Systems and methods are disclosed for dynamic radiotherapy treatment planning in a continuous space of computation. Example operations for generating treatment plan data for a radiotherapy treatment include: obtaining data for a radiotherapy treatment of a human subject; generating a set of radiation controls from the data for the radiotherapy treatment, with at least one of the radiation controls being based on a mapping from a continuous (e.g., infinite dimensional) computational space; converting the generated set of radiation controls to a set of treatment delivery parameters, the set of treatment delivery parameters corresponding to capabilities of a radiotherapy treatment machine; and producing treatment plan data for the radiotherapy treatment based on the set of treatment delivery parameters.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for the generation, capture, analysis and
display of medical images including X-ray images, magnetic
resonance imaging [MRI], computed tomography [CT], CBCT
[cone beam computed tomography] images, ultrasound images,
PET [positron emission tomography] images, SPECT/CT [single
photon emission computed tomography] images; software for
processing images; software for treatment planning and
workflow; software for measuring and analyzing radiation
dose delivery in radiosurgery and radiotherapy equipment. Software as a service, for use in the following fields:
medicated treatments and planning and simulation of medical
treatment; software as a service for handling, displaying
and transfer of patient data, information and images;
software as a service [SaaS] for the creation, collection,
analysis, processing and display of medical images; software
as a service for medical analytics and informatics.
Systems and methods are disclosed for simulating dose deposition. The systems and methods perform operations comprising: receiving a set of training data representing phase space of a radiotherapy treatment device comprising propagation and scattering of particles inside the radiotherapy treatment device; training a generative machine learning model based on the set of training data to generate one or more samples of the phase space of the radiotherapy treatment device; and simulating dose deposition at a particular region of interest based on the one or more samples of the phase space generated by the generative machine learning model.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Computer software for the generation, capture, analysis and display of medical images including X-ray images, magnetic resonance imaging [MRI], computed tomography [CT], CBCT [cone beam computed tomography] images, ultrasound images, PET [positron emission tomography] images, SPECT/CT [single photon emission computed tomography] images; software for processing images; software for treatment planning and workflow; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment. (1) Software as a service, for use in the following fields: medicated treatments and planning and simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; software as a service [SaaS] for the creation, collection, analysis, processing and display of medical images; software as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable computer software for the generation, capture, analysis and display of medical images in particular x-rays, magnetic resonance images, computed tomography images, cone beam computed tomography images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images; downloadable software for processing images; downloadable medical treatment planning and workflow software; downloadable software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment Software as a service (SaaS) services featuring software for use in medicated treatments and planning and simulation of medical treatment; software as a service (SaaS) services featuring software for handling, displaying and transfer of patient data, information and images; software as service (SaaS) services featuring software for creation, collection, analysis, processing and display of medical images; software as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, magnetic resonance
images (MR), computed tomography images (CT), cone beam
computed tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
the calculation of dose planning and flow charts and for
display during radiotherapy; computer software for managing
medical systems and devices; software for processing images;
computer software for data analytics; linear accelerator
management and control software; medical database software;
treatment planning and workflow software; software for cloud
based services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form recorded or downloadable from a
computer network or the internet; electronic magazines;
remote software applications; hardware and software for
quality assurance and calibration measurements in medical
and surgical equipment; optical receivers; optical
transmitters. Medical and surgical apparatus and instruments; apparatus
and instruments for use with medical analysis for
identification, planning as well as implementing of
treatment against cancer, benign diseases or neurological
disorders using radiation; radiosurgery and radiotherapy
equipment, apparatus and instruments; image guided radiation
therapy device for use in medicine and computer software and
hardware sold as a unit therewith; testing apparatus for
medical purposes; radiological apparatus for medical
purposes; collimators for medical purposes; fasteners
adapted for the restraining of limbs during measurement and
treatment; medical and radiographic linear accelerators;
radiation beam collimation apparatus for radiotherapy;
magnetoencephalography medical imaging equipment;
radiographic and X-ray medical apparatus; X-ray tubes for
medical purposes; X-ray medical imaging tubes for radiation;
radiation delivery devices, for medical purposes; X-ray
image intensifiers, for medical purposes; accelerators for
charged particles for therapeutic purposes; medical imaging
apparatus for the creation or transmission of images, video
or data relating to a medical treatment for diagnostic or
clinical use; surgical tables, beds and armchairs,
treatment, medical-care and operating tables, beds and
armchairs; furniture especially made for medical purposes;
medical instruments, equipment and apparatus, in relation to
the following fields: manipulation and positioning of
patients; patient safety restraints; imaging and treatment
simulation apparatus for treatment planning and simulation;
medical imaging apparatus; X-ray radiographic and
fluoroscopic imaging systems for medical purposes; parts and
fittings for the above.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, magnetic resonance images (MR), computed tomography images (CT), cone beam computed tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); computer software for the calculation of dose planning and flow charts and for display during radiotherapy; computer software for managing medical systems and devices; software for processing images; computer software for data analytics; linear accelerator management and control software; medical database software; treatment planning and workflow software; software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form recorded or downloadable from a computer network or the internet; electronic magazines; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; optical receivers; optical transmitters.
(2) Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; testing apparatus for medical purposes; radiological apparatus for medical purposes; collimators for medical purposes; fasteners adapted for the restraining of limbs during measurement and treatment; medical and radiographic linear accelerators; radiation beam collimation apparatus for radiotherapy; magnetoencephalography medical imaging equipment; radiographic and X-ray medical apparatus; X-ray tubes for medical purposes; X-ray medical imaging tubes for radiation; radiation delivery devices, for medical purposes; X-ray image intensifiers, for medical purposes; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgical tables, beds and armchairs, treatment, medical-care and operating tables, beds and armchairs; furniture especially made for medical purposes; medical instruments, equipment and apparatus, in relation to the following fields: manipulation and positioning of patients; patient safety restraints; imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging apparatus; X-ray radiographic and fluoroscopic imaging systems for medical purposes; parts and fittings for the above.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, magnetic resonance images (MR), computed tomography images (CT), cone beam computed tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); computer software for the calculation of dose planning and flow charts and for display during radiotherapy; computer software for managing medical systems and devices; software for processing images; computer software for data analytics; linear accelerator management and control software; medical database software; treatment planning and workflow software; software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form recorded or downloadable from a computer network or the internet; electronic magazines; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; optical receivers; optical transmitters. Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; testing apparatus for medical purposes; radiological apparatus for medical purposes; collimators for medical purposes; fasteners adapted for the restraining of limbs during measurement and treatment; medical and radiographic linear accelerators; radiation beam collimation apparatus for radiotherapy; magnetoencephalography medical imaging equipment; radiographic and X-ray medical apparatus; X-ray tubes for medical purposes; X-ray medical imaging tubes for radiation; radiation delivery devices, for medical purposes; X-ray image intensifiers, for medical purposes; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgical tables, beds and armchairs, treatment, medical-care and operating tables, beds and armchairs; furniture especially made for medical purposes; medical instruments, equipment and apparatus, in relation to the following fields: manipulation and positioning of patients; patient safety restraints; imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging apparatus; X-ray radiographic and fluoroscopic imaging systems for medical purposes; parts and fittings for the above.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for the generation, capture, analysis and display of medical images including X-ray images, magnetic resonance imaging [MRI], computed tomography [CT], CBCT [cone beam computed tomography] images, ultrasound images, PET [positron emission tomography] images, SPECT/CT [single photon emission computed tomography] images; Software for processing images; Software for treatment planning and workflow; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment. Software as a service, for use in the following fields: medicated treatments and Planning and simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; Software as a service [SaaS] for the creation, collection, analysis, processing and display of medical images; Software as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for the calculation of dose planning and flow charts and for display during radiotherapy; Computer software for managing medical systems and devices; Software for processing images; computer software for data analytics; Linear accelerator management and control software; medical database software; treatment planning and workflow software; Software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; Quality assurance software; Calibration software; Software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; Electronic magazines; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; Optical receivers; Optical transmitters. Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; Testing apparatus for medical purposes; Radiological apparatus for medical purposes; collimators for medical purposes; Fasteners for the restraining of limbs during measurement and treatment; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; Radiographic and x-ray equipment; x-ray tubes; X-ray imaging tubes for radiation; Radiation delivery devices, for medical purposes; X-ray image intensifiers, for medical purposes; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; Surgical tables, beds and armchairs, treatment, medical-care and operating tables, beds and armchairs; Furniture especially made for medical purposes; Medical instruments, Equipment and Apparatus, in relation to the following fields: Manipulation and positioning of patients; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; Medical imaging apparatus; X-ray radiographic and fluoroscopic imaging systems for medical purposes; parts and fittings for the above.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, magnetic resonance
images (MR), computed tomography images (CT), cone beam
computed tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
the calculation of dose planning and flow charts and for
display during radiotherapy; computer software for managing
medical systems and devices; software for processing images;
computer software for data analytics; linear accelerator
management and control software; MRI management and control
software and analytics software; medical database software;
treatment planning and workflow software; software for cloud
based services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form or downloadable from a computer
network or the internet; remote software applications;
hardware and software for quality assurance and calibration
measurements in medical and surgical equipment; computer
software for analysing medical data, software for extracting
medical data; software for compiling medical data, medical
data aggregation software; computer software for remote
access and secure access and reconciliation of medical data
on portable devices and for remote treatment planning,
treatment review and treatment delivery; computer software
for medical treatment quality assurance, treatment planning,
medical treatment assessment and review and medical
technology performance; voice recognition software for
medical equipment, records management, workflow management
and treatment planning. Design and development of computer hardware and software;
computer programming; updating of computer software; remote
software and data hosting services; cloud computing;
electronic data storage and off-site data backup; designing
and development of medical equipment; installation,
maintenance and repair of software for computer systems;
computer software technical support services; computer
software consultancy; medical software planning and
installation services; treatment room design and planning
services for medical and radiotherapy systems; software as a
service for or use in medical treatment as well as with
planning or simulation of medical treatment; software as a
service for handling, displaying and transfer of patient
data, information and images; software as service for
collecting analyzing and displaying medical images; software
as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, magnetic resonance
images (MR), computed tomography images (CT), cone beam
computed tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
the calculation of dose planning and flow charts and for
display during radiotherapy; computer software for managing
medical systems and devices; software for processing images;
computer software for data analytics; linear accelerator
management and control software; MRI management and control
software and analytics software; medical database software;
treatment planning and workflow software; software for cloud
based services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form or downloadable from a computer
network or the internet; remote software applications;
hardware and software for quality assurance and calibration
measurements in medical and surgical equipment; computer
software for analysing medical data, software for extracting
medical data; software for compiling medical data, medical
data aggregation software; computer software for remote
access and secure access and reconciliation of medical data
on portable devices and for remote treatment planning,
treatment review and treatment delivery; computer software
for medical treatment quality assurance, treatment planning,
medical treatment assessment and review and medical
technology performance; voice recognition software for
medical equipment, records management, workflow management
and treatment planning. Design and development of computer hardware and software;
computer programming; updating of computer software; remote
software and data hosting services; cloud computing;
electronic data storage and off-site data backup; designing
and development of medical equipment; installation,
maintenance and repair of software for computer systems;
computer software technical support services; computer
software consultancy; medical software planning and
installation services; treatment room design and planning
services for medical and radiotherapy systems; software as a
service for or use in medical treatment as well as with
planning or simulation of medical treatment; software as a
service for handling, displaying and transfer of patient
data, information and images; software as service for
collecting analyzing and displaying medical images; software
