A61K 31/4725 - Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
A61K 31/195 - Carboxylic acids, e.g. valproic acid having an amino group
A61K 31/4409 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
A61K 31/4436 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
A61P 25/04 - Centrally acting analgesics, e.g. opioids
C07D 213/68 - One oxygen atom attached in position 4
C07D 213/74 - Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 409/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
An extrusion device for manufacturing a hollow structure by coaxial extrusion of a plurality of media. The extrusion device has a plurality of mountings, each for a nozzle for extruding one of the media. The mountings extend in an axial direction along a central axis and are arranged coaxially, for coaxial arrangement of the nozzles in one another. At least two of the mountings follow one another in a radial direction and are mounted against one another in the radial direction by use of a bearing such that the at least two mountings can be displaced relative to one another in the axial direction in order to adjust the relative axial positions of the respective nozzles.
The invention provides an apparatus and a method for generating a perfusion image, as well as a method for training an artificial neural network for use therein. The method comprises at least steps of: receiving (S100) at least one non-contrast medical diagnostic image. NCMDI (1-i), acquired from organic tissue: generating (S200), using an artificial neural network. ANN (2), trained and configured to receive input data (10) based on at least one of the received at least one non-contrast medical diagnostic image, NCMDI (1-i), based on the input data (10), at least a perfusion image (3) for the organic tissue shown in the at least one non-contrast medical diagnostic image, NCMDI (1-i); and outputting (S300) at least the generated perfusion image (3).
A method (500) for conditioning or hydrolysis of an extruded membrane is disclosed. The method (500) comprising ion exchange processes in divided electrochemical cells using a cation exchanger membrane. The method (500) includes extruding the perfluorosulfonyl fluoride membranes from perfluorosulfonyl fluoride granulate. The method (500) also includes using a pretreatment technique to increase the ionic conductivity of the extruded perfluorosulfonyl fluoride membranes before using the perfluorosulfonic acid membranes in electrolysis cells. The method (500) also includes applying a milder pretreatment technique by activating S—F bonds to execute nucleophilic exchange of the fluoride group in a reaction. The method (500) also includes hydrolyzing sulfonyl fluoride groups to sulfonic acid using triethylsilanol.
A computer-implemented method identifies an operation parameter of an industrial process as a candidate for modification so that the process can continue even of the material at the input of the process changes. In simulation instances, the computer receives representations of the material and of operation parameters and provides a representation of the would-be product. The computer classifies the instances into first and second quality classes. The computer continues by clustering—separated by parameters—the instances according to parameter attributes and according to the first and second quality classes. The computer repeats the simulation with variations that are related to significant differences, and identifies the candidate for modification.
This application provides methods and apparatuses for encoding image or video related data into a bitstream. The present disclosure may be applied in the field of artificial intelligence (AI)-based video or picture compression technologies, and in particular, to the field of neural network-based video compression technologies. A neural network (generalized difference) is applied to a signal and a predicted signal during the encoding to obtain a generalized residual. During the decoding another neural network (generalized sum) may be applied to a reconstructed generalized residual and the predicted signal to obtain a reconstructed signal.
H04N 19/20 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using video object coding
H04N 19/587 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using predictive coding involving temporal sub-sampling or interpolation, e.g. decimation or subsequent interpolation of pictures in a video sequence
7.
Method for Manufacturing a Component by Means of Layered Construction
The invention relates to a method for producing a component by means of layered construction, by combining a plurality of crystallites of a metallic material to form a single crystal. The single crystal is formed by thermomechanically activated successive anisotropic plastic deformation. The metallic material is heated during the construction of a new layer, with the result that the metallic material is melted in a linear region. The linear region is moved in order to construct the new layer.
The application describes a T-cell expressing a chimeric antigen receptor (‘CAR T-cell’) containing superparamagnetic iron-based particles (‘loaded CAR T-cell’) for use in treating a tumor. Said loaded CAR T-cell exhibits a reduced cytokine release upon binding to a cell of the tumor expressing an antigen being recognized by the CAR of the CAR T-cell, compared to a CAR T-cell not containing superparamagnetic iron-based particles (‘unloaded CAR T-cell’) under the same conditions. Furthermore, an in vitro method of generating a CAR T-cell containing superparamagnetic iron-based particles is described, whereby such loaded CAR T-cells are generated.
A61K 51/12 - Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
A61K 39/00 - Medicinal preparations containing antigens or antibodies
Large-signal inductance measuring device for performing a measuring operation for measuring an inductance at an electrical energy supply line arrangement operated with a DC voltage, the large-signal inductance measuring device including: a disconnecting switch for electrically disconnecting the first conductor of the energy supply line arrangement; a first series circuit including a first capacitive arrangement and a first diode arrangement; a first measuring device for measuring a first change in voltage after the first conductor is disconnected; a second series circuit including a second capacitive arrangement and a second diode arrangement; a second measuring device for measuring a second change in voltage after the first conductor is disconnected; a third measuring device for measuring a third current on the first conductor before the first conductor is disconnected; and an evaluation device for evaluating the measured first change in voltage, the measured second change in voltage, and the measured third current.
G01R 27/26 - Measuring inductance or capacitanceMeasuring quality factor, e.g. by using the resonance methodMeasuring loss factorMeasuring dielectric constants
10.
METHOD FOR UPDATING RISK ANALYSIS PARAMETERS OF A TECHNICAL SYSTEM
A computer-based method for updating risk analysis parameters of a proactive risk analysis of a technical system, such as of an FMEA analysis for example. The method uses incident report data obtained during posterior operation of the technical system, compares these incident report data with data of the proactive risk analysis, and updates the said risk analysis parameters in function of said comparison.
An apparatus comprising a six-port circuit, a delay device, and a computing device, wherein the delay device is adapted to divide an input signal into a first input signal and a second input signal, to delay the first input signal by a first delay time, wherein, for example, a first delayed input signal is obtained, to delay the second input signal by a second delay time, wherein, for example, a second delayed input signal is obtained, the second delay time being different from the first delay time, wherein the delay device is adapted to output the first delayed input signal to a first input of the six-port circuit, and to output the second delayed input signal to a second input of the six-port circuit, wherein the computing device is adapted to determine a first quantity characterizing a frequency of the input signal in dependence on at least one output signal of the six-port circuit.
Immobilization and magnetic extraction of pathogens and pathogen components The application describes a method for reducing the concentration of pathogens and/or pathogen components in an aqueous or body fluid sample. Specifically, the method relates to incubating the sample with superparamagnetic iron-based particles attached to a target binding peptide and immobilising the superparamagnetic iron-based particles with a magnetic field and thereby separating the pathogen-bound and/or pathogen component-bound superparamagnetic iron-based particles from the sample. Furthermore, the application relates to a method for identifying pathogens in an aqueous or body fluid sample a use of superparamagnetic iron-based particles for reducing the concentration of pathogens and/or pathogen components in an aqueous or body fluid sample. In addition, a use of superparamagnetic iron-based particles for identifying pathogens in an aqueous or body fluid sample is disclosed. Finally, superparamagnetic ironoxide nanoparticles (SPION's) are disclosed, wherein the SPIONs are linked to a target binding peptide. wherein the target is a pathogen, and/or a pathogen component.
A sparse motion field exchanges motion information between encoder and decoder. Side information indicates a suitable interpolation approach for interpolating the motion vectors of the dense motion field different from the signaled sparse motion field motion vectors. The side information is provided on a segment basis. The segments are derived at the encoder side and the decoder side similarly, based on the reference images and the sparse motion field.
Brandenburgische Technische Universität Cottbus-Senftenberg (Germany)
Inventor
Müller, Ralf R.
Rosenberger, Hans
Reichenbach, Marc
Abstract
An apparatus computing a matrix vector product of a given matrix, wherein the given matrix is represented by S submatrices, with S□1, with each submatrix representing a vertical slice of the given matrix, and with each submatrix approximated by the product of P further matrices, with P□1. Each further matrix is a sparse matrix and includes in each row a certain number of elements unequal to zero. The apparatus has S processing chains, wherein each processing chain is to receive an arbitrary vector and comprises P processing blocks. Each processing block is to multiply a block input vector and an associated further matrix by shifting the elements of the block input vector according to the values of the elements in the associated further matrix which are unequal to zero, and by combining the shifted elements of the block input vector to obtain respective elements of a block output vector.
