An air conditioning system (1) includes a carbon dioxide separation device (20) configured to separate some or all of carbon dioxide from air that contains carbon dioxide, an electrolytic reduction device (30) configured to generate a hydrocarbon and oxygen using the separated carbon dioxide as a raw material, and an oxygen supply amount control device (40) configured to supply some or all of the oxygen generated by the electrolytic reduction device (30) to a space to be processed (10).
F24F 8/60 - Traitement, p. ex. purification, de l'air fourni aux locaux de résidence ou de travail des êtres humains autrement que par chauffage, refroidissement, humidification ou séchage en ajoutant de l'oxygène
C25B 15/02 - Commande ou régulation des opérations
C25B 15/08 - Alimentation ou vidange des réactifs ou des électrolytesRégénération des électrolytes
F24F 8/10 - Traitement, p. ex. purification, de l'air fourni aux locaux de résidence ou de travail des êtres humains autrement que par chauffage, refroidissement, humidification ou séchage par séparation, p. ex. par filtrage
2.
METHOD FOR DIAGNOSING COLORECTAL CANCER AND METHOD FOR EVALUATING EFFECT OF ADJUVANT CHEMOTHERAPHY APPLIED TO COLORECTAL CANCER PATIENT
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (Japon)
THE UNIVERSITY OF TOKYO (Japon)
JAPANESE FOUNDATION FOR CANCER RESEARCH (Japon)
NAGASAKI UNIVERSITY (Japon)
Inventeur(s)
Mimori, Koshi
Niida, Atsushi
Nagayama, Satoshi
Uno, Naoki
Abrégé
The present invention provides a method for detecting colorectal cancer in a subject, said method comprising a step for determining the methylation state of at least one of the FGD5 gene and the GPC6 gene in the subject.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
[Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity.
[Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity.
[Solution] An oxyethylene chain-containing polymer according to the present invention is represented by the following general formula (1):
[Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity.
[Solution] An oxyethylene chain-containing polymer according to the present invention is represented by the following general formula (1):
[Problem] Provided is an oxyethylene chain-containing polymer having excellent biocompatibility and still having excellent reactivity.
[Solution] An oxyethylene chain-containing polymer according to the present invention is represented by the following general formula (1):
(wherein, in the general formula (1), R1 is —(CH2)p—SH, —(CH2)p—N3, (CH2)p—NH2, or —(CH2)p—COOH, and p is an integer of 1 to 5; R2 to R4 are each independently hydrogen or a C1-10 alkyl group; R5 is a C1-10 alkyl group; R6 is hydrogen or a C1-5 alkyl group; R7 is a C1-10 alkyl group; n is an integer of 5 to 1000; m is an integer of 1 to 10; and q is an integer of 0 to 5).
The present invention addresses the problem of improving user-friendliness and efficiency in analyzing the extent of possibility that there is a mutation that affects the occurrence or progression of disease. A training unit of an information processing system including an analysis device for selecting cancer driver mutations of a test subject uses a plurality of training information sets to execute machine learning by using, as training information sets regarding a prescribed nucleic acid, information indicating known sequence mutations carrying adverse risks, and at least some clinically significant information regarding mutations from among a public database, a human gene polymorphism database, a database pertaining to drug-gene interactions and genome resources for new drug development, and a drug response database. When a prescribed sequence mutation is inputted, the training unit generates or updates an AI model for outputting a ranking of the degree of possibility that said sequence mutation is a target sequence mutation. A rescue filter unit reclassifies, to a higher rank, sequence mutations for which the degree of possibility output by the model is greater than or equal to a certain value. The abovementioned problem is solved through this configuration.
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (Israël)
THE UNIVERSITY OF TOKYO (Japon)
Inventeur(s)
Brik, Ashraf
Kamnesky, Guy
Suga, Hiroaki
Huang, Yichao
Rogers, Joseph
Abrégé
The present invention provides cyclic peptides, as well as methods of using the same, such as for ameliorating or treating a K63Ub-related disease in a subject in need thereof.
Provided are a catalyst and a method that enable the production of an olefin-based polymer, which has a polar group and is usable for various applications, at high catalytic activity. A metal complex shown in general formula (C1) (in the formula, M represents a palladium atom or a nickel atom, X represents a phosphorus atom (P), R5-R9 are as set forth in the claims, L represents an electron donating ligand, and q is 0, ½, 1, or 2) is used as a catalyst for polymerization of an olefin having a polar group.
C08F 4/80 - MétauxHydrures métalliquesComposés organiques de métalLeur utilisation comme précurseurs de catalyseurs choisis parmi les métaux non prévus dans le groupe choisis parmi les métaux du groupe du fer ou les métaux du groupe du platine
The present invention provides a humanized antibody or an antigen-binding fragment thereof that binds to a HEG1 protein, in which the antibody is capable of binding to a human HEG1 protein expressed in mesothelioma cells.
C07K 16/30 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
8.
CRYOGENIC HEAT SWITCH, METHOD FOR MANUFACTURING CRYOGENIC HEAT SWITCH, AND CONTINUOUS NUCLEAR ADIABATIC DEMAGNETIZATION REFRIGERATION UNIT
One aspect of the present invention provides a cryogenic heat switch. The cryogenic heat switch includes at least one switching portion, a first heat conducting portion, a second heat conducting portion, and a restricting portion. The at least one switching portion is configured to switch between a superconducting state and a normal conducting state upon application of a magnetic field equal to or greater than a critical magnetic field. The at least one switching portion in the normal conducting state has a higher thermal conductivity than the at least one switching unit in the superconducting state. The first heat conducting portion comprises a first base portion coupled to a first member and at least one first switching coupling portion. The at least one first switching coupling portion extends from the first base portion in a first direction and is coupled to a first end of the at least one switching portion. The at least one first switching coupling portion has a rigidity lower than that of the first base portion. The second heat conducting portion comprises a second base portion coupled to a second member and at least one second switching coupling portion. The at least one second switching coupling portion extends from the second base portion in a second direction and is coupled to a second end of the at least one switching portion. The at least one second switching coupling portion has a rigidity lower than that of the second base portion. The restricting portion is coupled to the first base portion and the second base portion without the at least one switching portion being interposed therebetween. The thermal conductivity of the restricting portion is lower than the thermal conductivity of the at least one switching portion in the superconducting state.
F25B 9/00 - Machines, installations ou systèmes à compression dans lesquels le fluide frigorigène est l'air ou un autre gaz à point d'ébullition peu élevé
H10N 60/30 - Dispositifs commutables entre les états supraconducteur et normal
9.
NUCLEIC ACID APTAMER AND BONE REGENERATION INDUCING MATERIAL CONTAINING SAID NUCLEIC ACID APTAMER
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES (Japon)
Inventeur(s)
Sakai Takamasa
Fujisawa Ayano
Tei Yuichi
Kamata Hiroyuki
Yamamoto Eiichi
Fukui Chie
Haishima Yuuji
Nomura Yusuke
Abrégé
[Problem] The problems addressed are to provide an NA-AP having excellent binding ability to BMP and to reduce the risk of ectopic ossification in bone regeneration treatment utilizing the same. [Solution] An NA-AP having specific binding ability to BMP and a bone regeneration inducing material of said NA-AP carried in a hydrogel were discovered.
C12N 15/115 - Aptamères, c.-à-d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
An object of the present invention is to provide a method capable of detecting activity of an enzyme that strictly recognizes a substrate, such as acetylcholinesterase (AChE). There is provided a method for detecting activity of an enzyme in a biological sample using a microdevice, the method including a step of bringing the biological sample into contact with a substrate analog or a natural substrate, and a compound represented by General Formula (I) below or a salt thereof, wherein the substrate analog or the natural substrate generates a compound A having a thiol group (R—SH), a selenol group (R—SeH), or a poly sulfur atom (R—(S)n-H) (R is a hydrogen atom or an alkyl group, and n is 1 to 5) by a reaction with the enzyme, and fluorescence is observed or measured, the fluorescence being emitted or enhanced from a fluorescent product generated by the reaction of the compound represented by General Formula (I) or the salt thereof with the thiol group, the selenol group, or the poly sulfur atom.
G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
C07F 7/08 - Composés comportant une ou plusieurs liaisons C—Si
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
C12Q 1/46 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une estérase une cholinestérase
11.
RAMAN SPECTROSCOPIC SIGNAL-ENHANCED NANOPARTICLES, RAMAN SPECTROSCOPIC SIGNAL-ENHANCED NANOPARTICLE DISPERSION, AND METHOD FOR PRODUCING RAMAN SPECTROSCOPIC SIGNAL-ENHANCED NANOPARTICLES
66]3-) and a hydrochloric acid solution of divalent copper ions (Cu2+ ions, copper (II) ions) is heated at 80°C for 24 hours to obtain a hydrochloric acid dispersion of the copper-substituted Prussian blue analog, and a step for drying the hydrochloric acid dispersion of the copper-substituted Prussian blue analog to obtain a powder of the copper-substituted Prussian blue analog, and have a particle size of 10-100 nm. In a state where a measurement target for Raman spectroscopy is adsorbed on the surface of the nanoparticles, Raman scattered light from the measurement target in light emitted from a light source is enhanced.
