2025/047916
Status In Force
Filing Date 2024-08-29
Publication Date 2025-03-06
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Ito, Kohzo
  • Ando, Shota
  • Fulati, Ailifeire

Abstract

Provided is a composition which contains a silicone-based polymer material and a plurality of polyrotaxanes, wherein: each polyrotaxane has a plurality of cyclic molecules and a chain polymer that penetrates through openings of the plurality of cyclic molecules; and a polysiloxane chain is bonded to at least some of the plurality of cyclic molecules.

IPC Classes  ?

24.

NOVEL PRODRUG-TYPE ANTICANCER AGENT TARGETING CANCER-SPECIFIC ENZYME ACTIVITY

      
Application Number JP2024031416
Publication Number 2025/047983
Status In Force
Filing Date 2024-08-30
Publication Date 2025-03-06
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Urano Yasuteru
  • Fujita Kyohhei
  • Utsumi Takenori

Abstract

1nn

IPC Classes  ?

  • C07H 17/00 - Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
  • A61K 31/365 - Lactones
  • A61K 31/513 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
  • A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
  • A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
  • A61K 31/4745 - QuinolinesIsoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
  • A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
  • A61K 49/00 - Preparations for testing in vivo
  • A61P 35/00 - Antineoplastic agents
  • C07H 17/08 - Hetero rings containing eight or more ring members, e.g. erythromycins
  • C07K 5/068 - Dipeptides the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg

25.

METHOD FOR PRODUCING FIBER-REINFORCED COMPOSITE MATERIAL

      
Application Number JP2024017572
Publication Number 2025/047000
Status In Force
Filing Date 2024-05-13
Publication Date 2025-03-06
Owner
  • IHI CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Fukushima Yasuyuki
  • Shimogaki Yukihiro
  • Momose Takeshi
  • Sato Noboru
  • Otaka Yuhei
  • Kimura Shunsuke

Abstract

This method for producing a fiber-reinforced composite material involves: introducing, into an atmosphere-controllable reaction furnace, reinforcing fiber fabric including reinforcing fibers interwoven with each other and including voids having an aspect ratio of 35 or more between the reinforcing fibers; flowing a raw material gas including hydrogen and methyltrichlorosilane into the reaction furnace; and heating the reaction furnace so as to keep at least the reinforcing fiber fabric at a temperature exceeding 1000°C but not exceeding 1100°C while maintaining the reaction furnace at a pressure lower than atmospheric pressure to cause a reaction to form a coating film including silicon carbide in the voids, thereby bonding the reinforcing fibers to each other with the coating film.

IPC Classes  ?

26.

POSITIONING SYSTEM USING MUONS

      
Application Number JP2024029015
Publication Number 2025/041694
Status In Force
Filing Date 2024-08-14
Publication Date 2025-02-27
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • HUN-REN WIGNER RESEARCH CENTRE FOR PHYSICS (Hungary)
Inventor
  • Tanaka,hiroyuki
  • Varga,dezso

Abstract

Provided is a positioning system capable of performing positioning stably with high accuracy by using lightweight equipment. This positioning system includes a reference detector, a reception detector, a communication means for performing communication between the reference detector and the reception detector, and a calculation unit. The reference detector and the reception detector are each configured to detect a zenith angle and an azimuth angle of incident muons. The calculation unit is configured to calculate a relative position of the reception detector relative to the reference detector on the basis of at least the zenith angle and the azimuth angle. The reference detector and the reception detector each include an internal clock in which time points at which the muons are incident are continuously recorded. The calculation unit is further configured to synchronize the internal clocks of the reference detector and the reception detector on the basis of the continuously recorded time information.

IPC Classes  ?

  • G01T 5/02 - Processing of tracksAnalysis of tracks
  • G01T 1/17 - Circuit arrangements not adapted to a particular type of detector
  • G01T 1/18 - Measuring radiation intensity with counting-tube arrangements, e.g. with Geiger counters

27.

COMPOUND SEMICONDUCTOR CHIP

      
Application Number JP2024029452
Publication Number 2025/041759
Status In Force
Filing Date 2024-08-20
Publication Date 2025-02-27
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takahashi Satoru
  • Kadoya Shotaro
  • Michihata Masaki

Abstract

Provided is a compound semiconductor chip that makes it possible to eliminate or reduce generation of BPD in an edge termination region of the compound semiconductor chip, and improve long-term reliability of a power device. A porous layer 13 is formed in the edge termination region 12 of a SiC chip 10, and thus generation of BPD in the edge termination region 12 can be eliminated or reduced. Particularly, in the power device, it is possible to eliminate or suppress a phenomenon in which, when a large current is made to flow in the thickness direction, the BPD of the region 12 is expanded and a stacking fault is generated by a thermal stress when the device is heated to a high temperature due to resistance heat generation by energization and then returns to a normal temperature. Further, by removing the porous layer 13, which is fragile and easy to process as compared with a bulk, it is possible to realize a smooth chip having no defects in a peripheral side portion thereof.

IPC Classes  ?

  • H01L 21/301 - Treatment of semiconductor bodies using processes or apparatus not provided for in groups to subdivide a semiconductor body into separate parts, e.g. making partitions

28.

PRESSURE SENSOR

      
Application Number JP2024029889
Publication Number 2025/041842
Status In Force
Filing Date 2024-08-22
Publication Date 2025-02-27
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Someya Takao
  • Yokota Tomoyuki
  • Lee Sunghoon
  • Wang Haoyang

Abstract

[Problem] To provide a pressure sensor having a thin film form and flexibility, in particular, to provide a multi-point three-axis pressure sensor capable of detecting a pressure distribution in three axial directions. [Solution] The present invention comprises: a porous rubber layer 100 having a first main surface 101 and a second main surface 102; a light irradiation layer provided on the first main surface; and a light detection layer provided on the second main surface. The porous rubber layer is irradiated with a spot-like light along a direction from the first main surface toward the second main surface. A pressure applied to the porous rubber layer is measured on the basis of an intensity distribution, on the second main surface, of the spot-like light irradiated on the first main surface which changes according to the pressure applied to the porous rubber layer.

IPC Classes  ?

  • G01L 1/24 - Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis
  • G01L 1/00 - Measuring force or stress, in general
  • G01L 5/00 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes
  • G01L 5/166 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes for measuring several components of force using photoelectric means

29.

METAL COMPLEX

      
Application Number JP2024030046
Publication Number 2025/041856
Status In Force
Filing Date 2024-08-23
Publication Date 2025-02-27
Owner
  • DAIKIN INDUSTRIES, LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Yamauchi, Akiyoshi
  • Kishikawa, Yosuke
  • Sagisaka, Shigehito
  • Hayashi, Hisataka
  • Nakamura, Shingo
  • Horiguchi, Kazunori
  • Hoshiya, Naoyuki
  • Shimogaki, Yukihiro
  • Yamaguchi, Jun
  • Momose, Takeshi
  • Sato, Noboru

Abstract

The present invention provides a starting material complex for forming a metal thin film, the starting material complex having a central metal and a ligand that is coordinated to the central metal, wherein (i) the central metal has an atomic polarizability of 45 to 51, and satisfies the following conditions: polarization volume ≤ 200 and relative dielectric constant ≤ 2.20, or (ii) the central metal has an atomic polarizability of 52 to 90, and satisfies the following conditions: polarization volume ≤ 240 and relative dielectric constant ≤ 2.50.

IPC Classes  ?

  • C23C 16/18 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of metallic material from metallo-organic compounds
  • C07F 15/06 - Cobalt compounds
  • C23C 16/16 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of metallic material from metal carbonyl compounds
  • H10D 64/60 - Electrodes characterised by their materials

30.

CELL-ADHESIVE COMPOSITION AND POLYMER-COATED MICROPARTICLES

      
Application Number 18862002
Status Pending
Filing Date 2023-05-19
First Publication Date 2025-02-27
Owner
  • MARUZEN PETROCHEMICAL CO., LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Nishiura, Takao
  • Miyata, Kanjiro
  • Fujiura, Kento

Abstract

[Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity. [Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity. [Solution]A cell-adhesive composition according to the present invention includes an oxyethylene chain-containing polymer represented by the following general formula (1): [Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity. [Solution]A cell-adhesive composition according to the present invention includes an oxyethylene chain-containing polymer represented by the following general formula (1): [Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity. [Solution]A cell-adhesive composition according to the present invention includes an oxyethylene chain-containing polymer represented by the following general formula (1): (wherein, in the general formula (1), R1 is —(CH2)p—SH, —(CH2)p—N3, —(CH2)p—NH2, or —(CH2)p—COOH, and p is an integer of 1 to 5; R2 to R4 are each independently hydrogen or a C1-10 alkyl group; R5 is a C1-10 alkyl group; R6 is hydrogen or a C1-5 alkyl group; R7 is a C1-10 alkyl group; n is an integer of 5 to 1000; m is an integer of 1 to 10; and q is an integer of 0 to 5).

IPC Classes  ?

  • A61K 9/50 - Microcapsules
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 33/242 - GoldCompounds thereof
  • A61K 33/243 - PlatinumCompounds thereof
  • A61K 33/38 - SilverCompounds thereof
  • A61K 47/60 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol

31.

POWER SUPPLY APPARATUS AND POWER SUPPLY SYSTEM

      
Application Number 18947183
Status Pending
Filing Date 2024-11-14
First Publication Date 2025-02-27
Owner
  • DENSO CORPORATION (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Sumiya, Hayato
  • Takahashi, Eisuke
  • Yamaguchi, Nobuhisa
  • Fujimoto, Hiroshi
  • Shimizu, Osamu

Abstract

A power supply apparatus includes a power reception coil mounted to a moving object, a plurality of relay coils, and a power reception circuit connected with the power reception coil. The relay coils are configured to successively relay supply of electric power from a power transmission coil, which is arranged along a surface on which the moving object moves, to the power reception coil during movement of the moving object. Each of the relay coils includes a first coil and a second coil, which are configured to be magnetic-field-coupled respectively to the power transmission coil and the power reception coil, and a connection circuit that connects the first and second coils. The connection circuit includes at least one resonance capacitor involved in setting of a resonance frequency of at least one of the first and second coils. The at least one resonance capacitor has a parallel characteristic.

IPC Classes  ?

  • B60L 53/62 - Monitoring or controlling charging stations in response to charging parameters, e.g. current, voltage or electrical charge
  • B60L 53/12 - Inductive energy transfer
  • B60L 53/30 - Constructional details of charging stations
  • H02J 50/00 - Circuit arrangements or systems for wireless supply or distribution of electric power
  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
  • H02J 50/50 - Circuit arrangements or systems for wireless supply or distribution of electric power using additional energy repeaters between transmitting devices and receiving devices

32.

ROBOT ARM

      
Application Number JP2024028022
Publication Number 2025/041593
Status In Force
Filing Date 2024-08-06
Publication Date 2025-02-27
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Yokomura, Ryota
  • Fukui, Rui

Abstract

Provided is a robot arm capable of constructing a platform for work. This robot arm comprises a base 1, a first arm 2 that is rotatably connected to the base 1 at a first joint part, and a second arm 3 that is rotatably connected to the first arm 2 at a second joint part, wherein: the first arm 2 is capable of moving in a length direction of the first arm 2 with respect to the first joint part; the second arm 3 is capable of moving in a length direction of the second arm 3 with respect to the second joint part; and the robot arm can transform between a first orientation, in which the base 1, the first arm 2, and the second arm 3 are superimposed, and a second orientation, in which the first arm 2 extends in a vertical direction with respect to the base 1 and the second arm 3 is positioned at a lower end of the first arm 2 and extends in a horizontal or inclined manner.

