A wide angle viewing system (WAVS) includes a microscope having a microscope light source, a front lens assembly connected to the microscope that is moveable between engaged and disengaged positions, and a processor. The processor performs a method during which the processor determines a current position of the front lens assembly as one of the engaged or disengaged position and executes an illumination switching control action in response to the current position. The control action includes turning off the microscope light source and turning on the illumination tool when the front lens assembly is in the engaged position. The control action also includes turning on the microscope light source and turning off the illumination tool when the front lens assembly is in the disengaged position.
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
2.
ARTIFICIAL INTELLIGENCE SENTINEL FOR SURGICAL PLANNING
A computer-implemented method of machine learning based surgical planning optimization. Embodiments include receiving, by an artificial intelligence agent, a request related to a surgical procedure that is to be performed on a patient. Embodiments include retrieving medical data that is related to the request from one or more source devices. Embodiments include generating, using a machine learning model, content related to the surgical procedure that is to be performed on the patient based on the request and the medical data, wherein the content comprises a set of relevant data points about the patient with respect to the surgical procedure or an indication of an issue related to a surgical plan. Embodiments include providing the content via an output device.
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
3.
WIDE ANGLE VIEWING SYSTEM WITH OPHTHALMIC ILLUMINATION SWITCHING FUNCTIONALITY
A wide angle viewing system (WAVS) includes a microscope having a microscope light source, a front lens assembly connected to the microscope that is moveable between engaged and disengaged positions, and a processor. The processor performs a method during which the processor determines a current position of the front lens assembly as one of the engaged or disengaged position and executes an illumination switching control action in response to the current position. The control action includes turning off the microscope light source and turning on the illumination tool when the front lens assembly is in the engaged position. The control action also includes turning on the microscope light source and turning off the illumination tool when the front lens assembly is in the disengaged position.
The present disclosure relates to operations that include identifying, based on an optical imaging result corresponding to a tissue, a non-uniform layer that is disposed in an optical measurement path corresponding to the optical imaging result. The operations may also include performing one or more adjustment operations with respect to the optical imaging result based on identification of the non-uniform layer.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p. ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersectionsAnalyse de connectivité, p. ex. de composantes connectées
A computer-implemented method of machine learning based surgical planning optimization. Embodiments include receiving, by an artificial intelligence agent, a request related to a surgical procedure that is to be performed on a patient. Embodiments include retrieving medical data that is related to the request from one or more source devices. Embodiments include generating, using a machine learning model, content related to the surgical procedure that is to be performed on the patient based on the request and the medical data, wherein the content comprises a set of relevant data points about the patient with respect to the surgical procedure or an indication of an issue related to a surgical plan. Embodiments include providing the content via an output device.
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
6.
DEVICES AND METHODS FOR IMPROVED FOLLOWABILITY IN LASER-BASED OCULAR PROCEDURES
Devices and methods are disclosed for improved followability in laser-based ocular procedures. In some embodiments, an ophthalmic instrument comprises a projection located at the distal end of the shaft or cannula, the projection having a distal surface in proximity to the distal end of the optical fiber, the distal surface adapted to be positioned facing the treatment area during use of the ophthalmic instrument. An example method includes delivering laser energy through an optical fiber to the treatment area, wherein the distal surface of the projection inhibits bubbles formed during the procedure from moving distally away from the distal end of the ophthalmic instrument.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
A method of delivering a pharmaceutical composition to Schlemm’s canal of an eye is disclosed. The method may comprise inserting a drug delivery device in conjunction with a microstent into Schlemm’s canal. The drug delivery device may comprise a bioerodable polymer and a pharmaceutical composition, and the drug delivery device may be configured to erode over time and to elute the pharmaceutical composition into aqueous humor within Schlemm’s canal as it erodes.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 2/94 - Stents conservant leur forme, c.-à-d. non déformables, après mise en place à l’endroit voulu
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
The present disclosure relates to an intraocular lens injector that includes an injector body and a nozzle coupled to the injector body to deliver an IOL to a surgical site. The injector body may include a compartment to house the IOL and receive a moveable plunger. A folding chamber may be coupled to the compartment. The folding chamber may be shaped to fold opposing portions of the IOL as the moveable plunger advances the IOL through the folding chamber to form an optic fold and to offset the optic fold from a vertical plane centered within and extending through the folding chamber.