G06F 5/01 - Methods or arrangements for data conversion without changing the order or content of the data handled for shifting, e.g. justifying, scaling, normalising
15.
Bone Morphogenetic Protein-8B (BMP8B) as marker and therapeutic target for liver fibrosis or liver cancer
The present invention refers to BMP8B-inhibitor for use in a method of preventing and/or treating liver fibrosis and/or liver cancer, wherein the inhibitor is an oligonucleotide, an antibody or fragment thereof, a small molecule or a combination thereof. Further, the invention is directed to a method for diagnosing liver fibrosis and/or liver cancer and a kit for diagnosing fibrosis and/or cancer. The method and the kit can be used to identify a subject in need for a BMP8B-inhibitor to prevent and/or treat liver fibrosis and/or liver cancer.
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
Provided herein is the use of a soluble form of a member of the CD83 family of proteins (sCD83) for wound healing, including hard-to-heal wounds of elderly, diabetic, or patients under immunosuppressant medication. Further provided is the therapeutic use of the sCD83 for the systemic promotion of hair growth, after physical stress/medication, disease and/or depilation by application of systemic sCD83, and cosmetic methods for skin and hair care comprising the topical application of sCD83.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
A61Q 7/00 - Preparations for affecting hair growth
A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
17.
Crystal Growing Unit for Producing a Single Crystal
The invention relates to a crystal growing unit comprising a crucible for producing and/or enlarging a single crystal. The crystal growing unit has a first thermal insulation with a first thermal conductivity and a second thermal insulation with a second thermal conductivity. The crucible has a crucible base, a crucible side wall and a crucible cover. The crucible side wall is indirectly or directly surrounded by the first thermal insulation. The second thermal insulation is arranged indirectly or directly above the crucible cover. The second thermal conductivity is greater than the first thermal conductivity.
C30B 35/00 - Apparatus not otherwise provided for, specially adapted for the growth, production or after-treatment of single crystals or of a homogeneous polycrystalline material with defined structure
18.
PARTICLE DISPERSION AND PROCESS FOR FORMING A PARTICLE DISPERSION
The present invention relates to a process for producing a particle dispersion comprising the steps of: a) providing a dispersion consisting of a solvent and solid core particles, b) providing a solution of a soluble, interfacially-active polymer having a molecular weight of more than 5 kDa, c) mixing said dispersion of solid core particles with said polymer solution, d) removing free polymer from the obtained mixture; wherein in step a) the solvent is selected from an organic solvent, a mixture of at least two organic solvents or a mixture of at least one organic solvent with water; wherein in step c), the amount of the soluble, interfacially-active polymer mixed with said dispersion of solid core particles exceeds the amount of polymer required to coat the surface of each of the solid core particles with a monolayer of the polymer; wherein step d) is repeated until the requirement described by the following formula is fulfilled:
The present invention relates to a process for producing a particle dispersion comprising the steps of: a) providing a dispersion consisting of a solvent and solid core particles, b) providing a solution of a soluble, interfacially-active polymer having a molecular weight of more than 5 kDa, c) mixing said dispersion of solid core particles with said polymer solution, d) removing free polymer from the obtained mixture; wherein in step a) the solvent is selected from an organic solvent, a mixture of at least two organic solvents or a mixture of at least one organic solvent with water; wherein in step c), the amount of the soluble, interfacially-active polymer mixed with said dispersion of solid core particles exceeds the amount of polymer required to coat the surface of each of the solid core particles with a monolayer of the polymer; wherein step d) is repeated until the requirement described by the following formula is fulfilled:
(STdisp−18 mN/m)/(STsolv−18 mN/m)>0.90,
The present invention relates to a process for producing a particle dispersion comprising the steps of: a) providing a dispersion consisting of a solvent and solid core particles, b) providing a solution of a soluble, interfacially-active polymer having a molecular weight of more than 5 kDa, c) mixing said dispersion of solid core particles with said polymer solution, d) removing free polymer from the obtained mixture; wherein in step a) the solvent is selected from an organic solvent, a mixture of at least two organic solvents or a mixture of at least one organic solvent with water; wherein in step c), the amount of the soluble, interfacially-active polymer mixed with said dispersion of solid core particles exceeds the amount of polymer required to coat the surface of each of the solid core particles with a monolayer of the polymer; wherein step d) is repeated until the requirement described by the following formula is fulfilled:
(STdisp−18 mN/m)/(STsolv−18 mN/m)>0.90,
with STdisp being the surface tension of the modified particle dispersion in [mN/m] and STsolv being the surface tension of the pure solvent or solvent mixture in [mN/m]; and wherein the solvent or solvent mixture contained in the dispersion of solid core particles is miscible with the solvent or solvent mixture contained in the polymer solution. The present invention also relates to a particle dispersion exhibiting a homogenous drying pattern as well as a film made thereof and the use of the non-aqueous particle dispersion.
A measuring system comprises a stand having a base plate and a vertical column fastened thereto, a stand carriage that is movable along the vertical column and having a counter bearing for placing the object, a runner that is fastened to the stand carriage and is movable relative thereto in a guided manner and has an indenter for penetrating the object, having at least one force generation actuator, at least one motion generation actuator, wherein the indenter is coupled to the stand carriage via the actuators. The measuring system further comprises a metrology frame which is fastened to the counter bearing and is supported laterally on the vertical column, a displacement measuring unit for measuring a displacement of the stand carriage and/or the runner with the indenter. The measuring system comprises a force measuring circuit and a displacement measuring circuit both being are largely configured separately from one another.
An electrode structure for guiding and, for example, for splitting a beam of charged particles, for example an electron beam, along a longitudinal path has multipole electrode arrangements that are spaced apart from one another along the longitudinal path and that have DC voltage electrodes. The electrode arrangements are configured to generate static multipole fields centered around the path in transverse planes oriented perpendicular to the longitudinal path, wherein the field strengths of the static multipole fields in the transverse planes each have a local minimum at the location of the path and increase as the distance from the location of the path increases. Field directions of the static multipole fields vary periodically with a period length along the path so that the particles propagating along the path are subjected to an inhomogeneous alternating electric field due to their intrinsic movement and experience a transverse return force towards the longitudinal path on average over time.
A logic gate device comprising a probe structure having an interface contact, a first logic input for receiving a first light pulse having a first carrier-envelope phase that encodes an input state of the first logic input and a second logic input for receiving a second light pulse having a second carrier-envelope phase that encodes an input state of the second logic input. The probe structure is arranged to be irradiated by the first light pulse to generate a first current component within the probe structure that depends on the first carrier-envelope phase and to be irradiated by the second light pulse to generate a second current component within the probe structure that depends on the second carrier-envelope phase. The interface contact is arranged to output a sum current that comprises the first and second current component, wherein the sum current encodes a logic output state of a logic output.
The invention relates to dendritic cells, the NFκB signaling pathway of which has been manipulated by RNA transfection, to the manufacture thereof and to use thereof.
A61K 31/4409 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
A61K 31/4436 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4725 - Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
C07D 213/73 - Unsubstituted amino or imino radicals
C07D 213/74 - Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 409/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
SUPRAPARTICLE AND ADDITIVE FOR THE OPTICAL INDICATION OF HYDROGEN GAS, METHOD FOR PREPARING THE SUPRAPARTICLE(S) OR THE ADDITIVE, AND USE OF THE SUPRAPARTICLE(S) OR THE ADDITIVE
The present invention relates to a supraparticle for optically indicating hydrogen gas or elemental hydrogen. The supraparticle comprises: - a particle superstructure consisting of nanoparticles; and - substances embedded into the particle superstructure. The nanoparticles are selected from the group consisting of SiO2 nanoparticles, metal oxide nanoparticles, polymer nanoparticles, and mixtures thereof. Furthermore, the substances embedded into the particle superstructure comprise: - at least one catalytically active substance for catalyzing a dissociation of hydrogen; and - at least one redox dye. The present invention additionally relates to an additive for optically indicating hydrogen gas, the additive containing or consisting of a plurality of the supraparticles. The present invention further relates to a method for producing the supraparticle(s) or the additive and to the use of the supraparticle(s) or the additive.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
25.