IPC Classes  ?

  • B25J 9/06 - Programme-controlled manipulators characterised by multi-articulated arms
  • B25J 5/04 - Manipulators mounted on wheels or on carriages travelling along a guideway wherein the guideway is also moved, e.g. travelling crane bridge type
  • E01D 22/00 - Methods or apparatus for repairing or strengthening existing bridges

33.

COMPOUND HAVING ANTI-ENTAMOEBA HISTOLYTICA ACTIVITY

      
Application Number JP2024029163
Publication Number 2025/041718
Status In Force
Filing Date 2024-08-16
Publication Date 2025-02-27
Owner
  • NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION (Japan)
  • NAGOYA INSTITUTE OF TECHNOLOGY (Japan)
Inventor
  • Tsunematsu, Yuta
  • Nozaki, Tomoyoshi
  • Mori, Mihoko
  • Shizu, Ryota
  • Sumii, Yuji
  • Shibata, Norio
  • Nakano, Yumiko

Abstract

Provided is a compound having anti-Entamoeba histolytica activity. The present invention is a compound represented by general formula (1), a salt thereof, or a solvate thereof.

IPC Classes  ?

  • C07D 303/16 - Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
  • A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
  • A61K 31/4427 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61P 33/04 - Amoebicides
  • A61P 35/00 - Antineoplastic agents
  • C07D 303/14 - Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
  • C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
  • C12P 7/26 - Ketones

34.

ULTRASONIC PROBE

      
Application Number JP2024029724
Publication Number 2025/041810
Status In Force
Filing Date 2024-08-21
Publication Date 2025-02-27
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takamatsu Seiichi
  • Noda Takumi
  • Tomii Naoki
  • Sakuma Ichiro

Abstract

[Problem] To provide an ultrasonic probe with which monitoring can be performed continuously for a long period of time. [Solution] This ultrasonic probe is formed by comprising: a lower fabric on which an electrode and a wiring are printed; an upper fabric on which an electrode and a wiring are printed; and one or more ultrasonic elements that are provided between the lower fabric and the upper fabric and are electrically connected to the electrode printed on the lower fabric and the electrode printed on the upper fabric. The electrode and the wiring printed on the lower fabric are provided so as to fill gaps between fibers of the lower fabric.

IPC Classes  ?

  • A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves

35.

METHOD FOR MANUFACTURING THIN FILM

      
Application Number JP2024030048
Publication Number 2025/041857
Status In Force
Filing Date 2024-08-23
Publication Date 2025-02-27
Owner
  • DAIKIN INDUSTRIES, LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Yamauchi, Akiyoshi
  • Kishikawa, Yosuke
  • Sagisaka, Shigehito
  • Hayashi, Hisataka
  • Nakamura, Shingo
  • Horiguchi, Kazunori
  • Shimogaki, Yukihiro
  • Yamaguchi, Jun
  • Momose, Takeshi
  • Sato, Noboru

Abstract

[Problem] To provide a method for manufacturing a thin film having further reduced resistivity. [Solution] A method for manufacturing a thin film, the method comprising: a deposition process for depositing a raw material compound on a substrate by an atomic layer deposition method using the raw material compound; and a film formation process for forming a thin film by reducing the raw material compound with a reducing gas at a pressure of at least 4.5 Torr after the deposition process.

IPC Classes  ?

  • C23C 16/455 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for introducing gases into the reaction chamber or for modifying gas flows in the reaction chamber
  • C23C 16/16 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of metallic material from metal carbonyl compounds
  • C23C 16/18 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of metallic material from metallo-organic compounds
  • C23C 16/448 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for generating reactive gas streams, e.g. by evaporation or sublimation of precursor materials
  • H01L 21/285 - Deposition of conductive or insulating materials for electrodes from a gas or vapour, e.g. condensation
  • H01L 21/3205 - Deposition of non-insulating-, e.g. conductive- or resistive-, layers, on insulating layersAfter-treatment of these layers
  • H01L 21/768 - Applying interconnections to be used for carrying current between separate components within a device
  • H01L 23/532 - Arrangements for conducting electric current within the device in operation from one component to another including external interconnections consisting of a multilayer structure of conductive and insulating layers inseparably formed on the semiconductor body characterised by the materials
  • H10D 64/60 - Electrodes characterised by their materials

36.

IL-23 SPECIFIC ANTIBODIES FOR THE TREATMENT OF SYSTEMIC SCLEROSIS

      
Document Number 03242957
Status Pending
Filing Date 2022-12-16
Open to Public Date 2025-02-26
Owner
  • JANSSEN BIOTECH, INC. (USA)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Fukasawa, Takemichi
  • Gao, Sheng
  • Kakui, Nobukazu
  • Kawashima, Naoko
  • Kimura, Takayuki
  • Morishima, Hitomi
  • Munoz, Ernesto
  • Rose, Shawn
  • Sakamoto, Takehiko
  • Sato, Shinichi
  • Toso, John
  • Ukyo, Yoshifumi
  • Yoshizaki, Ayumi
  • Zheng, Richuan

Abstract

A method of treating systemic sclerosis in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial dose and subsequent doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.

IPC Classes  ?

  • A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
  • C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons

37.

DETECTION DEVICE

      
Application Number 18940007
Status Pending
Filing Date 2024-11-07
First Publication Date 2025-02-20
Owner
  • Japan Display Inc. (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Nakamura, Takashi
  • Uchida, Makoto
  • Tada, Masahiro
  • Mochizuki, Marina
  • Kato, Hirofumi
  • Takimoto, Akio
  • Someya, Takao
  • Yokota, Tomoyuki

Abstract

A detection device includes a photodiode, and a thin-film transistor coupled to the photodiode. The thin-film transistor includes a semiconductor layer between a light-blocking layer and the photodiode, and an electrode layer between the semiconductor layer and the photodiode, and the electric layer includes a source electrode and a drain electrode of the thin-film transistor. The source electrode extends to a position facing the light-blocking layer with the semiconductor layer interposed therebetween.

IPC Classes  ?

38.

MANAGEMENT DEVICE, MANAGEMENT METHOD, AND MANAGEMENT PROGRAM

      
Application Number JP2024029008
Publication Number 2025/037632
Status In Force
Filing Date 2024-08-14
Publication Date 2025-02-20
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Kono, Tatsuoki
  • Kidohshi, Hideki
  • Kitayama, Atsushi
  • Kobayashi, Hikaru
  • Sugiyama, Masakazu

Abstract

This management device according to one embodiment comprises a green degree calculation unit. The green degree calculation unit calculates, as a green degree expressing the environmental contribution of hydrogen, the ratio of a renewable energy power amount to a power amount supplied only to a water electrolysis cell for generating hydrogen by water electrolysis using the supplied power. The green degree calculation unit outputs the green degree.

IPC Classes  ?

39.

ANTI-VSIG4 AND ANTI-SIGLEC-7 INHIBITORY ANTIBODY AGAINST INTERMOLECULAR INTERACTION BETWEEN VSIG4 AND SIGLEC -7

      
Application Number JP2024029185
Publication Number 2025/037646
Status In Force
Filing Date 2024-08-16
Publication Date 2025-02-20
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Ito, Takeshi
  • Murakami, Yoshinori

Abstract

The present invention addresses the problem of providing an anti-tumor immune response activator which inhibits an immune checkpoint function based on interaction between VSIG4 and Siglec-7, achieves an antibody having antitumor activity, and includes the antibody as an active ingredient. The present invention provides an anti-tumor immune response activator comprising an antibody that inhibits intermolecular interaction between VSIG4 and Siglec-7 or a functional fragment thereof.

IPC Classes  ?

  • C07K 16/42 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against immunoglobulins (anti-idiotypic antibodies)
  • A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
  • A61P 35/00 - Antineoplastic agents
  • A61P 37/04 - Immunostimulants
  • C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
  • C12N 15/13 - Immunoglobulins

40.

SHAPE MEASUREMENT SYSTEM AND SHAPE MEASUREMENT METHOD

      
Application Number 18706667
Status Pending
Filing Date 2022-11-29
First Publication Date 2025-02-20
Owner
  • NIPPON TELEGRAPH AND TELEPHONE CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Hanzawa, Nobutomo
  • Nakajima, Kazuhide
  • Matsui, Takashi
  • Murayama, Hideaki
  • Wada, Ryota
  • Kobayahsi, Makito

Abstract

The present disclosure is a shape measurement system including: a multi-core optical fiber in which four or more cores are disposed in a part other than the center of a cross section; a strain distribution measurement device configured to measure a strain distribution of each of the cores in a longitudinal direction of the multi-core optical fiber; and an analysis device configured to calculate a shape of the multi-core optical fiber by using the strain distribution of the multi-core optical fiber.

IPC Classes  ?

  • G01B 11/16 - Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge

41.

MEDICINE FOR STEATOHEPATITIS

      
Application Number 18714890
Status Pending
Filing Date 2022-12-05
First Publication Date 2025-02-13
Owner The University of Tokyo (Japan)
Inventor
  • Hayashi, Hisamitsu
  • Sabu, Yusuke
  • Tamura, Ryutaro

Abstract

It is an object of the present invention to provide a preventive agent, a therapeutic agent or a therapeutic composition for steatohepatitis developed by phospholipid deficiency or decreased phospholipid synthesis in the liver, and to provide a therapeutic method for the aforementioned disease. More specifically, the present invention relates to a therapeutic agent for steatohepatitis, comprising, as an active ingredient, choline or a choline metabolite, ethanolamine or an ethanolamine metabolite, a salt thereof, or a solvate thereof, wherein the therapeutic agent for steatohepatitis is characterized in that the steatohepatitis is developed by decreased phospholipid synthesis in the liver. Examples of the choline metabolite may include betaine, dimethylglycine, and phosphatidylcholine.

IPC Classes  ?

  • A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline
  • A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
  • A61K 31/205 - Amine addition salts of organic acidsInner quaternary ammonium salts, e.g. betaine, carnitine
  • A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
  • A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

42.

VEHICLE CONTROL DEVICE AND VEHICLE CONTROL METHOD

      
Application Number JP2024027746
Publication Number 2025/033352
Status In Force
Filing Date 2024-08-02
Publication Date 2025-02-13
Owner
  • MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHA (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takahashi, Ryota
  • Fujimoto, Hiroshi
  • Fuse, Hiroyuki
  • Takahashi, Naoki
  • Okamura, Yutaro
  • Ishihara, Yuji

Abstract

SDSHDHSLDLSDSDSDD) after the limitations, the sum model (M1), and the difference model (M2).

IPC Classes  ?

  • B60L 15/20 - Methods, circuits or devices for controlling the propulsion of electrically-propelled vehicles, e.g. their traction-motor speed, to achieve a desired performanceAdaptation of control equipment on electrically-propelled vehicles for remote actuation from a stationary place, from alternative parts of the vehicle or from alternative vehicles of the same vehicle train for control of the vehicle or its driving motor to achieve a desired performance, e.g. speed, torque, programmed variation of speed
  • B60W 30/00 - Purposes of road vehicle drive control systems not related to the control of a particular sub-unit, e.g. of systems using conjoint control of vehicle sub-units

43.