The present invention addresses the problem of providing a continuous long fiber that comprises an aliphatic copolymerized polyester, has excellent storage stability, and can solve a problem of unwinding defects, as well as a method for producing said continuous long fiber. This continuous long fiber comprises an aliphatic copolymerized polyester, wherein the aliphatic copolymerized polyester includes 3-hydroxybutyrate as a first monomer unit and includes 4-hydroxybutyrate or 3-hydroxyvalerate as a second monomer unit, the ratio of the second monomer unit to all monomer units is 1 mol% to 9 mol% when the second monomer unit is the 4-hydroxybutyrate unit, and the ratio of the second monomer unit to all monomer units is 1 mol% to 7.6 mol% when the second monomer unit is 3-hydroxyvalerate.
D01F 6/84 - Filaments, ou similaires, faits par l’homme, à un seul composant, formés de polymères synthétiquesLeur fabrication à partir de produits de copolycondensation à partir de copolyesters
13.
PULSED CURRENT DRIVE METHOD, PULSED CURRENT DRIVE STRUCTURE, CURRENT-DRIVEN MEMORY, STORAGE DEVICE, AND MEMORY CONTROL CIRCUIT
A pulsed current drive method according to the present invention involves applying a pulsed current to invert ferroelectric polarization generated by the order and imbalance of ions that have different valences.
H10B 53/30 - Dispositifs RAM ferro-électrique [FeRAM] comprenant des condensateurs ferro-électriques de mémoire caractérisés par la région noyau de mémoire
C04B 35/40 - Produits céramiques mis en forme, caractérisés par leur compositionCompositions céramiquesTraitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base de ferrites avec des oxydes de terres rares
G11C 11/22 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments électriques utilisant des éléments ferro-électriques
MITSUBISHI HEAVY INDUSTRIES MACHINERY SYSTEMS, LTD. (Japon)
THE UNIVERSITY OF TOKYO (Japon)
Inventeur(s)
Takakuwa, Yoshinao
Takahashi, Kunio
Iehara, Masato
Kamijo, Shunsuke
Shiotsuka, Daiki
Javanmardi, Ehsan
Abrégé
An image processing algorithm evaluating apparatus includes: an image storage unit that stores a plurality of actual images captured from a vehicle; an image generating unit that acquires a target image, when receiving disturbance information representing a disturbance in the target image from among the plurality of actual images stored in the image storage unit, interprets the target image, and generates a composite image by manipulating the target image in such a manner that the disturbance is reflected to the target image based on the interpretation; and an image processing unit that evaluates performance of an image processing algorithm for determining a situation around the vehicle based on the generated composite image.
G06V 10/776 - ValidationÉvaluation des performances
G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
G06V 20/56 - Contexte ou environnement de l’image à l’extérieur d’un véhicule à partir de capteurs embarqués
15.
VERTICAL DIODE AND METHOD FOR MANUFACTURING VERTICAL DIODE
Provided is a vertical diode in which a first electrode, an organic semiconductor layer, and a second electrode are laminated adjacently in the stated order, wherein low-molecular hydrophobic ions are attached to the surface of the first electrode adjacent to the organic semiconductor layer.
This magnetic sensor includes: a topological semimetal; a ferromagnetic body which is joined to the topological semimetal; and a measurement device for measuring a magnetic field on the basis of a voltage due to an odd-parity magnetoresistance effect generated in the topological semimetal.
G01R 33/09 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs galvano-magnétiques des dispositifs magnéto-résistifs
MITSUBISHI HEAVY INDUSTRIES MACHINERY SYSTEMS, LTD. (Japon)
THE UNIVERSITY OF TOKYO (Japon)
Inventeur(s)
Shimizu, Hirokazu
Nishimori, Toshiaki
Nakao, Kenta
Kamijo, Shunsuke
Lee, Jinho
Abrégé
The present invention comprises: a data storage unit that stores a plurality of radio wave distance measurement data items detected from a vehicle; a data generation unit that, when external disturbance information indicating an external disturbance to target data among the plurality of radio wave distance measurement data items stored in the storage unit is inputted, acquires and understands the target data, and generates synthesized data by working, on the basis of the understanding, the target data so that the external disturbance is reflected in the target data; and a data processing unit that evaluates, on the basis of the generated synthesized data, the performance of a data processing algorithm for determining the condition of the vehicle.
[Problem] To provide an information processing system and the like capable of facilitating the enhancement of accuracy in the estimation result of the QOL of a user. [Solution] One aspect of the present invention provides an information processing system comprising a processor, wherein the processor: in a first acquisition step, acquires correlation information having a correlation with the quality of life (QOL) of a user, the correlation information including two or more types of information that can be acquired in association with an operation at the time of utterance of the user; and, in a first output step, outputs a score indicating the QOL of the user on the basis of the acquired correlation information.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G10L 15/10 - Classement ou recherche de la parole utilisant des mesures de distance ou de distorsion entre la parole inconnue et les gabarits de référence
G10L 15/22 - Procédures utilisées pendant le processus de reconnaissance de la parole, p. ex. dialogue homme-machine
G10L 25/66 - Techniques d'analyse de la parole ou de la voix qui ne se limitent pas à un seul des groupes spécialement adaptées pour un usage particulier pour comparaison ou différentiation pour extraire des paramètres en rapport avec l’état de santé
G16H 20/70 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mentales, p. ex. la thérapie psychologique ou le training autogène
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (Japon)
JICHI MEDICAL UNIVERSITY (Japon)
NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (Japon)
Inventeur(s)
Nureki Osamu
Nakagawa Ryoya
Omura Satoshi
Kise Yoshiaki
Hoshino Atsushi
Hino Tomohiro
Matoba Satoaki
Ohmori Tsukasa
Saika Hiroaki
Toki Seiichi
Ishibashi Kazuhiro
Abrégé
The present invention provides an engineered protein that can be utilized as a genome engineering tool. The protein comprises the amino acid sequence represented by SEQ ID NO: 1 in which amino acid at position 188 is substituted with histidine, the amino acid sequence further including one selected from: substitution of amino acid at position 2 with tyrosine; substitution of amino acid at position 70 with tyrosine; substitution of amino acid at position 80 with arginine; substitution of amino acid at position 105 with threonine; substitution of amino acid at position 123 with histidine; substitution of amino acid at position 195 with lysine; substitution of amino acid at position 208 with arginine; substitution of amino acid at position 232 with alanine; substitution of amino acid at position 246 with methionine; substitution of amino acid at position 316 with methionine; and substitution of amino acid at position 337 with isoleucine.
NN generated in the thermoelectric conversion section 202 due to the heat flow H input to the thermoelectric conversion section 202 from the outside along the first direction.
NIPPON TELEGRAPH AND TELEPHONE CORPORATION (Japon)
THE UNIVERSITY OF TOKYO (Japon)
Inventeur(s)
Wada Masaki
Matsui Takashi
Iida Hiroyuki
Nakajima Kazuhide
Murayama Hideaki
Wada Ryota
Abrégé
Provided are a measurement system, a measurement method, and an analysis device that are capable of easily improving accuracy in measuring the shape of a linear structure. This measurement system for measuring the shape of a linear structure comprises a strain distribution measurement device 4 that, using a multicore optical fiber fixed along the extension direction of the linear structure, measures strain distributions that follow in the extension direction of the multicore optical fiber at two different timings or measures the difference between the strain distributions; and an analysis device 5 for calculating the shape of the multicore optical fiber using the difference between the strain distributions measured at two different timings and calculating the shape of the linear structure on the basis of the shape of the multicore optical fiber.
G01B 11/16 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la déformation dans un solide, p. ex. indicateur optique de déformation
One embodiment of the present disclosure provides a method for measuring a biomolecule. This method comprises: providing a recognition unit that includes a conductive polymer and a molecular recognition pH indicator acting as a dopant for the conductive polymer and recognizing a target biomolecule; introducing a sample containing the target biomolecule into the recognition unit; measuring the electrical characteristics of the conductive polymer, on the basis of a reaction between the target biomolecule and the molecular recognition pH indicator which occurs when the target biomolecule is introduced; and determining the amount of the target biomolecule in the sample, on the basis of the measured electrical characteristics.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
23.
TOUGHENING OF SILICONE-BASED POLYMER MATERIAL WITH ADDITION OF POLYROTAXANE
Provided is a composition which contains a silicone-based polymer material and a plurality of polyrotaxanes, wherein: each polyrotaxane has a plurality of cyclic molecules and a chain polymer that penetrates through openings of the plurality of cyclic molecules; and a polysiloxane chain is bonded to at least some of the plurality of cyclic molecules.
C07H 17/00 - Composés contenant des radicaux hétérocycliques liés directement à des hétéro-atomes de radicaux saccharide
A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à quatre chaînons, p. ex. taxol
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61K 31/706 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'azote comme hétéro-atome d'un cycle, p. ex. nucléosides, nucléotides contenant des cycles à six chaînons avec l'azote comme hétéro-atome d'un cycle
A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
C07H 17/08 - Hétérocycles d'au moins huit chaînons, p. ex. érythromycines
C07K 5/068 - Dipeptides la chaîne latérale du premier amino-acide contenant plus de groupes amino que de groupes carboxyle, ou leurs dérivés, p. ex. Lys, Arg
25.
METHOD FOR PRODUCING FIBER-REINFORCED COMPOSITE MATERIAL
This method for producing a fiber-reinforced composite material involves: introducing, into an atmosphere-controllable reaction furnace, reinforcing fiber fabric including reinforcing fibers interwoven with each other and including voids having an aspect ratio of 35 or more between the reinforcing fibers; flowing a raw material gas including hydrogen and methyltrichlorosilane into the reaction furnace; and heating the reaction furnace so as to keep at least the reinforcing fiber fabric at a temperature exceeding 1000°C but not exceeding 1100°C while maintaining the reaction furnace at a pressure lower than atmospheric pressure to cause a reaction to form a coating film including silicon carbide in the voids, thereby bonding the reinforcing fibers to each other with the coating film.