METHOD FOR MANUFACTURING HIGH-FREQUENCY FUNCTIONAL STRUCTURES
The invention relates to a method of manufacturing technical radio frequency functional structures comprising the steps of providing a base body determining the shape of the functional structure and applying an electrically conductive layer to the shape-determining base body by means of wetting the base body with a dispersion containing microparticles and/or nanoparticles.
H01P 11/00 - Apparatus or processes specially adapted for manufacturing waveguides or resonators, lines, or other devices of the waveguide type
B05D 1/18 - Processes for applying liquids or other fluent materials performed by dipping
B05D 1/02 - Processes for applying liquids or other fluent materials performed by spraying
B05D 1/26 - Processes for applying liquids or other fluent materials performed by applying the liquid or other fluent material from an outlet device in contact with, or almost in contact with, the surface
B05D 3/02 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by baking
B05D 3/06 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation
The present disclosure relates to an apparatus and a method for providing a plurality of motion vectors related to an image coded in a bitstream, comprising obtaining a set of sample positions within the image, obtaining respective motion vectors associated with the set of sample positions, deriving an additional motion vector based on information coded in the bitstream, determining an additional sample position located within a triangle, which is formed by three sample positions of the set of sample positions, based on the respective motion vectors associated with the three sample positions, the triangle not including any other sample position of the set, adding the additional sample position to the set of sample positions, and associating the derived additional motion vector with the additional sample position. Such method and apparatus provide for an efficient motion flow compression and reconstruction enabling to recover some sample positions without signaling them in the bitstream.
The present invention relates to a compound for use in a method of treating a pathological condition selected from polycystic kidney disease, polycystic liver disease, and a combination thereof. The present invention further relates to a composition for use in a method of treating a pathological condition selected from polycystic kidney disease, polycystic liver disease, and a combination thereof.
A61K 31/343 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
An electron source (2) for generating an electron beam (8) having a cathode (1) and an anode (4) in the form of a graphene layer (6, 12) epitaxially grown on a silicon carbide substrate (5). The invention is suitable for monolithic preparation of a miniaturized source of a high-energy focused electron beam, including its use as an on-chip X-ray source. All components can be prepared from or on a single silicon carbide chip.
The invention refers to a composite wavelength converter (1) for an LED (100), comprising a substrate (10) and an epitaxial film (20) formed by liquid phase epitaxy on the top and bottom of the substrate (10). Furthermore, the invention refers to a method of preparation of a composite wavelength converter (1) for an LED (100). Furthermore, the invention refers to a white LED light source comprising an LED (100) and an inventive composite wavelength converter (1) mounted on a light emitting surface of the LED (100).
C30B 19/04 - Liquid-phase epitaxial-layer growth using molten solvents, e.g. flux the solvent being a component of the crystal composition
C30B 19/12 - Liquid-phase epitaxial-layer growth characterised by the substrate
C30B 29/28 - Complex oxides with formula A3Me5O12, wherein A is a rare earth metal and Me is Fe, Ga, Sc, Cr, Co or Al, e.g. garnets
C30B 31/04 - Diffusion or doping processes for single crystals or homogeneous polycrystalline material with defined structureApparatus therefor by contacting with diffusion materials in the liquid state
A method for providing transmit symbols to be transmitted by a transmitter to one or more receivers of a wireless MIMO communication system is described. The method includes receiving data to be transmitted to the one or more receivers, and obtaining the transmit symbols to be transmitted by multiplying a data vector including the data to be transmitted by a matrix, like a precoding matrix. The matrix is approximated by a plurality of matrices whose elements are positive or negative integer powers of two so that multiplying the data vector by the matrix includes a series of sub-multiplications, each of the sub-multiplications being realized only by bit shifts and additions.
The present invention relates to a powder for the preparation of three-dimensional objects comprising, or consisting of, supraparticles (8,9,10) comprising at least a first population of first primary particles, wherein the first primary particles are thermoplastic polymeric particles, wherein the first primary particles have a volume-averaged median particle diameter of from 10 to 2000 nm; wherein the primary particles are agglomerated and/or partially sintered together to form the supraparticles, and/or wherein the supraparticles have a volume-averaged median particle diameter of from 2.5 to 100 pm. The invention also relates to a method for preparing in a powder for the preparation of three-dimensional objects comprising a1) providing an at least first population of first primary particles in a first dispersion medium, thereby forming a first dispersion (1); and/or a2) providing an at least second population of second primary particles in a second dispersion medium, thereby forming a second dispersion (2); and/or a3) mixing the first dispersion and the second dispersion, thereby forming a mixture (3) of the first and second dispersion; and b) atomizing (5) the first, second or mixture of the first and second dispersion thereby forming droplets of the first, second or mixture of the first and second dispersion; and c) removing all dispersion media, preferably evaporating all dispersion media by spray drying (7), thereby obtaining supraparticles (8,9,10).
B29C 64/153 - Processes of additive manufacturing using only solid materials using layers of powder being selectively joined, e.g. by selective laser sintering or melting
B22F 1/052 - Metallic powder characterised by the size or surface area of the particles characterised by a mixture of particles of different sizes or by the particle size distribution
B22F 1/10 - Metallic powder containing lubricating or binding agentsMetallic powder containing organic material
The invention relates to a welding electrode for resistance welding, formed by a welding tool made of a metal, the welding tool having a contact surface that comes into contact with the workpiece to be welded. In order to avoid adhesion between the contact surface and a workpiece made, in particular of aluminum, it is suggested in the invention that the contact surface is made of diamond doped with boron.
B23K 11/18 - Resistance weldingSevering by resistance heating taking account of the properties of the material to be welded of non-ferrous metals
B23K 35/22 - Rods, electrodes, materials, or media, for use in soldering, welding, or cutting characterised by the composition or nature of the material
The invention relates to a device for electrolysis comprising a substrate (1, 6) on which an anode formed of a first diamond layer (3) and a cathode formed of a second diamond layer (4) are provided, wherein the first (3) and second diamond layers (4) are each made of diamond doped with boron.
In order to determine a rheological property of a fluid, the fluid is conveyed with a constant volume flow rate through a nozzle and the fluid strand thereby generated is deposited on a substrate. A relative movement takes place between the nozzle and the substrate at a forward feed velocity value. A contour of the liquid strand between the nozzle and the substrate is optically measured, and an extensional viscosity as a rheological property is deduced from knowledge of the volume flow rate, the forward feed velocity value and the contour of the fluid strand.
G01N 11/04 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
G01N 11/08 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by measuring pressure required to produce a known flow
G01N 11/00 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties
35.
Apparatus for determining spatial positions of multiple audio sources
An apparatus determines a spatial position of an audio source in multi moving audio sources scenarios. The apparatus receives audio signal versions as local sound waves. The apparatus determines first and second probabilities for a direction of arrival of the audio signal version based on the audio signal versions received within a first time interval; determines third and fourth probabilities for the direction of arrival of the audio signal version based on the audio signal versions received within a second time interval; determines a first probability difference between the first and third probabilities; determines a second probability difference between the second and fourth probabilities; combines the third probability and the first probability difference to obtain an updated third probability; combines the fourth probability with the second probability difference to obtain an updated fourth probability; and determines the spatial position based on the updated third and fourth probabilities.
H04R 1/40 - Arrangements for obtaining desired frequency or directional characteristics for obtaining desired directional characteristic only by combining a number of identical transducers
G01S 15/46 - Indirect determination of position data
The invention relates to a device and a method for analyzing optoacoustic data, an optoacoustic system for generating and analyzing optoacoustic data and a computer program. The device for analyzing optoacoustic data according to a first aspect of the invention comprises a data processing unit configured to determine a spatial distribution of at least one first value, which relates to concentration of collagen in a tissue comprising at least one of a muscle tissue, connective tissue, organ, tendon and/or pathogenic (fibrotic) tissue, based on optoacoustic data relating to acoustic waves generated in the tissue in response to irradiating the tissue with time-varying electromagnetic radiation at two or more different irradiation wavelengths, derive at least one second value from the spatial distribution of the at least one first value, the at least one second value corresponding to or being derived from at least one distribution parameter characterizing the spatial distribution of the at least one first value within a region of interest of the spatial distribution of the at least one first value, and provide the at least one second value and/or diagnostic information derived from the at least one second value for further use, in particular for displaying the at least one second value and/or diagnostic information on a display unit.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
37.