as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, magnetic resonance images (MR), computed tomography images (CT), cone beam computed tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); computer software for the calculation of dose planning and flow charts and for display during radiotherapy; computer software for managing medical systems and devices; software for processing images; computer software for data analytics; linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the internet; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; computer software for analysing medical data, software for extracting medical data; software for compiling medical data, medical data aggregation software; computer software for remote access and secure access and reconciliation of medical data on portable devices and for remote treatment planning, treatment review and treatment delivery; computer software for medical treatment quality assurance, treatment planning, medical treatment assessment and review and medical technology performance; voice recognition software for medical equipment, records management, workflow management and treatment planning; all the aforesaid goods only for use in the field of oncology and radiation therapy for medical treatment. (1) Design and development of computer hardware and software; computer programming; updating of computer software; remote software and data hosting services; cloud computing; electronic data storage and off-site data backup; designing and development of medical equipment; installation, maintenance and repair of software for computer systems; computer software technical support services; computer software consultancy; medical software planning and installation services; treatment room design and planning services for medical and radiotherapy systems; software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; software as service for collecting analyzing and displaying medical images; software as a service for medical analytics and informatics; all the aforesaid services only for use in the field of oncology and radiation therapy for medical treatment.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, magnetic resonance images (MR), computed tomography images (CT), cone beam computed tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); computer software for the calculation of dose planning and flow charts and for display during radiotherapy; computer software for managing medical systems and devices; software for processing images; computer software for data analytics; linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the internet; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; computer software for analysing medical data, software for extracting medical data; software for compiling medical data, medical data aggregation software; computer software for remote access and secure access and reconciliation of medical data on portable devices and for remote treatment planning, treatment review and treatment delivery; computer software for medical treatment quality assurance, treatment planning, medical treatment assessment and review and medical technology performance; voice recognition software for medical equipment, records management, workflow management and treatment planning. (1) Design and development of computer hardware and software; computer programming; updating of computer software; remote software and data hosting services; cloud computing; electronic data storage and off-site data backup; designing and development of medical equipment; installation, maintenance and repair of software for computer systems; computer software technical support services; computer software consultancy; medical software planning and installation services; treatment room design and planning services for medical and radiotherapy systems; software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; software as service for collecting analyzing and displaying medical images; software as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable computer software for use with rendering medical diagnoses as well as with planning or simulation of medical treatment; Downloadable computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; Downloadable computer software for the generation, capture, analysis and display of medical images in particular X-rays, magnetic resonance images, computed tomography images, cone beam computed tomography images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images; Downloadable computer software for the calculation of dose planning and flow charts and for display during radiotherapy; Downloadable computer software for managing medical systems and devices; Downloadable software for processing images; Downloadable computer software for use in performing data analytics; Downloadable linear accelerator management and control software; Downloadable MRI management and control software and analytics software; Downloadable medical database management software; Downloadable medical treatment planning and workflow software; Downloadable software for use in performing cloud based services, data analytics and informatics; Downloadable software for allowing user remote access through wireless connectivity; Downloadable software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; Downloadable quality control assurance software; Downloadable device calibration software; Downloadable software and computerized systems program for use in the management of clinical information and patient data, management of treatment delivery, patient record archiving and clinical charting; data and databases in the field of medicine all recorded electronically, magnetically or optically; user, training and instruction manuals for the operation of the aforesaid goods, all provided recorded on electronic media and downloadable from a computer network or the internet; Downloadable remote user access software applications; Computer hardware and downloadable software for quality assurance and calibration measurements in medical and surgical equipment; Downloadable computer software for analysing medical data; Downloadable software for extracting medical data; Downloadable software for compiling medical data; Downloadable medical data aggregation software; Downloadable computer software for allowing user remote and secure access and reconciliation of medical data on portable devices and for remote treatment planning, treatment review and assistance in treatment delivery; Downloadable computer software for medical treatment quality assurance, treatment planning, medical treatment assessment and review and assessing medical technology performance; Downloadable voice recognition software for operating medical equipment, patient records management, workflow management and medical treatment planning Design and development of computer hardware and software; computer programming; updating of computer software; design and development of remote software; data server hosting services; cloud computing consulting services; electronic data storage and off-site data backup; designing and development of medical equipment; installation, maintenance and repair of software for computer systems; computer software technical support services, namely, troubleshooting of computer software problems; computer software consultancy; medical software design and development and installation services; treatment room interior design and computer hardware design and development services for medical and radiotherapy systems; software as a service (SaaS) services featuring software for use in rendering medical treatment as well as with planning or simulation of medical treatment; software as a service (SaaS) services featuring software for handling, displaying and transfer of patient data, information and images; software as service (SaaS) services featuring software for collecting analyzing and displaying medical images; software as a service (SaaS) services featuring software for use in performing medical analytics and informatics
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for the calculation of dose planning and flow charts and for display during radiotherapy; Computer software for managing medical systems and devices; Software for processing images; computer software for data analytics; Linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; Software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; Quality assurance software; Calibration software; Software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; Computer software for analysing medical data, Software for extracting medical data; Software for compiling medical data, Medical data aggregation software; Computer software for remote access and secure access and reconciliation of medical data on portable devices and for remote treatment planning, treatment review and treatment delivery; Computer software for medical treatment quality assurance, treatment planning, medical treatment assessment and review and medical technology performance; Voice recognition software for medical equipment, records management, workflow management and treatment planning; all the aforesaid goods only for use in the field of oncology and radiation therapy for medical treatment. Design and development of computer hardware and software; Computer programming; Updating of computer software; remote software and data hosting services; Cloud computing; Electronic data storage and off-site data backup; designing and development of medical equipment; Installation, maintenance and repair of software for computer systems; Computer software technical support services; Computer software consultancy; Medical software planning and installation services; Treatment room design and planning services for medical and radiotherapy systems; Software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; Software as service for collecting analyzing and displaying medical images; Software as a service for medical analytics and informatics; all the aforesaid services only for use in the field of oncology and radiation therapy for medical treatment.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for the calculation of dose planning and flow charts and for display during radiotherapy; Computer software for managing medical systems and devices; Software for processing images; computer software for data analytics; Linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; Software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; Quality assurance software; Calibration software; Software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; Electronic publications, downloadable; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment; Medical data extraction and analysis software; Software for compiling medical data, Medical data aggregation software; Computer software for remote access and secure access and reconciliation of medical data on portable devices and for remote treatment planning, treatment review and treatment delivery; Computer software for medical treatment quality assurance, treatment planning, medical treatment assessment and review and medical technology performance; Voice recognition software for medical equipment, records management, workflow management and treatment planning. Design and development of computer hardware and software; Computer programming; Updating of computer software; remote software and data hosting services; Cloud computing; Electronic data storage at another location and off-site back up of data; designing and development of medical equipment; Installation, maintenance and repair of software for computer systems; Computer software technical support services; Computer software consultancy; Medical software planning and installation services; Treatment room design and planning services for medical and radiotherapy systems; Software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; Software as service for collecting analyzing and displaying medical images; Software as a service for medical analytics and informatics.
Systems and methods are disclosed for dynamic radiotherapy treatment planning in a continuous space of computation. Example operations for generating treatment plan data for a radiotherapy treatment include: obtaining data for a radiotherapy treatment of a human subject; generating a set of radiation controls from the data for the radiotherapy treatment, with at least one of the radiation controls being based on a mapping from a continuous (e.g., infinite dimensional) computational space; converting the generated set of radiation controls to a set of treatment delivery parameters, the set of treatment delivery parameters corresponding to capabilities of a radiotherapy treatment machine; and producing treatment plan data for the radiotherapy treatment based on the set of treatment delivery parameters.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Systems and methods are disclosed for estimating optimization problem preferences. The systems and methods perform operations comprising receiving a first set of radiotherapy treatment plan data; processing the first set of radiotherapy treatment plan data with a machine learning model to estimate one or more preferences in a multicriteria radiotherapy treatment plan optimization (MCO) problem, wherein the machine learning model is trained to establish a relationship between the one or more preferences and information associated with a plurality of training radiotherapy treatment plan data, wherein the machine learning model includes a neural network; generating a solution to the MCO problem based on the estimated one or more preferences; and generating a radiotherapy treatment device parameter based on the solution to the MCO problem.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Systems and methods are disclosed for simulating dose deposition. The systems and methods perform operations comprising: receiving a set of training data representing phase space of a radiotherapy treatment device comprising propagation and scattering of particles inside the radiotherapy treatment device; training a generative machine learning model based on the set of training data to generate one or more samples of the phase space of the radiotherapy treatment device; and simulating dose deposition at a particular region of interest based on the one or more samples of the phase space generated by the generative machine learning model.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include operations comprising: obtaining, during delivery of a radiotherapy treatment fraction to a patient, one or more images of the patient at a first rate; generating patient motion information at a second rate based on the one or more images obtained at the first rate; receiving, during delivery of the radiotherapy treatment fraction, radiotherapy treatment device settings at a third rate; computing, during delivery of the radiotherapy treatment fraction, dose delivered to the patient with a first level of accuracy based on the generated patient motion information and the radiotherapy treatment device settings; and determining, during delivery of the radiotherapy treatment fraction, a real-time measure of accumulated dose delivered to the patient with a second greater level of accuracy than the first level of accuracy using one or more prior dose computations.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
24.
Radiotherapy plan parameters with privacy guarantees
Techniques for producing segmentation with privacy are provided. The techniques include receiving a medical image; processing the medical image with a student machine learning model to estimate radiotherapy plan parameters, the student machine learning model being trained to establish a relationship between a plurality of public training medical images and corresponding radiotherapy plan parameters, the radiotherapy plan parameters of the plurality of public training medical images being generated by aggregating a plurality of radiotherapy plan parameter estimates produced by: processing the plurality of public training medical images with a plurality of teacher machine learning models to generate sets of radiotherapy plan parameter estimates; and reducing respective dimensions of the sets of radiotherapy plan parameter estimates or medical images, the radiotherapy plan parameters of the plurality of public training medical images being perturbed in accordance with privacy criteria; and generating a radiotherapy treatment plan based on the estimated radiotherapy plan parameters.
G06F 21/62 - Protecting access to data via a platform, e.g. using keys or access control rules
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
25.
PARAMETER SEARCH IN RADIOTHERAPY TREATMENT PLAN OPTIMIZATION
Techniques for generating a radiotherapy treatment plan are provided. The techniques include receiving a radiotherapy optimization problem, the radiotherapy problem comprising a plurality of parameters; processing the radiotherapy optimization problem to instantiate a first set of candidate parameters; converting the first set of candidate parameters into an adapted representation; defining an adapted radiotherapy optimization problem as a function of the adapted representation such that a given solution to the adapted optimization problem estimates a solution to the radiotherapy optimization problem; processing the adapted radiotherapy optimization problem to estimate a function of the solution to the adapted radiotherapy optimization problem; and processing the estimated function of the solution to the adapted optimization problem to generate a deliverable radiotherapy treatment plan.
Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include retrieving a reference plan that includes three-dimensional (3D) volume representation of information for the patient and a plurality of radiotherapy beam delivery segments; identifying a first portion of the 3D volume representation of information for a first beam delivery segment of the plurality of radiotherapy beam delivery segments that includes a volumetric portion of a target irradiated by the first beam delivery segment; accessing a deformation model representing patient deformation during a radiotherapy treatment fraction; deforming the first portion of the 3D volume representation of information based on the deformation model; and updating one or more parameters of a radiotherapy treatment device based on the deformed first portion of the 3D volume representation of information.
Techniques for generating a radiotherapy treatment plan parameter are provided. The techniques include receiving radiotherapy treatment plan information; processing the radiotherapy treatment plan information to estimate one or more radiotherapy treatment plan parameters based on a process that depends on the output of a subprocess that estimates a derivative of a dose calculation; and generating a radiotherapy treatment plan using the estimated one or more radiotherapy treatment plan parameters.
Systems and methods are provided for radiation delivery. An exemplary method includes receiving an image depicting anatomical data of a target region of patient tissue and determining an initial prescribed dose of radiotherapeutic radiation to be delivered to the target region. The method also includes discretizing the arc for VMAT into a plurality of arc segments and performing an iteration process for determining an arc dose according to radiation delivered in the arc segments. The method further includes determining whether a condition for terminating the iteration process is met and terminating the iteration process based on a result of the determination that the condition for terminating the iteration process is met.
Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include operations comprising: obtaining, during delivery of a radiotherapy treatment fraction to a patient, one or more images of the patient at a first rate; generating patient motion information at a second rate based on the one or more images obtained at the first rate; receiving, during delivery of the radiotherapy treatment fraction, radiotherapy treatment device settings at a third rate; computing, during delivery of the radiotherapy treatment fraction, dose delivered to the patient with a first level of accuracy based on the generated patient motion information and the radiotherapy treatment device settings; and determining, during delivery of the radiotherapy treatment fraction, a real-time measure of accumulated dose delivered to the patient with a second greater level of accuracy than the first level of accuracy using one or more prior dose computations.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
30.
Parameter search in radiotherapy treatment plan optimization
Techniques for generating a radiotherapy treatment plan are provided. The techniques include receiving a radiotherapy optimization problem, the radiotherapy problem comprising a plurality of parameters; processing the radiotherapy optimization problem to instantiate a first set of candidate parameters; converting the first set of candidate parameters into an adapted representation; defining an adapted radiotherapy optimization problem as a function of the adapted representation such that a given solution to the adapted optimization problem estimates a solution to the radiotherapy optimization problem; processing the adapted radiotherapy optimization problem to estimate a function of the solution to the adapted radiotherapy optimization problem; and processing the estimated function of the solution to the adapted optimization problem to generate a deliverable radiotherapy treatment plan.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
+, then the steps previously carried out separately can be combined into a single optimisation. This yields advantages in terms of computational load and in the accuracy of the end result.