HUN-REN WIGNER RESEARCH CENTRE FOR PHYSICS (Hongrie)
Inventeur(s)
Tanaka,hiroyuki
Varga,dezso
Abrégé
Provided is a positioning system capable of performing positioning stably with high accuracy by using lightweight equipment. This positioning system includes a reference detector, a reception detector, a communication means for performing communication between the reference detector and the reception detector, and a calculation unit. The reference detector and the reception detector are each configured to detect a zenith angle and an azimuth angle of incident muons. The calculation unit is configured to calculate a relative position of the reception detector relative to the reference detector on the basis of at least the zenith angle and the azimuth angle. The reference detector and the reception detector each include an internal clock in which time points at which the muons are incident are continuously recorded. The calculation unit is further configured to synchronize the internal clocks of the reference detector and the reception detector on the basis of the continuously recorded time information.
Provided is a compound semiconductor chip that makes it possible to eliminate or reduce generation of BPD in an edge termination region of the compound semiconductor chip, and improve long-term reliability of a power device. A porous layer 13 is formed in the edge termination region 12 of a SiC chip 10, and thus generation of BPD in the edge termination region 12 can be eliminated or reduced. Particularly, in the power device, it is possible to eliminate or suppress a phenomenon in which, when a large current is made to flow in the thickness direction, the BPD of the region 12 is expanded and a stacking fault is generated by a thermal stress when the device is heated to a high temperature due to resistance heat generation by energization and then returns to a normal temperature. Further, by removing the porous layer 13, which is fragile and easy to process as compared with a bulk, it is possible to realize a smooth chip having no defects in a peripheral side portion thereof.
H01L 21/301 - Traitement des corps semi-conducteurs en utilisant des procédés ou des appareils non couverts par les groupes pour subdiviser un corps semi-conducteur en parties distinctes, p. ex. cloisonnement en zones séparées
[Problem] To provide a pressure sensor having a thin film form and flexibility, in particular, to provide a multi-point three-axis pressure sensor capable of detecting a pressure distribution in three axial directions. [Solution] The present invention comprises: a porous rubber layer 100 having a first main surface 101 and a second main surface 102; a light irradiation layer provided on the first main surface; and a light detection layer provided on the second main surface. The porous rubber layer is irradiated with a spot-like light along a direction from the first main surface toward the second main surface. A pressure applied to the porous rubber layer is measured on the basis of an intensity distribution, on the second main surface, of the spot-like light irradiated on the first main surface which changes according to the pressure applied to the porous rubber layer.
G01L 1/24 - Mesure des forces ou des contraintes, en général en mesurant les variations des propriétés optiques du matériau quand il est soumis à une contrainte, p. ex. par l'analyse des contraintes par photo-élasticité
G01L 1/00 - Mesure des forces ou des contraintes, en général
G01L 5/00 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques
G01L 5/166 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques pour la mesure de plusieurs composantes de la force en utilisant des moyens photoélectriques
The present invention provides a starting material complex for forming a metal thin film, the starting material complex having a central metal and a ligand that is coordinated to the central metal, wherein (i) the central metal has an atomic polarizability of 45 to 51, and satisfies the following conditions: polarization volume ≤ 200 and relative dielectric constant ≤ 2.20, or (ii) the central metal has an atomic polarizability of 52 to 90, and satisfies the following conditions: polarization volume ≤ 240 and relative dielectric constant ≤ 2.50.
C23C 16/18 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le dépôt d'un matériau métallique à partir de composés organométalliques
C23C 16/16 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le dépôt d'un matériau métallique à partir de métaux carbonyles
H10D 64/60 - Électrodes caractérisées par leurs matériaux
30.
CELL-ADHESIVE COMPOSITION AND POLYMER-COATED MICROPARTICLES
[Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity.
[Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity.
[Solution]A cell-adhesive composition according to the present invention includes an oxyethylene chain-containing polymer represented by the following general formula (1):
[Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity.
[Solution]A cell-adhesive composition according to the present invention includes an oxyethylene chain-containing polymer represented by the following general formula (1):
[Problem] Provided is a cell-adhesive composition including an oxyethylene chain-containing polymer having excellent biocompatibility and excellent reactivity.
[Solution]A cell-adhesive composition according to the present invention includes an oxyethylene chain-containing polymer represented by the following general formula (1):
(wherein, in the general formula (1), R1 is —(CH2)p—SH, —(CH2)p—N3, —(CH2)p—NH2, or —(CH2)p—COOH, and p is an integer of 1 to 5; R2 to R4 are each independently hydrogen or a C1-10 alkyl group; R5 is a C1-10 alkyl group; R6 is hydrogen or a C1-5 alkyl group; R7 is a C1-10 alkyl group; n is an integer of 5 to 1000; m is an integer of 1 to 10; and q is an integer of 0 to 5).
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
A power supply apparatus includes a power reception coil mounted to a moving object, a plurality of relay coils, and a power reception circuit connected with the power reception coil. The relay coils are configured to successively relay supply of electric power from a power transmission coil, which is arranged along a surface on which the moving object moves, to the power reception coil during movement of the moving object. Each of the relay coils includes a first coil and a second coil, which are configured to be magnetic-field-coupled respectively to the power transmission coil and the power reception coil, and a connection circuit that connects the first and second coils. The connection circuit includes at least one resonance capacitor involved in setting of a resonance frequency of at least one of the first and second coils. The at least one resonance capacitor has a parallel characteristic.
B60L 53/30 - Détails de construction des stations de charge
H02J 50/00 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 50/50 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant des répéteurs d’énergie supplémentaires entre les dispositifs de transmission et les dispositifs de réception
Provided is a robot arm capable of constructing a platform for work. This robot arm comprises a base 1, a first arm 2 that is rotatably connected to the base 1 at a first joint part, and a second arm 3 that is rotatably connected to the first arm 2 at a second joint part, wherein: the first arm 2 is capable of moving in a length direction of the first arm 2 with respect to the first joint part; the second arm 3 is capable of moving in a length direction of the second arm 3 with respect to the second joint part; and the robot arm can transform between a first orientation, in which the base 1, the first arm 2, and the second arm 3 are superimposed, and a second orientation, in which the first arm 2 extends in a vertical direction with respect to the base 1 and the second arm 3 is positioned at a lower end of the first arm 2 and extends in a horizontal or inclined manner.
B25J 9/06 - Manipulateurs à commande programmée caractérisés par des bras à articulations multiples
B25J 5/04 - Manipulateurs montés sur roues ou sur support mobile se déplaçant le long d'un chemin de guidage dans lequel le chemin de guidage est aussi mobile, p. ex. du type pont roulant
E01D 22/00 - Procédés ou appareils pour réparer ou renforcer les ponts existants
33.
COMPOUND HAVING ANTI-ENTAMOEBA HISTOLYTICA ACTIVITY
NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (Japon)
THE UNIVERSITY OF TOKYO (Japon)
SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION (Japon)
NAGOYA INSTITUTE OF TECHNOLOGY (Japon)
Inventeur(s)
Tsunematsu, Yuta
Nozaki, Tomoyoshi
Mori, Mihoko
Shizu, Ryota
Sumii, Yuji
Shibata, Norio
Nakano, Yumiko
Abrégé
Provided is a compound having anti-Entamoeba histolytica activity. The present invention is a compound represented by general formula (1), a salt thereof, or a solvate thereof.
C07D 303/16 - Composés contenant des cycles oxirane avec des radicaux hydrocarbonés, substitués par des atomes d'oxygène liés par des liaisons simples ou doubles par des radicaux hydroxyle estérifiés
A61K 31/336 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p. ex. fungichromine ayant des cycles à trois chaînons, p. ex. oxirane, fumagilline
A61K 31/4427 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques
C07D 303/14 - Composés contenant des cycles oxirane avec des radicaux hydrocarbonés, substitués par des atomes d'oxygène liés par des liaisons simples ou doubles par des radicaux hydroxyle libres
C07D 405/14 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
[Problem] To provide an ultrasonic probe with which monitoring can be performed continuously for a long period of time. [Solution] This ultrasonic probe is formed by comprising: a lower fabric on which an electrode and a wiring are printed; an upper fabric on which an electrode and a wiring are printed; and one or more ultrasonic elements that are provided between the lower fabric and the upper fabric and are electrically connected to the electrode printed on the lower fabric and the electrode printed on the upper fabric. The electrode and the wiring printed on the lower fabric are provided so as to fill gaps between fibers of the lower fabric.
[Problem] To provide a method for manufacturing a thin film having further reduced resistivity. [Solution] A method for manufacturing a thin film, the method comprising: a deposition process for depositing a raw material compound on a substrate by an atomic layer deposition method using the raw material compound; and a film formation process for forming a thin film by reducing the raw material compound with a reducing gas at a pressure of at least 4.5 Torr after the deposition process.
