A preferred embodiment folding box includes a bottom. A circumferential lateral wall is connected to the bottom. A lid is hinged to the rear wall portion, so that the lid is pivotable in an open state of the folding box and closed state. A panel of the wall includes two front flaps each being connected to the panel via a first crease. In the closed state of the folding box, a slot is delimited by a front wall portion, an edge region and the two front flaps. A slot is arranged between the edge region and the front wall portion in the closed state to allow insertion of a package information leaflet. The wing is integrally connected to the front wall portion via a second crease and configured to protrude from the front wall portion along the panel of the lid when the folding box is in the closed state.
A catheter includes a rolling membrane defining an inner volume that can be pressurized. The rolling membrane is configured to roll out in a longitudinal direction (D) into a rolled-out state. An inner shaft is attached to the rolling membrane. The membrane can roll out in a longitudinal direction along a vessel of a patient.
A method for embedding a balloon, arranged on a catheter, in an implant having an open-work structure consists of: producing an assembly consisting of the catheter with the balloon and the implant mounted on the outer side of the balloon, inserting the assembly into a cavity of an embedding mold, which is lined on its inner wall with a protective film, wherein the protective film is strip-like, and a width of the protective film is greater than the circumference of the cavity, connecting the catheter to a fluid source, heating the embedding mold with the assembly in a heating element for a predefined time, applying internal pressure to the balloon by the fluid source, cooling the embedding mold with the assembly with a predefined second internal pressure in the balloon, deflating the balloon after cooling the embedding mold with the assembly, and removing the from the mold.
A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
B29C 65/02 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage
A computer-implemented method and system for virtual vascular intervention applies a machine learning algorithm (A1) to a pre-acquired first data set (DS1) of medical image data of a patient (P) and a second data set (DS2) of patient medical parameters and/or natural language data related to a medical condition of the patient (P) to identify at least one pathological feature. The identified at least one pathological feature is indicated in a three-dimensional virtual model (M) of at least one portion of the body of the patient (P). A virtual vascular intervention is executed using the generated three-dimensional virtual model (M) and at least one surgical tool. Haptic feedback (F) is provided to a user using operational data of the virtual vascular intervention.
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
5.
CATHETER COMPRISING A ROLLING MEMBRANE AND A TRANSDUCER
The present application relates to rolling membrane catheter comprising at least one transducer (e.g. a pressure wave generator). The application is further related to a method for treating calcified lesions in blood vessels using such a catheter.
A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes
The present invention, inter alia, relates to a catheter, comprising a rolling membrane and a method for crossing a stenosis or a chronic total occlusion using a rolling membrane catheter.
A computer implemented method for classifying or suggesting at least one medical device and/or at least one drug clinically associated with a first data set (DS1) of medical parameters of a patient, The method includes providing (S1) the first data set (DS1), applying (S2) a machine learning algorithm (A1) and/or a rule-based algorithm (A2) to the first data set (DS1), and outputting (S3) a second data set (DS2) including at least one class (C) representing the at least one medical device and/or the at least one drug clinically associated with the first data set (DS1) The invention further relates to a corresponding system and training method.
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
The invention refers to an apparatus for laser welding of an inner workpiece (21, 121, 221, 321, 421) to an outer workpiece (22, 122, 222, 322, 422) of a medical device, for example a catheter, at a welding area, the inner workpiece (21, 121, 221, 321, 421) and the outer workpiece (22, 122, 222, 322, 422) having a longitudinal axis (25), wherein the apparatus comprises a bearing device (10) comprising a bearing element (11, 111), wherein the bearing element (11, 111) is configured to apply pressure onto the outer workpiece (22, 122, 222, 322, 422). Further, the apparatus comprises a laser device (5) emitting electromagnetic radiation for welding, wherein the laser device is configured such that the emitted electromagnetic radiation is transmitted through the bearing element (11, 111) to the welding area.
B29C 65/24 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage avec un outil chauffé caractérisé par les moyens pour chauffer l'outil
A crossing catheter system for crossing chronic total occlusion includes or consists of a support catheter having a support catheter shaft defining a support catheter lumen capable of receiving a dilator. A dilator is arranged within the support catheter lumen. A locking handle is arranged at a proximal support catheter end. The dilator has a proximal segment with a uniform radial circumference and a distal segment that has a radial circumference that is smaller than the radial circumference of the proximal segment.
A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
10.
FABRICATION OF THREE-DIMENSIONAL COMPONENTS FROM BACTERIAL CELLULOSE
The present invention relates to a method for generating a three-dimensional component from bacterial cellulose, comprising the steps of: providing a support structure (2) comprising an outer surface (2a), the support structure (2) allowing passage of oxygen therethrough as well as through the outer surface (2a), providing a layer (3) arranged on said outer surface (2a) of the support structure (2), the layer (3) being permeable to oxygen, immersing the support structure (2) and the layer (3) arranged thereon at least partially in a nutrient solution (4) comprising bacteria capable of forming bacterial cellulose in the presence of oxygen, and passing oxygen into the support structure (2) so that oxygen permeates through the layer (3) allowing bacteria in the nutrient solution to form a component that is comprised of bacterial cellulose and is arranged on an outer surface (3a) of the layer (3).
C12P 19/04 - Polysaccharides, c.-à-d. composés contenant plus de cinq radicaux saccharide reliés entre eux par des liaisons glucosidiques
D04H 1/76 - Non-tissés formés uniquement ou principalement de fibres coupées ou autres fibres similaires relativement courtes caractérisés par la méthode de formation des voiles ou couches, p. ex. par la réorientation des fibres autrement que dans un plan, p. ex. de manière tubulaire
11.
BALLOON FOR A BALLOON CATHETER, IN PARTICULAR A SCORING BALLOON CATHETER
The invention relates to a balloon (1) for a balloon catheter, in particular a scoring balloon catheter, having a plurality of inflatable and expandable balloon sections (10), which are arranged next to one another in an axial direction (x) of the balloon (1), wherein two adjacent balloon sections (10) are connected to one another via a shaft segment (11), wherein the shaft segment (11) forms a constriction between the balloon sections (10) in an inflated state of the balloon (1), which constriction in the inflated state of the balloon (1) has a smaller external diameter than the balloon sections, and at least one scoring structure (2) which is arranged on the balloon (1) and can be expanded together with the balloon (1) and has longitudinally extending sections (20) running in the axial direction (x). Furthermore, the invention relates to balloon catheter having such a balloon.
A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
A catheter system includes an outer catheter having an outer catheter shaft defining an outer catheter lumen. At least one inner member is arranged within the lumen. The at least one inner member is relatively movable to the outer catheter in an unrestricted moving state. An axial movement restriction device includes an actuation mechanism and a locking mechanism. The axial movement restriction device can restrict an axial movement of the at least one inner member in a restricted moving state compared to the axial movement in the unrestricted moving state.
A label plate for a catheter connector includes a label plate body configured to be mounted around (and can be fixed onto) an outer shell surface of the catheter connector. A shape of an inner surface of at least a segment of the label plate body corresponds to the shape of an outer surface of at least a section of the catheter connector.