METHOD OF CLASSIFYING A SAMPLE BASED ON DETERMINATION OF FGFR
The present invention relates to a method of classifying a sample of a patient that suffers from or being at risk of developing urothelial or bladder cancer, said method comprising the steps of: a) determining in said sample from said patient, the presence or absence of alteration in an FGFR gene and/or the expression level of at least one gene encoding for a receptor selected from the group consisting of FGFR1, FGFR2, FGFR3 or FGFR4, and b) classifying the sample of said patient from the outcome of step a) into one of at least two classifications, said classifications comprising good and poor prognosis for treatment with an anti-cancer agent.
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
The present invention relates to a method for determining in a subject's biological sample the relative proportions of papillary renal cell carcinoma (pRCC), clear cell renal cell carcinoma (ccRCC), and chromophobe renal cell carcinoma (chRCC), an array comprising capture molecules capable of specifically binding to RCC signature genes or coding sequences thereof or products encoded thereby, and the use of RCC signature genes for classifying a subject into a renal cell carcinoma (RCC) risk group and/or for determining in a subject's biological sample the relative proportions of pRCC, ccRCC, and chRCC.
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
39.
Audio processing apparatus and method for localizing an audio source
The disclosure relates to an audio processing apparatus for localizing an audio source. The audio processing apparatus comprises a plurality of audio sensors, including a primary audio sensor and at least two secondary audio sensors, configured to detect an audio signal from a target audio source, wherein the primary audio sensor defines at least two pairs of audio sensors with the at least two secondary audio sensors; and processing circuitry configured to: determine for each pair of audio sensors a first set of likelihoods of spatial directions of the target audio source using a first localization scheme; determine a second set of likelihoods of spatial directions of the target audio source using a second localization scheme; and determine a third set of likelihoods of spatial directions of the target audio source on the basis of the first sets of likelihoods and the second set of likelihoods.
H04B 7/08 - Diversity systemsMulti-antenna systems, i.e. transmission or reception using multiple antennas using two or more spaced independent antennas at the receiving station
A method is provided for controlling a technical system using a first agent, where the first agent implements a first artificial neural network. A first input vector of the first neural network and a current state (ht) of the first neural network are converted together into a new state (ht+1) of the first neural network. From the new state (ht+1) of the first neural network a first output vector of the first neural network is generated. A second input vector representing an emotion is then fed to the first agent, with the vector being taken into consideration during the conversion of the neural network into the new state. and a second output vector (e1) representing an expected emotion of the new state (ht+1) of the first neural network is generated.
G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
G06N 3/04 - Architecture, e.g. interconnection topology
41.
WELDING ELECTRODE AND USE OF THE WELDING ELECTRODE
The invention relates to a welding electrode for resistance welding, formed by a welding tool made of a metal, said welding tool having a contact surface (1) that comes into contact with the workpiece (9) to be welded. In order to avoid adhesion between the contact surface (1) and a workpiece made, in particular from aluminium, it is suggested in the invention that the contact surface (1) is made of diamond doped with boron.
A method is provided for controlling a technical system using a first neural network of an agent. A first input vector and a current state (ht) of the first network are converted together into a new state (ht+1) of the first network, from which state a first output vector of the first network is generated. The first output vector of the first network is fed to a second neural network. A first output vector of the second network representing an expected reaction of the second network to the first output vector of the first network, is generated from the new state (wt+1) of the second network. The first output vector of the second network is compared to the first input vector of the first network, in order to train the first network.
The invention relates to a locating method for localizing at least one object using wave-based signals, wherein a wave field emanates from the object to be localized and the wave field emanating from the object is received by a number N of receivers, at least one measurement signal is formed in every receiver, said measurement signal being dependent on the spatial and temporal distribution of the wave field and the phase progression of said measurement signal being characteristically influenced by the signal propagation time from the object to the receiver, wherein, for position locating, phase values for each of the at least two measurement signals are taken as measured phase values, and wherein the current position (P(k)) of the object to be located at the time k is determined by a comparison of at least one linear combination of the measured phase values with at least one linear combination of the associated hypothetical phase values, which result from the transmitter-receiver distance(s), and using a recursive filter/estimator.
G01S 5/16 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations using electromagnetic waves other than radio waves
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
45.
SCD83 FOR WOUND HEALING, HAIR GROWTH, AND SKIN AND HAIR CARE
Provided herein is the use of a soluble form of a member of the CD83 family of proteins (sCD83) for wound healing, including hard-to-heal wounds of elderly-, diabetic-, or patients under immunosuppressant medication. Further provided is the therapeutic use of the sCD83 for the systemic promotion of hair growth, after physical stress/medication, disease and/or depilation by application of systemic sCD83, and cosmetic methods for skin and hair care comprising the topical application of sCD83.
A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
A61P 17/14 - Drugs for dermatological disorders for baldness or alopecia
A61Q 7/00 - Preparations for affecting hair growth
A Computer-implemented method is provided for encrypting data by a server in cooperation with a predetermined number of rate limiters. The method includes receiving, by the server, a user identification, and a password to be encrypted and creating a secret message, the secret message being a key suitable for use with a symmetric key encryption/decryption scheme. The method further includes generating, on the basis of a predetermined interactive cryptographic encryption protocol, a ciphertext which encrypts the user password, and the secret message using secret keys of the rate limiters of the subset, where the threshold is smaller than or equal to the number of rate limiters, and the protocol is adapted such that the server needs only to interact with a subset of the predetermined size of the number of rate limiters for decryption of the ciphertext to recover the secret message.
H04L 29/06 - Communication control; Communication processing characterised by a protocol
H04L 9/06 - Arrangements for secret or secure communicationsNetwork security protocols the encryption apparatus using shift registers or memories for blockwise coding, e.g. D.E.S. systems
The present invention relates to pharmaceutical compositions comprising heterocyclic diamidines and their use in the prophylaxis and/or treatment of diseases associated with fibrosis, in particular for the treatment of diseases such as systemic sclerosis (limited cutaneous scleroderma and diffuse cutaneous scleroderma), pulmonary fibrosis, hepatic cirrhosis, renal fibrosis, chronic graft-versus-host disease, Crohn's disease, arthrofibrosis, myelofibrosis, Dupuytren's disease and nephrogenic systemic fibrosis and tumours selected from mamma carcinoma, endometrial adenocarcinoma, ovarian serous tumor, lung adenocarcinoma, lung squamous cell tumor, colorectal tumor and pancreatic tumor.
An EMI suppression component includes a piezoelectric element that is configured to provide a low impedance propagation path for electromagnetic disturbances at a resonance frequency of the piezoelectric element.
H02M 1/44 - Circuits or arrangements for compensating for electromagnetic interference in converters or inverters
H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
In a method for producing a capacitor, a dielectric structure is generated in a trench of a semiconductor substrate. The dielectric structure includes a plurality of adjacent dielectric layers having opposing material tensions.
H01L 29/92 - Capacitors with potential-jump barrier or surface barrier
H01L 21/78 - Manufacture or treatment of devices consisting of a plurality of solid state components or integrated circuits formed in, or on, a common substrate with subsequent division of the substrate into plural individual devices
H01L 29/94 - Metal-insulator-semiconductors, e.g. MOS
H01L 27/06 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being a semiconductor body including a plurality of individual components in a non-repetitive configuration
Embodiments provide a terminal point of a communication system, wherein a control signal is emitted in the communication system for coordinating the participants of the communication system, wherein the control signal is transferred distributed in correspondence with a frequency hop-based occupancy of resources of the frequency band, indicated by a control signal hopping pattern, wherein the terminal point has a receiver, wherein a receive bandwidth of the receiver is smaller at least by the factor 3 than a bandwidth of the frequency hop-based occupancy of resources of the frequency band, indicated by the control signal hopping pattern, wherein the terminal point is configured to receive a reference signal, the reference signal having information on the control signal, wherein the terminal point is configured to receive the control signal based on the information on the control signal.