The present disclosure relates to an intraocular lens injector that includes an injector body and a nozzle coupled to the injector body to deliver an IOL to a surgical site. The injector body may include a compartment to house the IOL and receive a moveable plunger. A folding chamber may be coupled to the compartment. The folding chamber may be shaped to fold opposing portions of the IOL as the moveable plunger advances the IOL through the folding chamber to form an optic fold and to offset the optic fold from a vertical plane centered within and extending through the folding chamber.
Disclosed are adjustable intraocular lenses and methods of adjusting intraocular lenses post-operatively. In one embodiment, an adjustable accommodating intraocular lens comprises an optic portion and at least one haptic. At least part of the haptic can be made in part of a composite material comprising an energy absorbing constituent and a plurality of shrinkable and/or burstable microspheres. At least one of a base power of the optic portion can be configured to change in response to an external energy directed at the composite material.
A laser system for use in various surgical procedures. A system may include a laser source, an arm having a free-space optical path coupled to the laser source, and a cable having a waveguide coupled to the free-space optical path.
A61B 18/20 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers
A61B 18/22 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers le faisceau étant dirigé le long, ou à l'intérieur d'un conduit flexible, p. ex. d'une fibre optiquePièces à main à cet effet
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
Embodiments disclosed herein provide a cradle. The cradle includes a housing and one or more magnets disposed in the housing. The housing has an aperture therethrough for holding a remote that controls one or more aspects associated with operations of a surgical console. The one or more magnets are configured to magnetically interact with a magnetically attractive layer within a tray of the surgical console, and movably couple the housing to the tray. The housing further includes a first casing having a first surface configured to engage with the tray, and a second casing coupled to the first casing, the second casing having a second surface that faces an opposite direction of the first surface.
An inspection glass holder is suggested for carrying a plurality of inspection glasses. The holder comprises a QR code that is commonly allocated to the inspection glasses arranged thereon. Prior to separating the foil from the blister, the data printed on the foil including the individual blister code is automatically read and is allocated to the QR code of the holder in the same sequence. Thereafter, the foil is separated from the shells and the lenses are transferred from the shells of the blister packages to the inspection glasses in the same sequence. The parameters of the lenses measured in the inspection glasses are correctly associated to the data read from the foil which are all allocated to the same QR code of the holder.
In certain embodiments, a surgical laser system includes a laser probe and a laser subsystem. The laser probe is configured to emit a treatment light beam and an illumination light beam and receive a back-reflected illumination light beam. The laser subsystem includes a pulsed laser source, a continuous wave laser source, an optical sensor, and a controller. The pulsed laser source is configured to generate the treatment light beam in response to a control signal. The continuous wave laser source is configured to generate the illumination light beam. The optical sensor is configured to generate a data signal in response to receiving the back-reflected illumination light beam from the laser probe. The controller is configured to generate the control signal for the pulsed laser source, generate a restored back-reflected pulse based on back-reflected pulses in the data signal, and present the restored back-reflected pulse on a display.
Embodiments disclosed herein provide a connector for an ophthalmic surgical device. The connector includes a housing, an optical fiber, a ferrule body, a protective tube, and a ferrule. The housing is configured to be gripped by a user for coupling to a surgical console. The optical fiber is disposed within the housing, the ferrule body is disposed around at least a portion of the optical fiber, and the protective tube is disposed within the ferrule body. The ferrule is coupled to the ferrule body and the protective tube. The ferrule defines a cavity at a proximal end of the ferrule, and the optical fiber is at least partially disposed within the cavity.