Techniques for generating a radiotherapy treatment plan parameter are provided. The techniques include receiving radiotherapy treatment plan information; processing the radiotherapy treatment plan information to estimate one or more radiotherapy treatment plan parameters based on a process that depends on the output of a subprocess that estimates a derivative of a dose calculation; and generating a radiotherapy treatment plan using the estimated one or more radiotherapy treatment plan parameters.
Techniques for solving a radiotherapy treatment plan optimization problem are provided. The techniques include receiving a first radiotherapy treatment plan optimization problem having a first set of parameters; processing the first set of parameters to estimate a second set of parameters of a second radiotherapy treatment plan optimization problem; generating a solution to the second radiotherapy treatment plan optimization problem based on the estimated second set of parameters; and generating a radiotherapy treatment plan based on the solution to the second radiotherapy treatment plan optimization problem.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
34.
Radiotherapy treatment plan optimization using machine learning
Techniques for solving a radiotherapy treatment plan optimization problem are provided. The techniques include receiving a radiotherapy treatment plan optimization problem; processing the radiotherapy treatment plan optimization problem with a machine learning model to estimate one or more optimization variables of the radiotherapy treatment plan optimization problem, wherein the machine learning model is trained to establish a relationship between the one or more optimization variables and parameters of a plurality of training radiotherapy treatment plan optimization problems; and generating a solution to the radiotherapy treatment plan optimization problem based on the estimated one or more optimization variables of the radiotherapy treatment plan optimization problem.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Techniques for generating a radiotherapy treatment plan parameter are provided. The techniques include receiving radiotherapy treatment plan information; processing the radiotherapy treatment plan information to estimate one or more radiotherapy treatment plan parameters based on a process that depends on the output of a subprocess that estimates a derivative of a dose calculation; and generating a radiotherapy treatment plan using the estimated one or more radiotherapy treatment plan parameters.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
Techniques for solving a radiotherapy treatment plan optimization problem are provided. The techniques include receiving a radiotherapy treatment plan optimization problem; processing the radiotherapy treatment plan optimization problem with a machine learning model to estimate one or more optimization variables of the radiotherapy treatment plan optimization problem, wherein the machine learning model is trained to establish a relationship between the one or more optimization variables and parameters of a plurality of training radiotherapy treatment plan optimization problems; and generating a solution to the radiotherapy treatment plan optimization problem based on the estimated one or more optimization variables of the radiotherapy treatment plan optimization problem.
Techniques for solving a radiotherapy treatment plan optimization problem are provided. The techniques include receiving a first radiotherapy treatment plan optimization problem having a first set of parameters; processing the first set of parameters to estimate a second set of parameters of a second radiotherapy treatment plan optimization problem; generating a solution to the second radiotherapy treatment plan optimization problem based on the estimated second set of parameters; and generating a radiotherapy treatment plan based on the solution to the second radiotherapy treatment plan optimization problem.
Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include retrieving a reference plan that includes three- dimensional (3D) volume representation of information for the patient and a plurality of radiotherapy beam delivery segments; identifying a first portion of the 3D volume representation of information for a first beam delivery segment of the plurality of radiotherapy beam delivery segments that includes a volumetric portion of a target irradiated by the first beam delivery segment; accessing a deformation model representing patient deformation during a radiotherapy treatment fraction; deforming the first portion of the 3D volume representation of information based on the deformation model; and updating one or more parameters of a radiotherapy treatment device based on the deformed first portion of the 3D volume representation of information.
Techniques for producing segmentation with privacy are provided. The techniques include receiving a medical image; processing the medical image with a student machine learning model to estimate radiotherapy plan parameters, the student machine learning model being trained to establish a relationship between a plurality of public training medical images and corresponding radiotherapy plan parameters, the radiotherapy plan parameters of the plurality of public training medical images being generated by aggregating a plurality of radiotherapy plan parameter estimates produced by: processing the plurality of public training medical images with a plurality of teacher machine learning models to generate sets of radiotherapy plan parameter estimates; and reducing respective dimensions of the sets of radiotherapy plan parameter estimates or medical images, the radiotherapy plan parameters of the plurality of public training medical images being perturbed in accordance with privacy criteria; and generating a radiotherapy treatment plan based on the estimated radiotherapy plan parameters.
Techniques for adjusting radiotherapy treatment for a patient in real-time are provided. The techniques include determining a patient anatomy at a first time within a given radiotherapy treatment fraction after a radiotherapy treatment dose has been delivered by a radiotherapy device; retrieving a reference patient anatomy for the given radiotherapy treatment fraction that indicates a prescribed dose parameter to be delivered within the given radiotherapy treatment fraction; comparing the patient anatomy at the first time with the reference patient anatomy during the given radiotherapy treatment fraction; and based on the comparison of the patient anatomy at the first time with the reference patient anatomy, adjusting a parameter of the radiotherapy device to change an amount of radiotherapy treatment dose delivered at a second time, following the first time, within the given radiotherapy treatment fraction in accordance with the prescribed dose parameter to be delivered within the given radiotherapy treatment fraction.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
41.
MACHINE LEARNING BASED DOSE GUIDED REAL-TIME ADAPTIVE RADIOTHERAPY
Techniques for adjusting radiotherapy treatment for a patient in real-time are provided. The techniques include obtaining a training patient anatomy at a first time within a training radiotherapy treatment fraction after a training radiotherapy treatment dose has been delivered by a radiotherapy device; computing a deviation between the training patient anatomy at the first time and reference training patient anatomy during the training radiotherapy treatment fraction, wherein the reference training patient anatomy indicates a prescribed training dose parameter to be delivered within the training radiotherapy treatment fraction; applying the computed deviation to a machine learning model to estimate one or more intra-fraction radiotherapy treatment parameters of a function that provides a radiotherapy device parameter adjustment based on the one or more intra-fraction radiotherapy treatment parameters; and training the machine learning model to establish a relationship between the computed deviation and the one or more intra-fraction radiotherapy treatment parameters.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Techniques for adjusting radiotherapy treatment for a patient in real-time are provided. The techniques include determining a patient anatomy at a first time within a given radiotherapy treatment fraction after a radiotherapy treatment dose has been delivered by a radiotherapy device; retrieving a reference patient anatomy for the given radiotherapy treatment fraction that indicates a prescribed dose parameter to be delivered within the given radiotherapy treatment fraction; comparing the patient anatomy at the first time with the reference patient anatomy during the given radiotherapy treatment fraction; and based on the comparison of the patient anatomy at the first time with the reference patient anatomy, adjusting a parameter of the radiotherapy device to change an amount of radiotherapy treatment dose delivered at a second time, following the first time, within the given radiotherapy treatment fraction in accordance with the prescribed dose parameter to be delivered within the given radiotherapy treatment fraction.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, Magnetic Resonance
images (MR), Computed Tomography images (CT), cone beam
Computed Tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
dose and fluence maps calculation and display for
radiotherapy treatment; computer software for manipulation
of medical systems and devices; Imaging software; data
analytics software; linear accelerator management and
control software; medical database software; treatment
planning and workflow software; software for cloud based
services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form or downloadable from a computer
network or the Internet; electronic publications; remote
software applications; hardware and software for quality
assurance and calibration measurements in medical and
surgical equipment; optical receivers; optical transmitters. Medical and surgical apparatus and instruments; apparatus
and instruments for use with medical analysis for
identification, planning as well as implementing of
treatment against cancer, benign diseases or neurological
disorders using radiation; radiosurgery and radiotherapy
equipment, apparatus and instruments; image guided radiation
therapy device for use in medicine and computer software and
hardware sold as a unit therewith; test apparatus for
medical purposes; radiology apparatus for medical purposes;
collimators for medical purposes; fixation apparatus for
fixing limbs during measuring and treatment; medical and
radiographic linear accelerators; radiation beam collimation
apparatus for radiotherapy; magnetoencephalography imaging
equipment; radiographic and X-ray equipment; X-ray tubes;
X-ray imaging tubes for X-ray radiation therapy purposes;
radiation delivery devices for medical purposes; X-ray image
intensifiers for medical purposes; accelerators for charged
particles for therapeutic purposes; medical imaging
apparatus for the creation or transmission of images, video
or data relating to a medical treatment for diagnostic or
clinical use; surgery, therapy, medical treatment and
operating tables, beds and couches; special furniture for
medical use; medical tools, equipment and apparatus for
manipulating and positioning of patients; patient
restraints; imaging and treatment simulation apparatus for
treatment planning and simulation; medical imaging
equipment; X-ray radiographic and fluoroscopic imaging
systems for medical purposes; parts and fittings for all the
aforesaid goods.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, Magnetic Resonance
images (MR), Computed Tomography images (CT), cone beam
Computed Tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
dose and fluence maps calculation and display for
radiotherapy treatment; computer software for manipulation
of medical systems and devices; Imaging software; data
analytics software; linear accelerator management and
control software; medical database software; treatment
planning and workflow software; software for cloud based
services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form or downloadable from a computer
network or the Internet; electronic publications; remote
software applications; hardware and software for quality
assurance and calibration measurements in medical and
surgical equipment; optical receivers; optical transmitters. Medical and surgical apparatus and instruments; apparatus
and instruments for use with medical analysis for
identification, planning as well as implementing of
treatment against cancer, benign diseases or neurological
disorders using radiation; radiosurgery and radiotherapy
equipment, apparatus and instruments; image guided radiation
therapy device for use in medicine and computer software and
hardware sold as a unit therewith; test apparatus for
medical purposes; radiology apparatus for medical purposes;
collimators for medical purposes; fixation apparatus for
fixing limbs during measuring and treatment; medical and
radiographic linear accelerators; radiation beam collimation
apparatus for radiotherapy; magnetoencephalography imaging
equipment; radiographic and X-ray equipment; X-ray tubes;
X-ray imaging tubes for X-ray radiation therapy purposes;
radiation delivery devices for medical purposes; X-ray image
intensifiers for medical purposes; accelerators for charged
particles for therapeutic purposes; medical imaging
apparatus for the creation or transmission of images, video
or data relating to a medical treatment for diagnostic or
clinical use; surgery, therapy, medical treatment and
operating tables, beds and couches; special furniture for
medical use; medical tools, equipment and apparatus for
manipulating and positioning of patients; patient
restraints; imaging and treatment simulation apparatus for
treatment planning and simulation; medical imaging
equipment; X-ray radiographic and fluoroscopic imaging
systems for medical purposes; parts and fittings for all the
aforesaid goods.
