Goods & Services

clothing, namely, shirts, sweatshirts, jackets, shorts, sweatpants, socks, hats and backpacks Educational and Entertainment services, namely, providing course instruction at the university level; arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes; arranging and conducting educational conferences Scientific Research medical clinic services

Goods & Services

clothing, namely shirts, shorts, pants, hats; cups and mugs

Goods & Services

clothing, namely, hats, shirts and jerseys

Goods & Services

Educational services, namely, providing instruction in the field of business and entrepreneurship; fostering business-academic collaborations and investments in the commercialization of university-based technologies

Goods & Services

Educational and entertainment services, namely, providing course instruction and tutoring at the university level; arranging exhibitions for entertainment and educational purposes; arranging and conducting educational conferences in the field of world languages

Goods & Services

Educational services, namely, providing facilities for and instruction in the field of business and entrepreneurship, fostering business-academic collaborations, and conducting research and community outreach programs

Goods & Services

entertainment services, namely, arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes

Goods & Services

Clothing, namely, tops as clothing, jackets and shirts

Goods & Services

Educational services, namely, providing course instruction at the university level in the field of sensing and embedded network systems engineering Providing academic research in the field of sensing and embedded network systems engineering

Goods & Services

Educational services, namely, providing course instruction in the field of sensing and embedded network systems engineering

Goods & Services

Educational services, namely, providing instruction in the field of sensing and embedded network systems engineering

Goods & Services

arranging and conducting collegiate athletic and sporting events

Goods & Services

clothing, namely, shirts, sweatshirts, jackets, shorts, sweatpants, socks, hats and backpacks

Goods & Services

Medical clinic services

Goods & Services

Educational [ and Entertainment ] services, namely, providing course instruction at the university level; [ arranging and providing collegiate athletic and sporting events; ] arranging exhibitions for [ entertainment and ] educational purposes; arranging and conducting educational conferences [ scientific research; academic research in the field of the medical sciences ]

Abstract

A method for feeding larval fish in an artificial habitat having a water level, includes the step of providing in the habitat a plurality of light sources at a plurality of three dimensional locations in the habitat and below the water level. Inanimate food particles are placed into the water. The plurality of lights are pulsed at the plurality of three dimensional locations intermittently to illuminate the food particles from a variety of different angles within the habitat. A system for feeding fish, a habitat for fish, and a larval fish food are also disclosed.

IPC Classes  ?

• A01K 61/00 - Culture of aquatic animals
• A01K 63/00 - Receptacles for live fish, e.g. aquariaTerraria
• G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
• H05B 33/00 - Electroluminescent light sources

Abstract

Compositions for inhibiting replication of a virus in a subject (e.g., a human patient) infected with the virus or at risk of being infected with the virus include a therapeutically effective amount of SRSF1 protein, a portion of a SRSF1 protein, or a nucleic acid encoding the SRSF1 protein or a portion thereof, and a pharmaceutically acceptable carrier. Methods of using these compositions, and kits including these compositions, are also described herein. These compositions, kits and methods provide novel therapies for AIDS based on the delivery of SRSF1, single protein domains (portions) derived from SRSF1, and compounds mimicking the activity of such domains.

IPC Classes  ?

• A61P 31/18 - Antivirals for RNA viruses for HIV
• C07K 14/155 - Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
• C07K 14/16 - HIV-1
• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

Goods & Services

Clothing, namely, shirts, sweatshirts, [ shorts and ] pants; and headgear, namely, hats; footwear

Goods & Services

Clothing, namely, shirts, sweatshirts, shorts and pants; and headgear, namely, hats

Goods & Services

Educational and Entertainment services, namely, providing course instruction at the university level; academic research; arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes; arranging and conducting educational conferences

Goods & Services

Clothing, namely, shirts, sweatshirts, pants and shorts; headgear, namely, hats

Goods & Services

Educational and Entertainment services, namely, providing course instruction at the university level; academic research; arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes; arranging and conducting educational conferences

Goods & Services

Clothing, namely, shirts, sweatshirts, pants and shorts; footwear, headgear, namely, hats

Goods & Services

Educational and Entertainment services, namely, providing course instruction at the university level; academic research; arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes; arranging and conducting educational conferences

Goods & Services

Educational services, namely, providing course instruction at the university level

Goods & Services

Clothing, namely, sweatshirts, shirts, pants, shorts; footwear; headgear, namely, hats Educational and Entertainment services, namely, providing course instruction at the university level; arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes

Goods & Services

Clothing, namely, sweatshirts, shirts, pants, socks; headgear, namely, hats; footwear Educational and entertainment services, namely, providing course instruction at the university level; arranging and providing collegiate athletic and sporting events

Abstract

Secure data processing is described. Particular systems and methods involve enrollment units and methods, where the method includes obtaining an input data representing a raw data associated with a user, generating a template for the input data, and storing the template in an enrollment database, optionally with an identifier for the user. Other systems and method involve comparison or authentication units or methods, where the method involves obtaining templates corresponding to data sets to be compared, comparing the templates using a pre-defined comparison function to yield a similarity measure, and if the similarity measure meets a similarity criterion, determining that the data sets are from the same source. In the systems and methods, the templates are secure and noise tolerant templates configured to reveal limited features of the data set and to prevent reconstruction of the data set from the template.

IPC Classes  ?

• G06F 21/32 - User authentication using biometric data, e.g. fingerprints, iris scans or voiceprints

Goods & Services

Educational services, namely, an undergraduate research and entrepreneurship competition

Goods & Services

Clothing, namely, T-Shirts, Hats, Caps Miniature toy helmets

Goods & Services

Educational and entertainment services, namely, providing course instruction at the university level; arranging and providing collegiate athletic and sporting events; arranging exhibitions for entertainment and educational purposes; arranging and conducting educational conferences Academic research, namely, scientific and medical research

Goods & Services

Retail services, namely, a retail gift shop featuring apparel, personal and household accessories, books related to marine life Conducting marine and aquatic tours to the public Education in the nature of conducting marine classes and conferences in the field of marine exploration and discovery, marine ecosystem health, marine resource utilization, and technology for ocean science Scientific research, namely, marine research in the field of marine exploration and discovery, marine ecosystem health, marine resource utilization, and technology for ocean science

Abstract

Biomarkers specific in the prognosis or diagnosis of different clinical stages of chronic inflammatory disease are identified by proteins associated with phagocytosed chitin microparticles (PAPC), Identification of these biomarkers provide for discovery of new therapies as well as monitoring of a therapy in a patient.

IPC Classes  ?

• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 9/14 - Particulate form, e.g. powders

Abstract

A system that incorporates teachings of the present disclosure may include, for example, a syntactic component for retrieving records corresponding to an individual and analyzing the records to assess a condition for the individual; a user interface for capturing interaction data that is associated with an encounter between the individual and a service provider; and a semantic component for comparing the interaction data to interaction criteria, where an action plan for the individual is generated based at least in part on the assessed condition and the comparison of the interaction data to the interaction criteria. Other embodiments are disclosed.

IPC Classes  ?

• G06Q 50/00 - Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism

Abstract

A system and method of analyzing at least one dataset having temporal and spatial content is provided. A method includes the steps of applying a colorimetric mapping to the dataset based on the spatial content (500), segmenting the dataset (618) into one of a plurality of patterns based on a spatio-temporal analysis of the dataset (604, 606), and analyzing characteristics of each of the plurality of patterns (612-622).

IPC Classes  ?

• G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
• G06F 17/00 - Digital computing or data processing equipment or methods, specially adapted for specific functions

Abstract

Artificial (e.g., synthetic) carbohydrate receptors that specifically bind sialic acid and cancer cell surface carbohydrate antigens containing terminal sialic moieties (e.g., Lewis oligosacharide antigens) and methods of use were developed. The artificial carbohydrate receptors and methods can be used to detect and identify biologically important carbohydrates, selectively label cancer cells, to modulate cancer cell growth, and to modulate inflammation. Because the artificial carbohydrate receptors demonstrate a strong affinity for sialylated Lewis oligosacharide antigens (e.g., sialyl Lewis x (sLex) and sialyl Lewis a (sLea)) which are overexpressed on tumor cells during the onset and progression of cancer, and are overexpressed on the endothelium of chronically inflamed tissues, the artificial carbohydrate receptors described herein can find use as cancer diagnostic and therapeutic agents.

IPC Classes  ?

• A01N 43/02 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom

Abstract

A composition and method for the preparation of micro-particles of chitin (a naturally occurring polymer of N-acetyl-D-glucosamine), the characterization of chitin micro-particles as an immune adjuvant and the use of chitin micro-particles to enhance protective immunity against intracellular infectious agents and diseases as well as to inhibit allergic responses and diseases.

