A traditional Chinese medicine composition for treating thyroid nodules, lipomas, mammary gland hyperplasia and mouth ulcers, the composition comprising as a primary formula of main active ingredients three medicinal/edible source materials consisting of: Lonicera japonica or Lonicera hypoglauca or a mixture of Lonicera japonica and Lonicera hypoglauca, and Taxacum and Prunella vulgaris. The foundation of the primary formula is supplemented by a secondary formula consisting of Scleromitrion diffusa, Hippophae rhamnoides, Poncirus trifoliata and Pholidota, and different preparations are prepared, suitable for different types of thyroid nodules. The traditional Chinese medicine combined formula can be a combined formula of source herbs, and can likewise be a combined formula of extracts thereof, and can likewise be a combined formula of source herbs and extracts. The traditional Chinese medicine composition has a significant therapeutic effect on symptoms of an enlarged thyroid gland caused by inflammation, autoimmunity and new organisms.
A traditional Chinese medicine composition for treating abnormal lung function and laryngitis caused by the influenza virus; the traditional Chinese medicine composition comprising as a primary formula of active ingredients seven medicinal/edible source materials composed of: Siraitia grosvenorii, Cinnamomum cassia, Prunella vulgaris, Houttuynia cordata, Platycodon grandiflorus, Gardenia jasminoides and Glycyrrhiza uralensis. The foundation of the primary formula is supplemented by a secondary formula of seven medicinal/edible source materials consisting of: Citrus reticulata (mandarin orange), Eriobotrya japonica leaves, Angelica dahurica, Arctium lappa root, Piper nigrum, Phragmites australis root and Syzygium aromaticum, and different preparations are prepared. The traditional Chinese medicine combined formula can be a combined formula of source herbs, and can likewise be a combined formula of extracts thereof, and can likewise be a combined formula of source herbs and extracts. The traditional Chinese medicine composition has a significant therapeutic effect on symptoms such as sore throat, itchy throat cough, swelling and pain in the throat, pharyngeal discomfort, etc. resulting from influenza-caused pneumonia such as abnormal lung function and difficulty breathing, cough, lung nodules, ground glass opacity in the lungs, pulmonary fibrosis, interstitial lung disease and laryngitis, and has a certain relieving, progression-stopping and disease condition control and treatment effects on chronic obstructive emphysema.
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
The present invention relates to a pharmaceutical cocrystal of curcumin, a preparation method therefor, and the use thereof as a drug or in a pharmaceutical preparation. The pharmaceutical cocrystal of curcumin has a good solubility, a good stability, a process developability, etc., and the preparation method therefor is simple and low in cost, which hold an important value for the optimization and development of the drug in the future.
C07C 49/255 - Composés non saturés comportant des groupes cétone liés à des atomes de carbone acycliques contenant des groupes éther, des groupes , des groupes ou des groupes
C07C 59/64 - Composés non saturés contenant des groupes éther, des groupes , des groupes ou des groupes contenant des cycles aromatiques à six chaînons
C07C 65/03 - Composés monocycliques ayant tous leurs groupes hydroxyle ou O-métal liés au cycle
C07C 45/81 - SéparationPurificationStabilisationEmploi d'additifs par modification de l'état physique, p. ex. par cristallisation
C07C 51/43 - SéparationPurificationStabilisationEmploi d'additifs par changement de l'état physique, p. ex. par cristallisation
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
4.
OSIMERTINIB CO-CRYSTAL, PREPARATION METHOD, AND APPLICATION AS DRUG OR IN PHARMACEUTICAL FORMULATION
Involved are an osimertinib co-crystal, a preparation method therefor, and an application thereof as a drug or in a pharmaceutical formulation, more particularly for treating non-small cell lung cancer. The co-crystal has good solubility, good stability and process developability and the like; and the preparation method is simple and low in cost, and has an important value for optimization and development of the drug in the future.