A prosthetic heart valve includes a stent structure configured to expand from a compressed state for transluminal delivery to a natural expanded state and having an overall height (H). The stent structure includes a mesh structure that has an essentially tubular shape and defines a circumference with contours, wherein the contours define a proximal inlet region and a distal outlet region. The proximal inlet region and the distal outlet region are directly connected to one another. The mesh structure includes a plurality of closed cells that in a longitudinal direction of the prosthetic heart valve have varying cell sizes and cell configurations to form a plurality of cell patterns that vary in size between the proximal inlet region and the distal outlet region. A valve is arranged inside a lumen of the stent structure. The overall height (H) of the stent structure is less than 45 mm.
An implant having at least one biodegradable support structure and at least one dried covering material at least partially covering the at least one biodegradable support structure. The dried covering material is selected from an autologous, xenogeneic or allogeneic material or combinations thereof. The biodegradable support structure includes or consists of magnesium, zinc or iron; or the biodegradable support structure includes or consists of a biodegradable magnesium-based alloy, a biodegradable zinc-based alloy or a biodegradable an iron-based alloy.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A balloon catheter (1), comprising a shank (2) extending in an axial direction (x) and connected at a distal end to an inflatable balloon (3) surrounding a balloon interior (30), wherein the balloon interior (30) can be pressurised with a fluid medium via a lumen of the shank (2) to inflate the balloon (3), characterized in that the balloon catheter (1) comprises a vibration exciter (4) arranged at least partially in the balloon interior (30), which vibration exciter is configured to set the balloon (3) to vibrate in a radial direction (R) extending perpendicular to the axial direction (x).
A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
A beam block for laser cutting to produce a perforated tubular workpiece includes a tubular head section configured to be accommodated within an inner cavity of a semi-finished product during laser cutting, The tubular head section includes a recess at its first end configured to accept molten workpiece material into an inner surface of the tubular head section. A shaft section is located at a second end of the tubular head section. A plunger is configured to be reciprocated along an inner cavity of the tubular head section inner to the first end of the tubular head section to thereby eject molten workpiece material from the inner surface of the tubular head section. The plunger can be reciprocated periodically during laser cutting to eject molten workpiece material.
B23K 26/38 - Enlèvement de matière par perçage ou découpage
B23K 26/0622 - Mise en forme du faisceau laser, p. ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser par impulsions de mise en forme
18.
X-RAY MARKERS FOR SCAFFOLDS, SEMIFINISHED PRODUCT, AND MEDICAL IMPLANT
An x-ray marker is formed by detaching the x-ray marker from a material layer by severing at a predetermined breaking point. A contact face of the breaking point between two adjacent edge portions lies farther inward into the x-ray marker than the edge portions between which the breaking point is disposed. There is also described a semifinished product and a medical implant with an x-ray marker.
A61F 2/82 - Dispositifs maintenant le passage ou évitant l’affaissement de structures tubulaires du corps, p. ex. stents
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
B23P 15/00 - Fabrication d'objets déterminés par des opérations non couvertes par une seule autre sous-classe ou un groupe de la présente sous-classe
A sealing device (1) for a medical device, the sealing device (1) comprising: an annular outer support member (2) with inner surface (2a), a deformable annular sealing member (3) comprising an outer surface (3a), the a support member (2) arranged over the sealing member (3) so that the inner surface (2a) of the annular outer support member (2) faces the outer surface (3a) of the deformable annular sealing member (3), and a body (4) of a shape memory alloy, the body surrounded by the deformable annular sealing member (3), wherein the body (4) extends along an axial direction (x) and is configured to assume an expanded state at a first temperature and a contracted state at a higher second temperature, wherein the body (4) is contracted in the axial direction (x) in the contracted state causing the deformable annular sealing member (3) to expand in a radial direction (R).
B29C 65/00 - Assemblage d'éléments préformésAppareils à cet effet
F16J 15/06 - Joints d'étanchéité entre surfaces immobiles entre elles avec garniture solide comprimée entre les surfaces à joindre
F16J 15/08 - Joints d'étanchéité entre surfaces immobiles entre elles avec garniture solide comprimée entre les surfaces à joindre exclusivement par garniture métallique
20.
ROLLING MEMBRANE CATHETER WITH AT LEAST PARTLY AUTOMATED ROLLING MEMBRANE PRESSURE AND GUIDEWIRE RETRACTION
A rolling membrane catheter may be provided, comprising a first rolling membrane. The rolling membrane catheter may further comprise a motion unit for determining a motion state of the first rolling membrane. The rolling membrane catheter may be adapted for coupling with a fluid unit for determining a fluid pressure and/or a fluid flow of the first rolling membrane. The rolling membrane catheter may further be adapted such that as to automatically couple the fluid unit and the motion unit for synchronized operation at least in part based on the motion state, the fluid pressure, and/or the fluid flow.
A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
21.
OPTIMIZED DESIGN OF A ROLLING MEMBRANE AND A CATHETER OF A ROLLING MEMBRANE CATHETER
The present invention relates to rolling membrane catheters and methods for making a rolling membrane catheter. Also a method for connecting an inner shaft and an outer shaft to a rolling membrane is described. The rolling membrane may comprise an atraumatic tip forming a distal tip of the catheter when the rolling membrane is in a rolled-in state.
A balloon catheter system has a catheter with a catheter shaft surrounding a lumen. A balloon is connected to a distal end of the catheter shaft such that a fluid inflation medium can be introduced into or removed from a balloon interior via the lumen. A pressure sensor is configured to measure an instantaneous pressure (p) of the inflation medium in the lumen during inflation and/or deflation of the balloon. A flow sensor is configured to measure an instantaneous volume flow (v) of the inflation medium during the inflation and/or deflation. An evaluation unit is configured to record the instantaneous pressure and the instantaneous volume flow and to determine therefrom a time curve of the flow resistance (R).
A catheter comprises a rolling membrane and at least one locking means configured to lock a motion of the rolling membrane at least in part based on a fluid state of the catheter.
The present invention, inter alia, relates to a guide extension catheter comprising a rolling membrane, an inner shaft, wherein a first portion of the rolling membrane is connected to the inner shaft and wherein the catheter further comprises a connection element for temporarily connecting a second portion of the rolling membrane to an outer shaft.
A catheter system may be provided, wherein the catheter system may comprise a rolling membrane guiding catheter and a docking unit. The docking unit may be provided for automatically inserting a plurality of devices into the rolling membrane guiding catheter.
The invention is directed to a method to produce hollow cylinders and further relates to a hollow cylinder manufactured by this process, in particular a hollow cylinder based on a magnesium alloy, and an apparatus for carrying out the process.
B21C 1/00 - Fabrication des tôles, fils, barres, tubes métalliques ou d'autres produits semi-finis similaires par étirage
B21C 1/24 - Étirage par des machines ou appareils dans lesquels l'effort de traction est produit par des moyens autres que des tambours, p. ex. par chariot mû longitudinalement tirant ou poussant le matériau de façon à former des tôles, des barres ou des tubes métalliques spécialement adaptés à la fabrication d'objets tubulaires au moyen de mandrins
B21C 1/34 - Guidage ou support du matériau ou des mandrins
B21C 3/12 - Supports de filièresFilières rotatives
B21C 3/14 - Supports de filières combinés à des dispositifs de guidage du matériau à étirer, ou à des dispositifs pour le refroidissement, le chauffage ou la lubrification
B21C 23/08 - Fabrication de fils, de barres, de tubes
B21C 23/21 - Presses spécialement adaptées à l'extrusion du métal
The invention relates to an apparatus for producing a hollow cylinder for medical technology or for a medical product, and a process using said apparatus and a hollow cylinder manufactured by this process, in particular based on a magnesium alloy.
