The present invention relates inter alia to a hydraulic device which may be used as a hydraulic transformer. The hydraulic device comprising a housing, a first tubular cavity and a second tubular cavity both being provided within the housing. A piston structure is reciprocatable arranged within the housing and comprises a first piston and a second piston; wherein the first piston divides the first cavity into two chambers, and the second piston divides the second cavity into two chambers. Fluid passages for individually exchanging fluid between the chambers and the exterior of the housing are provided and each fluid passage comprising a controllable shut-off valve so as to provide the reciprocating movement of the piston structure by exchanging fluid between exterior and the two chambers of the first cavity, and said hydraulic transformed being configured to control the shut-off valves to selectively be in a closed state or in an open state.
F15B 11/028 - Systems essentially incorporating special features for controlling the speed or the actuating force or speed of an output member for controlling the actuating force
2.
POWER MODULE WITH REDUCED TRIPLE POINT MAXIMUM ELECTRIC FIELD
The present invention provides a power module, especially configured for Medium Voltage (MV) applications. The power module comprises an electrically non- conductive substrate with first and second electrically conductive pads connected to respective external terminals. The first conductive pad is configured for connection to an electric high voltage (HV) potential, such as in the MV range, e.g. 15 kV, and the second conductive pad is configured for connection to electric ground. A semiconductor chip, such as a Silicon Carbide based chip, is directly secured to the first or the second conductive pad. At least a first electrically conductive guard structure is arranged on the upper surface of the non-conductive substrate so as to form a closed ring around the first conductive pad. This first guard structure is configured for electric connection to an electrical potential between electric ground and the HV potential, such as an electric potential of at least 0.5 times the HV potential, such as 0.7-0.9 times the HV potential. Preferred embodiments illustrate how a voltage divider structure can be integrated into the power module to provide the optimal electric potential for the guard structure to give optimal reduction of maximum electric field in the trench.
H01L 23/24 - Fillings characterised by the material, its physical or chemical properties, or its arrangement within the complete device solid or gel, at the normal operating temperature of the device
H01L 23/373 - Cooling facilitated by selection of materials for the device
H01L 23/62 - Protection against overcurrent or overload, e.g. fuses, shunts
H01L 25/07 - Assemblies consisting of a plurality of individual semiconductor or other solid state devices all the devices being of a type provided for in the same subgroup of groups , or in a single subclass of , , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
The present invention relates to compounds of Non-Ribosomal Peptide Synthetase and methods of analysing them. In particular the present invention relates to the use of these compounds in vaccines and antigen-binding molecules targeting these compounds.
The present invention concerns a planar winding assembly for power applications, said assembly comprising a frame accommodating a stack of a plurality of printed circuit boards (PCBs), each comprising at least one conductive winding on the PCB, wherein the stack comprises an uppermost first PCB comprising an electrically insulating layer having a top surface and a bottom surface, where the bottom surface is provided with a conductive winding having a first winding pattern; at least one second PCB comprising an electrically insulating layer having a top surface and a bottom surface with conductive windings thereon, where the top surface is provided with the first winding pattern and the bottom surface is provided with a second winding pattern corresponding to the first winding pattern; a lowermost first PCB, which is similar to the uppermost first PCB but positioned with the winding facing upwards; means for holding the plurality of PCBs tightly against each other in the stacked configuration, and the frame encompasses the stack of PCBs. The invention further concerns a method of manufacturing a planar winding assembly for high-power applications.
H01F 27/30 - Fastening or clamping coils, windings, or parts thereof together; Fastening or mounting coils or windings on core, casing, or other support
5.
INHIBITORY NUCLEIC ACIDS AND METHODS OF USE THEREOF
The present disclosure provides inhibitory nucleic acids, compositions comprising the inhibitory nucleic acids, and methods of using the inhibitory nucleic acids to treat various disorders.
A61K 31/712 - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
A61K 31/7125 - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61P 3/08 - Drugs for disorders of the metabolism for glucose homeostasis
A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
6.
REDUCING PARASITIC CAPACITANCE IN MEDIUM-VOLTAGE INDUCTORS
The present invention relates to inter alia to a conductor having at least two windings where each of the two windings preferably has layered configuration of turns, where each layer of a winding preferably is serially connected. Further, layers are typically distanced from each other, preferably by use of layer spacers, which preferably provide a void, or a number of voids, in between each layers. Conductors according to the present invention have shown to lessen, such as reducing parasitic capacitance.
H01F 27/34 - Special means for preventing or reducing unwanted electric or magnetic effects, e.g. no-load losses, reactive currents, harmonics, oscillations, leakage fields
H01F 1/153 - Amorphous metallic alloys, e.g. glassy metals
H01F 27/00 - MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES - Details of transformers or inductances, in general
H01F 27/32 - Insulating of coils, windings, or parts thereof
INESC TEC - INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES, TECNOLOGIA E CIÊNCIA (Portugal)
UNIVERSIDADE DO PORTO (Portugal)
AALBORG UNIVERSITET (Denmark)
Inventor
Gaudio, Alex
Renna, Francesco
Schmidt, Samuel
Tavares Coimbra, Miguel
Abstract
The present document discloses a computer-implemented method for non-invasive estimation of Pulmonary Hypertension, PH, from heart sound signals, comprising the steps: receiving a sound signal acquired from a beating heart of a subject over a predetermined time period; generating one or more 2D feature maps comprising a 2D feature map with the received sound signal where a first axis of the map is arranged over time and a second axis of the map is arranged over individual heartbeats; applying a pre-trained neural network to relate the generated one or more 2D feature maps with a training dataset of previously acquired and generated training 2D feature maps of a PH subject group and a non-PH subject group, thus to obtain an indicator of the presence of Pulmonary Hypertension. It further discloses a training method of said neural network and a system.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
9.
A PLANNING METHOD FOR PROCESSING AN ELEMENT INTO A FINAL ELEMENT
The present invention relates to a computer-implemented method for planning laser processing of one or more elements into one or more final elements, such as planning a process of creating a final element from a sheet metal by creating a 5 model of both the sheet metal to be processed and the final element and determining a plurality of processing steps to create said final element. The method is based on a plurality of rules for taking into account, how to process the element by a plurality of processing steps, said processing steps comprising laser process specifications and generating at least a first set of instructions for an 10 associated laser processing device.
G05B 19/4097 - Numerical control (NC), i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by using design data to control NC machines, e.g. CAD/CAM
10.
A DEVICE AND A METHOD FOR SENSING VIBRATIONS IN A HUMAN'S SKIN EMANATING FROM BLOOD FLOW BELOW THE SKIN
The present invention relates to a device (1) and a method for sensing vibrations in a human's skin (2) emanating from blood flowing in a natural or artificial blood vessel or an arteriovenous fistula (AVF) (3) located below the skin. The device comprises a sensor (4), a controller (5), a transmitter (6), and an electrical power source (7). In particular, the invention relates to such a device that is configured to be fastened to the human and carried around by the human during use of the device. The measured signals are analysed, and if the blood flow is below a pre- selected blood flow threshold, an alarm signal is issued to warn e.g. a responsible medical doctor that there is a need for further assessment.
A61B 5/0295 - Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
11.