C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
C23C 16/16 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le dépôt d'un matériau métallique à partir de métaux carbonyles
C23C 16/18 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le dépôt d'un matériau métallique à partir de composés organométalliques
C23C 16/448 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c.-à-d. procédés de dépôt chimique en phase vapeur [CVD] caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour produire des courants de gaz réactifs, p. ex. par évaporation ou par sublimation de matériaux précurseurs
H01L 21/285 - Dépôt de matériaux conducteurs ou isolants pour les électrodes à partir d'un gaz ou d'une vapeur, p. ex. condensation
H01L 21/3205 - Dépôt de couches non isolantes, p. ex. conductrices ou résistives, sur des couches isolantesPost-traitement de ces couches
H01L 21/768 - Fixation d'interconnexions servant à conduire le courant entre des composants distincts à l'intérieur du dispositif
H01L 23/532 - Dispositions pour conduire le courant électrique à l'intérieur du dispositif pendant son fonctionnement, d'un composant à un autre comprenant des interconnexions externes formées d'une structure multicouche de couches conductrices et isolantes inséparables du corps semi-conducteur sur lequel elles ont été déposées caractérisées par les matériaux
H10D 64/60 - Électrodes caractérisées par leurs matériaux
36.
IL-23 SPECIFIC ANTIBODIES FOR THE TREATMENT OF SYSTEMIC SCLEROSIS
A method of treating systemic sclerosis in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial dose and subsequent doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.
A61P 37/06 - Immunosuppresseurs, p. ex. médicaments pour le traitement du rejet de greffe
C07K 16/24 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des cytokines, des lymphokines ou des interférons
A detection device includes a photodiode, and a thin-film transistor coupled to the photodiode. The thin-film transistor includes a semiconductor layer between a light-blocking layer and the photodiode, and an electrode layer between the semiconductor layer and the photodiode, and the electric layer includes a source electrode and a drain electrode of the thin-film transistor. The source electrode extends to a position facing the light-blocking layer with the semiconductor layer interposed therebetween.
This management device according to one embodiment comprises a green degree calculation unit. The green degree calculation unit calculates, as a green degree expressing the environmental contribution of hydrogen, the ratio of a renewable energy power amount to a power amount supplied only to a water electrolysis cell for generating hydrogen by water electrolysis using the supplied power. The green degree calculation unit outputs the green degree.
The present invention addresses the problem of providing an anti-tumor immune response activator which inhibits an immune checkpoint function based on interaction between VSIG4 and Siglec-7, achieves an antibody having antitumor activity, and includes the antibody as an active ingredient. The present invention provides an anti-tumor immune response activator comprising an antibody that inhibits intermolecular interaction between VSIG4 and Siglec-7 or a functional fragment thereof.
NIPPON TELEGRAPH AND TELEPHONE CORPORATION (Japon)
THE UNIVERSITY OF TOKYO (Japon)
Inventeur(s)
Hanzawa, Nobutomo
Nakajima, Kazuhide
Matsui, Takashi
Murayama, Hideaki
Wada, Ryota
Kobayahsi, Makito
Abrégé
The present disclosure is a shape measurement system including: a multi-core optical fiber in which four or more cores are disposed in a part other than the center of a cross section; a strain distribution measurement device configured to measure a strain distribution of each of the cores in a longitudinal direction of the multi-core optical fiber; and an analysis device configured to calculate a shape of the multi-core optical fiber by using the strain distribution of the multi-core optical fiber.
G01B 11/16 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la déformation dans un solide, p. ex. indicateur optique de déformation
It is an object of the present invention to provide a preventive agent, a therapeutic agent or a therapeutic composition for steatohepatitis developed by phospholipid deficiency or decreased phospholipid synthesis in the liver, and to provide a therapeutic method for the aforementioned disease. More specifically, the present invention relates to a therapeutic agent for steatohepatitis, comprising, as an active ingredient, choline or a choline metabolite, ethanolamine or an ethanolamine metabolite, a salt thereof, or a solvate thereof, wherein the therapeutic agent for steatohepatitis is characterized in that the steatohepatitis is developed by decreased phospholipid synthesis in the liver. Examples of the choline metabolite may include betaine, dimethylglycine, and phosphatidylcholine.
A61K 31/14 - Composés d'ammonium quaternaire, p. ex. édrophonium, choline
A61K 31/197 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino les groupes amino et carboxyle étant liés à la même chaîne carbone acyclique, p. ex. acide gamma-aminobutyrique [GABA], bêta-alanine, acide epsilon-aminocaproïque ou acide pantothénique
A61K 31/205 - Sels d'addition d'acides organiques avec des aminesSels d'ammonium quaternaire internes, p. ex. bétaïne, carnitine
A61K 31/685 - Diesters d'acide du phosphore avec deux composés hydroxyle, p. ex. phosphatidylinositols un des composés hydroxylés ayant des atomes d'azote, p. ex. phosphatidylsérine, lécithine
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
B60L 15/20 - Procédés, circuits ou dispositifs pour commander la propulsion des véhicules à traction électrique, p. ex. commande de la vitesse des moteurs de traction en vue de réaliser des performances désiréesAdaptation sur les véhicules à traction électrique de l'installation de commande à distance à partir d'un endroit fixe, de différents endroits du véhicule ou de différents véhicules d'un même train pour la commande du véhicule ou de son moteur en vue de réaliser des performances désirées, p. ex. vitesse, couple, variation programmée de la vitesse
B60W 30/00 - Fonctions des systèmes d'aide à la conduite des véhicules routiers non liées à la commande d'un sous-ensemble particulier, p. ex. de systèmes comportant la commande conjuguée de plusieurs sous-ensembles du véhicule
43.
METHOD FOR ANALYZING STRUCTURAL VARIATION, PRIMER PAIR SET, AND METHOD FOR DESIGNING PRIMER PAIR SET
An analysis method suitable for each SV is provided by utilizing a structural characteristic of the SV. The analysis method is a method for analyzing the presence/absence of a specific structural variation in a sample DNA including a genomic DNA, a free DNA, or a complementary DNA derived from a subject, and including a detection step of detecting the presence/absence of the specific structural variation by performing PCR using the sample DNA as a template, and using, as a primer, a primer pair set consisting of a first primer pair and a second primer pair.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
B60L 15/20 - Procédés, circuits ou dispositifs pour commander la propulsion des véhicules à traction électrique, p. ex. commande de la vitesse des moteurs de traction en vue de réaliser des performances désiréesAdaptation sur les véhicules à traction électrique de l'installation de commande à distance à partir d'un endroit fixe, de différents endroits du véhicule ou de différents véhicules d'un même train pour la commande du véhicule ou de son moteur en vue de réaliser des performances désirées, p. ex. vitesse, couple, variation programmée de la vitesse
B60W 30/00 - Fonctions des systèmes d'aide à la conduite des véhicules routiers non liées à la commande d'un sous-ensemble particulier, p. ex. de systèmes comportant la commande conjuguée de plusieurs sous-ensembles du véhicule
B60L 15/20 - Procédés, circuits ou dispositifs pour commander la propulsion des véhicules à traction électrique, p. ex. commande de la vitesse des moteurs de traction en vue de réaliser des performances désiréesAdaptation sur les véhicules à traction électrique de l'installation de commande à distance à partir d'un endroit fixe, de différents endroits du véhicule ou de différents véhicules d'un même train pour la commande du véhicule ou de son moteur en vue de réaliser des performances désirées, p. ex. vitesse, couple, variation programmée de la vitesse
B60W 30/00 - Fonctions des systèmes d'aide à la conduite des véhicules routiers non liées à la commande d'un sous-ensemble particulier, p. ex. de systèmes comportant la commande conjuguée de plusieurs sous-ensembles du véhicule
The present invention provides a method and a device for dicing an SiC wafer which: make it unnecessary to adjust the focal point of laser light; make it possible to perform dicing at the cut width as designed with the wafer cut surface vertical; prevent BPD expansion and/or cracks in a wafer cut section due to mechanical stress and/or thermal stress during dicing; prevent burning of the wafer cut surface; and make it possible to reduce residual debris on the wafer surface. Water guide laser processing is adopted in which, during dicing of an SiC wafer W, laser light R is allowed to pass through a high-pressure water beam 12, and the SiC wafer W is cut with the laser light R totally reflected by the inner wall of the water flow. Thus, it is unnecessary to adjust the focal point of the laser light R, it is possible to perform dicing at the cut width as designed with the wafer cut surface vertical, BPD expansion and/or cracks in a wafer cut section due to mechanical stress and/or thermal stress during dicing is/are prevented, burning of the wafer cut surface is prevented, and it is possible to reduce residual debris on the wafer surface.
H01L 21/301 - Traitement des corps semi-conducteurs en utilisant des procédés ou des appareils non couverts par les groupes pour subdiviser un corps semi-conducteur en parties distinctes, p. ex. cloisonnement en zones séparées
B23K 26/38 - Enlèvement de matière par perçage ou découpage
B23K 26/142 - Travail par rayon laser, p. ex. soudage, découpage ou perçage en utilisant un écoulement de fluide, p. ex. un jet de gaz, associé au faisceau laserBuses à cet effet pour l'enlèvement de résidus
B23K 26/146 - Travail par rayon laser, p. ex. soudage, découpage ou perçage en utilisant un écoulement de fluide, p. ex. un jet de gaz, associé au faisceau laserBuses à cet effet l'écoulement de fluide contenant un liquide
47.