Techniques for generating a radiotherapy treatment plan are provided. The techniques include receiving an input parameter related to a patient, the input parameter being of a given type; processing the input parameter with a machine learning technique to estimate a realizable plan parameter of a radiotherapy treatment plan, wherein the machine learning technique is trained to establish a relationship between the given type of input parameter and a set of realizable radiotherapy treatment plan parameters to achieve a target radiotherapy dose distribution; and generating the radiotherapy treatment plan based on the estimated realizable plan parameter.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
Image reconstruction can include using a statistical or machine learning, MAP estimator, or other reconstruction technique to produce a reconstructed image from acquired imaging data. A Conditional Generative Adversarial Network (CGAN) technique can be used to train a Generator, using a Discriminator, to generate posterior distribution sampled images that can be displayed or further processed such as to help provide uncertainty information about a mean reconstruction image. Such uncertainty information can be useful to help understand or even visually modify the mean reconstruction image. Similar techniques can be used in a segmentation use-case, instead of a reconstruction use case. The uncertainty information can also be useful for other post-processing techniques.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of medical images for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; computer software for handling, displaying, transmitting and transfer of patient data and information; computer software for the generation, capture, analysis and display of medical images for use in radiotherapy equipment and linear accelerators for provision of radiotherapy, including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); computer software for dose and fluence maps calculation and display for radiotherapy treatment; computer software for manipulation of medical systems and devices for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; Imaging software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; data analytics software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; linear accelerator management and control software; medical database software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; treatment planning and workflow software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software for cloud based services, data analytics and informatics for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software for remote access allowing wireless connectivity for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; optical receivers; optical transmitters. Medical and surgical apparatus for use in radio therapy; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer and benign diseases for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; test apparatus for medical purposes; radiology apparatus for medical purposes; collimators for medical purposes; fixation apparatus for fixing limbs during measuring and treatment; medical and radiographic linear accelerators; radiation beam collimation apparatus for radiotherapy; magnetoencephalography imaging equipment; radiographic and X-ray equipment; X-ray tubes; X-ray imaging tubes for X-ray radiation therapy purposes; radiation delivery devices for medical purposes; X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images; medical imaging apparatus for video or data relating to a medical treatment for diagnostic or clinical use for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; medical couches for use in radio therapy; tools, equipment and apparatus for manipulating and positioning of patients in situ for use in radio therapy; patient restraints in situ for use in radio therapy; imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging equipment for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; X-ray radiographic for medical purposes; fluoroscopic imaging systems for medical purposes for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; parts and fittings for all the aforesaid goods.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Recorded and downloadable computer software for use with medical treatment, namely, for planning and simulation of medical treatment, namely, for use in radiotherapy; recorded and downloadable computer software for handling, displaying, transmitting and transfer of patient data, information and medical images for use in radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable computer software for the generation, capture, analysis and display of medical images for use in radiotherapy equipment and linear accelerators for use in radiotherapy including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); recorded and downloadable computer software for dose and fluence maps calculation and display for radiotherapy treatment; recorded and downloadable computer software for manipulation of medical systems and devices for use in radiotherapy equipment and linear accelerators for use in radiotherapy; downloadable imaging software for use in radiotherapy equipment and linear accelerators for use in radiotherapy, namely for scanning, processing and uploading images; recorded and downloadable data analytics software for radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable linear accelerator management and control software; recorded and downloadable medical database management software for use in radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable treatment planning and workflow management software for use in radiotherapy equipment and linear accelerators for use in radiotherapy; downloadable software for cloud based services, data analytics and informatics for use with radiotherapy equipment and linear accelerators for use in radiotherapy, namely, for storing and managing electronic data, editing digital photos, sharing and uploading data; recorded and downloadable software for remote access allowing wireless connectivity for use in radiotherapy equipment and linear accelerators for use in radio therapy; recorded and downloadable software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; recorded and downloadable quality assurance software for use with radiosurgery and radiotherapy equipment, namely, for data processing, running diagnostic checks, sharing and uploading data; recorded and downloadable calibration for use in calibrating radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable software and computerized systems consisting of computer hardware and recorded software for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically and optically recorded on computer media and pre-recorded optical discs in the field of radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable electronic publications, namely, user, training and instruction manuals for the aforesaid goods, all provided in electronic form and downloadable from a computer network or the Internet; electronic publications recorded on computer media and downloadable in the nature of scientific articles on the subject of radiation therapy; recorded and downloadable remote software applications for planning, simulating, and administering radiotherapy treatments and for managing patient data, treatment delivery data, patient record archiving, and clinical charting; computer hardware and downloadable and recorded software for quality assurance and calibration measurements in medical and surgical equipment for use in radiotherapy equipment and linear accelerators for use in radiotherapy; optical receivers; electronic and optical communications instruments and components, namely, optical transmitters Medical and surgical apparatus for use in radiotherapy; medical radiation apparatus, namely, apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation for use in radiotherapy equipment and linear accelerators for use in radiotherapy; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and recorded computer software and hardware sold as a unit therewith; test apparatus for medical purposes namely, medical diagnostic apparatus for tissue-based diagnostic testing, cytology, and cell-based testing in the field of oncology; radiology apparatus for medical purposes; collimators specially adapted for medical purposes; medical fixation apparatus for fixing limbs in a specified position during measuring and treatment; medical and radiographic linear accelerators for medical use; radiation beam collimation apparatus for radiotherapy; medical imaging apparatus, namely, magnetoencephalography imaging equipment; radiographic and X-ray equipment for medical use; X-ray tubes for medical purposes; X-ray imaging tubes for X-ray radiation therapy purposes for medical purposes; medical radiation apparatus, namely, radiation delivery devices for medical purposes; medical imaging apparatus, namely, X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic cancer treatment purposes, medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; furniture especially made for medical purposes, namely, medical couches for use in radiotherapy; medical tools, equipment and apparatus, namely, radiotherapy apparatus for manipulating and positioning of patients in situ for radiotherapy; patient safety restraints in situ for radiotherapy; medical imaging and treatment simulation apparatus for treatment planning and simulation in the nature of medical diagnostic and treatment apparatus for detecting and treating cancer, not being teaching aids; medical imaging apparatus, namely, medical imaging equipment for use in radiotherapy equipment and linear accelerators for use in radiotherapy; X-ray radiographic and fluoroscopic imaging systems for medical purposes for use in radiotherapy equipment and linear accelerators for provision of radiotherapy consisting of X-ray diagnostic apparatus and medical imaging apparatus; structural and replacement parts and fittings for all the aforesaid goods
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of medical images for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; computer software for handling, displaying, transmitting and transfer of patient data and information; computer software for the generation, capture, analysis and display of medical images for use in radiotherapy equipment and linear accelerators for provision of radiotherapy including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); computer software for dose and fluence maps calculation and display for radiotherapy treatment; computer software for manipulation of medical systems and devices for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; Imaging software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; data analytics software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; linear accelerator management and control software; medical database software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; treatment planning and workflow software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software for cloud based services, data analytics and informatics for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software for remote access allowing wireless connectivity for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; optical receivers; optical transmitters. Medical and surgical apparatus for use in radiotherapy; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer and benign diseases for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; test apparatus for medical purposes; radiology apparatus for medical purposes; collimators for medical purposes; fixation apparatus for fixing limbs during measuring and treatment; medical and radiographic linear accelerators; radiation beam collimation apparatus for radiotherapy; magnetoencephalography imaging equipment; radiographic and X-ray equipment; X-ray tubes; Xray imaging tubes for X-ray radiation therapy purposes; radiation delivery devices for medical purposes; X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images; medical imaging apparatus for video or data relating to a medical treatment for diagnostic or clinical use for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; medical couches for use in radiotherapy; tools, equipment and apparatus for manipulating and positioning of patients in situ for use in radiotherapy; patient restraints in situ for use in radiotherapy; imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging equipment for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; X-ray radiographic for medical purposes; fluoroscopic imaging systems for medical purposes for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; parts and fittings for all the aforesaid goods.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Recorded and downloadable computer software for use with medical treatment, namely, for planning and simulation of medical treatment, namely, for use in radiotherapy; recorded and downloadable computer software for handling, displaying, transmitting and transfer of medical images for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; computer software for handling, displaying, transmitting and transfer of patient data and information for use in radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable computer software for the generation, capture, analysis and display of medical images for use in radiotherapy equipment and linear accelerators for use in radiotherapy, including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); recorded and downloadable computer software for dose and fluence maps calculation and display for radiotherapy treatment; recorded and downloadable computer software for manipulation of medical systems and devices for use in radiotherapy equipment and linear accelerators for use in radiotherapy; downloadable imaging software for use in radiotherapy equipment and linear accelerators for use in radiotherapy, namely, for scanning, processing and uploading images; recorded and downloadable data analytics software for radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable linear accelerator management and control software; recorded and downloadable medical database management software for use in radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable treatment planning and workflow management software for use in radiotherapy equipment and linear accelerators for use in radiotherapy; downloadable software for cloud based services, data analytics and informatics for use with radiotherapy equipment and linear accelerators for use in radiotherapy, namely, for storing and managing electronic data, editing digital photos, sharing and uploading data; recorded and downloadable software for remote access allowing wireless connectivity for use in radiotherapy equipment and linear accelerators for use in radio therapy; recorded and downloadable software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; recorded and downloadable quality assurance software for use with radiosurgery and radiotherapy equipment, namely, for data processing, running diagnostic checks, sharing and uploading data; recorded and downloadable calibration for use in calibrating radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable software and computerized systems consisting of computer hardware and recorded software for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically and optically recorded on computer media and pre-recorded optical discs in the field of radiotherapy equipment and linear accelerators for use in radiotherapy; recorded and downloadable electronic publications, namely, user, training and instruction manuals for the aforesaid goods, all provided in electronic form and downloadable from a computer network or the Internet; electronic publications recorded on computer media and downloadable in the nature of scientific articles on the subject of radiation therapy; recorded and downloadable remote software applications for planning, simulating, and administering radiotherapy treatments and for managing patient data, treatment delivery data, patient record archiving, and clinical charting; computer hardware and downloadable and recorded software for quality assurance and calibration measurements in medical and surgical equipment for use in radiotherapy equipment and linear accelerators for use in radiotherapy; optical receivers; electronic and optical communications instruments and components, namely, optical transmitters Medical and surgical apparatus for use in radiotherapy; medical radiation apparatus, namely, apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer and benign diseases for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against neurological disorders using radiation for use in radiotherapy equipment and linear accelerators for use in radiotherapy; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and recorded computer software and hardware sold as a unit therewith; test apparatus for medical purposes, namely, medical diagnostic apparatus for tissue-based diagnostic testing, cytology, and cell-based testing in the field of oncology; radiology apparatus for medical purposes; collimators specially adapted for medical purposes; medical fixation apparatus for fixing limbs in a specified position during measuring and treatment; medical and radiographic linear accelerators for medical use; radiation beam collimation apparatus for radiotherapy; medical imaging apparatus, namely, magnetoencephalography imaging equipment; radiographic and X-ray equipment for medical use; X-ray tubes for medical purposes; X-ray imaging tubes for X-ray radiation therapy purposes for medical purposes; medical radiation apparatus, namely, radiation delivery devices for medical purposes; medical imaging apparatus, namely, X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic cancer treatment purposes, medical imaging apparatus for the creation or transmission of images; medical imaging apparatus for video or data relating to a medical treatment for diagnostic or clinical use for use in radiotherapy equipment and linear accelerators for provision of radiotherapy; furniture especially made for medical purposes, namely, medical couches for use in radiotherapy; medical tools, equipment and apparatus, namely, radiotherapy apparatus for manipulating and positioning of patients in situ for radiotherapy; patient safety restraints in situ for radiotherapy; medical imaging and treatment simulation apparatus for treatment planning and simulation in the nature of medical diagnostic and treatment apparatus for detecting and treating cancer, not being teaching aids; medical imaging apparatus, namely, medical imaging equipment for use in radiotherapy equipment and linear accelerators for use in radiotherapy; X-ray radiographic for medical purposes; fluoroscopic imaging systems for medical purposes for use in radiotherapy equipment and linear accelerators for provision of radiotherapy consisting of X-ray diagnostic apparatus and medical imaging apparatus; structural and replacement parts and fittings for all the aforesaid goods
Systems and methods for calculating radiotherapy dose distribution are provided. The systems and methods include operations for receiving data representing at least one of particle trajectories or a dose deposition pattern in a simulated delivery of a radiotherapy plan; applying a dose calculation process to the received data to generate a first radiotherapy dose distribution having a first level of detail; and processing the first radiotherapy dose distribution using a trained machine learning technique to generate a second radiotherapy dose distribution having a second level of detail that enhances the first level of detail.