METHOD OF MANUFACTURING A FIBRE REINFORCED COMPOSITE COMPONENT HAVING A REINFORCED HOLE
The invention relates to a method of manufacturing a composite component with continuous fibre reinforcement and having a reinforced hole. The hole is reinforced by incorporation of at least one reinforcing element (1) into a layered arrangement of continuous fibres. The reinforcing element comprises a circumferential member (2) with a through-going first hole (9) and a plurality of continuous element fibres (3). The at least one reinforcing element (1) is arranged in an overlapping and/or sandwiching engagement with the layered arrangement so that the first hole is arranged within and aligned with a second hole (8) to be reinforced. Hereby an externally force applied to the reinforced hole during use of the component is distributed over a larger region of the material around the hole. Thereby the component can be joined to another part e.g. by a bolted connection which allows for disassembly that would not have been possible if they were joined by adhesive joining.
B29C 70/68 - Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts by incorporating or moulding on preformed parts, e.g. inserts or layers
The invention relates to a screw pile (100) adapted for being installed in the ground for providing foundation for a construction (800) or a like, said screw pile comprising an elongated body (200), wherein at least one of the upper part (210), middle part (220) or lower part (230) of the elongated body comprises one or more threaded portions (300), and wherein at least a portion of the volume of the screw pile is concrete (400), said portion of concrete being 50% or more of the volume of the screw pile. In some embodiments, only the lower part of the screw pile has a threaded portion and is made of metal, while an elongated shaft is made of at least 70% concrete. Furthermore, the invention relates to a method of manufacturing a screw pile, said method comprising at least the steps of: providing a mold (600), providing a wet concrete mixture (700) in a liquid form, optionally, providing reinforcement (500), preferably being bars, wires or spirals, optionally, inserting the reinforcement into the concrete mixture, filling the mold with the concrete mixture.
The present invention relates to a method for installation and validation of a screw pile (100) being installed in the ground, said method comprising the steps of: placing at least one screw pile at a location, providing means for screwing (200) the at least one screw pile into the ground, starting screwing the at least one screw pile into the ground by the means for screwing, during the process of screwing measuring at least a set of installation parameters comprising: torsion and/or torque and penetration depth, generating an output indicative of said installation parameters, and providing an installation validation, e.g. an installation validation document or file, of the at least one screw pile. In some embodiments the method comprises to stop screwing the screw pile into the ground when predetermined thresholds of installation parameters are reached. In some embodiments the method comprises generating a data on how the screw pile was installed, e.g. screw direction and rotation versus penetration depth data, e.g. to be included as part of the installation validation. Furthermore, the present invention relates to an installation validation document for at least one screw pile installed in the ground, moreover the invention relates to a computer program.
The present invention provides a power module arranged to receive a DC electric input signal at first and second connection terminals (A, B), and to output an AC electric output signal at third and fourth connection terminals (C, D). A set of capacitors (CAP1, CAP2) are connected between respective sets of connection terminals (A, B, C, D). Two inductors (L1, L2) are connected at least to respective connection terminals (C, D), such as the first inductor (L1) being connected between on set of connection terminals (A, C), and the second inductor (L2) being connected between another set of connection terminals (B, D). A switch network (SWN) with at least one electrically controllable bidirectional two-quadrant switch (s1), is connected between at least two of the four connection terminals (A, B, C, D). The at least one witch (s1) is arranged for being controlled according to a switching cycle, so as to provide an average voltage (V1) of zero across the first inductor (L1) over one switching period of the switching cycle, and to provide an average voltage (V2) of zero across the second inductor (L2) over one switching period. The power module is simple, and can be implemented with only one single switch per module. A DC to AC power converter can be build of a number of interconnected power modules, and such power converter can be designed to provide an AC output voltage in the kV range at a power in the kW range, at a frequency of up to such as 40 MHz.
H02M 1/00 - APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC, OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWER SUPPLY SYSTEMS; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUT POWER; CONTROL OR REGULATION THEREOF - Details of apparatus for conversion
H02M 7/48 - Conversion of dc power input into ac power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode
H02M 7/49 - Combination of the output voltage waveforms of a plurality of converters
H02M 7/483 - Converters with outputs that each can have more than two voltage levels
H02M 3/335 - Conversion of dc power input into dc power output with intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate ac using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
15.
APPARATUS AND METHOD FOR TESTING THE LOAD BEARING CAPACITY OF A FOUNDATION PILE
The invention relates to a load-bearing test apparatus adapted to test the load-bearing capacity of an associated pile installed in the ground, preferably an associated screw pile, the load-bearing test apparatus comprising: a load carrier having at least one main protrusion and at least one receiving portion, a load being positioned on the load carrier or being an integrated part of the carrier, preferably being a plurality of load plates, a shaft adapted for allowing the load carrier to slide up and down in a vertical direction, at least one connecting piece for attachable connecting the load carrier to the associated pile, and a locking system. Furthermore, the invention relates to a method for testing the load-bearing capacity of a pile installed in the ground.
The present invention relates to method for cutting and shaping and/or bending a metal element into a final element using laser means, the method comprising providing data containing a final model of the final element and providing a set of instructions as to how to process the final element from the metal element, measure the processing and provide at least a second set of instructions based on feedback, such as geometrical measurements during said processing, so as to create a final element.
G05B 19/18 - Numerical control (NC), i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form
17.
METHOD FOR CONTROLLING AN ORTHOPEDIC DEVICE AND ORTHOPEDIC DEVICE
The invention deals with a method for controlling an orthopedic device, the method comprising the following steps of: —Providing input signals, —Using said input signals as input variables of a musculoskeletal model, —Determining feedback signals using said musculoskeletal model, —Transmitting said feedback signals to said user of said orthopedic device.
Disclosed is an energy harvester for generating electric energy from an external vibratory force, such as a vibratory force caused by movement of a part of a living human or animal. The energy harvester has a compartment (CMP1, CMP2) with wall element(s) forming a cavity inside. At least one wall element of the compartment has a piezoelectric element connected to an electric output terminal. An impact object (BL) is positioned inside the cavity of the compartment. The impact object is configured to move inside the cavity and to generate an impact on a surface of the wall element(s), so as to cause the piezoelectric element to generate an electric output on the electric output terminal. The compartment may have a cubic shape, e.g. made of a single piezoelectric element folded into shape, e.g. a two-layer piezoelectric element. The impact object may be a metal or ceramics object with a spherical shape. Especially, the energy harvester may be used to power an implantable medical device, e.g. an intra-cardiac pacemaker. An energy harvester housing within an intra-cardiac pacemaker has been tested to be sufficient for powering the pacemaker stimulation circuit by the vibratory force caused by heartbeats.
H02N 2/18 - Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing electrical output from mechanical input, e.g. generators
The present invention relates to glass-based substrates and articles that can be hydrated under special circumstances to increase their crack resistance and induce self-healing, and to processes for their production.
C03C 3/083 - Glass compositions containing silica with 40% to 90% silica by weight containing aluminium oxide or an iron compound
C03C 3/085 - Glass compositions containing silica with 40% to 90% silica by weight containing aluminium oxide or an iron compound containing an oxide of a divalent metal
C03C 3/091 - Glass compositions containing silica with 40% to 90% silica by weight containing boron containing aluminium
C03C 23/00 - Other surface treatment of glass not in the form of fibres or filaments
C03C 21/00 - Treatment of glass, not in the form of fibres or filaments, by diffusing ions or metals into the surface
The present invention relates inter alia to a hydraulic device which may be used as a hydraulic transformer. The hydraulic device comprising a housing, a first tubular cavity and a second tubular cavity both being provided within the housing. A piston structure is reciprocatable arranged within the housing and comprises a first piston and a second piston; wherein the first piston divides the first cavity into two chambers, and the second piston divides the second cavity into two chambers. Fluid passages for individually exchanging fluid between the chambers and the exterior of the housing are provided and each fluid passage comprising a controllable shut-off valve so as to provide the reciprocating movement of the piston structure by exchanging fluid between exterior and the two chambers of the first cavity, and said hydraulic transformed being configured to control the shut-off valves to selectively be in a closed state or in an open state.
