Virginia Tech Intellectual Properties, Inc.

United States of America

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A61B 18/14 - Probes or electrodes therefor 45
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body 44
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1.

HYDROGEL COMPOSITIONS COMPRISING POLYMER-SALT COMPOSITES AND METHODS OF MAKING SAME

      
Application Number 18843595
Status Pending
Filing Date 2023-03-03
First Publication Date 2025-05-29
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Zanelotti, Curt J.
  • Yu, Deyang
  • Madsen, Louis A.

Abstract

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to polymer-salt composite hydrogel compositions comprising an ionic polymer material, a cationic component, and a solvent as disclosed herein. The present disclosure further pertains to the disclosed methods of making the disclosed polymer-salt composite hydrogel compositions, methods of using the disclosed polymer-salt composite hydrogel compositions, and products comprising the disclosed polymer-salt composite hydrogel compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

IPC Classes  ?

2.

NDVI AND NDRE MODELS TO DETERMINE TILLER DENSITY IN WINTER WHEAT

      
Application Number 18955434
Status Pending
Filing Date 2024-11-21
First Publication Date 2025-05-22
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Oakes, Joseph
  • Balota, Maria
  • Thomason, Wade
  • Cazenave, Alexandre-Brice

Abstract

Various embodiments for determining fertilizer application for crops based on aerial-based vegetation indices are described. In one example, a method includes determining a relationship between an aerial vegetation index for a crop and tiller density of the crop. The method further includes creating a fertilizer application model for the crop based at least in part on recommended fertilizer application data for the crop and the relationship between the aerial vegetation index and the tiller density of the crop. The recommended fertilizer application data being correlated with the tiller density of the crop.

IPC Classes  ?

  • G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
  • A01G 22/22 - Rice

3.

MICROFLUIDIC PATCH-PUMP FOR DELIVERY OF LIQUID DRUGS

      
Application Number US2024056413
Publication Number 2025/106990
Status In Force
Filing Date 2024-11-18
Publication Date 2025-05-22
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Staples, Anne
  • Davalos, Rafael, V.
  • Zhang, Shuyu

Abstract

e.g.e.g., macromolecular drugs that are difficult to deliver through an oral pathway and/or that require transdermal delivery. Embodiments are slim, powerless, painless, and relatively inexpensive. The microfluidic pump is used to drive the fluid flow powered by pressurized air or the user's pulse, and the microneedle array is used to inject the fluid through the skin painlessly. The flow rate generally positively correlates with the actuation pressure. For devices with wider flow channels, the flow rate generally negatively correlates with the actuation frequency, whereas the flow rate increases and then decreases with increasing actuation frequency for devices with narrower flow channels. This property of these devices is beneficial in insulin delivery because the demand for insulin is generally reduced in vigorous exercise (with elevated heart rate/ actuation frequency) and is increased in hypertension patients (with elevated blood/actuation pressure).

IPC Classes  ?

  • A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
  • A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin

4.

RAPID DETECTION AND ANALYSIS OF BIOLOGICAL COMPONENTS USING SURFACE ENHANCED RAMAN SPECTROSCOPY

      
Application Number 18951181
Status Pending
Filing Date 2024-11-18
First Publication Date 2025-05-22
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Garg, Aditya
  • Zhou, Wei
  • Marr, Linsey
  • Vikesland, Peter
  • Duggal, Nisha

Abstract

The present disclosure is directed to rapid detection and analysis of biological components using surface-enhanced Raman spectroscopy (SERS). One general aspect includes a method for preparing biological components from a biological sample for label-free SERS. The method also includes providing a Raman-background-free surfactant buffer to the biological sample. The method also includes agitating and heating the biological sample in the buffer to accelerate a lysis process thereby decomposing structural components of the biological sample. The structural components are substantially free of Raman background interference and are optimized for SERS signal enhancement.

IPC Classes  ?

  • G01N 21/65 - Raman scattering
  • G01N 1/44 - Sample treatment involving radiation, e.g. heat
  • G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • G16B 40/10 - Signal processing, e.g. from mass spectrometry [MS] or from PCR
  • G16B 40/20 - Supervised data analysis

5.

NUDIX OVEREXPRESSING ENGINEERED PLANTS AND USES THEREOF

      
Application Number 18730449
Status Pending
Filing Date 2023-01-19
First Publication Date 2025-05-15
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Freed, Catherine
  • Gillaspy, Glenda

Abstract

Described in several example embodiments herein are NUDIX overexpressing plants and uses thereof. In some embodiments, the NUDIX overexpressing plants are used for phytoremediation.

IPC Classes  ?

  • C12N 9/14 - Hydrolases (3.)
  • B09C 1/10 - Reclamation of contaminated soil microbiologically or by using enzymes
  • C02F 3/32 - Biological treatment of water, waste water, or sewage characterised by the animals or plants used, e.g. algae
  • C02F 101/10 - Inorganic compounds
  • C05D 9/00 - Other inorganic fertilisers
  • C10B 53/02 - Destructive distillation, specially adapted for particular solid raw materials or solid raw materials in special form of cellulose-containing material
  • C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

6.

NOVEL EXTENDED RANGE VERTICAL TAKE-OFF AND LANDING DRONE

      
Application Number 18949543
Status Pending
Filing Date 2024-11-15
First Publication Date 2025-05-15
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Kochersberger, Kevin
  • Deshmukh, Sarthak
  • Moncure, Katie Marie

Abstract

Various embodiments of a novel monocoque aerostructure quadcopter implemented as a vertical take-off and landing vehicle are described. In one example, a vertical take-off and landing vehicle includes a fuselage having a leading end positioned in a first horizontal plane and a trailing end positioned in a second horizontal plane that is vertically below the first horizontal plane. The vertical take-off and landing vehicle further includes a first arm assembly extending from the leading end of the fuselage in the first horizontal plane. The vertical take-off and landing vehicle further includes a second arm assembly extending from the trailing end of the fuselage in the second horizontal plane. The vertical take-off and landing vehicle further includes a first rotor assembly coupled to the first arm assembly and a second rotor assembly coupled to the second arm assembly.

IPC Classes  ?

  • B64U 10/20 - Vertical take-off and landing [VTOL] aircraft
  • B64F 5/10 - Manufacturing or assembling aircraft, e.g. jigs therefor
  • B64U 20/73 - Monocoque body
  • B64U 20/77 - Constructional aspects of the UAV body the body being formed integrally with wings or rotor supports
  • B64U 30/29 - Constructional aspects of rotors or rotor supportsArrangements thereof
  • B64U 50/31 - Supply or distribution of electrical power generated by photovoltaics
  • B64U 60/50 - Undercarriages with landing legs

7.

IMMUNOTHERAPEUTIC METHODS USING ELECTROPORATION

      
Application Number 19026703
Status Pending
Filing Date 2025-01-17
First Publication Date 2025-05-15
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Davalos, Rafael V.
  • Rossmeisl, John H.
  • Garcia, Paulo A.

Abstract

Methods for treating tissue with irreversible electroporation and immunotherapy are described. The methods include placing a probe in tissue within a human body, wherein the probe has at least a first electrode, applying a plurality of electrical pulses through the first electrode and a second electrode, causing irreversible electroporation (IRE) of the tissue within a target ablation zone, and administering one or more exogenous agents into the tissue within the target ablation zone or to the human, thereby stimulating or otherwise modulating an immune system response within the body.

IPC Classes  ?

  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
  • C12N 13/00 - Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

8.

SPECTRAL GRAZING AND FORAGE INTAKE MONITORING DEVICE AND USES THEREOF

      
Application Number US2024054108
Publication Number 2025/096933
Status In Force
Filing Date 2024-11-01
Publication Date 2025-05-08
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor White, Robin

Abstract

Described herein are devices, systems, and methods for determining forage intake, forage quality, and/or foraging behavior of an animal. The devices and systems of the present disclosure can also be used to determine other individual animal, herd, forage and other environmental characteristics. The device can be configured, in some embodiments, to take other measurements, such as location, speed, mastication amount, etc., which can be combined with the forage spectral data to provide further insight into grazing patterns, preferences, behaviors, and the like

IPC Classes  ?

  • G08B 5/36 - Visible signalling systems, e.g. personal calling systems, remote indication of seats occupied using electric transmissionVisible signalling systems, e.g. personal calling systems, remote indication of seats occupied using electromagnetic transmission using visible light sources
  • G06T 7/90 - Determination of colour characteristics

9.

QUASI-VERTICAL POWER DEVICE

      
Application Number 18486880
Status Pending
Filing Date 2023-10-13
First Publication Date 2025-04-17
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Zhang, Yuhao
  • Qin, Yuan

Abstract

A device may include a substrate. A device may include a first semiconductor region of a first conductivity type having a first doping concentration, the first semiconductor region including a base surface, a buffer region positioned between the substrate and the first semiconductor region. A device may include a second semiconductor region of the first conductivity type and having a second doping concentration that is less than the first doping concentration, the second semiconductor region positioned over the base surface of the first semiconductor region. A device may include at least one first device terminal positioned over the base surface of the first semiconductor region. A device may include a third semiconductor region of a second conductivity type disposed over at least one sidewall of the second semiconductor region.

IPC Classes  ?

  • H01L 29/78 - Field-effect transistors with field effect produced by an insulated gate
  • H01L 29/20 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only AIIIBV compounds
  • H01L 29/808 - Field-effect transistors with field effect produced by a PN or other rectifying junction gate with a PN junction gate
  • H01L 29/861 - Diodes

10.

METHODS OF REDUCING ADVERSE EFFECTS OF NON-THERMAL ABLATION

      
Application Number 18930252
Status Pending
Filing Date 2024-10-29
First Publication Date 2025-04-17
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Neal, Ii, Robert E.
  • Garcia, Paulo A.
  • Davalos, Rafael V.
  • Rossmeisl, John H.
  • Robertson, John L.

Abstract

The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.

IPC Classes  ?

  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
  • A61N 1/04 - Electrodes
  • C12N 13/00 - Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
  • G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

11.

CHIP-INTEGRATED NANOLAMINATE NANO-OPTOELECTRODE ARRAYS FOR NONLINEAR OPTICAL VOLTAGE SENSING

      
Application Number US2024025411
Publication Number 2025/080301
Status In Force
Filing Date 2024-04-19
Publication Date 2025-04-17
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Zhao, Yuming
  • Xiao, Chuan
  • Zhou, Wei

Abstract

Embodiments of a novel nanolaminate nano-optoelectrode device and method for fabricating the same are described. In one example, a nano-optoelectrode device includes a conductive substrate and a nano-optoelectrode coupled to the conductive substrate. The nano-optoelectrode includes a metal-insulator-metal nanostructure coupled to the conductive substrate. The nano-optoelectrode further includes a conductive layer coupled to the conductive substrate and to a portion of the metal-insulator-metal nanostructure. The nano-optoelectrode further includes a nanocavity plasmonic hotspot formed on an exposed portion of the metal-insulator-metal nanostructure.

IPC Classes  ?

  • G01R 15/24 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using light-modulating devices
  • B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals

12.

FLEXIBLE MICROPOROUS MULTI-RESONANT PLASMONICS MESHES

      
Application Number 18726271
Status Pending
Filing Date 2022-11-04
First Publication Date 2025-04-10
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Garg, Aditya
  • Zhou, Wei
  • Vikesland, Peter J.

Abstract

Flexible multi-resonant plasmonic sheets, flexible microporous multi-resonant meshes, and dissolvable template-based hierarchical imprinting fabrication methods are described. A method of manufacture of a flexible microporous multi-resonant plasmonics mesh (MMPM) is described in one example. The method includes depositing alternating metal and insulating layers on a solvent-soluble nanowell array, to form a nanolaminate plasmonic crystal (NLPC) array on the solvent-soluble nanowell array. The method also includes pressing a hydrophobic curable resist over the NLPC array and the solvent-soluble nanowell array, using a watersoluble micropillar array as a working stamp for the pressing, curing the hydrophobic curable resist into a flexible scaffold, and dissolving the water-soluble micropillar array in water. The dissolving exposes a first side of the flexible scaffold, with the solvent-soluble nanowell array supporting a second side of the flexible scaffold. The method also includes dissolving the solvent-soluble nanowell array in a solvent, and separating the solvent-soluble nanowell array from the NLPC array and the flexible scaffold.

IPC Classes  ?

  • G02B 5/00 - Optical elements other than lenses
  • B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
  • B82Y 40/00 - Manufacture or treatment of nanostructures
  • G03F 7/00 - Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printed surfacesMaterials therefor, e.g. comprising photoresistsApparatus specially adapted therefor
  • G03F 7/038 - Macromolecular compounds which are rendered insoluble or differentially wettable
  • G03F 7/36 - Imagewise removal not covered by groups , e.g. using gas streams, using plasma

13.

3D-PRINTED INSTRUMENT FOR EQUINE CHONDROID REMOVAL

      
Application Number 18909045
Status Pending
Filing Date 2024-10-08
First Publication Date 2025-04-10
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Bogers, Sophie H.
  • Cardona, Guillermo C.

Abstract

Disclosed are various embodiments providing devices for lavage of a deeply recessed area and methods for using the same, such as in equine chondroid removal. The device can include a hollow insertion portion having a straight portion and a flexible curved distal end with a fluid egress aperture on a convex side of the curve and a rigid tubular handle connected to the straight portion of the hollow insertion portion.

IPC Classes  ?

  • A61D 1/00 - Surgical instruments for veterinary use

14.