Embodiments of the present disclosure are directed to treatment planning systems for a radiotherapy apparatus. In one implementation, a treatment planning system may include a computational processor configured to apply a set of instructions to an input data set. The input data set may include a three-dimensional dose distribution for delivery by the radiotherapy apparatus to a volume to be irradiated, a three-dimensional volume image characterizing tissue types within the volume to be irradiated, and a set of apparatus parameters which characterize the radiotherapy apparatus. The set of instructions may include a computational process configured to output a treatment plan for delivery of the dose distribution by the radiotherapy apparatus, by optimising a function representing a time-dependent response of the tissue types to an applied radiation.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, Magnetic Resonance
images (MR), Computed Tomography images (CT), cone beam
Computed Tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
dose and fluence maps calculation and display for
radiotherapy treatment; computer software for manipulation
of medical systems and devices; Imaging software; data
analytics software; linear accelerator management and
control software; medical database software; treatment
planning and workflow software; software for cloud based
services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form or downloadable from a computer
network or the Internet; electronic publications; remote
software applications; hardware and software for quality
assurance and calibration measurements in medical and
surgical equipment; optical receivers; optical transmitters. Medical and surgical apparatus and instruments; apparatus
and instruments for use with medical analysis for
identification, planning as well as implementing of
treatment against cancer, benign diseases or neurological
disorders using radiation; radiosurgery and radiotherapy
equipment, apparatus and instruments; image guided radiation
therapy device for use in medicine and computer software and
hardware sold as a unit therewith; test apparatus for
medical purposes; radiology apparatus for medical purposes;
collimators for medical purposes; fixation apparatus for
fixing limbs during measuring and treatment; medical and
radiographic linear accelerators; radiation beam collimation
apparatus for radiotherapy; magnetoencephalography imaging
equipment; radiographic and X-ray equipment; X-ray tubes;
X-ray imaging tubes for X-ray radiation therapy purposes;
radiation delivery devices for medical purposes; X-ray image
intensifiers for medical purposes; accelerators for charged
particles for therapeutic purposes; medical imaging
apparatus for the creation or transmission of images, video
or data relating to a medical treatment for diagnostic or
clinical use; surgery, therapy, medical treatment and
operating tables, beds and couches; special furniture for
medical use; medical tools, equipment and apparatus for
manipulating and positioning of patients; patient
restraints; imaging and treatment simulation apparatus for
treatment planning and simulation; medical imaging
equipment; X-ray radiographic and fluoroscopic imaging
systems for medical purposes; parts and fittings for all the
aforesaid goods.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Recorded and downloadable computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); recorded and downloadable computer software for dose and fluence maps calculation and display for radiotherapy treatment; recorded and downloadable software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; electronic database in the field of radiation therapy recorded on computer media; electronic publications recorded on computer media or downloadable in the nature of user, training and instruction manuals relating to radiation therapy medical equipment and recorded and downloadable software used in connection therewith; electronic publications recorded on computer media or downloadable in the nature of scientific articles on the subject of radiation therapy; all of the aforesaid goods being for use in radiation therapy Medical apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and recorded computer software and hardware for operation thereof sold as a unit therewith; radiology apparatus for medical purposes; collimators for medical purposes in providing radiation therapy; medical fixation apparatus for fixing limbs in a specified position during measuring and treatment; medical and radiographic linear accelerators for medical use; radiation beam collimation apparatus for radiotherapy; magnetoencephalography imaging equipment for medical use; radiographic and X-ray equipment for medical use; X-ray tubes for medical purposes; X-ray imaging tubes for X-ray radiation therapy purposes; radiation delivery devices for medical purposes; X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic cancer treatment purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; furniture specially made for medical purposes, namely, surgery, therapy, medical treatment and operating tables, beds and couches, excluding furniture for transporting or incubating patients; medical tools, equipment and apparatus for manipulating and positioning of patients, namely, instruments that hold patients in a specified position to allow for precise delivery of oncology treatments; patient safety restraints; medical imaging apparatus for treatment planning; X-ray radiographic and fluoroscopic imaging systems for medical purposes; structural parts and fittings for all the aforesaid goods; all of the aforesaid goods being for use in radiation therapy
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, magnetic resonance
images (MR), computed tomography images (CT), cone beam
computed tomography (CBCT) images, ultrasound images,
positron emission tomography images, single-photon emission
computed tomography images (SPECT); computer software for
dose and fluence maps calculation and display for
radiotherapy treatment; computer software for manipulation
of medical systems and devices; imaging software; data
analytics software; linear accelerator management and
control software; medical database software; treatment
planning and workflow software; software for cloud based
services, data analytics and informatics; software for
remote access allowing wireless connectivity; software for
measuring and analyzing radiation dose delivery in
radiosurgery and radiotherapy equipment; quality assurance
software; calibration software; software and computerized
systems for management of clinical information and patient
data, treatment delivery, patient record archiving and
clinical charting; data and databases all recorded
electronically, magnetically or optically; user, training
and instruction manuals for the aforesaid goods, all
provided in electronic form or downloadable from a computer
network or the internet; electronic publications; remote
software applications; hardware and software for quality
assurance and calibration measurements in medical and
surgical equipment; optical receivers; optical transmitters. Medical and surgical apparatus and instruments; apparatus
and instruments for use with medical analysis for
identification, planning as well as implementing of
treatment against cancer, benign diseases or neurological
disorders using radiation; radiosurgery and radiotherapy
equipment, apparatus and instruments; image guided radiation
therapy device for use in medicine and computer software and
hardware sold as a unit therewith; test apparatus for
medical purposes; radiology apparatus for medical purposes;
collimators for medical purposes; fixation apparatus for
fixing limbs during measuring and treatment; medical and
radiographic linear accelerators; radiation beam collimation
apparatus for radiotherapy; magnetoencephalography imaging
equipment; radiographic and X-ray equipment; X-ray tubes;
X-ray imaging tubes for X-ray radiation therapy purposes;
radiation delivery devices for medical purposes; X-ray image
intensifiers for medical purposes; accelerators for charged
particles for therapeutic purposes; medical imaging
apparatus for the creation or transmission of images, video
or data relating to a medical treatment for diagnostic or
clinical use; surgery, therapy, medical treatment and
operating tables, beds and couches; special furniture for
medical use; medical tools, equipment and apparatus for
manipulating and positioning of patients; patient
restraints; imaging and treatment simulation apparatus for
treatment planning and simulation; medical imaging
equipment; X-ray radiographic and fluoroscopic imaging
systems for medical purposes; parts and fittings for all the
aforesaid goods.
56.
SYSTEM AND METHOD FOR DETERMINING ARC DOSE FOR ARC THERAPY
Systems and methods are provided for radiation delivery. An exemplary method includes receiving an image depicting anatomical data of a target region of patient tissue and determining an initial prescribed dose of radiotherapeutic radiation to be delivered to the target region. The method also includes discretizing the arc for VMAT into a plurality of arc segments and performing an iteration process for determining an arc dose according to radiation delivered in the arc segments. The method further includes determining whether a condition for terminating the iteration process is met and terminating the iteration process based on a result of the determination that the condition for terminating the iteration process is met.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Recorded and downloadable computer software for the generation, capture, analysis and display of medical images including X-rays, magnetic resonance images (MR), computed tomography images (CT), cone beam computed tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography images (SPECT); recorded and downloadable computer software for dose and fluence maps calculation and display for radiotherapy treatment; recorded and downloadable software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; electronic database in the field of radiation therapy recorded on computer media; Electronic publications recorded on computer media or downloadable in the nature of user, training and instruction manuals relating to radiation therapy medical equipment and software used in connection therewith; electronic publications recorded on computer media or downloadable in the nature of scientific articles on the subject of radiation therapy; all of the aforesaid goods being for use in radiation therapy Medical apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine and recorded computer software and hardware for operation thereof sold as a unit therewith; radiology apparatus for medical purposes; collimators for medical purposes in providing radiation therapy; medical fixation apparatus for fixing limbs in a specified position during measuring and treatment; medical and radiographic linear accelerators for medical use; radiation beam collimation apparatus for radiotherapy; magnetoencephalography imaging equipment for medical use; radiographic and X-ray equipment for medical use; X-ray tubes for medical purposes; X-ray imaging tubes for X-ray radiation therapy purposes; radiation delivery devices for medical purposes; X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic cancer treatment purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; furniture specially made for medical purposes, namely, surgery, therapy, medical treatment and operating tables, beds and couches, excluding furniture for transporting or incubating patients; medical tools, equipment and apparatus for manipulating and positioning of patients, namely, instruments that hold patients in a specified position to allow for precise delivery of oncology treatments; patient safety restraints; medical imaging apparatus for treatment planning; X-ray radiographic and fluoroscopic imaging systems for medical purposes; parts and fittings for all the aforesaid goods; all of the aforesaid goods being for use in radiation therapy
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for dose and fluence maps calculation and display for radiotherapy treatment; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; all of the aforesaid goods being for use in radiation therapy. Apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; radiology apparatus for medical purposes; collimators for medical purposes; fixation apparatus for fixing limbs during measuring and treatment; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; radiographic and x-ray equipment; X-ray tubes; X-ray imaging tubes for radiation technology; Radiation delivery devices; x-ray image intensifiers; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; Patient positioning systems, tools and manipulating apparatus and fixings; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels; parts and fittings for all the aforesaid goods; all of the aforesaid goods being for use in radiation therapy.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for dose and fluence maps calculation and display for radiotherapy treatment; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; all of the aforesaid goods being for use in radiation therapy. Apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; test apparatus for medical purposes; radiology apparatus for medical purposes; collimators for medical purposes; fixation apparatus for fixing limbs during measuring and treatment; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; radiographic and x-ray equipment; X-ray tubes; X-ray imaging tubes for radiation technology; Radiation delivery devices; x-ray image intensifiers; accelerators for charged particles for therapeutic purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; Patient positioning systems, tools and manipulating apparatus and fixings; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels; parts and fittings for all the aforesaid goods; all of the aforesaid goods being for use in radiation therapy.
60.
MODALITY-AGNOSTIC METHOD FOR MEDICAL IMAGE REPRESENTATION
Techniques for the operation and use of a model that learns the general representation of multimodal images are disclosed. In various examples, methods from representation learning are used to find a common basis for representation of medical images. These include aspects of encoding, fusion, and downstream tasks, with use of the general representation and model. In an example, a method for generating a modality-agnostic model includes receiving imaging data, encoding the imaging data by mapping data to a latent representation, fusing the encoded data to conserve latent variables corresponding to the latent representation, and training a model using the latent representation. In an example, a method for processing imaging data using a trained modality-agnostic model includes receiving imaging data, encoding the data to the defined encoding, processing the encoded data with a trained model, and performing imaging processing operations based on output of the trained model.
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
61.
Modality-agnostic method for medical image representation
Techniques for the operation and use of a model that learns the general representation of multimodal images is disclosed. In various examples, methods from representation learning are used to find a common basis for representation of medical images. These include aspects of encoding, fusion, and downstream tasks, with use of the general representation and model. In an example, a method for generating a modality-agnostic model includes receiving imaging data, encoding the imaging data by mapping data to a latent representation, fusing the encoded data to conserve latent variables corresponding to the latent representation, and training a model using the latent representation. In an example, a method for processing imaging data using a trained modality-agnostic model includes receiving imaging data, encoding the data to the defined encoding, processing the encoded data with a trained model, and performing imaging processing operations based on output of the trained model.
G06N 3/04 - Architecture, e.g. interconnection topology
G06T 7/174 - Segmentation; Edge detection involving the use of two or more images
H04N 19/176 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using adaptive coding characterised by the coding unit, i.e. the structural portion or semantic portion of the video signal being the object or the subject of the adaptive coding the unit being an image region, e.g. an object the region being a block, e.g. a macroblock
Image reconstruction can include using a statistical or machine learning, MAP estimator, or other reconstruction technique to produce a reconstructed image from acquired imaging data. A Conditional Generative Adversarial Network (CGAN) technique can be used to train a Generator, using a Discriminator, to generate posterior distribution sampled images that can be displayed or further processed such as to help provide uncertainty information about a mean reconstruction image. Such uncertainty information can be useful to help understand or even visually modify the mean reconstruction image. Similar techniques can be used in a segmentation use-case, instead of a reconstruction use case. The uncertainty information can also be useful for other post-processing techniques.
Image reconstruction can include using a statistical or machine learning, MAP estimator, or other reconstruction technique to produce a reconstructed image from acquired imaging data. A Conditional Generative Adversarial Network (CGAN) technique can be used to train a Generator, using a Discriminator, to generate posterior distribution sampled images that can be displayed or further processed such as to help provide uncertainty information about a mean reconstruction image. Such uncertainty information can be useful to help understand or even visually modify the mean reconstruction image. Similar techniques can be used in a segmentation use-case, instead of a reconstruction use case. The uncertainty information can also be useful for other post-processing techniques.
Methods, devices, and computer-readable storage media for identifying an object in an image, the method including using a first neural network to identify an approximate position of an object of interest in an image and identifying based on the approximate position, a section of the image that includes the object of interest. A plurality of sub-images corresponding to the identified section of the image are applied to a plurality of second neural networks to determine a plurality of second positions of the object of interest. The plurality of second positions are statistically analyzed to determine an output position of the object of interest.
A lifting apparatus for a facility combining magnetic resonance imaging apparatus and radiotherapy apparatus inside a purpose-built structure having a fixed wall, the lifting apparatus comprising a wall-mounted articulating jib crane which is selectively moveable between a stowed state and a free state in which it is operable as a crane, in which substantially all of the load-bearing parts of the crane are made of non-ferromagnetic metal, and in which guides are mounted to the wall to receive and to releasably hold the crane in a fixed position relative to the wall when the crane is in the stowed state.
B66C 23/68 - Jibs foldable or otherwise adjustable in configuration
B66C 23/20 - Cranes comprising essentially a beam, boom or triangular structure acting as a cantilever and mounted for translatory or swinging movements in vertical or horizontal planes or a combination of such movements, e.g. jib cranes, derricks or tower cranes specially adapted for use in particular locations or for particular purposes with supporting couples provided by walls of buildings or like structures
A radiotherapy apparatus includes a rotatable drum on which is mounted a gantry arm carrying a radiation source. The arm extending from the drum to a location of the radiation source is offset from the axis of rotation of the drum and oriented towards the axis. The radiotherapy apparatus further includes a mechanism configured to apply a tilt to the arm at one or more rotational orientations of the drum. The rotatable drum is supported on wheels beneath the drum, and the mechanism is an eccentric mechanism within the wheels and is configured to apply the tilt to the arm via the wheels.