F15B 3/00 - Intensifiers or fluid-pressure converters, e.g. pressure exchangers; Conveying pressure from one fluid system to another, without contact between the fluids
F15B 11/032 - Systems essentially incorporating special features for controlling the speed or the actuating force or speed of an output member for controlling the actuating force by means of fluid-pressure converters
F15B 11/036 - Systems essentially incorporating special features for controlling the speed or the actuating force or speed of an output member for controlling the actuating force by means of servomotors having a plurality of working chambers
21.
Non-invasive front-end for power electronic monitoring
A front-end device for monitoring operation of an associated electric power device with semiconductor power switches generating a power output, e.g. a three-phase power output. The front-end device has input terminals arranged for connection to the electric phase(s) of the power output of the associated electric power device, and an electric circuit connected to the input terminals and connected to at set of output terminals. The electric circuit has a passive interconnection comprising electric semiconductor switches and diodes. The electric circuit serves to electrically block any high voltage component from the input terminals from reaching the output terminals, while allowing an on-state voltage of at least one semiconductor power switch in the associated electric power device to pass to the at least two output terminals. The front-end allows low voltage equipment to be connected to its output terminals for determining an on-state voltage of switches of the electric power device. Especially, embodiments with self-powered reference voltage circuits provided by zener diodes allow compact low cost versions for use in e.g. portable test equipment or as part of permanently installed health condition monitoring of power devices. The front-end device can be used as a simple and low cost solution for non-invasive health condition monitoring of power devices, e.g. power converters in such as power electric generation system or electric vehicles. Such monitoring allows predictive maintenance to be performed to avoid any faults in the power device that may cause permanent damages.
The invention provides a non-invasive tongue based with a tongue sensor device arranged for position in the oral cavity of the user. A sensor panel to be placed on an upper part of the oral cavity of the user, and having a 2D array of activation zones and related electric coils. A guide structure, e.g. a metal or polymer frame, carries a ferrous or metallic activation unit movably in a plane upon manipulation by the user's tongue. This allows the user to position the activation unit in relation the activation zones. The guide structure allows the activation unit to move also perpendicular to the plane, to allow the user's tongue to manipulate the activation unit near one activation zone for activation of the activation zone. An electronic circuit inductively senses activation of any one or more of the plurality of activation zones and related electric coils and generates an output accordingly, e.g. a wireless RF output. E.g. a frame structure of metal wires or bars can be used to implement the guide structure, thus allowing the activation unit, e.g. a metal sphere or cylinder, to form an integrated part of the rather than being mounted in an invasive way on the user's tongue.
The present invention provides antisense oligonucleotides directed against immune checkpoints and methods and compositions of using such antisense oligonucleotides for the treatment of cancer.
The invention relates to a hand orthosis (1) for assisting the movements of a user's hand. The hand orthosis comprises a soft glove (2) adapted to receive at least a part of the user's hand with finger sections of the glove receiving each of the user's fingers. It further comprises at least one actuator box (3), and a power transmission (4) for transferring forces from the at least one actuator box to different parts of the glove via exo-tendons (5). The exo-tendons are arranged on a dorsal side, on a palmar side, or on both a dorsal side and a palmar side of the glove. The exo-tendons are arranged so that the glove can assist flexion, extension, or both extension and flexion of the fingers, respectively and so that the exo-tendons act on the fingers to produce motion that mimics the movement of a human hand. The hand orthosis provides different grasp types, self- adaptation of the fingers' motion to the shape of the object, and physiologically appropriate distribution of finger forces.
A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
25.
REDUCING PARASITIC CAPACITANCE IN MEDIUM-VOLTAGE INDUCTORS
The present invention relates to inter alia to a conductor having at least two windings where each of the two windings preferably has layered configuration of turns, where each layer of a winding preferably is serially connected. Further, layers are typically distanced from each other, preferably by use of layer spacers, which preferably provide a void, or a number of voids, in between each layers. Conductors according to the present invention have shown to lessen, such as reducing parasitic capacitance.
The proposed technology relates to the quantifying of cardiorespiratory fitness. It includes the obtaining (102) of a seismocardiogram (SCG) recorded with an accelerometer (14) configured to measure accelerations and vibrations of the chest wall of a person (18) caused by myocardial movement. Properties of a first signal feature (AC) in the seismocardiogram (SCG) are determined (104), wherein the first signal feature (AC) corresponds to the aortic valve closure (AC) of a heartbeat. A measure indicating cardiorespiratory fitness (VO2 max) is then determined (106) based on the properties of first signal feature (AC).
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
Region Nordjylland, Aalborg University Hospital (Denmark)
Aarhus Universitet (Denmark)
Aalborg Universitet (Denmark)
Inventor
Gade, Inger Lise
Honoré, Bent
Kristensen, Søren Risom
Abstract
A method is provided for determining pulmonary embolism and/or increased risk thereof in a human being, comprising collecting a sample of exhalation air from said human being and determining the presence or absence in said exhaled air of one or more biomarkers associated with pulmonary embolism. Additionally, a kit that comprises the means for detecting at least one biomarker associated with pulmonary embolism or risk thereof is provided.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
A61K 31/7115 - Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
29.
Identification and Quantification of A Ventilatory Disturbance Causing Incorrect Measurement Of Arterial Acid-Base Status
The present invention relates to a computer-implemented method for identification of the degree to which a transient disturbance in ventilation causes changes in measurement of arterial acid-base status.
The invention relates to a curved spherical scissors linkage mechanism (1) comprising at least four linkage elements (2) each having a first end (3) and a second end (4); the linkage elements are arranged to form sides of one rhombus or parallelogram, or a series, such as a network, of joined rhombi or parallelograms. Each of the linkage elements is rotationally connected to one of the other linkage elements via a revolute joint (5) at or near the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at or near the second end. The linkage elements are shaped, dimensioned and arranged so that the axes of all the revolute joints coincide at one common remote centre of motion (RCM). Furthermore, the mechanism is grounded or connected or connectable to a first external member (7) at a proximal end and is rotationally connected or connectable to a second external member (9) at an opposite distal end. Hereby a spherical linkage mechanism with three DOFs is obtained. The spherical scissors linkage mechanism may further comprise a motion controlling mechanism at the proximal and/or at the distal end. It further comprises actuator means as control means.
The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
32.
METHOD OF MANUFACTURING A FIBRE REINFORCED COMPOSITE COMPONENT HAVING A REINFORCED HOLE
The invention relates to a method of manufacturing a composite component with continuous fibre reinforcement and having a reinforced hole. The hole is reinforced by incorporation of at least one reinforcing element (1) into a layered arrangement of continuous fibres. The reinforcing element comprises a circumferential member (2) with a through-going first hole (9) and a plurality of continuous element fibres (3). The at least one reinforcing element (1) is arranged in an overlapping and/or sandwiching engagement with the layered arrangement so that the first hole is arranged within and aligned with a second hole (8) to be reinforced. Hereby an externally force applied to the reinforced hole during use of the component is distributed over a larger region of the material around the hole. Thereby the component can be joined to another part e.g. by a bolted connection which allows for disassembly that would not have been possible if they were joined by adhesive joining.
