The invention refers to a catheter assembly (11) comprising a tubular inner workpiece (12) with an inner lumen (13) and a tubular outer workpiece (14). For a cost-effective manufacturing of such catheter assembly (11) in which the inner workpiece (12) is attached to the outer workpiece (14), the assembly (11) further comprises an elongate insert (30) with a U-shaped and/or V-shaped first section (31) and a second section (32) located adjacent to the first section (31) in longitudinal direction, wherein an inner surface (35, 38) of a first end portion (31a) of the first section (31) is configured to support an end section of the inner workpiece (12). Further, the end section of the inner workpiece (12) is attached to the inner surface (35, 38) of the first end portion (31a) of the first section (31) of the insert (30), wherein the outer workpiece (14) covers the inner workpiece (12) and the insert (30) except for a cutout in the wall of the outer workpiece (14) providing access to the inner lumen (13) of the inner workpiece (12), wherein the outer workpiece (14) is attached along and/or near an edge (15, 15a, 15b, 15c) of the cutout to the inner workpiece (12) and to the outer surface of the insert (30) in the first section (31) and in the second section (32) of the insert (30). The invention further refers to a method for manufacturing of such catheter assembly (11), a respective catheter (10) and a preparation method of such catheter (10).
A catheter system includes a rolling membrane guiding catheter and a docking unit. The docking unit is configured to automatically insert a plurality of devices into the rolling membrane guiding catheter.
A process for producing a hollow cylinder for an implant includes extruding a blank that is at least partially inserted into a recipient chamber of a recipient by pressing a punch through a die or by pressing both the punch and the die both into the recipient. A mandrel is drive into the blank to form a hollow cylinder with an inside diameter defined by the mandrel and an outside diameter defined by the die. The hollow cylinder is guided through a roll gap defined by at least two rollers.
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
B21C 1/24 - Metal drawing by machines or apparatus in which the drawing action is effected by means other than drums, e.g. by a longitudinally-moved carriage pulling or pushing the work or stock for making metal sheets, rods or tubes specially adapted for making tubular articles by means of mandrels
The invention relates to a catheter system for carrying out an angioplasty, comprising an outer shaft which extends in an axial direction and has a distal end, an inner shaft which can be moved therein in the axial direction and has a distal end, and a rolling membrane which is connected to the distal end of the outer shaft and the distal end of the inner shaft in a pressure-tight manner, and which can be moved between a rolled-in position within the outer shaft and a position in which it is rolled out distally from the outer shaft by applying pressure.
The invention relates to a simple and cost-effective method of manufacturing a catheter assembly (10, 110) or stent assembly by joining a first tubular component (11, 111) and at least a second component (12, 112), wherein the joining is provided in a joining section (15) of the first tubular component (11, 111), wherein the method comprises the following steps: - Providing the first tubular component (11, 111) and the at least one second component (12, 112), - Arranging at least a portion of the at least one second component (12, 112) adjacent the first tubular component (11, 111) in its joining section (15), - Arranging the catheter assembly (10, 110) or the stent assembly within a stretchable tube (20), - Stretching the tube (20) axially such that the diameter of the tube (20) is reduced thereby providing a joining pressure to the catheter assembly (10, 110) or stent assembly at the joining section (15) in this stretched condition, - Arranging the catheter assembly (10, 110) or stent assembly and the tube (20) within and/or at a heating unit (22, 28), - Heating the catheter assembly (10, 110) or stent assembly at and/or near the joining section (15) by the heating unit (22, 28) thereby creating a substance-to-substance bond between the first tubular component (11, 111) and the at least one second component (12, 112) at the joining section (15) while the tube (20) is in its stretched condition, - Subsequently, transferring the tube (20) from its stretched condition to a released condition and removing the catheter assembly (10, 110) or stent assembly from the tube (20) and the heating unit (22, 28). The invention further relates to a respective manufacturing device as well as to a respective catheter assembly, stent assembly and implant.
B29C 65/68 - Joining of preformed partsApparatus therefor by liberation of internal stresses, e.g. shrinking of one of the parts to be joined using auxiliary shrinkable element
B29C 65/00 - Joining of preformed partsApparatus therefor
6.
Synthesis and Characterization of Cyclic Hydrocarbon Esters of Everolimus
Generally, the field of synthesis, formulations and perivascular treatment methods involving cyclic ester derivatives of everolimus. More specifically, a method of treating open vascular surgical manipulations comprising administering an effective amount of the rapamycin 40-O-cyclic hydrocarbon ester compound, preferably by direct perivascular application, wherein the compound is preferably formulated to allow for direct perivascular application directly to graft vessels upon initiation of surgery.
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
Medical guide wires, medical insertion sleeves, parts and
accessories for the above-mentioned products; mechanical
components for medical use for extending the lifespan and
effectiveness of the above-mentioned medical devices and
used as therapeutic means for disease treatment.
iHH aFF iHH H of the hollow cylinder. The invention further relates to the use of said honing tool in a honing machine, to the use thereof in a honing method, and to the resulting product.
B24B 33/02 - Honing machines or devicesAccessories therefor designed for working internal surfaces of revolution, e.g. of cylindrical or conical shapes
9.
COEXTRUDED OUTER SHAFT DESIGN FOR ROLLING MEMBRANE CATHETERS
A rolling membrane catheter (100) comprises a rolling membrane (120) and a coextruded outer shaft (130) comprising an inner layer (132) and an outer layer (134). A method for coextruding a coextruded outer shaft comprises coextruding an outer shaft and attaching a rolling membrane to the outer shaft.
Medical catheters, surgical catheters, catheters for use in
vascular procedures, balloon catheters, parts and
accessories for the above-mentioned products; mechanical
components of the above-mentioned medical apparatus, being
integral parts of such apparatus and used for therapeutic
purposes for disease treatment.
Medical catheters, surgical catheters, catheters for use in
vascular procedures, support catheters, guide catheters,
guide-wire extension catheters, balloon catheters, medical
guide-wires, insertion sleeves, parts and accessories for
the above-mentioned products; all the above-mentioned goods
are not intended for diagnostic purposes.