Embodiments provide a controller for a participant of a communication system wirelessly communicates in a frequency band used for communication by a plurality of communication systems, wherein the controller is configured to identify a network-specific channel access pattern, wherein the network-specific channel access pattern indicates a frequency hop-based and/or time hop-based occupancy of resources of the frequency band that is usable for the communication of the communication system, wherein the controller is configured to identify a relative channel access pattern, wherein the relative channel access pattern indicates, from the usable frequency hop-based and/or time hop-based occupancy of resources of the network-specific channel access pattern, an occupancy of resources that is to be used for the transfer of data of the participant.
A data receiver configured to receive a signal having at least two partial data packets, the data receiver being configured to estimate a state of a transmission channel, to obtain first channel state information, to demodulate a first set of received symbols from different data packets, to obtain a first set of received encoded bits, wherein the data receiver is configured to decode the first set of received encoded bits to determine, a first set of estimated encoded bits which corresponds more likely to a first set of transmitted encoded bits than the received encoded bits, and to map the first set of estimated bits to estimated transmission symbols using a mapping rule matching a transmitter-side mapping rule to obtain a first set of estimated transmission symbols, and to determine second channel state information using the first set of estimated transmission symbols.
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
C07C 275/26 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07C 275/24 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
C07D 207/452 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
C07D 233/16 - Radicals substituted by nitrogen atoms
C07D 409/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 333/20 - Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
C07D 295/125 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
C07D 333/58 - Radicals substituted by nitrogen atoms
Aspects of the present disclosure include conformationally restricted analogs of catecholamine type compounds (e.g., isoprenaline, adrenaline, noradrenaline) which activate β2AR with high selectivity over β1AR. The subject beta-2 selective adrenergic receptor agonist compounds may serve as bronchiodilators and find use in the treatment of a variety of bronchoconstrictive diseases and conditions. Also provided are compositions and methods for treating preterm labor. A method of treating acute asthma including administration of a subject compound to a subject in need thereof is provided. The subject method can provide for reduced undesirable side effects associated with non-selective β-adrenergic receptor agonism, such as inotropic and chronotropic effects that leads to elevated blood pressure. The compounds can also be used to prevent or treat heart failure. Kits and compositions for practicing the subject methods are also provided.
A transmitter is configured to transmit at least one signal with a pilot sequence having a plurality of pilot symbols, wherein the transmitter has a signal generator, wherein the signal generator provides the pilot sequence, wherein the signal generator provides the pilot sequence such that the pilot sequence has at least two symbol groups each having at least two pilot symbols, and the symbol groups, when evaluating a signal received by a receiver as a result of the transmission of the signal with respect to a phase, the symbol groups generate phase errors that depend on a temporal off-set between a reference point in time of the transmission of the signal by the transmitter and a value assumed and/or estimated for the evaluation for the reference point in time, said phase errors essentially mutually compensating each other across the symbol groups in the evaluation.
The present invention relates to a method for manufacturing an electronic or electrical system, the method comprising the layer-free production of at least one physical structure (101, 102) which is designed to guide electromagnetic waves, using at least one additively operating apparatus, wherein the layer-free production of the spatial, layer-free structure comprises the simultaneous or sequential application and/or removal of one or more materials in the spatial arrangement, as a result of which the electronic or electrical system is partially or completely formed. The invention further relates to a system which is manufactured in accordance with the method.
B29C 70/88 - Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts characterised primarily by possessing specific properties, e.g. electrically conductive or locally reinforced
B29C 64/112 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
H05K 3/12 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern using printing techniques to apply the conductive material
57.
METHODS FOR SCREENING AND IDENTIFYING AGENTS THAT INHIBIT OR MODULATE THE NUCLEAR EGRESS COMPLEX OF HERPESVIRUSES
The present invention generally provides for a novel NEC-targeted strategy for the development of antiherpesviral drugs as well as for a novel antiviral strategy targeting the viral-cellular nuclear egress complex (NEC) for a small molecule-based therapy or prophylaxis to control infections with human cytomegalovirus or other pathogenic viruses of the group of the Herpesviridae. Methods for screening agents / compounds /small molecules modulating/ inhibiting the nuclear egress complex of Herpesviridae are provided as well. Specifically novel drug targets of the viral nuclear egress complex of viruses of the Herpesviridae are provided.
Embodiments relate to a controller for a participant of a communications system, wherein the communications system communicates wirelessly in a frequency band which is used for communication by a plurality of communications systems, wherein the controller is designed to determine a network-specific channel access pattern, wherein the network-specific channel access pattern specifies a frequency- and/or time-hop-based allocation of resources of the frequency band which can be used for the communication of the communications system, wherein the controller is designed to determine a relative channel access pattern, wherein the relative channel access pattern specifies an allocation of resources, to be used for a transmission of data of the participant, from the usable frequency- and/or time-hop-based allocation of resources of the network-specific channel access pattern.
Embodiments relate to a controller for a participant of a communications system, wherein the communications system wirelessly communicates in a frequency band which is used by a plurality of communications systems for communication, wherein the controller is designed to determine a channel access pattern, wherein the channel access pattern specifies a frequency- and/or time-hop-based allocation of the frequency band which can be used for the communication of the communications system, wherein the controller is designed to determine the channel access pattern according to individual information of the communications system and according to a status of a number sequence generator for generating a number sequence or a number of a number sequence.
The present invention relates to a nucleic acid molecule encoding a chain myeloid capable of specifically binding to CD33, CD16 and CD123, wherein said nucleic molecule comprises: (a) a nucleic add molecule encoding a protein represented by SEQ ID NO:1; (b) a nucleic acid molecule represented by SEQ ID NO:2; (c) the nucleic add molecule of (b), wherein each thymine is replaced by urea; (d) a nucleic acid molecule encoding a protein having at least 98% sequence identity to the protein of (a); or (e) a nucleic add molecule that is degenerate with respect to the nucleic acid molecule of (b) or (c). The present invention further relates to a vector comprising the nucleic acid molecule of the invention, a host cell transformed or transfected with the nucleic acid molecule or the vector of the invention, as well as to a method for the production of a single chain myeloid capable of specifically binding to CD33, CD16 and CD123. Furthermore, the present invention also relates to a single chain myeloid capable of specifically binding to CD33, CD16 and CD123 encoded by the nucleic acid molecule of the invention, as well as to a composition comprising the nucleic acid molecule, the vector, the host cell and/or the single chain myeloid of the invention. Also, encompassed by the present invention are the nucleic acid molecule, the vector, the single chain myeloid and/or the composition of the invention for use in the treatment of acute myeloid leukaemia and/or myelodysplastic syndrome, as well as a method of treating acute myeloid leukaemia and/or myelodysplastic syndrome.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
61.
Apparatus and method for calibrating measuring instruments
A method and apparatus is provided for implementing a parametric down-conversion (PDC)-based calibration comprising calibrating a measuring instrument; disposing a pinhole at a position of a light-emitting sample for which the measuring instrument needs to be calibrated; irradiating a nonlinear crystal with a light source; setting the nonlinear crystal by ensuring a phase-matching wavelength of the nonlinear crystal is set at one boundary of a desired bandwidth; acquiring one or more PDC spectrums by the measuring instrument; obtaining peak values and their corresponding wavelengths from each acquired spectrum; and obtaining a response function based on the peak values and corresponding wavelengths.