DEMAND-ADAPTIVE MEMORY COMPRESSION IN HARDWARE

      
Application Number 18901218
Status Pending
Filing Date 2024-09-30
First Publication Date 2025-04-03
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor Jian, Xun

Abstract

Various aspects of a computing system for dynamically managing storage of data in a memory are described. In one example, a computing system includes a memory having a plurality of memory levels and a processing circuit configured to dynamically manage storage of data in the memory based on instructions received from an operating system (OS). To dynamically manage storage of the data, the processing circuit is further configured to determine a first memory level and a second memory level, where the first memory level is used to store uncompressed pages and the second memory level is used to store compressed pages. The processing circuit is further configured to determine a free list of free pages in the first memory level or the second memory level and store a page associated with the data in the first level or the second level based at least in part on the free list.

IPC Classes  ?

15.

BIODEGRADABLE POLYSACCHARIDE FILMS FOR PACKAGING

      
Application Number US2024047986
Publication Number 2025/072089
Status In Force
Filing Date 2024-09-23
Publication Date 2025-04-03
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Whittington, Abby R.
  • Gmati, Selma

Abstract

Biodegradable polysaccharide films for packaging are disclosed. One general aspect includes a biodegradable polysaccharide film exhibiting properties comparable to polyethylene and is biodegradable. The biodegradable polysaccharide film includes a blend of pullulan and chitosan. The biodegradable polysaccharide film also includes a crosslinking agent selected from glutaraldehyde or sodium tripolyphosphate. Another general aspect includes a method of making the biodegradable polysaccharide film.

IPC Classes  ?

  • B65D 65/38 - Packaging materials of special type or form
  • B65D 65/46 - Applications of disintegrable, dissolvable or edible materials

16.

AMPHIPHILIC POLYSACCHARIDES, POLYSACCHARIDE-BASED HYDROGELS, AND METHODS OF MANUFACTURE

      
Application Number 18974476
Status Pending
Filing Date 2024-12-09
First Publication Date 2025-03-27
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Edgar, Kevin J.
  • Nichols, Brittany L.B.
  • Chen, Junyi
  • Frazier, Charles
  • Norris, Ann

Abstract

A method for the synthesis of alkyl ω-carboxy(hydroxyethyl) polysaccharides is described. The method includes methylating or ethylating a polysaccharide or providing a methylated or ethylated polysaccharide, hydroxyethylating the methylated or ethylated polysaccharide, and oxidizing the hydroxyethylated polysaccharide to form the ω-carboxy(hydroxyethyl) polysaccharide. A method for the synthesis of oxidized polysaccharides is also described. The method includes hydroxypropylating a polysaccharide and oxidizing the hydroxypropylated polysaccharides. A method for the production of a solid capable of forming a hydrogel is also described. The method includes combining a first solution comprising an oxidized oligo(hydroxypropyl) polysaccharide bearing one or more ketone groups with a second solution comprising an amine substituted polysaccharide to form a third solution, and removing solvent from the third solution to form the solid, or adding an additional solvent to the third solution to precipitate the solid. Novel polysaccharides and hydrogels prepared according to these methods are also described.

IPC Classes  ?

  • C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
  • C08B 11/04 - Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
  • C08B 11/20 - Post-etherification treatments, including purification
  • C08B 31/12 - Ethers having alkyl or cycloalkyl radicals substituted by hetero atoms
  • C08B 31/18 - Oxidised starch
  • C08B 33/04 - Ethers
  • C08B 37/02 - DextranDerivatives thereof
  • C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules

17.

MATRIX INTEGRATED TRANSFORMER WITH BUILT-IN LEAKAGE INDUCTANCE

      
Application Number 18462723
Status Pending
Filing Date 2023-09-07
First Publication Date 2025-03-13
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Jin, Feng
  • Nabih, Ahmed
  • Li, Qiang

Abstract

Power converters with integrated transformers and resonant inductors are described. An example integrated transformer can be electrically coupled between a primary-side converter stage and a secondary-side converter stage in a power converter. The integrated transformer can include a magnetic core with plurality of core legs, a primary winding extending around each of the plurality of core legs, and a secondary winding extending around each of the plurality of core legs. A winding direction of the primary winding is alternated between adjacent core legs among the plurality of core legs, and a winding direction of the secondary winding is alternated between adjacent core legs among the plurality of core legs. Additionally, a number of winding turns of the primary winding and a number of winding turns of the secondary winding on a first core leg is different than on a second core leg among the plurality of core legs.

IPC Classes  ?

  • H01F 27/30 - Fastening or clamping coils, windings, or parts thereof togetherFastening or mounting coils or windings on core, casing, or other support
  • H01F 27/24 - Magnetic cores
  • H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only

18.

METHODS OF BIALLELIC MODIFICATION

      
Application Number 18885348
Status Pending
Filing Date 2024-09-13
First Publication Date 2025-03-13
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor Biase, Fernando

Abstract

Described herein are methods and techniques for biallelic modification of DNA.

IPC Classes  ?

  • C12N 15/90 - Stable introduction of foreign DNA into chromosome
  • C12N 9/22 - Ribonucleases
  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof

19.

SENSOR FOR ION DETECTION, METHODS OF CONSTRUCTION, AND USES THEREOF

      
Application Number US2024044235
Publication Number 2025/049612
Status In Force
Filing Date 2024-08-28
Publication Date 2025-03-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Ali, Azahar
  • Kachouei, Matin Ataei

Abstract

Various examples are provided related to a sensor (e.g., biosensor) for selective ion-detection in a sample. In one example, a potentiometric sensor includes a base; a working electrode (WE) set into the base; and a reference electrode (RE) set into the base adjacent to the working electrode. The working electrode includes a WE well filled with a WE solid-state material and the reference electrode includes a RE well, adjacent to the WE well, filled with a RE solid-state material. An example of a method for measuring a concentration of ions in a sample using the potentiometric sensor includes obtaining a biological sample; bringing the biological sample into contact with both the WE well and the RE well; and measuring the open circuit potential between the working electrode and the reference electrode. Also disclosed is a system comprising the disclosed sensor and a microfluidic device in fluid communication with the sensor.

IPC Classes  ?

20.

HYBRID DEVICE AND NETWORK ENTITY FOR A WIRELESS SYSTEM

      
Application Number US2024044393
Publication Number 2025/049721
Status In Force
Filing Date 2024-08-29
Publication Date 2025-03-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Tripathi, Nishithkumar
  • Reed, Jeffrey H.
  • Chintalapati, Rahul Varma

Abstract

The present disclosure is directed to a Hybrid Device and Network (HDN) entity for a wireless system. One general aspect includes an HDN entity that includes a processing unit configured to perform functions conventionally associated with a user equipment and to execute scheduling functions conventionally associated with a base station, where the scheduling functions may include allocating radio resources to one or more communication devices within a target coverage area of the HDN entity. The HDN entity also includes a control channel interface operably coupled to the processing unit. The control channel interface is configured to transmit and receive control signals used for managing the allocated radio resources for the one or more communication devices.

IPC Classes  ?

  • H04L 41/0803 - Configuration setting
  • H04L 41/0896 - Bandwidth or capacity management, i.e. automatically increasing or decreasing capacities
  • H04W 72/12 - Wireless traffic scheduling
  • H04L 67/50 - Network services
  • H04W 40/24 - Connectivity information management, e.g. connectivity discovery or connectivity update

21.

ASSEMBLY OF FLEXIBLE INTERCONNECTS USING SEDIMENTATION

      
Application Number US2024036387
Publication Number 2025/048947
Status In Force
Filing Date 2024-07-01
Publication Date 2025-03-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Bartlett, Michael D.
  • Ho, Dong Hae

Abstract

Embodiments of interplanar interconnects, intraplanar interconnects, and methods for forming the same in rigid, flexible, and stretchable substrates are described. In one example, a method for forming interplanar interconnects in a substrate includes injecting a solution into a mold cavity of a molding structure. The solution includes a polymer matrix and liquid metal elements. The method further includes performing a curing process on the solution to form an interplanar interconnect in the polymer matrix. The curing process includes exposing different regions of the solution to light while the molding structure is positioned in different orientations to cause selective sedimentation of the liquid metal elements in the solution.

IPC Classes  ?

  • H05K 1/03 - Use of materials for the substrate
  • H05K 1/09 - Use of materials for the metallic pattern

22.

CONDUCTIVE AND ADHESIVE LIQUID METAL COPPER PASTE

      
Application Number US2024044739
Publication Number 2025/049954
Status In Force
Filing Date 2024-08-30
Publication Date 2025-03-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Bartlett, Michael D.
  • Anand Tutika, Ravi Tej

Abstract

Embodiments of a liquid metal paste for coupling conductive components of circuits formed in or on rigid, flexible, and stretchable substrates are described. In one example, a liquid metal paste includes liquid metal. The liquid metal paste further includes copper elements mixed with the liquid metal to form a conductive mixture. In another example, the liquid metal paste further includes an elastomer material mixed with the liquid metal to form a conductive and adhesive mixture.

IPC Classes  ?

  • C09J 9/02 - Electrically-conducting adhesives
  • C09J 11/04 - Non-macromolecular additives inorganic
  • C09J 1/00 - Adhesives based on inorganic constituents

23.

SMART WORK ZONE SYSTEM

      
Application Number 18726259
Status Pending
Filing Date 2022-11-14
First Publication Date 2025-02-27
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Mollenhauer, Michael
  • Talledo Vilela, Jean Paul
  • White, Elizabeth
  • Cox, Christopher A
  • Roofigari-Esfahan, Nazila
  • Singhal, Sidhant

Abstract

Various embodiments of a system and method for a smart work zone are described. In one example, the system includes smart cone devices configured to transmit smart cone device localization data, a wearable device comprising a processor configured to transmit worker localization data of a worker wearing the garment device and to receive an alert, and a base station. The base station includes an internal edge computing system configured to process the smart cone device localization data to define a virtual geofence boundary of a safe area, process the worker localization data, broadcast a location of the worker wearing the wearable device, and in response to a vehicle or the worker approaching the virtual geofence boundary, provide an alert to at least one of: the worker wearing the wearable device, a passing motorist, or a connected and automated vehicle (CAV).

IPC Classes  ?

  • G08G 1/16 - Anti-collision systems
  • G08B 7/06 - Signalling systems according to more than one of groups Personal calling systems according to more than one of groups using electric transmission
  • G08B 21/02 - Alarms for ensuring the safety of persons
  • G08B 25/00 - Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems
  • G08B 25/01 - Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems characterised by the transmission medium
  • G08B 25/10 - Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems characterised by the transmission medium using wireless transmission systems
  • G08B 31/00 - Predictive alarm systems characterised by extrapolation or other computation using updated historic data
  • H04W 4/02 - Services making use of location information
  • H04W 4/021 - Services related to particular areas, e.g. point of interest [POI] services, venue services or geofences
  • H04W 4/44 - Services specially adapted for particular environments, situations or purposes for vehicles, e.g. vehicle-to-pedestrians [V2P] for communication between vehicles and infrastructures, e.g. vehicle-to-cloud [V2C] or vehicle-to-home [V2H]
  • H04W 4/90 - Services for handling of emergency or hazardous situations, e.g. earthquake and tsunami warning systems [ETWS]

24.

MULTI-DEVICE POWER CONSUMPTION OPTIMIZATION

      
Application Number 18726264
Status Pending
Filing Date 2023-01-06
First Publication Date 2025-02-20
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Kendurkar, Chinmay
  • Dongre, Poorvesh

Abstract

Disclosed are embodiments for a multi-device power consumption optimization framework that can conserve total power consumed across a collection of computing devices. In one embodiment, a method can include: obtaining power consumption characteristics data corresponding respectively to each of a plurality of computing devices associated with a user; generating a collective power saving strategy corresponding to the plurality of computing devices based on the power consumption characteristics data, the collective power saving strategy comprising one or more power saving operations that, when implemented, conserve a total amount of power used by the plurality of computing devices; and instructing one or more computing devices of the plurality of computing devices to perform at least one of the one or more power saving operations based on the user approval data.

IPC Classes  ?

  • G06F 1/3206 - Monitoring of events, devices or parameters that trigger a change in power modality
  • G06F 1/28 - Supervision thereof, e.g. detecting power-supply failure by out of limits supervision

25.

MULTIPHASE BUCK CONVERTERS WITH INTEGRATED COUPLED INDUCTORS AND CONTROLLABLE COUPLING

      
Application Number 18446888
Status Pending
Filing Date 2023-08-09
First Publication Date 2025-02-13
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Zhu, Feiyang
  • Li, Qiang
  • Lee, Fred C.

Abstract

Power converters with integrated controllable coupling inductors are described. An example power converter includes a number of converter stages and an integrated coupled inductor. The integrated coupled inductor includes a magnetic core having a first side leg, a first leg, a center leg, a second leg, and a second side leg. The integrated coupled inductor also includes a first and second windings for first and second converter stage among the converter stages. The first winding extends around the first leg, and the second winding extends around the second leg of the magnetic core. The integrated coupled inductor can also include a second magnetic core with third and fourth windings for additional converter stages and a coupling winding extending around center legs of the magnetic core and the second magnetic core. The integrated coupled inductor does not include a coupling inductor separate from the magnetic core and the second magnetic core.

IPC Classes  ?

  • H02M 1/00 - Details of apparatus for conversion
  • H01F 27/30 - Fastening or clamping coils, windings, or parts thereof togetherFastening or mounting coils or windings on core, casing, or other support
  • H01F 27/38 - Auxiliary core membersAuxiliary coils or windings
  • H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load

26.