C07D 403/04 - Composés hétérocycliques contenant plusieurs hétérocycles, comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus par le groupe contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
The present invention relates to a cocrystal of cabozantinib, a preparation method therefor and an application thereof as a drug or in a pharmaceutical preparation, more particularly an application for the treatment of progressive medullary thyroid carcinoma (MTC), kidney cancer, and prostate cancer. The cocrystal has good solubility, better stability and process developability, etc., and the preparation method is simple and low in cost, and has important values for optimization and development of the drug in the future.
A pharmaceutical use of a pharmaceutical composition containing platinum drugs or platinum drug co-crystals as main active substances in preventing or treating immunological diseases such as rheumatoid arthritis, and other diseases. The platinum drugs mainly refer to oxaliplatin, and the platinum drug co-crystals mainly refer to carboplatin co-crystals or oxaliplatin co-crystals. Further disclosed is a method using platinum drugs or platinum drug co-crystals, either alone or in combination with at least one additional therapeutic agent or adjuvant therapy agent.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Chinese traditional medicinal herbs; Dietary and nutritional supplements; Dietary food supplements; Dietary supplements for human consumption; Dietetic foods and beverages adapted for medical use; Herb teas for medicinal purposes; Medicinal tea; Pharmaceutical preparations for treating diabetes; Pharmaceutical products for the prevention and treatment of cancer; Plant extracts for pharmaceutical purposes
8.
COMBINATION PRODUCT COMPRISING DICYCLOPLATIN AND PREPARATION METHOD AND USE THEREOF
The present invention relates to the compositions containing dicycloplatin, pharmaceutical use of the compositions in the treatment and/or prevention of pain, inflammation and virus-related diseases, and methods of preparing the compostions thereof.
C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Tonics of medicines, namely, medicinal tea; Medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in preventing prostatitis, benign prostatic hyperplasia, urinary tract infection, gynecological inflammation, gastrointestinal disease; Medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in blood sugar regulation, liver protection, and as antioxidants, anti-hyperlipidemia, anti-aging, antineoplastic and antiviral agents for medical use; Medicines for human purposes, namely, medicines for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Medicinal drinks; Capsules sold empty for pharmaceuticals; Pharmaceutical preparations for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Chemico-pharmaceutical preparations for tumor-suppression and antiviral treatment; Troches, namely, tablets for use in tumor-suppression, as antivirals and for the treatment of chronic gastrointestinal disease; Tinctura in the nature of medicinal herb extracts; Herbs for medicinal purposes; Nutritional supplements; dietetic foods adapted for medical use, namely, dietetic drinks, dietetic crackers, dietetic sugar for medical use, dietetic sugar substitutes for medical use; Dietary and nutritional supplements; Dietary food supplements; Dietary supplemental drinks; Dietary supplements; Dietetic beverages adapted for medical use; Dietetic foods adapted for medical purposes; Dietetic foods and beverages adapted for medical use; Nutraceuticals for use as a dietary supplement; Nutritional supplements in the form of capsules, tablets, caplets, powder, syrups, gummies and gels; Sanitizing preparations for commercial use
10.
COMBINATION PRODUCT COMPRISING DICYCLOPLATIN AND PREPARATION METHOD AND USE THEREOF
The present invention relates to a combination product comprising dicycloplatin, a use of the combination product in preparing a drug for treating and/or preventing pain, inflammation, or a disease related to a virus, and a method for preparing the combination product.
C07F 15/00 - Composés contenant des éléments des groupes 8, 9, 10 ou 18 du tableau périodique
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 29/02 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS] sans effet anti-inflammatoire
A61P 31/14 - Antiviraux pour le traitement des virus ARN
A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV
11.
COMBINATION PRODUCTS CONTAINING DICYCLOPLATIN, PREPARATION AND USE THEREOF
The present invention relates to a combination product comprising dicycloplatin, a use of the combination product in preparing a drug for treating and/or preventing pain, inflammation, or a disease related to a virus, and a method for preparing the combination product.