METHOD FOR ANALYZING STRUCTURAL VARIATION, PRIMER PAIR SET, AND METHOD FOR DESIGNING PRIMER PAIR SET

      
Application Number 18697422
Status Pending
Filing Date 2022-09-28
First Publication Date 2025-02-13
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor Yokoyama, Kazuaki

Abstract

An analysis method suitable for each SV is provided by utilizing a structural characteristic of the SV. The analysis method is a method for analyzing the presence/absence of a specific structural variation in a sample DNA including a genomic DNA, a free DNA, or a complementary DNA derived from a subject, and including a detection step of detecting the presence/absence of the specific structural variation by performing PCR using the sample DNA as a template, and using, as a primer, a primer pair set consisting of a first primer pair and a second primer pair.

IPC Classes  ?

  • C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
  • C12Q 1/6858 - Allele-specific amplification
  • C12Q 1/686 - Polymerase chain reaction [PCR]

44.

VEHICLE CONTROL DEVICE AND VEHICLE CONTROL METHOD

      
Application Number JP2024027744
Publication Number 2025/033350
Status In Force
Filing Date 2024-08-02
Publication Date 2025-02-13
Owner
  • MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHA (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takahashi, Ryota
  • Fujimoto, Hiroshi
  • Fuse, Hiroyuki
  • Takahashi, Naoki
  • Okamura, Yutaro
  • Ishihara, Yuji

Abstract

SDSDD) to the difference model (M2).

IPC Classes  ?

  • B60L 15/20 - Methods, circuits or devices for controlling the propulsion of electrically-propelled vehicles, e.g. their traction-motor speed, to achieve a desired performanceAdaptation of control equipment on electrically-propelled vehicles for remote actuation from a stationary place, from alternative parts of the vehicle or from alternative vehicles of the same vehicle train for control of the vehicle or its driving motor to achieve a desired performance, e.g. speed, torque, programmed variation of speed
  • B60W 30/00 - Purposes of road vehicle drive control systems not related to the control of a particular sub-unit, e.g. of systems using conjoint control of vehicle sub-units

45.

VEHICLE CONTROL DEVICE AND VEHICLE CONTROL METHOD

      
Application Number JP2024027745
Publication Number 2025/033351
Status In Force
Filing Date 2024-08-02
Publication Date 2025-02-13
Owner
  • MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHA (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takahashi, Ryota
  • Fujimoto, Hiroshi
  • Fuse, Hiroyuki
  • Takahashi, Naoki
  • Okamura, Yutaro
  • Ishihara, Yuji

Abstract

SDSDSDSS) are variably set.

IPC Classes  ?

  • B60L 15/20 - Methods, circuits or devices for controlling the propulsion of electrically-propelled vehicles, e.g. their traction-motor speed, to achieve a desired performanceAdaptation of control equipment on electrically-propelled vehicles for remote actuation from a stationary place, from alternative parts of the vehicle or from alternative vehicles of the same vehicle train for control of the vehicle or its driving motor to achieve a desired performance, e.g. speed, torque, programmed variation of speed
  • B60W 30/00 - Purposes of road vehicle drive control systems not related to the control of a particular sub-unit, e.g. of systems using conjoint control of vehicle sub-units

46.

METHOD AND DEVICE FOR DICING SIC WAFER

      
Application Number JP2024027912
Publication Number 2025/033382
Status In Force
Filing Date 2024-08-05
Publication Date 2025-02-13
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takahashi Satoru
  • Kadoya Shotaro
  • Michihata Masaki

Abstract

The present invention provides a method and a device for dicing an SiC wafer which: make it unnecessary to adjust the focal point of laser light; make it possible to perform dicing at the cut width as designed with the wafer cut surface vertical; prevent BPD expansion and/or cracks in a wafer cut section due to mechanical stress and/or thermal stress during dicing; prevent burning of the wafer cut surface; and make it possible to reduce residual debris on the wafer surface. Water guide laser processing is adopted in which, during dicing of an SiC wafer W, laser light R is allowed to pass through a high-pressure water beam 12, and the SiC wafer W is cut with the laser light R totally reflected by the inner wall of the water flow. Thus, it is unnecessary to adjust the focal point of the laser light R, it is possible to perform dicing at the cut width as designed with the wafer cut surface vertical, BPD expansion and/or cracks in a wafer cut section due to mechanical stress and/or thermal stress during dicing is/are prevented, burning of the wafer cut surface is prevented, and it is possible to reduce residual debris on the wafer surface.

IPC Classes  ?

  • H01L 21/301 - Treatment of semiconductor bodies using processes or apparatus not provided for in groups to subdivide a semiconductor body into separate parts, e.g. making partitions
  • B23K 26/38 - Removing material by boring or cutting
  • B23K 26/142 - Working by laser beam, e.g. welding, cutting or boring using a fluid stream, e.g. a jet of gas, in conjunction with the laser beamNozzles therefor for the removal of by-products
  • B23K 26/146 - Working by laser beam, e.g. welding, cutting or boring using a fluid stream, e.g. a jet of gas, in conjunction with the laser beamNozzles therefor the fluid stream containing a liquid

47.

NOVEL HVEM-BINDING PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

      
Application Number JP2024028824
Publication Number 2025/033553
Status In Force
Filing Date 2024-08-09
Publication Date 2025-02-13
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • RIKEN (Japan)
Inventor
  • Miyazono Kohei
  • Tanabe Ryo
  • Heldin Carl-Henrik
  • Westermark Bengt Anders
  • Matsumoto Takehisa
  • Shirouzu Mikako

Abstract

The purpose of the present invention is to provide a novel HVEM-binding protein. The present invention provides a human HVEM-binding protein comprising at least one immunoglobulin single variable region, wherein: the immunoglobulin single variable region includes complementarity determining regions 1-3 which have the amino acid sequence of SEQ ID NO: 1, the amino acid sequence of SEQ ID NO: 2, and the amino acid sequence of SEQ ID NO: 3, respectively; and the immunoglobulin single variable region is a humanized VHH. The protein according to the present invention may further comprise a human immunoglobulin Fc region or a human serum albumin-binding protein, and the immunoglobulin Fc region may be an Fc region of human IgG4.

IPC Classes  ?

  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
  • A61P 35/00 - Antineoplastic agents
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C07K 16/46 - Hybrid immunoglobulins
  • C12N 15/13 - Immunoglobulins
  • C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

48.

METHOD FOR MANUFACTURING BATTERY MATERIAL

      
Application Number 18784929
Status Pending
Filing Date 2024-07-26
First Publication Date 2025-02-06
Owner
  • Prime Planet Energy & Solutions, Inc. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Suzuki, Shinya
  • Ouchi, Takanari

Abstract

According to the present disclosure, a recovery efficiency of Li from a recovery object such as a used lithium ion secondary battery can be improved. The manufacture method disclosed herein includes a preparation step S11 of preparing a recovery object containing at least Li, and a chlorination heating step S12 of heating the recovery object together with a non-metal chlorine compound to produce LiCl. Since LiCl is soluble in water, Li can be easily recovered from the recovery object. That means, the technology disclosed herein makes it possible to separate Li from the recovery object immediately after the chlorination heating step S12, contributing to significant improvement of Li recovery efficiency.

IPC Classes  ?

  • C01D 15/08 - CarbonatesBicarbonates
  • C01D 15/02 - OxidesHydroxides
  • C01D 15/04 - Halides
  • C22B 1/08 - Chloridising roasting
  • C22B 3/00 - Extraction of metal compounds from ores or concentrates by wet processes
  • C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof
  • H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
  • H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
  • H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
  • H01M 10/54 - Reclaiming serviceable parts of waste accumulators

49.

PHOTOELECTRIC CONVERSION ELEMENT AND MANUFACTURING METHOD OF PHOTOELECTRIC CONVERSION ELEMENT

      
Application Number 18719749
Status Pending
Filing Date 2022-12-08
First Publication Date 2025-02-06
Owner
  • IDEMITSU KOSAN CO.,LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Nakamura, Motoshi
  • Takenaka, Issei
  • Segawa, Hiroshi
  • Tada, Keishi
  • Bessho, Takeru

Abstract

A photoelectric conversion element includes a light absorbing layer, a hole transport layer that transports holes generated by photoexcitation of the light absorbing layer, and a transparent conductive layer that is in contact with the hole transport layer and receives holes from the hole transport layer. The carrier density of the transparent conductive layer is more than 1×1016 cm−3 and 1×1020 cm−3 or less.

IPC Classes  ?

  • H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
  • H10K 30/57 - Photovoltaic [PV] devices comprising multiple junctions, e.g. tandem PV cells
  • H10K 30/86 - Layers having high hole mobility, e.g. hole-transporting layers or electron-blocking layers
  • H10K 71/10 - Deposition of organic active material
  • H10K 85/30 - Coordination compounds

50.

INFORMATION PROCESSING DEVICE, CONTROL DEVICE, AND RECORDING MEDIUM

      
Application Number JP2024027454
Publication Number 2025/028587
Status In Force
Filing Date 2024-07-31
Publication Date 2025-02-06
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Sugiyama, Hirokazu
  • Matsueda, Shungo
  • Hayashi, Yusuke

Abstract

An information processing device 1 obtains a range of values for a manipulated variable corresponding to a minimum constraint as a minimum solution set range, and sets a solution set range in which the range of solutions is limited inward of the minimum solution set range by a distance D determined by a ratio for the distance between an ideal value for the constraint and a value corresponding to the minimum constraint. The information processing device 1 then presents the solution set range, which is a restricted range of values for the manipulated variable.

IPC Classes  ?

  • G06Q 10/04 - Forecasting or optimisation specially adapted for administrative or management purposes, e.g. linear programming or "cutting stock problem"

51.

MANUFACTURING METHOD FOR BATTERY MATERIAL

      
Application Number 18784928
Status Pending
Filing Date 2024-07-26
First Publication Date 2025-02-06
Owner
  • Prime Planet Energy & Solutions, Inc. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Suzuki, Shinya
  • Ouchi, Takanari

Abstract

A manufacturing method disclosed herein includes a preparing step of preparing a collection target containing at least one of Ni and Co as a valuable metal, a heating step of heating the collection target at 500° C. or more so that at least a part of the valuable metal is reduced to a state of a metal simple substance, and an ammonia leaching step of immersing the collection target after the heating step in an ammonia aqueous solution in which ammonia, a pH buffer, and an oxidant are mixed, thereby obtaining a metal solution including the valuable metal.

IPC Classes  ?

  • H01M 4/04 - Processes of manufacture in general
  • H01M 4/02 - Electrodes composed of, or comprising, active material
  • H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
  • H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
  • H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

52.

METHOD FOR MANUFACTURING BATTERY MATERIAL

      
Application Number 18788130
Status Pending
Filing Date 2024-07-30
First Publication Date 2025-02-06
Owner
  • Prime Planet Energy & Solutions, Inc. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Suzuki, Shinya
  • Ouchi, Takanari

Abstract

A manufacture method disclosed herein includes: a preparation step S11 of preparing a recovery object; a measurement step S12 of measuring a quantity of oxygen element and a reducing component contained in the recovery object; a determination step S13 of determining whether or not a quantity ratio of the reducing component relative to oxygen element is higher than or equal to a threshold value based on a stoichiometric ratio of an oxide of the reducing component; a reducing component addition step S14 of adding the reducing component to the recovery object when a determined result value in the determination step is lower than the threshold value; and a heating step S15 of heating the recovery object under an inert atmosphere. This method makes it possible to reduce the valuable metal into an elemental metal, and therefore a valuable metal recovery efficiency can be improved.