B29C 70/20 - Fibrous reinforcements only characterised by the structure of fibrous reinforcements using fibres of substantial or continuous length oriented in a single direction, e.g. roving or other parallel fibres
B29C 70/30 - Shaping by lay-up, i.e. applying fibres, tape or broadsheet on a mould, former or core; Shaping by spray-up, i.e. spraying of fibres on a mould, former or core
B29C 70/76 - Moulding on edges or extremities of the preformed part
B29C 70/84 - Moulding material on preformed parts to be joined
B29C 70/86 - Incorporating in coherent impregnated reinforcing layers
B29C 70/32 - Shaping by lay-up, i.e. applying fibres, tape or broadsheet on a mould, former or core; Shaping by spray-up, i.e. spraying of fibres on a mould, former or core on a rotating mould, former or core
B29C 70/38 - Automated lay-up, e.g. using robots, laying filaments according to predetermined patterns
The invention deals with a method for controlling an orthopedic device, the method comprising the following steps of: - Providing input signals, - Using said input signals as input variables of a musculoskeletal model, - Determining feedback signals using said musculoskeletal model, - Transmitting said feedback signals to said user of said orthopedic device.
The present invention relates to method for cutting and shaping and/or bending a metal element into a final element using laser means, the method comprising providing data containing a final model of the final element and providing a set of instructions as to how to process the final element from the metal element, measure the processing and provide at least a second set of instructions based on feedback, such as geometrical measurements during said processing, so as to create a final element.
G05B 19/4097 - Numerical control (NC), i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by using design data to control NC machines, e.g. CAD/CAM
36.
A PLANNING METHOD FOR PROCESSING AN ELEMENT INTO A FINAL ELEMENT
The present invention relates to a computer-implemented method for planning laser processing of one or more elements into one or more final elements, such as planning a process of creating a final element from a sheet metal by creating a 5 model of both the sheet metal to be processed and the final element and determining a plurality of processing steps to create said final element. The method is based on a plurality of rules for taking into account, how to process the element by a plurality of processing steps, said processing steps comprising laser process specifications and generating at least a first set of instructions for an 10 associated laser processing device.
G05B 19/4097 - Numerical control (NC), i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by using design data to control NC machines, e.g. CAD/CAM
37.
NON-INVASIVE FRONT-END FOR POWER ELECTRONIC MONITORING
A front-end device for monitoring operation of an associated electric power device with semiconductor power switches generating a power output, e.g. a three-phase power output. The front-end device has input terminals arranged for connection to the electric phase(s) of the power output of the associated electric power device, and an electric circuit connected to the input terminals and connected to at set of output terminals. The electric circuit has a passive interconnection comprising electric semiconductor switches and diodes. The electric circuit serves to electrically block any high voltage component from the input terminals from reaching the output terminals, while allowing an on-state voltage of at least one semiconductor power switch in the associated electric power device to pass to the at least two output terminals. The front-end allows low voltage equipment to be connected to its output terminals for determining an on-state voltage of switches of the electric power device. Especially, embodiments with self-powered reference voltage circuits provided by zener diodes allow compact low cost versions for use in e.g. portable test equipment or as part of permanently installed health condition monitoring of power devices. The front-end device can be used as a simple and low cost solution for non-invasive health condition monitoring of power devices, e.g. power converters in such as power electric generation system or electric vehicles. Such monitoring allows predictive maintenance to be performed to avoid any faults in the power device that may cause permanent damages.
Existing modular multi-level converters can be bulky because their submodule capacitors are comparatively large. To address this shortcoming in the state of the art, the present disclosure provides electronic power circuits and their use in power converters and in modular multi-level converters. The disclosed power circuits include connection terminals connected to electrically controllable bidirectional two-quadrant switches and to capacitors, as well as inductors that are magnetically coupled and operate to equalize voltages of the capacitors.
H02M 7/483 - Converters with outputs that each can have more than two voltage levels
H02M 3/335 - Conversion of dc power input into dc power output with intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate ac using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
An active two-terminal inductor device with a controllable inducitance based on an inductance value input L_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value inductor component L1. Based on sampling of at least a voltage or a current in connection with the inductor component L1, the algorithm controls the power converter PCV to provide a resulting inductance across the external terminals A, B which serves to match the inductance value input L_I.
H01F 7/06 - Electromagnets; Actuators including electromagnets
H01F 7/20 - Electromagnets; Actuators including electromagnets without armatures
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
The invention relates to a hand orthosis (1) for assisting the movements of a user's hand. The hand orthosis comprises a soft glove (2) adapted to receive at least a part of the user's hand with finger sections of the glove receiving each of the user's fingers. It further comprises at least one actuator box (3), and a power transmission (4) for transferring forces from the at least one actuator box to different parts of the glove via exo-tendons (5). The exo-tendons are arranged on a dorsal side, on a palmar side, or on both a dorsal side and a palmar side of the glove. The exo-tendons are arranged so that the glove can assist flexion, extension, or both extension and flexion of the fingers, respectively and so that the exo-tendons act on the fingers to produce motion that mimics the movement of a human hand. The hand orthosis provides different grasp types, self- adaptation of the fingers' motion to the shape of the object, and physiologically appropriate distribution of finger forces.
A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
An active two-terminal capacitor device with a controllable capacitance based on a capacitance value input C_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value capacitor component CI. Based on sampling of at least the voltage across the capacitor component CI, the algorithm controls the power converter PCV to provide a resulting capacitance across the external terminals A, B which serves to match the capacitance value in ut C_I.
H02M 3/158 - Conversion of dc power input into dc power output without intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load
G06F 1/26 - Power supply means, e.g. regulation thereof
H02M 7/00 - Conversion of ac power input into dc power output; Conversion of dc power input into ac power output
H02M 7/5387 - Conversion of dc power input into ac power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only, e.g. single switched pulse inverters in a bridge configuration
43.
MULTIPARAMETERIC ESTIMATION OF CARDIORESPIRATORY FITNESS IN SEISMOCARDIOGRAPHY
The proposed technology relates to the quantifying of cardiorespiratory fitness. It includes the obtaining (102) of a seismocardiogram (SCG) recorded with an accelerometer (14) configured to measure accelerations and vibrations of the chest wall of a person (18) caused by myocardial movement. Properties of a first signal feature (AC) in the seismocardiogram (SCG) are determined (104), wherein the first signal feature (AC) corresponds to the aortic valve closure (AC) of a heartbeat. A measure indicating cardiorespiratory fitness (VO2max) is then determined (106) based on the properties of first signal feature (AC).
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61B 5/0205 - Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
44.
BIOMARKERS FOR PULMONARY EMBOLISM IN EXHALED BREATH CONDENSATE
REGION NORDJYLLAND, AALBORG UNIVERSITY HOSPITAL (Denmark)
AARHUS UNIVERSITET (Denmark)
AALBORG UNIVERSITET (Denmark)
Inventor
Gade, Inger, Lise
Honoré, Bent
Kristensen, Søren, Risom
Abstract
A method is provided for determining pulmonary embolism and/or increased risk thereof in a human being, comprising collecting a sample of exhalation air from said human being and determining the presence or absence in said exhaled air of one or more biomarkers associated with pulmonary embolism. Additionally, a kit that comprises the means for detecting at least one biomarker associated with pulmonary embolism or risk thereof is provided.
The proposed technology relates to the quantifying of cardiorespiratory fitness. It includes the obtaining (102) of a seismocardiogram (SCG) recorded with an accelerometer (14) configured to measure accelerations and vibrations of the chest wall of a person (18) caused by myocardial movement. Properties of a first signal feature (AC) in the seismocardiogram (SCG) are determined (104), wherein the first signal feature (AC) corresponds to the aortic valve closure (AC) of a heartbeat. A measure indicating cardiorespiratory fitness (VO2max) is then determined (106) based on the properties of first signal feature (AC).
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
46.
Therapeutic targeting of a microRNA to treat Duchenne muscular dystrophy
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
A61K 31/7115 - Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
47.