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 29/02 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS] sans effet anti-inflammatoire
A61P 31/14 - Antiviraux pour le traitement des virus ARN
A61P 31/18 - Antiviraux pour le traitement des virus ARN du HIV
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
30 - Aliments de base, thé, café, pâtisseries et confiseries
32 - Bières; boissons non alcoolisées
Produits et services
Tonics [medicines]; medicines for human purposes; medicinal
drinks; capsules for medicines; pharmaceutical preparations;
chemico-pharmaceutical preparations; pre-filled syringes for
medical purposes; lozenges for pharmaceutical purposes;
crude drugs; traditional Chinese medicines. Urological apparatus and instruments; sprayers for medical
purposes; aerosol masks for medical purposes; apparatus for
use in medical analysis; testing apparatus for medical
purposes; massage apparatus; medical apparatus and
instruments; receptacles for applying medicines;
vibromassage apparatus; fumigation apparatus for medical
purposes. Pastries; condiments; bechamel; leaven; essences for
foodstuffs, except etheric essences and essential oils;
vanilla [flavoring]; vegetal preparations for use as coffee
substitutes; tea; tea-based beverages; natural sweeteners. Non-alcoholic beverages; isotonic beverages; vegetable
beverages.
Beer; Water beverages; Non-alcoholic malt beverages; Non-alcoholic beverages containing fruit juices; Non-alcoholic water-based beverages; Aerated water; Non-alcoholic beverages flavored with tea; Vegetable drink; Preparations for making beverages, namely, fruit drinks; Syrups for beverages; Concentrates and powders used in the preparation of energy drinks and fruit-flavored beverages; Energy drinks; Energy drinks enhanced with vitamins, minerals, nutrients; Isotonic beverages; Isotonic drinks; Isotonic non-alcoholic drinks; Powders used in the preparation of isotonic sports drinks and sports beverages; Protein-enriched sports beverages; Sports drinks; Sports drinks enhanced with vitamins, minerals, nutrients; Sports drinks, namely, energy drinks; Sports drinks, namely, performance drinks; Whey beverages
05 - Produits pharmaceutiques, vétérinaires et hygièniques
32 - Bières; boissons non alcoolisées
Produits et services
Tonics of medicines, namely, medicinal tea; medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in preventing prostatitis, benign prostatic hyperplasia, urinary tract infection, gynecological inflammation, gastrointestinal disease; medicines for human purposes in the form of effervescent tablets, chewable tablet and chewing gum for use in blood sugar regulation, liver protection, and as antioxidants, anti-hyperlipidemia, anti-aging, antineoplastic and antiviral agents for medical use; Medicines for human purposes, namely, medicines for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, rhinitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Medicinal drinks; Capsules sold empty for pharmaceuticals; Pharmaceutical preparations for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; Chemical-pharmaceutical preparations for tumor-suppression and antiviral treatment; Injectable syringes sold filled with vaccines, antivirals and tumor-suppression agents; Troches, namely, tablets for use in tumor-suppression, as antivirals and for the treatment of chronic gastrointestinal disease; Tinctures in the nature of medicinal herb extracts; Tincture of iodine; Tinctures in the nature of antiseptics for use in the treatment of traumatic injuries; Herbs for medicinal purposes; Nutritional supplements; Dietetic foods, namely, dietetic crackers, dietetic sugar for medical use, Dietetic sugar substitutes for medical use; Dietary and nutritional supplements; Dietary food supplements; Dietary supplemental drinks; Dietary supplements; Dietetic beverages adapted for medical use; Dietetic foods adapted for medical purposes; Dietetic foods and beverages adapted for medical use; Nutraceuticals for use as a dietary supplement; Nutritional supplements