Medical catheters, surgical catheters, catheters for use in
vascular procedures, balloon catheters, parts and
accessories for the above-mentioned products.
A method for joining at least a first and a second component of a catheter using a clamping tool and heat treatment, without the use of heat shrink tubing. A device for joining at least two catheter components of a catheter includes or consists of: a clamping tool, a heating device, and optionally a cooling device. A (heat shrink tubing-free) catheter or catheter part, preferably a guide wire exit port, can be obtained by joining of at least two catheter components of the catheter by using the device or and/or the method.
An implant delivery system for implanting an implant for reducing a luminal diameter of a vessel, including: an implant being configured to be anchored to an inner wall (W) of the vessel (V) and to contract so as to reduce the luminal diameter of the vessel (V), and a catheter including a catheter sheath and an expansion device for expanding and deploying the implant at an implantation side in the vessel (V).
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
The present invention relates to a catheter system (1) for closing the left atrial appendage (2), comprising: a first catheter (10) comprising a balloon (12) for temporarily sealing the left atrial appendage (2), and a second catheter (20) having a distal section (22a) that accommodates an adhesive (30), wherein the second catheter (20) is configured to be inserted into a lumen (14) of the first catheter (10) and to slide therein to apply the filling material to the collapsed left atrial appendage (2).
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
16.
DILATOR TIP DESIGN FOR ENHANCED FORCE TRANSMISSION
A dilator including a shaft and a reinforcing element. The reinforcing element is connected to a distal end of the shaft. The reinforcing element is in contact with the distal end of the dilator shaft and the connection element. The connection element at least in part encloses the dilator shaft and/or the reinforcing element. The connection element extends into at least one indentation recess or through hole of the reinforcing element. The connection element consists of a polymer. The reinforcing element consists of a metal or metal alloy.
The present invention relates to a guidewire (1), particularly for a catheter, comprising: a distal end section (1a), a functional element (2), wherein the functional element (2) is arranged on the distal end section (1a) and is configured to be deployed in a radial direction (R) of the guidewire (1) from an initial state to an expanded state for expanding a calcified stenosis of a vessel (V).
Medical catheters, surgical catheters, catheters for use in vascular procedures, support catheters, guide catheters, guide-wire extension catheters, balloon catheters, medical guide-wires, insertion sleeves, parts and accessories for the above-mentioned products; all the above-mentioned goods are not intended for diagnostic purposes.
Medical catheters, surgical catheters, catheters for use in vascular procedures, balloon catheters, parts and accessories for the above-mentioned products.
Medical guide wires, medical insertion sleeves, parts and accessories for the above-mentioned products; mechanical components for medical use for extending the lifespan and effectiveness of the above-mentioned medical devices and used as therapeutic means for disease treatment.
A catheter includes an outer shaft, an inner shaft, a rolling membrane and an inflatable element that defines an inflatable volume. The inner shaft includes an inner shaft lumen and the inner shaft is at least partially arranged within the outer shaft. The rolling membrane is connected to the outer shaft. The inflatable element includes at least two proximal ends connected to the inner shaft and at least one distal end connected to the rolling membrane.
A sleeve for a catheter includes a plurality of webs that extend in a longitudinal direction and are connected to one another by an undulating web in a circumferential direction to form a main web. A through gap is in least one web of the plurality of webs, and the at least one web extends in the longitudinal direction away from the gap on each side of the gap. A bridge web is connected to the at least one web only distally and proximally to the at least one web on each side of the gap. The bridge web is free to flare in the circumferential direction.
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/962 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
23.
HYDROPHILIC COATINGS FOR VASCULAR MEDICAL PRODUCTS
A hydrophilic coating for coating a surface of a vascular medical product. The copolymer includes repeating units of (a) vinylpyrrolidone, and (b) perfluorophenylazide. The copolymer can have a statistical distribution of the repeating units (a) and (b) and a molecular weight of 5,000 to 50,000 g/mol. The coating can be applied and then dried or radiated with UV radiation.
A guiding catheter includes an outer shaft defining a first guiding lumen in an interior of the outer shaft. An inner shaft is movably arranged at least partially in the first guiding lumen. The inner shaft defines a second guiding lumen in an interior of the inner shaft. A dividing device is arranged at a proximal end region of the guiding catheter. The dividing device includes a first port, and a second port angularly arranged with respect to each other. Both the first port and the second port provide access to the first guiding lumen. The inner shaft extends through the second port into the first guiding lumen. The inner shaft includes at least a section-wise slit along a longitudinal extension direction (F) of the inner shaft. The slit provides access to the second guiding lumen and enables a working catheter to enter the second guiding lumen from the first guiding lumen. The inner shaft has a length exceeding a length of the outer shaft.
The present invention relates to a covered stent comprising bacterial nanocellulose (BNC) and a method as well as an apparatus for producing the covered stent.
B05C 9/00 - Apparatus or plant for applying liquid or other fluent material to surfaces by means not covered by groups , or in which the means of applying the liquid or other fluent material is not important
B05D 1/00 - Processes for applying liquids or other fluent materials
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
C12P 19/00 - Preparation of compounds containing saccharide radicals
C12M 1/00 - Apparatus for enzymology or microbiology
B05C 13/02 - Means for manipulating or holding work, e.g. for separate articles for particular articles
C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
C12M 3/06 - Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
C12P 19/04 - Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
A catheter includes a medical bypass implant having a first end, a second end, and a body forming a flow lumen. A catheter shaft defines an inner lumen and a distal end. The inner lumen receives the medical implant in a delivery state such that the first end is arranged near to the distal end and the second end is arranged proximally from the first end. The catheter shaft is moved towards a vessel wall to place the first end on the vessel wall. An actuating catheter is received in the inner lumen. A tip thereof is operatively connected to the second end. The actuating catheter moves the second end towards the first end. The tip is configured to penetrate the vessel wall and to move the second end of the medical implant through the vessel wall.