Much of the image processing that is applied to medical images is a form of "inverse problem". This is a class of mathematical problems in which a "forward" model by which a signal is converted into dataset is known, to at least some degree, but where the aim is to reconstruct the signal given the resulting dataset. Thus, an inverse problem is essentially seeking to discover x given knowledge of A(x)+ noise by finding an appropriate reconstruction operator A† such that A†(A(x)+ noise) ≈ x, thereby enabling us to obtain x (or a close approximation) given knowledge of an output dataset consisting of A(x)+noise. Generally, several such processes (or their equivalents) are applied to the image dataset. If the first process (for example, noise reduction) is expressed via a first reconstruction operator A1† characterised by a parameter set Θ1 and the second process (for example, segmentation) is expressed via a second reconstruction operator A2† characterised by a parameter set Θ2, then the result of the two steps applied consecutively is A2†(A1†(y)). This can be expressed as an overall reconstruction operator P+, characterised by a parameter set Φ. If we then allow a machine learning process to optimise P+, then the steps previously carried out separately can be combined into a single optimisation. This yields advantages in terms of computational load and in the accuracy of the end result.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
68.
System and method for automatic treatment planning
The present disclosure relates to systems, methods, and computer-readable storage media for radiotherapy. Embodiments of the present disclosure may receive a plurality of training data and determine one or more predictive models based on the training data. The one or more predictive models may be determined based on at least one of a conditional probability density associated with a selected output characteristic given one or more selected input variables or a joint probability density. Embodiments of the present disclosure may also receive patient specific testing data. In addition, embodiments of the present disclosure may predict a probability density associated with a characteristic output based on the one or more predictive models and the patient specific testing data. Moreover, embodiments of the present disclosure may generate a new treatment plan based on the prediction and may use the new treatment plan to validate a previous treatment plan.
The disclosed systems and methods for Image-Guided Radiation Therapy (IGRT), utilises an iterative approach which adjusts a treatment plan based on inter- or intra-fraction images to improve the accuracy of the radiation delivered during the overall treatment. The prescribed dose of radiotherapeutic radiation is mapped onto the patient's anatomy using an image acquired of the region, which is to be the target for radiotherapeutic radiation. Following beam-angle-optimisation, fluence optimisation and segmentation, the efficiency of delivery of each segment is determined using an objective function, and the segments ranked according to their efficiency. The plan proceeds with the choice of the most efficient segment (or segments) to be delivered first. When this radiation has been delivered, having been tracked to establish its distribution, this delivered distribution can be subtracted from the original prescribed dose and the process repeated so that the delivered radiation gradually converges on the original prescribed dose.
The present disclosure provides systems, methods, and computer- readable storage media for detecting an anatomical region of interest for radiotherapy planning. Embodiments of the present disclosure may identify (810) a plurality of objects in a medical image and select (820) a subset of the objects by applying a morphology filter (516) to the plurality of objects. The morphology filter may determine a morphological feature associated with each of the plurality of objects and exclude at least one object from the subset when the morphological feature of the at least one object exceeds a predetermined threshold. Embodiments of the present disclosure may also classify (830) the objects in the subset into one of a predetermined set of shapes and detect (840) the anatomical region of interest based on the classified objects in the subset.
A patient support device for positioning the patient comprising a support frame (1) and a chair (2) connected to each other, wherein the chair (2) comprises a seat portion (3) and a back portion (4) connected to each other. The back portion (4) is extending upward from the seat portion (3). The back portion (4) further comprises two opposite ends, a first end (5) and a second end (6), and the back portion (4) is connected at the second end (6) to the seat portion (3). The first end (5) of the back portion (4) determines horizontal axis A. The first end (5) of the back portion (4) is pivotally connected to the frame (1) by a rotating mechanism (7) so that the chair (2) is arranged to rotate around axis A.
The present disclosure provides systems, methods, and computer-readable storage media for detecting an anatomical region of interest for radiotherapy planning. Embodiments of the present disclosure may identify a plurality of objects in a medical image and select a subset of the objects by applying a morphology filter to the plurality of objects. The morphology filter may determine a morphological feature associated with each of the plurality of objects and exclude at least one object from the subset when the morphological feature of the at least one object exceeds a predetermined threshold. Embodiments of the present disclosure may also classify the objects in the subset into one of a predetermined set of shapes and detect the anatomical region of interest based on the classified objects in the subset.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as
with planning or simulation of medical treatment; computer
software for handling, displaying, transmitting and transfer
of patient data, information and medical images; computer
software for the generation, capture, analysis and display
of medical images including X-rays, Magnetic Resonance (MR)
images; Computed Tomography (CT) images, cone beam computed
tomography (CBCT) images, ultrasound images, positron
emission tomography images, single-photon emission computed
tomography (SPECT) images; computer software for dose and
fluence maps calculation and display for radiotherapy
treatment; computer software for manipulation of medical
systems and devices; imaging software; data analytics
software; linear accelerator management and control
software; MRI management and control software and analytics
software; medical database software; treatment planning and
workflow software; software for cloud based services, data
analytics and informatics; software for remote access
allowing wireless connectivity; software for measuring and
analyzing radiation dose delivery in radiosurgery and
radiotherapy equipment; quality assurance software;
calibration software; software and computerized systems for
management of clinical information and patient data,
treatment delivery, patient record archiving and clinical
charting; data and databases all recorded electronically,
magnetically or optically; user, training and instruction
manuals for the aforesaid goods, all provided in electronic
form or downloadable from a computer network or the
Internet; electronic publications; remote software
applications; hardware and software for quality assurance
and calibration measurements in medical and surgical
equipment; computer software and hardware for use with image
guided radiation therapy device for use in medicine. Medical and surgical apparatus and instruments; apparatus
and instruments for use with medical analysis for
identification, planning as well as implementing of
treatment against cancer, benign diseases or neurological
disorders using radiation; radiosurgery and radiotherapy
equipment, apparatus and instruments; image guided radiation
therapy device for use in medicine; MRI diagnostic
apparatus; instruments and image guidance systems for
stereotactic surgery; stereotactic radio surgery equipment;
fixtures and restraints for use in stereotactic surgery;
medical equipment and instruments for non-invasive
measurement of brain activity; test apparatus for medical
purposes; radiology apparatus for medical purposes;
apparatus for physiotherapy; collimators for medical
purposes; fixation apparatus for fixing limbs during
measuring and treatment; brachytherapy treatment delivery
systems, after-loaders, applicators and seed delivery
apparatus and fittings; magnetic resonance imaging equipment
and apparatus; medical and radiographic linear accelerators;
radiation beam collimation apparatus for radiotherapy;
magnetoencephalography imaging equipment; radiographic and
X-ray equipment; X-ray tubes; X-ray imaging tubes for
radiation technology; radiation delivery devices; X-ray
image intensifiers; accelerators for charged particles for
therapeutic purposes; ultrasonic scanners; medical imaging
apparatus for the creation or transmission of images, video
or data relating to a medical treatment for diagnostic or
clinical use; surgery, therapy, medical treatment and
operating tables, beds and couches; special furniture for
medical use; patient positioning systems, tools and
manipulating apparatus and fixings; patient restraints;
imaging and treatment simulation apparatus for treatment
planning and simulation; medical imaging equipment; X-ray
radiographic and fluoroscopic imaging systems, receivers and
transmitter panels; parts and fittings for all the aforesaid
goods. Medical education and user training; vocational guidance
(non-business) in the field of medical, therapeutic,
radiosurgical and radiotherapy techniques, appliances,
apparatus and equipment; education and training on the use
of image guided radiotherapy and image modulated radiation
therapy, oncology, oncology information systems,
stereotactic systems, brachytherapy equipment and solutions,
software and planning tools; education and training on
medical imaging techniques, apparatus and analysis;
arranging and conducting of conferences, congresses and
seminars relating to the design, use, test of medical and
surgical apparatus and software for the medical treatment of
cancer; education and training services for radiotherapy
apparatus use, dosimetry planning and dose delivery in
radiotherapy equipment. Design and development of computer hardware and software;
computer programming; updating of computer software; remote
software and data hosting services; cloud computing;
electronic data storage and off site data back-up; design
and development of medical equipment; installation,
maintenance and repair of software for computer systems;
computer software technical support services; consultation
services relating to computer software; medical software
planning and installation services; treatment room design
and planning services for medical and radiotherapy delivery
systems; software as a service for use in medical treatment
as well as with planning or simulation of medical treatment;
software as a service for handling, displaying and transfer
of patient data, information and images; software as service
for collecting analyzing and displaying medical images;
software as a service for medical analytics and infomatics.
A collimator for a radiotherapy apparatus, comprising a block of isolation-attenuating material having a front face forming the leading edge of tie block and at least one main rear face defining the trailing edge of the block, in which the or each rear face is substantially planar in the direction of the depth of the block and non-parallel to the front face. The collimator may form part of a radiotherapy apparatus, and methods of operation of such apparatus are described.
G21K 1/04 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators using variable diaphragms, shutters, choppers
A radiotherapy apparatus includes a fixed support and a gantry including a chassis part and a source part, the chassis part being rotatably attached to the fixed support to allow rotation thereof about a generally horizontal axis, and the source part being connected to the chassis part via a rotatable connection allowing the source part to rotate relative to the chassis part around a transverse axis. The source part includes a source of therapeutic radiation directed towards the intersection of the transverse axis and the horizontal axis. The chassis part and the source part together define an annular ring that encircles the horizontal axis. In this way, the radiotherapy apparatus can provide the full usual range of treatments, but can also adapt itself to adopt a non-coplanar geometry when required, for example to treat difficult locations in the head and neck.
A fluorescing marker is used in order to mark (for example) a leaf of a multi-leaf collimator and/or the reference points within the field of view. The markers are illuminated with light tuned to cause the markers to fluoresce at a wavelength different to that of the illuminating light. The fluorescence is then detected by a camera. This method allows the image to be captured by the camera with increased contrast. Accordingly, the present invention provides a multi-leaf collimator for a radiotherapeutic apparatus, comprising at least one leaf having a fluorescent marker. The fluorescent marker will usually emit light of a wavelength longer than the incident light, allowing suitable filters to be provided in order to distinguish the light emitted by the markers. A suitable material for use in the fluorescent markers is ruby. The present invention also provides a radiotherapeutic apparatus comprising a multi-leaf collimator as defined above, and a camera arranged to view the fluorescent markers. A source of illumination for the fluorescent markers is ideally monochromatic, or nearly so. The camera can have a filter arranged to substantially prevent light of the wavelength emitted by the source of illumination from entering the camera, thereby improving the contrast of the image. The radiotherapeutic apparatus can also comprise a source of illumination that is optically co-located with a radiation source, to allow the radiation field that will be emitted to be checked visually by an operator. The co-located source is preferably substantially monochromatic, emitting substantially no light at the wavelength of the fluorescent markers. A filter can then be placed over an output of the radiotherapeutic apparatus, for blocking light of the wavelength of the fluorescent markers and thereby enhancing the contrast of the image that is taken of the fluorescent markers.
