The present invention provides an electric power device comprising a plurality of power modules (PM1, PM2, PM3) each comprising at least one controllable wide bandgap semiconductor switch (SW1, SW2), wherein the plurality of power modules (PM1, PM2, PM3) are connected in parallel to an external power terminal (P_O). A gate driver system (GDS) serves to generate gate drive signals (GS) to the plurality of power modules (PM1, PM2, PM3). The gate driver system (GDS) comprises a master unit (M) and a plurality of connected slave driver units. The master unit (M) is configured to generate an electric power output (PWO, V+, V-, GND) and a gate control output (GCO). Each of the slave driver units (S1, S2, S3) are configured for connection to the electric power output (PWO) and the gate control output (GCO) of the master unit (M), and they each comprises a gate output (G_O) configured to output a gate control signal (GS) to a gate input (G) of one of the plurality of power modules (PM1, PM2, PM3) in response to the gate control output (GCO) of the master unit (M). A source output (S_O) is configured for connection to a source input (S) of the one of the plurality of power modules (PM1, PM2, PM3). To avoid high frequency gate voltage oscillations, a damping circuit (R, C) with at least a resistor (R) is connected between the gate output (G_O) and the source output (S_O). Further, decoupling inductors (I1, I2, I3) are connected to respective terminals configured for connection to the electric power output (PWO) of the master unit (M). This allows a low cost way of parallel connecting power module without instability problem due to gate oscillations, which can cause failure or permanent damage.
H03K 17/12 - Modifications pour augmenter le courant commuté maximal admissible
H03K 17/16 - Modifications pour éliminer les tensions ou courants parasites
H03K 17/785 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs opto-électroniques, c.-à-d. des dispositifs émetteurs de lumière et des dispositifs photo-électriques couplés électriquement ou optiquement commandant des commutateurs à transistors à effet de champ
2.
A PLANAR WINDING ASSEMBLY FOR POWER APPLICATIONS AND A METHOD OF MANUFACTURING SUCH ASSEMBLY
The present invention concerns a planar winding assembly for power applications, said assembly comprising a frame accommodating a stack of a plurality of printed circuit boards (PCBs), each comprising at least one conductive winding on the PCB, wherein the stack comprises an uppermost first PCB comprising an electrically insulating layer having a top surface and a bottom surface, where the bottom surface is provided with a conductive winding having a first winding pattern; at least one second PCB comprising an electrically insulating layer having a top surface and a bottom surface with conductive windings thereon, where the top surface is provided with the first winding pattern and the bottom surface is provided with a second winding pattern corresponding to the first winding pattern; a lowermost first PCB, which is similar to the uppermost first PCB but positioned with the winding facing upwards; means for holding the plurality of PCBs tightly against each other in the stacked configuration, and the frame encompasses the stack of PCBs. The invention further concerns a method of manufacturing a planar winding assembly for high-power applications.
H01F 27/32 - Isolation des bobines, des enroulements, ou de leurs éléments
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
3.
Inhibitory Nucleic Acids and Methods of Use Thereof
The present disclosure provides inhibitory nucleic acids, compositions comprising the inhibitory nucleic acids, and methods of using the inhibitory nucleic acids to treat various disorders.
A61K 31/7115 - Acides nucléiques ou oligonucléotides ayant des bases modifiées, c.-à-d. autres que l'adénine, la guanine, la cytosine, l'uracile ou la thymine
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c.-à-d. autres que des liaisons 3'-5' phosphodiester
The present invention provides an electric power module with at least two semiconductor switches, e.g. SiC or GaN semiconductor switches, connected in parallel between external terminals. At least one stabilizer circuit with a resistor connected between the first and second terminals is connected to: drain connections of the both of the semiconductor switches, and/or both of the source connections of the semiconductor switches. The stabilizer circuit component(s) can be connected to internal or external terminals of the power module. The stabilizer circuit is configured to damp an electric high frequency oscillation in the power module, such as an oscillation within 1-1000 MHz. For example, the stabilizer circuit may be a resistor of 1-100 Ω which has been found to damp high frequency oscillations in power modules caused by parasitics. The stabilizer circuit has been found to provide a high frequency oscillation damping effect to ensure a stable function of the power module. Since the stabilizer circuit is connected to connecting points with zero DC voltage difference, the power loss is minimal, and further the stabilizer circuit does not influence switching characteristics of the semiconductor switches. For high safety, the power module can be arranged inside a presspack casing.
H02M 7/48 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande
H02M 7/00 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continuTransformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif
H02M 3/00 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu
H02M 1/44 - Circuits ou dispositions pour corriger les interférences électromagnétiques dans les convertisseurs ou les onduleurs
H02M 1/088 - Circuits spécialement adaptés à la production d'une tension de commande pour les dispositifs à semi-conducteurs incorporés dans des convertisseurs statiques pour la commande simultanée de dispositifs à semi-conducteurs connectés en série ou en parallèle
H03K 17/16 - Modifications pour éliminer les tensions ou courants parasites
H05K 7/14 - Montage de la structure de support dans l'enveloppe, sur cadre ou sur bâti
H05K 7/10 - Montage de composants à contact par fiches
5.
A METHOD FOR COMPENSATING THE EFFECTS OF TIME DELAY FROM SAMPLING TO MEASUREMENT IN A BLOOD SAMPLE
The invention relates to a method for compensating the effects of time delay (TD) between sampling and actual measurement of acid-base, oxygenation and/or electrolyte status in a blood sample from a subject, such as a human patient. A mathematical model is simulating time development in the blood sample, the mathematical model having 1) a first sub-model describing red blood cell metabolism, and 2) a second sub-model describing the effect of the red blood cell metabolism on the whole blood acid-base chemistry. The mathematical model calculates from a time of measurement (Tm) to the time of sampling (Ts) a modified set of blood variables to compensate for a time delay (TD), e.g. by calculating backwards in time 0.5-3 hours. The invention can simulate the biochemical processes occurring in blood, and demonstrates the ability to simulate changes in measured blood variables over time. This may simplify transport and/or storage constraints of blood samples, and improve quality and accuracy of blood gas measurements.
G16C 60/00 - Science informatique des matériaux, c.-à-d. TIC spécialement adaptées à la recherche des propriétés physiques ou chimiques de matériaux ou de phénomènes associés à leur conception, synthèse, traitement, caractérisation ou utilisation
gg) together with the blood. The method has a mathematical model with physiological sub-models simulating development in blood together with this residual gas, including sub-models describing: 1) the diffusion of gasses between the residual gas and the blood sample, 2) the effects of the diffusing gas in the blood in the vacuum tube, and 3) the effects of the diffusing gas in the residual gas in the vacuum tube. The mathematical model then calculates a modified set of blood variables (BV) to compensate for the physical and/or chemical interactions between the residual gasses and the blood sample in the time following sampling and before blood gas measurement. By accounting for this contamination of the blood sample, calculation of the actual values of blood variables seen in the patient is possible.
G16C 60/00 - Science informatique des matériaux, c.-à-d. TIC spécialement adaptées à la recherche des propriétés physiques ou chimiques de matériaux ou de phénomènes associés à leur conception, synthèse, traitement, caractérisation ou utilisation
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
The present invention relates to a method for producing a membrane, wherein the method is a simple and cost-effective membrane production method. The method comprises the steps of mixing at least one monomer and/or oligomer with a pore- forming agent, adding an initiator and a substrate, and activating the initiator. The invention further relates to a membrane comprising a substrate coated with a cross-linked monomers and/or cross-linked oligomers having radical polymerizable functional groups and use thereof.
INESC TEC - INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES, TECNOLOGIA E CIÊNCIA (Portugal)
UNIVERSIDADE DO PORTO (Portugal)
AALBORG UNIVERSITET (Danemark)
Inventeur(s)
Gaudio, Alex
Renna, Francesco
Schmidt, Samuel
Tavares Coimbra, Miguel
Abrégé
Disclosed is a computer-implemented method for non-invasive estimation of Pulmonary Hypertension, PH, from heart sound signals. Consistent with the disclosure, the method includes the steps of: receiving a sound signal acquired from a beating heart of a subject over a predetermined time period; generating one or more 2D feature maps comprising a 2D feature map with the received sound signal where a first axis of the map is arranged over time and a second axis of the map is arranged over individual heartbeats; applying a pre-trained neural network to relate the generated one or more 2D feature maps with a training dataset of previously acquired and generated training 2D feature maps of a PH subject group and a non-PH subject group, thus to obtain an indicator of the presence of Pulmonary Hypertension. Also disclosed is a training method of said neural network and a system.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
9.
DC-AC POWER CONVERTER WITH SERIES CONNECTED POWER MODULES
The present invention provides an electric DC-AC power converter based on a plurality of DC-AC power modules connected with their AC output terminals connected in series. Each DC-AC power module: a circuit board (PCB or DBC) having a top side and a bottom side, a resonant DC-AC circuit comprising at least one semiconductor switch arranged for operation at a switching frequency of more than 1 MHz, and at least one capacitor connected to the semiconductor switch via conductive parts of the circuit board. At least one damping circuit with a resistor component, preferably with a resistor and capacitor in parallel, is connected in parallel with the conductive parts of the circuit board connecting the capacitor and the semiconductor switch. The damping circuit is tuned to dampen a resonance caused by parasitic behaviour of the circuit board, wherein said resonance has a frequency higher than the swithing frequency. In this way, the high frequency resonance caused by said parasitic behaviour of the circuit board can be eliminated. This high frequency resonance in each power module has been found to be critical for stability of a power converter based on series connected power modules. With the simple damping circuit, high power DC-AC conversion is possible using GaN or SiC semiconductor technology.