IPC Classes  ?

  • H01M 10/54 - Reclaiming serviceable parts of waste accumulators
  • C22B 3/00 - Extraction of metal compounds from ores or concentrates by wet processes
  • C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof
  • C22B 15/00 - Obtaining copper
  • C22B 23/02 - Obtaining nickel or cobalt by dry processes

53.

METHOD FOR MANUFACTURING BATTERY MATERIAL

      
Application Number 18788131
Status Pending
Filing Date 2024-07-30
First Publication Date 2025-02-06
Owner
  • Prime Planet Energy & Solutions, Inc. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Suzuki, Shinya
  • Ouchi, Takanari

Abstract

The manufacture method disclosed herein includes: a preparation step of preparing a recovery object containing lithium and a first metal element; a chlorination heating step of heating the recovery object together with a metal chloride to produce LiCl; and a water dissolution step of immersing the recovery object after the chlorination heating step in water to dissolve LiCl in water to obtain a Li solution. In the manufacture method disclosed herein, a heating temperature in the chlorination heating step is 1000° C. or lower, and the metal chloride contains a second metal element that is more easily chlorinated than the first metal element in the recovered object and more hardly chlorinated than lithium in the chlorination heating step. Thereby, Li can be easily recovered from the recovery object at a low temperature of 1000° C. or lower.

IPC Classes  ?

  • H01M 10/54 - Reclaiming serviceable parts of waste accumulators
  • C22B 3/00 - Extraction of metal compounds from ores or concentrates by wet processes
  • C22B 3/30 - Oximes
  • C22B 3/32 - Carboxylic acids
  • C22B 3/38 - Treatment or purification of solutions, e.g. obtained by leaching by liquid-liquid extraction using organic compounds containing phosphorus
  • C22B 3/44 - Treatment or purification of solutions, e.g. obtained by leaching by chemical processes
  • C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof
  • C22B 23/02 - Obtaining nickel or cobalt by dry processes
  • C22B 26/12 - Obtaining lithium
  • C22B 47/00 - Obtaining manganese

54.

ANTIFERROMAGNETIC BODY MATERIAL, TWO-LAYER FILM OF MAGNETIC BODY AND INSULATOR, TUNNEL MAGNETORESISTIVE ELEMENT, AND MAGNETIC MEMORY

      
Application Number JP2024026734
Publication Number 2025/028421
Status In Force
Filing Date 2024-07-26
Publication Date 2025-02-06
Owner
  • JSR CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • TOHOKU UNIVERSITY (Japan)
Inventor
  • Toga,yuuta
  • Koretsune,takashi
  • Tanaka,katsuhiro
  • Nakatsuji,satoru

Abstract

31-xx1-pp3qr1-q-r1-q-r (0

IPC Classes  ?

  • H10N 50/10 - Magnetoresistive devices
  • H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
  • H10N 50/20 - Spin-polarised current-controlled devices
  • H10N 52/00 - Hall-effect devices

55.

INFORMATION PROCESSING SYSTEM, PROGRAM, AND INFORMATION PROCESSING METHOD

      
Application Number 18715271
Status Pending
Filing Date 2022-12-09
First Publication Date 2025-01-30
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Sakuma, Ichiro
  • Tomii, Naoki
  • Hori, Keisuke

Abstract

An information processing system is provided. This information processing system is equipped with an acquisition unit, a derivation unit, a detection unit and a generation unit. The acquisition unit acquires a first image sequence which expresses a change in membrane potential in biological tissue. The derivation unit derives a second image sequence which expresses a change in membrane potential by using a circulation variable on the basis of the first image sequence and a first derivation formula. The detection unit detects the position in the biological tissue at which the focal excitation wave is produced on the basis of the second image sequence and a first detection formula. The generation unit generates position information pertaining to the production position.

IPC Classes  ?

  • G06T 7/00 - Image analysis
  • G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS

56.

Gd-Co-BASED METALLIC POWDER, METHOD FOR PRODUCING SAME, ELECTROCONDUCTIVE MOLDED BODY, AND THERMOELECTRIC CONVERSION ELEMENT

      
Application Number JP2024024980
Publication Number 2025/023024
Status In Force
Filing Date 2024-07-10
Publication Date 2025-01-30
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • DOWA HOLDINGS CO., LTD. (Japan)
Inventor
  • Sakai Akito
  • Nakatsuji Satoru
  • Sato Kimitaka
  • Kumon Shoichi
  • Kato Shogo

Abstract

555 as a main component.

IPC Classes  ?

  • B22F 1/00 - Metallic powderTreatment of metallic powder, e.g. to facilitate working or to improve properties
  • B22F 1/05 - Metallic powder characterised by the size or surface area of the particles
  • B22F 9/04 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from solid material, e.g. by crushing, grinding or milling
  • C22C 1/00 - Making non-ferrous alloys
  • C22C 1/02 - Making non-ferrous alloys by melting
  • C22C 1/04 - Making non-ferrous alloys by powder metallurgy
  • C22C 1/047 - Making non-ferrous alloys by powder metallurgy comprising intermetallic compounds
  • C22C 19/07 - Alloys based on nickel or cobalt based on cobalt

57.

Cellulose Porous Particles, and Microcarrier for Culture Use which Comprises Same

      
Application Number 18717299
Status Pending
Filing Date 2022-12-08
First Publication Date 2025-01-30
Owner
  • The University of Tokyo (Japan)
  • ASAHI KASEI KABUSHIKI KAISHA (Japan)
Inventor
  • Hara, Yuichi
  • Harano, Kodai
  • Sano, Ayae
  • Ito, Taichi
  • Oki, Yuichiro
  • Inagaki, Natsuko

Abstract

Provided are: cellulose porous particles which have large surface areas on which cells can be attached, and on which cells can be adhered easily, and which rarely undergo the detachment of cells when the cells are cultured at a high density; and a microcarrier for culture use, which comprises the cellulose porous particles. The cellulose porous particles according to the present invention are composed of cellulose, in which the cellulose constituting the cellulose porous particles is modified by a cationic substituent and the cellulose constituting the celluose porous particles has a polypeptide bound thereto.

IPC Classes  ?

  • C08J 3/12 - Powdering or granulating
  • C07K 17/12 - Cellulose or derivatives thereof
  • C08K 5/17 - AminesQuaternary ammonium compounds
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

58.

ANTI-ADHESION COMPOSITION

      
Application Number 18903674
Status Pending
Filing Date 2024-10-01
First Publication Date 2025-01-30
Owner
  • Mochida Pharmaceutical Co., Ltd. (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Ito, Taichi
  • Ohta, Seiichi
  • Hasegawa, Kiyoshi
  • Isaji, Mitsuko
  • Shimizu, Satoshi
  • Tanaka, Daichi

Abstract

The purpose of this invention is to provide an anti-adhesion material having a high anti-adhesion effect, pertaining to an anti-adhesion material comprising a biocompatible sponge-like layered body having a sponge-like first layer and a sponge-like second layer both being at least partially crosslinked with a curing agent and comprising a low endotoxin monovalent metal salt of alginic acid. The monovalent metal salt of alginic acid in the first layer has a weight average molecular weight of 30000 to 300000. The monovalent metal salt of alginic acid in the second layer has a weight average molecular weight of 1000 to 200000. The weight average molecular weights are determined by GPC-MALS after a de-crosslinking treatment. The weight average molecular weight of the monovalent metal salt of alginic acid in the first layer is higher than the weight average molecular weight of the monovalent metal salt of alginic acid in the second layer.

IPC Classes  ?

  • A61L 31/14 - Materials characterised by their function or physical properties
  • A61L 31/04 - Macromolecular materials

59.

POLYMER GEL WITH HIGH STRENGTH AND HIGH VISCOSITY WITH IMIDAZOLIUM-BASED CATIONIC POLYMERIZATION INITIATOR

      
Application Number 18715618
Status Pending
Filing Date 2022-12-02
First Publication Date 2025-01-30
Owner
  • KIRIN HOLDINGS KABUSHIKI KAISHA (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takai, Madoka
  • Masuda, Tsukuru
  • Saegusa, Yui
  • Tsuji, Toshikazu

Abstract

A polymer gel includes a structure derived from a main monomer M1, a crosslinking agent monomer M2, and a radical polymerization initiator I as a constituent element. A monomer reactivity ratio r1 of the main monomer M1 and the monomer reactivity ratio r2 of the crosslinking agent monomer M2 satisfy a condition of r1>r2, a molar ratio of an addition amount of the crosslinking agent monomer M2 to an addition amount of the main monomer M1 is 12% or less, an addition molar ratio CM of the crosslinking agent monomer M2 to an addition amount of the main monomer M1, and an addition molar ratio IM of the initiator to an addition amount of the main monomer M1 satisfy a condition of IM≤0.66CM+0.0017, and the radical polymerization initiator I is a compound having a chemical structure of a general formula (I).

IPC Classes  ?

  • C08F 230/02 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
  • C08F 2/16 - Aqueous medium
  • C08F 222/38 - Amides

60.

EDIBLE MICROCARRIER, COMPOSITION, AND METHOD FOR PRODUCING SAME

      
Application Number JP2024026523
Publication Number 2025/023286
Status In Force
Filing Date 2024-07-24
Publication Date 2025-01-30
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takeuchi, Shoji
  • Morimoto, Yuya
  • Okada, Kensei
  • Nie, Minghao
  • Hasegawa, Asa

Abstract

The present invention provides an edible microcarrier comprising an edible gel and plasma.

IPC Classes  ?

  • A23L 13/00 - Meat productsMeat mealPreparation or treatment thereof
  • C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
  • C12N 5/078 - Cells from blood or from the immune system

61.

GUIDE RNA AND USE THEREOF

      
Application Number JP2024026682
Publication Number 2025/023307
Status In Force
Filing Date 2024-07-25
Publication Date 2025-01-30
Owner
  • C4U CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • RIKEN (Japan)
Inventor
  • Mashimo Tomoji
  • Yoshimi Kazuto
  • Takeshita Kohei
  • Kobori Shungo

Abstract

The present invention pertains to: a guide RNA having, on the 5' side of a spacer sequence, a repeat sequence that is cleaved through processing for forming a cascade complex, and not having a repeat sequence or having a sequence that is not cleaved through processing for forming a cascade complex, on the 3' side of the spacer sequence; and a type-I CRISPR-Cas system using the guide RNA.

IPC Classes  ?

  • C12N 15/09 - Recombinant DNA-technology
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

62.

THERMOELECTRIC CONVERSION ELEMENT AND THERMOELECTRIC CONVERSION DEVICE

      
Application Number JP2024024122
Publication Number 2025/022962
Status In Force
Filing Date 2024-07-03
Publication Date 2025-01-30
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • NITTO DENKO CORPORATION (Japan)
Inventor
  • Nakatsuji Satoru
  • Higo Tomoya
  • Mizuno Hayato
  • Nakanishi Yosuke
  • Yamagata Kazuto
  • Tanaka Hirokazu

Abstract

A thermoelectric conversion element 1a comprises a first sheet 10, a thermoelectric conversion part 30, and a second sheet 20. The first sheet 10, the thermoelectric conversion part 30, and the second sheet 20 are arranged in the order of the first sheet 10, the thermoelectric conversion part 30, and the second sheet 20 in the thickness direction of the first sheet 10. The thermoelectric conversion part 30 includes a magnetic body.

IPC Classes  ?

