Embodiments disclosed herein provide a compression system including a squeeze plate, a linkage assembly, and a drive assembly. The squeeze plate is configured to engage with a fluid bag. The linkage assembly comprises a plurality of brackets each coupled to a plurality of linkage sets, where actuation of the linkage assembly causes lateral translation of the squeeze plate. The drive assembly comprises a lead screw disposed through each of the plurality of brackets, an actuator configured to rotate the lead screw to actuate the drive assembly, and a nut assembly coupled to the lead screw and at least one of the plurality of brackets, where the nut assembly is configured to provide a biasing force to maintain a target range of pressure on the fluid bag if the actuator fails.
Certain embodiments disclosed herein provide a surgical cassette including a housing, one or more retaining rings coupled to the housing, and one or more valve assemblies coupled to the housing by the one or more retaining rings. The one or more valve assemblies configured to control fluid communication between one or more channels within the housing. Each valve assembly includes a valve body having a first end with a first shoulder, a second end with a second shoulder, a cylindrical surface connecting the first shoulder and second shoulder, and an upper valve elastomer. The upper valve elastomer includes a first side configured to engage with the first shoulder of the valve body and a second side configured to engage with the retaining ring to facilitate a fluidic seal at a base of the housing.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
Some embodiments provide a surgical cassette designed for use in ophthalmic surgical procedures, which features a multiple chamber pump elastomer to seal multiple chambers within the device. The elastomer is comprised of a silicone rubber component that incorporates a plurality of grooves on its top face and seal beads on its lower portion. The grooves enable lateral deformation of the silicone rubber under compression, improving the seal of the multiple chambers and reducing or eliminating leak paths, thus enhancing the device's performance. The seal beads, strategically placed on the lower portion of the silicone rubber component, prevent separation and lifting of the pump elastomer at the corners by conforming to the geometry of the corners.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
4.
PRESSURE SENSORS FOR OPHTHALMIC SURGICAL CONSOLES AND CASSETTES
A sensor assembly for sensing fluid pressure in a surgical cassette is provided. The sensor assembly includes a tubing having a first portion and a second portion, a follower assembly operable to engage with a retaining ring of the surgical cassette coupled to the first portion, a collar on the second portion of the tubing operable to fit into a bearing of a pump head of a fluid pump assembly within a surgical console operable to receive the surgical cassette, and a biasing element between the follower assembly and the collar operable to apply a biasing force to the follower assembly to engage the follower with the surgical cassette. The follower assembly includes a follower coupled to a cup and a sensor component.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
An apparatus for delivering an implant to an eye using a push rod and hydraulic fluid flow or pressure. An implant may be stored, advanced, and delivered to an eye using hydraulic fluid, which can be stored in the apparatus or a sterile container and delivered through the push rod. The plunger may rigidly advance the implant to a sealed position in a first phase, and then the implant may be advanced into the eye via hydraulic pressure or fluid flow in a second phase.
A surgical system including battery packs, a power subsystem and a controller is provided. The power subsystem is configured to connect at least two battery packs in parallel during a backup mode, disconnect the battery packs in a non-backup mode, and prevent each battery pack from charging one or more other battery packs during parallel operation. The controller is configured to individually charge each battery pack to a power capacity equal to or less than a predetermined power capacity, such as 100 Wh.
H02J 9/06 - Circuit arrangements for emergency or stand-by power supply, e.g. for emergency lighting in which the distribution system is disconnected from the normal source and connected to a standby source with automatic change-over
A61B 17/00 - Surgical instruments, devices or methods
H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
The present disclosure generally relates to fluid control valves for delivering and/or aspirating fluid during ophthalmic surgeries and procedures. In one embodiment, a valve assembly includes a first portion configured to fluidly couple with a gas supply line and a second portion configured to fluidly couple with a liquid supply line and an infusion line via two or more through channels. The first portion and the second portion are partitioned or separated from each other by a filter having a hydrophobic membrane configured to prevent the flow of liquids therethrough while allowing the free flow of gas. Accordingly, an infusion liquid may flow through the second portion while gases may be simultaneously aspirated through the first portion, without any liquids travelling into the gas supply line. The gas supply line may thus be utilized to vent or purge gases from the infusion line before or during performance of surgical procedures.
A video overlay device for use in surgical settings to overlay surgical parameters from a surgical console over images from a surgical microscope is provided. The device includes a video input port configured to receive image data from a camera and a data port configured to receive a removable storage device storing encrypted WiFi configuration data. The device further includes a WiFi transceiver configured to connect, based on the encrypted WiFi configuration data, to a local WiFi network hosted by a surgical console and receive, from the surgical console, overlay data. The device further includes a processor, configured to generate, based on the image data and the overlay data, combined image data and a video output port configured to send the combined image data to a display.
H04N 5/272 - Means for inserting a foreground image in a background image, i.e. inlay, outlay
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
H04N 7/10 - Adaptations for transmission by electrical cable
9.
APPARATUS FOR PROVIDING COMPRESSION IN OPHTHALMIC SURGICAL CASSETTES AND METHODS OF USE THEREOF
Embodiments herein provide a surgical cassette and surgical console for ophthalmic irrigation or aspiration during a surgical procedure, the surgical cassette comprising a plurality of valve assemblies, wherein each valve assembly comprises a retaining ring coupled to a base of the surgical cassette, and a valve body disposed within a cavity defined within the retaining ring, wherein the retaining ring provides a compression force against the valve body that in turn compresses at least a portion of a sealing material disposed on the valve body against a surface of the base. The surgical console comprises a plurality of valve drive assemblies configured to apply additional compression forces to the valve assemblies of the surgical cassette. The valve drive assemblies may be actuated individually or collectively so as to provide additional compression to selected ones of the plurality of valve assemblies.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
10.
SENSOR ASSEMBLY FOR PRESSURE SENSING AND BACK-UP FLUID SUPPLY IN SURGICAL CONSOLES
A back-up infusion pressure sensor module for use in an ophthalmic surgical console includes a squeeze plate configured to engage with a fluid bag. The back-up infusion pressure sensor module further includes a pressure sensor assembly, having a sensor door and a sensor frame, wherein the sensor door pivots relative to a pin coupled to a top portion of the pressure sensor assembly, configured to cause the sensor door to be biased towards the fluid bag. The pressure sensor assembly comprises a base mounted to the back side of the sensor frame of the pressure sensor assembly, one or more springs, a spring bracket coupled to the one or more springs, and a force sensor in contact with the spring bracket, configured to determine a pressure force against the fluid bag.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
In certain embodiments, an ophthalmic system for examining the eye of a patient includes a detector and computer. The detector detects waves reflected from the eye, and the waves convey information about the eye. The detector then generates a detector signal that communicates the information about the eye. The computer performs a contact lens check by determining a characteristic from the eye information indicating the potential presence of a contact lens. The computer generates a notification warning of the potential presence of a contact lens and instructs an output device to provide the notification.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
Embodiments disclosed herein provide a surgical console, a surgical cassette, and a method for utilizing an image sensor to acquire grayscale image(s) and an embedded microcontroller to then process the image(s) to decode the barcode and/or determine the current level of fluid within the surgical cassette. The image sensor is utilized to detect external light that comes into the field of view of the image sensor. A software algorithm stored within a microcontroller in the surgical console determines whether the potential is high for external light interference. If there is a high potential for external light interference, an advisory or alarm is generated to warn the user to remove the external light source or to turn the console away from the external light source. Once the user has removed the external light and then cleared the advisory, normal console operations and functions can resume.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
H04N 23/71 - Circuitry for evaluating the brightness variation
13.