H02M 7/48 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande
H02M 7/5383 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur dans une configuration auto-oscillante
The invention discloses a method for removing methane (CH4) content in a fluid with a photoreactor system. The invention enables unprecedented high efficiency and fast removal by non-catalytic photochemical oxidation of methane by conveying a flow of a methane containing fluid through a mixing zone with water, which results in a mixed fluid, and illuminating the mixed fluid with UV radiation to generate photochemical oxidation of methane. The conveying and UV illuminating is performed so that the photochemical oxidation has reaction kinetics with a half-life (T50) of 60 minutes or less. This has been successfully demonstrated across a broad range of methane concentrations and operation conditions, and the invention may therefore provide a significant technological step forward for UV mediated photooxidation of the otherwise stable CH4 molecule to products with less radiative forcing potential and thereby reduce climate changes from methane.
B01D 53/00 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols
11.
A METHOD AND A SYSTEM FOR MANUFACTURING A PLANAR WINDING ASSEMBLY FOR POWER APPLICATIONS
The present invention concerns a method of manufacturing a modular planar winding assembly for power applications comprising a stack of planar members having electrically conductive windings on their sides for forming at least one coil, said method comprising the steps of providing a stack of planar members with electrically conductive bonding material on at least a portion of the windings and having a first and second terminal between the coil formed by the windings on the planar members; applying pressure to said stack of planar members for pressing the planar members together in the stack; providing an electric current between the first and second terminals for a period of time; and bonding the planar members in the stack together. The invention further concerns an arrangement for such manufacture and a planar member suitable for building such a stack.
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateursAppareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
12.
METHOD OF MANUFACTURING A VESSEL FOR STORAGE OF PRESSURIZED FLUID
The invention relates to a method of manufacturing a vessel (21) suitable for storage of pressurized fluid. The method comprises providing a body (22) forming an inner vessel cavity, the body having an inlet (25) providing an opening into the inner vessel cavity, providing at least one reinforcing element (1) and arranging it aligned with the inlet, winding continuous fibre reinforcement (24) around the body to form the vessel, and solidifying the matrix material impregnating the fibres. The at least one reinforcing element comprises a circumferential member (2) with a through-going hole (9), and a plurality of element fibres (3) extending away from the circumferential member while being in engagement with the circumferential member. During the winding, it is ensured that the element fibres are arranged in an overlapping and/or sandwiching engagement with the continuous fibre reinforcement over a region around the inlet.
The present invention relates to a cyclodextrin derivative of formula (I), wherein the cyclodextrin derivative has an average percentage of primary substitution (Rp) to total substitution with the substituted alkyl in the range of 15-99 %. The invention also relates to a composition comprising said cyclodextrin derivatives, a drug-cyclodextrin complex, use of a cyclodextrin derivative and a manufacturing method thereof.
The present invention concerns a planar winding assembly for power applications, said assembly comprising a frame accommodating a stack of a plurality of printed circuit board (PCB) modules, each comprising a plurality of conductive windings on the PCB module, wherein the stack comprises an uppermost first PCB module comprising an electrically insulating layer having a first surface and a second surface, where the second surface is provided with at least two conductive winding sections having a first winding pattern and where said second surface is facing downwards; at least one second PCB module comprising an electrically insulating layer having a top surface and a bottom surface, where both surfaces are provided with a second winding pattern corresponding to the first winding pattern; a lowermost first PCB module, which is positioned with said first winding pattern on the second surface facing upwards; means for holding the plurality of PCB modules tightly against each other in the stacked configuration, said holding means comprising a frame encompasses the stack of PCB modules.
H01F 27/30 - Fixation ou serrage de bobines, d'enroulements ou de parties de ceux-ci entre euxFixation ou montage des bobines ou enroulements sur le noyau, dans l'enveloppe ou sur un autre support
H05K 1/14 - Association structurale de plusieurs circuits imprimés
15.
A DEVICE AND A METHOD FOR SENSING VIBRATIONS IN A HUMAN'S SKIN EMANATING FROM BLOOD FLOW BELOW THE SKIN
The present invention relates to a device (1) and a method for sensing vibrations in a human's skin (2) emanating from blood flowing in a natural or artificial blood vessel or an arteriovenous fistula (AVF) (3) located below the skin. The device comprises a sensor (4), a controller (5), a transmitter (6), and an electrical power source (7). In particular, the invention relates to such a device that is configured to be fastened to the human and carried around by the human during use of the device. The measured signals are analysed, and if the blood flow is below a pre-selected blood flow threshold, an alarm signal is issued to warn e.g. a responsible medical doctor that there is a need for further assessment.
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/0295 - Mesure du débit sanguin utilisant la pléthysmographie, c.-à-d. par mesure des variations du volume d'une partie du corps induites par la circulation du sang qui traverse cette partie, p. ex. pléthysmographie par impédance
An air flow measurement system for determining an air flow value indicative of air flow in an associated air duct system with an air duct and a controllable damper to control air flow in the air duct by means of a damper blade which has a controllable position, such as around an axis of rotation. An air flow sensor, preferably an EFV based sensor, is arranged for being positioned inside the associated air duct at or near a wall of the air duct and downstream of the controllable damper in proximity to the controllable damper. The air flow sensor is connected to a flow measurement system, and a processor processes an output from the flow measurement circuit to determine a measured air speed accordingly. The processor can then calculate the air flow value based on the measured air speed, preferably further based on a damper blade position, and a correction value. The measurement system can measure very low air speeds e.g. in a ventilation duct with high accuracy, such as down to 0.2 m/s. To protect the air flow sensor from dirt particles, an obstacle element can be placed upstream of the sensor, i.e. in the form of a pin or rod.
G01F 1/20 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets mécaniques par détection des effets dynamiques de l’écoulement
G01F 1/26 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets mécaniques par détection des effets dynamiques de l’écoulement par débitmètres à section variable du type à clapet
G01F 15/00 - Détails des appareils des groupes ou accessoires pour ces derniers, dans la mesure où de tels accessoires ou détails ne sont pas adaptés à ces types particuliers d'appareils, p. ex. pour l'indication à distance
G01F 1/36 - Mesure du débit volumétrique ou du débit massique d'un fluide ou d'un matériau solide fluent, dans laquelle le fluide passe à travers un compteur par un écoulement continu en utilisant des effets mécaniques en mesurant la pression ou la différence de pression la pression ou la différence de pression étant produite par une contraction de la veine fluide
The present invention relates to multi-step or cascade extraction process for extracting bio-active compounds from non-food fractions of saline, fresh green or lignified biomasses such as halophytes and seaweed. The extraction processes can also be used for treating circular feedstocks, such as polyphenolic rich circular feedstocks.
PROFESSIONSHØJSKOLEN VIA UNIVERSITY COLLEGE (Danemark)
Inventeur(s)
Thomsen, Mette Hedegaard
Stein, Jakob Lykke
Chaturvedi, Tanmay
Skovhus, Torben Lund
Abrégé
The present invention relates to methods of producing halophyte extract. In particular the present invention relates to the use of halophyte extract for reducing MIC-bacteria, especially sulphate-reducing bacteria and/or biofilm.
A01N 65/12 - Asteraceae ou Compositae [famille de l'aster ou du tournesol], p. ex. marguerite, pyrèthre, artichaut, laitue, tournesol, armoise ou estragon
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
19.
METHOD FOR PRODUCING A FOOD GRADE PROTEIN PRODUCT AND/OR A FEED PROTEIN PRODUCT FROM PLANT MATERIAL
A method for producing plant derived protein products is provided. The method includes extraction and purification of plant protein fractions, which may be used for food consumption and/or feed for animals. A plant protein juice is extracted from a green plant material, and used for production of a purified functional 'white' food protein product and/or a 'green' feed protein product.
A23J 1/00 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
A23K 20/147 - Dérivés polymériques, p. ex. peptides ou protéines
A method for producing plant derived protein products is provided. The method includes extraction and purification of plant protein fractions, which may be used for food consumption and/or feed for animals. A plant protein juice is extracted from a green plant material, and used for production of a purified functional 'white' food protein product and/or a 'green' feed protein product.
A23J 1/00 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
A23K 20/147 - Dérivés polymériques, p. ex. peptides ou protéines
Disclosed is an energy harvester for generating electric energy from an external vibratory force, such as a vibratory force caused by movement of a part of a living human or animal. The energy harvester has a compartment (CMP1, CMP2) with wall element(s) forming a cavity inside. At least one wall element of the compartment has a piezoelectric element connected to an electric output terminal. An impact object (BL) is positioned inside the cavity of the compartment. The impact object is configured to move inside the cavity and to generate an impact on a surface of the wall element(s), so as to cause the piezo-electric element to generate an electric output on the electric output terminal. The compartment may have a cubic shape, e.g. made of a single piezoelectric element folded into shape, e.g. a two-layer piezoelectric element. The impact object may be a metal or ceramics object with a spherical shape. Especially, the energy harvester may be used to power an implantable medical device, e.g. an intra-cardiac pacemaker. An energy harvester housing within an intra-cardiac pacemaker has been tested to be sufficient for powering the pacemaker stimulation circuit by the vibratory force caused by heartbeats.
