A traditional Chinese medicine composition for treating thyroid nodules, lipomas, mammary gland hyperplasia and mouth ulcers, the composition comprising as a primary formula of main active ingredients three medicinal/edible source materials consisting of: Lonicera japonica or Lonicera hypoglauca or a mixture of Lonicera japonica and Lonicera hypoglauca, and Taxacum and Prunella vulgaris. The foundation of the primary formula is supplemented by a secondary formula consisting of Scleromitrion diffusa, Hippophae rhamnoides, Poncirus trifoliata and Pholidota, and different preparations are prepared, suitable for different types of thyroid nodules. The traditional Chinese medicine combined formula can be a combined formula of source herbs, and can likewise be a combined formula of extracts thereof, and can likewise be a combined formula of source herbs and extracts. The traditional Chinese medicine composition has a significant therapeutic effect on symptoms of an enlarged thyroid gland caused by inflammation, autoimmunity and new organisms.
A traditional Chinese medicine composition for treating abnormal lung function and laryngitis caused by the influenza virus; the traditional Chinese medicine composition comprising as a primary formula of active ingredients seven medicinal/edible source materials composed of: Siraitia grosvenorii, Cinnamomum cassia, Prunella vulgaris, Houttuynia cordata, Platycodon grandiflorus, Gardenia jasminoides and Glycyrrhiza uralensis. The foundation of the primary formula is supplemented by a secondary formula of seven medicinal/edible source materials consisting of: Citrus reticulata (mandarin orange), Eriobotrya japonica leaves, Angelica dahurica, Arctium lappa root, Piper nigrum, Phragmites australis root and Syzygium aromaticum, and different preparations are prepared. The traditional Chinese medicine combined formula can be a combined formula of source herbs, and can likewise be a combined formula of extracts thereof, and can likewise be a combined formula of source herbs and extracts. The traditional Chinese medicine composition has a significant therapeutic effect on symptoms such as sore throat, itchy throat cough, swelling and pain in the throat, pharyngeal discomfort, etc. resulting from influenza-caused pneumonia such as abnormal lung function and difficulty breathing, cough, lung nodules, ground glass opacity in the lungs, pulmonary fibrosis, interstitial lung disease and laryngitis, and has a certain relieving, progression-stopping and disease condition control and treatment effects on chronic obstructive emphysema.
The present invention relates to a pharmaceutical cocrystal of curcumin, a preparation method therefor, and the use thereof as a drug or in a pharmaceutical preparation. The pharmaceutical cocrystal of curcumin has a good solubility, a good stability, a process developability, etc., and the preparation method therefor is simple and low in cost, which hold an important value for the optimization and development of the drug in the future.
C07C 49/255 - Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
C07C 59/64 - Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
C07C 65/03 - Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
C07C 45/81 - SeparationPurificationStabilisationUse of additives by change in the physical state, e.g. crystallisation
C07C 51/43 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
4.
OSIMERTINIB CO-CRYSTAL, PREPARATION METHOD, AND APPLICATION AS DRUG OR IN PHARMACEUTICAL FORMULATION
Involved are an osimertinib co-crystal, a preparation method therefor, and an application thereof as a drug or in a pharmaceutical formulation, more particularly for treating non-small cell lung cancer. The co-crystal has good solubility, good stability and process developability and the like; and the preparation method is simple and low in cost, and has an important value for optimization and development of the drug in the future.
C07D 403/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
The present invention relates to a cocrystal of cabozantinib, a preparation method therefor and an application thereof as a drug or in a pharmaceutical preparation, more particularly an application for the treatment of progressive medullary thyroid carcinoma (MTC), kidney cancer, and prostate cancer. The cocrystal has good solubility, better stability and process developability, etc., and the preparation method is simple and low in cost, and has important values for optimization and development of the drug in the future.
A pharmaceutical use of a pharmaceutical composition containing platinum drugs or platinum drug co-crystals as main active substances in preventing or treating immunological diseases such as rheumatoid arthritis, and other diseases. The platinum drugs mainly refer to oxaliplatin, and the platinum drug co-crystals mainly refer to carboplatin co-crystals or oxaliplatin co-crystals. Further disclosed is a method using platinum drugs or platinum drug co-crystals, either alone or in combination with at least one additional therapeutic agent or adjuvant therapy agent.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Chinese traditional medicinal herbs; Dietary and nutritional supplements; Dietary food supplements; Dietary supplements for human consumption; Dietetic foods and beverages adapted for medical use; Herb teas for medicinal purposes; Medicinal tea; Pharmaceutical preparations for treating diabetes; Pharmaceutical products for the prevention and treatment of cancer; Plant extracts for pharmaceutical purposes
8.