DIAPHRAGM RETAINER RING FOR OPHTHALMIC SURGICAL CASSETTES
Embodiments disclosed herein provide a surgical cassette including pump assemblies with improved contact between a displacement sensor disposed within a surgical console and a diaphragm disposed within the surgical cassette. Each pump assembly includes a diaphragm retainer ring that provides a sufficient creepage and clearance margin, acts as a lead-in for the displacement sensor, assists in preventing misalignment, and provides robustness for the ultrasonic welding process which couples the diaphragm retainer ring to the surgical console. The diaphragm retainer ring is impregnated with a lubricant so to facilitate seating of the displacement sensor with the cassette. A cantilever portion of the diaphragm retainer ring increases a creepage and clearance margin, as well as increases overall part strength in the event of a collision with the displacement sensor and during ultrasonic welding. An insulator is also provided that further increases the creepage and clearance margin.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
14.
CONNECTION DETECTING SYSTEMS FOR A SURGICAL CONSOLE
Embodiments disclosed herein provide a connection detecting system for a surgical console. The connection detection system comprises a port for receiving a connector of a surgical device, an emitter, a detector, and a controller connected to the emitter and the detector. The port comprises a light transmission system comprising a detection zone through which the connector of the surgical device is configured to be disposed when the surgical device is coupled to the surgical console, and a pair of light pipes disposed at opposite ends of the detection zone. The emitter is configured to generate a light for propagation through the light transmission system, and the detector is configured to detect the light propagated through the light transmission system. The controller is configured to determine whether the surgical device is connected to the port based on whether the light is detected by the detector.
An intraocular lens (IOL) configured to support a first optic for functioning as a single lens IOL and configured to support a second optic for functioning as a dual optic IOL. The base includes a first optic for providing a base power. A recess in an anterior rim of the base is configured for positioning a radial extension of a second optic. The geometry of the recess is configured to securely couple to the radial extension to prevent rotation of the second optic relative to the base and prevent tilting of the second optic relative to an optic axis.
Certain embodiments disclosed herein provide an ophthalmic surgical system. The system includes a fluidics module and a controller. The fluidic module includes a surgical cassette bay and one or more indicator lights. The one or more indicator lights correspond to one or more fluidic ports on the fluidics module. The controller includes a memory including executable instructions and a processor. The processor is in data communication with the memory. The processor is configured to execute the instructions to cause the system to: determine that a surgical cassette is coupled to the surgical cassette bay; determine a type of the surgical cassette; illuminate at least one of the one or more indicator lights based on the determined type of the surgical cassette; and extinguish the at least one of the one or more indicator lights upon receiving an input indicating that a fluidic tubing is fluidically coupled with the corresponding fluidic port.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A61B 17/00 - Surgical instruments, devices or methods
Certain embodiments disclosed herein provide a surgical cassette including a housing, one or more retaining rings coupled to the housing, and one or more valve assemblies coupled to the housing by the one or more retaining rings. The one or more valve assemblies configured to control fluid communication between one or more channels within the housing. Each valve assembly includes a valve body having a first end, a second end, a cylindrical surface connecting the first end and second end, and a valve elastomer. The valve elastomer includes a first side configured to couple the valve elastomer to the second end of the valve body and a second side having a recessed surface configured to engage with the housing to form a seal with a base of the housing and reduce mechanical stress across the valve elastomer during rotation of the valve assembly.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
18.
3D PRINTING OF AN INTRAOCULAR LENS HAVING SMOOTH, CURVED SURFACES
A continuous additive fabrication system comprises a bath of photopolymer resin and a light source assembly having a light source and a motorized variable aperture. The light source assembly is operable to generate a focus point in the bath of photopolymer resin, the shape of the focus point at a curing plane within the bath of photopolymer resin corresponding to the shape of the motorized variable aperture. The continuous additive fabrication system further comprises a platform configured to support a build object and a drive mechanism (coupled to at least one of the platform and the light source assembly) configured to continuously move the curing plane through the bath of photopolymer resin. A size and/or shape of the motorized variable aperture is changed while the curing plane in continuously moved through the bath of photopolymer resin.
B29C 64/135 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask the energy source being concentrated, e.g. scanning lasers or focused light sources
A method for cleaning a molding insert for injection-molding of single-use ophthalmic lens molds comprises the steps of providing an insert holder and a molding surface of the molding insert faces away from the insert holder. A dry ice nozzle comprises an inlet for the supply of dry ice, a nozzle channel comprising a longitudinally extending diverging inner wall portion terminating in an outlet opening of the nozzle channel, and a nozzle housing with a circumferentially running distal end wall. The nozzle housing further comprises a housing wall portion extending away from the distal end wall to define an exhaust channel. The method further comprises positioning the dry ice nozzle on the insert holder, supplying dry ice particles to the nozzle inlet to generate a jet of dry ice particles impinging on the molding surface of the molding insert, and removing exhaust gases.
B08B 7/00 - Cleaning by methods not provided for in a single other subclass or a single group in this subclass
B29D 11/00 - Producing optical elements, e.g. lenses or prisms
B05B 1/28 - Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with integral means for shielding the discharged liquid or other fluent material, e.g. to limit area of sprayNozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with integral means for catching drips or collecting surplus liquid or other fluent material
B29L 11/00 - Optical elements, e.g. lenses, prisms
B24C 1/00 - Methods for use of abrasive blasting for producing particular effectsUse of auxiliary equipment in connection with such methods
In certain embodiments, an ophthalmic system for examining the eye of a patient includes a detector and computer. The detector detects waves reflected from the eye, and the waves convey information about the eye. The detector then generates a detector signal that communicates the information about the eye. The computer performs a contact lens check by determining a characteristic from the eye information indicating the potential presence of a contact lens. The computer generates a notification warning of the potential presence of a contact lens and instructs an output device to provide the notification.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
A61B 3/14 - Arrangements specially adapted for eye photography
An illuminated contact lens system for illuminating an interior of a patient's eye includes a contact lens, an external light source, and a light engine. The lens refracts directed light into the eye. The light source emits the directed light toward the eye. The light engine transmits electronic control signals that cause the light source to emit the directed light. A prism array connected to an annular tube containing the light source may optionally shape the directed light into a conical distribution pattern. A control board may drive the light source in response to the electronic control signals, and may be optionally used as a proximity sensor. A method includes receiving the electronic control signals from the light engine via the control board, illuminating the light source, and emitting the directed light from the toward the eye.