  • H10N 15/00 - Thermoelectric devices without a junction of dissimilar materialsThermomagnetic devices, e.g. using the Nernst-Ettingshausen effect
  • H02N 11/00 - Generators or motors not provided for elsewhereAlleged perpetua mobilia obtained by electric or magnetic means

63.

HEAT EXCHANGE PROMOTION MEMBER AND HEAT EXCHANGER

      
Application Number 18908257
Status Pending
Filing Date 2024-10-07
First Publication Date 2025-01-23
Owner
  • Atago Manufacturing Co., Ltd. (Japan)
  • The University of Tokyo (Japan)
  • DENSO CORPORATION (Japan)
Inventor
  • Otomo, Noboru
  • Yamamoto, Ken
  • Morimoto, Kenichi
  • Suzuki, Yuji

Abstract

Provided is a heat exchange promotion member and a heat exchanger that can improve heat transfer performance while holding down an increase in pressure drag of a fluid that exchanges heat with the heat exchange promotion member. A heat dissipation fin 14 of the present invention is a heat exchange promotion member that exchanges heat with a flowing fluid. The heat dissipation fin 14 includes a planar part 12 which is a surface substantially parallel to the fluid flowing direction and a raised part 13 that protrudes from the planar part 12 toward the fluid. The raised part 13 has a portion slanted relative to the direction in which the fluid flows, and there are a plurality of the raised parts 13 formed spaced apart from one another in the fluid flowing direction.

IPC Classes  ?

  • F28F 1/32 - Tubular elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with projections, with recesses the means being only outside the tubular element and extending transversely the means having portions engaging further tubular elements
  • F28F 1/34 - Tubular elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with projections, with recesses the means being only outside the tubular element and extending obliquely

64.

POLYMER GEL WITH HIGH STRENGTH AND HIGH VISCOSITY

      
Application Number 18715361
Status Pending
Filing Date 2022-12-02
First Publication Date 2025-01-23
Owner
  • KIRIN HOLDINGS KABUSHIKI KAISHA (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Takai, Madoka
  • Masuda, Tsukuru
  • Saegusa, Yui
  • Tsuji, Toshikazu

Abstract

There is disclosed a polymer gel including a structure derived from a main monomer M1, a crosslinking agent monomer M2, and a radical polymerization initiator I as a constituent element. In this polymer gel, a monomer reactivity ratio r1 of the main monomer M1 and a monomer reactivity ratio r2 of the crosslinking agent monomer M2 satisfy a condition of r1>r2, a molar ratio of an addition amount of the crosslinking agent monomer to an addition amount of the main monomer M1 is 1% or less, and a decomposition rate (10−7/s) of the radical polymerization initiator I at 25° C. is 25 or more. This polymer gel has properties of high strength and high viscosity.

IPC Classes  ?

  • C08J 3/075 - Macromolecular gels
  • C08F 220/18 - Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
  • C08F 220/36 - Esters containing nitrogen containing oxygen in addition to the carboxy oxygen
  • C08F 220/56 - AcrylamideMethacrylamide

65.

METHOD FOR MANUFACTURING MAGNETIC TUNNEL JUNCTION ELEMENT

      
Application Number JP2024025310
Publication Number 2025/018303
Status In Force
Filing Date 2024-07-12
Publication Date 2025-01-23
Owner
  • JSR CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Inukai Kouji
  • Toga Yuuta
  • Nakatsuji Satoru
  • Idzuchi Hiroshi

Abstract

Provided is a method for manufacturing a magnetic tunnel junction element provided with a magnetic tunnel junction layer and a metal layer in the stated order directly or indirectly on a substrate, the method comprising: a step for applying, to the metal layer, a resist composition containing a polymer that has a structural unit containing an aromatic ring; a step for exposing a resist film formed through the application step; a step for developing the exposed resist film; and a step for etching the magnetic tunnel junction layer and the metal layer using, as a mask, a resist pattern formed through the development step.

IPC Classes  ?

  • H10N 50/01 - Manufacture or treatment
  • G03F 7/004 - Photosensitive materials
  • G03F 7/039 - Macromolecular compounds which are photodegradable, e.g. positive electron resists
  • G03F 7/40 - Treatment after imagewise removal, e.g. baking
  • H05K 1/03 - Use of materials for the substrate
  • H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
  • H10N 50/20 - Spin-polarised current-controlled devices

66.

METHOD FOR MANUFACTURING MAGNETIC TUNNEL JUNCTION ELEMENT

      
Application Number JP2024025315
Publication Number 2025/018305
Status In Force
Filing Date 2024-07-12
Publication Date 2025-01-23
Owner
  • JSR CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Inukai Kouji
  • Toga Yuuta
  • Nakatsuji Satoru
  • Idzuchi Hiroshi

Abstract

A method for manufacturing a magnetic tunnel junction element comprising a magnetic tunnel junction layer and a metal layer directly or indirectly on a substrate in this order, the method comprising: a step for forming a resist underlayer film on the metal layer; a step for forming a silicon oxide film on the resist underlayer film; and a step for forming a resist film on the silicon oxide film, wherein the resist underlayer film is formed from a resist underlayer film-forming composition containing a compound having an aromatic ring and a solvent.

IPC Classes  ?

  • G03F 7/11 - Photosensitive materials characterised by structural details, e.g. supports, auxiliary layers having cover layers or intermediate layers, e.g. subbing layers
  • G03F 7/40 - Treatment after imagewise removal, e.g. baking
  • H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
  • H10N 50/01 - Manufacture or treatment
  • H10N 50/10 - Magnetoresistive devices
  • H10N 50/20 - Spin-polarised current-controlled devices

67.

NOVEL USE OF ONCOLYTIC GENE-MODIFIED MEASLES VIRUS

      
Document Number 03245759
Status Pending
Filing Date 2023-03-16
Open to Public Date 2025-01-23
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Moritoh, Kanako
  • Yoneda, Misako
  • Fujiyuki, Tomoko
  • Kai, Chieko

Abstract

The present invention addresses the problem of developing oncolytic gene-modified measles viruses that do not recognize SLAM (rMV-SLAMblind and rMV-V(-)-SLAMblind), as a tool for tumor therapy. The present invention provides: a pharmaceutical composition for inducing cellular immunity against tumor cells for treatment, said pharmaceutical composition containing an oncolytic gene-modified measles virus; and a method for inducing cellular immunity against residual tumor cells in vivo or metastatic or recurrent tumor cells that could not be eliminated by direct introduction of an oncolytic gene-modified measles virus, said method comprising directly introducing an oncolytic gene-modified measles virus into tumor cells to be treated and causing cell death.

IPC Classes  ?

  • A61K 35/768 - Oncolytic viruses not provided for in groups
  • A61P 35/04 - Antineoplastic agents specific for metastasis
  • C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
  • C12N 5/09 - Tumour cells
  • C12N 15/45 - Paramyxoviridae, e.g. measles virus, mumps virus, Newcastle disease virus, canine distemper virus, rinderpest virus, respiratory syncytial viruses

68.

Genus Hydrogenophilus Bacterium Transformant

      
Application Number 18904008
Status Pending
Filing Date 2024-10-01
First Publication Date 2025-01-23
Owner
  • Utilization of Carbon Dioxide Institute Co., Ltd. (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Yukawa, Hideaki
  • Ohtani, Naoto
  • Ishii, Masaharu

Abstract

The present disclosure provides a transformant obtained by introducing an aldehyde-alcohol dehydrogenase gene into a bacterium of the genus Hydrogenophilus.

IPC Classes  ?

  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
  • C12P 7/06 - Ethanol, i.e. non-beverage
  • C12P 7/16 - Butanols

69.

POLYMER COMPOUND

      
Application Number 18712061
Status Pending
Filing Date 2022-12-07
First Publication Date 2025-01-23
Owner
  • SHISEIDO COMPANY, LTD. (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Matsuo, Ayano
  • Gillet, Renaud
  • Sogabe, Atsushi
  • Honda, Satoshi
  • Oka, Minami

Abstract

A polymer compound in which coumarin or a derivative thereof is bonded to at least one terminal of a skeletal polymer. A flow property of the polymer compound is reversibly changeable from a first state to a second state by irradiation with light at a first wavelength and from the second state to the first state by irradiation with light at a second wavelength different from the first wavelength.

IPC Classes  ?

  • C08G 77/442 - Block- or graft-polymers containing polysiloxane sequences containing vinyl polymer sequences
  • C08G 77/52 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon in which at least two but not all the silicon atoms are connected by linkages other than oxygen atoms by carbon linkages containing aromatic rings

70.

METHOD AND KIT FOR EVALUATING ENZYME ACTIVITY

      
Application Number JP2024024651
Publication Number 2025/013837
Status In Force
Filing Date 2024-07-08
Publication Date 2025-01-16
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Komatsu Toru
  • Urano Yasuteru
  • Kagami Yu
  • Sakamoto Shingo

Abstract

Disclosed is a method for evaluating the oxidation activity of a dehydrogenase, the method comprising causing the dehydrogenase and DT-diaphorase to catalyze an oxidation-reduction reaction in an aqueous solution containing one molecule of the dehydrogenase, a substrate of the dehydrogenase, a nucleoside diphosphate derivative, the DT-diaphorase, and a fluorescent probe, and measuring the fluorescence after the reaction.

IPC Classes  ?

  • C12Q 1/32 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase involving dehydrogenase
  • G01N 33/533 - Production of labelled immunochemicals with fluorescent label

71.

NICOTIANA PLANT PRODUCTION METHOD AND TARGET PROTEIN MANUFACTURING METHOD

      
Application Number JP2024024682
Publication Number 2025/013843
Status In Force
Filing Date 2024-07-09
Publication Date 2025-01-16
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Matsuda, Ryo
  • Lee, Ji-Yoon
  • Yasumori, Naomi

Abstract

Provided is a nicotiana plant production method that requires less electricity and that improves production efficiency of a target protein. This nicotiana plant production method comprises: a step for cultivating a host nicotiana plant; a step for further cultivating the host nicotiana plant while irradiating the middle portion and the lower portion of the above-ground part of the host nicotiana plant with light (first irradiation step); a step for introducing the gene of a target protein into the host nicotiana plant (introduction step); and a step for further cultivating the nicotiana plant that has been introduced with the gene of the target protein while irradiating the middle portion and the lower portion of the above-ground part of the host nicotiana plant with light (second irradiation step).

IPC Classes  ?

  • A01H 6/82 - Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
  • A01G 22/45 - Tobacco
  • A01H 1/00 - Processes for modifying genotypes
  • A01H 5/00 - Angiosperms, i.e. flowering plants, characterised by their plant partsAngiosperms characterised otherwise than by their botanic taxonomy
  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12P 21/00 - Preparation of peptides or proteins
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • C12P 21/08 - Monoclonal antibodies

72.

HEPATOCYTES AND HEPATIC NON-PARENCHYMAL CELLS, AND METHODS FOR PREPARATION THEREOF

      
Application Number 18899155
Status Pending
Filing Date 2024-09-27
First Publication Date 2025-01-16
Owner The University of Tokyo (Japan)
Inventor
  • Miyajima, Atsushi
  • Kido, Taketomo
  • Koui, Yuta
  • Kobayashi, Ayaka

Abstract

The present invention pertains to hepatocytes, liver progenitor cells, cholangiocytes, liver sinusoidal endothelial progenitor cells, liver sinusoidal endothelial cells, hepatic stellate progenitor cells, hepatic stellate cells, and liver cellular tissue models, as well as to methods for preparing these cells. The present invention also pertains to a cell fraction comprising liver progenitor cells, liver sinusoidal endothelial progenitor cells, or hepatic stellate progenitor cells. The present invention also pertains to a pharmaceutical composition or kit comprising the above-mentioned cells, a liver cellular tissue model, or a cell fraction. The present invention also pertains to: a method for screening liver disease treatment agents; a method for evaluating the hepatotoxicity of drugs, hepatocytes for infectious disease models, and a method for preparing the same; infectious disease model tissues and a method for preparing the same; as well as a method for screening infectious liver disease treatment agents.