Learning approximate estimation networks for communication channel state information

      
Application Number 18218855
Grant Number 12223443
Status In Force
Filing Date 2023-07-06
First Publication Date 2025-02-11
Grant Date 2025-02-11
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • O'Shea, Timothy James
  • Karra, Kiran
  • Clancy, T. Charles

Abstract

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training and deploying machine-learning estimation networks in a communications system. One of the methods includes: processing first information with ground truth information to generate a first RF signal by altering the first information by channel impairment having at least one channel effect, using a receiver to process the first RF signal to generate second information, training a machine-learning estimation network based on a network architecture, the second information, and the ground truth information, receiving by the receiver a second RF signal transmitted through a communication channel including the at least one channel effect, inferring by the trained estimation network the receiver to estimate an offset of the second RF signal caused by the at least one channel effect, and correcting the offset of the RF signal with the estimated offset to obtain a recovered RF signal.

IPC Classes  ?

27.

BROAD-WAVELENGTH OPTICAL RETARDATION THROUGH IN-PLANE OPTICAL ANISOTROPY OF SINGLE CRYSTALLINE MATERIALS

      
Application Number US2024039612
Publication Number 2025/029594
Status In Force
Filing Date 2024-07-25
Publication Date 2025-02-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Quan, Lina
  • Dou, Yixuan

Abstract

In one aspect, the disclosure relates to a variety of crystalline materials that have a 2D crystal structure and an in-plane anisotropy. The crystalline materials can include metals having a partially filled d shell and that undergo a Jahn-Teller distortion. The crystalline materials can include incorporating two organic spacers in the same repeating layers to induced additional out-of-plane heterogeneity. The crystalline materials can exhibit broad wavelength optical retardation. The materials can be used in lenses such as in an achromatic quarter waveplate (A-QWP).

IPC Classes  ?

28.

INTEGRATED TRANSFORMER-INDUCTOR AND EMI SHIELD

      
Application Number 18362222
Status Pending
Filing Date 2023-07-31
First Publication Date 2025-02-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Nabih, Ahmed
  • Jin, Feng
  • Li, Qiang

Abstract

Power converters with integrated transformers and resonant inductors are described. An example power converter includes a primary-side converter stage, a number of secondary-side converter stages, and an integrated transformer and resonant inductor coupled between the primary-side and secondary-side converter stages. The integrated transformer includes a magnetic core having a first leg, an auxiliary leg, and a second leg. The integrated transformer also includes a first transformer having a first primary winding, a first secondary winding, and a first shield winding on the first leg, and a second transformer having a second primary winding, a second secondary winding, and a second shield winding on the second leg. The first shield winding is electrically coupled to provide an extension of the first primary winding for the first transformer, and an end of the first shield winding or the second shield winding is electrically coupled to a primary-side ground of the power converter.

IPC Classes  ?

  • H01F 27/28 - CoilsWindingsConductive connections
  • H01F 27/26 - Fastening parts of the core togetherFastening or mounting the core on casing or support
  • H02M 1/00 - Details of apparatus for conversion
  • H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only

29.

TRAPEZOIDAL CURRENT CONTROL IN ELECTRONIC TRANSFORMERS

      
Application Number 18364088
Status Pending
Filing Date 2023-08-02
First Publication Date 2025-02-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Cao, Yuliang
  • Dong, Dong

Abstract

Power converters including electronic-embedded transformers for current sharing and load-independent voltage gain are described. An example power converter system includes an input, an output, a power converter between the input and output, and a controller. The converter includes a first bridge, a second bridge, and an electronic-embedded transformer (EET) between the first and second bridge. The EET includes a capacitor and a capacitance coupling switch bridge. The controller generates phasing drive control signals for trapezoidal current modulation control of the capacitance coupling switch bridge of the EET. The controller is configured to generate the phasing drive control signals based on a phase shift coefficient, k, to set a duty cycle of a voltage from the capacitance coupling switch bridge. The controller is also configured to vary k from between 0 to 0.5 based on a load applied to the power converter system or other operating aspects of the power converter.

IPC Classes  ?

  • H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
  • H02M 1/00 - Details of apparatus for conversion

30.

RESONANT COMMUTATION AND QUASI-TRAPEZOIDAL CURRENT CONTROL IN ELECTRONIC TRANSFORMERS

      
Application Number 18364113
Status Pending
Filing Date 2023-08-02
First Publication Date 2025-02-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Cao, Yuliang
  • Dong, Dong

Abstract

Power converters including electronic-embedded transformers for current sharing and load-independent voltage gain are described. An example power converter system includes an input, an output, a power converter between the input and output, and a controller. The converter includes a first bridge, a second bridge, and an electronic-embedded transformer between the first and second bridge. The electronic-embedded transformer includes a bidirectional coupling switch bridge. The controller generates drive control signals for quasi-trapezoidal current modulation control of the bidirectional coupling switch bridge. The controller is configured to generate the drive control signals based on a commutation coefficient k and a switching frequency for the power converter. The commutation coefficient k can be set based on an inductance in the electronic-embedded transformer, a capacitance in the bidirectional coupling switch bridge, and a margin for resonant current commutation.

IPC Classes  ?

  • H02M 1/08 - Circuits specially adapted for the generation of control voltages for semiconductor devices incorporated in static converters
  • H02M 3/00 - Conversion of DC power input into DC power output
  • H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only

31.

HYDROLYZED PROTEIN SERUM REPLACEMENT COMPOSITIONS

      
Application Number 18709370
Status Pending
Filing Date 2022-11-10
First Publication Date 2025-02-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Ovissipour, Reza
  • Duscher, Alexandrea
  • Batish, Inayat
  • Zarei, Mohammad

Abstract

Described in several exemplary embodiments herein are serum replacement compositions, cell culture media containing said serum replacement compositions, and uses thereof.

IPC Classes  ?

  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
  • C07K 14/39 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from fungi from yeasts
  • C07K 14/405 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from algae
  • C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C12N 9/54 - Proteinases derived from bacteria bacteria being Bacillus

32.

LEARNING RADIO SIGNALS USING RADIO SIGNAL TRANSFORMERS

      
Application Number 18799049
Status Pending
Filing Date 2024-08-09
First Publication Date 2025-02-06
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor O`shea, Timothy James

Abstract

Methods, systems, and apparatus, including computer programs encoded on a storage medium, for processing radio signals. In once aspect, a system is disclosed that includes a processor and a storage device storing computer code that includes operations. The operations may include obtaining first output data generated by a first neural network based on the first neural network processing a received radio signal, receiving, by a signal transformer, a second set of input data that includes (i) the received radio signal and (ii) the first output data, generating, by the signal transformer, data representing a transformed radio signal by applying one or more transforms to the received radio signal, providing the data representing the transformed radio signal to a second neural network, obtaining second output data generated by the second neural network, and determining based on the second output data a set of information describing the received radio signal.

IPC Classes  ?

  • G06N 3/08 - Learning methods
  • G06N 3/045 - Combinations of networks
  • H04B 1/00 - Details of transmission systems, not covered by a single one of groups Details of transmission systems not characterised by the medium used for transmission
  • H04B 17/309 - Measuring or estimating channel quality parameters

33.

DEEP LEARNING FOR SOUND SPEED IMAGING USING PULSE-ECHO ULTRASOUND

      
Application Number US2024038975
Publication Number 2025/024362
Status In Force
Filing Date 2024-07-22
Publication Date 2025-01-30
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor Han, Aiguo

Abstract

Provided are methods of creating a trained deep neural network, in embodiments the methods comprising: providing a number of natural images; converting each natural image into a speed of sound (SoS) map; for each of the SoS maps, deriving a theoretical time-shift map; and training a deep neural network based on time-shift and SoS map pairs, each of the pairs comprising one of the theoretical time-shift maps and its corresponding SoS map; wherein the deep neural network is capable of reconstructing a speed of sound (SoS) image from a measured time-shift map generated from ultrasound.

IPC Classes  ?

34.

SLED-BASED TRIBOMETER AND PROCESS FOR MEASURING FRICTION COEFFICIENTS

      
Application Number US2024039296
Publication Number 2025/024524
Status In Force
Filing Date 2024-07-24
Publication Date 2025-01-30
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Rowson, Steve
  • Stark, Nicole

Abstract

Embodiments of a device and methodology for measuring friction coefficients of different irregularly shaped objects against different materials are described. One example device includes a sub-frame slidably coupled to a frame. The device further includes an object mount coupled to the sub-frame, a sliding surface under the object mount, and an instrumented sled on the sliding surface. The instrumented sled includes a support platform to support a material sample under the object mount. The device further includes a tension loadcell coupled to the instrumented sled and a tension load application coupled to the tension loadcell. The instrumented sled is configured to measure a normal force applied to the material sample by an irregularly shaped object coupled to the object mount during operation of the device. The tension load application is operable to apply a tangential force to the instrumented sled. The tension loadcell is operable to measure the tangential force.

IPC Classes  ?

  • G01N 19/02 - Measuring coefficient of friction between materials
  • G01N 3/24 - Investigating strength properties of solid materials by application of mechanical stress by applying steady shearing forces
  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups

35.

SCATTERING ARRAY INTERFEROMETERS

      
Application Number US2024039602
Publication Number 2025/024695
Status In Force
Filing Date 2024-07-25
Publication Date 2025-01-30
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Shi, Guannan
  • Wang, Anbo
  • Zhu, Yizheng

Abstract

Disclosed are various embodiments for scattering array interferometers. In one embodiment, an optical medium comprises one or more scattering array interferometers in the optical medium. Each of the scattering array interferometers includes a respective array or other spatial distribution of scatterers/reflectors comprising at least two scatterers/reflectors that are uniformly sized and spaced according to a corresponding pitch. The respective array or other spatial distribution of scatterers/reflectors is configured to cause coherent light interference when a light source is applied to the optical medium.

IPC Classes  ?

  • G01M 11/02 - Testing optical properties
  • G01B 9/02017 - Interferometers characterised by the beam path configuration with multiple interactions between the target object and light beams, e.g. beam reflections occurring from different locations
  • G01L 1/24 - Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis
  • G01B 11/16 - Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge
  • G01N 21/45 - RefractivityPhase-affecting properties, e.g. optical path length using interferometric methodsRefractivityPhase-affecting properties, e.g. optical path length using Schlieren methods
  • G01N 21/47 - Scattering, i.e. diffuse reflection

36.

METHODS FOR PREVENTING OR REDUCING BACTERIAL INFECTION OF PLANT SEEDS

      
Application Number 18894249
Status Pending
Filing Date 2024-09-24
First Publication Date 2025-01-16
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Welbaum, Gregory E.
  • Zhao, Bingyu
  • Kiremit, Merve

Abstract

Described herein are methods preventing or reducing a bacterial infection on a plant seed. In one aspect, the method involves applying to the plant seed epigallocatechin-3 gallate, catechin, epicatechin, or any combination thereof. In one aspect, a mixture comprising epigallocatechin-3 gallate, catechin, and epicatechin is applied to the plant seed. In another aspect, green tea is applied to the plant seed. In other aspects, epigallocatechin-3 gallate, catechin, epicatechin, or any combination thereof is applied to plant seed in combination with an antibiotic, where a synergistic effect is observed. In other aspects, epigallocatechin-3 gallate, catechin, epicatechin, or any combination thereof is added to soil before and/or after the seed is planted in the soil.

IPC Classes  ?

  • A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
  • A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
  • A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
  • A01N 65/08 - Magnoliopsida [dicotyledons]
  • A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

37.

GENERATING ELECTROMAGNETIC WAVES FOR TRANSCRANIAL MAGNETIC STIMULATION

      
Application Number 18708683
Status Pending
Filing Date 2022-11-18
First Publication Date 2025-01-09
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Hosseini-Fahraji, Ali
  • Manteghi, Majid

Abstract

Aspects of transcranial magnetic stimulation (TMS) devices are described. In one example, the TMS device includes a magnetic flux shutter that includes a multi-turn coil and a magnetic film. The magnetic film extends in a loop to encircle a region, and the multi-turn coil is continuously wound around the magnetic film. The TMS device also includes a magnet that is positioned in the region within a boundary of the magnetic film, with the magnet generating a magnetic flux. The TMS device also includes a current source coupled to the multi-turn coil. The current source is configured to deliver a current to the multi-turn coil, to vary a permeability of the magnetic film and a density of the magnetic flux extending outside the region of the magnetic flux shutter during operation.

IPC Classes  ?

  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61N 2/00 - Magnetotherapy
  • A61N 2/06 - Magnetotherapy using magnetic fields produced by permanent magnets

38.

VIRTUAL REALITY CLINICAL IMMERSION

      
Application Number 18763083
Status Pending
Filing Date 2024-07-03
First Publication Date 2025-01-09
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Wayne, Jennifer S.
  • Moore, Cameron
  • Santos Lages, Wallace

Abstract

Disclosed herein are methods and systems for creating educational virtual reality environments. One or more cameras may capture 360-degree images of a medical environment. Each of the 360-degree images are captured with a camera being placed at a respective location. A computing device may create a virtual reality environment of the medical environment based on the 360-degree images, by, for each of the 360-degree images, placing a user viewpoint at the respective location of the respective camera that captured the respective 360-degree image, placing a graphical representation of a first class at each other respective location that is visible in the respective 360-degree image, and placing a graphical representation of a second class over each object visible in the respective 360-degree image that has particular educational content assigned to the object. The computing device may output, for interactive display at a virtual reality device, the virtual reality environment.

IPC Classes  ?

  • G06T 19/00 - Manipulating 3D models or images for computer graphics
  • G09B 5/06 - Electrically-operated educational appliances with both visual and audible presentation of the material to be studied

39.