The present invention, inter alia, relates to a computer-implemented method for training an artificial intelligence (AI) engine for classifying a stent, comprising: providing a plurality of AI engine training data sets, wherein each AI engine training data set comprises a training image data set associated with a stent and label data associated with the training image data set, wherein the label data indicates at least one of a plurality of predetermined classes, assigning, by the AI engine, at least one of the plurality of predetermined classes to each training image data set and adjusting the AI engine based at least in part on a comparison, for each of the plurality of AI engine training data sets, of the at least one class assigned to the training image data set of the AI engine training data set with the label data of the AI engine training data set.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
inter aliainter alia, relates to a device for monitoring a health risk for a patient. The device (400) comprises means (410), such as a smartphone camera, for obtaining visual information (430), such as a video sequence, associated with a skin (420) of the patient and means (430), such as a cloud-based trained Al engine, for detecting an anomaly on the skin of the patient based at least in part on the obtained visual information as well as means (440) for assigning a scoring value (445) to the detected anomaly, wherein the scoring value is associated with the health risk for the patient. The scoring value may help to diagnose or predict peripheral vascular diseases.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
30.
CATHETER DEVICE FOR DELIVERING A MEDICAL IMPLANT ALLOWING RESHEATHING OF THE IMPLANT
A catheter device for implanting a medical implant such as a prosthetic heart valve has a handle configured to control/steer multiple sheaths of the catheter device. A handle includes a grip portion, a rotatable deployment knob and a traveler. An outer sheath is connected to the traveler and the deployment knob is operatively connected to the traveler such that the traveler and thereby the outer sheath are moved along the longitudinal axis with respect to the inner sheath. The handle includes a rotatable axial positioning knob and a rotatable deflection knob. The deployment knob is arranged proximally to the axial positioning knob.
A method for producing a swellable body including bacterial cellulose includes providing a body made of bacterial cellulose, cleaning the body using at least one liquid medium, freezing the body at atmospheric pressure for at least six hours, freeze drying the body, and mechanically pressing the entire molded body or parts thereof after freeze drying of the body. A body of bacterial cellulose is improved regarding its swelling capability. A swelling factor of at least 1000% is provided by the body of bacetrial cellulose
A production system for producing a medical device from a tube includes a tube positioning device for positioning the tube. The tube positioning device is configured to hold the tube such that a portion of the tube extends from the tube positioning device along a longitudinal direction. A guiding device is used to guide the portion of the tube, and a laser cutting device is used to form the medical device from the portion of the tube. The guiding device comprises a plurality of bearing elements each configured to abut the portion of the tube and each having a convex curvature in a plane spanned by the longitudinal direction and a transverse direction perpendicular to the longitudinal direction.
The present invention relates to an instruction manual (1) for an implantable medical device, comprising at least a first page (10) having a front side (10a) and a back side (10b), wherein the first page (10) comprises an integrated patient implant (20) card releasably connected (eg via an elongated perforation (21) or by an adhesive) to an adjacent portion (10c) of the first page (10). A fold line (23) is provided. A slit (22) can be part of the perforation. The first page can be the cover of a book.
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
B42D 15/04 - Cartes ou feuilles pliables ou en plusieurs parties
B42D 3/12 - Couvre-livres ou liseuses combinées avec d'autres objets
34.
SYNTHESIS AND CHARACTERIZATION OF CYCLIC HYDROCARBON ESTERS OF EVEROLIMUS
This application relates generally to the field of synthesis, formulations and perivascular treatment methods involving cyclic ester derivatives of everolimus.
A61P 7/00 - Médicaments pour le traitement des troubles du sang ou du fluide extracellulaire
A61P 41/00 - Médicaments utilisés en chirurgie, p. ex. adjuvants chirurgicaux pour la prévention des adhérences ou pour le remplacement de l'humeur vitrée
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
35.
MACROCYCLIC TRIENE IMMUNOSUPPRESSIVE COMPOUNDS FOR PERIVASCULAR MEDICAL TREATMENT OF VASCULAR ACCESS FISTULAS, GRAFTS AND OTHER VASCULAR CONDITIONS
This application relates generally to the field of treatment or prevention of "open" vascular surgical interventions with administration of a macrocyclic triene immunosuppressive compound in order to reduce or eliminate stenotic and/or vascular cancer conditions.
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
36.
CATHETER SYSTEM WITH HYDRAULICALLY INFLATABLE STABILIZERS
PTA catheters and improved PTA methods address problems associated with PTA procedures. One or more stabilizers are activated to hold or fix the PTA catheter at a desired relative position within a support catheter. Timely activation of the stabilizers can prevent deformation of the PTA apparatus during manipulation of the PTA apparatus within biological vessels.
This application relates generally to the field of drug treatment paradigms based on specifically formulated compounds for use in targeted therapy or disease prevention. Specifically, this technology provides for compositions and methods for treating, stabilizing, preventing or delaying disease conditions related to viral infections and other inflammatory conditions.
A61K 31/436 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à six chaînons ayant l'oxygène comme hétéro-atome du cycle, p. ex. rapamycine
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
An electrolyte for electropolishing metal surfaces, in particular workpieces, in particular made of titanium or titanium alloys such as nitinol. The electrolyte composition includes methanesulfonic acid and more than one polyhydric alcohol. The content of methanesulfonic acid is less than 15 vol %, the polyhydric alcohols having at least one diol and at least one polyalcohol. The at least one diol accounts for 20 to 65 vol %, and the at least one polyalcohol accounts for 20 to 65 vol %
A medical valve implant includes an implant structure fastened to a base body. The base body has cells that extend in a circumferential direction of a valve implant. An end section bulges in a curved shape outwardly in a radial direction of the base body. The end section has a larger diameter than an axially adjacent collar portion of the base body. A collar includes a first cell structure provided to form, in an intended end state, an intended inner cross-section of the base body that is matched to an intended outer cross section of the implant structure. A holding device extends axially from and beyond the cells. The holding device includes a leg directly connected to a terminal end of one of the cells and a head at an opposite end of the leg. One or both of the leg and the head is canted radially inward toward a geometric center of the base body.
A communication device for near field communication (NFC) with a catheter includes an NFC coil and a communication circuit connected thereto and is configured for bidirectional near-field communication with the catheter. The device includes a rechargeable energy storage device, and an electric charging coil connected to a charging circuit for charging the energy storage device. A housing surrounds the NFC coil, the communication circuit, the energy storage device, the charging coil and the charging circuit. The housing is configured to be releasably secured to the catheter for near-field communication with the catheter. The housing is preferably in the form of a catheter handle. A system includes a docking station configured to communicate with and dock the communication device. The system can include a computer configured to communicate with the docking station.
H04B 5/00 - Systèmes de transmission en champ proche, p. ex. systèmes à transmission capacitive ou inductive
A61M 5/168 - Moyens pour commander l'écoulement des agents vers le corps ou pour doser les agents à introduire dans le corps, p. ex. compteurs de goutte-à-goutte
The invention relates to a catheter, comprising an outer shaft and an inner shaft, wherein the inner shaft is at least partially arranged within the outer shaft. The catheter further comprises an inflatable element comprising an inflatable volume around an inner lumen. The inflatable element comprises at least two proximal ends connected to the inner shaft and at least one distal end connected to the outer shaft.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Reabsorbable and absorbable parts and components of medical
devices and implants, namely metals, chemical compounds of
metals and metal alloys. Conducting medical and clinical research and development in
the field of coronary heart disease and peripheral arterial
diseases; conducting clinical studies and trials to assess
and evaluate the performance, safety and efficiency of
medical devices.