IPC Classes  ?

  • A61K 35/407 - LiverHepatocytes
  • C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

73.

FLAVORING COMPOSITION FOR ENHANCING SALTY TASTE, AND REDUCED-SODIUM SEASONING AND REDUCED-SODIUM FOOD OR DRINK PRODUCED BY USING FLAVORING COMPOSITION

      
Application Number JP2024024551
Publication Number 2025/013813
Status In Force
Filing Date 2024-07-08
Publication Date 2025-01-16
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • SALT SAVER CO. LTD. (Japan)
Inventor
  • Yamashita Haruyuki
  • Asakura Tomiko
  • Abe Keiko

Abstract

The present invention provides: a flavoring composition for reducing the sodium content in a food or drink without diminishing the salty taste; a reduced-sodium seasoning or a reduced-sodium food or drink produced by using the flavoring composition; and a method for producing said reduced-sodium seasoning or said reduced-sodium food or drink.

IPC Classes  ?

  • A23L 27/40 - Table saltsDietetic salt substitutes
  • A23B 7/10 - Preserving with acidsAcid fermentation
  • A23G 3/36 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by the composition
  • A23L 2/00 - Non-alcoholic beveragesDry compositions or concentrates thereforPreparation or treatment thereof
  • A23L 2/52 - Adding ingredients
  • A23L 7/13 - Snacks or the like obtained by oil frying of a formed cereal dough
  • A23L 7/161 - Puffed cereals, e.g. popcorn or puffed rice
  • A23L 13/00 - Meat productsMeat mealPreparation or treatment thereof
  • A23L 17/00 - Food-from-the-sea productsFish productsFish mealFish-egg substitutesPreparation or treatment thereof
  • A23L 23/00 - SoupsSauces Preparation or treatment thereof
  • A23L 27/00 - SpicesFlavouring agents or condimentsArtificial sweetening agentsTable saltsDietetic salt substitutesPreparation or treatment thereof
  • A23L 33/16 - Inorganic salts, minerals or trace elements

74.

AROMA CHEMICAL COMPOSITION AND MENSTRUAL CYCLE MARKER

      
Application Number JP2024024888
Publication Number 2025/013888
Status In Force
Filing Date 2024-07-10
Publication Date 2025-01-16
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Nuriya Shirasu Mika
  • Yamada Ohgi Nozomi
  • Touhara Kazushige

Abstract

The present invention addresses the problem of: providing an aroma chemical comprising a substance secreted characteristically in the ovulatory period, the aroma chemical, as a result of smelling the fragrance thereof, evoking a pleasant feeling, inducing a tranquil effect in men, and increasing allure in women; as well as providing substances (menstrual cycle markers) for specifying each period of the menstrual cycle, and a method for estimating menstrual cycles using said substances. Specifically, the present invention is an aroma chemical composition comprising one or more compounds selected from the group of compounds consisting of geranylacetone, 9-hexadecenoic acid, and tetradecanoic acid. The present invention also is a method for estimating the menstrual cycle of a subject, the method comprising the detection, in secreted substances from the axilla of the subject, of at least one compound selected from the group of compounds consisting of: octanal; 1-tetradecanol; 1,3-butanediol; 1-hexadecanol; hexanoic acid; dodecanal; propionic acid; 2,6,10,14-tetramethyl-pentadecane; heptadecane; 1-pentadecanol; (Z)-9-octadecenoic acid; 1-dodecanol, 1-octanol; hexahydro-2H-azepin-2-one; 1-tridecanol; tetradecane; octadecane; tetradecanoic acid; (E)-geranylacetone; (Z)-9-hexadecenoic acid; hydrogen sulfide; and 2-pyrrolidone.

IPC Classes  ?

  • C11B 9/00 - Essential oilsPerfumes
  • A61K 8/35 - Ketones, e.g. quinones, benzophenone
  • A61K 8/36 - Carboxylic acidsSalts or anhydrides thereof
  • A61Q 13/00 - Formulations or additives for perfume preparations
  • D06M 13/00 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials with non-macromolecular organic compoundsSuch treatment combined with mechanical treatment
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

75.

PHARMACEUTICAL, FOOD, AND COSMETIC COMPOSITIONS AND PRODUCTS

      
Application Number 18588968
Status Pending
Filing Date 2024-02-27
First Publication Date 2025-01-09
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • IDO MEDICAL CO., LTD. (Japan)
Inventor
  • Akiyama, Tetsu
  • Kamoshida, Yuki
  • Hayashi, Tomoatsu
  • Yamazumi, Yusuke
  • Oda, Takeaki
  • Shikanai, Mima
  • Kageyama, Yasunari
  • Kojima, Takuya

Abstract

A pharmaceutical composition comprising an effective amount of extracellular vesicles derived from a plant. A food composition comprising an effective amount of extracellular vesicles derived from a plant. A cosmetic composition comprising an effective amount of extracellular vesicles derived from a plant. For example, the plant is selected from the group consisting of coastal hog fennel, Madeira vine, lemongrass, green garlic, turmeric, crimson glory vine, and bitter melon.

IPC Classes  ?

  • A61K 36/23 - Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]

76.

Biomarker for Detecting Hepatocytes With Bile Ductular Proliferation

      
Application Number 18291509
Status Pending
Filing Date 2022-07-22
First Publication Date 2025-01-09
Owner
  • The University of Tokyo (Japan)
  • Kanagawa Prefectural Hospital Organization (Japan)
  • Tokyo Institute of Technology (Japan)
  • National University Corporation Kanazawa University (Japan)
Inventor
  • Seiki, Motoharu
  • Yamashita, Taro
  • Okada, Hikari
  • Kaneko, Shuichi
  • Koshikawa, Naohiko
  • Funahashi, Nobuaki

Abstract

The present invention provides a method of detecting a biomarker for detecting hepatocytes with bile ductular proliferation, the method including: detecting laminin γ2 single chain or a nucleic acid encoding the same as the biomarker in a specimen.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

77.

METHOD FOR MANUFACTURING MAGNETIC STORAGE ELEMENT

      
Application Number JP2024023703
Publication Number 2025/009492
Status In Force
Filing Date 2024-07-01
Publication Date 2025-01-09
Owner
  • JSR CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Inukai, Kouji
  • Toga, Yuuta
  • Ichinohe, Daigo
  • Shimizu, Makoto
  • Nakatsuji, Satoru
  • Idzuchi, Hiroshi

Abstract

The purpose of the present invention is to manufacture a fine-patterned magnetic storage element with high precision. A magnetic storage element (1) includes: a magnetic tunnel junction layer (30) having a structure in which an insulating layer (32) is sandwiched between two magnetic layers (31) and (33), and in which the resistance state changes in accordance with the magnetization direction of one of the magnetic layer (31) and the magnetic layer (33); and a metal layer (40) provided on the magnetic tunnel junction layer (30). A method for manufacturing the magnetic storage element (1) includes a step for forming a resist film (50) having an opening (50a) on a substrate (10) on which an electrode layer (20) is formed, a step for forming a magnetic tunnel junction layer (30) on the electrode layer (20) exposed in the opening (50a), a step for forming a metal layer (40) on the magnetic tunnel junction layer (30), and a step for removing the resist film (50).

IPC Classes  ?

  • H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
  • H01L 21/3205 - Deposition of non-insulating-, e.g. conductive- or resistive-, layers, on insulating layersAfter-treatment of these layers
  • H01L 21/768 - Applying interconnections to be used for carrying current between separate components within a device
  • H10N 50/10 - Magnetoresistive devices

78.

METHOD FOR PRODUCING DECELLULARIZED TISSUE OR ORGAN BY MEANS OF HYDROSTATIC PRESSURE

      
Application Number JP2024022991
Publication Number 2025/005081
Status In Force
Filing Date 2024-06-25
Publication Date 2025-01-02
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Sakai Furukawa, Katsuko
  • Ushida, Takashi
  • Wang, Dongzhe

Abstract

Disclosed is a method for producing a decellularized tissue or organ, the method comprising: a step for incorporating a DNA-degrading enzyme into an animal-derived tissue or organ; and a step for applying a hydrostatic pressure of 100-500 MPa in a medium that contains the DNA-degrading enzyme to the animal-derived tissue or organ into which the DNA-degrading enzyme has been incorporated.

IPC Classes  ?

  • A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
  • A61L 27/38 - Animal cells
  • A61L 27/60 - Materials for use in artificial skin

79.

PROTEIN SCINTILLATOR

      
Application Number JP2024023407
Publication Number 2025/005196
Status In Force
Filing Date 2024-06-27
Publication Date 2025-01-02
Owner
  • THE UNIVERSITY OF TOKYO (Japan)
  • OSAKA UNIVERSITY (Japan)
Inventor
  • Tanoi Keitaro
  • Chiba Takuma
  • Nagai Takeharu
  • Sugiura Kazunori

Abstract

The present invention addresses the problem of providing: a protein that acts as a scintillator; and a method for designing a protein that acts as a scintillator. According to the present invention, a use of a β-barrel-type fluorescent protein as a scintillator is provided, wherein the β-barrel-type fluorescent protein has a fluorescence peak at 500 nm or less. According to the present invention, a method for designing a protein that acts as a scintillator is also provided, the method comprising (A) a step for identifying a specific amino acid residue in an amino acid sequence for a β-barrel-type fluorescent protein being mutated and (B) a step for constructing, on the basis of the amino acid sequence for the protein being mutated, an amino acid sequence having a structure such that the amino acid residue identified in the step (A) is substituted by another specific amino acid residue.

IPC Classes  ?

  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C12M 1/00 - Apparatus for enzymology or microbiology
  • C12N 1/13 - Unicellular algaeCulture media therefor modified by introduction of foreign genetic material
  • C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
  • C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
  • C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 15/09 - Recombinant DNA-technology
  • C12N 15/12 - Genes encoding animal proteins
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

80.

GAS DETECTING SYSTEM AND GAS DETECTING METHOD

      
Application Number JP2024022875
Publication Number 2025/005053
Status In Force
Filing Date 2024-06-24
Publication Date 2025-01-02
Owner
  • DAIKIN INDUSTRIES, LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Aotani, Shun
  • Sagisaka, Shigehito
  • Zhao, Moju
  • Yukawa, Ryunosuke
  • Nagato, Keisuke
  • Nakao, Masayuki

Abstract

Provided is a technique capable of efficiently detecting chemical substances with reduced power consumption. This gas detecting system comprises: a ground-level moving body that can move along the ground; one or more flying bodies that are mounted on the ground-level moving body and that can float in the air; and a sensor that is provided on at least the one or more flying bodies to detect a chemical substance in a gas. The gas detecting system performs detection using the sensor in a first mode in which the one or more flying bodies are mounted on the ground-level moving body, and then transitions to a second mode in which the one or more flying bodies are allowed to float from the ground-level moving body, and performs detection using the sensor.

IPC Classes  ?