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
A61B 17/00 - Surgical instruments, devices or methods
A catheter system for a interventional procedure includes a bendable and/or steerable extension arm and a guiding sheath. The extension arm is movable along the sheath or fixed at the distal end so that it projects in an operation position from the distal end. The extension arm has an inner guidewire lumen. At least one alignment component having a collapsed state and being configured to expand into an expanded state is advanceable to or attached to the guiding sheath at a pre-defined position within the distal section but proximally from its distal end. The alignment component includes a plurality of struts distributed on the circumference. Each strut of the struts runs at least sectionwise into radial direction and/or is inclined with regard to the longitudinal axis in the expanded to produce a force directed radially outwardly and to support the alignment component on the patient's heart, vasculature and/or implant.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A method for preparing a biodegradable tissue includes providing one or more native biological tissue(s) or one or more decellularized biological tissue(s). The method includes structurally stabilizing the one or more native biological tissue(s) or the one or more decellularized biological tissue(s) with a tissue water replacement material to obtain a structurally stabilized tissue and providing one or more permeable material layer(s). The method includes placing the structurally stabilized tissue on the one or more permeable material layer(s) or between two of the one or more permeable material layers and drying the structurally stabilized tissue while applying a pressure to the structurally stabilized tissue to obtain a dried biodegradable tissue.
A method for preparing a biological material for a medical application includes exposing the biological material to a first liquid, for example including, by at least 10%, a component other than water, and applying a first compression step onto the biological material, wherein the first compression step includes repeatedly applying a compression force in a plurality of compression intervals. The method further includes drying the biological material, and can included applying second and/or third liquids after respective first and second compression steps.
An implantable covered stent (1), the covered stent (1) being expandable in a radial direction (R) from a collapsed state to an expanded state, wherein the covered stent (1) further comprises: a scaffold (2) comprising an inner side (2a) and an outer side (2b), and a tubular inner stent cover (3) arranged on the inner side (2a) of the scaffold (2), the tubular inner stent cover (3) comprising an inner surface (3a) delimiting a lumen (4) of the covered stent (1), wherein the inner surface (3a) of the inner stent cover (3) is a microstructured surface and/or has a surface roughness Rz in the range of from 1.0 to 5.0 µm.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
An implant includes a base body defining a receptacle configured to receive an X-ray marker in the base body. A plastically deformed X-ray marker is force fit into the receptacle. A flexible film is between the X-ray marker and the based body. The flexible film is arranged such that the X-ray marker does not contact the base-body.
B29C 65/20 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool with direct contact, e.g. using "mirror"
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
B29C 65/00 - Joining of preformed partsApparatus therefor
B29C 65/44 - Joining a heated non-plastics element to a plastics element
A vascular implant, in particular a prosthetic heart valve, for providing valve function, has a stent structure with a proximal conical-convex inflow region, a distal, linear cylindrical outflow region, an intermediate transition region, and a corresponding valve arrangement. When the stent structure is in the expanded state, a higher maximum radial force exists in the inlet region in direct comparison to the lower maximum radial force in the outlet region and in the transition region.
A61F 2/915 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
A packaging arrangement for a medical device includes at least one device recess configured to receive the medical device. A loading is basin configured to receive a liquid that can manipulate the medical device housed in the at least one device recess or to be connected to the medical device housed in the at least one device recess. A spillway basin is connected to the loading basin via a spillway passage having a spillway passage inflow and a spillway passage outflow. The spillway passage includes a downward slope from the spillway passage inflow to the spillway passage outflow configured to promote a liquid flow to the spillway passage outflow.
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
36.
PACKAGING ARRANGEMENT FOR A MEDICAL DEVICE AND CONNECTING ELEMENT FOR SUCH A PACKAGING ARRANGEMENT
A detachable connecting element for a packaging arrangement includes a first connecting element part and a second connecting element part configured for relative movement with respect to each other around a connecting element axis (R) by a rotational or helical movement to transfer the detachable connecting element from a linking state to a non-linking state. The second connecting element part includes at least one protrusion. The first connecting element part includes at least one recess configured to incorporate the at least one protrusion. The at least one protrusion includes at least one curved protrusion sidewall. The at least one recess includes at least one curved recess sidewall. The at least one curved protrusion sidewall or the at least one curved recess sidewall includes a slope.
A catheter system can be selectively combined by a clinical operator to form at least two configurations selected from the group of a dilator configuration, a percutaneous transluminal angioplasty configuration, an LLS (lesion length selective) percutaneous transluminal angioplasty configuration, a CTO-dilator configuration, and a reentry-dilator configuration. A manifold is configured for fluid communication and is insertable into at least one support catheter. A lock-grip handle is configured for the at least two configuration and is configured to coaxially engage and seal with the at least one support catheter and to mechanically actuate the at least two functional components such that distal tips of the at least two functional components can be projected controllably in vivo through the distal end of the at least one support catheter.
A packaging for a medical device includes an outer packaging defining an internal space. A first and a second tray are configured to be arranged in the internal space. The second tray includes at least one protrusion on a bottom side of the second tray. The first tray includes at least one recess on a top side of the first tray in alignment with the protrusion. The second tray is configured to be arranged on the first tray so that the at least one protrusion engages with the at least one recess.
The present invention relates to a stent (1) and a catheter system (2) comprising such a stent (1), the stent (1) comprising: a self-expandable scaffold (10) extending along an axial direction (x) comprising a plurality of open cells (11) formed by a plurality of circumferential strut structures (12) connected by axial struts (13) extending along the axial direction (x), the scaffold (10) comprising an outside facing away from an interior (14) of the stent (1) surrounded by the scaffold (10), the interior (14) forming a passage for blood through the stent (1) in an implanted state of the stent (1), a proximal end (15) configured to be connected to a catheter (3) to allow returning at least the scaffold (10) into a lumen (30) of the catheter (3), and a cover (16) arranged at least on the outside of the scaffold (10), the cover (16) being further configured to carry a drug to be administered and/or to seal a vascular rupture.
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts
A connector for connecting a medical implant to a delivery catheter includes a proximal portion and a distal portion connected to the proximal portion via a central portion. The proximal, distal and central portions extend along a central axis (A). A distal end of the distal portion facing away from the central portion. At least one recess is formed in the central portion and in the distal portion. The at least one recess is configured to receive a connecting element of the medical implant configured to connect the medical implant to the connector. The distal portion tapers towards the distal end. The distal portion can include a conical section, and an outer surface of the conical section includes a generatrix that encloses an acute angle (α) with the central axis (A), with the acute angle (α) in the range of between 20° and 60°.