G21K 1/04 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators using variable diaphragms, shutters, choppers
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for the management, tracking and assessment of dosages, and oncology and radiation treatments for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance (MR) images, Computed Tomography (CT) images, cone beam computed tomography (CBCT) images, ultrasound images, positron emission tomography images, single-photon emission computed tomography (SPECT) images; computer software for dose and fluence maps calculation and display for radiotherapy treatment; computer software for manipulation of medical systems and devices; imaging software for tracking results of radiation therapy on soft tissue; data analytics software; linear accelerator management and control software; MRI management and control software and MRI analytics software; medical database software; treatment planning and workflow software; downloadable software for cloud based services, data analytics and informatics, namely, software for analysis of patient treatments, development of personalized treatment plans, and analysis of clinical trial information; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software, namely, software for data collection and analytics; calibration software for radiotherapy, radiosurgery, MR/RT, stereostactic and brachytherapy instruments; software and integrated computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases in the field of medical informatics recorded electronically, magnetically or optically on computer media; user, training and instruction manuals for the aforesaid goods, all provided in electronic form recorded on computer media or downloadable from a computer network or the Internet; electronic publications, namely, newsletters and course materials recorded on computer media featuring information on oncology treatments and the use of radiotherapy, radiosurgery, MR/RT, stereostatic and brachytherapy instruments; remote software applications for managing oncology treatment programs; Computer hardware and software for quality assurance and calibration measurements in medical and surgical equipment; computer software and hardware for use with image guided radiation therapy device for use in medicine Medical and surgical apparatus and instruments, namely, radiotherapy, radiosurgery, MR/RT, stereostatic and brachytherapy apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; image guided radiation therapy device for use in medicine; MRI diagnostic apparatus; instruments and image guidance systems for stereotactic surgery; stereotactic radio surgery equipment; fixtures and restraints for use in stereotactic surgery; medical equipment and instruments for non-invasive measurement of brain activity; diagnostic test apparatus for medical purposes for testing effectiveness of cancer treatments; radiology apparatus for medical purposes; medical apparatus for physiotherapy; collimators for medical purposes; orthopedic fixation apparatus for fixing limbs during measuring and treatment; brachytherapy treatment delivery systems, after-loaders, applicators and radioactive seed delivery apparatus and fittings; magnetic resonance imaging equipment and apparatus for medical purposes; medical and radiographic linear accelerators; radiation beam collimation apparatus for radiotherapy; magnetoencephalography imaging equipment for medical purposes; radiographic and X-ray equipment for medical purposes; X-ray tubes for medical purposes; X-ray imaging tubes for radiation technology for medical purposes; radiation drug delivery devices; X-ray image intensifiers for medical purposes; accelerators for charged particles for therapeutic purposes; ultrasonic scanners for medical purposes; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; patient positioning systems, tools and manipulating apparatus and fixings, namely, instruments that hold patients in a specified position to allow for precise delivery of oncology treatments; patient safety restraints; imaging and treatment simulation apparatus for medical treatment planning and simulation; medical imaging equipment; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels for medical purposes; parts and fittings for all the aforesaid goods Medical education courses and end-user training on medical device products; non-business vocational guidance in the field of medical, therapeutic, radiosurgical and radiotherapy techniques, appliances, apparatus and equipment; education courses and training on the use of image guided radiotherapy and image modulated radiation therapy, oncology, oncology information systems, stereotactic systems, brachytherapy equipment and solutions, software and planning tools; education courses and training on medical imaging techniques, apparatus and analysis; arranging and conducting of educational conferences, congresses and seminars relating to the design, use, test of medical and surgical apparatus and software for the medical treatment of cancer; education courses and training services for radiotherapy apparatus use, dosimetry planning and dose delivery in radiotherapy equipment Design and development of computer hardware and software; computer programming; updating of computer software; remote software and data hosting services, namely, application service provider hosting software and data of others in the fields of oncology research and treatements; cloud computing featuring software for use in providing, managing and monitoring oncology treatments and clinical trials; electronic data storage and off site data back-up; design and development of medical equipment; installation, maintenance and repair of software for computer systems; computer software technical support services, namely, troubleshooting of computer software problems; consultation services relating to computer software; medical software planning in the nature of design and development and installation services; interior design services, namely, treatment room design and planning services for medical and radiotherapy delivery systems; software as a service featuring software for for the management, tracking and assessment of dosages, and oncology and radiation treatments for use in medical treatment as well as with planning or simulation of medical treatment; software as a service featuring software for handling, displaying and transfer of patient data, information and images; software as service featuring software for collecting analyzing and displaying medical images; software as a service featuring software for software for analysis of patient treatments, development of personalized treatment plans, and analysis of clinical trial information for medical analytics and informatics
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR); Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for dose and fluence maps calculation and display for radiotherapy treatment: computer software for manipulation of medical systems and devices; Imaging software; data analytics software; Linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; Software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; Software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment. Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; MRI diagnostic apparatus; instruments and image guidance systems for stereotactic surgery; Stereotactic radio surgery equipment; fixtures and restraints for use in stereotactic surgery; medical equipment and instruments for non-invasive measurement of brain activity; test apparatus for medical purposes; radiology apparatus for medical purposes; apparatus for physiotherapy; collimators for medical purposes; and fixation apparatus for fixing limbs during measuring and treatment; Brachytherapy treatment delivery systems, after-loaders, applicators and seed delivery apparatus and fittings; Magnetic Resonance Imaging equipment and apparatus; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; radiographic and x-ray equipment; X-ray tubes; X-ray imaging tubes for radiation technology; Radiation delivery devices; x-ray image intensifiers; accelerators for charged particles for therapeutic purposes; Ultrasonic scanners; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; Patient positioning systems, tools and manipulating apparatus and fixings; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging equipment; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels; parts and fittings for all the aforesaid goods. Medical education and user training; vocational guidance (non-business) in the field of medical, therapeutic, radiosurgical and radiotherapy techniques, appliances, apparatus and equipment; education and training on the use of image guided radiotherapy and image modulated radiation therapy, oncology, oncology information systems, stereotactic systems, brachytherapy equipment and solutions, software and planning tools; education and training on medical imaging techniques, apparatus and analysis; arranging and conducting of conferences, congresses and seminars relating to the design, use, test of medical and surgical apparatus and software for the medical treatment of cancer; education and training services for radiotherapy apparatus use, dosimetry planning and dose delivery in radiotherapy equipment. Design and development of computer hardware and software; computer programming; updating of computer software; remote software and data hosting services; cloud computing; electronic data storage and off site data back-up; design and development of medical equipment; Installation, maintenance and repair of software for computer systems; Computer software technical support services; Consultation services relating to computer software; Medical software planning and installation services; treatment room design and planning services for medical and radiotherapy delivery systems; Software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; Software as service for collecting analyzing and displaying medical images; Software as a service for medical analytics and infomatics.
Radiotherapy apparatus comprises a source of radiation mounted on a chassis, the chassis being rotatable about a rotation axis and the source being adapted to emit a beam of radiation along a beam axis that intersects with the rotation axis; a patient support, moveable along a translation axis; a set of magnetic coils located on either side of the beam, for establishing a magnetic field at the point of intersection, spaced from that point along a first direction; the translation axis, the rotation axis, and the first direction being substantially parallel; and further comprising a multi-leaf collimator fixed in its orientation with respect to the source of radiation, the multi-leaf collimator comprising a plurality of elongate leaves disposed with their longitudinal directions substantially aligned with the first direction and movable in that direction between a withdrawn position in which the leaf lies outside the beam.
The present disclosure relates to systems, methods, and computer-readable storage devices for radiotherapy treatment planning. For example, a method may generate a treatment plan for a patient. The method may receive training data reflecting radiotherapy treatment data. The training data may include a feature vector and a target vector. The method may further determine a training model based on the feature vector and the target vector. The method may further receive testing data associated with the patient. The testing data may include a descriptive feature vector. The method may further determine a therapy model based on the descriptive feature vector and the training model. The therapy model may be used to generate the treatment plan.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
81.
Systems and methods for optimizing treatment planning
The present disclosure relates to systems, methods, and computer-readable storage devices for radiotherapy treatment planning. For example, a method may generate a treatment plan for a patient. The method may receive training data reflecting radiotherapy treatment data. The training data may include a feature vector and a target vector. The method may further determine a training model based on the feature vector and the target vector. The method may further receive testing data associated with the patient. The testing data may include a descriptive feature vector. The method may further determine a therapy model based on the descriptive feature vector and the training model. The therapy model may be used to generate the treatment plan.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 70/20 - ICT specially adapted for the handling or processing of medical references relating to practices or guidelines
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
Existing radiotherapy treatment planning protocols treat a cancer as a fixed entity within a "target volume". Efforts have been directed towards faster or more accurate planning processes and more accurate or reliable delivery methods. We propose a treatment planning system for a radiotherapy apparatus comprising a computational processor applying a set of instructions to an input data set, the input data set comprising a three-dimensional dose distribution which is to be achieved by the radiotherapy apparatus within a volume to be irradiated, a three-dimensional volume image characterising the tissue types within the volume to be irradiated, and a set of apparatus parameters which characterise the radiotherapy apparatus, with the set of instructions including a computational process arranged to output a treatment plan apt to deliver the three-dimensional dose distribution when implemented by the radiotherapy apparatus, by optimising a function that includes at least one term representing a time-dependent response of the tissue types to an applied radiation. The set of instructions can then include a fractional distribution step arranged to assign fractional parts of the dose distribution to successive treatment fractions, taking into account time- and dose-dependent characteristics of the tissue types within the volume image, and the iterative computational process can then be arranged, for each non-identical fraction, to take into account the fractional part of the dose distribution and the set of apparatus parameters, to derive a set of treatment instructions apt to deliver the fractional part when carried out by the radiotherapy apparatus. The three-dimensional volume image will ideally characterise the tissue types according to at least their local chemical composition, to assist in modelling the dose response. The optimisation function can include terms representing time-dependent responses such as a cell repair model and a tumour diffusion model.
Embodiments disclose a radiotherapy apparatus comprising a source of radiation configured to emit a beam of radiation and a collimator structure configured to limit a lateral extent of the beam, the collimator structure including a primary collimator configured to shape the beam, a first collimator comprising a plurality of adjacent elongate leaves, the leaves being extendable into the beam in a first direction transverse to the beam, and a block collimator including an aperture configured to permit the beam to pass through, the block collimator being extendable into the beam in a second direction transverse to the beam and transverse to the first direction. In some embodiments, the aperture may be cone-shaped or a through-hole, which may be empty or filled with a radiotransparent material. In some embodiments, the block collimator may include a plurality of apertures, which may be of varying dimensions.
G21K 1/04 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators using variable diaphragms, shutters, choppers
G21K 1/02 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators
The valve of an active breathing control (ABC) device can be driven by the output of the navigator channel of the MRI scanner, rather than by inference from a measured breath flow rate. Where the MRI scanner is integrated with a radiotherapy device, the MRI data can be used to trigger the enforced breath-hold by the ABC, and the radiotherapy delivered while the ABC valve is shut. If the MRI data pertains to the actual position of the tumor, then the ABC device will (in effect) hold the tumor at a precise and reproducible point for treatment.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A collimator for a radiotherapy apparatus comprising a block of radiation-attenuating material having a front face forming the leading edge of the block and at least one main rear face defining the trailing edge of the block, in which the least one main rear face has a material disposed thereon and is non-parallel to the front face. The collimator may form part of a radiotherapy apparatus, and methods of operation of such apparatus are described.
G21K 1/04 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators using variable diaphragms, shutters, choppers
G21K 1/02 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators
A fluorescing marker is used in order to mark (for example) a leaf of a multi-leaf collimator and/or the reference points within the field of view. The markers are illuminated with light tuned to cause the markers to fluoresce at a wavelength different to that of the illuminating light. The fluorescence is then detected by a camera. This method allows the image to be captured by the camera with increased contrast. Accordingly, the present invention provides a multi-leaf collimator for a radiotherapeutic apparatus, comprising at least one leaf having a fluorescent marker. The fluorescent marker will usually emit light of a wavelength longer than the incident light, allowing suitable filters to be provided in order to distinguish the light emitted by the markers. A suitable material for use in the fluorescent markers is ruby. The present invention also provides a radiotherapeutic apparatus comprising a multi-leaf collimator as defined above, and a camera arranged to view the fluorescent markers. A source of illumination for the fluorescent markers is ideally monochromatic, or nearly so. The camera can have a filter arranged to substantially prevent light of the wavelength emitted by the source of illumination from entering the camera, thereby improving the contrast of the image. The radiotherapeutic apparatus can also comprise a source of illumination that is optically co-located with a radiation source, to allow the radiation field that will be emitted to be checked visually by an operator. The co-located source is preferably substantially monochromatic, emitting substantially no light at the wavelength of the fluorescent markers. A filter can then be placed over an output of the radiotherapeutic apparatus, for blocking light of the wavelength of the fluorescent markers and thereby enhancing the contrast of the image that is taken of the fluorescent markers.
G21K 1/04 - Arrangements for handling particles or ionising radiation, e.g. focusing or moderating using diaphragms, collimators using variable diaphragms, shutters, choppers
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
In various embodiments, a system for controlling radiotherapy equipment in a treatment environment includes a controller for receiving, from one or more image capture devices, data indicating the position of one or more objects in the treatment environment. Based on the position data, the controller defines one or more exclusionary zones from which the radiotherapy equipment is excluded. Each zone has a buffer area surrounding one or more of the objects. The controller further directs the radiotherapy equipment such that a radiotherapy treatment plan is delivered without the equipment entering into the exclusionary zones.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A radiotherapy apparatus includes a rotatable drum on which is mounted a gantry arm carrying a radiation source. The arm extending from the drum to a location of the radiation source is offset from the axis of rotation of the drum and oriented towards the axis. The radiotherapy apparatus further includes a mechanism configured to apply a tilt to the arm at one or more rotational orientations of the drum. The rotatable drum is supported on wheels beneath the drum, and the mechanism is an eccentric mechanism within the wheels and is configured to apply the tilt to the arm via the wheels.
The disclosed systems and methods for Image-Guided Radiation Therapy (IGRT), utilizes an iterative approach which adjusts a treatment plan based on inter- or intra-fraction images to improve the accuracy of the radiation delivered during the overall treatment. The prescribed dose of radiotherapeutic radiation is mapped onto the patient's anatomy using an image acquired of the region, which is to be the target for radiotherapeutic radiation. Following beam-angle-optimization, fluence optimization and segmentation, the efficiency of delivery of each segment is determined using an objective function, and the segments ranked according to their efficiency. The plan proceeds with the choice of the most efficient segment (or segments) to be delivered first. When this radiation has been delivered, having been tracked to establish its distribution, this delivered distribution can be subtracted from the original prescribed dose and the process repeated so that the delivered radiation gradually converges on the original prescribed dose.