SPHERICAL MECHANISM CONSTRUCTED WITH SCISSORS LINKAGES WITH CONTROL MEANS
The invention relates to a curved spherical scissors linkage mechanism (1) comprising at least four linkage elements (2) each having a first end (3) and a second end (4); the linkage elements are arranged to form sides of one rhombus or parallelogram, or a series, such as a network, of joined rhombus or parallelograms. Each of the linkage elements is rotationally connected to one of the other linkage elements via a revolute joint (5) at or near the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at or near the second end. The linkage elements are shaped, dimensioned and arranged so that the axes of all the revolute joints coincide at one common remote centre of motion (RCM). Furthermore, the mechanism is grounded or connected or connectable to a first external member (7) at a proximal end and is rotationally connected or connectable to a second external member (9) at an opposite distal end. Hereby a spherical linkage mechanism with three DOFs is obtained. The spherical scissors linkage mechanism may further comprise a motion controlling mechanism at the proximal and/or at the distal end. It further comprises actuator means as control means.
The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.
The present invention relates to a computer-implemented method for identification of the degree to which a transient disturbance in ventilation causes changes in measurement of arterial acid-base status.
A curved scissor linkage mechanism (1) includes at least four linkage elements (2) each having a first end (3) and a second end (4). The linkage elements are arranged to form sides of one or more rhombi or parallelograms. Each linkage element is rotationally connected to another linkage elements via a revolute joint (5) at the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at the second end. The linkage elements are configured so that the axes of each joint coincide at one common remote centre of motion. The mechanism is connectable to a first external member (7) at a proximal end and is rotationally connectable to a second external member (9) at an opposite distal end to obtain three DOFs. The scissor linkage mechanism may further include a motion controlling mechanism.
F16H 21/54 - Gearings comprising primarily only links or levers, with or without slides with movements in three dimensions for conveying or interconverting oscillating or reciprocating motions
51.
A RECONFIGURABLE COMPLIANT REVOLUTE JOINT MECHANISM WITH NONLINEAR STIFFNESS
The invention is a new design of a compliant revolute joint mechanism, which has multiple configurations exhibiting variable stiffness performance. The joint mechanism provides compliance between its input and output shafts. Variable stiffness performance, such as soft spring, hard spring, in addition to linear spring, can be achieved by changing the mechanism configuration which is based on the wrapping pattern of elastic material, replacing the elastic material of different stiffness, or tuning their pretention force. The invention is designed with a compact structure. The new joint can be integrated into electric motors to build compliant actuators in assistive exoskeletons, rehabilitation robots and other robots where a safe human-robot interaction is concerned. The innovation can also be applied as a new coupling device, which is commonly used in motion transmissions.
F16D 3/62 - Yielding couplings, i.e. with means permitting movement between the connected parts during the drive with the coupling parts connected by one or more intermediate members comprising pushing or pulling links attached to both parts the links or their attachments being elastic
52.
Integrated end-fire MM-wave antenna array with low frequency metal-framed antenna
The present subject matter relates to antenna systems, devices, and methods that are designed to avoid the degradation of the end-fire radiation pattern of the array when a piece of metal is added obstructing the direction of the main beam. A parasitic radiator is positioned in proximity to the blocking structure and configured to couple at least part of the reflected radiation pattern and radiate toward the desired end-fire direction.
H01Q 21/29 - Combinations of different interacting antenna units for giving a desired directional characteristic
H04B 7/06 - Diversity systems; Multi-antenna systems, i.e. transmission or reception using multiple antennas using two or more spaced independent antennas at the transmitting station
H01Q 1/24 - Supports; Mounting means by structural association with other equipment or articles with receiving set
H01Q 1/36 - Structural form of radiating elements, e.g. cone, spiral, umbrella
H01Q 5/392 - Combination of fed elements with parasitic elements the parasitic elements having dual-band or multi-band characteristics
H01Q 7/00 - Loop antennas with a substantially uniform current distribution around the loop and having a directional radiation pattern in a plane perpendicular to the plane of the loop
An electric converter for converting AC or DC input into an electric AC or DC output. A swap circuit with controllable electric switches serves to selectively swap connection of a plurality of DC power banks (DCBs) between an input terminal and an output terminal, thus selectively connecting the DCBs to an electric source or an electric load. The DCBs are formed as series of interconnected submodules (SMs) each having one or more electric energy storage elements (ESEs) and a switching circuit for selectively by-passing or connecting the ESEs. The ESEs can be capacitors, batteries, super capacitors, or a combination of these. By properly controlling the swap circuit and the switching of the SMs, such as by taking into account the dead-time for the electric switches involved, the converter can be used for DC-AC, DC-DC, AC-DC, or AC-AC conversion, allowing multilevel output. It can in some embodiments eliminate the need for an unfolding converter, and the converter provides a rather simple and efficient topology, suitable e.g. for connection of a DC input from a photovoltaic elements to an AC electric grid.
H02M 3/07 - Conversion of dc power input into dc power output without intermediate conversion into ac by static converters using resistors or capacitors, e.g. potential divider using capacitors charged and discharged alternately by semiconductor devices with control electrode
H02M 7/483 - Converters with outputs that each can have more than two voltage levels
H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers
Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
55.
Method and system for measuring the laxity of a joint of a human or an animal
The invention relates to a method of determining the laxity of a joint (9, 15) of a human (5) or an animal. The method comprises providing at least one patient-specific geometrical model (1) of at least one bone and/or at least one prosthesis comprised by the joint. Known loads are applied to the joint or to a part of the body connected to the joint, and a series of actual images (16) of the joint are obtained while the loads are applied. Then the at least one patient-specific geometrical model (1) is registered onto the actual images (16). Based thereon relative displacement and/or rotation of the at least one bone and/or at least one prosthesis is calculated as a function of the applied loads, and based thereon a measure of the laxity of the joint is determined. The invention further relates to a system for performing such a method and to a computer readable medium for performing such a method.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
The present invention relates to electronic power circuits and their use in power converters and in modular multi-level converters (MMCs) comprising such power converters.
H02M 7/483 - Converters with outputs that each can have more than two voltage levels
H02M 3/335 - Conversion of dc power input into dc power output with intermediate conversion into ac by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate ac using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
The invention relates to a method of controlling thermal stress of a semiconductor chip, the method comprises the steps of: establishing a modular frequency of the semiconductor chip and thereby a thermal profile of the semiconductor chip and establishing a pulsing current controlling the thermal profile of a thermoelectric cooling device thermally connected to the semiconductor chip. Wherein the pulsing current is generated in response to the modular frequency, so that a super cooling period of the thermal profile of the thermoelectric cooling device is at least partly overlapping a temperature increasing period of the thermal profile of the semiconductor chip,anda recovery period of the thermal profile of the thermoelectric cooling device is at least partly overlapping a temperature decreasing period of the thermal profile of the semiconductor chip.
H01L 23/38 - Cooling arrangements using the Peltier effect
H01L 35/30 - SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR - Details thereof operating with Peltier or Seebeck effect only characterised by the heat-exchanging means at the junction
H01L 35/32 - SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICES NOT OTHERWISE PROVIDED FOR - Details thereof operating with Peltier or Seebeck effect only characterised by the structure or configuration of the cell or thermocouple forming the device
58.