G02B 6/38 - Moyens de couplage mécaniques ayant des moyens d'assemblage fibre à fibre
A61B 18/22 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers le faisceau étant dirigé le long, ou à l'intérieur d'un conduit flexible, p. ex. d'une fibre optiquePièces à main à cet effet
G02B 6/42 - Couplage de guides de lumière avec des éléments opto-électroniques
In certain embodiments, an illuminator system provides illumination for a patient interface. The illuminator system includes input bundles, a fiber randomizer, and output bundles. The input bundles include a first input bundle and a second input bundle. The first input bundle includes first fibers, where each first fiber transmits a first light from a first light source. The second input bundle includes second fibers, where each second fiber transmits a second light from a second light source. The fiber randomizer receives the first fibers from the first input bundle, receives the second fibers from the second input bundle, and distributes the first and the second fibers among subsets of output fibers. Each subset of output fibers has at least one first fiber and at least one second fiber. Each output bundle includes a subset of output fibers and provides the first light and the second light to the patient interface.
An apparatus for the automated separation of a strip of primary packages comprises a plurality of vacuum grippers arranged along a row, each vacuum gripper comprising a gripping surface for contacting the respective sealing foil portion sealed to a dedicated primary packaging shell of one primary package of the strip. Adjacently arranged vacuum grippers are rotatable relative to one another around a rotation axis. The apparatus further comprises a rotary drive unit for rotating the plurality of vacuum grippers with respect to one another between an inplane arrangement, in which the gripping surfaces of all vacuum grippers are arranged in a common plane, and a twisted arrangement, in which the gripping surfaces of adjacently arranged vacuum grippers are arranged rotated relative to one another around the rotation axis and include a rotational angle (α) in the range of 60 degrees to 120 degrees.
B65B 61/12 - Dispositifs accessoires, non prévus ailleurs, opérant sur feuilles, flans, bandes, attaches, réceptacles ou paquets pour découper les bandes ou pour séparer les paquets joints en déchirant le long des perforations ou des lignes de moindre résistance
B65B 25/00 - Emballage d'autres objets présentant des problèmes particuliers
In certain embodiments, a surgical laser system includes a laser probe and a laser subsystem. The laser probe is configured to emit a treatment light beam and an illumination light beam and receive a back-reflected illumination light beam. The laser subsystem includes a pulsed laser source, a continuous wave laser source, an optical sensor, and a controller. The pulsed laser source is configured to generate the treatment light beam in response to a control signal. The continuous wave laser source is configured to generate the illumination light beam. The optical sensor is configured to generate a data signal in response to receiving the back-reflected illumination light beam from the laser probe. The controller is configured to generate the control signal for the pulsed laser source, generate a restored back-reflected pulse based on back-reflected pulses in the data signal, and present the restored back-reflected pulse on a display.
In certain embodiments, an illuminator system provides illumination for a patient interface. The illuminator system includes input bundles, a fiber randomizer, and output bundles. The input bundles include a first input bundle and a second input bundle. The first input bundle includes first fibers, where each first fiber transmits a first light from a first light source. The second input bundle includes second fibers, where each second fiber transmits a second light from a second light source. The fiber randomizer receives the first fibers from the first input bundle, receives the second fibers from the second input bundle, and distributes the first and the second fibers among subsets of output fibers. Each subset of output fibers has at least one first fiber and at least one second fiber. Each output bundle includes a subset of output fibers and provides the first light and the second light to the patient interface.
An apparatus for the automated separation of a strip of primary packages comprises a plurality of vacuum grippers arranged along a row, each vacuum gripper comprising a gripping surface for contacting the respective sealing foil portion sealed to a dedicated primary packaging shell of one primary package of the strip. Adjacently arranged vacuum grippers are rotatable relative to one another around a rotation axis. The apparatus further comprises a rotary drive unit for rotating the plurality of vacuum grippers with respect to one another between an inplane arrangement, in which the gripping surfaces of all vacuum grippers are arranged in a common plane, and a twisted arrangement, in which the gripping surfaces of adjacently arranged vacuum grippers are arranged rotated relative to one another around the rotation axis and include a rotational angle (α) in the range of 60 degrees to 120 degrees.