Medical apparatus and instruments for treating
cardiovascular diseases, medical devices for treating or
diagnosing cardiovascular diseases, medical implants made of
artificial materials, in particular for anchoring joint
capsule components and ligament and tendon structures,
catheters, medical and surgical catheters, intracardiac
catheters, catheters for treating heart and cardiovascular
diseases, medical balloons, medical balloons for
angioplasty, medical stents, balloon catheters, coatings
sold as integral components of medical stents, balloons and
other implantable medical devices.
A preferred embodiment folding box includes a bottom. A circumferential lateral wall is connected to the bottom. A lid is hinged to the rear wall portion, so that the lid is pivotable in an open state of the folding box and closed state. A panel of the wall includes two front flaps each being connected to the panel via a first crease. In the closed state of the folding box, a slot is delimited by a front wall portion, an edge region and the two front flaps. A slot is arranged between the edge region and the front wall portion in the closed state to allow insertion of a package information leaflet. The wing is integrally connected to the front wall portion via a second crease and configured to protrude from the front wall portion along the panel of the lid when the folding box is in the closed state.
A catheter includes a rolling membrane defining an inner volume that can be pressurized. The rolling membrane is configured to roll out in a longitudinal direction (D) into a rolled-out state. An inner shaft is attached to the rolling membrane. The membrane can roll out in a longitudinal direction along a vessel of a patient.
A method for embedding a balloon, arranged on a catheter, in an implant having an open-work structure consists of: producing an assembly consisting of the catheter with the balloon and the implant mounted on the outer side of the balloon, inserting the assembly into a cavity of an embedding mold, which is lined on its inner wall with a protective film, wherein the protective film is strip-like, and a width of the protective film is greater than the circumference of the cavity, connecting the catheter to a fluid source, heating the embedding mold with the assembly in a heating element for a predefined time, applying internal pressure to the balloon by the fluid source, cooling the embedding mold with the assembly with a predefined second internal pressure in the balloon, deflating the balloon after cooling the embedding mold with the assembly, and removing the from the mold.
Medical apparatus and instruments for treating cardiovascular diseases; medical devices for treating or diagnosing cardiovascular diseases; medical implants made of artificial materials, in particular for anchoring joint capsule components and ligament and tendon structures; catheters; medical and surgical catheters; intracardiac catheters; catheters for treating heart and cardiovascular diseases; medical balloons; medical balloons for angioplasty; medical stents; balloon catheters; coatings sold as integral components of medical stents; medical balloons and other implantable medical devices for treating or diagnosing cardiovascular diseases, for anchoring joint capsule components and ligaments and tendon structures, and for treating or diagnosing vascular diseases
A computer-implemented method and system for virtual vascular intervention applies a machine learning algorithm (A1) to a pre-acquired first data set (DS1) of medical image data of a patient (P) and a second data set (DS2) of patient medical parameters and/or natural language data related to a medical condition of the patient (P) to identify at least one pathological feature. The identified at least one pathological feature is indicated in a three-dimensional virtual model (M) of at least one portion of the body of the patient (P). A virtual vascular intervention is executed using the generated three-dimensional virtual model (M) and at least one surgical tool. Haptic feedback (F) is provided to a user using operational data of the virtual vascular intervention.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
47.
CATHETER COMPRISING A ROLLING MEMBRANE AND A TRANSDUCER
The present application relates to rolling membrane catheter comprising at least one transducer (e.g. a pressure wave generator). The application is further related to a method for treating calcified lesions in blood vessels using such a catheter.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
The present invention, inter alia, relates to a catheter, comprising a rolling membrane and a method for crossing a stenosis or a chronic total occlusion using a rolling membrane catheter.
A computer implemented method for classifying or suggesting at least one medical device and/or at least one drug clinically associated with a first data set (DS1) of medical parameters of a patient, The method includes providing (S1) the first data set (DS1), applying (S2) a machine learning algorithm (A1) and/or a rule-based algorithm (A2) to the first data set (DS1), and outputting (S3) a second data set (DS2) including at least one class (C) representing the at least one medical device and/or the at least one drug clinically associated with the first data set (DS1) The invention further relates to a corresponding system and training method.
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A method for producing a magnesium alloy having improved mechanical and electrochemical properties. The method includes vacuum distilling magnesium to produce a purified magnesium starting material. The magnesium starting material is melted with aluminum and zinc to generate a billet of the alloy, the billet having 2.0 to 10.0% by weight Al and 0.25% to 4.0% by weight Zn, the remainder being magnesium containing impurities in a total amount of no more than 0.0063% by weight of Fe, Si, Mn, Co, Ni, Cu, Zr, Y, Sc or rare earths having the ordinal numbers 21, 57 to 71 and 89 to 103, Be, Cd, In, Sn and/or Pb as well as P, wherein a matrix of the alloy includes intermetallic phases formed of Mg and Al. The alloy is homogenized by annealing at a temperature between 150° C. and 450° C. The homogenized allow is formed in the temperature range between 200° C. and 400° C.
C22F 1/06 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of magnesium or alloys based thereon
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
The invention refers to an apparatus for laser welding of an inner workpiece (21, 121, 221, 321, 421) to an outer workpiece (22, 122, 222, 322, 422) of a medical device, for example a catheter, at a welding area, the inner workpiece (21, 121, 221, 321, 421) and the outer workpiece (22, 122, 222, 322, 422) having a longitudinal axis (25), wherein the apparatus comprises a bearing device (10) comprising a bearing element (11, 111), wherein the bearing element (11, 111) is configured to apply pressure onto the outer workpiece (22, 122, 222, 322, 422). Further, the apparatus comprises a laser device (5) emitting electromagnetic radiation for welding, wherein the laser device is configured such that the emitted electromagnetic radiation is transmitted through the bearing element (11, 111) to the welding area.