GENERATING SOUND ZONES USING VARIABLE SPAN FILTERS
The invention provides a method for generating output filters to a plurality of loudspeakers at respective positions for playback of a plurality of different input signals in respective spatially different sound zones by means of a processor system. The method comprising computing spatio-temporal correlation matrices in response to spatial information, e.g. measured transfer functions, and in response to desired sound pressures in the plurality of sound zones. Joint eigenvalue decomposition of the spatial correlation matrices are then computed, or at least an approximation thereof, to arrive at eigenvectors accordingly. Next, variable span filters a reformed from a linear combination of the eigenvectors in response to a desired trade-off between acoustic contrast and acoustic errors in the sound zones. Finally, output filter for each of the plurality of loudspeakers,for each of the plurality of input signals, in accordance with the variable span filters.The method is applicable also for optimization in one zone, e.g. for room equalization.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
A61K 31/7115 - Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
An active two-terminal inductor device with a controllable inducitance based on an inductance value input L_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value inductor component L1. Based on sampling of at least a voltage or a current in connection with the inductor component L1, the algorithm controls the power converter PCV to provide a resulting inductance across the external terminals A, B which serves to match the inductance value input L_I.
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
An active two-terminal capacitor device with a controllable capacitance based on a capacitance value input C_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value capacitor component CI. Based on sampling of at least the voltage across the capacitor component CI, the algorithm controls the power converter PCV to provide a resulting capacitance across the external terminals A, B which serves to match the capacitance value in ut C_I.
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
64.
Method and device for analyzing a condition of a heart
A method for analyzing a condition of a heart, comprises receiving a plurality of electric signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/712 - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/7125 - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
A61P 35/02 - Antineoplastic agents specific for leukemia
The present invention relates to an air-cooled fuel cell assembly (9) comprising a fuel cell (1) having a membrane electrode assembly disposed between an anode fluid flow plate and a cathode fluid flow plate, said cathode flow plate defining a flow channel for conveying oxidant to the membrane electrode assembly, said flow channel having an inlet and an outlet and said flow channel extending between two opposing perimeters (5a, 5b) of said fuel cell assembly (9), an air pump (2) arranged to generate air flow in said flow channel in a first direction (8), a turbulence inducing device (4) upstream, relative to said first direction (8), of said flow channel, said turbulence inducing device comprising a grid.
A technology for quantifying, or determining an indication of, cardiorespiratory fitness is disclosed. A signal portion is obtained from a signal recorded with an accelerometer placed on the chest of a person. The accelerometer measures accelerations and vibrations of the chest wall of the person caused by myocardial movement. A maximum value is determined in the signal portion, and output information is provided indicating cardiorespiratory fitness based on the maximum value.
The invention relates to a curved scissor linkage mechanism(1)comprising at least four linkage elements(2)each having a first end (3) and a second end(4); the linkage elements are arranged to form sides of one rhombus or parallelogram, or a series, such as a network, of joined rhombi or parallelograms. Each of the linkage elements is rotationally connected to one of the other linkage elements via a revolute joint (5) at or near the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at or near the second end. The linkage elements are shaped, dimensioned and arranged so that the axes of all the revolute joints coincide at one common remote centre of motion(RCM). Furthermore, the mechanism is grounded or connected or connectable to a first external member (7) at a proximal end and is rotationally connected or connectable to a second external member (9) at an opposite distal end. Hereby a spherical linkage mechanism with three DOFs is obtained. The scissor linkage mechanism may further comprise a motion controlling mechanism at the proximal and/or at the distal end.
Disclosed apparatus and method improve the computational efficiency of encoding and decoding data having erasures according to a maximum distance separable (MDS) code based on a Reed-Solomon code. Thus, n encoded fragments are formed by multiplying k data fragments by an n×k generator matrix for the MDS code. The code is formed by reducing, in the generator matrix to the extent possible, the size of the finite field to which entries belong—in some cases to the base field having only two elements. In this way, unlike codes known in the art, the generator matrix has more than one column whose entries each take values in the finite field having two elements. In some cases, the generator matrix has a column whose entries each take values in one or more intermediate fields between the finite field having two elements and the encoding field.
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correction; Coding theory basic assumptions; Coding bounds; Error probability evaluation methods; Channel models; Simulation or testing of codes
H03M 13/37 - Decoding methods or techniques, not specific to the particular type of coding provided for in groups
G06F 9/30 - Arrangements for executing machine instructions, e.g. instruction decode
H03M 13/15 - Cyclic codes, i.e. cyclic shifts of codewords produce other codewords, e.g. codes defined by a generator polynomial, Bose-Chaudhuri-Hocquenghem [BCH] codes
G06F 7/72 - Methods or arrangements for performing computations using a digital non-denominational number representation, i.e. number representation without radix; Computing devices using combinations of denominational and non-denominational quantity representations using residue arithmetic
70.
Method and apparatus to enhance routing protocols in wireless mesh networks
A protocol for use in wireless mesh networks uses helper nodes to improve data flow in the network. The protocol is compatible with traditional mesh network routing algorithms. Techniques, systems, devices, and circuits for implementing the protocol are described.
The present invention relates to a method for extracting cannabinoids from cannabis plant material using an extractor with super critical carbon dioxide. The process comprises the steps of: a) providing a cannabis plant material with a water content of at most 60% w/w, preferably at most 10% w/w; b1) in a pressure tank, subjecting the cannabis plant material to a first extraction step with a one-phase solvent system comprising supercritical carbon dioxide and optionally a non-polar co-solvent, and performed at a temperature of about 30-60 degrees Celsius; c1) collecting a first liquid extract from the pressure tank; d) collecting/removing a solid product from the pressure tank comprising a cannabis plant fiber material with a reduced content of cannabinoids; e) dissolving the first liquid extract from the pressure tank in ethanol, subjecting the solution to one or more winterization steps, filtrating the solution to remove precipitated matter, and removing the ethanol to collect a second liquid extract; f) optionally, heat treating the second liquid extract at 100-150 degrees Celsius to decarboxylate any acid form of the cannabinoids to the neutral form of the cannabinoids; g) dissolving the second liquid extract, optionally heat treated, in a non-polar solvent; h) extracting the solubilized second liquid extract with an aqueous basic solution; and collecting the non-polar solvent phase as a third liquid extract; and i) optionally, removing the non-polar solvent to collect the neutral form of the cannabinoids.
The invention relates to a method of diagnosing a migraine and/or migraine attack, the method in a subject comprising determining a change in the expression level of a biological marker in the biological sample. Preferably, the method is the in vitro method.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
73.
METHOD AND SYSTEM FOR MEASURING THE LAXITY OF A JOINT OF A HUMAN OR AN ANIMAL
The invention relates to a method of determining the laxity of a joint (9, 15) of a human (5) or an animal. The method comprises providing at least one patient-specific geometrical model (1) of at least one bone and/or at least one prosthesis comprised by the joint. Known loads are applied to the joint or to a part of the body connected to the joint, and a series of actual images (16) of the joint are obtained while the loads are applied. Then the at least one patient-specific geometrical model (1) is registered onto the actual images (16). Based thereon relative displacement and/or rotation of the at least one bone and/or at least one prosthesis is calculated as a function of the applied loads, and based thereon a measure of the laxity of the joint is determined. The invention further relates to a system for performing such a method and to a computer readable medium for performing such a method.
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
74.
JUNCTION TEMPERATURE MEASUREMENT IN A POWER SEMICONDUCTOR MODULE
A method for determining the temperature of a power semiconductor, where the power semiconductor includes an auxiliary emitter terminal and an emitter terminal, and a resistance component arranged between. The resistance component is thermally coupled and/or integrated into the semiconductor die. The resistance component is arranged between the auxiliary emitter terminal and the emitter terminal, and lies in the path of the control current. The resistance component has a temperature dependent resistance characteristic. A measurement circuit is used to inject a sufficient sensing current, or apply a suitable voltage, to the resistance component between the auxiliary emitter and emitter terminals, in order to generate an output signal that is dependent on the temperature dependent resistance of the resistance component. The output signal can be assessed with respect to a predefined temperature characteristic curve, obtained through a calibration procedure. Thus, the temperature of the semiconductor is measured.