The present invention relates to a method for joining at least a first and a second component (10, 11) of a catheter using a clamping tool (3) and heat treatment, without the use of heat shrink tubing. Furthermore, a device (1) for joining at least two catheter components (10, 11) of a catheter is described, comprising or consisting of: a clamping tool (20), a heating device (3), and optionally a cooling device. A (heat shrink tubing-free) catheter or catheter part, preferably a guide wire exit port, is disclosed, which has been obtained by joining of at least two catheter components of the catheter by using said device or said method.
B29C 65/00 - Assemblage d'éléments préformésAppareils à cet effet
B29C 35/08 - Chauffage ou durcissement, p. ex. réticulation ou vulcanisation utilisant l'énergie ondulatoire ou un rayonnement corpusculaire
B29C 65/02 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage
B29C 65/36 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage avec des éléments chauffés qui restent dans le joint, p. ex. un "élément de soudage perdu" chauffés par induction
44.
AXIALLY MOVABLE AND PRESSURE-TIGHT CONNECTION OF VI CATHETER SHAFTS
Catheter which comprises an inner shaft (2) and an outer shaft (1), wherein the inner shaft comprises a distal inner shaft portion and a portion arranged proximally to the distal inner shaft portion. The catheter further comprises a proximal rolling membrane (3) which is attached to the inner shaft and to the outer shaft, wherein the proximal rolling membrane is attached to the portion arranged proximally to the distal inner shaft portion.
A digital prioritizing admission/treatment system and corresponding devices and methods are disclosed. The prioritizing admission/treatment system, devices and methods are based on an urgency rating of a treatment of a patient. The urgency rating may be determined using an artificial intelligence model. A corresponding training method of the artificial intelligence is disclosed as well.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
46.
DILATOR TIP DESIGN FOR ENHANCED FORCE TRANSMISSION
A dilator comprises: a shaft (110, 210) and a reinforcing element (120, 220) comprising a generally cylindrical face. The reinforcing element (120, 220) is connected to a distal end of the shaft (110, 210).
A method for producing a tubular semi-finished product for an implant scaffold which leads to an improvement of the dilatability of the scaffold. The semi-finished product consists of a magnesium alloy. The method includes extruding a tubular semi-finished product by a heated die or tempering an extruded tubular semi-finished product by a heating device. A tube drawing device applies a tensile stress and/or a torsional stress. The tube drawing device has a clamping device. The clamping device is fixed on a predefined portion of the tubular semi-finished product. Tensile force generated by the tube drawing device and/or the torsion moment generated by the tube drawing device is transferred to the semi-finished product.
A catheter device for implanting a medical implant has a handle that includes a locking element configured to be moved from a first to a second state. The locking element limits a movement of a traveler and therewith of a capsule in a distal direction (D) in the first state. The locking element allows further movement of the traveler and therewith of the capsule in the distal direction in the second state.
A delivery system includes an interventional device having a distal end portion and an introducer configured to insert the interventional device into a vessel of a patient. The introducer has a tubular sheath configured to be inserted into the vessel defining a lumen to guide the interventional device into the vessel. The introducer includes a fastening mechanism configured to releasably fasten the introducer to the interventional device to prevent movement of the introducer with respect to the interventional device along a longitudinal axis.
A catheter system (1, 1') for a interventional procedure, within a patient's heart, vasculature and/or an implant (42) fixed at the patient's heart or vasculature (50, 51, 52) comprising a bendable and/or steerable extension arm (12) and a guiding sheath (10) with a distal section is described which allows for precise and efficient location of a paravalvular leakage and deployment of an occluding member. The extension arm is fixed at the distal end of the distal section of the guiding sheath or is configured to be moved along the guiding sheath so that it projects in an operation position from the distal end of the distal section, wherein the extension arm has an inner lumen through which a guidewire (17) can be maneuvered and defines a longitudinal axis (15), wherein the catheter system further comprises at least one alignment component (20, 120, 220, 320, 420, 520) having a collapsed state and being configured to expand into an expanded state, wherein the alignment component is attached to the guiding sheath at a pre-defined position within the distal section but proximally from its distal end or the alignment component is configured to be advanced along the guiding sheath to this pre-defined position within the distal section, wherein the alignment component comprises a plurality of struts (21, 28) distributed on the circumference, wherein each strut of the plurality of struts runs at least sectionwise into radial direction and/or inclined with regard to the longitudinal axis in the expanded state thereby producing a force directed radially outwardly and supporting the alignment component on the patient's heart, vasculature and/or implant. Further, a method for the closure of at least one paravalvular leakage (53) is explained.
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
51.
SYSTEM AND DEVICE FOR REDUCTION OF VARICOSE VEIN DIAMETER
The present invention relates to an implant delivery system (1) for implanting an implant (10) for reducing a luminal diameter of a vessel, comprising: an implant (10) being configured to be anchored to an inner wall (W) of the vessel (V) and to contract so as to reduce the luminal diameter (D) of the vessel (V), and a catheter (2) comprising a catheter sheath (20) and an expansion device (21) for expanding and deploying the implant (10) at an implantation side in the vessel (V).
A61B 17/04 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour la suture des plaiesSupports ou emballages pour aiguilles ou matériaux de suture
A vascular support implant is formed from a magnesium alloy. The alloy includes Zn and/or one of the following elements: Ca, Sr. The Zn content is ≤1.5 wt. % and a Ca content is ≥0.25 wt. %.
The invention relates to a guiding catheter (1) comprising an outer shaft (2) defining a first guiding lumen (20) in an interior of the outer shaft (2); an inner shaft (3) movably arranged at least partially in the first guiding lumen (20), wherein the inner shaft (3) defines a second guiding lumen (30) in an interior of the inner shaft (3); and a dividing device (4) arranged in a proximal end region of the guiding catheter (1), the dividing device (4) having a first port (41) and a second port (42) angularly arranged to each other, wherein both the first port (41) and the second port (42) provide access to the first guiding lumen (20). According to an aspect of the invention, the inner shaft (3) extends through the second port (42) into the first guiding lumen (20), wherein the inner shaft (3) comprises at least section-wise a slit (32) along a longitudinal extension direction (F) of the inner shaft (3), wherein the slit (32) provides access to the second guiding lumen (30) and enables a working catheter (5) to enter the second guiding lumen (30) from the first guiding lumen (20).
A process for chemical crosslinking of tissue joining partners including crosslinkable groups, such as free amino groups, by a suitable crosslinking agent under static, quasi-static or periodic pulsatile pressure compression. The compression can be in a defined overlap region for seamless, dense and tight tissue closure. This results in a seamless, homogeneous, and at the same time mechanically stable connection/joining of tissue/tissue components. Seamless connected tissue is provided that includes a piece of tissue having at least two tissue parts overlapping each other and the at least two tissue parts overlapping each other that are materially bonded to each other via crosslinked groups of the tissue.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A process for three-dimensional shaping of a biological and/or artificial tissue/tissue component. The process is consistent for shaping tissues and can produce a desired three-dimensional and permanent shaping of the tissue/tissue component via crosslinking. A suitable crosslinking agent is used in combination with shaped body and a granulate.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
56.