B29C 65/24 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool characterised by the means for heating the tool
A crossing catheter system for crossing chronic total occlusion includes or consists of a support catheter having a support catheter shaft defining a support catheter lumen capable of receiving a dilator. A dilator is arranged within the support catheter lumen. A locking handle is arranged at a proximal support catheter end. The dilator has a proximal segment with a uniform radial circumference and a distal segment that has a radial circumference that is smaller than the radial circumference of the proximal segment.
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
53.
FABRICATION OF THREE-DIMENSIONAL COMPONENTS FROM BACTERIAL CELLULOSE
The present invention relates to a method for generating a three-dimensional component from bacterial cellulose, comprising the steps of: providing a support structure (2) comprising an outer surface (2a), the support structure (2) allowing passage of oxygen therethrough as well as through the outer surface (2a), providing a layer (3) arranged on said outer surface (2a) of the support structure (2), the layer (3) being permeable to oxygen, immersing the support structure (2) and the layer (3) arranged thereon at least partially in a nutrient solution (4) comprising bacteria capable of forming bacterial cellulose in the presence of oxygen, and passing oxygen into the support structure (2) so that oxygen permeates through the layer (3) allowing bacteria in the nutrient solution to form a component that is comprised of bacterial cellulose and is arranged on an outer surface (3a) of the layer (3).
C12P 19/04 - Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
D04H 1/76 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres otherwise than in a plane, e.g. in a tubular way
54.
BALLOON FOR A BALLOON CATHETER, IN PARTICULAR A SCORING BALLOON CATHETER
The invention relates to a balloon (1) for a balloon catheter, in particular a scoring balloon catheter, having a plurality of inflatable and expandable balloon sections (10), which are arranged next to one another in an axial direction (x) of the balloon (1), wherein two adjacent balloon sections (10) are connected to one another via a shaft segment (11), wherein the shaft segment (11) forms a constriction between the balloon sections (10) in an inflated state of the balloon (1), which constriction in the inflated state of the balloon (1) has a smaller external diameter than the balloon sections, and at least one scoring structure (2) which is arranged on the balloon (1) and can be expanded together with the balloon (1) and has longitudinally extending sections (20) running in the axial direction (x). Furthermore, the invention relates to balloon catheter having such a balloon.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A catheter system includes an outer catheter having an outer catheter shaft defining an outer catheter lumen. At least one inner member is arranged within the lumen. The at least one inner member is relatively movable to the outer catheter in an unrestricted moving state. An axial movement restriction device includes an actuation mechanism and a locking mechanism. The axial movement restriction device can restrict an axial movement of the at least one inner member in a restricted moving state compared to the axial movement in the unrestricted moving state.
A label plate for a catheter connector includes a label plate body configured to be mounted around (and can be fixed onto) an outer shell surface of the catheter connector. A shape of an inner surface of at least a segment of the label plate body corresponds to the shape of an outer surface of at least a section of the catheter connector.
A prosthetic heart valve includes a stent structure configured to expand from a compressed state for transluminal delivery to a natural expanded state and having an overall height (H). The stent structure includes a mesh structure that has an essentially tubular shape and defines a circumference with contours, wherein the contours define a proximal inlet region and a distal outlet region. The proximal inlet region and the distal outlet region are directly connected to one another. The mesh structure includes a plurality of closed cells that in a longitudinal direction of the prosthetic heart valve have varying cell sizes and cell configurations to form a plurality of cell patterns that vary in size between the proximal inlet region and the distal outlet region. A valve is arranged inside a lumen of the stent structure. The overall height (H) of the stent structure is less than 45 mm.
An implant having at least one biodegradable support structure and at least one dried covering material at least partially covering the at least one biodegradable support structure. The dried covering material is selected from an autologous, xenogeneic or allogeneic material or combinations thereof. The biodegradable support structure includes or consists of magnesium, zinc or iron; or the biodegradable support structure includes or consists of a biodegradable magnesium-based alloy, a biodegradable zinc-based alloy or a biodegradable an iron-based alloy.
A balloon catheter (1), comprising a shank (2) extending in an axial direction (x) and connected at a distal end to an inflatable balloon (3) surrounding a balloon interior (30), wherein the balloon interior (30) can be pressurised with a fluid medium via a lumen of the shank (2) to inflate the balloon (3), characterized in that the balloon catheter (1) comprises a vibration exciter (4) arranged at least partially in the balloon interior (30), which vibration exciter is configured to set the balloon (3) to vibrate in a radial direction (R) extending perpendicular to the axial direction (x).
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A beam block for laser cutting to produce a perforated tubular workpiece includes a tubular head section configured to be accommodated within an inner cavity of a semi-finished product during laser cutting, The tubular head section includes a recess at its first end configured to accept molten workpiece material into an inner surface of the tubular head section. A shaft section is located at a second end of the tubular head section. A plunger is configured to be reciprocated along an inner cavity of the tubular head section inner to the first end of the tubular head section to thereby eject molten workpiece material from the inner surface of the tubular head section. The plunger can be reciprocated periodically during laser cutting to eject molten workpiece material.
An x-ray marker is formed by detaching the x-ray marker from a material layer by severing at a predetermined breaking point. A contact face of the breaking point between two adjacent edge portions lies farther inward into the x-ray marker than the edge portions between which the breaking point is disposed. There is also described a semifinished product and a medical implant with an x-ray marker.
A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
B23P 15/00 - Making specific metal objects by operations not covered by a single other subclass or a group in this subclass
A sealing device (1) for a medical device, the sealing device (1) comprising: an annular outer support member (2) with inner surface (2a), a deformable annular sealing member (3) comprising an outer surface (3a), the a support member (2) arranged over the sealing member (3) so that the inner surface (2a) of the annular outer support member (2) faces the outer surface (3a) of the deformable annular sealing member (3), and a body (4) of a shape memory alloy, the body surrounded by the deformable annular sealing member (3), wherein the body (4) extends along an axial direction (x) and is configured to assume an expanded state at a first temperature and a contracted state at a higher second temperature, wherein the body (4) is contracted in the axial direction (x) in the contracted state causing the deformable annular sealing member (3) to expand in a radial direction (R).