A method for cleaning a molding insert for injection-molding of single-use ophthalmic lens molds comprises the steps of providing an insert holder and a molding surface of the molding insert faces away from the insert holder. A dry ice nozzle comprises an inlet for the supply of dry ice, a nozzle channel comprising a longitudinally extending diverging inner wall portion terminating in an outlet opening of the nozzle channel, and a nozzle housing with a circumferentially running distal end wall. The nozzle housing further comprises a housing wall portion extending away from the distal end wall to define an exhaust channel. The method further comprises positioning the dry ice nozzle on the insert holder, supplying dry ice particles to the nozzle inlet to generate a jet of dry ice particles impinging on the molding surface of the molding insert, and removing exhaust gases.
B29C 45/17 - Component parts, details or accessoriesAuxiliary operations
B08B 15/04 - Preventing escape of dirt or fumes from the area where they are producedCollecting or removing dirt or fumes from that area from a small area, e.g. a tool
B24C 1/00 - Methods for use of abrasive blasting for producing particular effectsUse of auxiliary equipment in connection with such methods
B29C 31/00 - Handling, e.g. feeding of the material to be shaped
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mouldApparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
B29D 11/00 - Producing optical elements, e.g. lenses or prisms
B29L 11/00 - Optical elements, e.g. lenses, prisms
A control system for an ultrasonic hand piece is provided. The control system includes an irrigation pressure sensor configured to measure a pressure of an irrigation fluid, an ultrasonic power source configured to provide power to an ultrasonic transducer, and a controller. The controller is configured to receive a selection of an ultrasonic power modality, generate a control signal based on the selected ultrasonic power modality, provide the control signal to the ultrasonic power source, determine an irrigation flow rate from a measured irrigation pressure provided by the irrigation pressure sensor, calculate a thermal index value based on the irrigation flow rate and the selected ultrasonic power modality, and, in response to the thermal index value reaching a threshold value, adjust the control signal based on the thermal index value. The ultrasonic power modality is one of a two dimensional power modality and a three dimensional power modality.
An ophthalmic system for measuring an eye comprises measuring devices and a computer. The measuring devices comprise an optical coherence tomography (OCT) device and an aberrometer. The OCT device directs OCT light towards the eye, and detects the OCT light reflected from the eye to measure the eye. The aberrometer directs aberrometer light towards the eye, and detects the aberrometer light reflected from the eye to measure the eye. The computer generates an ocular model of the eye according to the reflected OCT light. The ocular model comprises parameters for the eye, where each parameter is assigned a value. The computer determines an OCT-based wavefront according to the ocular model, determines an aberrometer-based wavefront according to the reflected aberrometer light, ascertains a deviation between the OCT-based wavefront and the aberrometer-based wavefront, and evaluates measurements from one or more of the measuring devices according to the deviation.
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A control system for an ultrasonic hand piece is provided. The control system includes an irrigation pressure sensor configured to measure a pressure of an irrigation fluid, an ultrasonic power source configured to provide power to an ultrasonic transducer, and a controller. The controller is configured to receive a selection of an ultrasonic power modality, generate a control signal based on the selected ultrasonic power modality, provide the control signal to the ultrasonic power source, determine an irrigation flow rate from a measured irrigation pressure provided by the irrigation pressure sensor, calculate a thermal index value based on the irrigation flow rate and the selected ultrasonic power modality, and, in response to the thermal index value reaching a threshold value, adjust the control signal based on the thermal index value. The ultrasonic power modality is one of a two dimensional power modality and a three dimensional power modality.
Embodiments disclosed herein provide a clamp assembly for engaging a surgical cassette with an ophthalmic surgical console. The clamp assembly includes a motion plate and a plurality of clamp mechanisms coupled to the motion plate. A plurality of bases which remain in a fixed position are also coupled to each of the plurality of clamp mechanisms and to a face plate portion of a fluidics subsystem of the ophthalmic surgical console. A motion plate motor is provided which serves to move the motion plate in a vertical direction relative to the face plate. As the motion plate is vertically displaced, the clamp mechanisms coupled thereto are opened and expanded into the surgical cassette, thereby pressing it against the face plate and ensuring any connections and seals between the face plate and the surgical cassette are established and maintained.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
28.
HERMETICALLY SEALED FIBER OPTICS WITH PROTECTIVE WINDOW
Embodiments disclosed herein provide an optical fiber system. The optical fiber system includes an optical fiber, a distal window, and a proximal assembly. The distal window is disposed on a distal end of the optical fiber. The proximal assembly includes a proximal ferrule and a proximal window. The proximal window and the distal window comprise a sapphire material or a diamond material.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
29.
PRODUCTION LINE FOR THE PRODUCTION OF OPHTHALMIC LENSES
An automated production line for the production of ophthalmic lenses comprises:
a production line front end (1) comprising:
a first injection-molding machine (10) and a second injection-molding machine (12)
a casting module (14) comprising
a filling station (144) and a capping station (145);
a stacking module (15) and a curing module (16);
a destacking module (17) and a demolding and delensing module
a production line back end (2) comprising:
a scalable treatment module (20) comprising a number of liquid baths for a liquid bath treatment of the cured lenses (CL) carried by the treatment carrier tray (200) to obtain the ophthalmic lenses, wherein the number of liquid baths are reduced or increased pending on the number of ophthalmic lenses concurrently produced by the production lines.
An ophthalmic system for generating an ocular model of an eye includes an optical coherence tomography (OCT) device, an aberrometer, and a computer. The OCT device detects OCT light reflected from the eye. The aberrometer detects aberrometer light reflected from the eye. The computer generates the ocular model of the eye according to the reflected OCT light. The ocular model includes parameters describing the eye. The parameters include lens parameters that describe the lens of the eye. The computer determines an OCT-based wavefront according to the ocular model, determines an aberrometer-based wavefront according to the reflected aberrometer light, and compares the OCT-based and the aberrometer-based wavefronts. If the wavefronts differ beyond a predefined tolerance, the computer adjusts one or more values assigned to the parameters until the wavefronts satisfy the predefined tolerance. At least one adjusted value is assigned to a lens parameter.
Embodiments disclosed herein provide a clamp assembly for engaging a surgical cassette with an ophthalmic surgical console. The clamp assembly includes a motion plate and a plurality of clamp mechanisms coupled to the motion plate. A plurality of bases which remain in a fixed position are also coupled to each of the plurality of clamp mechanisms and to a face plate portion of a fluidics subsystem of the ophthalmic surgical console. A motion plate motor is provided which serves to move the motion plate in a vertical direction relative to the face plate. As the motion plate is vertically displaced, the clamp mechanisms coupled thereto are opened and expanded into the surgical cassette, thereby pressing it against the face plate and ensuring any connections and seals between the face plate and the surgical cassette are established and maintained.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
Embodiments disclosed herein provide an optical fiber system. The optical fiber system includes an optical fiber, a distal window, and a proximal assembly. The distal window is disposed on a distal end of the optical fiber. The proximal assembly includes a proximal ferrule and a proximal window. The proximal window and the distal window comprise a sapphire material or a diamond material.
Disclosed are adjustable intraocular lenses and methods of adjusting intraocular lenses post-operatively. In one embodiment, an adjustable intraocular lens can comprise an optic portion and one or more haptics. The optic portion can comprise an anterior element, a posterior element, and a fluid-filled optic chamber. At least part of the optic portion can be made of a composite material. The base power of the optic portion can be configured to change in response to an external energy directed at the composite material.