Method for the production of crosslinked and optionally shaped tissue with selective adjustment of thickness, shape and/or flexibility
A method for chemically crosslinking and optionally shaping (including thickness reduction) substantially non-cross-linked tissue, in particular biological tissue, using a permeable material layer. The method can be used in combination with a stepless pressure load/compression on the tissue, so as to always allow fluid transport into and out of the tissue to be treated under the chemical cross-linking; along the lines of drainage. The method can be carried out under different pressure loads/compressions, in particular in order to specifically influence the resulting tissue properties, and, for example, to bring about a homogeneous thickness distribution of the tissue and/or to deliberately and specifically place inhomogeneities, if desired. Furthermore, the method allows the introduction/imprinting of a consistent three-dimensional shape into the tissue to be treated, e.g. of inhomogeneities in the thickness of the tissue.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
57.
HYDROPHILIC COATINGS FOR VASCULAR MEDICAL PRODUCTS
The present invention relates to use of a UV-sensitive copolymer and a hydrophilic coating containing the copolymer, for coating a surface of a vascular medical product. The UV-sensitive copolymer comprises repeating units of (a) vinylpyrrolidone, and (b) perfluorophenylazide, wherein the copolymer has a statistical distribution of the repeating units (a) and (b) and has a molecular weight of 5,000 to 50,000 g/mol. The invention further relates to a method for coating a surface of a vascular medical product, and the coated vascular medical products obtained.
The present invention relates to a medical system (1), preferably for exclusion of a left atrial appendage, comprising: a tissue forceps (2) configured to be inserted into the left atrium transseptally, to invert the left atrial appendage into the left atrium, and optionally to remove the severed left atrial appendage from the left atrium, a surgical connecting device (3) configured to be inserted into the left atrium transseptally and to apply at least one connection element (e.g. staple) to the inverted atrial appendage to close the inverted left atrial appendage in a blood-tight manner, the surgical connecting device (3) being optionally further configured to sever the closed inverted left atrial appendage at a base of the left atrial appendage, and a guiding structure (4) for guiding the surgical stapling device (3) along the tissue forceps (2) towards the inverted left atrial appendage.
A balloon catheter includes a balloon extending in an axial direction (z). The balloon includes an expandable balloon wall that extends around the balloon in a circumferential direction (U) and surrounds a balloon interior space of the balloon. The balloon interior space is configured to be filled with a fluid inflation medium. A capacitive sensor is configured to measure a diameter (D) extending in a radial direction (R) of the balloon. The sensor includes a capacitor having two planar and expandable electrodes arranged on the balloon wall.
The present invention, inter alia, relates to a method for preparing a biological material for a medical application comprising exposing the biological material to a first liquid, for example comprising, by at least 10%, a component other than water, and applying a first compression step onto the biological material, wherein the first compression step comprises repeatedly applying a compression force in a plurality of compression intervals. The method further comprises drying the biological material.
A61L 24/00 - Adhésifs ou ciments chirurgicauxAdhésifs pour dispositifs de colostomie
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A first aspect of invention relates a method for preparing a biodegradable biological tissue, preferably a collagen containing tissue. The (decellularized) biological tissue is first stabilized by a tissue water replacing material and then dried while applying an elevated pressure to the biological tissue. A second aspect of the invention relates to a method for producing a non-biodegradable biological tissue tube (i.e. hollow cylinder), preferably a collagen containing tissue tube.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
62.
CATHETER SYSTEM FOR IMPLANTING A MEDICAL IMPLANT TO FORM A MEDICAL BYPASS CONNECTION
A catheter system (1) for implanting a medical implant (2) to form a medical bypass connection on a vessel or between a first vessel and a second vessel comprises a medical implant (2) having a first end (20), a second end (21) and a body (22) forming a flow lumen (220). A catheter shaft (11) defines an inner lumen (110) and having a distal end (111), said medical implant (2) in a delivery state being received in said inner lumen (110) such that the first end (20) of the medical implant (2) is received in proximity to said distal end (111) of the catheter shaft (11) and the second end (21) is arranged proximally with respect to the first end (20), wherein the catheter shaft (11) is configured to be moved towards a vessel wall (W) to place the first end (20) of the medical implant (2) on the vessel wall (W). An actuating catheter (12) is received in said inner lumen (110) and has a tip (120) operatively connected to the second end (21) of the medical implant (2), wherein the actuating catheter (12) is movable with respect to the catheter shaft (11) for approaching the second end (21) of the medical implant (2) towards the first end (20) of the medical implant (2), said tip (120) being configured to penetrate the vessel wall (W) for moving the second end (21) of the medical implant (2) through the vessel wall (W).
A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose
A catheter device for performing a cardiac sympathetic denervation intervention includes an ablation device for applying an ablation action. The ablation device has an expansion member that is expandable from a compressed delivery state to an expanded ablation state. The expansion member includes an inner lumen defining a blood flow passage through the ablation device in the expanded ablation state of the expansion member in an antegrade flow direction (F). The catheter device is configured for introduction into the aorta to perform a cardiac sympathetic denervation intervention at an ablation site within the aorta. The expansion member is configured to abut, in the expanded ablation state, an aortic wall section (W) and carries an ablation arrangement for applying ablation action at the ablation site.
A61B 18/06 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage produit par des réactions chimiques
A61F 2/01 - Filtres implantables dans les vaisseaux sanguins
Minimally invasive medical devices for restoring fluid flow
in body vessels, medical devices for treating coronary heart
disease (CHD) and peripheral arterial disease, medical
devices for coronary vascular procedures and peripheral
vascular procedures, vascular and cardiovascular implants
and devices; catheters, stents, active substance delivery
stents, bioabsorbable and bioresorbable vascular supports
(armatures), active ingredient-releasing vascular supports,
bioabsorbable and bioresorbable braces, bioabsorbable and
bioresorbable vascular supports (armatures) of magnesium,
medical devices for administering medicines for local use
and regional use.
65.
PACKAGING ARRANGEMENT FOR A MEDICAL DEVICE AND CONNECTING ELEMENT FOR SUCH A PACKAGING ARRANGEMENT
A detachable connecting element is described comprising a first connecting element part (61) and a second connecting element part (62), wherein the first connecting element part (61) and the second connecting element part (62) are relatively movable to each other around a connecting element axis (R) by a rotational or helical movement to transfer the connecting element (6) from a linking state to a non-linking state and optionally vice versa, wherein the second connecting element part (62) comprises at least one protrusion (66, 65) and the first connecting element part (61) comprises at least one recess (63, 64) for incorporating one of the at least one protrusions (65, 66) of the second connecting element part (62).
B65D 21/02 - Réceptacles de forme spéciale ou pourvus de garnitures ou de pièces de fixation, pour faciliter l'emboîtement, le gerbage ou l'assemblage
A61B 50/30 - Récipients spécialement adaptés à l'emballage, la protection, la distribution, la collecte ou l'élimination des appareils ou des instruments chirurgicaux ou de diagnostic
The invention relates to a packaging arrangement for a medical device, the packaging arrangement (1) comprising at least one device recess (2, 20, 21) for receiving a medical device (5) and a loading basin (3) intended to receive a liquid (4) for manipulating a medical device (5) housed in the at least one device recess (2, 20, 21) or being intended to be connected to a medical device (5) housed in the at least one device recess (2, 20, 21). The packaging arrangement (1) further comprises a spillway basin (8), wherein the loading basin (3) is connected to the spillway basin (8) via a spillway passage (7) having a spillway passage inflow (31) and a spillway passage outflow (71), wherein the spillway passage (7) exhibits a downward slope from the spillway passage inflow (31) to the spillway passage outflow (71).