A rolling membrane catheter may be provided, comprising a first rolling membrane. The rolling membrane catheter may further comprise a motion unit for determining a motion state of the first rolling membrane. The rolling membrane catheter may be adapted for coupling with a fluid unit for determining a fluid pressure and/or a fluid flow of the first rolling membrane. The rolling membrane catheter may further be adapted such that as to automatically couple the fluid unit and the motion unit for synchronized operation at least in part based on the motion state, the fluid pressure, and/or the fluid flow.
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
64.
OPTIMIZED DESIGN OF A ROLLING MEMBRANE AND A CATHETER OF A ROLLING MEMBRANE CATHETER
The present invention relates to rolling membrane catheters and methods for making a rolling membrane catheter. Also a method for connecting an inner shaft and an outer shaft to a rolling membrane is described. The rolling membrane may comprise an atraumatic tip forming a distal tip of the catheter when the rolling membrane is in a rolled-in state.
A balloon catheter system has a catheter with a catheter shaft surrounding a lumen. A balloon is connected to a distal end of the catheter shaft such that a fluid inflation medium can be introduced into or removed from a balloon interior via the lumen. A pressure sensor is configured to measure an instantaneous pressure (p) of the inflation medium in the lumen during inflation and/or deflation of the balloon. A flow sensor is configured to measure an instantaneous volume flow (v) of the inflation medium during the inflation and/or deflation. An evaluation unit is configured to record the instantaneous pressure and the instantaneous volume flow and to determine therefrom a time curve of the flow resistance (R).
A catheter comprises a rolling membrane and at least one locking means configured to lock a motion of the rolling membrane at least in part based on a fluid state of the catheter.
The present invention, inter alia, relates to a guide extension catheter comprising a rolling membrane, an inner shaft, wherein a first portion of the rolling membrane is connected to the inner shaft and wherein the catheter further comprises a connection element for temporarily connecting a second portion of the rolling membrane to an outer shaft.
A catheter system may be provided, wherein the catheter system may comprise a rolling membrane guiding catheter and a docking unit. The docking unit may be provided for automatically inserting a plurality of devices into the rolling membrane guiding catheter.
The invention is directed to a method to produce hollow cylinders and further relates to a hollow cylinder manufactured by this process, in particular a hollow cylinder based on a magnesium alloy, and an apparatus for carrying out the process.
B21C 1/00 - Manufacture of metal sheets, wire, rods, tubes or like semi-manufactured products by drawing
B21C 1/24 - Metal drawing by machines or apparatus in which the drawing action is effected by means other than drums, e.g. by a longitudinally-moved carriage pulling or pushing the work or stock for making metal sheets, rods or tubes specially adapted for making tubular articles by means of mandrels
B21C 1/34 - Guiding or supporting the material or mandrels
The invention relates to an apparatus for producing a hollow cylinder for medical technology or for a medical product, and a process using said apparatus and a hollow cylinder manufactured by this process, in particular based on a magnesium alloy.
The present invention, inter alia, relates to a computer-implemented method for training an artificial intelligence (AI) engine for classifying a stent, comprising: providing a plurality of AI engine training data sets, wherein each AI engine training data set comprises a training image data set associated with a stent and label data associated with the training image data set, wherein the label data indicates at least one of a plurality of predetermined classes, assigning, by the AI engine, at least one of the plurality of predetermined classes to each training image data set and adjusting the AI engine based at least in part on a comparison, for each of the plurality of AI engine training data sets, of the at least one class assigned to the training image data set of the AI engine training data set with the label data of the AI engine training data set.
inter aliainter alia, relates to a device for monitoring a health risk for a patient. The device (400) comprises means (410), such as a smartphone camera, for obtaining visual information (430), such as a video sequence, associated with a skin (420) of the patient and means (430), such as a cloud-based trained Al engine, for detecting an anomaly on the skin of the patient based at least in part on the obtained visual information as well as means (440) for assigning a scoring value (445) to the detected anomaly, wherein the scoring value is associated with the health risk for the patient. The scoring value may help to diagnose or predict peripheral vascular diseases.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
73.
CATHETER DEVICE FOR DELIVERING A MEDICAL IMPLANT ALLOWING RESHEATHING OF THE IMPLANT
A catheter device for implanting a medical implant such as a prosthetic heart valve has a handle configured to control/steer multiple sheaths of the catheter device. A handle includes a grip portion, a rotatable deployment knob and a traveler. An outer sheath is connected to the traveler and the deployment knob is operatively connected to the traveler such that the traveler and thereby the outer sheath are moved along the longitudinal axis with respect to the inner sheath. The handle includes a rotatable axial positioning knob and a rotatable deflection knob. The deployment knob is arranged proximally to the axial positioning knob.
A production system for producing a medical device from a tube includes a tube positioning device for positioning the tube. The tube positioning device is configured to hold the tube such that a portion of the tube extends from the tube positioning device along a longitudinal direction. A guiding device is used to guide the portion of the tube, and a laser cutting device is used to form the medical device from the portion of the tube. The guiding device comprises a plurality of bearing elements each configured to abut the portion of the tube and each having a convex curvature in a plane spanned by the longitudinal direction and a transverse direction perpendicular to the longitudinal direction.
A method for producing a swellable body including bacterial cellulose includes providing a body made of bacterial cellulose, cleaning the body using at least one liquid medium, freezing the body at atmospheric pressure for at least six hours, freeze drying the body, and mechanically pressing the entire molded body or parts thereof after freeze drying of the body. A body of bacterial cellulose is improved regarding its swelling capability. A swelling factor of at least 1000% is provided by the body of bacetrial cellulose
The present invention relates to an instruction manual (1) for an implantable medical device, comprising at least a first page (10) having a front side (10a) and a back side (10b), wherein the first page (10) comprises an integrated patient implant (20) card releasably connected (eg via an elongated perforation (21) or by an adhesive) to an adjacent portion (10c) of the first page (10). A fold line (23) is provided. A slit (22) can be part of the perforation. The first page can be the cover of a book.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
B42D 15/04 - Foldable or multi-part cards or sheets
B42D 3/12 - Book covers combined with other articles
77.