NOVEL HVEM-BINDING PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
The purpose of the present invention is to provide a novel HVEM-binding protein. The present invention provides a human HVEM-binding protein comprising at least one immunoglobulin single variable region, wherein: the immunoglobulin single variable region includes complementarity determining regions 1-3 which have the amino acid sequence of SEQ ID NO: 1, the amino acid sequence of SEQ ID NO: 2, and the amino acid sequence of SEQ ID NO: 3, respectively; and the immunoglobulin single variable region is a humanized VHH. The protein according to the present invention may further comprise a human immunoglobulin Fc region or a human serum albumin-binding protein, and the immunoglobulin Fc region may be an Fc region of human IgG4.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 45/00 - Préparations médicinales contenant des ingrédients actifs non prévus dans les groupes
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
According to the present disclosure, a recovery efficiency of Li from a recovery object such as a used lithium ion secondary battery can be improved. The manufacture method disclosed herein includes a preparation step S11 of preparing a recovery object containing at least Li, and a chlorination heating step S12 of heating the recovery object together with a non-metal chlorine compound to produce LiCl. Since LiCl is soluble in water, Li can be easily recovered from the recovery object. That means, the technology disclosed herein makes it possible to separate Li from the recovery object immediately after the chlorination heating step S12, contributing to significant improvement of Li recovery efficiency.
C22B 3/00 - Extraction de composés métalliques par voie humide à partir de minerais ou de concentrés
C22B 7/00 - Mise en œuvre de matériaux autres que des minerais, p. ex. des rognures, pour produire des métaux non ferreux ou leurs composés
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 10/54 - Récupération des parties utiles des accumulateurs usagés
49.
PHOTOELECTRIC CONVERSION ELEMENT AND MANUFACTURING METHOD OF PHOTOELECTRIC CONVERSION ELEMENT
A photoelectric conversion element includes a light absorbing layer, a hole transport layer that transports holes generated by photoexcitation of the light absorbing layer, and a transparent conductive layer that is in contact with the hole transport layer and receives holes from the hole transport layer. The carrier density of the transparent conductive layer is more than 1×1016 cm−3 and 1×1020 cm−3 or less.
H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
H10K 30/57 - Dispositifs photovoltaïques [PV] comprenant des jonctions multiples, p. ex. des cellules PV en tandem
H10K 30/86 - Couches à haute mobilité des trous, p. ex. de transport des trous ou couches de blocage des électrons
An information processing device 1 obtains a range of values for a manipulated variable corresponding to a minimum constraint as a minimum solution set range, and sets a solution set range in which the range of solutions is limited inward of the minimum solution set range by a distance D determined by a ratio for the distance between an ideal value for the constraint and a value corresponding to the minimum constraint. The information processing device 1 then presents the solution set range, which is a restricted range of values for the manipulated variable.
G06Q 10/04 - Prévision ou optimisation spécialement adaptées à des fins administratives ou de gestion, p. ex. programmation linéaire ou "problème d’optimisation des stocks"
A manufacturing method disclosed herein includes a preparing step of preparing a collection target containing at least one of Ni and Co as a valuable metal, a heating step of heating the collection target at 500° C. or more so that at least a part of the valuable metal is reduced to a state of a metal simple substance, and an ammonia leaching step of immersing the collection target after the heating step in an ammonia aqueous solution in which ammonia, a pH buffer, and an oxidant are mixed, thereby obtaining a metal solution including the valuable metal.
H01M 4/02 - Électrodes composées d'un ou comprenant un matériau actif
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p. ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
A manufacture method disclosed herein includes: a preparation step S11 of preparing a recovery object; a measurement step S12 of measuring a quantity of oxygen element and a reducing component contained in the recovery object; a determination step S13 of determining whether or not a quantity ratio of the reducing component relative to oxygen element is higher than or equal to a threshold value based on a stoichiometric ratio of an oxide of the reducing component; a reducing component addition step S14 of adding the reducing component to the recovery object when a determined result value in the determination step is lower than the threshold value; and a heating step S15 of heating the recovery object under an inert atmosphere. This method makes it possible to reduce the valuable metal into an elemental metal, and therefore a valuable metal recovery efficiency can be improved.
The manufacture method disclosed herein includes: a preparation step of preparing a recovery object containing lithium and a first metal element; a chlorination heating step of heating the recovery object together with a metal chloride to produce LiCl; and a water dissolution step of immersing the recovery object after the chlorination heating step in water to dissolve LiCl in water to obtain a Li solution. In the manufacture method disclosed herein, a heating temperature in the chlorination heating step is 1000° C. or lower, and the metal chloride contains a second metal element that is more easily chlorinated than the first metal element in the recovered object and more hardly chlorinated than lithium in the chlorination heating step. Thereby, Li can be easily recovered from the recovery object at a low temperature of 1000° C. or lower.
C22B 3/38 - Traitement ou purification de solutions, p. ex. de solutions obtenues par lixiviation par extraction liquide-liquide utilisant des composés organiques contenant du phosphore
C22B 3/44 - Traitement ou purification de solutions, p. ex. de solutions obtenues par lixiviation par des procédés chimiques
C22B 7/00 - Mise en œuvre de matériaux autres que des minerais, p. ex. des rognures, pour produire des métaux non ferreux ou leurs composés
C22B 23/02 - Obtention du nickel ou du cobalt par voie sèche
An information processing system is provided. This information processing system is equipped with an acquisition unit, a derivation unit, a detection unit and a generation unit. The acquisition unit acquires a first image sequence which expresses a change in membrane potential in biological tissue. The derivation unit derives a second image sequence which expresses a change in membrane potential by using a circulation variable on the basis of the first image sequence and a first derivation formula. The detection unit detects the position in the biological tissue at which the focal excitation wave is produced on the basis of the second image sequence and a first detection formula. The generation unit generates position information pertaining to the production position.
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
56.
Gd-Co-BASED METALLIC POWDER, METHOD FOR PRODUCING SAME, ELECTROCONDUCTIVE MOLDED BODY, AND THERMOELECTRIC CONVERSION ELEMENT
B22F 1/00 - Poudres métalliquesTraitement des poudres métalliques, p. ex. en vue de faciliter leur mise en œuvre ou d'améliorer leurs propriétés
B22F 1/05 - Poudres métalliques caractérisées par la dimension ou la surface spécifique des particules
B22F 9/04 - Fabrication des poudres métalliques ou de leurs suspensionsAppareils ou dispositifs spécialement adaptés à cet effet par des procédés physiques à partir d'un matériau solide, p. ex. par broyage, meulage ou écrasement à la meule
Provided are: cellulose porous particles which have large surface areas on which cells can be attached, and on which cells can be adhered easily, and which rarely undergo the detachment of cells when the cells are cultured at a high density; and a microcarrier for culture use, which comprises the cellulose porous particles. The cellulose porous particles according to the present invention are composed of cellulose, in which the cellulose constituting the cellulose porous particles is modified by a cationic substituent and the cellulose constituting the celluose porous particles has a polypeptide bound thereto.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p. ex. lignées cellulairesTissusLeur culture ou conservationMilieux de culture à cet effet
The purpose of this invention is to provide an anti-adhesion material having a high anti-adhesion effect, pertaining to an anti-adhesion material comprising a biocompatible sponge-like layered body having a sponge-like first layer and a sponge-like second layer both being at least partially crosslinked with a curing agent and comprising a low endotoxin monovalent metal salt of alginic acid. The monovalent metal salt of alginic acid in the first layer has a weight average molecular weight of 30000 to 300000. The monovalent metal salt of alginic acid in the second layer has a weight average molecular weight of 1000 to 200000. The weight average molecular weights are determined by GPC-MALS after a de-crosslinking treatment. The weight average molecular weight of the monovalent metal salt of alginic acid in the first layer is higher than the weight average molecular weight of the monovalent metal salt of alginic acid in the second layer.
A polymer gel includes a structure derived from a main monomer M1, a crosslinking agent monomer M2, and a radical polymerization initiator I as a constituent element. A monomer reactivity ratio r1 of the main monomer M1 and the monomer reactivity ratio r2 of the crosslinking agent monomer M2 satisfy a condition of r1>r2, a molar ratio of an addition amount of the crosslinking agent monomer M2 to an addition amount of the main monomer M1 is 12% or less, an addition molar ratio CM of the crosslinking agent monomer M2 to an addition amount of the main monomer M1, and an addition molar ratio IM of the initiator to an addition amount of the main monomer M1 satisfy a condition of IM≤0.66CM+0.0017, and the radical polymerization initiator I is a compound having a chemical structure of a general formula (I).
C08F 230/02 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et contenant du phosphore, du sélénium, du tellure ou un métal contenant du phosphore
C08F 2/16 - Polymérisation en milieu non solvant en milieu aqueux
The present invention pertains to: a guide RNA having, on the 5' side of a spacer sequence, a repeat sequence that is cleaved through processing for forming a cascade complex, and not having a repeat sequence or having a sequence that is not cleaved through processing for forming a cascade complex, on the 3' side of the spacer sequence; and a type-I CRISPR-Cas system using the guide RNA.
A thermoelectric conversion element 1a comprises a first sheet 10, a thermoelectric conversion part 30, and a second sheet 20. The first sheet 10, the thermoelectric conversion part 30, and the second sheet 20 are arranged in the order of the first sheet 10, the thermoelectric conversion part 30, and the second sheet 20 in the thickness direction of the first sheet 10. The thermoelectric conversion part 30 includes a magnetic body.
Provided is a heat exchange promotion member and a heat exchanger that can improve heat transfer performance while holding down an increase in pressure drag of a fluid that exchanges heat with the heat exchange promotion member. A heat dissipation fin 14 of the present invention is a heat exchange promotion member that exchanges heat with a flowing fluid. The heat dissipation fin 14 includes a planar part 12 which is a surface substantially parallel to the fluid flowing direction and a raised part 13 that protrudes from the planar part 12 toward the fluid. The raised part 13 has a portion slanted relative to the direction in which the fluid flows, and there are a plurality of the raised parts 13 formed spaced apart from one another in the fluid flowing direction.