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
Embodiments represent a data receiver, wherein the data receiver is designed for receiving a signal, wherein the signal has at least two separate sub-data-packets, wherein the at least two separate sub-data-packets have symbols mapping coded bits resulting from a coding of a data bit string carried out for the at least two separate sub-data-packets together and introducing a redundancy, wherein the data receiver is designed to estimate a channel status of a transmission channel of the signal based on the received signal, in order to obtain first channel status information, wherein the data receiver is designed to demodulate a first set of received symbols from different sub-data-packets using the first channel status information, wherein the first set of received symbols is an actual partial quantity of the received symbols of the at least two sub-data-packets in order to obtain a first set of received coded bits, wherein the first set of received coded bits permits an inference of a first set of coded bits corresponding to the first set of received coded bits on the transmission side, with the utilisation of the transmission-side redundancy-generating coding, wherein the data receiver is designed to decode the first set of received coded bits, to determine a first set of estimated coded bits, with the utilisation of the transmission-side redundancy-generating coding, which corresponds to a first set of transmitted coded bits with a higher level of probability than the received coded bits, and to map the first set of estimated bits as estimated transmission symbols using a mapping rule corresponding to a transmission-side mapping rule in order to obtain a first set of estimated transmission symbols, wherein the data receiver is designed to determine second channel status information using the first set of estimated transmission symbols.
Embodiments provide a transfer method for wirelessly transferring data in a communication system (e.g. a sensor network or telemetry system). The data includes core data and extension data, wherein the core data is encoded and distributed in an interleaved manner to a plurality of core sub-data packets, wherein the extension data is encoded and distributed in an interleaved manner to a plurality of extension sub-data packets, wherein at least a part of the core data contained in the core sub-data packets is needed for receiving the extension data or extension data packets.
H04B 1/7143 - Arrangements for generation of hop patterns
H04L 1/00 - Arrangements for detecting or preventing errors in the information received
H03M 13/27 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes using interleaving techniques
H03M 13/37 - Decoding methods or techniques, not specific to the particular type of coding provided for in groups
H03M 13/33 - Synchronisation based on error coding or decoding
64.
Variable sub-packet lengths for telegram splitting in networks with low power consumption
Embodiments provide a transfer method for transferring data of variable length using a fixedly specified number of sub-data packets to which the data of variable length is distributed.
A particulate material and a process for the production thereof are provided, which particulate material comprises zeolitic particles having a crystalline structure, which contain as the main component a zeolite material having a zeolitic framework structure formed from Si, O and optionally Al, and/or a zeolite-like material having a zeolitic framework structure which is formed not only from Si, O and optionally Al, wherein the zeolitic particles are in the form of essentially spherical particles with nanometer dimensions.
C01B 39/40 - Type ZSM-5 using at least one organic template directing agent
B01J 29/03 - Catalysts comprising molecular sieves not having base-exchange properties
C01B 39/04 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereofDirect preparation thereofPreparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactantsAfter-treatment thereof using at least one organic template directing agent, e.g. an ionic quaternary ammonium compound or an aminated compound
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
B01J 20/30 - Processes for preparing, regenerating or reactivating
C07C 275/26 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07C 275/24 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
C07D 207/452 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
C07D 233/16 - Radicals substituted by nitrogen atoms
C07D 409/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 333/20 - Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
C07D 295/125 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
C07D 333/58 - Radicals substituted by nitrogen atoms
A data transmitter is provided, having: a generator for generating transmission data packets, configured to split a first data packet into at least three transmission data packets, each of the transmission packets being shorter than the first data packet, the generator being configured to channel-encode the at least three transmission packets such that only a portion thereof is required for decoding the first data packet; a transmission element for transmitting data packets, configured to transmit the at least three transmission packets in a frequency channel via a communications channel with a time gap; a monitor element for monitoring the frequency channel, configured to recognize an interference or transmission of a further data transmitter in the frequency channel; the transmission element being configured not to transmit via the communications channel a packet, waiting for transmission, of the at least three transmission packets if an interference or transmission from a further data transmitter is recognized by the monitor element at the time of transmitting the transmission data packet.
What is described is an Radio Frequency Identification (RFID) tag configured for communicating with an Radio Frequency Identification (RFID) reader, wherein the RFID tag is configured to receive a query command from the RFID reader, to measure a duration of a TRcal signal comprised by the query command, and to determine an individual Backscatter Link Frequency for communicating with the RFID reader based on the measured duration of the TRcal signal. The invention also refers to an RFID reader and to a corresponding method.
G06K 19/077 - Constructional details, e.g. mounting of circuits in the carrier
G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation
69.
Method and apparatus for the detection of bacteria
The present invention relates to a fast, simple and very sensitive method for the detection of bacteria, comprising the steps of providing one or more suspensions each comprising at least one species of labeled test bacteriophages which specifically bind to a bacterial species to be detected; adding a sample to be tested for the presence of at least one bacterial species to be detected to the one or more suspensions; filtering the reaction mixture; detecting bacteria-bacteriophages-complexes on the surface of the filter in the retentate, provided that at least one bacterial species to be detected is present, wherein the complexes consist of bacteria of the at least one bacterial species to be detected and test bacteriophages of the at least one species of test bacteriophages bound thereto; detecting unbound test bacteriophages in the filtrate; processor-aided processing of received detection signals and output of detection results.
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
70.
TRANSMITTER AND RECEIVER AND CORRESPONDING METHODS
The invention relates to a transmitter (1) which is configured in such a way that it transmits signals having a respective pilot sequence with multiple pilot sequence symbols, wherein the transmitter (1) has a signal generator (2), wherein the signal generator (2) is configured in such a way that it provides the pilot sequence based on a basic sequence having multiple basic sequence symbols, wherein the signal generator (2) provides the pilot sequence symbols based on the basic sequence symbol that is successively repeated (R-1) times, and wherein R is a natural number greater than or equal to two, wherein the basic sequence is configured in such a way that a correlation of the pilot sequence with a transmission signal formed by the pilot sequence has a primary maximum that is as narrow as possible and/or secondary maximums that are as small as possible.
The invention relates to a transmitter (1) which is configured in such a way that it transmits at least one signal having a pilot sequence with multiple pilot symbols, wherein the transmitter (1) has a signal generator (2), wherein the signal generator (2) provides the pilot sequence, wherein the signal generator (2) provides the pilot sequence in such a way that the pilot sequence has at least two symbol groups with a respective at least two pilot symbols, and wherein, with an evaluation of a signal received by a receiver (10) after the transmission of the signal, in relation to a phase of a time offset between a reference time of the transmission of the signal by the transmitter (1) and a value that is assumed and/or estimated for the reference time for the evaluation, the symbol groups generate corresponding phase errors, which, during the evaluation, together substantially offset one another across the symbol groups.
The present invention is directed to compounds, tautomers, stereoisomers, and chemically modified compounds thereof, and their use in preventing and/or treating tumors of metastasis and/or cartilage defect, and to a pharmaceutical composition comprising such compound.
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A61P 35/04 - Antineoplastic agents specific for metastasis
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
A61K 31/505 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim
A61K 31/513 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
A61K 31/53 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
A61K 31/435 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
A61K 31/4985 - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K 31/4025 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
A61K 31/4152 - 1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
A61K 31/4402 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
A61K 31/4453 - Non-condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
73.
A CD33-, CD16- AND CD123-SPECIFIC SINGLE CHAIN TRIPLEBODY
The present invention relates to a nucleic acid molecule encoding a single chain triplebody capable of specifically binding to CD33, CD16 and CD123, wherein said nucleic acid molecule comprises: (a) a nucleic acid molecule encoding a protein represented by SEQ ID NO:1; (b) a nucleic acid molecule represented by SEQ ID NO:2; (c) the nucleic acid molecule of (b), wherein each thymine is replaced by uracil; (d) a nucleic acid molecule encoding a protein having at least 98% sequence identity to the protein of (a); or (e) a nucleic acid molecule that is degenerate with respect to the nucleic acid molecule of (b) or (c). The present invention further relates to a vector comprising the nucleic acid molecule of the invention, a host cell transformed or transfected with the nucleic acid molecule or the vector of the invention, as well as to a method for the production of a single chain triplebody capable of specifically binding to CD33, CD16 and CD123. Furthermore, the present invention also relates to a single chain triplebody capable of specifically binding to CD33, CD16 and CD123 encoded by the nucleic acid molecule of the invention, as well as to a composition comprising the nucleic acid molecule, the vector, the host cell and/or the single chain triplebody of the invention. Also encompassed by the present invention are the nucleic acid molecule, the vector, the single chain triplebody and/or the composition of the invention for use in the treatment of acute myeloid leukaemia and/or myelodysplastic syndrome, as well as a method of treating acute myeloid leukaemia and/or myelodysplastic syndrome.