H02N 2/18 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction fournissant une sortie électrique à partir d'une entrée mécanique, p. ex. générateurs
A61N 1/375 - Aménagements structurels, p. ex. boîtiers
The present invention relates inter alia to a hydraulic device which may be used as a hydraulic transformer. The hydraulic device comprising a housing, a first tubular cavity and a second tubular cavity both being provided within the housing. A piston structure is reciprocatable arranged within the housing and comprises a first piston and a second piston; wherein the first piston divides the first cavity into two chambers, and the second piston divides the second cavity into two chambers. Fluid passages for individually exchanging fluid between the chambers and the exterior of the housing are provided and each fluid passage comprising a controllable shut-off valve so as to provide the reciprocating movement of the piston structure by exchanging fluid between exterior and the two chambers of the first cavity, and said hydraulic transformed being configured to control the shut-off valves to selectively be in a closed state or in an open state.
F15B 11/02 - Systèmes comportant essentiellement des moyens particuliers pour commander la vitesse ou la puissance d'un organe de sortie
F15B 11/028 - Systèmes comportant essentiellement des moyens particuliers pour commander la vitesse ou la puissance d'un organe de sortie pour régler la puissance
23.
POWER MODULE WITH REDUCED TRIPLE POINT MAXIMUM ELECTRIC FIELD
The present invention provides a power module, especially configured for Medium Voltage (MV) applications. The power module comprises an electrically non- conductive substrate with first and second electrically conductive pads connected to respective external terminals. The first conductive pad is configured for connection to an electric high voltage (HV) potential, such as in the MV range, e.g. 15 kV, and the second conductive pad is configured for connection to electric ground. A semiconductor chip, such as a Silicon Carbide based chip, is directly secured to the first or the second conductive pad. At least a first electrically conductive guard structure is arranged on the upper surface of the non-conductive substrate so as to form a closed ring around the first conductive pad. This first guard structure is configured for electric connection to an electrical potential between electric ground and the HV potential, such as an electric potential of at least 0.5 times the HV potential, such as 0.7-0.9 times the HV potential. Preferred embodiments illustrate how a voltage divider structure can be integrated into the power module to provide the optimal electric potential for the guard structure to give optimal reduction of maximum electric field in the trench.
H01L 23/24 - Matériaux de remplissage caractérisés par le matériau ou par ses propriétes physiques ou chimiques, ou par sa disposition à l'intérieur du dispositif complet solide ou à l'état de gel, à la température normale de fonctionnement du dispositif
H01L 23/373 - Refroidissement facilité par l'emploi de matériaux particuliers pour le dispositif
H01L 23/62 - Protection contre l'excès de courant ou la surcharge, p. ex. fusibles, shunts
H01L 25/07 - Ensembles consistant en une pluralité de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide les dispositifs étant tous d'un type prévu dans une seule des sous-classes , , , , ou , p. ex. ensembles de diodes redresseuses les dispositifs n'ayant pas de conteneurs séparés les dispositifs étant d'un type prévu dans la sous-classe
The present invention relates to compounds of Non-Ribosomal Peptide Synthetase and methods of analysing them. In particular the present invention relates to the use of these compounds in vaccines and antigen-binding molecules targeting these compounds.
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
C07K 14/37 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de champignons
C12N 15/80 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons
25.
A PLANAR WINDING ASSEMBLY FOR POWER APPLICATIONS AND A METHOD OF MANUFACTURING SUCH ASSEMBLY
The present invention concerns a planar winding assembly for power applications, said assembly comprising a frame accommodating a stack of a plurality of printed circuit boards (PCBs), each comprising at least one conductive winding on the PCB, wherein the stack comprises an uppermost first PCB comprising an electrically insulating layer having a top surface and a bottom surface, where the bottom surface is provided with a conductive winding having a first winding pattern; at least one second PCB comprising an electrically insulating layer having a top surface and a bottom surface with conductive windings thereon, where the top surface is provided with the first winding pattern and the bottom surface is provided with a second winding pattern corresponding to the first winding pattern; a lowermost first PCB, which is similar to the uppermost first PCB but positioned with the winding facing upwards; means for holding the plurality of PCBs tightly against each other in the stacked configuration, and the frame encompasses the stack of PCBs. The invention further concerns a method of manufacturing a planar winding assembly for high-power applications.
H01F 27/30 - Fixation ou serrage de bobines, d'enroulements ou de parties de ceux-ci entre euxFixation ou montage des bobines ou enroulements sur le noyau, dans l'enveloppe ou sur un autre support
26.
INHIBITORY NUCLEIC ACIDS AND METHODS OF USE THEREOF
A61K 31/712 - Acides nucléiques ou oligonucléotides ayant des sucres modifiés, c.-à-d. autres que le ribose ou le 2'-désoxyribose
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c.-à-d. autres que des liaisons 3'-5' phosphodiester
A61K 47/14 - Esters d’acides carboxyliques, p. ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
A61P 3/08 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose
27.
INHIBITORY NUCLEIC ACIDS AND METHODS OF USE THEREOF
The present disclosure provides inhibitory nucleic acids, compositions comprising the inhibitory nucleic acids, and methods of using the inhibitory nucleic acids to treat various disorders.
A61K 31/712 - Acides nucléiques ou oligonucléotides ayant des sucres modifiés, c.-à-d. autres que le ribose ou le 2'-désoxyribose
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c.-à-d. autres que des liaisons 3'-5' phosphodiester
A61K 47/14 - Esters d’acides carboxyliques, p. ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
A61K 47/34 - Composés macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyesters, acides polyaminés, polysiloxanes, polyphosphazines, copolymères de polyalkylène glycol ou de poloxamères
A61P 3/08 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
28.
REDUCING PARASITIC CAPACITANCE IN MEDIUM-VOLTAGE INDUCTORS
The present invention relates to inter alia to a conductor having at least two windings where each of the two windings preferably has layered configuration of turns, where each layer of a winding preferably is serially connected. Further, layers are typically distanced from each other, preferably by use of layer spacers, which preferably provide a void, or a number of voids, in between each layers. Conductors according to the present invention have shown to lessen, such as reducing parasitic capacitance.
H01F 27/34 - Moyens particuliers pour éviter ou réduire les effets électriques ou magnétiques indésirables, p. ex. pertes à vide, courants réactifs, harmoniques, oscillations, champs de fuite
H01F 1/153 - Alliages métalliques amorphes, p. ex. métaux vitreux
A61B 8/02 - Mesure du pouls ou du rythme cardiaque
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
31.
EXPLAINABLE DEEP LEARNING METHOD FOR NON-INVASIVE DETECTION OF PULMONARY HYPERTENSION FROM HEART SOUNDS
INESC TEC - INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES, TECNOLOGIA E CIÊNCIA (Portugal)
UNIVERSIDADE DO PORTO (Portugal)
AALBORG UNIVERSITET (Danemark)
Inventeur(s)
Gaudio, Alex
Renna, Francesco
Schmidt, Samuel
Tavares Coimbra, Miguel
Abrégé
The present document discloses a computer-implemented method for non-invasive estimation of Pulmonary Hypertension, PH, from heart sound signals, comprising the steps: receiving a sound signal acquired from a beating heart of a subject over a predetermined time period; generating one or more 2D feature maps comprising a 2D feature map with the received sound signal where a first axis of the map is arranged over time and a second axis of the map is arranged over individual heartbeats; applying a pre-trained neural network to relate the generated one or more 2D feature maps with a training dataset of previously acquired and generated training 2D feature maps of a PH subject group and a non-PH subject group, thus to obtain an indicator of the presence of Pulmonary Hypertension. It further discloses a training method of said neural network and a system.
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 8/02 - Mesure du pouls ou du rythme cardiaque
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
32.
A PLANNING METHOD FOR PROCESSING AN ELEMENT INTO A FINAL ELEMENT
The present invention relates to a computer-implemented method for planning laser processing of one or more elements into one or more final elements, such as planning a process of creating a final element from a sheet metal by creating a 5 model of both the sheet metal to be processed and the final element and determining a plurality of processing steps to create said final element. The method is based on a plurality of rules for taking into account, how to process the element by a plurality of processing steps, said processing steps comprising laser process specifications and generating at least a first set of instructions for an 10 associated laser processing device.
G05B 19/4097 - Commande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique caractérisée par l'utilisation de données de conception pour commander des machines à commande numérique [CN], p. ex. conception et fabrication assistées par ordinateur CFAO
33.
A DEVICE AND A METHOD FOR SENSING VIBRATIONS IN A HUMAN'S SKIN EMANATING FROM BLOOD FLOW BELOW THE SKIN
The present invention relates to a device (1) and a method for sensing vibrations in a human's skin (2) emanating from blood flowing in a natural or artificial blood vessel or an arteriovenous fistula (AVF) (3) located below the skin. The device comprises a sensor (4), a controller (5), a transmitter (6), and an electrical power source (7). In particular, the invention relates to such a device that is configured to be fastened to the human and carried around by the human during use of the device. The measured signals are analysed, and if the blood flow is below a pre- selected blood flow threshold, an alarm signal is issued to warn e.g. a responsible medical doctor that there is a need for further assessment.
A61B 5/0295 - Mesure du débit sanguin utilisant la pléthysmographie, c.-à-d. par mesure des variations du volume d'une partie du corps induites par la circulation du sang qui traverse cette partie, p. ex. pléthysmographie par impédance
34.