F28F 1/32 - Éléments tubulaires ou leurs ensembles avec moyens pour augmenter la surface de transfert de chaleur, p. ex. avec des ailettes, avec des saillies, avec des évidements ces moyens étant uniquement à l'extérieur de l'élément tubulaire et s'étendant transversalement les moyens ayant des parties engageant d'autres éléments tubulaires
F28F 1/34 - Éléments tubulaires ou leurs ensembles avec moyens pour augmenter la surface de transfert de chaleur, p. ex. avec des ailettes, avec des saillies, avec des évidements ces moyens étant uniquement à l'extérieur de l'élément tubulaire et s'étendant obliquement
There is disclosed a polymer gel including a structure derived from a main monomer M1, a crosslinking agent monomer M2, and a radical polymerization initiator I as a constituent element. In this polymer gel, a monomer reactivity ratio r1 of the main monomer M1 and a monomer reactivity ratio r2 of the crosslinking agent monomer M2 satisfy a condition of r1>r2, a molar ratio of an addition amount of the crosslinking agent monomer to an addition amount of the main monomer M1 is 1% or less, and a decomposition rate (10−7/s) of the radical polymerization initiator I at 25° C. is 25 or more. This polymer gel has properties of high strength and high viscosity.
C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique
C08F 220/36 - Esters contenant de l'azote contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle
Provided is a method for manufacturing a magnetic tunnel junction element provided with a magnetic tunnel junction layer and a metal layer in the stated order directly or indirectly on a substrate, the method comprising: a step for applying, to the metal layer, a resist composition containing a polymer that has a structural unit containing an aromatic ring; a step for exposing a resist film formed through the application step; a step for developing the exposed resist film; and a step for etching the magnetic tunnel junction layer and the metal layer using, as a mask, a resist pattern formed through the development step.
A method for manufacturing a magnetic tunnel junction element comprising a magnetic tunnel junction layer and a metal layer directly or indirectly on a substrate in this order, the method comprising: a step for forming a resist underlayer film on the metal layer; a step for forming a silicon oxide film on the resist underlayer film; and a step for forming a resist film on the silicon oxide film, wherein the resist underlayer film is formed from a resist underlayer film-forming composition containing a compound having an aromatic ring and a solvent.
G03F 7/11 - Matériaux photosensibles caractérisés par des détails de structure, p. ex. supports, couches auxiliaires avec des couches de recouvrement ou des couches intermédiaires, p. ex. couches d'ancrage
G03F 7/40 - Traitement après le dépouillement selon l'image, p. ex. émaillage
H10B 61/00 - Dispositifs de mémoire magnétique, p. ex. dispositifs RAM magnéto-résistifs [MRAM]
The present invention addresses the problem of developing oncolytic gene-modified measles viruses that do not recognize SLAM (rMV-SLAMblind and rMV-V(-)-SLAMblind), as a tool for tumor therapy. The present invention provides: a pharmaceutical composition for inducing cellular immunity against tumor cells for treatment, said pharmaceutical composition containing an oncolytic gene-modified measles virus; and a method for inducing cellular immunity against residual tumor cells in vivo or metastatic or recurrent tumor cells that could not be eliminated by direct introduction of an oncolytic gene-modified measles virus, said method comprising directly introducing an oncolytic gene-modified measles virus into tumor cells to be treated and causing cell death.
C12N 15/45 - Paramyxoviridae, p. ex. virus de la rougeole, virus des oreillons, virus de la maladie de Newcastle, virus de la maladie de Carré, virus de la peste bovine, virus respiratoires syncytiaux
Utilization of Carbon Dioxide Institute Co., Ltd. (Japon)
The University of Tokyo (Japon)
Inventeur(s)
Yukawa, Hideaki
Ohtani, Naoto
Ishii, Masaharu
Abrégé
The present disclosure provides a transformant obtained by introducing an aldehyde-alcohol dehydrogenase gene into a bacterium of the genus Hydrogenophilus.
A polymer compound in which coumarin or a derivative thereof is bonded to at least one terminal of a skeletal polymer. A flow property of the polymer compound is reversibly changeable from a first state to a second state by irradiation with light at a first wavelength and from the second state to the first state by irradiation with light at a second wavelength different from the first wavelength.
C08G 77/442 - Polymères séquencés ou greffés contenant des segments de polysiloxanes contenant des segments de polymères vinyliques
C08G 77/52 - Composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant du silicium, avec ou sans soufre, azote, oxygène ou carbone dans lesquels au moins deux atomes de silicium, mais pas la totalité, sont liés autrement que par des atomes d'oxygène par des liaisons au carbone contenant des cycles aromatiques
Disclosed is a method for evaluating the oxidation activity of a dehydrogenase, the method comprising causing the dehydrogenase and DT-diaphorase to catalyze an oxidation-reduction reaction in an aqueous solution containing one molecule of the dehydrogenase, a substrate of the dehydrogenase, a nucleoside diphosphate derivative, the DT-diaphorase, and a fluorescent probe, and measuring the fluorescence after the reaction.
C12Q 1/32 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une oxydoréductase une déshydrogénase
G01N 33/533 - Production de composés immunochimiques marqués avec un marqueur fluorescent
71.
NICOTIANA PLANT PRODUCTION METHOD AND TARGET PROTEIN MANUFACTURING METHOD
Provided is a nicotiana plant production method that requires less electricity and that improves production efficiency of a target protein. This nicotiana plant production method comprises: a step for cultivating a host nicotiana plant; a step for further cultivating the host nicotiana plant while irradiating the middle portion and the lower portion of the above-ground part of the host nicotiana plant with light (first irradiation step); a step for introducing the gene of a target protein into the host nicotiana plant (introduction step); and a step for further cultivating the nicotiana plant that has been introduced with the gene of the target protein while irradiating the middle portion and the lower portion of the above-ground part of the host nicotiana plant with light (second irradiation step).
A01H 1/00 - Procédés de modification des génotypes
A01H 5/00 - Angiospermes, c.-à-d. plantes à fleurs, caractérisées par leurs parties végétalesAngiospermes caractérisées autrement que par leur taxonomie botanique
C12N 15/00 - Techniques de mutation ou génie génétiqueADN ou ARN concernant le génie génétique, vecteurs, p. ex. plasmides, ou leur isolement, leur préparation ou leur purificationUtilisation d'hôtes pour ceux-ci
C12P 21/00 - Préparation de peptides ou de protéines
C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
The present invention pertains to hepatocytes, liver progenitor cells, cholangiocytes, liver sinusoidal endothelial progenitor cells, liver sinusoidal endothelial cells, hepatic stellate progenitor cells, hepatic stellate cells, and liver cellular tissue models, as well as to methods for preparing these cells. The present invention also pertains to a cell fraction comprising liver progenitor cells, liver sinusoidal endothelial progenitor cells, or hepatic stellate progenitor cells. The present invention also pertains to a pharmaceutical composition or kit comprising the above-mentioned cells, a liver cellular tissue model, or a cell fraction. The present invention also pertains to: a method for screening liver disease treatment agents; a method for evaluating the hepatotoxicity of drugs, hepatocytes for infectious disease models, and a method for preparing the same; infectious disease model tissues and a method for preparing the same; as well as a method for screening infectious liver disease treatment agents.
C12N 5/077 - Cellules mésenchymateuses, p. ex. cellules osseuses, cellules de cartilage, cellules stromales médulaires, cellules adipeuses ou cellules musculaires
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
73.
FLAVORING COMPOSITION FOR ENHANCING SALTY TASTE, AND REDUCED-SODIUM SEASONING AND REDUCED-SODIUM FOOD OR DRINK PRODUCED BY USING FLAVORING COMPOSITION
The present invention provides: a flavoring composition for reducing the sodium content in a food or drink without diminishing the salty taste; a reduced-sodium seasoning or a reduced-sodium food or drink produced by using the flavoring composition; and a method for producing said reduced-sodium seasoning or said reduced-sodium food or drink.
A23L 7/13 - En-cas ou similaires obtenus par friture d'une pâte de céréales façonnée
A23L 7/161 - Céréales soufflées, p. ex. maïs soufflé [pop-corn] ou riz soufflé
A23L 13/00 - Produits à base de viandeFarine de viandeLeur préparation et leur traitement
A23L 17/00 - Produits tirés de la merProduits à base de poissonFarine de poissonSuccédanés d’œufs de poissonLeur préparation ou leur traitement
A23L 23/00 - PotagesSauces Leur préparation ou leur traitement
A23L 27/00 - ÉpicesAgents aromatiques ou condimentsÉdulcorants artificielsSels de tableSubstituts diététiques du selLeur préparation ou leur traitement
A23L 33/16 - Sels inorganiques, minéraux ou oligo-éléments
74.
AROMA CHEMICAL COMPOSITION AND MENSTRUAL CYCLE MARKER
The present invention addresses the problem of: providing an aroma chemical comprising a substance secreted characteristically in the ovulatory period, the aroma chemical, as a result of smelling the fragrance thereof, evoking a pleasant feeling, inducing a tranquil effect in men, and increasing allure in women; as well as providing substances (menstrual cycle markers) for specifying each period of the menstrual cycle, and a method for estimating menstrual cycles using said substances. Specifically, the present invention is an aroma chemical composition comprising one or more compounds selected from the group of compounds consisting of geranylacetone, 9-hexadecenoic acid, and tetradecanoic acid. The present invention also is a method for estimating the menstrual cycle of a subject, the method comprising the detection, in secreted substances from the axilla of the subject, of at least one compound selected from the group of compounds consisting of: octanal; 1-tetradecanol; 1,3-butanediol; 1-hexadecanol; hexanoic acid; dodecanal; propionic acid; 2,6,10,14-tetramethyl-pentadecane; heptadecane; 1-pentadecanol; (Z)-9-octadecenoic acid; 1-dodecanol, 1-octanol; hexahydro-2H-azepin-2-one; 1-tridecanol; tetradecane; octadecane; tetradecanoic acid; (E)-geranylacetone; (Z)-9-hexadecenoic acid; hydrogen sulfide; and 2-pyrrolidone.