MODULAR CAVITATION GENERATOR AND INTENSITY ADJUSTING METHODS

      
Application Number 18708681
Status Pending
Filing Date 2022-11-22
First Publication Date 2025-01-02
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Ge, Mingming
  • Coutier-Delgosha, Olivier

Abstract

A modular assembled cavitation generating device and related operating loop are described adapted for intensity adjustment, observation, and temperature control. The device is adapted to receive one or more modules detachably attachable to the device that define surface materials, dimensions, angles, and other parameters of a cavitation channel, such as a venturi cavitation channel, that controls or otherwise adjusts cavitation occurring within the device. The device further includes observation windows for monitoring, and various measurement sensors can be installed to obtain measurements pertaining to various flow fields. Additional methods for controlling and/or intensifying cavitation through setting an optimum temperature range are also described.

IPC Classes  ?

  • B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
  • B01J 19/24 - Stationary reactors without moving elements inside
  • G01F 1/44 - Venturi tubes

40.

METHODS FOR EXTRACTING RARE EARTH ELEMENTS FROM ION-ADSORPTION CLAYS

      
Application Number 18815220
Status Pending
Filing Date 2024-08-26
First Publication Date 2024-12-19
Owner Virginia Tech Intellectual Properties Inc. (USA)
Inventor
  • Noble, Christopher Aaron
  • Yoon, Roe-Hoan

Abstract

Methods of extracting rare earth elements (REEs) from low-grade REE sources composed of clayey materials. In one aspect, the REE sources are the waste materials generated in the coal and kaolin clay industries during the courses of upgrading mined coal and kaolinite. The methods described herein include the steps of pre-concentrating REE-bearing minerals using physical separation methods to prepare high-grade feedstocks for the chemical extraction of high-value REEs and critical materials while minimizing both the capital and operating costs.

IPC Classes  ?

  • C22B 59/00 - Obtaining rare earth metals
  • C22B 1/11 - Removing sulfur, phosphorus or arsenic, other than by roasting
  • C22B 3/14 - Extraction of metal compounds from ores or concentrates by wet processes by leaching in inorganic alkaline solutions containing ammonia or ammonium salts
  • C22B 3/18 - Extraction of metal compounds from ores or concentrates by wet processes with the aid of microorganisms or enzymes, e.g. bacteria or algae

41.

ENGINEERED PHAGES AND USES THEREOF

      
Application Number US2024033677
Publication Number 2024/259013
Status In Force
Filing Date 2024-06-12
Publication Date 2024-12-19
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Hsu, Bryan
  • Baker, Zachary
  • Li, Liwu

Abstract

Described in certain example embodiments herein are engineered phages comprising one or more heterologous genes that encode one or more heterologous gene products and methods of using the engineered phages to deliver one or more heterologous gene products to a subject.

IPC Classes  ?

  • A61K 35/76 - VirusesSubviral particlesBacteriophages
  • A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof

42.

ANTI-PATHOGEN PHAGES PRODUCED FROM MICROBES AND METHODS OF USE

      
Application Number US2024033903
Publication Number 2024/259165
Status In Force
Filing Date 2024-06-13
Publication Date 2024-12-19
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Hsu, Bryan
  • Bataglioli, Rogerio
  • Baaziz, Hiba

Abstract

The present disclosure provides genetically modified microbes. A genetically modified microbe includes a lysogenic P22 phage and at least one exogenous coding region. The exogenous coding region can encode a Salmonella modification system methylase, a C2 protein, a C2-inhibiting protein, rfb gene cluster coding regions and a rfc coding region, or a combination thereof. Also provided are compositions that include the genetically modified microbe and methods of using the genetically modified microbe.

IPC Classes  ?

  • A61K 35/76 - VirusesSubviral particlesBacteriophages
  • A61P 31/04 - Antibacterial agents
  • C12N 15/90 - Stable introduction of foreign DNA into chromosome

43.

METAMATERIAL ADHESIVES FOR PACKAGING, HANGING, HANDLING, AND SHEAR LOADING

      
Application Number US2024032826
Publication Number 2024/254321
Status In Force
Filing Date 2024-06-06
Publication Date 2024-12-12
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Bartlett, Michael D.
  • Lee, Chanhong
  • Hwang, Dohgyu

Abstract

Metamaterial adhesives and metamaterial adhesive systems are described. The metamaterial adhesive systems simultaneously achieve strong and releasable adhesion with spatially selectable adhesion strength through programmed cut architectures. The programmed cut architectures define flap and interconnect regions on a metamaterial adhesive film or a substrate having the metamaterial adhesive film deposited on at least one side of the substrate, among other examples. An example metamaterial adhesive system includes a flexible strip having multiple flaps formed on the flexible strip and a metamaterial adhesive or film deposited on at least one side of one or more of the multiple flaps.

IPC Classes  ?

  • B32B 3/26 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids
  • B32B 7/06 - Interconnection of layers permitting easy separation
  • B32B 25/08 - Layered products essentially comprising natural or synthetic rubber comprising rubber as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin
  • B32B 25/20 - Layered products essentially comprising natural or synthetic rubber comprising silicone rubber

44.

HUMAN POWERED SOFT ROBOTICS FOR NEUROMUSCULAR DISORDERS

      
Application Number US2024032962
Publication Number 2024/254420
Status In Force
Filing Date 2024-06-07
Publication Date 2024-12-12
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Arena, Christopher
  • Trader, William

Abstract

An apparatus may include at least one sensor bladder for positioning in relation to the foot of a user. An apparatus may also include at least one stimulation bladder corresponding to the respective at least one sensor bladder, the at least one stimulation bladder positioned on the body of the user remotely from the foot. An apparatus may include at least one conduit fluidly coupling the respective at least one sensor bladder with the respective at least one stimulation bladder, where the at least one sensor bladder is configured to compress responsive to movement of the foot of the user and drive fluid from the at least one sensor bladder to the respective at least one stimulation bladder via the respective at least one conduit.

45.

CASCADE DEGRADATION AND UPCYCLING OF POLYSTYRENE WASTE TO HIGH VALUE CHEMICALS

      
Application Number 18695210
Status Pending
Filing Date 2022-09-24
First Publication Date 2024-11-28
Owner
  • Virginia Tech Intellectual Properties, Inc. (USA)
  • INSTAGRID GMBH (Germany)
Inventor
  • Liu, Guoliang
  • Xu, Zhen

Abstract

A method of converting polystyrene to diphenylmethane using either UV light and or heat and a Lewis acid is disclosed.

IPC Classes  ?

  • C08J 11/20 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with hydrocarbons or halogenated hydrocarbons
  • C08J 3/205 - Compounding polymers with additives, e.g. colouring in the presence of a liquid phase

46.

DROPLET-BASED SINGLE-CELL EPIGENOMIC ASSAY

      
Application Number US2024030824
Publication Number 2024/243433
Status In Force
Filing Date 2024-05-23
Publication Date 2024-11-28
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Lu, Chang
  • Zhang, Qiang

Abstract

Methods and systems of single-cell bisulfite sequencing are provided. The single-cell bisulfite sequencing techniques of the disclosure involve single-cell DNA (scDNA) droplets, where the scDNA are fragmented within the scDNA droplets prior to bisulfite conversion. The methods and systems further include barcode droplets, and fusing the scDNA droplets with the barcode droplets to form barcoded scDNA droplets for bisulfite conversion. The bisulfite conversion beneficially occurs within the bisulfite droplets to reduce DNA degradation. The single-cell bisulfite sequencing method and systems provide for bisulfite sequenced nucleic acid libraries.

IPC Classes  ?

  • C12Q 1/6869 - Methods for sequencing
  • C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
  • C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
  • C12N 15/09 - Recombinant DNA-technology

47.

NANOPOROUS ALLOYS

      
Application Number 18628213
Status Pending
Filing Date 2024-04-05
First Publication Date 2024-11-21
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Hin, Celine
  • Worden, Jarod
  • Corcoran, Sean

Abstract

The disclosure relates to nanoporous alloys, and methods to prepare them.

IPC Classes  ?

  • C22C 1/08 - Alloys with open or closed pores

48.

LOWER BODY EXOSKELETON WITH A LINEAR ACTUATOR

      
Application Number 18669021
Status Pending
Filing Date 2024-05-20
First Publication Date 2024-11-21
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor Asbeck, Alan

Abstract

Embodiments of lower body exoskeletons having linear actuators are described. In one example, an exoskeleton includes an upper juncture assembly for positioning at least partly around a waist of a user. The exoskeleton further includes a linear actuator having a first end and a second end opposite the first end. The first end of the linear actuator is coupled to the upper juncture assembly. The exoskeleton further includes a lower juncture assembly coupled to the second end of the linear actuator. The lower juncture assembly is configured for positioning the second end of the linear actuator at a side of a foot of the user. The exoskeleton further includes a foot attachment interface for positioning at least partly around the foot of the user.

IPC Classes  ?

  • A61H 3/00 - Appliances for aiding patients or disabled persons to walk about
  • A61H 1/02 - Stretching or bending apparatus for exercising
  • B25J 9/00 - Programme-controlled manipulators

49.

ELECTRODE RECYCLING VIA RAPID, HIGH-TEMPERATURE HEATING

      
Application Number 18660510
Status Pending
Filing Date 2024-05-10
First Publication Date 2024-11-14
Owner
  • UNIVERSITY OF MARYLAND, COLLEGE PARK (USA)
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Hu, Liangbing
  • Wang, Xizheng
  • Li, Tangyuan
  • Lin, Feng
  • Tao, Lei

Abstract

Degraded electrode material from a used battery can be recycled by subjecting to a thermal shock. The degraded electrode material can have impurities resulting from charge/discharge cycling of the battery. The thermal shock can have a temperature of at least 1000 K for a time period of 10 seconds or less, for example, less than or equal to 1 second. The thermal shock can also include a heating rate of at least 103 K/second preceding the time period and a cooling rate of at least 103 K/second following the time period. The subjecting to the thermal shock regenerate the electrode material, for example, by removing impurities from the electrode material and/or replenishing metal ions within the electrode material.

IPC Classes  ?

  • H01M 4/04 - Processes of manufacture in general
  • B09B 3/40 - Destroying solid waste or transforming solid waste into something useful or harmless involving thermal treatment, e.g. evaporation
  • B09B 101/16 - Batteries

50.

OPTOELECTRODE ARRAYS BY HIERARCHICAL MODULAR DESIGN

      
Application Number US2023076254
Publication Number 2024/232929
Status In Force
Filing Date 2023-10-06
Publication Date 2024-11-14
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Mejia, Elieser
  • Zhou, Wei

Abstract

Concepts directed to multi-modal bio-interfacing devices and methods for fabricating and implementing the same are described. In one example, a device for bio-interfacing applications includes a multi-modal bio-interfacing structure formed on a substrate. The multi-modal bio-interfacing structure includes a microelectrode pad formed on the substrate and a micropillar electrode extending from the microelectrode pad. The multi-modal bio-interfacing structure further includes a plurality of nanoantennas formed on the micropillar electrode.

IPC Classes  ?

  • B82Y 40/00 - Manufacture or treatment of nanostructures
  • A61B 5/25 - Bioelectric electrodes therefor
  • B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

51.

B. BURGDORFERI PEPTIDOGLYCAN ANTIBODIES AND USES THEREOF

      
Application Number US2024028602
Publication Number 2024/233792
Status In Force
Filing Date 2024-05-09
Publication Date 2024-11-14
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor Jutras, Brandon

Abstract

Described herein are compositions, assays, techniques, methods, for treating and/or detecting a Borrelia burgdorferi microorganism, the causative agent of Lyme disease.

IPC Classes  ?

  • A61K 39/40 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum bacterial
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C07K 14/20 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

52.

EXTRACELLULAR VESICLE COMPOSITIONS AND PREPARATION

      
Application Number US2024028635
Publication Number 2024/233809
Status In Force
Filing Date 2024-05-09
Publication Date 2024-11-14
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Marsh, Spencer
  • Gourdie, Robert G.
  • Jourdan, Linda Jane
  • Dogan, Alan

Abstract

In various aspects and embodiments provided are compositions containing extracellular vesicles (including modified extracellular vesicles), methods of making preparations of extracellular vesicles, methods of modifying extracellular vesicles and methods of using modified and/or unmodified extracellular vesicles.

IPC Classes  ?

  • A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
  • C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
  • C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
  • B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
  • A61K 9/51 - Nanocapsules

53.

TAPERED DRUG DELIVERY, OPTICAL STIMULATION, AND ELECTROPHYSIOLOGY PROBE FOR NEURAL INTERFACING

      
Application Number US2024027708
Publication Number 2024/229372
Status In Force
Filing Date 2024-05-03
Publication Date 2024-11-07
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Jia, Xiaoting
  • English, Daniel Fine
  • Huang, Hengji
  • Kim, Jongwoon
  • Gilbert, Earl Thomas

Abstract

Multi-modal fiber probe devices and processes for fabricating the same are described. In one example, a multi-modal fiber probe device can include a flexible tapered fiber probe structure having a micro-scale tip region at a first end and a macro-scale connector region at a second end opposite the first end. The multi-modal fiber probe device can further include an optical waveguide positioned in and extending through the flexible tapered fiber probe structure from the micro-scale tip region to the macro-scale connector region. The multi-modal fiber probe device can further include a microfluidic channel formed in and extending through the flexible tapered fiber probe structure from the micro-scale tip region to the macro-scale connector region.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • G01D 5/32 - Mechanical means for transferring the output of a sensing memberMeans for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for convertingTransducers not specially adapted for a specific variable using optical means, i.e. using infrared, visible or ultraviolet light with attenuation or whole or partial obturation of beams of light
  • G01P 3/36 - Devices characterised by the use of optical means, e.g. using infrared, visible, or ultraviolet light
  • A61B 5/293 - Invasive
  • H01H 85/157 - Ferrule-end contacts

54.