B65B 61/12 - Dispositifs accessoires, non prévus ailleurs, opérant sur feuilles, flans, bandes, attaches, réceptacles ou paquets pour découper les bandes ou pour séparer les paquets joints en déchirant le long des perforations ou des lignes de moindre résistance
B65D 75/36 - Objets ou matériaux enveloppés entre deux feuilles ou flans opposés à bords réunis, p. ex. par adhésifs à pression, pliage, thermosoudage ou soudage une ou les deux feuilles ou flans étant renfoncés pour épouser la forme du contenu une feuille ou un flan étant renfoncés et l'autre fait d'une feuille plate relativement rigide, p. ex. empaquetage pour ampoules
A laser system for use in various surgical procedures. A system may include a laser source, an arm having a free-space optical path coupled to the laser source, and a cable having a waveguide coupled to the free-space optical path.
An inspection glass holder is suggested for carrying a plurality of inspection glasses. The holder comprises a QR code that is commonly allocated to the inspection glasses arranged thereon. Prior to separating the foil from the blister, the data printed on the foil including the individual blister code is automatically read and is allocated to the QR code of the holder in the same sequence. Thereafter, the foil is separated from the shells and the lenses are transferred from the shells of the blister packages to the inspection glasses in the same sequence. The parameters of the lenses measured in the inspection glasses are correctly associated to the data read from the foil which are all allocated to the same QR code of the holder.
B65B 57/14 - Dispositifs de commande automatique, de vérification, d'alarme ou de sécurité sensibles à l'absence, à la présence, à l'alimentation anormale ou au mauvais positionnement des objets ou matériaux à emballer et dont le fonctionnement commande ou arrête l'alimentation des objets ou matériaux à emballer
B65B 25/00 - Emballage d'autres objets présentant des problèmes particuliers
25.
ACCOMMODATING INTRAOCULAR LENSES AND METHODS OF MANUFACTURING
An intraocular lens is disclosed that includes an optic body with a projection extending radially outwards from a peripheral surface of the optic body. The projection comprises a haptic contact surface facing radially outward, wherein the entire haptic contact surface is a flat surface. A haptic having a free distal end and a proximal portion is secured to the projection along the haptic contact surface, wherein the projection and the proximal portion interface at a butt joint without the haptic extending into the projection and without the projection extending into the haptic. The haptic also includes a haptic fluid chamber.
G02B 3/04 - Lentilles simples ou composées à surfaces non sphériques à surfaces continues engendrées par une rotation autour d'un axe, mais s'écartant d'une véritable sphère
G02B 3/12 - Lentilles remplies d'un fluide ou à l'intérieur desquelles le vide a été fait
26.
METHODS AND SYSTEMS FOR ENHANCED OPHTHALMIC VISUALIZATION
In certain embodiments, a system, a computer-implemented method, and computer-readable medium are disclosed for enhanced ophthalmic visualization. A plurality of images corresponding to different portions of the electromagnetic spectrum are obtained and combined, such as by pixel-wise subtraction to obtain a combined image. The images may be weighted with weights selected to enhance visualization of features, such as layers of the retina or features corresponding to pathologies. The combined image may be processed, such as by a machine learning model, to extract features.
In general, embodiments of the present disclosure relate to contact lenses configured to prevent or slow the development of myopia in children. In particular, embodiments of the present disclosure relate to contact lenses that produce de-focused blue light. In at least some embodiments, a contact lens for treating myopia progression is provided. The contact lens includes a bulk silicone hydrogel material and a monomeric optical brightener disposed throughout the bulk silicone hydrogel material. The bulk silicone hydrogel material includes repeating units of at least one hydrophilic vinylic monomer and repeating units of at least one silicone-containing vinylic monomer, at least one polysiloxane vinylic crosslinker or combinations thereof.
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
28.
TEAR FILM STABILITY ASSESSMENT WITH INTEGRATED GRAPHICAL REPRESENTATION
A method of assessing tear film stability in an ocular surface includes obtaining tear film breakup time data and blink time series for the ocular surface, via one or more imaging assemblies. The method includes converting the tear film breakup time data to a tear film breakup map represented as a polar data array, via a controller, such that respective elements in the polar data array represent a local tear film breakup time at respective radial and angular locations. The blink time series is converted to an interblink interval map such that respective elements in the interblink interval map represent an interblink time interval at different blink completeness levels. The tear film breakup map is integrated with the interblink interval map to generate a tear film stability map. The method includes directing a remedial action when an enabling condition related to the tear film stability map is met.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
29.