A61P 35/02 - Antineoplastic agents specific for leukemia
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Exemplary embodiments provide a transmission method for transmitting data of variable length using a fixedly predefined number of data sub-packets, into which the data of variable length is split.
Exemplary embodiments provide a transmission method for the wireless transmission of data in a communications system (e.g. a sensor network or telemetry system). The method comprises the step of transmitting the data using at least two time hopping patterns and/or frequency hopping patterns, wherein a second pattern of the at least two patterns is a time- and/or frequency-shifted version of a first pattern of the at least two patterns.
Exemplary embodiments provide a transmission method for the wireless transmission of data in a communications system (e.g. a sensor network or telemetry system). The data comprises core data and additional data, the core data being split in encoded and interleaved form into a plurality of core data sub-packets and the additional data being split in encoded and interleaved form into a plurality of additional data sub-packets, wherein at least some of the core data contained in the core data sub-packets is required for the receipt of the additional data or additional data packets.
H03M 13/27 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes using interleaving techniques
H04L 1/00 - Arrangements for detecting or preventing errors in the information received
77.
APPARATUS AND METHOD FOR CALIBRATING MEASURING INSTRUMENTS
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (Germany)
Inventor
Manceau, Mathieu
Boyd, Robert W.
Leuchs, Gerd
Chekhova, Maria V.
Lemieux, Samuel
Abstract
A method and apparatus is provided for implementing a parametric down-conversion (PDC)-based calibration comprising calibrating a measuring instrument; disposing a pinhole at a position of a light-emitting sample for which the measuring instrument needs to be calibrated; irradiating a nonlinear crystal with a light source; setting the nonlinear crystal by ensuring a phase-matching wavelength of the nonlinear crystal is set at one boundary of a desired bandwidth; acquiring one or more PDC spectrums by the measuring instrument; obtaining peak values and their corresponding wavelengths from each acquired spectrum; and obtaining a response function based on the peak values and corresponding wavelengths.
Embodiments relate to a data receiver with a device for receiving sub-data packets, a device for ascertaining a phase difference, and a device for ascertaining a distance difference. The device for receiving sub-data packets is designed to receive at least two sub-data packets from a data transmitter and to combine the at least two sub-data packets in order to obtain a data packet which is transmitted in a divided state into the at least two sub-data packets by the data transmitter. Each of the at least two sub-data packets is shorter than the data packet. The device for receiving sub-data packets is designed to receive the at least two sub-data packets on at least two different carrier frequencies. The device for ascertaining a phase difference is designed to ascertain a phase difference between the at least two sub-data packets, said phase difference being caused by the at least two different carrier frequencies and the path delay. The device for ascertaining a distance difference between the data receiver and the data transmitter is designed to ascertain the distance difference on the basis of the ascertained phase difference between the at least two sub-data packets.
G01S 13/84 - Systems using reradiation of radio waves, e.g. secondary radar systemsAnalogous systems wherein continuous-type signals are transmitted for distance determination by phase measurement
G01S 17/08 - Systems determining position data of a target for measuring distance only
H04W 64/00 - Locating users or terminals for network management purposes, e.g. mobility management
A topologically-protected traveling-wave amplifier includes resonators arranged in a two-dimensional array defining a periphery including a first edge. An output line is coupled to an output resonator disposed along the first edge spaced from an input resonator coupled to an output line. A synthetic gauge field generator associated with the resonators provides a topologically-protected edge state corresponding to propagation along the periphery in a propagation direction from the input resonator along the first edge to the output resonator. A parametric driving element creates pairs of photons in the edge state and amplifies a signal propagating along the first edge in the propagation direction. A signal incident from the input line propagates in the propagation direction along the first edge while being amplified and is detected at the output line as an amplified signal. A signal incident from the output line is attenuated before emerging at the input resonator.
The invention relates to a circulatory assistance device (22) for a heart of a living being, comprising a cuff for periodically applying pressure to the heart (10) by means of at least one dielectric elastomer membrane which, by means of a control device (30), can be controlled in synchronization with a cardiac beat in order to convey blood in pulses, wherein the cuff is designed to be pulled over the outside of the heart (10) and for this purpose has an inner shape that is adapted to the outer contour of the heart (10) at least in the region outside the ventricles, wherein the cuff is composed of an outer contraction layer (24) and an inner padding layer (26) which is filled with an incompressible liquid and has at least one outlet valve (28) which is closed in a normal state and opened in an emergency state.
A61M 60/148 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
A61M 60/268 - Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
A61M 60/424 - Details relating to driving for positive displacement blood pumps
81.
DIAGNOSIS, TREATMENT AND PREVENTION OF NEUROTENSIN RECEPTOR-RELATED CONDITIONS
The present invention describes a compound of formula (I) which can be used in the diagnosis, treatment or prevention of neurotensin receptor-related conditions such as tumors and hematological malignancies.
C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
C07F 5/00 - Compounds containing elements of Groups 3 or 13 of the Periodic Table
82.
Apparatus and method for driving an array of loudspeakers
A local wave field synthesis apparatus, which includes a determination module for determining desired sound pressures and desired particle velocity vectors at a plurality of control points, a computation module for computing sound pressures and particle velocity vectors at the plurality of control points based on a set of filter parameters, an optimization module for computing an optimum set of filter parameters by jointly optimizing computed sound pressures towards the desired sound pressures and computed particle velocity vectors towards the desired particle velocity vectors, and a generator module for generating the drive signals based on the optimum set of filter parameters, wherein the plurality of control points are located on one or more contours around the one or more audio zones.
Embodiments provide a receiver comprising a receiving unit and a synchronization unit. The receiving unit is configured to receive a data packet comprising a pilot sequence. The synchronization unit is configured to separately correlate the pilot sequence with at least two partial reference sequences corresponding to a reference sequence for the pilot sequence of the data packet, in order to obtain a partial correlation result for each of the at least two partial reference sequences, wherein the synchronization unit is configured to non-coherently add the partial correlation results in order to obtain a coarse correlation result for the data packet.
A data transmitter generates transmission data packets, configured to split a first data packet into at least three transmission data packets that are each shorter than the first data packet. The transmission data packets are channel-encoded such that only a portion of the transmission data packets is required for decoding the first data packet. Means for transmitting data packets transmits the data packets in a frequency channel via a communications channel with a time gap, and means for monitoring the frequency channel recognizes an interference or transmission of a further data transmitter in the frequency channel. The means for transmitting is configured not to transmit, transmit only partly or at a later time via the communications channel a transmission data packet, waiting for transmission, if an interference or transmission from a further data transmitter is recognized by the means for monitoring at the time of transmitting the transmission data packet.
Embodiments provide a transmitter, configured to operate in a mobile communication system according to a mobile communication standard (e.g., 3GPP), wherein resources of the communication system are divided into resources elements. The transmitter is configured to transmit an additional telegram by separating the telegram into a plurality of data packets, each of the data packets being shorter than the telegram, and transmitting each of the data packets respectively in one of the resource elements.
The invention relates to a zeolitic material comprising zeolitic monocrystals, each of which has a pore system encompassing at least one micropore system and at least one macropore system, and to a method for producing a zeolitic material of said type. In said method, porous oxide particles are converted into the zeolitic material in the presence of an organic template and steam.
C01B 39/40 - Type ZSM-5 using at least one organic template directing agent
C01B 39/48 - Other types characterised by their X-ray diffraction pattern and their defined composition using at least one organic template directing agent
B01J 29/40 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereof of the pentasil type, e.g. types ZSM-5, ZSM-8 or ZSM-11
C01B 37/02 - Crystalline silica-polymorphs, e.g. silicalites
C01B 39/04 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereofDirect preparation thereofPreparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactantsAfter-treatment thereof using at least one organic template directing agent, e.g. an ionic quaternary ammonium compound or an aminated compound
C01B 39/08 - Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements the aluminium atoms being wholly replaced
C01B 39/12 - Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements the replacing atoms being boron atoms
C01B 39/54 - Phosphates, e.g. APO or SAPO compounds
C30B 7/10 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions by application of pressure, e.g. hydrothermal processes
An RFID reader includes a transmitter, a receiver, and an evaluator. The receiver receives signals from RFID tags within a given number of slots of a time frame with a given frame size and provides a number of successful slots and a number of collided slots. The evaluator sets a modified frame size based on an estimated number of RFID tags which is determined based on the frame size, the number of successful slots, and the number of collided slots. The invention also refers to a corresponding method.