SYNTHESIS AND CHARACTERIZATION OF CYCLIC HYDROCARBON ESTERS OF EVEROLIMUS
This application relates generally to the field of synthesis, formulations and perivascular treatment methods involving cyclic ester derivatives of everolimus.
A61P 7/00 - Drugs for disorders of the blood or the extracellular fluid
A61P 41/00 - Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
78.
MACROCYCLIC TRIENE IMMUNOSUPPRESSIVE COMPOUNDS FOR PERIVASCULAR MEDICAL TREATMENT OF VASCULAR ACCESS FISTULAS, GRAFTS AND OTHER VASCULAR CONDITIONS
This application relates generally to the field of treatment or prevention of "open" vascular surgical interventions with administration of a macrocyclic triene immunosuppressive compound in order to reduce or eliminate stenotic and/or vascular cancer conditions.
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61K 9/00 - Medicinal preparations characterised by special physical form
79.
CATHETER SYSTEM WITH HYDRAULICALLY INFLATABLE STABILIZERS
PTA catheters and improved PTA methods address problems associated with PTA procedures. One or more stabilizers are activated to hold or fix the PTA catheter at a desired relative position within a support catheter. Timely activation of the stabilizers can prevent deformation of the PTA apparatus during manipulation of the PTA apparatus within biological vessels.
This application relates generally to the field of drug treatment paradigms based on specifically formulated compounds for use in targeted therapy or disease prevention. Specifically, this technology provides for compositions and methods for treating, stabilizing, preventing or delaying disease conditions related to viral infections and other inflammatory conditions.
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61K 9/00 - Medicinal preparations characterised by special physical form
An electrolyte for electropolishing metal surfaces, in particular workpieces, in particular made of titanium or titanium alloys such as nitinol. The electrolyte composition includes methanesulfonic acid and more than one polyhydric alcohol. The content of methanesulfonic acid is less than 15 vol %, the polyhydric alcohols having at least one diol and at least one polyalcohol. The at least one diol accounts for 20 to 65 vol %, and the at least one polyalcohol accounts for 20 to 65 vol %
A medical valve implant includes an implant structure fastened to a base body. The base body has cells that extend in a circumferential direction of a valve implant. An end section bulges in a curved shape outwardly in a radial direction of the base body. The end section has a larger diameter than an axially adjacent collar portion of the base body. A collar includes a first cell structure provided to form, in an intended end state, an intended inner cross-section of the base body that is matched to an intended outer cross section of the implant structure. A holding device extends axially from and beyond the cells. The holding device includes a leg directly connected to a terminal end of one of the cells and a head at an opposite end of the leg. One or both of the leg and the head is canted radially inward toward a geometric center of the base body.
A communication device for near field communication (NFC) with a catheter includes an NFC coil and a communication circuit connected thereto and is configured for bidirectional near-field communication with the catheter. The device includes a rechargeable energy storage device, and an electric charging coil connected to a charging circuit for charging the energy storage device. A housing surrounds the NFC coil, the communication circuit, the energy storage device, the charging coil and the charging circuit. The housing is configured to be releasably secured to the catheter for near-field communication with the catheter. The housing is preferably in the form of a catheter handle. A system includes a docking station configured to communicate with and dock the communication device. The system can include a computer configured to communicate with the docking station.
The invention relates to a catheter, comprising an outer shaft and an inner shaft, wherein the inner shaft is at least partially arranged within the outer shaft. The catheter further comprises an inflatable element comprising an inflatable volume around an inner lumen. The inflatable element comprises at least two proximal ends connected to the inner shaft and at least one distal end connected to the outer shaft.
42 - Scientific, technological and industrial services, research and design
Goods & Services
Reabsorbable and absorbable parts and components of medical
devices and implants, namely metals, chemical compounds of
metals and metal alloys. Conducting medical and clinical research and development in
the field of coronary heart disease and peripheral arterial
diseases; conducting clinical studies and trials to assess
and evaluate the performance, safety and efficiency of
medical devices.
The present invention relates to a method for joining at least a first and a second component (10, 11) of a catheter using a clamping tool (3) and heat treatment, without the use of heat shrink tubing. Furthermore, a device (1) for joining at least two catheter components (10, 11) of a catheter is described, comprising or consisting of: a clamping tool (20), a heating device (3), and optionally a cooling device. A (heat shrink tubing-free) catheter or catheter part, preferably a guide wire exit port, is disclosed, which has been obtained by joining of at least two catheter components of the catheter by using said device or said method.
B29C 65/00 - Joining of preformed partsApparatus therefor
B29C 35/08 - Heating or curing, e.g. crosslinking or vulcanising by wave energy or particle radiation
B29C 65/02 - Joining of preformed partsApparatus therefor by heating, with or without pressure
B29C 65/36 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated elements which remain in the joint, e.g. "verlorenes Schweisselement" heated by induction
87.
AXIALLY MOVABLE AND PRESSURE-TIGHT CONNECTION OF VI CATHETER SHAFTS
Catheter which comprises an inner shaft (2) and an outer shaft (1), wherein the inner shaft comprises a distal inner shaft portion and a portion arranged proximally to the distal inner shaft portion. The catheter further comprises a proximal rolling membrane (3) which is attached to the inner shaft and to the outer shaft, wherein the proximal rolling membrane is attached to the portion arranged proximally to the distal inner shaft portion.
A digital prioritizing admission/treatment system and corresponding devices and methods are disclosed. The prioritizing admission/treatment system, devices and methods are based on an urgency rating of a treatment of a patient. The urgency rating may be determined using an artificial intelligence model. A corresponding training method of the artificial intelligence is disclosed as well.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
89.
DILATOR TIP DESIGN FOR ENHANCED FORCE TRANSMISSION
A dilator comprises: a shaft (110, 210) and a reinforcing element (120, 220) comprising a generally cylindrical face. The reinforcing element (120, 220) is connected to a distal end of the shaft (110, 210).
A catheter device for implanting a medical implant has a handle that includes a locking element configured to be moved from a first to a second state. The locking element limits a movement of a traveler and therewith of a capsule in a distal direction (D) in the first state. The locking element allows further movement of the traveler and therewith of the capsule in the distal direction in the second state.