Systems and methods are disclosed for a surgical laser system with illumination. In some embodiments, a laser system comprises a surgical laser and an illumination source having their outputs combined into a fiber-optic cable and directed by the fiber-optic cable to a target surface. The illuminating visible light may be continuous and/or in pulses. Surgical laser pulses and illumination pulses may be synchronized for a stroboscopic effect. The laser system may also monitor laser electromagnetic radiation that is returned back through the fiber-optic cable.
Provided in this document are examples of a multifocal ophthalmic lens. The lens includes a base lens having a base curvature corresponding to a base power; and a diffractive structure comprising a plurality of annular echelettes formed on a first surface of the base lens. The diffractive structure is configured to produce a zero-order diffraction corresponding to a distance vision focal point determined by the base power, the diffraction efficiency of the zero-order diffraction between 45% and 55%; a first-order diffraction having a diffraction efficiency between 5% and 10%; a second-order diffraction corresponding to an intermediate vision focal point, the diffraction efficiency between 15% and 20%; and a third-order diffraction corresponding to a near vision focal point, the diffraction efficiency between 15% and 25%. The diffractive structure includes a plurality of annular diffractive steps, each defined by a profile having a curved slope and a peak.
In a method of handling an ophthalmic lens contained in an inspection cuvette and immersed in an inspection liquid the lens is arranged at an actual position relative to a concave inner surface of a bottom glass of the inspection cuvette; The method comprises the steps of: - positioning the inspection cuvette in a handling position without pivoting the inspection cuvette; - through the viewing glass obtaining an image of the lens; - from the obtained image determining a deviation of the actual position of the lens from a set transfer position; - comparing the deviation with a predetermined maximum deviation; - determining that the lens is arranged at a proper transfer position when the deviation is less than the maximum deviation, - in case of the proper transfer position, transferring the lens from the inspection cuvette to the primary packaging container.
Provided herein are methods of synthesizing netarsudil, and intermediates thereof, in high yield and at large commercial scale. A key intermediate in this synthesis is the preparation of piperidinium (S)-3-((tert-butoxycarbonyl)amino)-2-(4-(((2,4-dimethylbenzoyl)oxy)methyl)phenyl)propanoate, a salt that has been found to be easily purified by recrystallization.
C07D 217/16 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
C07C 211/63 - Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
C07C 211/64 - Quaternary ammonium compounds having quaternised nitrogen atoms bound to carbon atoms of six-membered aromatic rings
C07C 229/38 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
C07D 295/023 - PreparationSeparationStabilisationUse of additives
In certain embodiments, a dispensing plug (403) includes a fluid path having an inlet and an outlet. The dispensing plug (403) also includes a valve (405) adjustably disposed relative to the fluid path. The valve (405) includes a first valve portion (422) positioned in the fluid path between the inlet and the outlet. The valve (405) also includes a second valve portion oriented to cause a first force to be exerted on the first valve portion. The first force biases the first valve portion toward closure of the fluid path.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
B65D 47/18 - Closures with discharging devices other than pumps with pouring spouts or tubesClosures with discharging devices other than pumps with discharge nozzles or passages for discharging dropsDroppers
39.
INTRAOCULAR LENSES WITH ADJUSTABLE OPTIC PORTIONS AND METHODS OF POST-OPERATIVELY ADJUSTING INTRAOCULAR LENSES
Disclosed are adjustable intraocular lenses and methods of adjusting intraocular lenses post-operatively. In one embodiment, an adjustable intraocular lens (100) can comprise an optic portion (102) and one or more haptics (104). The optic portion (102) can comprise an anterior element (106), a posterior element (108), and a fluid-filled optic chamber (110). At least part of the optic portion (102) can be made of a composite material. The base power of the optic portion (102) can be configured to change in response to an external energy directed at the composite material.
A61F 9/008 - Methods or devices for eye surgery using laser
A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
40.
INTEGRATED INTRAOCCULAR NAVIGATION SYSTEM FOR OPHTHALMIC SURGERY
A system includes an imaging device configured to perform three-dimensional imaging of at least a portion of an eye of a patient, such as one or both of an OCT and a 3D camera. A sensor is configured to sense a location of a trocar cannula positioned in the eye of the patient. A controller is configured to receive one or more three-dimensional images from the imaging device and receive coordinates of the trocar cannula from the sensor. The controller generates a three-dimensional map of the eye from the one or more three-dimensional images and the coordinates, the three-dimensional map including a representation of the trocar cannula. The controller further generates guidance for performing an ophthalmic procedure according to the three-dimensional map, such as an instrument envelope and/or instrument path. The controller outputs the guidance to a display device or uses the guidance to control a robotic arm.
In certain embodiments, a dispensing plug includes a fluid path having an inlet and an outlet. The dispensing plug also includes a valve adjustably disposed relative to the fluid path. The valve includes a first valve portion positioned in the fluid path between the inlet and the outlet. The valve also includes a second valve portion oriented to cause a first force to be exerted on the first valve portion. The first force biases the first valve portion toward closure of the fluid path.
In a method of handling an ophthalmic lens contained in an inspection cuvette and immersed in an inspection liquid the lens is arranged at an actual position relative to a concave inner surface of a bottom glass of the inspection cuvette;
In a method of handling an ophthalmic lens contained in an inspection cuvette and immersed in an inspection liquid the lens is arranged at an actual position relative to a concave inner surface of a bottom glass of the inspection cuvette;
The method comprises the steps of:
positioning the inspection cuvette in a handling position without pivoting the inspection cuvette;
through the viewing glass obtaining an image of the lens;
from the obtained image determining a deviation of the actual position of the lens from a set transfer position;
comparing the deviation with a predetermined maximum deviation;
determining that the lens is arranged at a proper transfer position when the deviation is less than the maximum deviation,
in case of the proper transfer position, transferring the lens from the inspection cuvette to the primary packaging container.
Systems and methods for intraocular lens selection include obtaining one or more pre-operative measurements of an eye; selecting, from a plurality of historical IOL implantation records, a subset of historical IOL implantation records for evaluating a first plurality of prediction model candidates; evaluating the first plurality of prediction model candidates; selecting a first prediction model from the first plurality of prediction model candidates based on the evaluating; calculating, using the selected first prediction model, a plurality of estimated post-operative MRSE values based on a set of IOL powers and the one or more pre-operative measurements of the eye; determining a first IOL power corresponding to a first estimated post-operative MRSE value that matches a predetermined post-operative MRSE value; and providing the determined first IOL power to a user to aid in selection of an IOL for implantation in the eye.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A lens drying system includes a sterile gas supply, a supply line, and an annular body. The body is connected to the supply line and defines an internal channel. The internal channel, which is in fluid communication with the sterile gas supply via the supply line, defines a plurality of openings. The openings are collectively configured to direct a flow of a sterile gas, e.g., a filtered and desiccated medical grade gas, from the sterile gas supply onto a lens surface of an ophthalmic front lens. This occurs during a non-contact wide-angle visualization process to mitigate fogging of the lens surface. A processor of a surgical console may receive user preference settings, including a desired steady-state flow rate and/or a desired pulse rate of the sterile gas. The processor could then command the desired steady-state flow rate and/or a desired pulse rate from the surgical console.