METROLOGY TOOL FOR OPHTHALMIC DEVICE PERFORMANCE ASSESSMENT
A fabrication fixture assembly includes a base having at least one projection and a latitudinal positioning portion having at least one rail defining an arcuate slot extending therethrough. The arcuate slot follows a radius of curvature and the at least one projection is coupled to the latitudinal positioning portion through the at least one rail. The assembly also includes a rotational positioning portion attached to the at least one rail and moveable with the latitudinal positioning portion. The rotational positioning portion is configured to accept a metrology tool and selectively position the metrology tool in one of a plurality of rotational positions.
An anchor copolymer having repeating units from: (a) at least one arylboronic acid vinylic monomer and (b) at least one carboxyl vinylic monomer can be used to at or near a surface of a soft hydrogel contact lens and used to directly, or indirectly bind an active agent to the soft contact lens. In some aspects, a polyphenol can be bound to the anchor copolymer of the soft contact lens and a wetting agent bound to the polyphenol. Such a soft hydrogel contact lens can be used to manage dry eye, for example.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/736 - Glucomannanes ou galactomannanes, p. ex. gomme de caroube, gomme de guar
C08L 5/00 - Compositions contenant des polysaccharides ou leurs dérivés non prévus dans les groupes ou
C08L 71/10 - Polyéthers dérivés de composés hydroxylés ou de leurs dérivés métalliques de phénols
C08F 230/06 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et contenant du phosphore, du sélénium, du tellure ou un métal contenant un métal contenant du bore
C08F 220/06 - Acide acryliqueAcide méthacryliqueLeurs sels métalliques ou leurs sels d'ammonium
A fabrication fixture assembly includes a base having at least one projection and a latitudinal positioning portion having at least one rail defining an arcuate slot extending therethrough. The arcuate slot follows a radius of curvature and the at least one projection is coupled to the latitudinal positioning portion through the at least one rail. The assembly also includes a rotational positioning portion attached to the at least one rail and moveable with the latitudinal positioning portion. The rotational positioning portion is configured to accept a metrology tool and selectively position the metrology tool in one of a plurality of rotational positions.
G03F 7/00 - Production par voie photomécanique, p. ex. photolithographique, de surfaces texturées, p. ex. surfaces impriméesMatériaux à cet effet, p. ex. comportant des photoréservesAppareillages spécialement adaptés à cet effet
33.
AUTOMATIC SEGMENTATION OF ANTERIOR SEGMENT OF AN EYE IN OPTICAL COHERENCE TOMOGRAPHY IMAGES
Provided herein are techniques for automatically segmenting anterior segment of an eye in an optical coherence tomography (OCT) image. A method includes receiving an OCT image of an eye; cropping, based on one or more structures of the eye in the OCT image, the OCT image of the eye into one or more sub-images corresponding to the one or more structures; for each of the one or more sub-images of the OCT image of the eye: generating a background seed and a foreground seed of the sub-image; generating, based on the background and the foreground seeds, and an image segmentation model, a mask for a structure of the one or more structures of the eye included in the sub-image; generating, based on the mask for the structure, one or more contours of the structure included in the sub-image; and displaying the one or more contours on the sub-image.
An eye depressor with a light for directing through a sclera. The depressor may removably accommodate a light instrument that might be used to illuminate an area in an eye during an eye surgery. The coupling of the light instrument to the depressor during the procedure may reduce the number of hands required in carrying out the surgery. This may be of particular benefit for eye surgery where limited surgical space is available.