METHOD OF MANUFACTURING A FIBRE REINFORCED COMPOSITE COMPONENT HAVING A REINFORCED HOLE
The invention relates to a method of manufacturing a composite component with continuous fibre reinforcement and having a reinforced hole. The hole is reinforced by incorporation of at least one reinforcing element (1) into a layered arrangement of continuous fibres. The reinforcing element comprises a circumferential member (2) with a through-going first hole (9) and a plurality of continuous element fibres (3). The at least one reinforcing element (1) is arranged in an overlapping and/or sandwiching engagement with the layered arrangement so that the first hole is arranged within and aligned with a second hole (8) to be reinforced. Hereby an externally force applied to the reinforced hole during use of the component is distributed over a larger region of the material around the hole. Thereby the component can be joined to another part e.g. by a bolted connection which allows for disassembly that would not have been possible if they were joined by adhesive joining.
B29C 70/68 - Façonnage de matières composites, c.-à-d. de matières plastiques comprenant des renforcements, des matières de remplissage ou des parties préformées, p. ex. des inserts en incorporant ou en surmoulant des parties préformées, p. ex. des inserts ou des couches
The invention relates to a screw pile (100) adapted for being installed in the ground for providing foundation for a construction (800) or a like, said screw pile comprising an elongated body (200), wherein at least one of the upper part (210), middle part (220) or lower part (230) of the elongated body comprises one or more threaded portions (300), and wherein at least a portion of the volume of the screw pile is concrete (400), said portion of concrete being 50% or more of the volume of the screw pile. In some embodiments, only the lower part of the screw pile has a threaded portion and is made of metal, while an elongated shaft is made of at least 70% concrete. Furthermore, the invention relates to a method of manufacturing a screw pile, said method comprising at least the steps of: providing a mold (600), providing a wet concrete mixture (700) in a liquid form, optionally, providing reinforcement (500), preferably being bars, wires or spirals, optionally, inserting the reinforcement into the concrete mixture, filling the mold with the concrete mixture.
The present invention relates to a method for installation and validation of a screw pile (100) being installed in the ground, said method comprising the steps of: placing at least one screw pile at a location, providing means for screwing (200) the at least one screw pile into the ground, starting screwing the at least one screw pile into the ground by the means for screwing, during the process of screwing measuring at least a set of installation parameters comprising: torsion and/or torque and penetration depth, generating an output indicative of said installation parameters, and providing an installation validation, e.g. an installation validation document or file, of the at least one screw pile. In some embodiments the method comprises to stop screwing the screw pile into the ground when predetermined thresholds of installation parameters are reached. In some embodiments the method comprises generating a data on how the screw pile was installed, e.g. screw direction and rotation versus penetration depth data, e.g. to be included as part of the installation validation. Furthermore, the present invention relates to an installation validation document for at least one screw pile installed in the ground, moreover the invention relates to a computer program.
The invention relates to a load-bearing test apparatus adapted to test the load-bearing capacity of an associated pile installed in the ground, preferably an associated screw pile, the load-bearing test apparatus comprising: a load carrier having at least one main protrusion and at least one receiving portion, a load being positioned on the load carrier or being an integrated part of the carrier, preferably being a plurality of load plates, a shaft adapted for allowing the load carrier to slide up and down in a vertical direction, at least one connecting piece for attachable connecting the load carrier to the associated pile, and a locking system. Furthermore, the invention relates to a method for testing the load-bearing capacity of a pile installed in the ground.
The present invention provides a power module arranged to receive a DC electric input signal at first and second connection terminals (A, B), and to output an AC electric output signal at third and fourth connection terminals (C, D). A set of capacitors (CAP1, CAP2) are connected between respective sets of connection terminals (A, B, C, D). Two inductors (L1, L2) are connected at least to respective connection terminals (C, D), such as the first inductor (L1) being connected between on set of connection terminals (A, C), and the second inductor (L2) being connected between another set of connection terminals (B, D). A switch network (SWN) with at least one electrically controllable bidirectional two-quadrant switch (s1), is connected between at least two of the four connection terminals (A, B, C, D). The at least one witch (s1) is arranged for being controlled according to a switching cycle, so as to provide an average voltage (V1) of zero across the first inductor (L1) over one switching period of the switching cycle, and to provide an average voltage (V2) of zero across the second inductor (L2) over one switching period. The power module is simple, and can be implemented with only one single switch per module. A DC to AC power converter can be build of a number of interconnected power modules, and such power converter can be designed to provide an AC output voltage in the kV range at a power in the kW range, at a frequency of up to such as 40 MHz.
H02M 1/00 - Détails d'appareils pour transformation
H02M 7/48 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande
H02M 7/49 - Combinaison des formes de tension de sortie d'une pluralité de convertisseurs
H02M 7/483 - Convertisseurs munis de sorties pouvant chacune avoir plus de deux niveaux de tension
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
39.
A METHOD FOR PROCESSING ELEMENTS INTO FINAL ELEMENTS
The present invention relates to method for cutting and shaping and/or bending a metal element into a final element using laser means, the method comprising providing data containing a final model of the final element and providing a set of instructions as to how to process the final element from the metal element, measure the processing and provide at least a second set of instructions based on feedback, such as geometrical measurements during said processing, so as to create a final element.
G05B 19/18 - Commande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique
40.
METHOD FOR CONTROLLING AN ORTHOPEDIC DEVICE AND ORTHOPEDIC DEVICE
The invention deals with a method for controlling an orthopedic device, the method comprising the following steps of: —Providing input signals, —Using said input signals as input variables of a musculoskeletal model, —Determining feedback signals using said musculoskeletal model, —Transmitting said feedback signals to said user of said orthopedic device.
A61F 2/72 - Commandes bioélectriques, p. ex. myoélectriques
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p. ex. stimulateurs cardiaques
41.
ENERGY HARVESTER BASED ON PIEZOELECTRIC IMPACT COMPARTMENT
Disclosed is an energy harvester for generating electric energy from an external vibratory force, such as a vibratory force caused by movement of a part of a living human or animal. The energy harvester has a compartment (CMP1, CMP2) with wall element(s) forming a cavity inside. At least one wall element of the compartment has a piezoelectric element connected to an electric output terminal. An impact object (BL) is positioned inside the cavity of the compartment. The impact object is configured to move inside the cavity and to generate an impact on a surface of the wall element(s), so as to cause the piezoelectric element to generate an electric output on the electric output terminal. The compartment may have a cubic shape, e.g. made of a single piezoelectric element folded into shape, e.g. a two-layer piezoelectric element. The impact object may be a metal or ceramics object with a spherical shape. Especially, the energy harvester may be used to power an implantable medical device, e.g. an intra-cardiac pacemaker. An energy harvester housing within an intra-cardiac pacemaker has been tested to be sufficient for powering the pacemaker stimulation circuit by the vibratory force caused by heartbeats.
H02N 2/18 - Machines électriques en général utilisant l'effet piézo-électrique, l'électrostriction ou la magnétostriction fournissant une sortie électrique à partir d'une entrée mécanique, p. ex. générateurs
The present invention relates to glass-based substrates and articles that can be hydrated under special circumstances to increase their crack resistance and induce self-healing, and to processes for their production.
C03C 3/083 - Compositions pour la fabrication du verre contenant de la silice avec 40 à 90% en poids de silice contenant de l'oxyde d'aluminium ou un composé du fer
C03C 3/085 - Compositions pour la fabrication du verre contenant de la silice avec 40 à 90% en poids de silice contenant de l'oxyde d'aluminium ou un composé du fer contenant un oxyde d'un métal divalent
C03C 3/091 - Compositions pour la fabrication du verre contenant de la silice avec 40 à 90% en poids de silice contenant du bore contenant de l'aluminium
C03C 23/00 - Autres traitements de surface du verre, autre que sous forme de fibres ou de filaments
C03C 21/00 - Traitement du verre, autre que sous forme de fibres ou de filaments, par diffusion d'ions ou de métaux en surface
C07H 21/02 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le ribosyle comme radical saccharide
A61K 31/712 - Acides nucléiques ou oligonucléotides ayant des sucres modifiés, c.-à-d. autres que le ribose ou le 2'-désoxyribose
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c.-à-d. autres que des liaisons 3'-5' phosphodiester
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
The present invention relates inter alia to a hydraulic device which may be used as a hydraulic transformer. The hydraulic device comprising a housing, a first tubular cavity and a second tubular cavity both being provided within the housing. A piston structure is reciprocatable arranged within the housing and comprises a first piston and a second piston; wherein the first piston divides the first cavity into two chambers, and the second piston divides the second cavity into two chambers. Fluid passages for individually exchanging fluid between the chambers and the exterior of the housing are provided and each fluid passage comprising a controllable shut-off valve so as to provide the reciprocating movement of the piston structure by exchanging fluid between exterior and the two chambers of the first cavity, and said hydraulic transformed being configured to control the shut-off valves to selectively be in a closed state or in an open state.
F15B 3/00 - Amplificateurs ou convertisseurs de pression de fluide, p. ex. échangeurs de pressionTransmission de la pression d'un système à fluide à un autre, sans contact entre les fluides
F15B 11/032 - Systèmes comportant essentiellement des moyens particuliers pour commander la vitesse ou la puissance d'un organe de sortie pour régler la puissance au moyen de convertisseurs de pression de fluide
F15B 11/036 - Systèmes comportant essentiellement des moyens particuliers pour commander la vitesse ou la puissance d'un organe de sortie pour régler la puissance au moyen de servomoteurs comportant plusieurs chambres de travail
45.