Provided in this document are examples of a multifocal ophthalmic lens. The lens includes a base lens having a base curvature corresponding to a base power; and a diffractive structure comprising a plurality of annular echelettes formed on a first surface of the base lens. The diffractive structure is configured to produce a zero-order diffraction corresponding to a distance vision focal point determined by the base power, the diffraction efficiency of the zero-order diffraction between 45% and 55%; a first-order diffraction having a diffraction efficiency between 5% and 10%; a second-order diffraction corresponding to an intermediate vision focal point, the diffraction efficiency between 15% and 20%; and a third-order diffraction corresponding to a near vision focal point, the diffraction efficiency between 15% and 25%. The diffractive structure includes a plurality of annular diffractive steps, each defined by a profile having a curved slope and a peak.
A system includes an imaging device configured to perform three-dimensional imaging of at least a portion of an eye of a patient, such as one or both of an OCT and a 3D camera. A sensor is configured to sense a location of a trocar cannula positioned in the eye of the patient. A controller is configured to receive one or more three-dimensional images from the imaging device and receive coordinates of the trocar cannula from the sensor. The controller generates a three-dimensional map of the eye from the one or more three-dimensional images and the coordinates, the three-dimensional map including a representation of the trocar cannula. The controller further generates guidance for performing an ophthalmic procedure according to the three-dimensional map, such as an instrument envelope and/or instrument path. The controller outputs the guidance to a display device or uses the guidance to control a robotic arm.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A digital ocular system includes a housing, an eye piece having a lens assembly. A display screen, a proximity sensor, and a processor. The lens assembly includes a front lens through which a user of the digital ocular system views a target object. The display screen is positioned within the housing cavity. The proximity sensor, which is connected to the housing, detects when user is within a predetermined standoff distance of the front lens, and outputs an electronic sensor signal when the user is outside of the predetermined standoff distance, i.e., not detected. The processor is configured to adjust an output state of the display screen via a display control signal in response to the electronic sensor signal.
The disclosure provides a method for correcting higher-order aberrations including providing a laser radiation. The method also includes controlling a location of a beam focal point of the laser radiation by a system of scanners and guiding the beam focal point in such a way that the location of the beam focal point is in a cornea of an eye. The method further includes introducing the laser radiation into the cornea of the eye. The method includes cutting a lenslet, wherein a thickness of the lenslet t(X,Y) satisfies a following equation: t(X,Y)=t0+Δt(X,Y)/(n−1), where Δt(X,Y) represents a higher-order wavefront elevation and t0 represents the thickness of the lenslet having a spherical refractive power of D.
Embodiments disclosed herein relate to devices and systems for use in ophthalmic procedures. In some embodiments, a handpiece device for use with a surgical system is provided. The handpiece device includes a housing, a cable assembly, and a tapered optical fiber. The cable assembly is disposed through a distal end of the housing and optically coupled to the tapered optical fiber. The tapered optical fiber has a diameter that decreases between a proximal end of the tapered optical fiber and a distal end thereof. In some embodiments, the tapered optical fiber comprises a single-crystal fiber. In further embodiments, the tapered optical fiber comprises a tapered sapphire core fiber.
Certain aspects of the present disclosure provide systems and methods for measuring eye- tissue biomechanics via blink stimulation. In certain embodiments, a method may be performed by a computer in communication with an optical coherence tomography (OCT) device. The method includes monitoring movement relative to an eye of a patient via one or more images from a camera. The method also includes detecting a blink of the eye of the patient responsive to the monitoring. The method also includes, responsive to the detected blink, recording data resultant from a scan, by the OCT device, of at least a portion of a tissue of the eye. The method also includes measuring a tissue response to the detected blink based on the recorded data from the scan.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
54.
POLARIZATION SENSITIVE OPTICAL COHERENCE TOMOGRAPHY FOR VISUALIZATION OF VITREOUS OPACITIES
A system of visualizing a target site in an eye, using a polarization sensitive optical coherence tomography (PS-OCT) device, includes a controller having at least one processor and at least one non-transitory, tangible memory on which instructions are recorded. The target site is one or more vitreous opacities in the vitreous humor of the eye. The controller is configured to receive PS-OCT data and determine at least one parameter corresponding to birefringence properties of collagen fibrils in the vitreous humor based on the PS-OCT data. The at least one parameter includes respective spacing of the collagen fibrils. The controller is configured to determine a respective location of the one or more vitreous opacities when the at least one parameter is outside a predefined range and generate a control signal adapted for guiding a treatment beam at the respective location of the one or more vitreous opacities.
A system for performing ophthalmic surgery includes a robotic positioning system including an end effector. The robotic positioning system is configured to position the end effector with at least five degrees of freedom. An ophthalmic surgical instrument is mounted to the end effector along with an accessory device configured to facilitate performance of an ophthalmic treatment by the ophthalmic surgical instrument. The robotic positioning system may be controlled to enforce anatomical boundaries and implement predefined motion profiles.
The present disclosure provides an intralocular-lens (IOL) or ophthalmic device including an optic and at least one haptic, at least a portion of which is formed from a photoresponsive shape memory polymer network, such as a polydomain azo liquid crystalline polymer network (PD-LCN). The present disclosure further provides systems and methods for adjusting the position of such an IOL or other ophthalmic device using polarized laser radiation.
A lens drying system includes a sterile gas supply, a supply line, and an annular body. The body is connected to the supply line and defines an internal channel. The internal channel, which is in fluid communication with the sterile gas supply via the supply line, defines a plurality of openings. The openings are collectively configured to direct a flow of a sterile gas, e.g., a filtered and desiccated medical grade gas, from the sterile gas supply onto a lens surface of an ophthalmic front lens. This occurs during a non-contact wide-angle visualization process to mitigate fogging of the lens surface. A processor of a surgical console may receive user preference settings, including a desired steady-state flow rate and/or a desired pulse rate of the sterile gas. The processor could then command the desired steady-state flow rate and/or a desired pulse rate from the surgical console.
A system of visualizing a target site in an eye, using a polarization sensitive optical coherence tomography (PS-OCT) device, includes a controller having at least one processor and at least one non-transitory, tangible memory on which instructions are recorded. The target site is one or more vitreous opacities in the vitreous humor of the eye. The controller is configured to receive PS-OCT data and determine at least one parameter corresponding to birefringence properties of collagen fibrils in the vitreous humor based on the PS-OCT data. The at least one parameter includes respective spacing of the collagen fibrils. The controller is configured to determine a respective location of the one or more vitreous opacities when the at least one parameter is outside a predefined range and generate a control signal adapted for guiding a treatment beam at the respective location of the one or more vitreous opacities.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
G02B 27/28 - Optical systems or apparatus not provided for by any of the groups , for polarising
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
59.