A method for producing a tubular semi-finished product for an implant scaffold which leads to an improvement of the dilatability of the scaffold. The semi-finished product consists of a magnesium alloy. The method includes extruding a tubular semi-finished product by a heated die or tempering an extruded tubular semi-finished product by a heating device. A tube drawing device applies a tensile stress and/or a torsional stress. The tube drawing device has a clamping device. The clamping device is fixed on a predefined portion of the tubular semi-finished product. Tensile force generated by the tube drawing device and/or the torsion moment generated by the tube drawing device is transferred to the semi-finished product.
A delivery system includes an interventional device having a distal end portion and an introducer configured to insert the interventional device into a vessel of a patient. The introducer has a tubular sheath configured to be inserted into the vessel defining a lumen to guide the interventional device into the vessel. The introducer includes a fastening mechanism configured to releasably fasten the introducer to the interventional device to prevent movement of the introducer with respect to the interventional device along a longitudinal axis.
A catheter system (1, 1') for a interventional procedure, within a patient's heart, vasculature and/or an implant (42) fixed at the patient's heart or vasculature (50, 51, 52) comprising a bendable and/or steerable extension arm (12) and a guiding sheath (10) with a distal section is described which allows for precise and efficient location of a paravalvular leakage and deployment of an occluding member. The extension arm is fixed at the distal end of the distal section of the guiding sheath or is configured to be moved along the guiding sheath so that it projects in an operation position from the distal end of the distal section, wherein the extension arm has an inner lumen through which a guidewire (17) can be maneuvered and defines a longitudinal axis (15), wherein the catheter system further comprises at least one alignment component (20, 120, 220, 320, 420, 520) having a collapsed state and being configured to expand into an expanded state, wherein the alignment component is attached to the guiding sheath at a pre-defined position within the distal section but proximally from its distal end or the alignment component is configured to be advanced along the guiding sheath to this pre-defined position within the distal section, wherein the alignment component comprises a plurality of struts (21, 28) distributed on the circumference, wherein each strut of the plurality of struts runs at least sectionwise into radial direction and/or inclined with regard to the longitudinal axis in the expanded state thereby producing a force directed radially outwardly and supporting the alignment component on the patient's heart, vasculature and/or implant. Further, a method for the closure of at least one paravalvular leakage (53) is explained.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
94.
SYSTEM AND DEVICE FOR REDUCTION OF VARICOSE VEIN DIAMETER
The present invention relates to an implant delivery system (1) for implanting an implant (10) for reducing a luminal diameter of a vessel, comprising: an implant (10) being configured to be anchored to an inner wall (W) of the vessel (V) and to contract so as to reduce the luminal diameter (D) of the vessel (V), and a catheter (2) comprising a catheter sheath (20) and an expansion device (21) for expanding and deploying the implant (10) at an implantation side in the vessel (V).
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A vascular support implant is formed from a magnesium alloy. The alloy includes Zn and/or one of the following elements: Ca, Sr. The Zn content is ≤1.5 wt. % and a Ca content is ≥0.25 wt. %.
The invention relates to a guiding catheter (1) comprising an outer shaft (2) defining a first guiding lumen (20) in an interior of the outer shaft (2); an inner shaft (3) movably arranged at least partially in the first guiding lumen (20), wherein the inner shaft (3) defines a second guiding lumen (30) in an interior of the inner shaft (3); and a dividing device (4) arranged in a proximal end region of the guiding catheter (1), the dividing device (4) having a first port (41) and a second port (42) angularly arranged to each other, wherein both the first port (41) and the second port (42) provide access to the first guiding lumen (20). According to an aspect of the invention, the inner shaft (3) extends through the second port (42) into the first guiding lumen (20), wherein the inner shaft (3) comprises at least section-wise a slit (32) along a longitudinal extension direction (F) of the inner shaft (3), wherein the slit (32) provides access to the second guiding lumen (30) and enables a working catheter (5) to enter the second guiding lumen (30) from the first guiding lumen (20).
A process for chemical crosslinking of tissue joining partners including crosslinkable groups, such as free amino groups, by a suitable crosslinking agent under static, quasi-static or periodic pulsatile pressure compression. The compression can be in a defined overlap region for seamless, dense and tight tissue closure. This results in a seamless, homogeneous, and at the same time mechanically stable connection/joining of tissue/tissue components. Seamless connected tissue is provided that includes a piece of tissue having at least two tissue parts overlapping each other and the at least two tissue parts overlapping each other that are materially bonded to each other via crosslinked groups of the tissue.
A process for three-dimensional shaping of a biological and/or artificial tissue/tissue component. The process is consistent for shaping tissues and can produce a desired three-dimensional and permanent shaping of the tissue/tissue component via crosslinking. A suitable crosslinking agent is used in combination with shaped body and a granulate.
A method for chemically crosslinking and optionally shaping (including thickness reduction) substantially non-cross-linked tissue, in particular biological tissue, using a permeable material layer. The method can be used in combination with a stepless pressure load/compression on the tissue, so as to always allow fluid transport into and out of the tissue to be treated under the chemical cross-linking; along the lines of drainage. The method can be carried out under different pressure loads/compressions, in particular in order to specifically influence the resulting tissue properties, and, for example, to bring about a homogeneous thickness distribution of the tissue and/or to deliberately and specifically place inhomogeneities, if desired. Furthermore, the method allows the introduction/imprinting of a consistent three-dimensional shape into the tissue to be treated, e.g. of inhomogeneities in the thickness of the tissue.
The present invention relates to use of a UV-sensitive copolymer and a hydrophilic coating containing the copolymer, for coating a surface of a vascular medical product. The UV-sensitive copolymer comprises repeating units of (a) vinylpyrrolidone, and (b) perfluorophenylazide, wherein the copolymer has a statistical distribution of the repeating units (a) and (b) and has a molecular weight of 5,000 to 50,000 g/mol. The invention further relates to a method for coating a surface of a vascular medical product, and the coated vascular medical products obtained.