IPC Classes  ?

• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61K 31/722 - ChitinChitosan
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
• A61K 31/724 - Cyclodextrins
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

The invention provides compositions comprising sulindac, R-epimer sulindac, S-epimer sulindac, derivatives, metabolites, and structural analogs thereof which protect normal cells against damage caused by solar rays, oxidative damage, environmental factors, diseases and organisms.

IPC Classes  ?

• A61K 31/255 - Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
• A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
• A61P 17/18 - Antioxidants, e.g. antiradicals

Abstract

A method of measuring the susceptibility of a subject to calcifying nanoparticle formation is disclosed. The method can include obtaining a cell culture comprising peripheral blood mononuclear cells, immune cells, or both, from a peripheral blood mononuclear fraction of a subject in a complete culture media; extracting a first aliquot and a second aliquot from the cell culture; and dispensing the first and second aliquot in different wells. The surface of the well containing the first aliquot can include a calcifying nanoparticle biofilm, while the well containing the second aliquot does not. The first and second aliquots can be incubated and the concentration of osteopontin in each aliquot determined. An osteopontin factor can be calculated and compared to osteopontin factors from a representative sample of other subjects. The osteopontin factor can be defined as the osteopontin concentration in the first aliquot divided by the osteopontin concentration in the second aliquot.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

Abstract

A method of characterizing calcifying nanoparticles (CNPs) can include creating a test sample comprising CNPs isolated from a biological source, a buffer solution, a plurality of calibration beads, and a fluorescent marker specifically linked to the CNPs; evaluating the test sample using a flow cytometer; and analyzing results from the flow cytometer to determine a characterizing feature of the calcifying nanoparticles. The characterizing feature of the calcifying nanoparticles can be the number of CNPs, concentration of CNPs, size of CNPs, level of CNP aggregation, size and light dispersion characteristics of CNPs, fluorescence intensity of the CNPs when labeled with a specific antibody, or a combinations thereof. The method can also include evaluating an isotype control comprising CNPs isolated from the biological source, the buffer solution, a plurality of calibration beads, and a fluorescent marker that is not linked to the CNPs.

IPC Classes  ?

• G01N 33/533 - Production of labelled immunochemicals with fluorescent label
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

Abstract

Microfluidic chips, systems including at least one integrated microfluidic chip operably connected to hardware (e.g., docking device, high voltage electrodes, portable fluorescence microscope, computer, etc.), and methods for analyzing peptides (e.g., toxins), proteins (e.g., cancer biomarkers, recombinant human growth hormone, recombinant human erythropoietin), and protein expression in biological samples (e.g., human serum, urine, or tissue, marine organism, seafood, etc.) have been developed. On a single microfluidic chip as described herein, several sequential processes for analyzing a protein (e.g., cell culturing, cell lysis, protein enrichment, protein labeling, and protein detection) can be performed in an automated fashion. The microfluidic chips, systems, and methods described herein provide real-time, high-throughput, highly-specific detection of proteins such as recombinant erythropoietin, recombinant human growth hormone and marine biotoxins, as well as important biomarkers in the cancer signaling pathway network for early and precise cancer diagnosis.

IPC Classes  ?

• B01D 57/02 - Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. by electrophoresis
• B01D 59/42 - Separation by electrochemical methods by electromigrationSeparation by electrochemical methods by electrophoresis
• B01D 59/50 - Separation involving two or more processes covered by different groups selected from groups , , , , , , , ,
• B01D 61/42 - ElectrodialysisElectro-osmosis

Abstract

Compositions and methods for protecting neural tissue (e.g., neurons) from anoxia and spreading depression (SD) involve inhibiting the cGMP-dependent protein kinase (PKG) pathway. It was discovered that the PKG pathway plays a crucial role in regulating SD and tolerance to anoxia in the central nervous system (CNS). Inhibition of the PKG pathway greatly reduces SD and increases tolerance to anoxia (i.e., hypoxia), while activation of the pathway exacerbates SD pathology. The compositions and methods can be used to treat any condition associated with SD or anoxia, including stroke, spinal cord injury, neurogenerative disease, dizziness, headaches, and migraines.

IPC Classes  ?