COMBINATION PRODUCT COMPRISING DICYCLOPLATIN AND PREPARATION METHOD AND USE THEREOF
The present invention relates to the compositions containing dicycloplatin, pharmaceutical use of the compositions in the treatment and/or prevention of pain, inflammation and virus-related diseases, and methods of preparing the compostions thereof.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Tonics of medicines, namely, medicinal tea; Medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in preventing prostatitis, benign prostatic hyperplasia, urinary tract infection, gynecological inflammation, gastrointestinal disease; Medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in blood sugar regulation, liver protection, and as antioxidants, anti-hyperlipidemia, anti-aging, antineoplastic and antiviral agents for medical use; Medicines for human purposes, namely, medicines for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Medicinal drinks; Capsules sold empty for pharmaceuticals; Pharmaceutical preparations for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Chemico-pharmaceutical preparations for tumor-suppression and antiviral treatment; Troches, namely, tablets for use in tumor-suppression, as antivirals and for the treatment of chronic gastrointestinal disease; Tinctura in the nature of medicinal herb extracts; Herbs for medicinal purposes; Nutritional supplements; dietetic foods adapted for medical use, namely, dietetic drinks, dietetic crackers, dietetic sugar for medical use, dietetic sugar substitutes for medical use; Dietary and nutritional supplements; Dietary food supplements; Dietary supplemental drinks; Dietary supplements; Dietetic beverages adapted for medical use; Dietetic foods adapted for medical purposes; Dietetic foods and beverages adapted for medical use; Nutraceuticals for use as a dietary supplement; Nutritional supplements in the form of capsules, tablets, caplets, powder, syrups, gummies and gels; Sanitizing preparations for commercial use
10.
COMBINATION PRODUCT COMPRISING DICYCLOPLATIN AND PREPARATION METHOD AND USE THEREOF
The present invention relates to a combination product comprising dicycloplatin, a use of the combination product in preparing a drug for treating and/or preventing pain, inflammation, or a disease related to a virus, and a method for preparing the combination product.
The present invention relates to a combination product comprising dicycloplatin, a use of the combination product in preparing a drug for treating and/or preventing pain, inflammation, or a disease related to a virus, and a method for preparing the combination product.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
30 - Basic staples, tea, coffee, baked goods and confectionery
32 - Beers; non-alcoholic beverages
Goods & Services
Tonics [medicines]; medicines for human purposes; medicinal
drinks; capsules for medicines; pharmaceutical preparations;
chemico-pharmaceutical preparations; pre-filled syringes for
medical purposes; lozenges for pharmaceutical purposes;
crude drugs; traditional Chinese medicines. Urological apparatus and instruments; sprayers for medical
purposes; aerosol masks for medical purposes; apparatus for
use in medical analysis; testing apparatus for medical
purposes; massage apparatus; medical apparatus and
instruments; receptacles for applying medicines;
vibromassage apparatus; fumigation apparatus for medical
purposes. Pastries; condiments; bechamel; leaven; essences for
foodstuffs, except etheric essences and essential oils;
vanilla [flavoring]; vegetal preparations for use as coffee
substitutes; tea; tea-based beverages; natural sweeteners. Non-alcoholic beverages; isotonic beverages; vegetable
beverages.