SPATIAL BINDING OF IMAGING DATA FROM MULTIPLE MODALITIES
A system for spatially binding images from multiple modalities includes a controller having at least one processor and at least one non-transitory, tangible memory. The controller is adapted to receive first and second imaging datasets of a target site from a first and a second modality. The controller is adapted to extract a first feature set in the first imaging dataset, via a first neural network. A second feature set is extracted from the second imaging dataset, via a second neural network. Feature pairs are generated by matching respective datapoints in the first feature set and the second feature set. The controller is adapted to determine a coordinate transformation between the feature pairs and generate at least one spatially bound image of the target site based in part on the coordinate transformation.
G06T 7/33 - Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
G06V 10/75 - Organisation of the matching processes, e.g. simultaneous or sequential comparisons of image or video featuresCoarse-fine approaches, e.g. multi-scale approachesImage or video pattern matchingProximity measures in feature spaces using context analysisSelection of dictionaries
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
G06V 20/70 - Labelling scene content, e.g. deriving syntactic or semantic representations
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
Ophthalmic viewing systems for visualizing structures on and in an eye of a medical patient include an ophthalmic microscope, a gonioscopy device configured to work with the ophthalmic microscope to provide an image of an interior of the patient's eye, and a robotic arm configured to hold the gonioscopy device in a position in relation to the ophthalmic microscope and the patient's eye to provide the image of the eye's interior.
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
A digital ocular system includes a housing, an eye piece having a lens assembly. A display screen, a proximity sensor, and a processor. The lens assembly includes a front lens through which a user of the digital ocular system views a target object. The display screen is positioned within the housing cavity. The proximity sensor, which is connected to the housing, detects when user is within a predetermined standoff distance of the front lens, and outputs an electronic sensor signal when the user is outside of the predetermined standoff distance, i.e., not detected. The processor is configured to adjust an output state of the display screen via a display control signal in response to the electronic sensor signal.
Embodiments disclosed herein provide an optical fiber system. The optical fiber system includes an aspiration tube, an optical fiber external to the aspiration tube, and a sleeve surrounding the optical fiber and the aspiration tube. The sleeve includes a distal portion that defines a channel. The channel extends between the aspiration tube and a distal opening of the sleeve. The channel and the aspiration tube define an aspiration pathway. The optical fiber is partially disposed within the channel.
The present disclosure generally relates to systems and methods for laser alignment, and more particularly, systems and methods for alignment of an optical element for laser transmission. In certain embodiments, a cover plate is configured to slide into place on an optic mounting plate. Positioning the cover plate applies force to a biasing element to press an optical element against a registration surface of the optic mounting plate to align the optical element with an optical aperture. The cover plate may be secured relative to the optic mounting plate to retain the biasing element and the optical element.
A system for spatially binding images from multiple modalities includes a controller having at least one processor and at least one non-transitory, tangible memory. The controller is adapted to receive first and second imaging datasets of a target site from a first and a second modality. The controller is adapted to extract a first feature set in the first imaging dataset, via a first neural network. A second feature set is extracted from the second imaging dataset, via a second neural network. Feature pairs are generated by matching respective datapoints in the first feature set and the second feature set. The controller is adapted to determine a coordinate transformation between the feature pairs and generate at least one spatially bound image of the target site based in part on the coordinate transformation.
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
G06V 10/80 - Fusion, i.e. combining data from various sources at the sensor level, preprocessing level, feature extraction level or classification level
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
G06V 40/18 - Eye characteristics, e.g. of the iris
G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]
Ophthalmic viewing systems for visualizing structures on and in an eye of a medical patient include an ophthalmic microscope, a gonioscopy device configured to work with the ophthalmic microscope to provide an image of an interior of the patient's eye, and a robotic arm configured to hold the gonioscopy device in a position in relation to the ophthalmic microscope and the patient's eye to provide the image of the eye's interior.
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
Embodiments disclosed herein provide an optical fiber system. The optical fiber system includes an aspiration tube, an optical fiber external to the aspiration tube, and a sleeve surrounding the optical fiber and the aspiration tube. The sleeve includes a distal portion that defines a channel. The channel extends between the aspiration tube and a distal opening of the sleeve. The channel and the aspiration tube define an aspiration pathway. The optical fiber is partially disposed within the channel.
The present disclosure generally relates to systems and methods for laser alignment, and more particularly, systems and methods for alignment of an optical element for laser transmission. In certain embodiments, a cover plate is configured to slide into place on an optic mounting plate. Positioning the cover plate applies force to a biasing element to press an optical element against a registration surface of the optic mounting plate to align the optical element with an optical aperture. The cover plate may be secured relative to the optic mounting plate to retain the biasing element and the optical element.
A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
In certain embodiments, an ophthalmic lens includes an optic having an anterior surface, a posterior surface, and an optical axis. At least one of the anterior surface and the posterior surface includes a first zone extending from the optical axis to a first radial boundary and a second zone extending from the first radial boundary to the edge of the optic. The first zone includes an inner region and an outer region separated by a phase shift feature, the phase shift comprising a ridge extending outwardly from the inner region and the outer region.
Systems and methods for tracking the position and condition of an eye during an ophthalmic procedure include an ophthalmic device configured to measure characteristics of an eye, an eye tracker configured to capture a stream of eye images, and a logic device configured to analyze the stream of images to determine whether the eye is fixating on a target object, detect a predetermined blink sequence in the first stream of images, delay for a predetermined tear stabilization period, start a stable tear film interval, and during the stable tear film interval, capture at least one measurement of the eye using the ophthalmic device when the eye is fixating. The blink sequence may include a plurality of blinks in succession and the detection of the blink sequence may include processing the images through a neural network trained to detect an open eye and/or a closed eye.
A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/14 - Arrangements specially adapted for eye photography
Systems, methods, and computer-readable media for integrating and optimizing a surgical suite. An ophthalmic suite can include a surgical console, a heads-up display communicatively coupled with a surgical camera for capturing a three-dimensional image of an eye, and a surgical suite optimization engine. The surgical suite optimization engine can performs a wide variety of actions in response to action codes received from the other components in the surgical suite. The surgical suite optimization engine can be integrated within another component of the surgical suite, can be a stand-alone module, and can be a cloud-based tool.
A61B 34/00 - Computer-aided surgeryManipulators or robots specially adapted for use in surgery
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 17/00 - Surgical instruments, devices or methods
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61B 90/98 - Identification means for patients or instruments, e.g. tags using electromagnetic means, e.g. transponders
A61F 9/008 - Methods or devices for eye surgery using laser
Embodiments disclosed herein relate to devices and systems for use in ophthalmic procedures. In some embodiments, a handpiece device for use with a surgical system is provided. The handpiece device includes a housing, a cable assembly, and a tapered optical fiber. The cable assembly is disposed through a distal end of the housing and optically coupled to the tapered optical fiber. The tapered optical fiber has a diameter that decreases between a proximal end of the tapered optical fiber and a distal end thereof. In some embodiments, the tapered optical fiber comprises a single-crystal fiber. In further embodiments, the tapered optical fiber comprises a tapered sapphire core fiber.
A61F 9/008 - Methods or devices for eye surgery using laser
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
72.