A61K 8/35 - Cétones, p. ex. quinones, benzophénone
A61K 8/36 - Acides carboxyliquesLeurs sels ou anhydrides
A61Q 13/00 - Formulations ou additifs pour les préparations de parfums
D06M 13/00 - Traitement des fibres, fils, filés, tissus ou articles fibreux faits de ces matières, avec des composés organiques non macromoléculairesUn tel traitement combiné avec un traitement mécanique
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
75.
PHARMACEUTICAL, FOOD, AND COSMETIC COMPOSITIONS AND PRODUCTS
A pharmaceutical composition comprising an effective amount of extracellular vesicles derived from a plant. A food composition comprising an effective amount of extracellular vesicles derived from a plant. A cosmetic composition comprising an effective amount of extracellular vesicles derived from a plant. For example, the plant is selected from the group consisting of coastal hog fennel, Madeira vine, lemongrass, green garlic, turmeric, crimson glory vine, and bitter melon.
A61K 36/23 - Apiaceae ou Umbelliferae (famille de la carotte), p. ex. aneth, cerfeuil, coriandre ou cumin
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
76.
Biomarker for Detecting Hepatocytes With Bile Ductular Proliferation
National University Corporation Kanazawa University (Japon)
Inventeur(s)
Seiki, Motoharu
Yamashita, Taro
Okada, Hikari
Kaneko, Shuichi
Koshikawa, Naohiko
Funahashi, Nobuaki
Abrégé
The present invention provides a method of detecting a biomarker for detecting hepatocytes with bile ductular proliferation, the method including: detecting laminin γ2 single chain or a nucleic acid encoding the same as the biomarker in a specimen.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
The purpose of the present invention is to manufacture a fine-patterned magnetic storage element with high precision. A magnetic storage element (1) includes: a magnetic tunnel junction layer (30) having a structure in which an insulating layer (32) is sandwiched between two magnetic layers (31) and (33), and in which the resistance state changes in accordance with the magnetization direction of one of the magnetic layer (31) and the magnetic layer (33); and a metal layer (40) provided on the magnetic tunnel junction layer (30). A method for manufacturing the magnetic storage element (1) includes a step for forming a resist film (50) having an opening (50a) on a substrate (10) on which an electrode layer (20) is formed, a step for forming a magnetic tunnel junction layer (30) on the electrode layer (20) exposed in the opening (50a), a step for forming a metal layer (40) on the magnetic tunnel junction layer (30), and a step for removing the resist film (50).
Disclosed is a method for producing a decellularized tissue or organ, the method comprising: a step for incorporating a DNA-degrading enzyme into an animal-derived tissue or organ; and a step for applying a hydrostatic pressure of 100-500 MPa in a medium that contains the DNA-degrading enzyme to the animal-derived tissue or organ into which the DNA-degrading enzyme has been incorporated.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
The present invention addresses the problem of providing: a protein that acts as a scintillator; and a method for designing a protein that acts as a scintillator. According to the present invention, a use of a β-barrel-type fluorescent protein as a scintillator is provided, wherein the β-barrel-type fluorescent protein has a fluorescence peak at 500 nm or less. According to the present invention, a method for designing a protein that acts as a scintillator is also provided, the method comprising (A) a step for identifying a specific amino acid residue in an amino acid sequence for a β-barrel-type fluorescent protein being mutated and (B) a step for constructing, on the basis of the amino acid sequence for the protein being mutated, an amino acid sequence having a structure such that the amino acid residue identified in the step (A) is substituted by another specific amino acid residue.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12N 1/13 - Algues unicellulairesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 1/15 - ChampignonsLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 1/19 - LevuresLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p. ex. cellules transformées par des virus
Provided is a technique capable of efficiently detecting chemical substances with reduced power consumption. This gas detecting system comprises: a ground-level moving body that can move along the ground; one or more flying bodies that are mounted on the ground-level moving body and that can float in the air; and a sensor that is provided on at least the one or more flying bodies to detect a chemical substance in a gas. The gas detecting system performs detection using the sensor in a first mode in which the one or more flying bodies are mounted on the ground-level moving body, and then transitions to a second mode in which the one or more flying bodies are allowed to float from the ground-level moving body, and performs detection using the sensor.
G01M 3/20 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des révélateurs particuliers, p. ex. teinture, produits fluorescents, produits radioactifs
G01M 3/02 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide
G05D 1/43 - Commande de la position ou du cap par référence à un système à deux dimensions
G05D 1/46 - Commande de la position ou du cap dans les trois dimensions
G08B 21/12 - Alarmes pour assurer la sécurité des personnes réagissant à l'émission indésirable de substances, p. ex. alarmes de pollution
B64U 101/35 - Véhicules aériens sans pilote spécialement adaptés à des utilisations ou à des applications spécifiques à la science, p. ex. à la météorologie
81.
INFORMATION PROCESSING SYSTEM AND INFORMATION PROCESSING METHOD
An information processing system has a storage unit, a determination unit, and a control unit. The storage unit stores an approximation level related to a calculation. The approximation level can be changed during execution of the calculation. During the execution of the calculation, the determination unit determines whether to carry out a first process or a second process according to a probability determined on the basis of the approximation level stored in the storage unit. The second process is an approximation process of the first process. The control unit carries out control so as to carry out the process determined by the determination unit.
H04N 23/611 - Commande des caméras ou des modules de caméras en fonction des objets reconnus les objets reconnus comprenant des parties du corps humain
A microneedle structure of the present invention comprises: a liquid-impermeable base material that has a through-hole; a liquid-absorbable absorbent material that fills the through-hole; a needle-shaped portion that is provided on one surface side of the base material and has a flow channel formed therein; and a functional member that is provided on the other surface side of the base material. The needle-shaped portion and the absorbent material are connected to each other, and the absorbent material and the functional member are connected to each other.
A61M 37/00 - Autres appareils pour introduire des agents dans le corpsPercutanisation, c.-à-d. introduction de médicaments dans le corps par diffusion à travers la peau
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
83.
SYNTHESIS OF CEFAZOLIN UNDER SEQUENTIAL CONTINUOUS-FLOW CONDITIONS
The present disclosure relates to a sequential continuous-flow synthesis of cefazolin, which is a vital first-choice drug used for the prevention of primary infection in most surgeries, was investigated. Rapid flow and efficient mixing of substrates in suitable flow reactors enabled the target compound to be obtained in a short period without any intermediate isolation. A flexible system design that can be applied from a small-scale to medium-scale synthesis could be demonstrated, and optimal parameters were established to realize the synthesis. A 0.3 mol/h scale synthesis was achieved in 54% isolated yield with 13.75 g/h dL space-time-yield of cefazolin. The obtained material had an acceptable impurity profile and could be purified by simple acid-base extraction and precipitation.
A scanning transmission electron microscope system (100) comprises: an irradiation source (102) that generates an electron beam (EB); a lens (104) that converges the electron beam (EB) toward a sample (S); a detector (106) that detects the electron beam (EB) transmitted through the sample (S), and acquires a detection signal which is a four-dimensional data set represented by a two-dimensional scan position on the sample (S) and by two-dimensional coordinates on the detector surface; and a computer (108) that performs a Fourier transform on the detection signal acquired by the detector (106) with respect to the scan position, obtains Fourier transform data of a complex number represented by a two-dimensional spatial frequency and two-dimensional coordinates, calculates, for a specific spatial frequency, the thickness of the sample (S) and the inclination of the sample (S) with respect to a prescribed direction, from the amplitude of the Fourier transform data, and calculates the aberration of the lens (104) from the phase of the Fourier transform data.
H01J 37/28 - Microscopes électroniques ou ioniquesTubes à diffraction d'électrons ou d'ions avec faisceaux de balayage
G01N 23/04 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p. ex. rayons X ou neutrons, non couvertes par les groupes , ou en transmettant la radiation à travers le matériau et formant des images des matériaux
85.
CONGESTION DEGREE MEASUREMENT DEVICE, CONGESTION DEGREE MEASUREMENT SYSTEM, CONGESTION DEGREE MEASUREMENT METHOD, AND CONGESTION DEGREE MEASUREMENT PROGRAM
A congestion degree measurement device (1) includes: a data reception unit (10) that receives wireless data based on wireless signals received by one or more wireless sensors (Sen#1 to Sen#I) at a location (9) set for receiving visitors (Gst#1 to Gst#Z); a visitor count calculation unit (20) that, on the basis of wireless data, or on the basis of permanently installed wireless terminal information acquired as information relating to the wireless data and to permanently installed wireless terminals (Dev#1 to Dev#X) for transmitting wireless signals, calculates a mobile wireless terminal count, which is the number of mobile wireless terminals (Mob#1 to Mob#Y) that are carried by the visitors (Gst#1 to Gst#Z) present at the location (9) and that transmit wireless signals, and calculates a visitor count, which is the number of visitors (Gst#1 to Gst#Z), from the mobile wireless terminal count; and a congestion degree calculation unit (30) that, on the basis of the visitor count, calculates a congestion degree indicating the degree of congestion by the visitors (Gst#1 to Gst#Z) at the location (9).