Beer; Water beverages; Non-alcoholic malt beverages; Non-alcoholic beverages containing fruit juices; Non-alcoholic water-based beverages; Aerated water; Non-alcoholic beverages flavored with tea; Vegetable drink; Preparations for making beverages, namely, fruit drinks; Syrups for beverages; Concentrates and powders used in the preparation of energy drinks and fruit-flavored beverages; Energy drinks; Energy drinks enhanced with vitamins, minerals, nutrients; Isotonic beverages; Isotonic drinks; Isotonic non-alcoholic drinks; Powders used in the preparation of isotonic sports drinks and sports beverages; Protein-enriched sports beverages; Sports drinks; Sports drinks enhanced with vitamins, minerals, nutrients; Sports drinks, namely, energy drinks; Sports drinks, namely, performance drinks; Whey beverages
05 - Pharmaceutical, veterinary and sanitary products
32 - Beers; non-alcoholic beverages
Goods & Services
Tonics of medicines, namely, medicinal tea; medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in preventing prostatitis, benign prostatic hyperplasia, urinary tract infection, gynecological inflammation, gastrointestinal disease; medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in blood sugar regulation, liver protection, and as antioxidants, anti-hyperlipidemia, anti-aging, antineoplastic and antiviral agents for medical use; Medicines for human purposes, namely, medicines for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, rhinitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Medicinal drinks; Capsules sold empty for pharmaceuticals; Pharmaceutical preparations for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Chemical-pharmaceutical preparations for tumor-suppression and antiviral treatment; Injectable syringes sold filled with vaccines, antivirals and tumor-suppression agents; Troches, namely, tablets for use in tumor-suppression, as antivirals and for the treatment of chronic gastrointestinal disease; Tinctures in the nature of medicinal herb extracts; Tincture of iodine; Tinctures in the nature of antiseptics for use in the treatment of traumatic injuries; Herbs for medicinal purposes; Nutritional supplements; Dietetic foods, namely, dietetic crackers, dietetic sugar for medical use, Dietetic sugar substitutes for medical use; Dietary and nutritional supplements; Dietary food supplements; Dietary supplemental drinks; Dietary supplements; Dietetic beverages adapted for medical use; Dietetic foods adapted for medical purposes; Dietetic foods and beverages adapted for medical use; Nutraceuticals for use as a dietary supplement; Nutritional supplements in the form of capsules, tablets, caplets, powder, syrups, gummies and gels Beer; Water beverages; Non-alcoholic malt beverages; Non-alcoholic beverages containing fruit juices; Non-alcoholic water-based beverages; Aerated water; Non-alcoholic beverages flavored with tea; Vegetable drink; Preparations for making beverages, namely, fruit drinks; Syrups for beverages; Concentrates and powders used in the preparation of energy drinks and fruit-flavored beverages; Energy drinks; Energy drinks enhanced with vitamins, minerals, nutrients; Isotonic beverages; Isotonic drinks; Isotonic non-alcoholic drinks; Powders used in the preparation of isotonic sports drinks and sports beverages; Protein-enriched sports beverages; Sports drinks; Sports drinks enhanced with vitamins, minerals, nutrients; Sports drinks, namely, energy drinks; Sports drinks, namely, performance drinks; Whey beverages
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
30 - Basic staples, tea, coffee, baked goods and confectionery
32 - Beers; non-alcoholic beverages
Goods & Services
Medicinal tonics for the treatment of cancer, prostatitis, benign prostatic hyperplasia, Alzheimer's disease, rheumatoid arthritis, bone injury diseases, thyroid nodules, diabetes, HBV, HIV, fatty liver disease, and alcoholic liver disease; medicines for human purposes for the treatment of cancer, prostatitis, benign prostatic hyperplasia, Alzheimer's disease, rheumatoid arthritis, bone injury diseases, thyroid nodules, diabetes, HBV, HIV, fatty liver disease, and alcoholic liver disease; medicinal drinks; capsules for medicines sold empty; pharmaceutical preparations for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; chemical-pharmaceutical preparations for the treatment of cancer, prostatitis, benign prostatic hyperplasia, Alzheimer's disease, rheumatoid arthritis, bone injury diseases, thyroid nodules, diabetes, HBV, HIV, fatty liver disease, and alcoholic liver disease; pre-filled syringes for medical purposes for the treatment of cancer, asthma, and insomnia; medicated lozenges for pharmaceutical purposes; traditional Chinese medicines in the nature of medicinal herbs Urological surgical apparatus and instruments; medical sprayers for cleaning gums and teeth used in dentists' offices during dental procedures; aerosol masks for medical purposes; apparatus for use in medical analysis, namely, stethoscopes and X-ray CT scanners; testing apparatus for medical purposes, namely, surgical microscopes and X-ray CT scanners; massage apparatus; medical apparatus and instruments, namely, stethoscopes and X-ray CT scanners; receptacles for applying medicines, namely, insulin injectors sold empty and implantable subcutaneous drug delivery devices sold empty; vibromassage apparatus; fumigation apparatus for medical purposes Pastries; condiments, namely, chutney, minced garlic, and prepared horseradish; béchamel sauce; food leavening agents; food flavorings being non-essential oils; vanilla flavorings for food or beverages; vegetal preparations for use as coffee substitutes; tea; tea-based beverages; natural sweeteners Non-alcoholic beverages, namely, fruit drinks, soda pop, and drinking water; isotonic beverages; vegetable beverages
The present invention relates to a process to prepare dicycloplatin under mild reactive conditions and at fast reaction rates. The process is reproducible and easy to scale up for industrial application.
The present invention relates to a process to prepare dicycloplatin under mild reactive conditions and at fast reaction rates. The process is reproducible and easy to scale up for industrial application.