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
A system (1) for mounting a medical implant (2) to a delivery catheter (3) configured for delivering the medical implant (2) to an implantation site, wherein the system (1) comprises: a medical implant (2), wherein the medical implant (2) comprises a self-expandable scaffold (20); a delivery catheter (3) configured to deliver the medical implant (2) to an implantation site, wherein the delivery catheter (3) comprises a capsule (226) for covering the medical implant (2); a loading cone (4) for arranging a proximal end portion (20a) of the scaffold (20) in a crimped state by decreasing an outer diameter of the proximal end portion (20a) of the scaffold (20), wherein the loading cone (4) comprises a body (40) comprising a distal opening (41) for receiving the scaffold (20) and an opposing proximal opening (42), wherein the distal opening (41) comprises a diameter that is larger than a diameter of the proximal opening (42), and wherein the body (40) of the loading cone (4) further comprises an inner surface (40a) extending from the distal opening (41) to the proximal opening (42), wherein the inner surface (40) tapers towards the proximal opening (42); a loading tube (5) configured to be inserted into the proximal opening (42) of the loading cone (4) and to enclose the capsule (226) of the delivery catheter (4); wherein the loading cone (4) and the loading tube (5) are pre-mounted on the delivery catheter (3), and wherein the system (1) comprises a packaging (6) enclosing the delivery catheter (3) as well as the loading cone (4) and the loading tube (5) pre-mounted on the delivery catheter (3).
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
A61F 2/00 - Filtres implantables dans les vaisseaux sanguinsProthèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corpsAppareils pour les assujettir au corpsDispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p. ex. stents
The present invention relates to a packaging (100) for a medical device (150, 160, 170, 180, 185, 190), comprising: an outer packaging (110) defining an internal space of the outer packaging (110), and at least a first and a second tray (130, 140) configured to be arranged in the internal space of the outer packaging (110), wherein the second tray (140) comprises at least one protrusion (141) on a bottom side (140b) of the second tray (140), and wherein the first tray (130) comprises at least one recess (131) on a top side (130a) of the first tray (130), the at least one recess (131) being aligned with the at least one protrusion (141), wherein the second tray (140) is configured to be arranged on the first tray (130) so that the protrusion (141) engages with the recess (131).
A61B 50/30 - Récipients spécialement adaptés à l'emballage, la protection, la distribution, la collecte ou l'élimination des appareils ou des instruments chirurgicaux ou de diagnostic
Minimally invasive medical devices for restoring fluid flow in body vessels, medical devices for treating coronary heart disease (CHD) and peripheral arterial disease, medical devices for coronary vascular procedures and peripheral vascular procedures, vascular and cardiovascular implants and devices; catheters, stents, active substance delivery stents, bioabsorbable and bioresorbable vascular supports being armatures for providing support to the vessel wall and keep the vessel lumen open, active ingredient-releasing vascular supports for providing support to the vessel wall and keep the vessel lumen open, bioabsorbable and bioresorbable vascular supports being armatures of magnesium for providing support to the vessel wall and keep the vessel lumen open, medical devices for administering medicines for local use and regional use.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Resorbable and absorbable parts and components sold as an integral part of medical devices and implants to restore, maintain and promote optimal body function, namely metals, chemical compounds of metals and metal alloys. Conducting medical and clinical research and development in the field of coronary heart disease and peripheral arterial diseases; conducting clinical studies and trials to assess and evaluate the performance, safety and efficiency of medical devices for use in regulatory approval matters
71.
HYDRAULICALLY ACTUATED CATHETER LIKE SYSTEM FOR TREATING VASCULAR AND NON-VASCULAR DISEASES
The present invention, inter alia, relates to a catheter comprising a rolling membrane 1, wherein the rolling membrane is adapted to roll in a longitudinal direction along a vessel of a patient.
A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes
72.
A PROSTHETIC HEART VALVE WITH IMPROVED SEALING MEANS
A medical implant, such as a transcatheter deliverable endoprosthesis or a prosthetic heart valve including a stent-structure, one or more skirts and optionally a valve assembly. One or more skirts and/or the one or more leaflets include one or more laser markings that partially or fully penetrate a thickness of the one or more skirts and/or the one or more leaflets. The laser marks are preferably sufficiently big to be optically visible at the surface of the outer skirt by an operator during a sewing process. Each laser marking may be used for suturing, wherein the reduced material thickness eases the suturing/sewing process without compromising the structural integrity of the material of the outer skirt (e.g. a biological tissue
The invention relates to a computer implemented method for classifying or suggesting at least one medical device and/or at least one drug clinically associated with a first data set (DS1) of medical parameters of a patient, comprising the steps of providing (S1) a first data set (DS1) of medical parameters of a patient, applying (S2) a machine learning algorithm (A1) and/or a rule-based algorithm (A2) to the first data set (DS1) of medical parameters of the patient for classifying a medical device, in particular an implantable medical device, and/or drug clinically associated with the first data set (DS1) of medical parameters of the patient, and outputting (S3) a second data set (DS2) comprising at least one class (C) representing the at least one medical device and/or the at least one drug clinically associated with the first data set (DS1) of medical parameters of the patient. The invention further relates to a corresponding system and training method.
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
G16H 20/00 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
The invention relates to a computer implemented method and system for virtual vascular intervention, in particular for vascular interventions, comprising the steps of applying (S4) a machine learning algorithm (A1) to the pre-acquired first data set (DS1) of medical image data of a patient (P) and the second data set (DS2) of patient medical parameters and/or natural language data related to a medical condition of the patient (P) to identify at least one pathological feature (10) comprised by the pre-acquired first data set (DS1) of the medical image data of the patient (P) and the pre-acquired second data set (DS2) of patient medical parameters and/or natural language data related to a medical condition of the patient (P), wherein the identified at least one pathological feature (10) is indicated in the three-dimensional virtual model (M) of the at least one portion of the body of the patient (P).
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
The present invention relates to a folding box (1) for enclosing a medical device (2), the folding box comprising: a bottom (10), a circumferential lateral wall (11) connected to the bottom (10), the lateral wall (11) comprising a front wall portion (110) and an opposing rear wall portion (111), and a lid (12) hinged to the rear wall portion (111), so that the lid (12) is pivotable in an open state of the folding box (1), the lid (12) configured to be connected to the lateral wall (11) in a closed state of the folding box (1) to prevent pivoting open of the lid (12), and wherein the lid (12) comprises an edge region (120a), wherein the lid (12) comprises a panel (120) forming said edge region (120a), the panel (120) extending opposite the bottom (10) in the closed state of the folding box (1), wherein the panel (120) comprises two front flaps (121) each being connected to the panel (120) via a crease (121a), wherein said edge region (120a) is arranged between said two front flaps (121), wherein the two front flaps (121) are configured to be connected to an outside (110a) of the front wall portion (110) in the closed state of the folding box (1) such that said slot (113) is delimited by the front wall portion (110), said edge region (120a) and the two front flaps (121). According to the present invention, the folding box (1) comprises a slot (13) arranged between said edge region (120a) and the front wall portion (110) in the closed state of the folding box (1) to allow insertion of a package information leaflet (14) through the slot (13) into an internal space (3) of the folding box (1). Further, the folding box comprises a wing (130) being integrally connected to the front wall portion (110) via a crease (130a) and configured to protrude from the front wall portion (110) along the panel (120) of the lid (12) when the folding box (1) is in the closed state.