METHODS FOR EXTRACTING RARE EARTH ELEMENTS FROM RARE EARTH ELEMENT SOURCES

      
Application Number 18255665
Status Pending
Filing Date 2021-12-04
First Publication Date 2024-11-07
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Yoon, Roe-Hoan
  • Noble, Christopher Aaron
  • Council-Troche, Roberto Mcalister
  • Liu, Wei

Abstract

Described herein are methods for methods for extracting earth elements from rare earth element sources. In one aspect, the rare earth element source includes clayey materials present in coal and coal by-products, where one or more rare earth elements are adsorbed on the clayey materials. The methods involve admixing the rare earth element source with a base and an electrolyte composition. In one aspect, the electrolyte composition includes a chelating agent and/or a complexing agent. The extraction process is conducted at temperatures less than or equal to 100° C., which makes the process cost-effective and sustainable.

IPC Classes  ?

  • C22B 59/00 - Obtaining rare earth metals
  • C22B 1/14 - AgglomeratingBriquettingBindingGranulating
  • C22B 3/12 - Extraction of metal compounds from ores or concentrates by wet processes by leaching in inorganic alkaline solutions
  • C22B 3/22 - Treatment or purification of solutions, e.g. obtained by leaching by physical processes, e.g. by filtration, by magnetic means
  • C22B 3/42 - Treatment or purification of solutions, e.g. obtained by leaching by ion-exchange extraction

55.

INCREASING FLOTATION RECOVERY AND THROUGHPUT

      
Application Number 18692153
Status Pending
Filing Date 2022-09-16
First Publication Date 2024-11-07
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Yoon, Roe-Hoan
  • Huang, Kaiwu
  • Gupta, Mohit
  • Noble, Christopher Aaron

Abstract

Various examples are provided in relation to improved recovery and throughput of both fine and coarse particulate materials. In one example, a method includes injecting an aqueous suspension of a cloud of small air bubbles into an aqueous phase including fine particulate materials, wherein the fine particulate material is selectively hydrophobized and collected by small air bubbles; allowing the bubbles to rise in the aqueous phase; and collecting the air bubbles to obtain a concentrate of the fine particulate materials. In another example, a method includes adding a hydrophobizing agent to an aqueous phase to render coarse particulate material selectively hydrophobic; allowing air bubbles to attach to the coarse particulate material and changing the apparent specific gravity of the coarse particulate materials so a layer of one type of coarse particle is formed on top; allowing the one type of coarse particles to float and enter the forth phase.

IPC Classes  ?

  • B03D 1/02 - Froth-flotation processes
  • B03D 1/14 - Flotation machines
  • B03D 1/24 - Flotation machines pneumatic
  • C02F 1/24 - Treatment of water, waste water, or sewage by flotation
  • C02F 101/20 - Heavy metals or heavy metal compounds
  • C22B 3/22 - Treatment or purification of solutions, e.g. obtained by leaching by physical processes, e.g. by filtration, by magnetic means
  • C22B 15/00 - Obtaining copper

56.

UPCYCLING OF POLYETHYLENE AND POLYPROPYLENE AND THEIR MIXTURES TO HIGH-VALUE SURFACTANTS

      
Application Number US2024026720
Publication Number 2024/227121
Status In Force
Filing Date 2024-04-28
Publication Date 2024-10-31
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Liu, Guoliang
  • Xu, Zhen
  • Munyaneza, Nuwayo

Abstract

Herein, a method for controlling the thermolysis products molar mass using a coolant fluid (e.g., water) to modulate the final products' condensation temperatures. With this strategy, the thermolysis of polyethylene (PE) and polypropylene (PP) is tailored to generate liquid oil, without any catalysts or additives. Subsequent addition of sulfuric acid across the alkenyl groups, followed by the neutralization with sodium hydroxide affords sulfate detergents with excellent foaming behavior.

IPC Classes  ?

  • C11C 3/00 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis
  • C07C 4/02 - Preparation of hydrocarbons from hydrocarbons containing a larger number of carbon atoms by cracking a single hydrocarbon or a mixture of individually defined hydrocarbons or a normally gaseous hydrocarbon fraction
  • C08L 91/06 - Waxes
  • C10G 1/10 - Production of liquid hydrocarbon mixtures from oil shale, oil-sand, or non-melting solid carbonaceous or similar materials, e.g. wood, coal from rubber or rubber waste

57.

SYSTEMS AND METHODS FOR PROTECTING BYSTANDER VISUAL DATA IN AUGMENTED REALITY SYSTEMS

      
Application Number US2024023077
Publication Number 2024/211572
Status In Force
Filing Date 2024-04-04
Publication Date 2024-10-10
Owner
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
  • PURDUE RESEARCH FOUNDATION (USA)
  • MONTCLAIR STATE UNIVERSITY (USA)
Inventor
  • Corbett, Matthew
  • David- John, Brendan Matthew
  • Shang, Jiacheng
  • Hu, Charlie
  • Ji, Bo

Abstract

Embodiments of the present disclosure introduce approaches for protecting bystander privacy in a wearable augmented reality (AR) device. In one embodiment, a video frame is captured via a camera of the wearable AR device, and faces are detected in the video frame. A first face is classified as a subject based at least in part on eye gaze tracking of a user of the wearable AR device by an eye gaze sensor of the wearable AR device. A second face is classified as a bystander based at least in part on the eye gaze tracking of the user. The second face is obscured in the video frame in response to the second face being classified as the bystander.

IPC Classes  ?

  • G06F 21/62 - Protecting access to data via a platform, e.g. using keys or access control rules
  • G06T 5/00 - Image enhancement or restoration
  • G06T 7/70 - Determining position or orientation of objects or cameras
  • G06V 10/22 - Image preprocessing by selection of a specific region containing or referencing a patternLocating or processing of specific regions to guide the detection or recognition
  • G06V 40/16 - Human faces, e.g. facial parts, sketches or expressions
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • G10L 25/51 - Speech or voice analysis techniques not restricted to a single one of groups specially adapted for particular use for comparison or discrimination
  • H04W 12/63 - Location-dependentProximity-dependent

58.

INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY

      
Application Number US2024021158
Publication Number 2024/206153
Status In Force
Filing Date 2024-03-22
Publication Date 2024-10-03
Owner
  • UNIVERSITY OF VIRGINIA PATENT FOUNDATION (USA)
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Lynch, Kevin R.
  • Kharel, Yugesh
  • Huang, Tao
  • Santos, Webster L.
  • Shrader, Christopher
  • Dunnavant, Kyle
  • Burgio, Ariel Louise
  • Bage, Andrew D.

Abstract

The present disclosure provides SPNS2 inhibitor compounds according to Formula I: where T, U, V, W, X, R1, R2, and m are defined herein. The present disclosure also provides pharmaceutically acceptable salts, and/or tautomers of Formula I compounds as described in the disclosure. Also provided are their methods of use in therapy, such as in diseases for which immunomodulation and/or anti-fibrotic activity is indicated.

IPC Classes  ?

  • C07D 213/65 - One oxygen atom attached in position 3 or 5
  • C07D 235/16 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
  • C07D 295/195 - Radicals derived from nitrogen analogues of carboxylic acids
  • C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
  • C07D 487/08 - Bridged systems
  • C07D 487/10 - Spiro-condensed systems
  • A61P 35/00 - Antineoplastic agents
  • A61P 11/06 - Antiasthmatics
  • A61P 37/00 - Drugs for immunological or allergic disorders
  • A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin

59.

NANOFIBER NETWORKS AS MEMBRANE MIMICS FOR IN VITRO APPLICATIONS

      
Application Number 18573665
Status Pending
Filing Date 2022-06-25
First Publication Date 2024-09-26
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Graybill, Philip
  • Davalos, Rafael
  • Jana, Aniket
  • Nain, Amrinder

Abstract

Various examples are provided related to nanofiber networks that can mimic in vivo physiology. In one example, a scaffold includes a nanofiber membrane extending across a scaffold opening. The nanofiber membrane can include a stack of nanofiber layers that include nanofibers disposed with a controlled orientation or direction and a controlled spacing. The nanofibers are cross-linked with nanofibers of an adjacent nanofiber layer. The scaffold can be incorporated into a transwell insert or plate. In another example, a microfluidic chip can include a first channel layer with a first fluid channel; a second channel layer comprising a second fluid channel; and a scaffold including a nanofiber membrane disposed between the first and second channel layers. The first and second channels cross each other.

IPC Classes  ?

  • C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
  • C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means

60.

PLANAR TRANSFORMER WITH FLEXIBLE TURN RATIO AND LEAKAGE INDUCTANCE INTEGRATION

      
Application Number 18613616
Status Pending
Filing Date 2024-03-22
First Publication Date 2024-09-26
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Zhu, Liyan
  • Li, Qiang

Abstract

An example power converter may include a planar transformer including a magnetic core, a primary winding, a first secondary winding interleaved with the primary winding, and a second secondary winding interleaved with the primary winding. The magnetic core may include a first core half, a second core half, multiple auxiliary legs formed by the first core half and the second core half, and multiple core legs formed by the first core half and the second core half. The multiple core legs may include a central core leg, and the primary winding may be wound around the central core leg among the two or more core legs. The planar transformer may be electrically coupled between a primary-side converter stage and a secondary-side converter stage.

IPC Classes  ?

  • H02M 1/00 - Details of apparatus for conversion
  • H01F 27/28 - CoilsWindingsConductive connections
  • H01F 27/38 - Auxiliary core membersAuxiliary coils or windings
  • H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only

61.

RECHARGEABLE SOLID STATE LITHIUM BATTERIES WORKING OVER A WIDE TEMPERATURE RANGE

      
Application Number 18681416
Status Pending
Filing Date 2022-08-06
First Publication Date 2024-09-19
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Madsen, Louis A.
  • Lin, Feng
  • Yu, Deyang

Abstract

Composite electrolytes are provided that are useful as a solid-state electrolyte in alkali metal batteries. in particular in lithium metal batteries over a wide temperature range. In some aspects. the composite electrolyte includes an alkali metal salt of an aromatic polyimide polymer: and an ionic liquid: wherein the composite is a solid at 25° C. and at a temperature of about 200° C. For example. a molecular ionic composite electrolyte containing 10 wt % PBDT and 90 wt % 1-ethyl-3-methylimidazolium trifluoromethane-sulfonate (EMImTfO) shows an E′ of ≈0.4 GPa and an ionic conductivity of ≈ 3.2 mS cm− at room temperature. In various aspects. batteries are also provided containing a composite electrolyte described herein. The electrolytes enable batteries that are more stable and exhibit less risk of fire or thermal runaway, even when operated at elevated temperatures. In some instances. the alkali metal is lithium and the alkali metal anode is a lithium anode.

IPC Classes  ?

  • H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
  • H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

62.

SECURITY SIGNATURES IN BINDING AGENT JETTING PARTS

      
Application Number 18598861
Status Pending
Filing Date 2024-03-07
First Publication Date 2024-09-12
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Rahman, Kazi Moshiur
  • Williams, Christopher B.

Abstract

Embodiments are described for forming regions of varying porosity within an additive manufacturing (AM) object through selective deposition of a binding agent during fabrication. Upon sintering, the selectively applied binding agent forms stochastic regions of porosity within the object that are not externally visible. In some implementations, embedded porous regions are selectively generated to form an identifier region that can be used as a unique part identification tag identifiable through non-destructive evaluation. The identifier tag may be useful in anti-counterfeiting security for parts fabricated through binding agent jetting (BT) and other additive manufacturing techniques.

IPC Classes  ?

  • B22F 10/14 - Formation of a green body by jetting of binder onto a bed of metal powder
  • B22F 10/64 - Treatment of workpieces or articles after build-up by thermal means
  • B33Y 10/00 - Processes of additive manufacturing
  • B33Y 40/20 - Post-treatment, e.g. curing, coating or polishing
  • B33Y 80/00 - Products made by additive manufacturing

63.

PERCEPTION QUALITY EVALUATION OF AN OBJECT DETECTION SYSTEM

      
Application Number US2024018128
Publication Number 2024/186651
Status In Force
Filing Date 2024-03-01
Publication Date 2024-09-12
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Eskandarian, Azim
  • Zhang, Ce

Abstract

Perception quality assessment concepts for an object detection system are described. An example method can include identifying true positive and/or false negative object detection data in object detection data generated by an object detection system based on an image. The method can also include generating a saliency map based on the image. The saliency map can include saliency intensity data corresponding to the image. The method can also include identifying true positive and/or false negative saliency intensity data in the saliency map based on the true positive and/or false negative object detection data, respectively. The method can also include calculating a perception quality metric (PQM) based on the true positive and/or false negative saliency intensity data. The PQM can be indicative of a degree of perception quality of the object detection system with respect to the image. The method can also include performing an operation based on the PQM.

IPC Classes  ?

  • G06V 10/70 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning
  • G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]
  • G06V 20/58 - Recognition of moving objects or obstacles, e.g. vehicles or pedestriansRecognition of traffic objects, e.g. traffic signs, traffic lights or roads
  • G06T 7/00 - Image analysis
  • B60W 50/00 - Details of control systems for road vehicle drive control not related to the control of a particular sub-unit

64.