  • G01M 3/20 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
  • B64U 10/13 - Flying platforms
  • B64U 80/86 - Land vehicles
  • G01M 3/02 - Investigating fluid tightness of structures by using fluid or vacuum
  • G05D 1/43 - Control of position or course in two dimensions
  • G05D 1/46 - Control of position or course in three dimensions
  • G08B 21/12 - Alarms for ensuring the safety of persons responsive to undesired emission of substances, e.g. pollution alarms
  • B64U 101/35 - UAVs specially adapted for particular uses or applications for science, e.g. meteorology

81.

INFORMATION PROCESSING SYSTEM AND INFORMATION PROCESSING METHOD

      
Application Number 18273923
Status Pending
Filing Date 2022-01-21
First Publication Date 2024-12-26
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Irie, Hidetsugu
  • Sakai, Shuichi
  • Michigami, Kazuma
  • Tomida, Kazutaka

Abstract

An information processing system has a storage unit, a determination unit, and a control unit. The storage unit stores an approximation level related to a calculation. The approximation level can be changed during execution of the calculation. During the execution of the calculation, the determination unit determines whether to carry out a first process or a second process according to a probability determined on the basis of the approximation level stored in the storage unit. The second process is an approximation process of the first process. The control unit carries out control so as to carry out the process determined by the determination unit.

IPC Classes  ?

  • H04N 23/611 - Control of cameras or camera modules based on recognised objects where the recognised objects include parts of the human body
  • G06F 8/41 - Compilation

82.

MICRONEEDLE PATCH

      
Application Number 18692290
Status Pending
Filing Date 2022-06-30
First Publication Date 2024-12-26
Owner
  • LINTEC CORPORATION (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Koma, Yosuke
  • Kim, Beomjoon
  • Park, Jongho

Abstract

A microneedle structure of the present invention comprises: a liquid-impermeable base material that has a through-hole; a liquid-absorbable absorbent material that fills the through-hole; a needle-shaped portion that is provided on one surface side of the base material and has a flow channel formed therein; and a functional member that is provided on the other surface side of the base material. The needle-shaped portion and the absorbent material are connected to each other, and the absorbent material and the functional member are connected to each other.

IPC Classes  ?

  • A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value

83.

SYNTHESIS OF CEFAZOLIN UNDER SEQUENTIAL CONTINUOUS-FLOW CONDITIONS

      
Application Number JP2024022415
Publication Number 2024/262578
Status In Force
Filing Date 2024-06-20
Publication Date 2024-12-26
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Kobayashi, Shu
  • Ishitani, Haruro
  • Sugita, Shoichi

Abstract

The present disclosure relates to a sequential continuous-flow synthesis of cefazolin, which is a vital first-choice drug used for the prevention of primary infection in most surgeries, was investigated. Rapid flow and efficient mixing of substrates in suitable flow reactors enabled the target compound to be obtained in a short period without any intermediate isolation. A flexible system design that can be applied from a small-scale to medium-scale synthesis could be demonstrated, and optimal parameters were established to realize the synthesis. A 0.3 mol/h scale synthesis was achieved in 54% isolated yield with 13.75 g/h dL space-time-yield of cefazolin. The obtained material had an acceptable impurity profile and could be purified by simple acid-base extraction and precipitation.

IPC Classes  ?

  • C07D 501/36 - Methylene radicals, substituted by sulfur atoms

84.

MEASUREMENT METHOD USING SCANNING TRANSMISSION ELECTRON MICROSCOPE, SCANNING TRANSMISSION ELECTRON MICROSCOPE SYSTEM, AND PROGRAM

      
Application Number JP2024022523
Publication Number 2024/262601
Status In Force
Filing Date 2024-06-21
Publication Date 2024-12-26
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Seki Takehito
  • Shibata Naoya
  • Nogami Mitsuru
  • Ooe Kousuke
  • Ikuhara Yuichi

Abstract

A scanning transmission electron microscope system (100) comprises: an irradiation source (102) that generates an electron beam (EB); a lens (104) that converges the electron beam (EB) toward a sample (S); a detector (106) that detects the electron beam (EB) transmitted through the sample (S), and acquires a detection signal which is a four-dimensional data set represented by a two-dimensional scan position on the sample (S) and by two-dimensional coordinates on the detector surface; and a computer (108) that performs a Fourier transform on the detection signal acquired by the detector (106) with respect to the scan position, obtains Fourier transform data of a complex number represented by a two-dimensional spatial frequency and two-dimensional coordinates, calculates, for a specific spatial frequency, the thickness of the sample (S) and the inclination of the sample (S) with respect to a prescribed direction, from the amplitude of the Fourier transform data, and calculates the aberration of the lens (104) from the phase of the Fourier transform data.

IPC Classes  ?

  • H01J 37/28 - Electron or ion microscopesElectron- or ion-diffraction tubes with scanning beams
  • G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material

85.

CONGESTION DEGREE MEASUREMENT DEVICE, CONGESTION DEGREE MEASUREMENT SYSTEM, CONGESTION DEGREE MEASUREMENT METHOD, AND CONGESTION DEGREE MEASUREMENT PROGRAM

      
Application Number JP2023022621
Publication Number 2024/261821
Status In Force
Filing Date 2023-06-19
Publication Date 2024-12-26
Owner
  • MITSUBISHI ELECTRIC CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Shimizu Shogo
  • Hattori Ryoji
  • Kodaira Takayuki
  • Tanida Sakurako
  • Feliciani Claudio
  • Nishinari Katsuhiro

Abstract

A congestion degree measurement device (1) includes: a data reception unit (10) that receives wireless data based on wireless signals received by one or more wireless sensors (Sen#1 to Sen#I) at a location (9) set for receiving visitors (Gst#1 to Gst#Z); a visitor count calculation unit (20) that, on the basis of wireless data, or on the basis of permanently installed wireless terminal information acquired as information relating to the wireless data and to permanently installed wireless terminals (Dev#1 to Dev#X) for transmitting wireless signals, calculates a mobile wireless terminal count, which is the number of mobile wireless terminals (Mob#1 to Mob#Y) that are carried by the visitors (Gst#1 to Gst#Z) present at the location (9) and that transmit wireless signals, and calculates a visitor count, which is the number of visitors (Gst#1 to Gst#Z), from the mobile wireless terminal count; and a congestion degree calculation unit (30) that, on the basis of the visitor count, calculates a congestion degree indicating the degree of congestion by the visitors (Gst#1 to Gst#Z) at the location (9).

IPC Classes  ?

86.

SENSOR DEVICE

      
Application Number 18743228
Status Pending
Filing Date 2024-06-14
First Publication Date 2024-12-26
Owner
  • SUMITOMO HEAVY INDUSTRIES, LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Okazaki, Osamu
  • Usami, Yoshihisa
  • Takeya, Junichi
  • Yamashita, Yu

Abstract

A sensor device that detects information related to a load or a torque acting on a detection object includes a plurality of sensor members that are attached to the detection object and are connected in parallel, and an estimation unit that estimates the information related to the load or the torque acting on the detection object based on detected values of the plurality of sensor members.

IPC Classes  ?

  • G01L 3/14 - Rotary-transmission dynamometers wherein the torque-transmitting element is other than a torsionally-flexible shaft

87.

IMMUNOSTIMULATORY HERPES VIRUS

      
Application Number JP2024022411
Publication Number 2024/262576
Status In Force
Filing Date 2024-06-20
Publication Date 2024-12-26
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor Todo Tomoki

Abstract

Provided is an oncolytic herpes simplex virus having a gene encoding an immune checkpoint inhibitor. This herpes simplex virus preferably has the following features (a)-(c). (a) The ICP6 gene is deleted or inactivated, (b) the γ34.5 gene is deleted or inactivated, and (c) the α47 gene is deleted or inactivated. Since the expressed immune checkpoint inhibitor remains at the tumor locus and does not flow out into the blood, systemic side effects are not generated.

IPC Classes  ?

  • C12N 7/01 - Viruses, e.g. bacteriophages, modified by introduction of foreign genetic material
  • A61K 35/763 - Herpes virus
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
  • A61P 35/00 - Antineoplastic agents
  • A61P 37/04 - Immunostimulants
  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C12N 15/13 - Immunoglobulins

88.

MONOCLONAL ANTIBODY-CONTAINING COMPOSITION FOR SUPPRESSING CLOSTRIDIUM DIFFICILE BACTERIA

      
Application Number 18574919
Status Pending
Filing Date 2022-06-30
First Publication Date 2024-12-19
Owner The University of Tokyo (Japan)
Inventor
  • Shinkura, Reiko
  • Morita, Naoki
  • Tamano, Ryutaro

Abstract

The present invention relates to a composition comprising a monoclonal antibody binding to Clostridium difficile (C. difficile) for inhibiting a growth of Clostridium difficile (C. difficile), and a use thereof. In addition, the present invention discloses the composition for treating an inflammatory bowel disease, and a use thereof.

IPC Classes  ?

  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61P 31/04 - Antibacterial agents

89.

CONTROL SYSTEM AND CONTROL METHOD

      
Application Number 18706684
Status Pending
Filing Date 2022-11-29
First Publication Date 2024-12-19
Owner
  • NIPPON TELEGRAPH AND TELEPHONE CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Hanzawa, Nobutomo
  • Nakajima, Kazuhide
  • Matsui, Takashi
  • Murayama, Hideaki
  • Wada, Ryota

Abstract

The present disclosure is a control system configured to: collect a strain distribution of an underwater structure connected to an above-water structure; and control at least one of the underwater structure and the above-water structure in accordance with the strain distribution.

IPC Classes  ?

  • E21B 47/001 - Survey of boreholes or wells for underwater installations
  • G01M 5/00 - Investigating the elasticity of structures, e.g. deflection of bridges or aircraft wings

90.

ENZYME DETECTION METHOD AND ENZYME DETECTION KIT

      
Application Number JP2024021356
Publication Number 2024/257799
Status In Force
Filing Date 2024-06-12
Publication Date 2024-12-19
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Noji Hiroyuki
  • Ueno Hiroshi

Abstract

Provided are: an enzyme detection method by which enzymes for synthesizing ATP or ADP can be detected, highly sensitive detection at one molecular level can be performed for an enzyme not having a fluorescent substrate among the enzymes, and highly sensitive measurement of a disease biomarker or the like can be performed; and an enzyme detection kit used in the same. Provided are an enzyme detection method for detecting, from an enzyme sample, a target enzyme for synthesizing ADP or ATP, and an enzyme detection kit used in the same, the method comprising: a sample addition step for preparing a detection device including a microchamber array member in which a plurality of storage parts capable of being filled with a detection liquid are arranged, and filling the storage parts of the detection device with a detection liquid containing the enzyme sample and a hexokinase enzyme; and a detection step for detecting, from the detection liquid, a signal obtained by synthesizing ADP or ATP.

IPC Classes  ?

  • C12Q 1/48 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving transferase
  • C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
  • C12Q 1/50 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving transferase involving creatine phosphokinase

91.

COHERENT ISING MACHINE WITH OPTICAL ERROR CORRECTION FOR OPTIMIZATION SOLUTION GENERATOR SYSTEM AND METHOD

      
Application Number 18683096
Status Pending
Filing Date 2022-08-17
First Publication Date 2024-12-19
Owner
  • NTT RESEARCH, INC. (USA)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Reifenstein, Sam
  • Kako, Satoshi
  • Leleu, Timothee
  • Yamamoto, Yoshihisa

Abstract

A coherent Ising machine may comprise a pump pulse generator configured to generate optical signal pulses; an optical error correction circuit configured to generate optical error pulses; and a main ring cavity configured to store the optical signal pulses and the optical error pulses, wherein the optical error pulses cause the coherent Ising machine not to converge on a local minima of Ising solution and continue to explore nearby states.