MEASURING EYE-TISSUE BIOMECHANICS VIA BLINK STIMULATION
Certain aspects of the present disclosure provide systems and methods for measuring eye-tissue biomechanics via blink stimulation. In certain embodiments, a method may be performed by a computer in communication with an optical coherence tomography (OCT) device. The method includes monitoring movement relative to an eye of a patient via one or more images from a camera. The method also includes detecting a blink of the eye of the patient responsive to the monitoring. The method also includes, responsive to the detected blink, recording data resultant from a scan, by the OCT device, of at least a portion of a tissue of the eye. The method also includes measuring a tissue response to the detected blink based on the recorded data from the scan.
A system for performing ophthalmic surgery includes a robotic positioning system including an end effector. The robotic positioning system is configured to position the end effector with at least five degrees of freedom. An ophthalmic surgical instrument is mounted to the end effector along with an accessory device configured to facilitate performance of an ophthalmic treatment by the ophthalmic surgical instrument. The robotic positioning system may be controlled to enforce anatomical boundaries and implement predefined motion profiles.
An optical coherence tomography (OCT) scanning system for measuring ocular tissue characteristics of a patient's eye. The system includes an OCT scanner configured to implement a scanning sequence on the ocular tissue that scans the ocular tissue with an optical signal to obtain OCT data based on a reflected version of the optical signal. The system includes a computer with a processor configured to provide control signals to the OCT scanner to implement the scanning sequence, and to determine a rate of change of the phase or amplitude data associated with the scans. The system determines a growth constant of the reflected version of the optical signal based on the rate of change of the phase or amplitude data, and determines, based on the growth constant, a diffusion coefficient associated with the cornea. The system determines, based on the diffusion coefficient, a quantitative parameter of the cornea.
In certain embodiments, a surgical handpiece system includes a phacoemulsification tip, a fluid management system, an ultrasonic drive system, and a controller. The phacoemulsification tip is attached to a shaft. The fluid management system is configured to manage inflow and outflow of fluid from an ocular surgical site. The ultrasonic drive system is configured to generate torsional and longitudinal vibrations in the phacoemulsification tip. The controller is configured to analyze applied voltage and current to the ultrasonic drive system using Fast Fourier Transforms (FFTs), and tune applied frequencies of the torsional and longitudinal vibrations according to at least one resonant frequency.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
Described herein is a system for surgical procedures. The system can include a tray and a wireless remote. The tray may include a magnetically attractive layer. The wireless remote is configured to control one or more aspects associated with operations of a surgical console and includes one or more magnets configured to magnetically interact with the magnetically attractive layer and couple the wireless remote to the tray.
A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.
A61F 9/008 - Methods or devices for eye surgery using laser
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
78.
MEASURING BIOMECHANICS IN REAL TIME AT MULTIPLE EYE-TISSUE LOCATIONS
Certain aspects of the present disclosure provide systems and methods for measuring biomechanics in real-time at multiple eye-tissue locations. In certain embodiments, a method may be performed by a computer in communication with an optical coherence tomography (OCT) device. The method includes receiving an indication of a stimulus applied to eye tissue of a patient. The method also includes instructing the OCT device to emit a plurality of beams, at approximately the same time, to a plurality of measurement locations on the eye tissue in response to the received indication. The method also includes receiving, from the OCT device, OCT data for each of the plurality of measurement locations. The method also includes measuring tissue responses to the stimulus at the plurality of measurement locations based on the OCT data.
Described herein include a system and method for a device for drug delivery and ophthalmic diagnostics designed to assist in the diagnosis of the physical state of a cornea through the projection of droplets onto the eye. In some embodiments, the apparatus includes a liquid sampling unit, an electric droplet generator, and a steering unit. In some embodiments, the liquid sampling unit is configured to project a quantity of liquid, while the electric droplet generator receives the quantity of liquid and outputs one or more electrically charged droplets. The steering unit uses electrostatic forces to steer the electrically charged droplets along a trajectory onto the cornea of the patient's eye.
A61B 3/16 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring intraocular pressure, e.g. tonometers
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61M 15/02 - Inhalators with activated or ionized gasesOzone-inhalators
B05B 17/06 - Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass operating with special methods using ultrasonic vibrations
80.
DEVICE AND METHOD FOR MEASURING OCULAR TISSUE CHARACTERISTICS
An optical coherence tomography (OCT) scanning system for measuring ocular tissue characteristics of a patient's eye. The system includes an OCT scanner configured to implement a scanning sequence on the ocular tissue that scans the ocular tissue with an optical signal to obtain OCT data based on a reflected version of the optical signal. The system includes a computer with a processor configured to provide control signals to the OCT scanner to implement the scanning sequence, and to determine a rate of change of the phase or amplitude data associated with the scans. The system determines a growth constant of the reflected version of the optical signal based on the rate of change of the phase or amplitude data, and determines, based on the growth constant, a diffusion coefficient associated with the cornea. The system determines, based on the diffusion coefficient, a quantitative parameter of the cornea.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
81.
SYSTEM AND METHOD FOR A SURGICAL HANDPIECE AND MULTI-MODAL TIP
In certain embodiments, a surgical handpiece system includes a phacoemulsification tip, a fluid management system, an ultrasonic drive system, and a controller. The phacoemulsification tip is attached to a shaft. The fluid management system is configured to manage inflow and outflow of fluid from an ocular surgical site. The ultrasonic drive system is configured to generate torsional and longitudinal vibrations in the phacoemulsification tip. The controller is configured to analyze applied voltage and current to the ultrasonic drive system using Fast Fourier Transforms (FFTs), and tune applied frequencies of the torsional and longitudinal vibrations according to at least one resonant frequency.
The present disclosure generally relates to port connector assemblies for delivering infusion gases during ophthalmic surgeries and procedures. In some embodiments, the connector assembly includes a connector for a surgical console and a corresponding receiver for connecting the connector to the surgical console.
A61M 39/12 - Tube connectors or tube couplings for joining a flexible tube to a rigid attachment
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
83.
SYSTEM AND METHOD FOR PERFORMING OPHTHALMIC LASER ASSISTED SURGERY WITH IMMERSION LIQUIDS
Disclosed herein is a method of performing ophthalmic surgery. The surgery includes positioning a patient interface relative to a patient's eye with the patient interface at least partially defining an interface chamber with the patient's eye. The interface chamber is filled with an immersion fluid. A fluid in an anterior chamber of the patient's eye is replaced with the immersion fluid, wherein the immersion fluid matches the refractive index of the cornea. A laser system is positioned relative to the patient interface. The laser system includes a laser source configured to generate a femtosecond laser beam and an optical delivery and scanner system in communication with the laser source to direct 3D scanned and focused laser beams through the patient interface and into the patient's eye.
A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.
Certain aspects of the present disclosure provide systems (10) and methods (800) for measuring biomechanics in real-time at multiple eye-tissue locations. In certain embodiments, a method (800) may be performed by a computer (30) in communication with an optical coherence tomography, OCT, device (15, 315). The method includes receiving an indication of a stimulus applied to eye tissue (346) of a patient (42). The method also includes instructing the OCT device (15, 315) to emit a plurality of beams (344, 560, 660), at approximately the same time, to a plurality of measurement locations (772) on the eye tissue (346) in response to the received indication. The method (800) also includes receiving, from the OCT device (15, 315), OCT data for each of the plurality of measurement locations (772). The method (800) also includes measuring tissue responses to the stimulus at the plurality of measurement locations based on the OCT data.