REAL-TIME CONTROL OF LASER POWER FOR LASER POWDER BED FUSION

      
Application Number 18601199
Status Pending
Filing Date 2024-03-11
First Publication Date 2024-09-12
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Wang, Rongxuan
  • Standfield, Benjamin
  • Kong, Zhenyu
  • Dou, Chaoran

Abstract

An example feedback control system includes a laser powder bed fusion (L-PBF) platform including a laser. The L-BPF platform is configured to print a target object with the laser. The feedback control system includes a sensing system configured to measure an operative thermal emission index (TEI) emitted during print of the target object by the L-PBF platform. The feedback control system additionally includes a controller communicatively coupled to the sensing system. The feedback control signal is configured to determine an error based on a comparison between a control setpoint and the operative TEI, generate a control signal based on the error, and adaptively adjust a power of the laser during the print of the target object based on the control signal to maintain the control setpoint.

IPC Classes  ?

  • B22F 10/36 - Process control of energy beam parameters
  • B22F 12/90 - Means for process control, e.g. cameras or sensors
  • B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes

65.

CYCLED PULSING TO MITIGATE THERMAL DAMAGE FOR MULTI-ELECTRODE IRREVERSIBLE ELECTROPORATION THERAPY

      
Application Number 18608958
Status Pending
Filing Date 2024-03-19
First Publication Date 2024-09-12
Owner
  • Virginia Tech Intellectual Properties, Inc. (USA)
  • AngioDynamics, Inc. (USA)
Inventor
  • O'Brien, Timothy J.
  • Neal, Ii, Robert E.
  • Davalos, Rafael V.

Abstract

Methods and systems for distributing electrical energy to tissue which minimize Joule heating, thermal effects, and/or thermal damage, without sacrificing efficacy of treatment, are described. The methods and systems are particularly suitable to electrical energy-based therapies employing multiple electrodes, such as arrays of electrodes.

IPC Classes  ?

  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61B 17/00 - Surgical instruments, devices or methods
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents

66.

DATA DRIVEN SMART NON-PNEUMATIC TIRES

      
Application Number 18563246
Status Pending
Filing Date 2022-06-10
First Publication Date 2024-08-29
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Gupta, Utkarsh
  • Nalawade, Rajvardhan
  • Taheri, Saied

Abstract

Various embodiments of a smart non-pneumatic tire and methods for generating a mean vibration characteristic of the smart non-pneumatic tire are described. In one embodiment, a method for measuring the mean vibration characteristic includes receiving tire-road contact acceleration data from an accelerometer that is secured near a tire-surface contact region, where the tire-road contact acceleration data includes data captured by the accelerometer over a duration of time while a tread along an outer periphery of a sector of the tire contacts a surface. The method further includes receiving velocity data for the tire and load data for the tire over the duration of time. The method further includes generating a mean vibration characteristic based on the above-mentioned data. The method also includes changing a stiffness of spokes of the tire based on the generated mean vibration characteristic in some cases.

IPC Classes  ?

  • B60C 23/06 - Signalling devices actuated by deformation of the tyre
  • B60C 7/14 - Non-inflatable or solid tyres characterised by means for increasing resiliency using springs
  • G01M 17/02 - Tyres

67.

Methods of Additive Manufacturing by Direct Ink Writing of Emulsion Compositions

      
Application Number 18573837
Status Pending
Filing Date 2022-06-23
First Publication Date 2024-08-29
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Markvicka, Eric
  • Haake, Aaron
  • Bartlett, Michael D.
  • Tutika, Ravi Tej Anand
  • Schloer, Gwyneth

Abstract

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to methods of additive manufacture of emulsion compositions. In various aspects, the present disclosure relates to composite materials incorporating microstructures formed by inclusion compositions, and methods of their manufacture. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

IPC Classes  ?

  • C09D 11/023 - Emulsion inks
  • B29C 64/118 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
  • B29C 64/209 - HeadsNozzles
  • B29K 21/00 - Use of unspecified rubbers as moulding material
  • B29K 75/00 - Use of polyureas or polyurethanes as moulding material
  • B29K 83/00 - Use of polymers having silicon, with or without sulfur, nitrogen, oxygen or carbon only, in the main chain, as moulding material
  • B29K 105/16 - Fillers
  • B29K 505/00 - Use of metals, their alloys or their compounds, as filler
  • B33Y 10/00 - Processes of additive manufacturing
  • B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
  • B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
  • C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
  • C09D 11/322 - Pigment inks

68.

STRUCTURED DOCUMENT ACCESS FOR ELECTRONIC DOCUMENTS

      
Application Number 18585685
Status Pending
Filing Date 2024-02-23
First Publication Date 2024-08-29
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Fox, Edward A.
  • Ahuja, Aman
  • Ingram, William A.
  • Banerjee, Bipasha
  • Chekuri, Satvik

Abstract

Various examples are provided related to structured document access. In some examples, a structured documentation access service identifies a structured documentation request, processes structured documentation or electronic documents according to user selected options specified in the request, and generates a user interface to include subsection files, subsection summaries, object data including image-based objects and text-based objects, a result of an experiment defined by the request, or any combination thereof.

IPC Classes  ?

  • G06F 16/28 - Databases characterised by their database models, e.g. relational or object models
  • G06F 16/93 - Document management systems

69.

RARE-EARTH OXIDE COATINGS FOR REFRACTORY ALLOYS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME

      
Application Number US2024015780
Publication Number 2024/173541
Status In Force
Filing Date 2024-02-14
Publication Date 2024-08-22
Owner
  • UNIVERSITY OF VIRGINIA PATENT FOUNDATION (USA)
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Opila, Elizabeth J.
  • Hopkins, Patrick E.
  • Zhou, Bicheng
  • Balachandran, Prasanna
  • Tallon, Carolina

Abstract

(1-a-b-c-d...n)abc.n233(1), where the subscript "a" represents the molar fraction of element M2, "b" represents the molar fraction of element M3, "c" represents the molar fraction of element M4, and "n" represents molar fraction of element MN (in the metal oxide of formula (1)); and where the sum of a+b+c+d+..,+n is less than 1; where M1 represents a base element derived from a metal oxide that has a density of less than or equal to 7.0 grams per cubic centimeter, while M2, M3, M4,.. MN each represent a different element derived from the plurality of metal oxides each of which have a density greater than 7.0 g/cm3.

IPC Classes  ?

  • C01F 17/241 - Compounds containing only rare earth metals as the metal element oxide or hydroxide being the only anion containing two or more rare earth metals, e.g. NdPrO3 or LaNdPrO3
  • C04B 35/01 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides
  • C04B 35/622 - Forming processesProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products
  • C23C 18/12 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material
  • C23C 4/11 - Oxides
  • F01D 5/28 - Selecting particular materialsMeasures against erosion or corrosion

70.

DEVICES, SYSTEMS, AND METHODS FOR REAL-TIME MONITORING OF ELECTROPHYSICAL EFFECTS DURING TISSUE TREATMENT

      
Application Number 18404473
Status Pending
Filing Date 2024-01-04
First Publication Date 2024-08-22
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Davalos, Rafael V.
  • Bonakdar, Mohammad
  • Latouche, Eduardo L.
  • Mahajan, Roop L.
  • Robertson, John L.
  • Arena, Christopher B.
  • Sano, Michael B.

Abstract

Provided herein are devices, systems, and methods for monitoring lesion or treated area in a tissue during focal ablation or cell membrane disruption therapy.

IPC Classes  ?

  • A61B 5/0538 - Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
  • A61B 5/01 - Measuring temperature of body parts
  • G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals

71.

TREATMENT PLANNING SYSTEM FOR IMMUNOTHERAPY ENHANCEMENT VIA NON-THERMAL ABLATION

      
Application Number 18402231
Status Pending
Filing Date 2024-01-02
First Publication Date 2024-08-15
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Davalos, Rafael V.
  • White, Natalie

Abstract

Described herein are methods and systems of performing immunotherapy on a subject and/or determining if a subject will be responsive to ablation immunotherapy.

IPC Classes  ?

  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

72.

MULTI-AGENT COOPERATIVE PERCEPTION THROUGH PROBABILISTIC CLASSIFICATION MAP FUSION

      
Application Number US2024014612
Publication Number 2024/167915
Status In Force
Filing Date 2024-02-06
Publication Date 2024-08-15
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Mehr, Goodarz
  • Eskandarian, Azim

Abstract

Multi-agent cooperative perception concepts are described. An example method can include generating a first probabilistic classification map comprising a first probability that a state of a location in an external environment around a vehicle at a first time corresponds to at least one defined class. The method can also include obtaining a second probabilistic classification map comprising a second probability that the state of the location at a second time corresponds to the defined class(es). The method can also include calculating a third probability that the state of the location at a third time corresponds to the defined class(es) based on the first probability, the second probability, a difference in time between the first time and the third time, and a difference in time between the second time and the third time. The method can also include performing an operation associated with the vehicle based on the third probability.

IPC Classes  ?

  • G06F 18/24 - Classification techniques
  • G06V 20/58 - Recognition of moving objects or obstacles, e.g. vehicles or pedestriansRecognition of traffic objects, e.g. traffic signs, traffic lights or roads
  • G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
  • G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]

73.

BACTERIAL STRAINS THAT ENHANCE CROP LEGUME PLANT GROWTH

      
Application Number 18567887
Status Pending
Filing Date 2022-06-08
First Publication Date 2024-08-15
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Williams, Mark A.
  • Griggs, Roland
  • Sharaf, Hazem
  • Doyle, Connor

Abstract

Disclosed herein are compositions containing Pseudomonas strains referred to herein as Bullseye and Pancake and/or extracts from Pseudomonas strain cultures and methods of making and using the same. Also disclosed herein are methods for increasing crop legume plant growth using the disclosed compositions. The compositions are effective as well as environmentally benign and are not detrimental to human or animal health. Also disclosed are methods for extracting plant growth promoting rhizobacteria (PGPR) from nodules of a soybean plant.

IPC Classes  ?

74.

COMPOSITIONS AND METHODS FOR INDUCING IMMUNE RESPONSES AGAINST CLASS I FUSION PROTEIN VIRUSES

      
Application Number 17924963
Status Pending
Filing Date 2021-05-11
First Publication Date 2024-08-08
Owner
  • University of Virginia Patent Foundation (USA)
  • Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Zeichner, Steven L.
  • Meng, Xiang-Jin
  • Tian, Debin

Abstract

Provided are modified bacteria and derivatives thereof that express nucleotide sequence encoding an antigen of a viral family selected from the group comprising Retroviridae (e.g., HIV, including a HIV Fusion Peptide antigen), Orthomyxoviridae, Paramyxoviridae, Arenaviridae, 5 Filoviridae, and/or Coronaviridae (e.g., an SARS-CoV, SARS-CoV-2 Fusion Peptide, and/or PEDV). In some embodiments, the bacterium has a reduced genome and induces an enhanced immune response against the viral antigen of interest when administered to a subject. In some embodiments, the viral (e.g., SARS-CoV, 10 SARS-CoV-2, PEDV, and/or HIV) antigen is expressed on a surface of a bacterium. Also provided are method for producing antibodies against viral antigens, vaccine compositions, methods for vaccinating subjects, methods for treating viral infections in subjects, and expression vectors for expressing viral antigens including but not limited to coronavirus (e.g., SARS-CoV, SARS-CoV-2, and/or PEDV) antigens and/or HIV antigens on the surface of reduced 15 genome bacteria.

IPC Classes  ?

  • A61K 39/225 - Porcine transmissible gastroenteritis virus
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61P 31/14 - Antivirals for RNA viruses
  • C12N 1/20 - BacteriaCulture media therefor
  • C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
  • C12R 1/19 - Escherichia coli

75.

ENGINEERED S. TYPHIMURIUM AND USES THEREOF

      
Application Number 18578856
Status Pending
Filing Date 2022-07-12
First Publication Date 2024-08-01
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Behkam, Bahareh
  • Leaman, Eric

Abstract

Cancer is a significant cause of mortality and morbidity worldwide. One of the principal impediments to the broad success of conventional chemotherapy is poor delivery to and transport within the tumor microenvironment (TME), caused by irregular and leaky vasculature, the lack of functional lymphatics, and underscored by the overproduction of extracellular matrix (ECM) proteins such as collagen. Described herein are engineered Salmonella Typhimurium (S. Typhimurium) bacteria and uses thereof. In some embodiments, the engineered S. Typhimurium bacteria comprises an exogenous collagenase. Also described in exemplary embodiments herein methods of using the engineered S. Typhimurium bacteria, such as part of a,cancer therapy.

IPC Classes  ?

  • A61K 35/74 - Bacteria
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61P 35/00 - Antineoplastic agents
  • C12N 9/52 - Proteinases derived from bacteria
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

76.

LLAMA-DERIVED NANOBODIES BINDING THE SPIKE PROTEIN OF NOVEL CORONAVIRUS SARS-COV-2 WITH NEUTRALIZING ACTIVITY AND APPLICATION THEREOF

      
Application Number 18269156
Status Pending
Filing Date 2021-12-21
First Publication Date 2024-08-01
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Parreño, Gladys Viviana
  • Ibañez, Lorena Itati
  • Bok, Marina
  • Pavan, Florencia
  • Malito, Juan Pablo
  • Wigdorovitz, Andrés
  • Marcoppido, Gisela
  • Franco, Diego
  • Baumeister, Elsa
  • Schammas, Juan Manuel
  • Yuan, Lijuan
  • Auguste, Jonathan

Abstract

This disclosure is related to llama-derived nanobodies of which the corresponding sequences are provided, corresponding to the variable domain (VHH) of llama heavy chain antibodies recognizing epitopes of the Spike protein of SARS-COV-2, some of them, directed to the receptor binding domain, RBD. The nanobodies disclosed herein have important scientific significance and application prospects, they can be labeled or fused with fluorochromes and enzymes to be used as reagents for immunodetection of the virus. Most importantly, the disclosed nanobodies can be used in the development of a bio-drug for the prevention and clinical treatment of infection and diseases caused by SARS-COV-2.