IPC Classes  ?

  • G06N 3/067 - Physical realisation, i.e. hardware implementation of neural networks, neurons or parts of neurons using optical means
  • G06N 3/047 - Probabilistic or stochastic networks

92.

METHOD FOR DETECTING KIDNEY DYSFUNCTION DIAGNOSTIC MARKER, METHOD FOR DETERMINING RENAL PROGNOSIS, DETECTION KIT FOR KIDNEY DYSFUNCTION DIAGNOSTIC MARKER, AND KIDNEY DYSFUNCTION DIAGNOSTIC MARKER

      
Application Number 18703972
Status Pending
Filing Date 2022-10-26
First Publication Date 2024-12-19
Owner
  • The University of Tokyo (Japan)
  • Japanese Foundation for Cancer Research (Japan)
Inventor
  • Harita, Yutaka
  • Takizawa, Keiichi
  • Ueda, Koji

Abstract

A method for detecting a kidney dysfunction diagnostic marker, the method including measurement of an expression amount of MUC1 and/or MGAM in urinary extracellular vesicles derived from a subject.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

93.

METHOD FOR COVERING FIBER BODY

      
Application Number 18817465
Status Pending
Filing Date 2024-08-28
First Publication Date 2024-12-19
Owner
  • IHI CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Fukushima, Yasuyuki
  • Akikubo, Kazuma
  • Shimogaki, Yukihiro
  • Momose, Takeshi

Abstract

A method for covering a fiber body includes an impregnation condition determination process for, at a time of carrying out a chemical vapor infiltration to cover the fiber body with a ceramic, determining an infiltration temperature and an infiltration pressure that maximizes a film growth rate of the ceramic throughout the fiber body relative to the infiltration temperature; and an infiltration step for supplying a film gas including an ingredient of the ceramic to carry out the chemical vapor infiltration at the infiltration temperature and the infiltration pressure determined in the impregnation condition determination process.

IPC Classes  ?

94.

ANISOTROPIC CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING, METHODS AND USES THEREOF

      
Application Number IB2024055757
Publication Number 2024/256991
Status In Force
Filing Date 2024-06-12
Publication Date 2024-12-19
Owner
  • UNIVERSIDADE DE AVEIRO (Portugal)
  • UNIVERSITY OF TOKYO (Japan)
Inventor
  • Oliveira E Silva, Nuno João
  • Lourosa Sousa, Filipa
  • Lopes Costa, João Miguel
  • Augusto, Ana Margarida
  • Lunet Soeiro, Joana Filipa
  • M. Gaspar, Vítor
  • Mano, João
  • Ohkoshi, Shin-Ichi
  • Yoshikiyo, Marie
  • Namai, Asuka

Abstract

The present disclosure relates to anisotropic magnetic contrast agents containing iron oxide nanoparticles for low-field magnetic resonance scanners, to be applied in the production of morphology- free images, and/or recording/reading information in soft materials containing protons, using low-field magnetic resonance scanners.

IPC Classes  ?

  • A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
  • G01R 33/48 - NMR imaging systems

95.

METHOD FOR CONTROLLING PROTEIN FUNCTION

      
Application Number 18702120
Status Pending
Filing Date 2022-10-20
First Publication Date 2024-12-12
Owner The University of Tokyo (Japan)
Inventor
  • Sato, Moritoshi
  • Kawano, Fuun

Abstract

It is an object of the present invention to provide a method of reliably chemogenetically controlling the activity of a protein, and to provide a protein used in the present method. Specifically, the present invention relates to a plurality of protein fragments, which recover the activity of the protein when the plurality of protein fragments assemble, and in which each of the plurality of protein fragments is tagged with a degradation domain (DD) sequence. In addition, the present invention also relates to a method of regulating the activity of a protein in a cell, comprising: a step of introducing into a cell, a fusion of a DD sequence, and each fragment of a protein that has been split into fragments, such that the fragments recover the activity of the protein when they assemble; and a step of introducing a DD sequence-specific stabilizing factor into the cell.

IPC Classes  ?

  • C12N 15/90 - Stable introduction of foreign DNA into chromosome
  • C12N 9/22 - Ribonucleases
  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof

96.

TWO-LAYER FILM OF MAGNETIC BODY AND INSULATOR, TUNNEL MAGNETORESISTIVE ELEMENT, AND MAGNETIC MEMORY

      
Application Number JP2024020707
Publication Number 2024/253160
Status In Force
Filing Date 2024-06-06
Publication Date 2024-12-12
Owner
  • JSR CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
  • TOHOKU UNIVERSITY (Japan)
Inventor
  • Toga,yuuta
  • Inukai,kouji
  • Koretsune,takashi
  • Nomoto,takuya
  • Arita,ryotaro
  • Tanaka,katsuhiro
  • Minami,susumu
  • Nakatsuji,satoru

Abstract

A two-layer film of a magnetic body and an insulator according to the present invention comprises an antiferromagnetic layer that has a hexagonal crystal structure, with at least one surface thereof being the (10-10) plane of the antiferromagnetic body, and an insulator layer that is composed of two, three, or four kinds of atoms layered on the (10-10) plane. A two-layer film of a magnetic body and an insulator according to the present invention comprises an antiferromagnetic layer that has a hexagonal crystal structure, with at least one surface thereof being the (0001) plane of the antiferromagnetic body, and an insulator layer that is composed of two, three, or four kinds of atoms layered on the (0001) plane. A tunnel magnetoresistive element according to the present invention comprises a second antiferromagnetic film layer that is layered on the insulator of the two-layer film. A magnetic memory according to the present invention comprises a plurality of the tunnel magnetoresistive elements.

IPC Classes  ?

  • H10N 50/10 - Magnetoresistive devices
  • H01L 29/82 - Types of semiconductor device controllable by variation of the magnetic field applied to the device
  • H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices

97.

FIBER SHEET AND METHOD FOR PRODUCING SAME

      
Application Number JP2024019972
Publication Number 2024/253027
Status In Force
Filing Date 2024-05-31
Publication Date 2024-12-12
Owner
  • DKS CO. LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Saito Tsuguyuki
  • Fujisawa Shuji
  • Ishioka Shun
  • Zhang Haoguo
  • Goi Yosuke
  • Ito Yoshiki
  • Hashimoto Masayuki

Abstract

According to the present invention, the strength of a fiber sheet such as a paper is improved. A fiber sheet according to an embodiment contains cellulose fibers satisfying conditions (A) to (C), and the proportion of the cellulose fibers which satisfy (A) to (C) among all the cellulose fibers contained in the fiber sheet is 50 mass% or greater. (A) Anionic functional groups are comprised, with at least a portion of the same being salt-type. (B) The number average fiber width is 1 μm or greater. (C) When an aqueous suspension with a cellulose fiber concentration of 0.2 mass%, adjusted to 20°C, is filtered using a filter with 60 μm mesh openings, the content of the cellulose fibers in the filtrate is 0.06 mass% or less.

IPC Classes  ?

  • D21H 11/20 - Chemically or biochemically modified fibres
  • D21H 15/02 - Pulp or paper, comprising fibres or web-forming material characterised by features other than their chemical constitution characterised by configuration

98.

CARBON NANOTUBE MOLDED BODY, ELECTRODE FOR ELECTROCHEMICAL WATER SPLITTING AND METHOD FOR PRODUCING SAME, AND ELECTROCHEMICAL WATER SPLITTING DEVICE

      
Application Number JP2024017128
Publication Number 2024/252835
Status In Force
Filing Date 2024-05-08
Publication Date 2024-12-12
Owner
  • NIHON TRIM CO., LTD. (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Kabayama, Shigeru
  • Sakata, Ichiro
  • Fugetsu, Bunshi
  • Adavan Kiliyankil, Vipin

Abstract

Provided are: a carbon nanotube molded body containing carbon nanotubes, wherein the specific surface area of the carbon nanotube molded body is 700 m2/g or more, the pore distribution of the carbon nanotube molded body is 3-15 nm, the tensile strength of the carbon nanotube molded body is 45 MPa or more, and the Young's modulus of the carbon nanotube molded body is 1600 MPa or more; and a method for producing the carbon nanotube molded body. Also provided are: an electrode for electrochemical water splitting that contains the carbon nanotube molded body and platinum supported on the carbon nanotube molded body and a method for producing the same; and an electrochemical water splitting device provided with the electrode for electrochemical water splitting.

IPC Classes  ?

  • C01B 32/168 - After-treatment
  • C01B 3/02 - Production of hydrogen or of gaseous mixtures containing hydrogen

99.

INFORMATION PROCESSING DEVICE, PROGRAM, AND PATTERN CODE

      
Application Number 18681698
Status Pending
Filing Date 2022-07-28
First Publication Date 2024-12-05
Owner THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Miyashita, Leo
  • Tabata, Satoshi
  • Ishikawa, Masatoshi

Abstract

[Problem] To provide an information processing device, program, and pattern code that make it possible to quickly specify a position in a pattern. [Problem] To provide an information processing device, program, and pattern code that make it possible to quickly specify a position in a pattern. [Solution] In one embodiment of this invention, an information processing device is provided. The information processing device comprises a projection image generation unit, a decryption unit, and a phase specification unit. The projection image generation unit is configured so as to be capable of generating a projection image on the basis of predetermined pattern information and outputting the generated projection image to a projection device. The projection image comprises a clock pattern and a data pattern based on pattern information. The decryption unit is configured so as to be capable of decrypting the data pattern into values on the basis of a captured image obtained by imaging an object using an imaging device. The captured image is an image obtained by photographing the object when the projection image is being projected thereon by the projection device. The phase specification unit is configured so as to be capable of specifying the phases of each part of the object on the basis of the values and pattern information.

IPC Classes  ?

  • H04N 5/74 - Projection arrangements for image reproduction, e.g. using eidophor
  • G06T 5/80 - Geometric correction
  • G06T 11/60 - Editing figures and textCombining figures or text

100.

RECEPTION DEVICE, QUANTUM KEY DISTRIBUTION SYSTEM, AND METHOD FOR DETECTING QUANTUM SIGNAL

      
Application Number 18274029
Status Pending
Filing Date 2022-01-24
First Publication Date 2024-12-05
Owner
  • NEC Corporation (Japan)
  • National Institute of Information and Communications Technology (Japan)
  • NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japan)
  • The University of Tokyo (Japan)
Inventor
  • Yoshino, Ken-Ichiro
  • Fujiwara, Mikio
  • Tomita, Akihisa
  • Koashi, Masato
  • Takeoka, Masahiro

Abstract

An object is to prevent eavesdropping in quantum key distribution. A synchronization signal reception device receives a synchronization signal that is an optical signal for defining a timing at which a quantum signal is detected, and outputs a reference signal corresponding to the synchronization signal. A clock signal generation unit generates a clock signal in response to the reference signal. A photon detection device detects a photon of the quantum signal in response to the clock signal. A timing of the clock signal randomly changes within a predetermined range.

IPC Classes  ?

  • H04L 9/08 - Key distribution
  • H04B 10/70 - Photonic quantum communication
  • H04L 9/12 - Transmitting and receiving encryption devices synchronised or initially set up in a particular manner
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