G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation
H04B 7/00 - Radio transmission systems, i.e. using radiation field
H04Q 5/22 - Selecting arrangements wherein two or more subscriber stations are connected by the same line to the exchange with indirect connection, i.e. through subordinate switching centre the subordinate centre not permitting interconnection of subscribers connected thereto
88.
Method and apparatus for motion correction and image enhancement for optical coherence tomography
Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for correction of such distortions and data gaps are described herein. Motion-corrected data is arrived at by applying three-dimensional transforms to input three-dimensional data sets that represent at least partially overlapping regions of the imaged object. The three dimensional transforms are computed based on an objective function that accounts for similarity between the transformed three-dimensional data sets and the estimated motion of the object relative to an imaging instrument. Methods and systems described herein advantageously eliminate the need for postulated assumptions and reliance on landmarks and are capable of filling data gaps, thereby producing high quality, undistorted images of objects subject to movement during imaging. Multiple motion-corrected data sets can be merged or combined to produce a data set with improved image quality.
The invention relates to an electron beam splitter (1) comprising a multi-pole electrode arrangement with a high-frequency alternating current voltage (5), which extends along a specified path (6) from an inlet side (9) to an outlet side (10), wherein the electrode arrangement (5) generates on the inlet side (9) with a first number of electrodes (7) impacted by the voltage a first oscillating electric field (61), which forms on a transversal plane a single local confinement minimum (62) in a time-averaged manner, and wherein the electrode arrangement (5) generates at least on the outlet side (10) with a second number of voltage-impacted electrodes (7) a second oscillating electric field (65), which forms at least two local confinement minimums (66, 67) in a time averaged manner.
The invention relates to methods for the intra-amniotic administration of EDA agonists, in particular EDI200. Use of the methods described allow for the design of targeted therapeutic dosing and administration regimens in order to correct or alter abnormal phenotypes associated with ectodermal dysplasias, in particular, XLHED.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
In a method for producing a capacitor, a dielectric structure is generated in a trench of a semiconductor substrate. The dielectric structure includes a plurality of adjacent dielectric layers having opposing material tensions.
H01L 21/283 - Deposition of conductive or insulating materials for electrodes
H01L 21/78 - Manufacture or treatment of devices consisting of a plurality of solid state components or integrated circuits formed in, or on, a common substrate with subsequent division of the substrate into plural individual devices
H01L 29/94 - Metal-insulator-semiconductors, e.g. MOS
H01L 27/06 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being a semiconductor body including a plurality of individual components in a non-repetitive configuration
92.
Method and device for joining a plurality of individual digital images to form a total image
In a device and a corresponding method for joining a plurality of individual digital images to form a total image, a plurality of features is determined in a first individual image by means of a selection unit using a feature-based algorithm and then tracked in a second individual image by means of a tracking unit. A transformation matrix, with which the individual images are joined in an output unit to form the total image, is calculated from the determined feature correspondences in a transformation unit. The individual images can be joined in real time and with a high degree of accuracy by means of the feature-based algorithm in combination with a robust algorithm to calculate the transformation matrix.
The present invention relates to a method for in vitro detection and/or monitoring of a disease in a sample, based on measurement of enzymatic activity of proteases activated and secreted upon disease development, to modified peptides used for the enzymatic detection of the proteases, the use of the peptides, a kit comprising such peptides and the use of ADAM-protease activity as a surrogate marker for disease burden and activity in infectious, inflammatory, and malignant diseases, such as HIV infection and melanoma.
C12Q 1/37 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving peptidase or proteinase
G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
G01N 33/542 - ImmunoassayBiospecific binding assayMaterials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
94.
Method and apparatus for spatially resolved diagnosis
A method and device for diagnosing an electrical condition of a spatially extended hardware component in a spatially resolved manner via interference between pulses fed into the component by a signal generator. The method includes: feeding at least two pulses into the component offset by a pulse interval; detecting the interfered pulses and echoes via an analysis unit; varying the pulse interval for the spatially resolved scanning of the hardware component along its length; repeating the steps until the component has been scanned at least in some sections; and analyzing the detected interfered pulses in the analysis unit. The device includes at least one signal generator connected to the component and to an analysis unit to generate the pulses, wherein local energy losses are mathematically determined over the length of the component on the basis of a plurality of interference voltage waveforms and voltage waveforms induced by the pulses.
G01R 31/00 - Arrangements for testing electric propertiesArrangements for locating electric faultsArrangements for electrical testing characterised by what is being tested not provided for elsewhere
G01R 31/02 - Testing of electric apparatus, lines, or components for short-circuits, discontinuities, leakage, or incorrect line connection
G01R 31/11 - Locating faults in cables, transmission lines, or networks using pulse-reflection methods
G01R 31/08 - Locating faults in cables, transmission lines, or networks
The invention relates to a filter material which is used, in particular in filters or as a filter for treating and/or purifying gas, in particular for clean room environments. The filter material comprises at least one activated carbon, in particular with reactive and/or catalytic finishing and the activated carbon is present in the form of discrete activated carbon particles, preferably in a spherical and/or grain form. The activated carbon comprises and/or is provided with at least one metal component which contains at least one metal-containing ionic liquid (IL), containing in particular metal ions, preferably based on a metal compound.
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
B01D 53/04 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
96.
METHOD FOR IN VITRO DETECTION AND MONITORING OF A DISEASE BY MEASURING DISEASE-ASSOCIATED PROTEASE ACTIVITY IN EXTRACELLULAR VESICLES
The present invention relates to a method for in vitro detection and/or monitoring of a disease in a sample, based on measurement of enzymatic activity of proteases activated and secreted upon disease development, to modified peptides used for the enzymatic detection of the proteases, the use of the peptides, a kit comprising such peptides and the use of ADAM-protease activity as a surrogate marker for disease burden and activity in infectious, inflammatory, and malignant diseases, such as HIV infection and melanoma.
C12Q 1/37 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving peptidase or proteinase
G01N 33/542 - ImmunoassayBiospecific binding assayMaterials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
The invention relates to dendritic cells, the NFκB signaling pathway of which has been manipulated by RNA transfection, to the manufacture thereof and to use thereof.
The invention relates to a tool for an ultrasonic welding device, wherein a contact face of a carrier body (1) produced from a metal facing a component to be welded is provided with a diamond coating (3). To improve the durability, it is proposed in accordance with the invention for the diamond coating to be produced by means of CVD methods and to have a thickness (D2) in the range from 0.5 to 20 μm.
In a device and a corresponding method for joining a plurality of individual digital images to form a total image, a plurality of features is determined in a first individual image by means of a selection unit using a feature-based algorithm and then tracked in a second individual image by means of a tracking unit. A transformation matrix, with which the individual images are joined in an output unit to form the total image, is calculated from the determined feature correspondences in a transformation unit. The individual images can be joined in real time and with a high degree of accuracy by means of the feature-based algorithm in combination with a robust algorithm to calculate the transformation matrix.
The present invention concerns a method and a device for determining mechanical stress load, and optionally interface effects, on particles dispersed in a fluid. According to the invention, fluid comprising dispersed particles such as biomolecules is fed into a sample space of a device comprising a jacket which encloses a sample chamber and at least two rolls arranged within said jacket such that said sample space is defined between said rolls, said rolls being independently rotatable with respect to each other, wherein said jacket has an inner surface which is essentially adapted to the outer surface of the rolls, rotational movement is imparted to at least one of the rolls of said device, and changes in the state of said particles are determined from which mechanical stress load acting on the particles can be determined.
patents