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
Adjusting illumination sources based on stages of ophthalmic surgery is described. An ophthalmic surgical system may include a first illumination source configured to produce a first light beam for illuminating a surgical region of an eye, upon which an ophthalmic surgical procedure is being performed, from a first direction, and a second illumination source configured to produce a second light beam for illuminating the surgical region of the eye from a second direction. The ophthalmic surgical system may further include a surgical stage-based illumination module implemented in a non-transitory computer-readable storage medium and configured to determine, in real-time, a stage of the ophthalmic surgical procedure based on a detected trigger event. The surgical stage-based illumination module may be further configured to output, in real-time, instructions to adjust at least one of the first illumination source or the second illumination source based on the stage of the ophthalmic surgical procedure.
The present disclosure relates to a vacuum system for an ophthalmic surgical system. The vacuum system includes a vacuum accumulator, a patient interface, and a vacuum generation system. The patient interface is pneumatically coupled to the vacuum accumulator and engageable with patient tissue responsive to application of vacuum pressure from the vacuum accumulator through the patient interface to the patient tissue. The vacuum generation system is coupled to the vacuum accumulator and includes multiple diaphragm gas pump heads and one or more solenoid valves. The multiple diaphragm gas pump heads include at least a first head and a second head. The one or more solenoid valves are coupled to the first and second heads and are configured to selectively pneumatically couple the first head and the second head in parallel or series. The system may further include a pressure accumulator and may be selectively switched between vacuum or pressure accumulation.
Hydrogel contact lenses for release of active agents can include a hydrogel polymeric matrix having dispersed therein nanohydrogels loaded with active agent. The nanohydrogels can be responsive to pH and be composed of a copolymer prepared from one or more hydrophilic vinylic monomers, and one or more vinylic crosslinkers and/or vinylic crosslinker agents that include carboxylic acids and ether linkages.
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
B29D 11/00 - Fabrication d'éléments optiques, p. ex. lentilles ou prismes
An apparatus for eye surgery, which may comprise a tube, a base having a plurality of base teeth coupled to the base, and a blade. The blade can be configured to move around an axis of rotation relative to the base teeth parallel to a shearing plane. The shearing plane can be orthogonal to the axis of rotation, and oriented at an obtuse angle relative to a longitudinal axis of the tube. A driver can be configured to oscillate the blade parallel to the shearing plane. The base may comprise a surface configured to interface with a retina and may have a curved profile. The base profile may have a center of curvature that is coincident with the axis of rotation. Some embodiments of the base profile may be characterized as an arc, circular arc, or semicircle.
A computer-implemented method of machine learning based medical treatment optimization. Embodiments include receiving, by an artificial intelligence (AI) agent, a request related to treating a patient. Embodiments include retrieving medical data that is related to the request from one or more source devices, whereint he medical data includes multiple data modalities. Embodiments include generating, using a multimodal machine learning model, response content related to treating the patient based on the request and the medical data. Embodiments include providing the response content via an output device.
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
41.
OPTICAL BRIGHTENERS IN MYOPIA CONTROL CONTACT LENSES
In general, embodiments of the present disclosure relate to contact lenses configured to prevent or slow the development of myopia in children. In particular, embodiments of the present disclosure relate to contact lenses that produce de-focused blue light. In at least some embodiments, a contact lens for treating myopia progression is provided. The contact lens includes a bulk silicone hydrogel material and a monomeric optical brightener disposed throughout the bulk silicone hydrogel material. The bulk silicone hydrogel material includes repeating units of at least one hydrophilic vinylic monomer and repeating units of at least one silicone-containing vinylic monomer, at least one polysiloxane vinylic crosslinker or combinations thereof.
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
A method of assessing tear film stability in an ocular surface includes obtaining tear film breakup time data and blink time series for the ocular surface, via one or more imaging assemblies. The method includes converting the tear film breakup time data to a tear film breakup map represented as a polar data array, via a controller, such that respective elements in the polar data array represent a local tear film breakup time at respective radial and angular locations. The blink time series is converted to an interblink interval map such that respective elements in the interblink interval map represent an interblink time interval at different blink completeness levels. The tear film breakup map is integrated with the interblink interval map to generate a tear film stability map. The method includes directing a remedial action when an enabling condition related to the tear film stability map is met.