IPC Classes  ?

  • C07K 16/10 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61P 31/12 - Antivirals

77.

NON-LINEAR BALLISTIC AND HYDRODYNAMIC ELECTRON TRANSPORT DEVICES AND METHODS

      
Application Number US2024011216
Publication Number 2024/151841
Status In Force
Filing Date 2024-01-11
Publication Date 2024-07-18
Owner
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
  • RENSSELAER POLYTECHNIC INSTITUTE (USA)
Inventor
  • Heremans, Jean J.
  • Kataria, Gitansh
  • Gupta, Adbhut
  • Morampudi, Manichandra
  • Sundararaman, Ravishankar

Abstract

The embodiments described herein are directed to various non-linear electrical devices in which charge flow is confined to two dimensions, so the charge flow occurs in what is called a two-dimensional system (2DS) or a two-dimensional electron system (2DES). A 2DS or 2DES can either exist in a natively two-dimensional material, such as graphene, potentially sandwiched between other materials, or in a quantum well sandwiched in semiconductor layers (e.g., a semiconductor heterostructure). A 2DS or 2DES can also be contained in certain threedimensional materials that enforce a predominantly two-dimensional charge flow. The devices exploit the non-linearity in current-voltage characteristics due to electron-electron interactions, either in the electronic ballistic or hydrodynamic transport regimes. The strength of the nonlinearity depends on the device geometry imposed on the 2DS or 2DES.

IPC Classes  ?

  • H01L 29/778 - Field-effect transistors with two-dimensional charge carrier gas channel, e.g. HEMT
  • B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
  • H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions

78.

SOLVENT-RESISTANT SELF-CROSSLINKED POLY(ETHER IMIDE)S

      
Application Number 18549998
Status Pending
Filing Date 2022-03-04
First Publication Date 2024-07-18
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Liu, Guoliang
  • Xu, Zhen
  • Esker, Alan Roger
  • Liu, Gehui

Abstract

In one aspect, the disclosure relates to azide-containing poly(ether imide) polymers (PEIs; N3-PEI-N3) synthesized via a heterogenous diazotizationazidation reaction. In one aspect, the azide-containing PEIs can be solution-cast into films and then thermally crosslinked. In a further aspect, the crosslinked PEIs (X-PEIs) exhibit superior thermal and mechanical properties. In a still further aspect, X-PEIs display outstanding resistance to classical solvents for conventional PEI, including THF, DCM, chloroform, DMF, and NMP. In another aspect, with an initial number average molecular weight (Mn) of 8.9 kDa, the disclosed azide-containing PEIs have a high crosslinking density and thus possess desirable thermal, mechanical, and solvent resistance properties.

IPC Classes  ?

  • C08J 5/18 - Manufacture of films or sheets
  • C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors
  • C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules

79.

SOLID-INFUSED SURFACES, ARTICLES INCORPORATING SOLID-INFUSED SURFACES, METHODS OF MAKING, AND METHODS OF USE THEREOF

      
Application Number 18559525
Status Pending
Filing Date 2022-05-07
First Publication Date 2024-07-18
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Pitchumani, Ranga
  • Stoddard, Ryan

Abstract

Solid-infused surfaces and articles having solid-infused surfaces are provided. The solid-infused surface includes (a) a substrate with a roughened surface having multi-scale surface roughness and a plurality of substrate asperities, and (b) a low surface-energy polymer coating a portion of the roughened surface forming the solid-infused surface having a fraction of the substrate asperities exposed on the solid-infused surface. The surfaces can be useful, in particular, for promoting condensation heat transfer performance. The articles and surfaces can include electronic components, optical components, or even pipes and other conduits for transporting certain fluids. Methods of making and methods of using the solid-infused surfaces are also provided.

IPC Classes  ?

  • C09D 5/16 - Anti-fouling paintsUnderwater paints
  • C23F 1/18 - Acidic compositions for etching copper or alloys thereof

80.

CONJUGATED LINOLEIC ACID SUPPLEMENTATION FOR DISEASE TREATMENT

      
Application Number 18289409
Status Pending
Filing Date 2022-05-04
First Publication Date 2024-07-18
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor Good, Deborah J.

Abstract

Described in certain example embodiments herein are methods of and compositions for treating a Snordl l6 deficiency disease or symptom thereof with conjugated linoleic acid (CLA) or a formulation thereof. In some embodiments, the Snordl l6 deficiency disease is Prader-Willi Syndrome. Described in certain example embodiments herein are methods of and compositions for treating Nhlh2 associated hypogonadism with CLA or a formulation thereof.

IPC Classes  ?

  • A61K 31/201 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having one or two double bonds, e.g. oleic or linoleic acid
  • A61P 1/14 - Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61P 5/24 - Drugs for disorders of the endocrine system of the sex hormones

81.

ENCODING AND DECODING OF INFORMATION FOR WIRELESS TRANSMISSION USING MULTI-ANTENNA TRANSCEIVERS

      
Application Number 18398982
Status Pending
Filing Date 2023-12-28
First Publication Date 2024-07-11
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • O'Shea, Timothy James
  • Erpek, Tugba

Abstract

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training and deploying machine-learned communication over multi-input-multi-output (MIMO) channels. One of the methods includes: determining a transmitter and a receiver, at least one of which implements a machine-learning network; determining a MIMO channel model; determining first information; using the transmitter to process the first information and generate first RF signals representing inputs to the MIMO channel model; determining second RF signals representing outputs of the MIMO channel model, each second RF signal representing aggregated reception of the first RF signals altered by transmission through the MIMO channel model; using the receiver to process the second RF signals and generate second information as a reconstruction of the first information; calculating a measure of distance between the second and first information; and updating the machine-learning network based on the measure of distance between the second and first information.

IPC Classes  ?

  • H04B 7/0452 - Multi-user MIMO systems
  • G06N 3/006 - Artificial life, i.e. computing arrangements simulating life based on simulated virtual individual or collective life forms, e.g. social simulations or particle swarm optimisation [PSO]
  • G06N 3/044 - Recurrent networks, e.g. Hopfield networks
  • G06N 3/045 - Combinations of networks
  • G06N 3/048 - Activation functions
  • G06N 3/08 - Learning methods
  • G06N 3/082 - Learning methods modifying the architecture, e.g. adding, deleting or silencing nodes or connections
  • G06N 3/086 - Learning methods using evolutionary algorithms, e.g. genetic algorithms or genetic programming
  • G06N 3/088 - Non-supervised learning, e.g. competitive learning
  • H04B 7/0413 - MIMO systems
  • H04B 7/06 - Diversity systemsMulti-antenna systems, i.e. transmission or reception using multiple antennas using two or more spaced independent antennas at the transmitting station

82.

SMALL-SCALE SOLID-STATE ADDITIVE MANUFACTURING TOOLS AND DESIGNS

      
Application Number US2024010061
Publication Number 2024/148020
Status In Force
Filing Date 2024-01-02
Publication Date 2024-07-11
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES (USA)
Inventor
  • Gottwald, Ryan
  • Yu, Hang Z.

Abstract

An apparatus may include a modular tool positioned in a spaced apart relationship with a rotatable head holding a feed rod for additive manufacturing, the modular tool comprising: a first portion having a first aperture that slidably allows the feed rod to pass through, a second portion coupled with the first portion, the second portion having a second aperture aligned with the first aperture, the second aperture slidably allows the feed rod to pass through, the second portion having a melting point that is less than the melting point of the first portion, a bearing coupled with at least one of the first portion or the second portion.

IPC Classes  ?

  • B23K 20/12 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating the heat being generated by frictionFriction welding
  • B22F 12/00 - Apparatus or devices specially adapted for additive manufacturingAuxiliary means for additive manufacturingCombinations of additive manufacturing apparatus or devices with other processing apparatus or devices
  • B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
  • B29C 64/227 - Driving means
  • B29C 64/321 - Feeding
  • B22F 12/50 - Means for feeding of material, e.g. heads

83.

METHODS OF ISOLATING EXOSOMES

      
Application Number 18547489
Status Pending
Filing Date 2022-02-23
First Publication Date 2024-07-11
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Marsh, Spencer
  • Pridham, Kevin J.
  • Jourdan, Linda Jane
  • Gourdie, Robert G.

Abstract

Described in certain example embodiments herein are methods of isolating exosomes from a biological fluid, such as those containing caseins.

IPC Classes  ?

84.

INTEGRATED THERMAL CONTROL FOR ADDITIVE MANUFACTURING AND COATING

      
Application Number 18563255
Status Pending
Filing Date 2022-05-26
First Publication Date 2024-07-04
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Griffiths, Robert J.
  • Garcia, David
  • Yu, Hang

Abstract

A system and method for additive manufacturing are described. A system includes an additive manufacturing tooling head configured to deposit a heated material to form a workpiece, a tooling controller configured direct the tooling head through a sequence of additive manufacturing process actions, and a chamber comprising a build surface to support the workpiece during the sequence of additive manufacturing process actions. At least one thermal medium is positioned within the chamber. The tooling controller is further configured to determine a thermal gradient between the workpiece and the portion of the heated material based on the temperature of the workpiece and the temperature of the portion of the heated material to be deposited, and control the at least one thermal medium contained within the chamber over time based at least in part on a predetermined thermal gradient range.

IPC Classes  ?

  • B29C 64/393 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
  • B29C 64/295 - Heating elements
  • B29C 64/364 - Conditioning of environment
  • B33Y 10/00 - Processes of additive manufacturing
  • B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
  • B33Y 40/20 - Post-treatment, e.g. curing, coating or polishing
  • B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes

85.

METHODS TO PRODUCE HIGH STRENGTH ALUMINUM AND HIGH-STRENGTH ALUMINUM ARTICLES PRODUCED THEREFROM

      
Application Number US2023080397
Publication Number 2024/144945
Status In Force
Filing Date 2023-11-17
Publication Date 2024-07-04
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Yoder, Jake
  • Hahn, Greg
  • Yu, Hang Z.

Abstract

Methods of making high-strength aluminum and high-strength aluminum articles made therefrom are provided. The methods include high strain rate severe plastic deformation (SPD) process applied to aluminum alloys containing aluminum and one or more of copper, magnesium, and zinc and being substantially free of chromium, zirconium, and manganese.

IPC Classes  ?

  • C22F 1/047 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon of alloys with magnesium as the next major constituent
  • B23K 20/12 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating the heat being generated by frictionFriction welding
  • C22C 21/16 - Alloys based on aluminium with copper as the next major constituent with magnesium

86.

NUCLEAR REACTOR CORE WITH ROTATING FUEL MODULES AND RELATED SYSTEMS

      
Application Number 18557439
Status Pending
Filing Date 2022-04-29
First Publication Date 2024-06-27
Owner
  • Ohio State Innovation Foundation (USA)
  • Virginia Tech Intellectual Properties, Inc (USA)
  • Jacksonville University (USA)
  • The University of Maryland (USA)
Inventor
  • Smidts, Carol
  • Haghighat, Alireza
  • Aldemir, Tunc
  • Aydogan, Fatih
  • Khafizov, Marat
  • Horack, John
  • Cao, Lei Raymond
  • Zhao, Ji-Cheng

Abstract

Nuclear reactor cores and related systems are described herein. An example nuclear reactor core includes a plurality of fuel modules, where each of the plurality of fuel modules includes nuclear fuel; at least one fuel-module actuator mechanically coupled to at least one of the plurality of fuel modules, where the at least one fuel-module actuator is configured to rotate the at least one of the plurality of fuel modules; and at least one neutron source configured to emit neutrons and trigger a fission chain reaction in the at least one of the plurality of fuel modules.

IPC Classes  ?

  • G21C 7/30 - Control of nuclear reaction by displacement of reactor fuel or fuel elements
  • G21C 3/40 - Structural combination of fuel element with thermoelectric element for direct production of electric energy from fission heat
  • G21C 5/16 - Shape of its constituent parts

87.

IMPLANT DEVICE FOR PLANTAR REPAIR

      
Application Number 18555383
Status Pending
Filing Date 2022-05-04
First Publication Date 2024-06-27
Owner
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
  • CARILION CLINIC (USA)
Inventor
  • Poulos, Demitria
  • Dickinson, Logan N.
  • Carlson, Skye
  • Kozar, Zachary
  • Wayne, Jennifer S.
  • Wang, Vincent
  • Clements, John R.

Abstract

Various aspects of an implant for plantar plate repair and a surgical method of plantar plate repair using the implant are described. In one example, the implant includes a female component and a male component. The female component includes an open barrel having an outer surface and an inner surface, a flange cap at one end of the open barrel, and a recessed tiedown bar that extends between openings through the flange cap. The openings through the flange cap extending into the open barrel of the female component. The male impant includes an open barrel portion, a pair of fingers extending from one end of the open barrel portion, and a flange cap at another end of the open barrel portion. The male implant also includes an opening through the flange cap, extending into the open barrel portion of the male implant.

IPC Classes  ?

88.