Non-invasive front-end for power electronic monitoring
A front-end device for monitoring operation of an associated electric power device with semiconductor power switches generating a power output, e.g. a three-phase power output. The front-end device has input terminals arranged for connection to the electric phase(s) of the power output of the associated electric power device, and an electric circuit connected to the input terminals and connected to at set of output terminals. The electric circuit has a passive interconnection comprising electric semiconductor switches and diodes. The electric circuit serves to electrically block any high voltage component from the input terminals from reaching the output terminals, while allowing an on-state voltage of at least one semiconductor power switch in the associated electric power device to pass to the at least two output terminals. The front-end allows low voltage equipment to be connected to its output terminals for determining an on-state voltage of switches of the electric power device. Especially, embodiments with self-powered reference voltage circuits provided by zener diodes allow compact low cost versions for use in e.g. portable test equipment or as part of permanently installed health condition monitoring of power devices. The front-end device can be used as a simple and low cost solution for non-invasive health condition monitoring of power devices, e.g. power converters in such as power electric generation system or electric vehicles. Such monitoring allows predictive maintenance to be performed to avoid any faults in the power device that may cause permanent damages.
The invention provides a non-invasive tongue based with a tongue sensor device arranged for position in the oral cavity of the user. A sensor panel to be placed on an upper part of the oral cavity of the user, and having a 2D array of activation zones and related electric coils. A guide structure, e.g. a metal or polymer frame, carries a ferrous or metallic activation unit movably in a plane upon manipulation by the user's tongue. This allows the user to position the activation unit in relation the activation zones. The guide structure allows the activation unit to move also perpendicular to the plane, to allow the user's tongue to manipulate the activation unit near one activation zone for activation of the activation zone. An electronic circuit inductively senses activation of any one or more of the plurality of activation zones and related electric coils and generates an output accordingly, e.g. a wireless RF output. E.g. a frame structure of metal wires or bars can be used to implement the guide structure, thus allowing the activation unit, e.g. a metal sphere or cylinder, to form an integrated part of the rather than being mounted in an invasive way on the user's tongue.
A61F 4/00 - Procédés ou dispositifs permettant à des patients ou à des personnes handicapées de commander un appareil ou un dispositif ne faisant pas partie du corps
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
47.
ANTISENSE OLIGONUCLEOTIDES (ASOs) DESIGNED TO INHIBIT IMMUNE CHECKPOINT PROTEINS
The present invention provides antisense oligonucleotides directed against immune checkpoints and methods and compositions of using such antisense oligonucleotides for the treatment of cancer.
The invention relates to a hand orthosis (1) for assisting the movements of a user's hand. The hand orthosis comprises a soft glove (2) adapted to receive at least a part of the user's hand with finger sections of the glove receiving each of the user's fingers. It further comprises at least one actuator box (3), and a power transmission (4) for transferring forces from the at least one actuator box to different parts of the glove via exo-tendons (5). The exo-tendons are arranged on a dorsal side, on a palmar side, or on both a dorsal side and a palmar side of the glove. The exo-tendons are arranged so that the glove can assist flexion, extension, or both extension and flexion of the fingers, respectively and so that the exo-tendons act on the fingers to produce motion that mimics the movement of a human hand. The hand orthosis provides different grasp types, self- adaptation of the fingers' motion to the shape of the object, and physiologically appropriate distribution of finger forces.
A61F 5/01 - Dispositifs orthopédiques, p. ex. dispositifs pour immobiliser ou pour exercer des pressions de façon durable pour le traitement des os fracturés ou déformés, tels que éclisses, plâtres orthopédiques ou attelles
49.
REDUCING PARASITIC CAPACITANCE IN MEDIUM-VOLTAGE INDUCTORS
The present invention relates to inter alia to a conductor having at least two windings where each of the two windings preferably has layered configuration of turns, where each layer of a winding preferably is serially connected. Further, layers are typically distanced from each other, preferably by use of layer spacers, which preferably provide a void, or a number of voids, in between each layers. Conductors according to the present invention have shown to lessen, such as reducing parasitic capacitance.
The proposed technology relates to the quantifying of cardiorespiratory fitness. It includes the obtaining (102) of a seismocardiogram (SCG) recorded with an accelerometer (14) configured to measure accelerations and vibrations of the chest wall of a person (18) caused by myocardial movement. Properties of a first signal feature (AC) in the seismocardiogram (SCG) are determined (104), wherein the first signal feature (AC) corresponds to the aortic valve closure (AC) of a heartbeat. A measure indicating cardiorespiratory fitness (VO2 max) is then determined (106) based on the properties of first signal feature (AC).
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p. ex. la physiothérapie, l’acupression ou les exercices
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
51.
BIOMARKERS FOR PULMONARY EMBOLISM IN EXHALED BREATH CONDENSATE
Region Nordjylland, Aalborg University Hospital (Danemark)
Aarhus Universitet (Danemark)
Aalborg Universitet (Danemark)
Inventeur(s)
Gade, Inger Lise
Honoré, Bent
Kristensen, Søren Risom
Abrégé
A method is provided for determining pulmonary embolism and/or increased risk thereof in a human being, comprising collecting a sample of exhalation air from said human being and determining the presence or absence in said exhaled air of one or more biomarkers associated with pulmonary embolism. Additionally, a kit that comprises the means for detecting at least one biomarker associated with pulmonary embolism or risk thereof is provided.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
52.
Therapeutic Targeting of a microRNA to Treat Duchenne Muscular Dystrophy
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61K 31/7115 - Acides nucléiques ou oligonucléotides ayant des bases modifiées, c.-à-d. autres que l'adénine, la guanine, la cytosine, l'uracile ou la thymine
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
A61K 31/711 - Acides désoxyribonucléiques naturels, c.-à-d. contenant uniquement des 2'-désoxyriboses liés à l'adénine, la guanine, la cytosine ou la thymine et ayant des liaisons 3'-5' phosphodiester
53.
Spherical mechanism constructed with scissors linkages with control means
rhombi or parallelograms. Each of the linkage elements is rotationally connected to one of the other linkage elements via a revolute joint (5) at or near the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at or near the second end. The linkage elements are shaped, dimensioned and arranged so that the axes of all the revolute joints coincide at one common remote centre of motion (RCM). Furthermore, the mechanism is grounded or connected or connectable to a first external member (7) at a proximal end and is rotationally connected or connectable to a second external member (9) at an opposite distal end. Hereby a spherical linkage mechanism with three DOFs is obtained. The spherical scissors linkage mechanism may further comprise a motion controlling mechanism at the proximal and/or at the distal end. It further comprises actuator means as control means.
The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
55.
METHOD OF MANUFACTURING A FIBRE REINFORCED COMPOSITE COMPONENT HAVING A REINFORCED HOLE
The invention relates to a method of manufacturing a composite component with continuous fibre reinforcement and having a reinforced hole. The hole is reinforced by incorporation of at least one reinforcing element (1) into a layered arrangement of continuous fibres. The reinforcing element comprises a circumferential member (2) with a through-going first hole (9) and a plurality of continuous element fibres (3). The at least one reinforcing element (1) is arranged in an overlapping and/or sandwiching engagement with the layered arrangement so that the first hole is arranged within and aligned with a second hole (8) to be reinforced. Hereby an externally force applied to the reinforced hole during use of the component is distributed over a larger region of the material around the hole. Thereby the component can be joined to another part e.g. by a bolted connection which allows for disassembly that would not have been possible if they were joined by adhesive joining.
B29C 70/20 - Façonnage de matières composites, c.-à-d. de matières plastiques comprenant des renforcements, des matières de remplissage ou des parties préformées, p. ex. des inserts comprenant uniquement des renforcements, p. ex. matières plastiques auto-renforçantes des renforcements fibreux uniquement caractérisées par la structure des renforcements fibreux utilisant des fibres de grande longueur, ou des fibres continues orientées dans une seule direction, p. ex. mèches ou autres fibres parallèles
B29C 70/30 - Façonnage par empilage, c.-à-d. application de fibres, de bandes ou de feuilles larges sur un moule, un gabarit ou un noyauFaçonnage par pistolage, c.-à-d. pulvérisation de fibres sur un moule, un gabarit ou un noyau
B29C 70/76 - Moulage sur les bords ou les extrémités de la partie préformée
B29C 70/84 - Moulage de matière sur des parties préformées à réunir
B29C 70/86 - Incorporation dans des couches de renforcement imprégnées cohérentes
B29C 70/32 - Façonnage par empilage, c.-à-d. application de fibres, de bandes ou de feuilles larges sur un moule, un gabarit ou un noyauFaçonnage par pistolage, c.-à-d. pulvérisation de fibres sur un moule, un gabarit ou un noyau sur un moule, un gabarit ou un noyau rotatifs
B29C 70/38 - Empilage automatisé, p. ex. utilisant des robots, par application de filaments selon des modèles prédéterminés
The invention deals with a method for controlling an orthopedic device, the method comprising the following steps of: - Providing input signals, - Using said input signals as input variables of a musculoskeletal model, - Determining feedback signals using said musculoskeletal model, - Transmitting said feedback signals to said user of said orthopedic device.