A system for performing ophthalmic treatments includes a handpiece configured to be held by a hand of a surgeon. An end effector is mounted to the handpiece and configured to manipulate tissue of a patient, such tissues of the eye when performing an ophthalmic treatment. The system includes a motion sensor configured to sense movement of the handpiece and one or more stabilizing actuators configured to stabilize movement of the handpiece in response to movement of the hand of the surgeon. A controller is coupled to the motion sensor and the one or more stabilizing actuators and is configured to instruct the one or more stabilizing actuators to compensate for motion detected by the motion sensor. The controller may include a high-pass filer with the output of the high-pass filter used to control the stabilizing actuators. The parameters of the high pass filter may be adjusted throughout an ophthalmic treatment.
Described herein include a system and method for a device for drug delivery and ophthalmic diagnostics designed to assist in the diagnosis of the physical state of a cornea through the projection of droplets onto the eye. In some embodiments, the apparatus includes a liquid sampling unit, an electric droplet generator, and a steering unit. In some embodiments, the liquid sampling unit is configured to project a quantity of liquid, while the electric droplet generator receives the quantity of liquid and outputs one or more electrically charged droplets. The steering unit uses electrostatic forces to steer the electrically charged droplets along a trajectory onto the cornea of the patient's eye.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
88.
SYSTEM AND METHOD FOR PERFORMING OPHTHALMIC LASER ASSISTED SURGERY WITH IMMERSION LIQUIDS
Disclosed herein is a method of performing ophthalmic surgery. The surgery includes positioning a patient interface relative to a patient's eye with the patient interface at least partially defining an interface chamber with the patient's eye. The interface chamber is filled with an immersion fluid. A fluid in an anterior chamber of the patient's eye is replaced with the immersion fluid, wherein the immersion fluid matches the refractive index of the cornea. A laser system is positioned relative to the patient interface. The laser system includes a laser source configured to generate a femtosecond laser beam and an optical delivery and scanner system in communication with the laser source to direct 3D scanned and focused laser beams through the patient interface and into the patient's eye.
The present disclosure generally relates to port connector assemblies for delivering infusion gases during ophthalmic surgeries and procedures. In some embodiments, the connector assembly includes a connector for a surgical console and a corresponding receiver for connecting the connector to the surgical console.
Systems and methods for measuring corneal biomechanical properties are provided. In certain embodiments, a method comprises determining a plurality of optical coherence tomography (OCT) measurement locations in a region of a cornea; for each OCT measurement location: applying a mechanical excitation to the cornea at the OCT measurement location, and measuring a response of the cornea to the mechanical excitation by acquiring temporal OCT data at the OCT measurement location; generating temporal deformation data for the region of the cornea based on the temporal OCT data at each OCT measurement location; and generating biomechanical data for the region of the cornea based on the temporal deformation data.
A system and method for corneal cross-linking with real-time monitoring are provided. The method comprises determining a plurality of measurement locations in a region of a cornea, and applying a corneal cross-linking treatment to the region of the cornea. During the application of the corneal cross-linking treatment, the method also comprises acquiring a temporal OCT interferogram at each OCT measurement location, generating temporal complex OCT data based on the temporal OCT interferogram, determining biomechanical data based on the temporal complex OCT data, and adjusting the corneal cross-linking treatment based on the biomechanical data.
A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.
A system for performing ophthalmic treatments includes a handpiece configured to be held by a hand of a surgeon. An end effector is mounted to the handpiece and configured to manipulate tissue of a patient, such tissues of the eye when performing an ophthalmic treatment. The system includes a motion sensor configured to sense movement of the handpiece and one or more stabilizing actuators configured to stabilize movement of the handpiece in response to movement of the hand of the surgeon. A controller is coupled to the motion sensor and the one or more stabilizing actuators and is configured to instruct the one or more stabilizing actuators to compensate for motion detected by the motion sensor. The controller may include a high-pass filer with the output of the high-pass filter used to control the stabilizing actuators. The parameters of the high pass filter may be adjusted throughout an ophthalmic treatment.
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
Described herein is a system for surgical procedures. The system can include a tray and a wireless remote. The tray may include a magnetically attractive layer. The wireless remote is configured to control one or more aspects associated with operations of a surgical console and includes one or more magnets configured to magnetically interact with the magnetically attractive layer and couple the wireless remote to the tray.
Systems and methods for measuring corneal biomechanical properties are provided. In certain embodiments, a method comprises determining a plurality of optical coherence tomography (OCT) measurement locations in a region of a cornea; for each OCT measurement location: applying a mechanical excitation to the cornea at the OCT measurement location, and measuring a response of the cornea to the mechanical excitation by acquiring temporal OCT data at the OCT measurement location; generating temporal deformation data for the region of the cornea based on the temporal OCT data at each OCT measurement location; and generating biomechanical data for the region of the cornea based on the temporal deformation data.
A system and method for corneal cross-linking with real-time monitoring are provided. The method comprises determining a plurality of measurement locations in a region of a cornea, and applying a corneal cross-linking treatment to the region of the cornea. During the application of the corneal cross-linking treatment, the method also comprises acquiring a temporal OCT interferogram at each OCT measurement location, generating temporal complex OCT data based on the temporal OCT interferogram, determining biomechanical data based on the temporal complex OCT data, and adjusting the corneal cross-linking treatment based on the biomechanical data.
A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.
A system for performing ophthalmic treatments includes a surgical microscope configured to capture surface images of an eye of a patient and an imaging device mounted to the surgical microscope and configured to capture section images of the eye of the patient. A controller is coupled to the surgical microscope and the imaging device, the controller configured to receive the surface images and section images and provide feedback facilitating performance of the ophthalmic treatments based on the section images and the surface images. Feedback may relate to avoiding bag rupture during phacoemulsification, safely performing retinal membrane peeling, placing an IOL, treating glaucoma, or performing other ophthalmic treatments.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/16 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring intraocular pressure, e.g. tonometers
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A system for performing ophthalmic treatments includes a surgical microscope configured to capture surface images of an eye of a patient and an imaging device mounted to the surgical microscope and configured to capture section images of the eye of the patient. A controller is coupled to the surgical microscope and the imaging device, the controller configured to receive the surface images and section images and provide feedback facilitating performance of the ophthalmic treatments based on the section images and the surface images. Feedback may relate to avoiding bag rupture during phacoemulsification, safely performing retinal membrane peeling, placing an IOL, treating glaucoma, or performing other ophthalmic treatments.
An ophthalmic assembly includes a frame, flange, and light emitter. The frame supports an optical lens. A first end of the flange is connected to the frame. A second end of the flange rests on a pars plana region of the sclera of a patient's eye. The light emitter is connected to the flange proximate the second end to direct light into a vitreous cavity of the patient's eye. This occurs through the sclera at the pars plana region and uniformly illuminates the vitreous. A transscleral illumination system includes the ophthalmic assembly and a processor in communication with the light emitter. A setting of the light emitter may be controllable via the processor, e.g., in response to a user input signal.