REAL-TIME INTERFERENCE MITIGATION METHOD FOR AUTOMOTIVE RADAR

      
Application Number US2023073467
Publication Number 2024/129227
Status In Force
Filing Date 2023-09-05
Publication Date 2024-06-20
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Wu, Yubo
  • Hou, Y. Thomas

Abstract

Real-time vehicle radar interference mitigation concepts are described. In one embodiment, a method to mitigate interference for a vehicle radar includes detecting a target object in a vicinity of a vehicle. The detection of the target object generates an intended signal. The method further includes detecting an interference signal in the vicinity of the vehicle and receiving a return signal that includes the intended signal and the interference signal. The method further includes transforming the return signal to a frequency-time domain return signal using a short-time Fourier transform, determining a reconstructed interference signal in a frequency-time domain, transforming the reconstructed interference signal to a time domain, and removing the interference signal in the time domain from the return signal to isolate the intended signal based on the reconstructed interference signal in the time domain. The method further includes employing a parallel and computational efficient structure to deliver real-time output.

IPC Classes  ?

  • G01S 13/93 - Radar or analogous systems, specially adapted for specific applications for anti-collision purposes
  • G01S 13/56 - Discriminating between fixed and moving objects or between objects moving at different speeds for presence detection
  • G01S 7/02 - Details of systems according to groups , , of systems according to group

89.

NOVEL PROCESS AND FLOTATION CHEMISTRY FOR VALUABLE METAL RECOVERY FROM MUNICIPAL SOLID WASTE INCINERATION (MSWI) ASH

      
Application Number 18514620
Status Pending
Filing Date 2023-11-20
First Publication Date 2024-06-20
Owner
  • Phinix, LLC (USA)
  • Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Das, Subodh
  • Zhang, Wencai

Abstract

The present disclosure concerns processes and the combinations thereof for the enrichment and/or isolation of valuable metals from municipal solid waste incineration (MSWI) ash. Included are processes of size separation, froth floatation, magnetic separation, specific gravity separation, chemical separation, as well as the removal of lime. BY utilizing two or more, circuits of treatment are also provided that allow for fractionation of enriched valuable metals(s) from which purification thereof can be readily achieved.

IPC Classes  ?

  • C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof
  • C22B 1/24 - BindingBriquetting

90.

TRANSIENT CONTROL SCHEME FOR MULTIPHASE POWER CONVERTERS

      
Application Number 18068144
Status Pending
Filing Date 2022-12-19
First Publication Date 2024-06-20
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Naradhipa, Adhistira Madhyasta
  • Li, Qiang

Abstract

Aspects of a transient control scheme for a multiphase power converter are described. In one example, a power converter system includes a multiphase power converter that includes a plurality of converter phases, with each converter phase comprising a switching transistor and an inductor coupled between an input power source and a load. The power converter system also includes a controller configured to distribute an on-time signal to each converter phase during operation of the multiphase power converter. The controller includes circuitry configured to enable an on-time signal phase overlap between non-subsequent phases of the multiphase power converter when a load current increase is detected during a transient state of the multiphase power converter. The on-time signal phase overlap refers to a simultaneous on-state of two or more switching transistors of the non-subsequent phases during a duration of time within the transient state.

IPC Classes  ?

  • H02M 1/14 - Arrangements for reducing ripples from DC input or output
  • H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load

91.

GALOIS EXTENSION FIELD-BASED BLOCK CIPHER

      
Application Number 18287547
Status Pending
Filing Date 2022-04-19
First Publication Date 2024-06-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Michaels, Alan J.
  • George, Kiernan B.

Abstract

Various examples are provided related to a block cipher adaptation of the Galois Extension Fields (GEF) combination technique. In one example, a GEF-based block encryption includes forming an output from a PRNG into a key matrix, where the key matrix is formatted as an invertible square matrix; applying a GEF operation to the key matrix to map elements to a closed subset in a higher-order GEF space; mapping plaintext to a plaintext matrix; applying a GEF operation to the plaintext matrix to map elements to the higher-order GEF space; combining the plaintext matrix and the key matrix to produce a vector of ciphertext in the higher-order GEF space; reducing the vector to a reduced vector of ciphertext using an inverse of the GEF operation; and during the reducing, applying a ceiling operation to bijectively map elements in the reduced vector to a closed subset. Another example includes GEF-based block decryption.

IPC Classes  ?

  • H04L 9/06 - Arrangements for secret or secure communicationsNetwork security protocols the encryption apparatus using shift registers or memories for blockwise coding, e.g. D.E.S. systems

92.

HETEROGENEOUS SUPERJUNCTION DEVICES

      
Application Number 18486883
Status Pending
Filing Date 2023-10-13
First Publication Date 2024-06-06
Owner Virginia Tech Intellectual Properties, Inc. (USA)
Inventor
  • Zhang, Yuhao
  • Xiao, Ming
  • Ma, Yunwei

Abstract

A device may include a substrate of a first conductivity type, the first conductivity type being one of a n-type conductivity and a p-type conductivity, the substrate having a base surface. A device may include a first terminal coupled with the base surface of the substrate, a first semiconductor region disposed over the substrate, the substrate positioned between the first semiconductor region and the first terminal, the first semiconductor region including a top surface, which defines a plurality of trenches having sidewalls, the plurality of trenches separated by a plurality of pillars, the first semiconductor region formed of a first material with the first conductivity type, a second semiconductor region disposed over the sidewalls of the first semiconductor region to form a superjunction with the first semiconductor region, the second semiconductor region formed of a second material different from the first material and having a second conductivity type.

IPC Classes  ?

  • H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions
  • H01L 29/78 - Field-effect transistors with field effect produced by an insulated gate
  • H01L 29/80 - Field-effect transistors with field effect produced by a PN or other rectifying junction gate
  • H01L 29/861 - Diodes
  • H01L 29/872 - Schottky diodes

93.

TESTING AND EDUCATION MICROREACTOR

      
Application Number 18549440
Status Pending
Filing Date 2022-04-29
First Publication Date 2024-06-06
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor Haghighat, Alireza

Abstract

A configurable microreactor for testing and education is described. The microreactor includes a reactor core comprising a plurality of fuel rods, a plurality of guide tubes, and a plurality of rotating control drums configured to control operation of the microreactor. Further, the microreactor includes a testing cavity disposed in an area within the reactor configured to store an item therein for experimentation; a plurality of beam ports; a moveable particle filter ring; a moveable spectrum shifter; and at least one sensor. A computing device is directed to receive measurements from the at least one sensor and perform a physics-based analysis of the microreactor using one or more machine learning (ML) routines.

IPC Classes  ?

  • G21C 17/00 - MonitoringTesting
  • G09B 23/20 - Models for scientific, medical, or mathematical purposes, e.g. full-sized device for demonstration purposes for physics for atomic physics or nucleonics
  • G21C 17/104 - Measuring reactivity
  • G21C 17/112 - Measuring temperature

94.

DOUBLE-SIDE COOLED POWER MODULES

      
Application Number 18549447
Status Pending
Filing Date 2022-03-14
First Publication Date 2024-05-30
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Lu, Guo-Quan
  • Zhang, Zichen

Abstract

Multi-chip module packaging technologies for GaN and other devices are described. The power module packaging technology described can be applied to all types of medium-voltage devices, such as silicon (Si), silicon carbide (SiC), gallium nitride (GaN), or the latest gallium oxide (Ga2O3) devices. In one example, a power module includes a first substrate, a second substrate, a sintered-silver semiconductor die pillar, the pillar being positioned between the first substrate and the second substrate, a terminal on a first side of the power module, and a terminal on a second side of the power module.

IPC Classes  ?

  • H01L 23/498 - Leads on insulating substrates
  • H01L 21/48 - Manufacture or treatment of parts, e.g. containers, prior to assembly of the devices, using processes not provided for in a single one of the groups or
  • H01L 23/00 - Details of semiconductor or other solid state devices
  • H01L 23/373 - Cooling facilitated by selection of materials for the device
  • H01L 25/00 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices
  • H01L 25/07 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in subclass

95.

HIGH-VISCOSITY RESINS IN MASK PROJECTION STEREOLITHOGRAPHY

      
Application Number 18550847
Status Pending
Filing Date 2022-03-17
First Publication Date 2024-05-30
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Rau, Daniel A.
  • Williams, Christopher B.

Abstract

A method for fabricating an item using a high-viscosity photoresin is described that includes providing tooling that comprises an extruder and a light source: depositing. by the extruder of the tooling. a first non-patterned layer of the high-viscosity photoresin: selectively photocuring. by the light source of the tooling. the first non-patterned layer into a first predetermined layer shape: depositing. by the extruder of the tooling. a second nonpatterned layer of the high-viscosity photoresin: and selectively photocuring. by the light source of the tooling. the second non-patterned layer into a second predetermined layer shape.

IPC Classes  ?

  • B29C 64/129 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask
  • B29C 64/209 - HeadsNozzles
  • B29C 64/286 - Optical filters, e.g. masks
  • B29C 64/393 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
  • B33Y 10/00 - Processes of additive manufacturing
  • B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
  • B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
  • B33Y 70/00 - Materials specially adapted for additive manufacturing

96.

SYSTEM AND METHOD FOR ABLATING A TISSUE SITE BY ELECTROPORATION WITH REAL-TIME MONITORING OF TREATMENT PROGRESS

      
Application Number 18528051
Status Pending
Filing Date 2023-12-04
First Publication Date 2024-05-30
Owner
  • Virginia Tech Intellectual Properties Inc. (USA)
  • AngioDynamics, Inc. (USA)
Inventor
  • Neal, Ii, Robert
  • Davalos, Rafael V.

Abstract

A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.

IPC Classes  ?

  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
  • A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
  • C12N 13/00 - Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

97.

A NOVEL PROCESS AND FLOTATION CHEMISTRY FOR VALUABLE METAL RECOVERY FROM MUNICIPAL SOLID WASTE INCINERATION (MSWI) ASH

      
Application Number US2023080543
Publication Number 2024/112673
Status In Force
Filing Date 2023-11-20
Publication Date 2024-05-30
Owner
  • PHINIX, LLC (USA)
  • VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Das, Subodh
  • Zhang, Wencai

Abstract

The present disclosure concerns processes and the combinations thereof for the enrichment and/or isolation of valuable metals from municipal solid waste incineration (MSWI) ash. Included are processes of size separation, froth floatation, magnetic separation, specific gravity separation, chemical separation, as well as the removal of lime. BY utilizing two or more, circuits of treatment are also provided that allow for fractionation of enriched valuable metals(s) from which purification thereof can be readily achieved.

IPC Classes  ?

  • B09B 3/00 - Destroying solid waste or transforming solid waste into something useful or harmless
  • C04B 18/04 - Waste materialsRefuse
  • A62D 3/33 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by chemically fixing the harmful substance, e.g. by chelation or complexation
  • A62D 3/30 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents

98.

IN-FIBER OPTICAL MICRORESONATORS AND COUPLERS

      
Application Number 18549439
Status Pending
Filing Date 2022-03-31
First Publication Date 2024-05-16
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Yang, Shuo
  • Wang, Anbo

Abstract

A method for forming an optical fiber having at least one of a microresonator and a coupler integrated therein is described. The method includes providing an optical fiber having a light guiding core. modifying at least one region of the optical fiber using a laser, immersing the optical fiber having the at least one region as modified inside an etchant that selectively etches the at least one region as modified to generate at least one of a microresonator and a coupler integrated in the optical fiber, and removing the optical fiber from the etchant. The optical fiber as removed from the etchant may include the at least one of the microresonator and the coupler. The method may further include heating the optical fiber using, for example, a CO2 laser or other heating apparatus, to smoothen surface irregularities of at least one of the microresonator and the coupler.

IPC Classes  ?

  • G02B 6/293 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means

99.

METHODS AND APPARATUS FOR EVAPORATION BASED LIQUID TRANSPORT

      
Application Number 18281503
Status Pending
Filing Date 2022-03-11
First Publication Date 2024-05-09
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Cheng, Jiangtao
  • He, Xukun

Abstract

This disclosure provides an apparatus, including a first plate having a first transport surface and a second plate having a second transport surface. The second plate is positioned at an acute angle with respect to the first plate such that a first transport surface of the first plate faces the second transport surface of the second plate. The first transport surface and the second transport surface are hydrophobic. The apparatus also includes one or more liquid droplets positioned between and in contact with the first transport surface and the second transport surface. During evaporation, the liquid droplet will automatically move towards the cusp of the first plate and the second plate.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

100.

DOUBLE-SIDE COOLED POWER MODULES WITH SINTERED-SILVER INTERPOSERS

      
Application Number 18549443
Status Pending
Filing Date 2022-03-11
First Publication Date 2024-05-09
Owner VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (USA)
Inventor
  • Lu, Guo-Quan
  • Ding, Chao

Abstract

Planar, double-side cooled half-bridge power modules using sintered-silver interposers and all sintered-silver joints are described. Thermo-mechanical simulations showed that use of the sintered-silver interposers reduce the thermo-mechanical stresses at vulnerable interfaces as compared to using solid copper interposers. The porous sintered-silver interposers are also easily deformable under a low load, which improves the yield of module interconnections in the presence of imperfections caused by variations in die thickness, interposer height, and substrate distortion. Results on the electrical performance of the modules validate the fabrication approach for the modules, for making high power-density converters with reliable operations at high junction temperatures.

IPC Classes  ?

  • H01L 23/498 - Leads on insulating substrates
  • H01L 23/00 - Details of semiconductor or other solid state devices
  • H01L 23/528 - Layout of the interconnection structure
  • H01L 29/16 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only elements of Group IV of the Periodic System in uncombined form
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