REGION NORDJYLLAND, AALBORG UNIVERSITY HOSPITAL (Denmark)
AALBORG UNIVERSITET (Denmark)
Inventor
Thorlacius-Ussing, Ole
Ladefoged Rasmussen, Simon
Bygum Krarup, Henrik
Madsen, Poul Henning
Abstract
A method is provided for determining colorectal cancer, or the prognosis of a colorectal cancer in a subject, said method comprising in a sample from said subject determining the methylation status of a specific gene marker panel.
A method for analyzing a condition of a heart, comprises receiving a plurality of electrical signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
A61K 31/7115 - Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A neurofeedback system can be used by a person for training, so as to reduce musculoskeletal pain. The system comprises a non-invasive EEG sensor to sense EEG signal from the person. A processor system, e.g. a tablet or the like, receives data values from the EEG sensor and calculates a EEG power magnitude within the EEG alpha band accordingly. The processor system is programmed to determine a baseline value indicative of EEG alpha band power, and determine, in real-time, EEG alpha band power in response to data from the EEG sensor. On a display, the processor system displays a real-time visual indication of the EEG alpha band power values compared to said baseline value. At least one attribute, e.g. color, of the visual indication is determined in response to the real-time values being above or below a threshold which is determined in response to said baseline value. In preferred embodiments, a feedback device with a sensor for sensing a start of body movement of the person provides timing feedback to the processor system to allow calculation of EEG alpha power in the preparation phase before start of the movement, and to use this as the visual EEG feedback. Specific frequency-time signatures for a specific type of pain may be used for the baseline value used in the feedback to the person during training.
Adevice and method for human intention detection (HID). In preferred embodiments, it makes use of an array of force sensing resistors (FSRs) which are embedded inside a flexible band, which is capable of reading the muscle activity for different motion type and muscle forcein a human user. In one implementation of the invention two of such bands are attached to the forearm and the upper arm. From the readings of the sensors, the patterns for motion type and muscle forceare then distinguished autonomously by machine learning, a Support Vector Machine (SVM)algorithm, or a neural network. The method is advantageous e.g. the detection of dexterous motion of the arms, upon which assistive exoskeleton can be controlled for motion assistance. The invention can also be applicable to hand gestures recognition and bilateral rehabilitation, besides this the invention can be used to control lower body exoskeleton as well.
A method for assessing nerve fiber excitability is disclosed. The method comprises: arranging an electrode in contact with skin of a person; determining a first and a second threshold value based on a stimulation current pulse of a first and a second waveform, respectively; wherein said determining of the first threshold value and said determining of the second threshold value each comprises: repeatedly providing a stimulation current pulse of the first or second waveform, respectively, through the electrode, wherein a stimulation current strength is altered between repetitions; and receiving signals from an interaction element with which the person interacts, said signals from the interaction element providing an indication of the first threshold value or the second threshold value, respectively, corresponding to a stimulation current strength necessary to be perceived by the person; and determining at least one measure of psychophysical perception based on the determined first and second threshold values.
The present invention provides antisense oligonucleotides directed against immune checkpoints and methods and compositions of using such antisense oligonucleotides for the treatment of cancer.
Systems and methods for estimating cardiac strain and displacement using ultrasound are disclosed. According to an aspect, a method includes receiving frames of images acquired from a subject over a period of time. The method also includes determining, in the frames of images, speckles of features of the subject. Further, the method includes tracking bulk movement of the speckles in the frame of images. The method also includes determining displacement of at least a portion of the subject based on the tracked bulk movement.
A technology for quantifying, or determining an indication of, cardiorespiratory fitness is disclosed. A signal portion is obtained from a signal recorded with an accelerometer placed on the chest of a person. The accelerometer measures accelerations and vibrations of the chest wall of the person caused by myocardial movement. A maximum value is determined in the signal portion, and output information is provided indicating cardiorespiratory fitness based on the maximum value.
The present invention relates to a method and system for determining the aortic pulse wave velocity. The method comprises receiving an indication of a measurement of a length of a human aorta to provide an aortic length, arranging a first and second sound transducer outside the body of the patient, and identifying the opening of the aortic valve with measurement from the first sound transducer as a first time, and the pulse wave arrival time at the aortic bifurcation with measurements from the second sound transducer as a second time. The aortic transit time is determined based on the difference between the second time and the first time, and the aortic pulse wave velocity is calculated based on the aortic length and the aortic transit time.
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
The present invention relates to noncoding RNAs as novel disease targets, and methods of modulating the activity of such ncRNA targets in patients. In particular, the invention relates to modulation of long non-coding RNAs, such as circular RNAs (circRNAs) or large intergenic noncoding RNAs (lincRNAs) in cancer using antisense oligonucleotides.
The invention relates to a spherical joint mechanism comprising two revolute joints joined by a double parallelogram linkage. The double parallelogram linkage comprises a first linkage part hingedly connected to a first revolute joint at a distal end and a second linkage part hingedly connected to a second revolute joint at a distal end. The first linkage part comprises a first link arm and a second link arm, which first and second link arms are arranged to move parallel to each other. The second linkage part comprises a third link arm and a fourth link arm, which third and fourth link arms are arranged to move parallel to each other. A proximate end of the first linkage part and a proximate end of the second linkage part are mutually hingedly connected. The invention also relates to an exoskeleton with a shoulder joint or a hip joint comprising such a spherical joint mechanism.
Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides. As shown herein, the hetero chromatic HSATII satellite repeat is silenced in normal cells, but massively over expressed in epithelial cancers and in cancer cell lines when grown as xenografts or in 3D culture. Induction of HSATII RNA, either in xenografts or using in vitro reconstitution models, suggests the appearance of complementary DNA intermediates.
C12N 15/11 - DNA or RNA fragments; Modified forms thereof
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
89.
A CPN-BASED TOOL FOR THE STRATIFICATION OF ILLNESS SEVERITY IN PATIENTS SUSPECTED OF SEPSIS
There is presented a computer implemented method for calculating a probability of a clinical outcome for a patient, wherein the method comprises providing a maximum of 150 input parameters, such as a maximum of 20 input parameters, as input to a statistical model, and calculating the probability with the statistical model. The method in an embodiment further comprises performing with the statistical model an assessment of a severity of an illness of the patient, where said assessment is based partially or fully on the input parameters, and where said probability is based partially or fully on the severity of the patient's illness.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G06N 7/00 - Computing arrangements based on specific mathematical models
90.
A TRIPLE CO-CULTURE MODEL OF THE BLOOD-BRAIN BARRIER USING PRIMARY PORCINE BRAIN ENDOTHELIAL CELLS, PORCINE PERICYTES AND PORCINE ASTROCYTES
The present invention relates to an in vitro blood-brain-barrier (BBB) model comprising a porcine triple co-culture comprising porcine astrocytes, porcine primary brain endothelial cells (BEC's) and porcine pericytes. The invention also relates methods of producing such porcine triple co-cultures and uses thereof.
The present invention relates to an electrical machine stator comprising a plurality of stator segments (131,132,133), each segment comprises a first U-core and a second U-core wound with a winding, where the winding being arranged with at least one coil turn, each coil turn comprises a first axial coil segment and a second axial coil segment and one or more end segments, wherein the first and second axial coil segments are arranged in opposite directions to each other, and where the first U-core receives the first axial coil segment(s) and the second U-core receives the second axial coil segment(s), wherein the first U-core and the second U-core are located adjacent to each other, whereby the winding spans the first and second U-cores. The invention also relates to a SRM machine with a stator mentioned above and a rotor.