The present invention relates to method for cutting and shaping and/or bending a metal element into a final element using laser means, the method comprising providing data containing a final model of the final element and providing a set of instructions as to how to process the final element from the metal element, measure the processing and provide at least a second set of instructions based on feedback, such as geometrical measurements during said processing, so as to create a final element.
G05B 19/4097 - Commande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique caractérisée par l'utilisation de données de conception pour commander des machines à commande numérique [CN], p. ex. conception et fabrication assistées par ordinateur CFAO
59.
A PLANNING METHOD FOR PROCESSING AN ELEMENT INTO A FINAL ELEMENT
The present invention relates to a computer-implemented method for planning laser processing of one or more elements into one or more final elements, such as planning a process of creating a final element from a sheet metal by creating a 5 model of both the sheet metal to be processed and the final element and determining a plurality of processing steps to create said final element. The method is based on a plurality of rules for taking into account, how to process the element by a plurality of processing steps, said processing steps comprising laser process specifications and generating at least a first set of instructions for an 10 associated laser processing device.
G05B 19/4097 - Commande numérique [CN], c.-à-d. machines fonctionnant automatiquement, en particulier machines-outils, p. ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'un programme sous forme numérique caractérisée par l'utilisation de données de conception pour commander des machines à commande numérique [CN], p. ex. conception et fabrication assistées par ordinateur CFAO
60.
NON-INVASIVE FRONT-END FOR POWER ELECTRONIC MONITORING
A front-end device for monitoring operation of an associated electric power device with semiconductor power switches generating a power output, e.g. a three-phase power output. The front-end device has input terminals arranged for connection to the electric phase(s) of the power output of the associated electric power device, and an electric circuit connected to the input terminals and connected to at set of output terminals. The electric circuit has a passive interconnection comprising electric semiconductor switches and diodes. The electric circuit serves to electrically block any high voltage component from the input terminals from reaching the output terminals, while allowing an on-state voltage of at least one semiconductor power switch in the associated electric power device to pass to the at least two output terminals. The front-end allows low voltage equipment to be connected to its output terminals for determining an on-state voltage of switches of the electric power device. Especially, embodiments with self-powered reference voltage circuits provided by zener diodes allow compact low cost versions for use in e.g. portable test equipment or as part of permanently installed health condition monitoring of power devices. The front-end device can be used as a simple and low cost solution for non-invasive health condition monitoring of power devices, e.g. power converters in such as power electric generation system or electric vehicles. Such monitoring allows predictive maintenance to be performed to avoid any faults in the power device that may cause permanent damages.
Existing modular multi-level converters can be bulky because their submodule capacitors are comparatively large. To address this shortcoming in the state of the art, the present disclosure provides electronic power circuits and their use in power converters and in modular multi-level converters. The disclosed power circuits include connection terminals connected to electrically controllable bidirectional two-quadrant switches and to capacitors, as well as inductors that are magnetically coupled and operate to equalize voltages of the capacitors.
H02M 7/483 - Convertisseurs munis de sorties pouvant chacune avoir plus de deux niveaux de tension
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
An active two-terminal inductor device with a controllable inducitance based on an inductance value input L_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value inductor component L1. Based on sampling of at least a voltage or a current in connection with the inductor component L1, the algorithm controls the power converter PCV to provide a resulting inductance across the external terminals A, B which serves to match the inductance value input L_I.
H01F 7/06 - Électro-aimantsActionneurs comportant des électro-aimants
H01F 7/20 - Électro-aimantsActionneurs comportant des électro-aimants sans armature
H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
The invention relates to a hand orthosis (1) for assisting the movements of a user's hand. The hand orthosis comprises a soft glove (2) adapted to receive at least a part of the user's hand with finger sections of the glove receiving each of the user's fingers. It further comprises at least one actuator box (3), and a power transmission (4) for transferring forces from the at least one actuator box to different parts of the glove via exo-tendons (5). The exo-tendons are arranged on a dorsal side, on a palmar side, or on both a dorsal side and a palmar side of the glove. The exo-tendons are arranged so that the glove can assist flexion, extension, or both extension and flexion of the fingers, respectively and so that the exo-tendons act on the fingers to produce motion that mimics the movement of a human hand. The hand orthosis provides different grasp types, self- adaptation of the fingers' motion to the shape of the object, and physiologically appropriate distribution of finger forces.
A61F 5/01 - Dispositifs orthopédiques, p. ex. dispositifs pour immobiliser ou pour exercer des pressions de façon durable pour le traitement des os fracturés ou déformés, tels que éclisses, plâtres orthopédiques ou attelles
An active two-terminal capacitor device with a controllable capacitance based on a capacitance value input C_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value capacitor component CI. Based on sampling of at least the voltage across the capacitor component CI, the algorithm controls the power converter PCV to provide a resulting capacitance across the external terminals A, B which serves to match the capacitance value in ut C_I.
H02M 3/158 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p. ex. régulateurs à commutation comprenant plusieurs dispositifs à semi-conducteurs comme dispositifs de commande finale pour une charge unique
G06F 1/26 - Alimentation en énergie électrique, p. ex. régulation à cet effet
H02M 7/00 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continuTransformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif
H02M 7/5387 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant alternatif sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs, p. ex. onduleurs à impulsions à un seul commutateur dans une configuration en pont
66.
MULTIPARAMETERIC ESTIMATION OF CARDIORESPIRATORY FITNESS IN SEISMOCARDIOGRAPHY
The proposed technology relates to the quantifying of cardiorespiratory fitness. It includes the obtaining (102) of a seismocardiogram (SCG) recorded with an accelerometer (14) configured to measure accelerations and vibrations of the chest wall of a person (18) caused by myocardial movement. Properties of a first signal feature (AC) in the seismocardiogram (SCG) are determined (104), wherein the first signal feature (AC) corresponds to the aortic valve closure (AC) of a heartbeat. A measure indicating cardiorespiratory fitness (VO2max) is then determined (106) based on the properties of first signal feature (AC).
A61B 5/0205 - Évaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p. ex. de l'état cardiaque et respiratoire
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
67.
BIOMARKERS FOR PULMONARY EMBOLISM IN EXHALED BREATH CONDENSATE
REGION NORDJYLLAND, AALBORG UNIVERSITY HOSPITAL (Danemark)
AARHUS UNIVERSITET (Danemark)
AALBORG UNIVERSITET (Danemark)
Inventeur(s)
Gade, Inger, Lise
Honoré, Bent
Kristensen, Søren, Risom
Abrégé
A method is provided for determining pulmonary embolism and/or increased risk thereof in a human being, comprising collecting a sample of exhalation air from said human being and determining the presence or absence in said exhaled air of one or more biomarkers associated with pulmonary embolism. Additionally, a kit that comprises the means for detecting at least one biomarker associated with pulmonary embolism or risk thereof is provided.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
68.
MULTIPARAMETERIC ESTIMATION OF CARDIORESPIRATORY FITNESS IN SEISMOCARDIOGRAPHY
The proposed technology relates to the quantifying of cardiorespiratory fitness. It includes the obtaining (102) of a seismocardiogram (SCG) recorded with an accelerometer (14) configured to measure accelerations and vibrations of the chest wall of a person (18) caused by myocardial movement. Properties of a first signal feature (AC) in the seismocardiogram (SCG) are determined (104), wherein the first signal feature (AC) corresponds to the aortic valve closure (AC) of a heartbeat. A measure indicating cardiorespiratory fitness (VO2max) is then determined (106) based on the properties of first signal feature (AC).
G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p. ex. la physiothérapie, l’acupression ou les exercices
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
69.
Therapeutic targeting of a microRNA to treat Duchenne muscular dystrophy
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61K 31/7115 - Acides nucléiques ou oligonucléotides ayant des bases modifiées, c.-à-d. autres que l'adénine, la guanine, la cytosine, l'uracile ou la thymine
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
A61K 31/711 - Acides désoxyribonucléiques naturels, c.-à-d. contenant uniquement des 2'-désoxyriboses liés à l'adénine, la guanine, la cytosine ou la thymine et ayant des liaisons 3'-5' phosphodiester
70.
SPHERICAL MECHANISM CONSTRUCTED WITH SCISSORS LINKAGES WITH CONTROL MEANS
The invention relates to a curved spherical scissors linkage mechanism (1) comprising at least four linkage elements (2) each having a first end (3) and a second end (4); the linkage elements are arranged to form sides of one rhombus or parallelogram, or a series, such as a network, of joined rhombus or parallelograms. Each of the linkage elements is rotationally connected to one of the other linkage elements via a revolute joint (5) at or near the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at or near the second end. The linkage elements are shaped, dimensioned and arranged so that the axes of all the revolute joints coincide at one common remote centre of motion (RCM). Furthermore, the mechanism is grounded or connected or connectable to a first external member (7) at a proximal end and is rotationally connected or connectable to a second external member (9) at an opposite distal end. Hereby a spherical linkage mechanism with three DOFs is obtained. The spherical scissors linkage mechanism may further comprise a motion controlling mechanism at the proximal and/or at the distal end. It further comprises actuator means as control means.
The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.
The present invention relates to a computer-implemented method for identification of the degree to which a transient disturbance in ventilation causes changes in measurement of arterial acid-base status.
A curved scissor linkage mechanism (1) includes at least four linkage elements (2) each having a first end (3) and a second end (4). The linkage elements are arranged to form sides of one or more rhombi or parallelograms. Each linkage element is rotationally connected to another linkage elements via a revolute joint (5) at the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at the second end. The linkage elements are configured so that the axes of each joint coincide at one common remote centre of motion. The mechanism is connectable to a first external member (7) at a proximal end and is rotationally connectable to a second external member (9) at an opposite distal end to obtain three DOFs. The scissor linkage mechanism may further include a motion controlling mechanism.