• A61K 38/00 - Medicinal preparations containing peptides
• A61K 31/50 - PyridazinesHydrogenated pyridazines
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61P 25/02 - Drugs for disorders of the nervous system for peripheral neuropathies
• A61P 23/00 - Anaesthetics
• A01N 43/58 - 1,2-DiazinesHydrogenated 1,2-diazines
• A01N 43/60 - 1,4-DiazinesHydrogenated 1,4-diazines

Abstract

Compositions and methods for protecting neural tissue (e.g., neurons) from anoxia and spreading depression (SD) involve inhibiting the cGMP-dependent protein kinase (PKG) pathway. It was discovered that the PKG pathway plays a crucial role in regulating SD and tolerance to anoxia in the central nervous system (CNS). Inhibition of the PKG pathway greatly reduces SD and increases tolerance to anoxia (i.e., hypoxia), while activation of the pathway exacerbates SD pathology. The compositions and methods can be used to treat any condition associated with SD or anoxia, including stroke, spinal cord injury, neurogenerative disease, dizziness, headaches, and migraines.

IPC Classes  ?

• A01N 43/04 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom
• A61K 31/70 - CarbohydratesSugarsDerivatives thereof
• A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings

Abstract

The invention relates to the discovery that in an animal model of Parkinson's disease (PD), administration of granulocyte colony- stimulating factor (G-CSF) to rodents having 1-methyl~4-phenyl-1,2,3,6-tetrahydropy꧀d蹡ne (MPTP)-蹡nduced PD restores the function of dopamine neurons G-CSF treatment is found to increase the number of dopamine neurons In the substantia nigra (SN), partially restore the nigrost꧀atal pathway, and restore the function of dopamine to the level before MPTP treatment The invention also relates to the discovery that treatment of a human patient having corticobasilar ganglionic degeneration, or a patient who had suffered an acute stroke, with G-CSF results in a significant improvement in the patient's Unified Parkinson's Disease Rating Scale evaluations and neurological function, respectively The methods described herein can be used to treat PD in a mammalian subject, as well as other neurodegenerative diseases such as Alzheimer's disease, spinal cord injury, and stroke

IPC Classes  ?

• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups

Abstract

Clonal strains of bacteria derived from Pseudopterogorgia elisabethae are capable of making pseudopterosins in in vitro cultures without requiring the presence of other bacteria, algae, or animal cells that are normally present in P. elisabethae.

IPC Classes  ?

• C12N 1/20 - BacteriaCulture media therefor
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
• C12P 19/56 - Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
• C40B 40/02 - Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cellsLibraries contained in or displayed by vectors, e.g. plasmidsLibraries containing only microorganisms or vectors
• C07H 15/24 - Condensed ring systems having three or more rings
• C12N 15/01 - Preparation of mutants without inserting foreign genetic material thereinScreening processes therefor
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

A method for receiving encoded MPEG-2 video signals and transcoding the received encoded signals to encoded H.264 reduced resolution video signals, including the following steps: decoding the encoded MPEG-2 video signals to obtain frames of uncompressed video signals and to also obtain MPEG-2 feature signals; deriving H.264 mode estimation signals from the MPEG-2 feature signals; subsampling the frames of uncompressed video signals to produce subsampled frames of video signals; and producing the encoded H.264 reduced resolution video signals using the subsampled frames of video signals and the H.264 mode estimation signals.

IPC Classes  ?

• H04N 7/26 - using bandwidth reduction (information reduction by code conversion in general H03M 7/30)

Goods & Services

research services in the field of ocean science

Abstract

A visual image retrieval system is provided. The system includes an image database for storing images. A preprocessor communicatively linked to the image database for segmenting the images and generating based upon segmented images a region-of- interest (ROI) extraction output. A perceptually-relevant image search machine (PRISM) interface for displaying query images and retrieved images, the retrieved images being retrieved in response to a user selecting at least one displayed query image. A search-and -retrieval module for searching and retrieving stored images for display with the PRISM interface in response to a user selecting at least one displayed query image, and a global/ROI search module for selecting between a global search or an ROI search if more than one query image is selected, and for trigging the selected search.

IPC Classes  ?

• G06F 7/00 - Methods or arrangements for processing data by operating upon the order or content of the data handled

Abstract

A composition and method for the preparation of micro-particles of chitin (a naturally occurring polymer of N-acetyl-D-glucosamine), the characterization of chitin micro-particles as an immune adjuvant and the use of chitin micro-particles to enhance protective immunity against intracellular infectious agents and diseases as well as to inhibit allergic responses and diseases.