in the form of capsules, tablets, caplets, powder, syrups, gummies and gels Beer; Water beverages; Non-alcoholic malt beverages; Non-alcoholic beverages containing fruit juices; Non-alcoholic water-based beverages; Aerated water; Non-alcoholic beverages flavored with tea; Vegetable drink; Preparations for making beverages, namely, fruit drinks; Syrups for beverages; Concentrates and powders used in the preparation of energy drinks and fruit-flavored beverages; Energy drinks; Energy drinks enhanced with vitamins, minerals, nutrients; Isotonic beverages; Isotonic drinks; Isotonic non-alcoholic drinks; Powders used in the preparation of isotonic sports drinks and sports beverages; Protein-enriched sports beverages; Sports drinks; Sports drinks enhanced with vitamins, minerals, nutrients; Sports drinks, namely, energy drinks; Sports drinks, namely, performance drinks; Whey beverages
05 - Produits pharmaceutiques, vétérinaires et hygièniques
10 - Appareils et instruments médicaux
30 - Aliments de base, thé, café, pâtisseries et confiseries
32 - Bières; boissons non alcoolisées
Produits et services
Medicinal tonics for the treatment of cancer, prostatitis, benign prostatic hyperplasia, Alzheimer's disease, rheumatoid arthritis, bone injury diseases, thyroid nodules, diabetes, HBV, HIV, fatty liver disease, and alcoholic liver disease; medicines for human purposes for the treatment of cancer, prostatitis, benign prostatic hyperplasia, Alzheimer's disease, rheumatoid arthritis, bone injury diseases, thyroid nodules, diabetes, HBV, HIV, fatty liver disease, and alcoholic liver disease; medicinal drinks; capsules for medicines sold empty; pharmaceutical preparations for the treatment of gastrointestinal disease, skin disease, cardiovascular disease, gout, asthma, nasitis, prostatic cancer, leukemia, melanoma, brain glioma, colon cancer, cervical cancer, thyroid cancer, kidney cancer, stomach cancer and lung cancer, hepatitis B, hepatitis C, AIDS and influenza, prostatitis, benign prostatic hyperplasia and gynecological inflammation, diabetes, sleep disorder and rheumatoid arthritis; chemical-pharmaceutical preparations for the treatment of cancer, prostatitis, benign prostatic hyperplasia, Alzheimer's disease, rheumatoid arthritis, bone injury diseases, thyroid nodules, diabetes, HBV, HIV, fatty liver disease, and alcoholic liver disease; pre-filled syringes for medical purposes for the treatment of cancer, asthma, and insomnia; medicated lozenges for pharmaceutical purposes; traditional Chinese medicines in the nature of medicinal herbs Urological surgical apparatus and instruments; medical sprayers for cleaning gums and teeth used in dentists' offices during dental procedures; aerosol masks for medical purposes; apparatus for use in medical analysis, namely, stethoscopes and X-ray CT scanners; testing apparatus for medical purposes, namely, surgical microscopes and X-ray CT scanners; massage apparatus; medical apparatus and instruments, namely, stethoscopes and X-ray CT scanners; receptacles for applying medicines, namely, insulin injectors sold empty and implantable subcutaneous drug delivery devices sold empty; vibromassage apparatus; fumigation apparatus for medical purposes Pastries; condiments, namely, chutney, minced garlic, and prepared horseradish; béchamel sauce; food leavening agents; food flavorings being non-essential oils; vanilla flavorings for food or beverages; vegetal preparations for use as coffee substitutes; tea; tea-based beverages; natural sweeteners Non-alcoholic beverages, namely, fruit drinks, soda pop, and drinking water; isotonic beverages; vegetable beverages
The present invention relates to a process to prepare dicycloplatin under mild reactive conditions and at fast reaction rates. The process is reproducible and easy to scale up for industrial application.
The present invention relates to a process to prepare dicycloplatin under mild reactive conditions and at fast reaction rates. The process is reproducible and easy to scale up for industrial application.