H02K 5/173 - Means for supporting bearings, e.g. insulating supports or means for fitting bearings in the bearing-shields using bearings with rolling contact, e.g. ball bearings
Described are network coding (NC) systems and techniques which utilize multiple composite extension finite fields to reduce complexity at various nodes in a network and also reduce overhead due to signal coding coefficients. A coding design uses a series of finite fields where increasingly larger fields are based on a previous smaller field. Techniques disclosed herein can be applied to existing systems using Random Linear Network Coding (RLNC) or Fulcrum codes.
The present invention describes an inflatable cuff 1 for inducing at least compressional or shear force on a subject and evaluating pain thresholds and/or sensitivity, pain modulation, spatial and/or temporal summation of pain, or descending inhibition of pain in the subject, said cuff comprising at least two separate chambers 2, 3 of which at least one is an inflation chamber 3 and at least one is a non-inflation chamber 2, wherein the inflation chamber 3 has a coupling 4for connection to a compressor or other activator device.
The present invention relates to a set of biomarkers, which can be used to determinethe risk of developing hypoxemia for subjects undergoingopen heart surgery with the use of cardiopulmonary bypass (CPB).
An apparatus for controlling force of a magnetic lead screw actuator includes a magnetic lead screw actuator, an external control module and at least one sensor device integrated within the magnetic lead screw actuator. The magnetic lead screw actuator includes an electric machine, a rotor, and a translator. The rotor includes a rotor magnet assembly forming first helical magnetic threads along the rotor and the translator includes a translator magnet assembly forming second helical magnetic threads along the translator. Rotation of the rotor by the electric machine effects linear translation of the translator by interaction of the first and second helical magnetic threads. The external control module is electrically operatively coupled to an electric machine controller of the magnetic lead screw actuator. The at least one sensor device integrated within the magnetic lead screw actuator is configured to measure a parameter indicative of a relative displacement between the rotor and the translator and this parameter is provided as feedback to the electric machine controller.
H02K 41/00 - Propulsion systems in which a rigid body is moved along a path due to dynamo-electric interaction between the body and a magnetic field travelling along the path
H02P 1/00 - Arrangements for starting electric motors or dynamo-electric converters
H02P 3/00 - Arrangements for stopping or slowing electric motors, generators, or dynamo-electric converters
H02P 5/00 - Arrangements specially adapted for regulating or controlling the speed or torque of two or more electric motors
H02P 6/00 - Arrangements for controlling synchronous motors or other dynamo-electric motors using electronic commutation dependent on the rotor position; Electronic commutators therefor
A method for assessing nerve fiber excitability is disclosed. The method comprises: arranging an electrode in contact with skin of a person; determining a first and a second threshold value based on a stimulation current pulse of a first and a second waveform, respectively; wherein said determining of the first threshold value and said determining of the second threshold value each comprises: repeatedly providing a stimulation current pulse of the first or second waveform, respectively, through the electrode, wherein a stimulation current strength is altered between repetitions; and receiving signals from an interaction element with which the person interacts, said signals from the interaction element providing an indication of the first threshold value or the second threshold value, respectively, corresponding to a stimulation current strength necessary to be perceived by the person; and determining at least one measure of psychophysical perception based on the determined first and second threshold values.
The present invention relates to an actuator system with a magnetic lead screw, comprises a magnetic rotor and a translator cylinder, the translator cylinder comprises a magnetic stator, the translator cylinder has a closed first end and a second end confined by a lid, the lid having a shaft opening for a shaft coupled to the magnetic rotor, wherein the magnetic rotor, when inserted in the translator cylinder, is arranged to translate a linear movement of the translator cylinder into a rotational movement of the magnetic rotor by using magnetic flux interacting between the magnetic stator and the magnetic rotor, said rotational movements is being transferred through a shaft, the lid with a shaft opening arranged for receiving the shaft, wherein the shaft is arranged to make both the linear and the rotational movement in the shaft opening, the lid being arranged for confining the second end of the translator cylinder, the translator cylinder confined by the lid forms, when divided by the magnetic rotor, a first chamber with a first volume and a second chamber with a second volume, wherein the first volume and the second volume changes as a function of the linear movement. The invention also relates to a method of operating an actuator system with a magnetic lead screw.
F16F 13/00 - Units comprising springs of the non-fluid type as well as vibration-dampers, shock-absorbers, or fluid springs
F04B 17/04 - Pumps characterised by combination with, or adaptation to, specific driving engines or motors driven by electric motors using solenoids
F04B 19/02 - Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups having movable cylinders
H02K 49/10 - Dynamo-electric clutches; Dynamo-electric brakes of the permanent-magnet type
B60G 15/04 - Resilient suspensions characterised by arrangement, location, or type of combined spring and vibration- damper, e.g. telescopic type having mechanical spring and mechanical damper
B60G 17/015 - Resilient suspensions having means for adjusting the spring or vibration-damper characteristics, for regulating the distance between a supporting surface and a sprung part of vehicle or for locking suspension during use to meet varying vehicular or s the regulating means comprising electric or electronic elements
F16H 25/24 - Elements essential to such mechanisms, e.g. screws, nuts
98.
A METHOD OF DIRECTLY DETERMINING THE WATER BALANCE IN FUEL CELLS
The present invention relates to a method of determining the water balance of a proton exchange membrane fuel cell, characterized by the net water drag coefficient (rd),by employing constant temperature anemometry (CTA). rd can be directly determined by collecting and processing a working voltage signal across a heated wire of a constant temperature anemometer located at the outlet of the anode of a fuel cell.
H01M 8/04119 - Arrangements for control of reactant parameters, e.g. pressure or concentration of gaseous reactants with simultaneous supply or evacuation of electrolyte; Humidifying or dehumidifying
99.
Method for functionalizing a solid material surface with self assembling or self aggregating cyclodextrins and products thereof
The present invention relates to a method for functionalizing a solid material surface with self assembling or self aggregating cyclodextrins, said method comprising the steps of: providing an adsorption solution comprising at least one modified cyclodextrin and at least one solvent; and contacting a solid material surface with the adsorption solution.
B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
A61F 13/15 - Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
100.
Method for file updating and version control for linear erasure coded and network coded storage
A method for use in a distributed storage system having a plurality of nodes, the method including receiving, at a source node, original data, encoding the original data into plurality of coded fragments using a linear code, transmitting at least a first one of the coded fragments from the source node to a first sink node. The method further includes receiving, at the source node, modified data, calculating, at the source node, a coded difference between the original data and the modified data, transmitting the coded difference from the source node to the first sink node; and recovering, at the first sink node, at least a first portion of the modified data using the coded difference and the at least a first one of the coded fragments.
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correction; Coding theory basic assumptions; Coding bounds; Error probability evaluation methods; Channel models; Simulation or testing of codes
H03M 13/15 - Cyclic codes, i.e. cyclic shifts of codewords produce other codewords, e.g. codes defined by a generator polynomial, Bose-Chaudhuri-Hocquenghem [BCH] codes
G06F 3/06 - Digital input from, or digital output to, record carriers
G06F 11/10 - Adding special bits or symbols to the coded information, e.g. parity check, casting out nines or elevens
H04L 29/08 - Transmission control procedure, e.g. data link level control procedure
G06F 11/14 - Error detection or correction of the data by redundancy in operation, e.g. by using different operation sequences leading to the same result