A sensor device that detects information related to a load or a torque acting on a detection object includes a plurality of sensor members that are attached to the detection object and are connected in parallel, and an estimation unit that estimates the information related to the load or the torque acting on the detection object based on detected values of the plurality of sensor members.
Provided is an oncolytic herpes simplex virus having a gene encoding an immune checkpoint inhibitor. This herpes simplex virus preferably has the following features (a)-(c). (a) The ICP6 gene is deleted or inactivated, (b) the γ34.5 gene is deleted or inactivated, and (c) the α47 gene is deleted or inactivated. Since the expressed immune checkpoint inhibitor remains at the tumor locus and does not flow out into the blood, systemic side effects are not generated.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
The present invention relates to a composition comprising a monoclonal antibody binding to Clostridium difficile (C. difficile) for inhibiting a growth of Clostridium difficile (C. difficile), and a use thereof. In addition, the present invention discloses the composition for treating an inflammatory bowel disease, and a use thereof.
NIPPON TELEGRAPH AND TELEPHONE CORPORATION (Japon)
THE UNIVERSITY OF TOKYO (Japon)
Inventeur(s)
Hanzawa, Nobutomo
Nakajima, Kazuhide
Matsui, Takashi
Murayama, Hideaki
Wada, Ryota
Abrégé
The present disclosure is a control system configured to: collect a strain distribution of an underwater structure connected to an above-water structure; and control at least one of the underwater structure and the above-water structure in accordance with the strain distribution.
Provided are: an enzyme detection method by which enzymes for synthesizing ATP or ADP can be detected, highly sensitive detection at one molecular level can be performed for an enzyme not having a fluorescent substrate among the enzymes, and highly sensitive measurement of a disease biomarker or the like can be performed; and an enzyme detection kit used in the same. Provided are an enzyme detection method for detecting, from an enzyme sample, a target enzyme for synthesizing ADP or ATP, and an enzyme detection kit used in the same, the method comprising: a sample addition step for preparing a detection device including a microchamber array member in which a plurality of storage parts capable of being filled with a detection liquid are arranged, and filling the storage parts of the detection device with a detection liquid containing the enzyme sample and a hexokinase enzyme; and a detection step for detecting, from the detection liquid, a signal obtained by synthesizing ADP or ATP.
C12Q 1/48 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une transférase
C12Q 1/26 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une oxydoréductase
C12Q 1/50 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une transférase une créatinophosphokinase
91.
COHERENT ISING MACHINE WITH OPTICAL ERROR CORRECTION FOR OPTIMIZATION SOLUTION GENERATOR SYSTEM AND METHOD
A coherent Ising machine may comprise a pump pulse generator configured to generate optical signal pulses; an optical error correction circuit configured to generate optical error pulses; and a main ring cavity configured to store the optical signal pulses and the optical error pulses, wherein the optical error pulses cause the coherent Ising machine not to converge on a local minima of Ising solution and continue to explore nearby states.
G06N 3/067 - Réalisation physique, c.-à-d. mise en œuvre matérielle de réseaux neuronaux, de neurones ou de parties de neurone utilisant des moyens optiques
G06N 3/047 - Réseaux probabilistes ou stochastiques
92.
METHOD FOR DETECTING KIDNEY DYSFUNCTION DIAGNOSTIC MARKER, METHOD FOR DETERMINING RENAL PROGNOSIS, DETECTION KIT FOR KIDNEY DYSFUNCTION DIAGNOSTIC MARKER, AND KIDNEY DYSFUNCTION DIAGNOSTIC MARKER
A method for detecting a kidney dysfunction diagnostic marker, the method including measurement of an expression amount of MUC1 and/or MGAM in urinary extracellular vesicles derived from a subject.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
A method for covering a fiber body includes an impregnation condition determination process for, at a time of carrying out a chemical vapor infiltration to cover the fiber body with a ceramic, determining an infiltration temperature and an infiltration pressure that maximizes a film growth rate of the ceramic throughout the fiber body relative to the infiltration temperature; and an infiltration step for supplying a film gas including an ingredient of the ceramic to carry out the chemical vapor infiltration at the infiltration temperature and the infiltration pressure determined in the impregnation condition determination process.
The present disclosure relates to anisotropic magnetic contrast agents containing iron oxide nanoparticles for low-field magnetic resonance scanners, to be applied in the production of morphology- free images, and/or recording/reading information in soft materials containing protons, using low-field magnetic resonance scanners.
A61K 49/18 - Préparations de contraste pour la résonance magnétique nucléaire [RMN]Préparations de contraste pour l'imagerie par résonance magnétique [IRM] caractérisées par un aspect physique particulier, p. ex. émulsions, microcapsules, liposomes
It is an object of the present invention to provide a method of reliably chemogenetically controlling the activity of a protein, and to provide a protein used in the present method. Specifically, the present invention relates to a plurality of protein fragments, which recover the activity of the protein when the plurality of protein fragments assemble, and in which each of the plurality of protein fragments is tagged with a degradation domain (DD) sequence. In addition, the present invention also relates to a method of regulating the activity of a protein in a cell, comprising: a step of introducing into a cell, a fusion of a DD sequence, and each fragment of a protein that has been split into fragments, such that the fragments recover the activity of the protein when they assemble; and a step of introducing a DD sequence-specific stabilizing factor into the cell.
A two-layer film of a magnetic body and an insulator according to the present invention comprises an antiferromagnetic layer that has a hexagonal crystal structure, with at least one surface thereof being the (10-10) plane of the antiferromagnetic body, and an insulator layer that is composed of two, three, or four kinds of atoms layered on the (10-10) plane. A two-layer film of a magnetic body and an insulator according to the present invention comprises an antiferromagnetic layer that has a hexagonal crystal structure, with at least one surface thereof being the (0001) plane of the antiferromagnetic body, and an insulator layer that is composed of two, three, or four kinds of atoms layered on the (0001) plane. A tunnel magnetoresistive element according to the present invention comprises a second antiferromagnetic film layer that is layered on the insulator of the two-layer film. A magnetic memory according to the present invention comprises a plurality of the tunnel magnetoresistive elements.
According to the present invention, the strength of a fiber sheet such as a paper is improved. A fiber sheet according to an embodiment contains cellulose fibers satisfying conditions (A) to (C), and the proportion of the cellulose fibers which satisfy (A) to (C) among all the cellulose fibers contained in the fiber sheet is 50 mass% or greater. (A) Anionic functional groups are comprised, with at least a portion of the same being salt-type. (B) The number average fiber width is 1 μm or greater. (C) When an aqueous suspension with a cellulose fiber concentration of 0.2 mass%, adjusted to 20°C, is filtered using a filter with 60 μm mesh openings, the content of the cellulose fibers in the filtrate is 0.06 mass% or less.
D21H 11/20 - Fibres modifiées chimiquement ou biochimiquement
D21H 15/02 - Pâte ou papier comprenant des fibres ou des matériaux formant des nappes caractérisés autrement que par leur constitution chimique caractérisés par leur configuration
98.
CARBON NANOTUBE MOLDED BODY, ELECTRODE FOR ELECTROCHEMICAL WATER SPLITTING AND METHOD FOR PRODUCING SAME, AND ELECTROCHEMICAL WATER SPLITTING DEVICE
Provided are: a carbon nanotube molded body containing carbon nanotubes, wherein the specific surface area of the carbon nanotube molded body is 700 m2/g or more, the pore distribution of the carbon nanotube molded body is 3-15 nm, the tensile strength of the carbon nanotube molded body is 45 MPa or more, and the Young's modulus of the carbon nanotube molded body is 1600 MPa or more; and a method for producing the carbon nanotube molded body. Also provided are: an electrode for electrochemical water splitting that contains the carbon nanotube molded body and platinum supported on the carbon nanotube molded body and a method for producing the same; and an electrochemical water splitting device provided with the electrode for electrochemical water splitting.
[Problem] To provide an information processing device, program, and pattern code that make it possible to quickly specify a position in a pattern.
[Problem] To provide an information processing device, program, and pattern code that make it possible to quickly specify a position in a pattern.
[Solution] In one embodiment of this invention, an information processing device is provided. The information processing device comprises a projection image generation unit, a decryption unit, and a phase specification unit. The projection image generation unit is configured so as to be capable of generating a projection image on the basis of predetermined pattern information and outputting the generated projection image to a projection device. The projection image comprises a clock pattern and a data pattern based on pattern information. The decryption unit is configured so as to be capable of decrypting the data pattern into values on the basis of a captured image obtained by imaging an object using an imaging device. The captured image is an image obtained by photographing the object when the projection image is being projected thereon by the projection device. The phase specification unit is configured so as to be capable of specifying the phases of each part of the object on the basis of the values and pattern information.
National Institute of Information and Communications Technology (Japon)
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japon)
The University of Tokyo (Japon)
Inventeur(s)
Yoshino, Ken-Ichiro
Fujiwara, Mikio
Tomita, Akihisa
Koashi, Masato
Takeoka, Masahiro
Abrégé
An object is to prevent eavesdropping in quantum key distribution. A synchronization signal reception device receives a synchronization signal that is an optical signal for defining a timing at which a quantum signal is detected, and outputs a reference signal corresponding to the synchronization signal. A clock signal generation unit generates a clock signal in response to the reference signal. A photon detection device detects a photon of the quantum signal in response to the clock signal. A timing of the clock signal randomly changes within a predetermined range.