F16H 21/54 - Transmissions ne comportant essentiellement que des tringles ou des leviers, avec ou sans glissières avec mouvements dans les trois dimensions pour convertir un mouvement oscillant en mouvement alternatif et vice versa ou pour transmettre ces mouvements
74.
A RECONFIGURABLE COMPLIANT REVOLUTE JOINT MECHANISM WITH NONLINEAR STIFFNESS
The invention is a new design of a compliant revolute joint mechanism, which has multiple configurations exhibiting variable stiffness performance. The joint mechanism provides compliance between its input and output shafts. Variable stiffness performance, such as soft spring, hard spring, in addition to linear spring, can be achieved by changing the mechanism configuration which is based on the wrapping pattern of elastic material, replacing the elastic material of different stiffness, or tuning their pretention force. The invention is designed with a compact structure. The new joint can be integrated into electric motors to build compliant actuators in assistive exoskeletons, rehabilitation robots and other robots where a safe human-robot interaction is concerned. The innovation can also be applied as a new coupling device, which is commonly used in motion transmissions.
F16D 3/62 - Accouplements extensibles, c.-à-d. avec moyens permettant le mouvement entre parties accouplées durant leur entraînement avec pièces d'accouplement reliées par un ou plusieurs organes intermédiaires comportant des tringles de poussée ou de traction reliées à la fois aux deux parties les tringles ou leurs fixations étant élastiques
75.
Integrated end-fire MM-wave antenna array with low frequency metal-framed antenna
The present subject matter relates to antenna systems, devices, and methods that are designed to avoid the degradation of the end-fire radiation pattern of the array when a piece of metal is added obstructing the direction of the main beam. A parasitic radiator is positioned in proximity to the blocking structure and configured to couple at least part of the reflected radiation pattern and radiate toward the desired end-fire direction.
H01Q 21/29 - Combinaisons d'unités d'antennes de types différents interagissant entre elles pour donner une caractéristique directionnelle désirée
H04B 7/06 - Systèmes de diversitéSystèmes à plusieurs antennes, c.-à-d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission
H01Q 1/24 - SupportsMoyens de montage par association structurale avec d'autres équipements ou objets avec appareil récepteur
H01Q 1/36 - Forme structurale pour éléments rayonnants, p. ex. cône, spirale, parapluie
H01Q 5/392 - Combinaison d’éléments alimentés et d’éléments passifs les éléments passifs étant bibandes ou multibandes
H01Q 7/00 - Cadres ayant une distribution du courant sensiblement uniforme et un diagramme de rayonnement directif perpendiculaire au plan du cadre
An electric converter for converting AC or DC input into an electric AC or DC output. A swap circuit with controllable electric switches serves to selectively swap connection of a plurality of DC power banks (DCBs) between an input terminal and an output terminal, thus selectively connecting the DCBs to an electric source or an electric load. The DCBs are formed as series of interconnected submodules (SMs) each having one or more electric energy storage elements (ESEs) and a switching circuit for selectively by-passing or connecting the ESEs. The ESEs can be capacitors, batteries, super capacitors, or a combination of these. By properly controlling the swap circuit and the switching of the SMs, such as by taking into account the dead-time for the electric switches involved, the converter can be used for DC-AC, DC-DC, AC-DC, or AC-AC conversion, allowing multilevel output. It can in some embodiments eliminate the need for an unfolding converter, and the converter provides a rather simple and efficient topology, suitable e.g. for connection of a DC input from a photovoltaic elements to an AC electric grid.
H02M 3/07 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des résistances ou des capacités, p. ex. diviseur de tension utilisant des capacités chargées et déchargées alternativement par des dispositifs à semi-conducteurs avec électrode de commande
H02M 7/483 - Convertisseurs munis de sorties pouvant chacune avoir plus de deux niveaux de tension
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
H02J 3/38 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs
Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides.
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
78.
Method and system for measuring the laxity of a joint of a human or an animal
The invention relates to a method of determining the laxity of a joint (9, 15) of a human (5) or an animal. The method comprises providing at least one patient-specific geometrical model (1) of at least one bone and/or at least one prosthesis comprised by the joint. Known loads are applied to the joint or to a part of the body connected to the joint, and a series of actual images (16) of the joint are obtained while the loads are applied. Then the at least one patient-specific geometrical model (1) is registered onto the actual images (16). Based thereon relative displacement and/or rotation of the at least one bone and/or at least one prosthesis is calculated as a function of the applied loads, and based thereon a measure of the laxity of the joint is determined. The invention further relates to a system for performing such a method and to a computer readable medium for performing such a method.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
The present invention relates to electronic power circuits and their use in power converters and in modular multi-level converters (MMCs) comprising such power converters.
H02M 7/483 - Convertisseurs munis de sorties pouvant chacune avoir plus de deux niveaux de tension
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
The invention relates to a method of controlling thermal stress of a semiconductor chip, the method comprises the steps of: establishing a modular frequency of the semiconductor chip and thereby a thermal profile of the semiconductor chip and establishing a pulsing current controlling the thermal profile of a thermoelectric cooling device thermally connected to the semiconductor chip. Wherein the pulsing current is generated in response to the modular frequency, so that a super cooling period of the thermal profile of the thermoelectric cooling device is at least partly overlapping a temperature increasing period of the thermal profile of the semiconductor chip,anda recovery period of the thermal profile of the thermoelectric cooling device is at least partly overlapping a temperature decreasing period of the thermal profile of the semiconductor chip.
H01L 23/38 - Dispositifs de refroidissement utilisant l'effet Peltier
H01L 35/30 - DISPOSITIFS À SEMI-CONDUCTEURS; DISPOSITIFS ÉLECTRIQUES À L'ÉTAT SOLIDE NON PRÉVUS AILLEURS - Détails fonctionnant exclusivement par effet Peltier ou effet Seebeck caractérisés par les moyens d'échange de chaleur à la jonction
H01L 35/32 - DISPOSITIFS À SEMI-CONDUCTEURS; DISPOSITIFS ÉLECTRIQUES À L'ÉTAT SOLIDE NON PRÉVUS AILLEURS - Détails fonctionnant exclusivement par effet Peltier ou effet Seebeck caractérisés par la structure ou la configuration de la cellule ou du thermocouple constituant le dispositif
81.
GENERATING SOUND ZONES USING VARIABLE SPAN FILTERS
The invention provides a method for generating output filters to a plurality of loudspeakers at respective positions for playback of a plurality of different input signals in respective spatially different sound zones by means of a processor system. The method comprising computing spatio-temporal correlation matrices in response to spatial information, e.g. measured transfer functions, and in response to desired sound pressures in the plurality of sound zones. Joint eigenvalue decomposition of the spatial correlation matrices are then computed, or at least an approximation thereof, to arrive at eigenvectors accordingly. Next, variable span filters a reformed from a linear combination of the eigenvectors in response to a desired trade-off between acoustic contrast and acoustic errors in the sound zones. Finally, output filter for each of the plurality of loudspeakers,for each of the plurality of input signals, in accordance with the variable span filters.The method is applicable also for optimization in one zone, e.g. for room equalization.
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
A61K 31/7115 - Acides nucléiques ou oligonucléotides ayant des bases modifiées, c.-à-d. autres que l'adénine, la guanine, la cytosine, l'uracile ou la thymine
A61K 31/711 - Acides désoxyribonucléiques naturels, c.-à-d. contenant uniquement des 2'-désoxyriboses liés à l'adénine, la guanine, la cytosine ou la thymine et ayant des liaisons 3'-5' phosphodiester
An active two-terminal inductor device with a controllable inducitance based on an inductance value input L_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value inductor component L1. Based on sampling of at least a voltage or a current in connection with the inductor component L1, the algorithm controls the power converter PCV to provide a resulting inductance across the external terminals A, B which serves to match the inductance value input L_I.
H02M 1/15 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu utilisant des éléments actifs
H02J 1/02 - Dispositions pour réduire les harmoniques ou les ondulations
H02J 1/14 - Équilibrage de la charge dans un réseau
H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ
An active two-terminal capacitor device with a controllable capacitance based on a capacitance value input C_I. A processor system PRS executes an algorithm which controls a power converter PCV with controllable electric switches connected to the two external terminals A, B along with a fixed value capacitor component CI. Based on sampling of at least the voltage across the capacitor component CI, the algorithm controls the power converter PCV to provide a resulting capacitance across the external terminals A, B which serves to match the capacitance value in ut C_I.
H02M 1/15 - Dispositions de réduction des ondulations d'une entrée ou d'une sortie en courant continu utilisant des éléments actifs
H02J 1/02 - Dispositions pour réduire les harmoniques ou les ondulations
H02J 1/14 - Équilibrage de la charge dans un réseau
H03K 17/687 - Commutation ou ouverture de porte électronique, c.-à-d. par d'autres moyens que la fermeture et l'ouverture de contacts caractérisée par l'utilisation de composants spécifiés par l'utilisation, comme éléments actifs, de dispositifs à semi-conducteurs les dispositifs étant des transistors à effet de champ
87.