IPC Classes  ?

• A01N 43/04 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom
• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof

Abstract

A method for compressing and transmitting a sequence of video frames represented by arrays of digital pixel values includes the following steps: transmitting a representation of a first frame (h) of the sequence; deriving a sorting permutation P1 of the first frame; using the sorting permutation of the first frame, P1, to approximately sort a second frame (I2) of the sequence, to obtain approximately sorted frame P1(I2); and compressing and transmitting the approximately sorted frame P1(I2).

IPC Classes  ?

• H04N 7/167 - Systems rendering the television signal unintelligible and subsequently intelligible

Abstract

The present invention relates to the use of MT as a reducing system for the Msr enzymes and other oxioreductase enzymes which form similar intermediates. Specifically, the invention provides for a reduction in the level of oxidative damage in cells through an increase in levels of MT by administration of suitable compounds, resulting in an increase in the activity of the Msr enzymes.

IPC Classes  ?

• A61K 38/42 - HaemoglobinsMyoglobins

Abstract

Synthetic triple-helical peptides (THPs) are used for the design and synthesis of triple- helical transition state analog inhibitors. These inhibitors feature a phosphonate ester or phosphinic moiety in place of the scissle bond. These groups inhibit MMPs, and methods been developed for their convenient incorporation within a peptide sequence by solid-phase methods.

IPC Classes  ?

• A61K 31/4035 - Isoindoles, e.g. phthalimide
• C07D 403/02 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings

Abstract

The identification and characterization of the sources of terpenes from the soft corals Leptogorgia minimata (LM, formerly Lophogorgia spp., Family: Gorgoniidae), Swifita exertia (SE, Family: Plexauridae), Iciligorgia schrammi (IS, Family: Anthothelidae), Eunicea fusca, Eiythropodium caribaeorum or Plexaurella sp. through direct culture of microbial populations derived from coral homogenates.

IPC Classes  ?

• C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
• C12P 7/02 - Preparation of oxygen-containing organic compounds containing a hydroxy group
• C07C 403/00 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone

Abstract

A method of multi-view video coding is provided. The method includes generating a multiple-view compressed encoded data sequence, sequence being generated by encoding a plurality of video signals. Each video signal defines a distinct camera view of one of a plurality of cameras. The encoding is based on a hypercube prediction structure formed by multiple nodes that each node represent a distinct camera view. The method also includes conveying the compressed encoded data sequence over a data communication network connection, and presenting a visual display. The visual display is presented by decoding the compressed encoded data sequence, the decoding being based upon the hypercube prediction structure.

IPC Classes  ?

• H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast

Abstract

A new family Here we report a new family of four-cystine/three-loop conotoxins (designated framework 14). Three peptides of this family (flfl4a-c) were isolated from the venom of Conus floridanus floridensis and one (vill4a) from the venom of Conus villepinii, two worm-hunting Western Atlantic cone snail species. CD spectra and nanoNMR spectroscopy of these conotoxins directly isolated from the cone snails revealed a highly helical secondary structure for the four conotoxins. Sequence-specific nanoNMR analysis at room temperature revealed a well-defined helix-loop-helix tertiary structure that resembles that of the Cs &agr;/&agr; scorpion toxins κ-hefutoxin, K-KTx1.3 and Om-toxins, which adopt a stable three-dimensional fold where the two &agr;-helices are linked by the two disulfide bridges. One of these conotoxins (vill4a) has a Lys/Tyr (or Phe) diad, separated by approximately 6Å, which is a conserved structural feature in K+ channel blockers.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

Goods & Services

educational services at the university level

Goods & Services

Education Services At The University Level

Goods & Services

Educational services at the University level

Goods & Services

educational services in the nature of courses at the university level

Goods & Services

Educational services in the nature of aqua and marine training and demonstration

Goods & Services

Board games, playing cards, Christmas tree ornaments, and plush toys Metal key chains, metal license plates, and non-luminous and non-mechanical metal signs [ Football helmets ] License plate frames Jewelry and cuff links [ Writing paper, pens, pencils, and souvenir sports programs ] [ Leather key chains, and ] athletic bags Picture frames, and non-metal key chains Drinking glasses, and decorative plates Blankets, namely, bed blankets and blanket throws; cloth flags, and cloth banners Clothing, namely, T-shirts, sweatshirts, shorts, sweatpants, jackets, and hats

Goods & Services

jewelry [ and cuff links ]