A method of calibrating a positioning system in a radiation therapy system which includes a radiation therapy unit having a fixed radiation focus, includes irradiating a calibration tool having at least one reference object, capturing at least one two-dimensional image including cross-sectional representations of reference objects of the calibration tool and determining image coordinates of the representation of each reference object. Based on the reference objects' image coordinates, positions of the reference objects in the stereotactic coordinate system relative to an origin of the calibration tool and the position of the origin of the calibration tool relative to the imaging unit, a position difference between the position of the calibration tool in the stereotactic coordinate system and a position of the calibration tool in an imaging system coordinate system including a translational and rotational position difference is calculated.
A radiotherapy system comprises a patient support, moveable along a translation axis, an imaging apparatus, comprising a first magnetic coil and a second magnetic coil, the first and second magnetic coils having a common central axis parallel to the translation axis, and being displaced from one another along the central axis to form a gap therebetween, the imaging apparatus being configured to obtain an image of a patient on the patient support, a source of radiation mounted on a chassis, the chassis being rotatable about the central axis and the source being adapted to emit a beam of radiation through the gap along a beam axis that intersects with the central axis, a multi-leaf collimator comprising a plurality of elongate leaves movable between at least a withdrawn position in which the leaf lies outside the beam, and an extended position in which the leaf projects across the beam, and a radiation detector mounted to the chassis opposite the source, the radiation detector having a plurality of detector elements aligned with the elongate leaves when projected onto an isocentric plane.
A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
A radiotherapy apparatus comprises a rotatable gantry, supporting a source of therapeutic radiation and a source of diagnostic radiation, the two sources being rotationally (or angularly) spaced apart around a rotation axis of the gantry, with at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a control means arranged to conduct a treatment fraction using the apparatus by causing the apparatus to i. acquire images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. subsequently, after further rotation of the gantry, select a retained image acquired when the source of diagnostic radiation was at a rotational position corresponding to the instantaneous rotational position of the source of therapeutic radiation, and iv. control the beam relative to the patient using information derived from the selected image. The corresponding rotational position is ideally one in which the source of therapeutic radiation is at the same or substantially the same rotational position as was the source of diagnostic radiation at the point in time when the image was acquired. An alternative a radiotherapy apparatus comprises a rotatable gantry supporting a source of therapeutic radiation and a source of diagnostic radiation, at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source, a reconstruction means arranged to i. obtain two-dimensional images of a patient using the source of diagnostic radiation, ii. retain those images at least temporarily, iii. apply a recency threshold to the retained images thereby to exclude images less recent than the threshold, iv. select at least three such retained images meeting the recency threshold and reconstruct a CT volume or tomographic image using the selected images, and a control means arranged to conduct a treatment fraction or treatment session using the apparatus, controlling the collimator using information derived from the CT volume.
An apparatus comprises a radiotherapy delivery apparatus having a radiation source for emitting a beam of radiation and wherein the source is rotatable around an axis intersecting the beam through a range of at least x degrees, an imaging device, and a control unit controlling the source and imaging device. The apparatus further comprises a treatment planning computer receiving a first image of a patient, and parameters defining the operations of the radiotherapy delivery apparatus. Parameters include an available range of rotation for the source, x-e, where e>0. The treatment planning computer generates a treatment plan for the patient based on the received image and parameters. The control unit determines a patient position using the imaging device, determines a rotation r of the patient around the axis relative to the first image, and compensates for the rotation by offsetting the source by a rotation, r, when r
Embodiments disclose a method performed by at least one processor for processing a plurality of x-ray projection images of a subject, the method comprising a plurality of operations including reconstructing the projection images to yield a volume reconstruction; segmenting the reconstructed volume by assigning a material type to each voxel; estimating a first set of scatter images corresponding to a subset of the projection images by calculating probabilistic predictions of interactions of x-rays with the subject and applying a low pass spatial filter to the scatter images; estimating a second set of scatter images corresponding to projection images not included in the subset, based on the first set of scatter images; and subtracting, for each projection image, the corresponding scatter image to yield a corrected projection image. Applying the plurality of operations of the method in an iterative process on graphics-processor-quality computational hardware enables real-time scatter correction and reconstruction of CT volume images.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for dose and fluence maps calculation and display for radiotherapy treatment: computer software for manipulation of medical systems and devices; Imaging software; data analytics software; Linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; Software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; Software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment. Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; MRI diagnostic apparatus; instruments and image guidance systems for stereotactic surgery; Stereotactic radio surgery equipment; fixtures and restraints for use in stereotactic surgery; medical equipment and instruments for non-invasive measurement of brain activity; test apparatus for medical purposes; radiology apparatus for medical purposes; apparatus for physiotherapy; collimators; and fixation apparatus for fixing limbs during measuring and treatment Brachytherapy treatment delivery systems, after-loaders, applicators and seed delivery apparatus and fittings; Magnetic Resonance Imaging equipment and apparatus; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; radiographic and x-ray equipment; X-ray tubes; X-ray imaging tubes for radiation technology; Radiation delivery devices; x-ray image intensifiers; accelerators for charged particles for therapeutic purposes; Ultrasonic scanners; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; Patient positioning systems, tools and manipulating apparatus and fixings; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging equipment; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels; parts and fittings for all the aforesaid goods. Medical education and user training; vocational guidance (non-business) in the field of medical, therapeutic, radiosurgical and radiotherapy techniques, appliances, apparatus and equipment; education and training on the use of image guided radiotherapy and image modulated radiation therapy, oncology, oncology information systems, stereotactic systems, brachytherapy equipment and solutions, software and planning tools; education and training on medical imaging techniques, apparatus and analysis; arranging and conducting of conferences, congresses and seminars relating to the design, use, test of medical and surgical apparatus and software for the medical treatment of cancer; education and training services for radiotherapy apparatus use, dosimetry planning and dose delivery in radiotherapy equipment. Design and development of computer hardware and software; computer programming; updating of computer software; remote software and data hosting services; cloud computing; electronic data storage and off site data back-up; design and development of medical equipment; Installation, maintenance and repair of software for computer systems; Computer software technical support services; Consultation services relating to computer software; Medical software planning and installation services; treatment room design and planning services for medical and radiotherapy delivery systems; Software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; Software as service for collecting analyzing and displaying medical images; Software as a service for medical analytics and informatics.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Computer software for use with medical treatment as well as with planning or simulation of medical treatment; computer software for handling, displaying, transmitting and transfer of patient data, information and medical images; computer software for the generation, capture, analysis and display of medical images including X-rays, Magnetic Resonance images (MR), Computed Tomography images (CT), cone beam Computed Tomography (CBCT) images, ultrasound images, positron emission tomography images, Single-photon emission computed tomography images (SPECT); Computer software for dose and fluence maps calculation and display for radiotherapy treatment: computer software for manipulation of medical systems and devices; Imaging software; data analytics software; Linear accelerator management and control software; MRI management and control software and analytics software; medical database software; treatment planning and workflow software; Software for cloud based services, data analytics and informatics; software for remote access allowing wireless connectivity; software for measuring and analyzing radiation dose delivery in radiosurgery and radiotherapy equipment; quality assurance software; calibration software; Software and computerized systems for management of clinical information and patient data, treatment delivery, patient record archiving and clinical charting; data and databases all recorded electronically, magnetically or optically; user, training and instruction manuals for the aforesaid goods, all provided in electronic form or downloadable from a computer network or the Internet; electronic publications; remote software applications; hardware and software for quality assurance and calibration measurements in medical and surgical equipment. Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; MRI diagnostic apparatus; instruments and image guidance systems for stereotactic surgery; Stereotactic radio surgery equipment; fixtures and restraints for use in stereotactic surgery; medical equipment and instruments for non-invasive measurement of brain activity; test apparatus for medical purposes; radiology apparatus for medical purposes; apparatus for physiotherapy; collimators; and fixation apparatus for fixing limbs during measuring and treatment; Brachytherapy treatment delivery systems, after-loaders, applicators and seed delivery apparatus and fittings; Magnetic Resonance Imaging equipment and apparatus; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; radiographic and x-ray equipment; X-ray tubes; X-ray imaging tubes for radiation technology; Radiation delivery devices; x-ray image intensifiers; accelerators for charged particles for therapeutic purposes; Ultrasonic scanners; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; Patient positioning systems, tools and manipulating apparatus and fixings; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging equipment; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels; parts and fittings for all the aforesaid goods. Medical education and user training; vocational guidance (non-business) in the field of medical, therapeutic, radiosurgical and radiotherapy techniques, appliances, apparatus and equipment; education and training on the use of image guided radiotherapy and image modulated radiation therapy, oncology, oncology information systems, stereotactic systems, brachytherapy equipment and solutions, software and planning tools; education and training on medical imaging techniques, apparatus and analysis; arranging and conducting of conferences, congresses and seminars relating to the design, use, test of medical and surgical apparatus and software for the medical treatment of cancer; education and training services for radiotherapy apparatus use, dosimetry planning and dose delivery in radiotherapy equipment. Design and development of computer hardware and software; computer programming; updating of computer software; remote software and data hosting services; cloud computing; electronic data storage and off site data back-up; design and development of medical equipment; Installation, maintenance and repair of software for computer systems; Computer software technical support services; Consultation services relating to computer software; Medical software planning and installation services; treatment room design and planning services for medical and radiotherapy delivery systems; Software as a service for or use in medical treatment as well as with planning or simulation of medical treatment; software as a service for handling, displaying and transfer of patient data, information and images; Software as service for collecting analyzing and displaying medical images; Software as a service for medical analytics and informatics.
41 - Education, entertainment, sporting and cultural services
Goods & Services
Medical and surgical apparatus and instruments; apparatus and instruments for use with medical analysis for identification, planning as well as implementing of treatment against cancer, benign diseases or neurological disorders using radiation; radiosurgery and radiotherapy equipment, apparatus and instruments; Image guided radiation therapy device for use in medicine and computer software and hardware sold as a unit therewith; MRI diagnostic apparatus; instruments and image guidance systems for stereotactic surgery; Stereotactic radio surgery equipment; fixtures and restraints for use in stereotactic surgery; medical equipment and instruments for non-invasive measurement of brain activity; test apparatus for medical purposes; radiology apparatus for medical purposes; apparatus for physiotherapy; collimators; and fixation apparatus for fixing limbs during measuring and treatment; Brachytherapy treatment delivery systems, after-loaders, applicators and seed delivery apparatus and fittings; Magnetic Resonance Imaging equipment and apparatus; Medical and radiographic Linear Accelerators; Radiation beam collimation apparatus for radiotherapy; Magnetoencephalography imaging equipment; radiographic and x-ray equipment; X-ray tubes; X-ray imaging tubes for radiation technology; Radiation delivery devices; x-ray image intensifiers; accelerators for charged particles for therapeutic purposes; Ultrasonic scanners; medical imaging apparatus for the creation or transmission of images, video or data relating to a medical treatment for diagnostic or clinical use; surgery, therapy, medical treatment and operating tables, beds and couches; special furniture for medical use; Patient positioning systems, tools and manipulating apparatus and fixings; patient restraints; Imaging and treatment simulation apparatus for treatment planning and simulation; medical imaging equipment; X-ray radiographic and fluoroscopic imaging systems, receivers and transmitter panels; parts and fittings for all the aforesaid goods. Medical education and user training; vocational guidance (non-business) in the field of medical, therapeutic, radiosurgical and radiotherapy techniques, appliances, apparatus and equipment; education and training on the use of image guided radiotherapy and image modulated radiation therapy, oncology, oncology information systems, stereotactic systems, brachytherapy equipment and solutions, planning tools; education and training on medical imaging techniques, apparatus and analysis; arranging and conducting of conferences, congresses and seminars relating to the design, use, test of medical and surgical apparatus for the medical treatment of cancer; education and training services for radiotherapy apparatus use, dosimetry planning and dose delivery in radiotherapy equipment.
A patient support includes a bed, one or more mechanisms configured for manipulating at least one of position and orientation of the bed, and a display configured for displaying a user interface and receiving inputs to control at least the one or more mechanisms.
G06Q 50/24 - Patient record management (processing of medical or biological data for scientific purposes G06F 19/00)
A61B 90/98 - Identification means for patients or instruments, e.g. tags using electromagnetic means, e.g. transponders
A61B 6/04 - Positioning of patients; Tiltable beds or the like
G06K 17/00 - Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups , e.g. automatic card files incorporating conveying and reading operations
A61B 90/90 - Identification means for patients or instruments, e.g. tags