Method and device for analyzing a condition of a heart
A method for analyzing a condition of a heart, comprises receiving a plurality of electric signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p. ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p. ex. oligonucléotides anti-sens
A61K 31/712 - Acides nucléiques ou oligonucléotides ayant des sucres modifiés, c.-à-d. autres que le ribose ou le 2'-désoxyribose
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c.-à-d. autres que des liaisons 3'-5' phosphodiester
A61P 35/02 - Agents anticancéreux spécifiques pour le traitement de la leucémie
A61K 9/127 - Vecteurs à bicouches synthétiques, p. ex. liposomes ou liposomes comportant du cholestérol en tant qu’unique agent tensioactif non phosphatidylique
89.
FUEL CELL ASSEMBLY WITH A TURBULENCE INDUCING DEVICE FOR REDUCTION OF A TEMPERATURE GRADIENT
The present invention relates to an air-cooled fuel cell assembly (9) comprising a fuel cell (1) having a membrane electrode assembly disposed between an anode fluid flow plate and a cathode fluid flow plate, said cathode flow plate defining a flow channel for conveying oxidant to the membrane electrode assembly, said flow channel having an inlet and an outlet and said flow channel extending between two opposing perimeters (5a, 5b) of said fuel cell assembly (9), an air pump (2) arranged to generate air flow in said flow channel in a first direction (8), a turbulence inducing device (4) upstream, relative to said first direction (8), of said flow channel, said turbulence inducing device comprising a grid.
A technology for quantifying, or determining an indication of, cardiorespiratory fitness is disclosed. A signal portion is obtained from a signal recorded with an accelerometer placed on the chest of a person. The accelerometer measures accelerations and vibrations of the chest wall of the person caused by myocardial movement. A maximum value is determined in the signal portion, and output information is provided indicating cardiorespiratory fitness based on the maximum value.
The invention relates to a curved scissor linkage mechanism(1)comprising at least four linkage elements(2)each having a first end (3) and a second end(4); the linkage elements are arranged to form sides of one rhombus or parallelogram, or a series, such as a network, of joined rhombi or parallelograms. Each of the linkage elements is rotationally connected to one of the other linkage elements via a revolute joint (5) at or near the first end and is rotationally connected to another one of the other linkage elements via another revolute joint at or near the second end. The linkage elements are shaped, dimensioned and arranged so that the axes of all the revolute joints coincide at one common remote centre of motion(RCM). Furthermore, the mechanism is grounded or connected or connectable to a first external member (7) at a proximal end and is rotationally connected or connectable to a second external member (9) at an opposite distal end. Hereby a spherical linkage mechanism with three DOFs is obtained. The scissor linkage mechanism may further comprise a motion controlling mechanism at the proximal and/or at the distal end.
E04H 15/50 - Moyens de support, p. ex. armatures repliables, p. ex. du type démontable pliables, c.-à-d. avec des charnières ou des gonds du type à ciseaux
92.
Accelerated processing for maximum distance separable codes using composite field extensions
Disclosed apparatus and method improve the computational efficiency of encoding and decoding data having erasures according to a maximum distance separable (MDS) code based on a Reed-Solomon code. Thus, n encoded fragments are formed by multiplying k data fragments by an n×k generator matrix for the MDS code. The code is formed by reducing, in the generator matrix to the extent possible, the size of the finite field to which entries belong—in some cases to the base field having only two elements. In this way, unlike codes known in the art, the generator matrix has more than one column whose entries each take values in the finite field having two elements. In some cases, the generator matrix has a column whose entries each take values in one or more intermediate fields between the finite field having two elements and the encoding field.
H03M 13/00 - Codage, décodage ou conversion de code pour détecter ou corriger des erreursHypothèses de base sur la théorie du codageLimites de codageMéthodes d'évaluation de la probabilité d'erreurModèles de canauxSimulation ou test des codes
H03M 13/37 - Méthodes ou techniques de décodage non spécifiques à un type particulier de codage prévu dans les groupes
G06F 9/30 - Dispositions pour exécuter des instructions machines, p. ex. décodage d'instructions
H03M 13/15 - Codes cycliques, c.-à-d. décalages cycliques de mots de code produisant d'autres mots de code, p. ex. codes définis par un générateur polynomial, codes de Bose-Chaudhuri-Hocquenghen [BCH]
G06F 7/72 - Méthodes ou dispositions pour effectuer des calculs en utilisant une représentation numérique non codée, c.-à-d. une représentation de nombres sans baseDispositifs de calcul utilisant une combinaison de représentations de nombres codées et non codées utilisant l'arithmétique des résidus
93.
Method and apparatus to enhance routing protocols in wireless mesh networks
A protocol for use in wireless mesh networks uses helper nodes to improve data flow in the network. The protocol is compatible with traditional mesh network routing algorithms. Techniques, systems, devices, and circuits for implementing the protocol are described.
H04W 40/12 - Sélection d'itinéraire ou de voie de communication, p. ex. routage basé sur l'énergie disponible ou le chemin le plus court sur la base de la qualité d'émission ou de la qualité des canaux
The present invention relates to a method for extracting cannabinoids from cannabis plant material using an extractor with super critical carbon dioxide. The process comprises the steps of: a) providing a cannabis plant material with a water content of at most 60% w/w, preferably at most 10% w/w; b1) in a pressure tank, subjecting the cannabis plant material to a first extraction step with a one-phase solvent system comprising supercritical carbon dioxide and optionally a non-polar co-solvent, and performed at a temperature of about 30-60 degrees Celsius; c1) collecting a first liquid extract from the pressure tank; d) collecting/removing a solid product from the pressure tank comprising a cannabis plant fiber material with a reduced content of cannabinoids; e) dissolving the first liquid extract from the pressure tank in ethanol, subjecting the solution to one or more winterization steps, filtrating the solution to remove precipitated matter, and removing the ethanol to collect a second liquid extract; f) optionally, heat treating the second liquid extract at 100-150 degrees Celsius to decarboxylate any acid form of the cannabinoids to the neutral form of the cannabinoids; g) dissolving the second liquid extract, optionally heat treated, in a non-polar solvent; h) extracting the solubilized second liquid extract with an aqueous basic solution; and collecting the non-polar solvent phase as a third liquid extract; and i) optionally, removing the non-polar solvent to collect the neutral form of the cannabinoids.
The invention relates to a method of diagnosing a migraine and/or migraine attack, the method in a subject comprising determining a change in the expression level of a biological marker in the biological sample. Preferably, the method is the in vitro method.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
96.
METHOD AND SYSTEM FOR MEASURING THE LAXITY OF A JOINT OF A HUMAN OR AN ANIMAL
The invention relates to a method of determining the laxity of a joint (9, 15) of a human (5) or an animal. The method comprises providing at least one patient-specific geometrical model (1) of at least one bone and/or at least one prosthesis comprised by the joint. Known loads are applied to the joint or to a part of the body connected to the joint, and a series of actual images (16) of the joint are obtained while the loads are applied. Then the at least one patient-specific geometrical model (1) is registered onto the actual images (16). Based thereon relative displacement and/or rotation of the at least one bone and/or at least one prosthesis is calculated as a function of the applied loads, and based thereon a measure of the laxity of the joint is determined. The invention further relates to a system for performing such a method and to a computer readable medium for performing such a method.
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p. ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiquesMesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p. ex. formation d'images par résonance magnétique
A61B 5/107 - Mesure de dimensions corporelles, p. ex. la taille du corps entier ou de parties de celui-ci
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
REGION NORDJYLLAND, AALBORG UNIVERSITY HOSPITAL (Danemark)
AALBORG UNIVERSITET (Danemark)
Inventeur(s)
Thorlacius-Ussing, Ole
Ladefoged Rasmussen, Simon
Bygum Krarup, Henrik
Madsen, Poul Henning
Abrégé
A method is provided for determining colorectal cancer, or the prognosis of a colorectal cancer in a subject, said method comprising in a sample from said subject determining the methylation status of a specific gene marker panel.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des acides nucléiques
98.
JUNCTION TEMPERATURE MEASUREMENT IN A POWER SEMICONDUCTOR MODULE
A method for determining the temperature of a power semiconductor, where the power semiconductor includes an auxiliary emitter terminal and an emitter terminal, and a resistance component arranged between. The resistance component is thermally coupled and/or integrated into the semiconductor die. The resistance component is arranged between the auxiliary emitter terminal and the emitter terminal, and lies in the path of the control current. The resistance component has a temperature dependent resistance characteristic. A measurement circuit is used to inject a sufficient sensing current, or apply a suitable voltage, to the resistance component between the auxiliary emitter and emitter terminals, in order to generate an output signal that is dependent on the temperature dependent resistance of the resistance component. The output signal can be assessed with respect to a predefined temperature characteristic curve, obtained through a calibration procedure. Thus, the temperature of the semiconductor is measured.
G01K 7/16 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs
99.
METHOD AND DEVICE FOR ANALYZING A CONDITION OF A HEART
A method for analyzing a condition of a heart, comprises receiving a plurality of electrical signals, which are acquired by non-invasive measurement on the skin of a person or animal, each signal representing electrical activity in a respective region of the heart of the person or animal; calculating a derivative value of each signal at a plurality of time instances; selecting a plurality of the calculated derivative values of a first signal and determining a first point in time of a first event based on the selected derivative values; selecting a plurality of the calculated derivative values of a second signal and determining a second point in time of a second event, corresponding to the first event, based on the selected derivative values of the second signal, and calculating at least one measure based on a difference of the first point in time and the second point in time.