Medical occlusion devices (100, 200, 300, 400) for occluding abnormality or defects in a body lumen or a cardiovascular structure, for example a left atrial appendage (LAA), having improved positioning properties are disclosed. Further, a system comprising such medical occlusion device and a catheter is disclosed.
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical
77.
DILATOR SHAFT DESIGN ENABLING TIP SHAPABILITY AND VARIABLE SHAFT FLEXIBILITY
A dilator (3) for an endovascular treatment of a lesion within a patient comprises a dilator shaft (33) extending along a longitudinal axis (L), the dilator shaft (33) having a braid (31) comprising an arrangement of braid threads (310, 311) woven to form the braid (31). A first group of the braid threads (310) and a second group of the braid threads (311) are woven with one another and are arranged to cross one another at an angle (α, β) therebetween. Herein, at a first axial location of the dilator shaft (33) said first group of the braid threads (310) and said second group of the braid threads (311) are arranged to cross one another at a first angle therebetween, and at a second axial location of the dilator shaft (33) said first group of the braid threads (310) and said second group of the braid threads (311) are arranged to cross one another at a second angle therebetween different than said first angle.
A dilator (3) for an endovascular treatment of a lesion within a patient comprises a dilator shaft (33) extending along a longitudinal axis (L), the dilator shaft (33) having a braid (31) comprising an arrangement of braid threads (310, 311) woven to form the braid (31). A first group of the braid threads (310) and a second group of the braid threads (311) are woven with one another and are arranged to cross one another at an angle (?, ?) therebetween. Herein, at a first axial location of the dilator shaft (33) said first group of the braid threads (310) and said second group of the braid threads (311) are arranged to cross one another at a first angle therebetween, and at a second axial location of the dilator shaft (33) said first group of the braid threads (310) and said second group of the braid threads (311) are arranged to cross one another at a second angle therebetween different than said first angle.
The present invention relates to a medical implant (2) for connecting a first and a second tissue portion to one another, comprising: a first and a second fixation member (20, 22), a connection structure (21), wherein the first fixation member (20) is connected to the second fixation member (22) via the connection structure (21), and wherein the first fixation member (20) is configured to engage with the first tissue portion, and wherein the second fixation member is configured to engage with the second tissue portion such that the connection structure (21) extends between the tissue portions to connect the tissue portions to one another.
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 17/11 - Instruments, dispositifs ou procédés chirurgicaux pour refermer les plaies ou les maintenir ferméesAccessoires utilisés en liaison avec ces opérations pour réaliser l'anastomoseBoutons pour anastomose
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 17/122 - Clamps ou pinces, p. ex. pour le cordon ombilical
A61B 17/128 - Instruments, dispositifs ou procédés chirurgicaux pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p. ex. les vaisseaux sanguins ou le cordon ombilical pour appliquer ou enlever les clamps ou les pinces
An absorber device for absorbing a fluid residing in an a package inner space. The absorber device includes an absorber arranged in the inner space of a container and a movable penetration device. The penetration device is configured to be moved from a first position to a second position. In the first position, the penetration device is positioned in the inner space of the container. In the second position, the penetration device is configured to penetrate a container contact section and a wall of the package. The absorber in the inner space of the container is thereby fluidically connected to the inner space of the package in the second position.
B65D 81/26 - Adaptations pour empêcher la détérioration ou l'altération du contenuApplications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux avec dispositifs pour évacuer ou absorber les fluides, p. ex. s'écoulant du contenuEmploi de produits empêchant la corrosion ou de dessiccateurs
A heart valve prosthesis includes a valve member having a flexible leaflet arrangement and a valvular support structure to support the flexible leaflet arrangement. The flexible leaflet arrangement includes a plurality of flexible leaflets. Each flexible leaflet forms a free edge. The free edges are configured to abut one another in a closed position to block blood flow in a retrograde flow direction. When viewed in a cross-sectional plane transverse to the antegrade flow direction, a first of the flexible leaflets extends across a first opening angle and a second of the flexible leaflets extends across a second opening angle different from the first opening angle. The free edge the first of the flexible leaflets has a first convex curvature and the free edge of the second of the flexible leaflets has a second convex curvature different than the first convex curvature.
A catheter system is described comprising an outer catheter having an outer catheter shaft defining an outer catheter lumen capable of receiving at least one inner member, at least one inner member being arranged within the outer catheter lumen of the outer catheter, the at least one inner member being relatively movable to the outer catheter in an unrestricted moving state, and an axial movement restriction element comprising an actuation mechanism and a locking mechanism, wherein the axial movement restriction element is capable of restricting an axial movement of the at least one inner member in a restricted moving state compared to the axial movement in the unrestricted moving state. Furthermore, a method for operating a catheter system is described.
A crossing catheter system for crossing chronic total occlusion is described comprising or consisting of a support catheter having a support catheter shaft defining a support catheter lumen capable of receiving a dilator, a dilator being arranged within the support catheter lumen of the support catheter, and a locking handle arranged at a proximal support catheter end and optionally at least one manifold. Furthermore, a method of operating such a crossing catheter system is described.
A61B 17/22 - Instruments pour comprimer les ulcères ou similaires placés sur les organes internes du corpsInstruments pour curer les cavités des organes du corps, p. ex. des osInstruments, dispositifs ou procédés chirurgicaux pour l'élimination ou la destruction invasives des calculs utilisant des vibrations mécaniquesInstruments, dispositifs ou procédés chirurgicaux pour l'élimination non prévue ailleurs des obstructions dans les vaisseaux sanguins
A61M 29/00 - Dilatateurs avec ou sans moyens pour introduire des agents, p. ex. des remèdes
A catheter device for implanting a medical implant includes an actuating element configured to move with a capsule of the catheter device and to be manually operated to bring the actuating element from a first state to a second state. A first and/or second stop is included in the catheter device. The first stop is configured to limit a movement of the actuating element and therewith of the capsule in a first direction, e.g. proximal direction (P), when the actuating element is in the first state. The second stop is configured to limit a movement of the actuating element and therewith of the capsule in a second direction, e.g. distal direction (D), when the actuating element is in the first state, so as to prevent pressing of the capsule against a catheter tip of the catheter device and/or against a capsule stop of the catheter device.
A catheter includes a positional identifier / marker at a tip section for a medical implant that needs to be aligned rotationally and/or axially and/or in terms of tilting in a human or animal body. The positional identifier is shaped and/or arranged such that a rotational orientation and/or an axial orientation and/or a tilted orientation of the tip section relative to the surrounding tissue is discernable from the position and/or orientation of the positional identifier
A protective device for an elongate catheter carrying a functional element, in particular a stent or a balloon, in particular a balloon coated with an active substance, on a distal end portion of the catheter. The protective device includes a protector configured to be arranged on the distal end portion so that the functional element is surrounded by the protector. A protective sleeve surrounds an interior to receive the catheter together with the protector. The protective sleeve has at least one projection on an inner side of the protective sleeve facing the interior of the protective sleeve. The projection is configured to retain the protector when the catheter together with the protector is arranged in the interior of the protective sleeve and the catheter is withdrawn from the protective sleeve so that the protector is pulled off the distal end portion of the catheter.
A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes
The invention relates implants (1) comprising at least one biodegradable support structure (2) and at least one covering material at least partially covering the at least one biodegradable support structure (2) already prior to implantation, wherein the covering material is selected from an autologous, xenogeneic or allogeneic material or combinations thereof, and wherein the biodegradable support structure consists of magnesium, zinc or iron; or the biodegradable support structure consists of a biodegradable magnesium-based alloy, a biodegradable zinc-based alloy or a biodegradable an iron-based alloy.
A61L 27/36 - Matériaux pour prothèses ou pour revêtement de prothèses contenant des constituants de constitution indéterminée ou leurs produits réactionnels
A61L 27/58 - Matériaux au moins partiellement résorbables par le corps
A61L 31/00 - Matériaux pour autres articles chirurgicaux
An artificial heart valve includes support structure having a first end and second end and defining an interior of the valve. A covering covers the support structure and includes an intermediate portion with a plurality of intermediate strip-shaped sections having cuts between them. Some are attached to the stent and others are not so that a closed configuration prevents retrograde blood flow into an interior of the stent with the free strip-shaped sections abutting the stent and overlapping or abutting the attached strip-shaped sections to prevent retrograde blood flow into the interior. An open configuration is formed with the unattached strip-shaped sections lifting from the stent to allow antegrade blood flow from the interior of the stent.
A method for producing a balloon for a balloon catheter includes providing the balloon that has an outer surface. A solution including a solvent and a polymer is used to deposit the polymer onto the surface and form a surface coating of the polymer.
Described is a method for producing a tubular semi-finished product (10) for an implant scaffold which leads to an improvement of the dilatability of the scaffold, wherein the semi-finished product (10) consists of a magnesium alloy, said method having the following steps: a) extruding the tubular semi-finished product (10) by means of a heated die (3) or tempering the extruded tubular semi-finished product by means of a heating device; b) introducing into the material of the semi-finished product (10) exiting from the die (3) or the heating device a tensile stress and/or a torsional stress by means of a tube drawing device (13), which has a clamping device (19), wherein the clamping device is fixed on a predefined portion (20) of the tubular semi-finished product (10) and the tensile force generated by the tube drawing device (13) and/or the torsion moment generated by the tube drawing device (10) transfers to the semi-finished product (10). A corresponding device is also described.
The present invention relates to a catheter device (1) for implanting a medical implant (100), particularly a prosthetic heart valve such as a prosthetic aortic heart valve, wherein the device (1) comprising a handle (70) for controlling/steering multiple sheaths 10, 20, 60 of the catheter device (1).
A balloon catheter system includes a balloon extending in an axial direction. A stent is crimped onto an outer surface of the balloon. A catheter is connected to the balloon and includes a lumen in fluid communication with a balloon interior of the balloon. At least one sensor associated with the balloon measures expansion of the balloon in a radial direction (R). A processing unit receives a signal from the at least one sensor and is connected to terminate filling of the balloon interior with a fluid medium (M) and/or to prompt a display device to output a display if the signal reaches a threshold value above a predefined reference value, the signal being indicative of a current diameter (D) of the balloon in the radial direction (R), the reference value corresponding to a balloon diameter upon contact of a proximal and/or distal balloon end with a vessel wall, and the threshold value exceeding the reference value by 5% to 20%.
A61F 2/958 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes ballons gonflables pour insérer les stents ou les endoprothèses déployables couvertes
94.
CATHETER HAVING CONNECTOR WITH ELECTRICAL CONDUCTOR CONNECTIONS
A catheter includes a catheter shaft with an outer surface extending from a proximal end portion to a distal end portion of the catheter shaft. A connector is connected to the proximal end portion of the catheter shaft. A material surrounds the proximal end portion. A printed circuit board is embedded in the material. The printed circuit board has a conductor track. At least one electrical conductor is printed on the outer surface of the catheter shaft. The at least one electrical conductor contacts the conductor track so that the at least one electrical conductor and the at least one conductor track are electrically conductively connected.
A processing system including a processing unit is configured to be connected to a catheter in a releasable fashion via a connecter portion of a housing. The processing unit is configured to exchange data with a component of the catheter and at least one of a database, a computer network, and a computer device. The processing unit includes an integrated circuit for processing the data.
An implant includes a tubular discontinuous structure formed of a plurality of webs that at least partially extend in a longitudinal direction. The plurality of webs includes at least one joint element having a main web substantially extending in the longitudinal direction. There is a continuous gap in the main web. At least one bridge web is arranged next to the main web in a circumferential direction (U) and connected to the main web in the longitudinal direction (A) in front of and behind the gap.
A61F 2/915 - Stents ayant une forme caractérisée par des éléments filiformesStents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles fabriquée à partir de feuilles perforées ou de tubes perforés, p. ex. perforés par découpe au laser ou gravés avec des bandes présentant une structure en méandre, des bandes adjacentes étant reliées l’une à l’autre
A61F 2/962 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes possédant une gaine extérieure
The present invention relates to a method for producing a swellable body (10) comprising bacterial cellulose, wherein the method comprises the steps of: providing a body (10) made of bacterial cellulose, cleaning the body (10) using at least one liquid medium, and freeze-drying the body (10).
A method for connecting an X-ray marker to a base body of an implant is provided. The based body includes a receptacle for receiving an X-ray marker. A flexible film and an X-ray marker are arranged so that at least a section of the film is located between the receptacle and the X-ray marker. The X-ray marker is pressed into the receptacle while interposing the film so that the X-ray marker is plastically deformed and, together with the film, is fixed in a force-fit manner in the receptacle. The film prevents contact between the X-ray marker and the base body.
B29C 65/20 - Assemblage d'éléments préformésAppareils à cet effet par chauffage, avec ou sans pressage avec un outil chauffé à contact direct, p. ex. avec un "miroir"
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
B29C 65/44 - Assemblage d'un élément en matière autre que plastique chauffé avec un élément en matière plastique
B29C 65/00 - Assemblage d'éléments préformésAppareils à cet effet
99.
CATHETER DEVICE FOR DELIVERING A MEDICAL IMPLANT ALLOWING OVERTRAVEL OF A CAPSULE OF THE CATHETER DEVICE
The present invention relates to a catheter device (1) for implanting a medical implant,wherein a handle (70) of the device (1) comprises a locking element (80) that is configured to be moved from a first to a second state, wherein the locking element (80) limits a movement of a traveler (76) and therewith of a capsule (40) of the device in a distal direction (D) in the first state, and wherein the locking element (80) allows further movement of the traveler (76) and therewith of the capsule (40) in the distal direction (D) in the second state.
A61F 2/962 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes possédant une gaine extérieure
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
100.
PROSTHETIC HEART VALVE COMPRISING A STENT STRUCTURE
The present invention relates to a vascular implant, in particular a prosthetic heart valve, for providing a valve function, comprising a stent structure with a proximal conical-convex inflow region and a distal, linear cylindrical outflow region, and a corresponding valve arrangement.