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
An anchor copolymer having repeating units from: (a) at least one arylboronic acid vinylic monomer and (b) at least one carboxyl vinylic monomer can be used to at or near a surface of a soft hydrogel contact lens and used to directly, or indirectly bind an active agent to the soft contact lens. In some aspects, a polyphenol can be bound to the anchor copolymer of the soft contact lens and a wetting agent bound to the polyphenol. Such a soft hydrogel contact lens can be used to manage dry eye, for example.
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
C08L 33/02 - Homopolymères ou copolymères des acidesLeurs sels métalliques ou d'ammonium
44.
MONITORING UTILIZATION OF REUSABLE SURGICAL DEVICES
Certain aspects of the present disclosure provide systems and methods for monitoring usage of reusable surgical devices. In certain embodiments, an apparatus includes a housing defining an external reader surface, and a wireless reader comprising an antenna disposed within the housing. Within a bandwidth of the antenna, a majority of a radiation pattern of the antenna extends through the external reader surface. The apparatus further includes a reflector disposed near the antenna opposite the external reader surface. The reflector is configured to reorient a portion of the radiation pattern as a reflected portion that extends through the external reader surface.
A61B 90/98 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes utilisant des moyens électromagnétiques, p. ex. transpondeurs
H01Q 19/12 - Combinaisons d'éléments actifs primaires d'antennes avec des dispositifs secondaires, p. ex. avec des dispositifs quasi optiques, pour donner à une antenne une caractéristique directionnelle désirée utilisant des surfaces réfléchissantes où les surfaces sont concaves
45.
SYSTEMS AND METHODS FOR CONTROLLING LASER TRANSMISSION DURING OPHTHALMIC PROCEDURES
Embodiments disclosed herein provide a system for controlling laser transmission during an ophthalmic procedure. The system includes first and second laser sources, an optical fiber, and a signal detector. The first and second laser sources are configured to respectively generate first and second laser beams. The optical fiber is configured to receive the first and second laser beams from the first and second laser sources, transmit the first and second laser beams from a distal end of the optical fiber, receive a reflected portion of the second laser beam, and direct the reflected portion to the signal detector. The signal detector is configured to receive the reflected portion from the optical fiber, and generate a signal detector output based on the reflected portion. The signal detector output is indicative of a presence or an absence of a bubble or vapor at the distal end of the optical fiber.
A61B 18/22 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p. ex. de micro-ondes en utilisant des lasers le faisceau étant dirigé le long, ou à l'intérieur d'un conduit flexible, p. ex. d'une fibre optiquePièces à main à cet effet
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
An apparatus for eye surgery, which may comprise a tube, a base having a plurality of base teeth coupled to the base, and a blade. The blade can be configured to move around an axis of rotation relative to the base teeth parallel to a shearing plane. The shearing plane can be orthogonal to the axis of rotation, and oriented at an obtuse angle relative to a longitudinal axis of the tube. A driver can be configured to oscillate the blade parallel to the shearing plane. The base may comprise a surface configured to interface with a retina and may have a curved profile. The base profile may have a center of curvature that is coincident with the axis of rotation. Some embodiments of the base profile may be characterized as an arc, circular arc, or semicircle.
An intraocular pressure sensor system (100, 300) and method (200) are described. The intraocular pressure sensor system (100, 300) includes a surface acoustic wave modifier (104, 308) and at least one signal receiver (102, 302). The surface acoustic wave modifier modifies an initial surface acoustic wave signal based on intraocular pressure of an eye of a patient to produce a modified surface acoustic wave signal. The at least one signal receiver receives a first signal and produces the initial surface acoustic wave signal based upon the first signal. The at least one signal receiver also receives the modified surface acoustic wave signal and produces a second signal based upon the modified surface acoustic wave signal. The second signal is comparable to the first signal to determine a value indicative of the intraocular pressure of the eye.
A61B 3/16 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p. ex. tonomètres
48.
ARTIFICIAL INTELLIGENCE AGENT FOR OPERATING ROOMS AND SURGERY
A computer-implemented method of machine learning based medical treatment optimization. Embodiments include receiving, by an artificial intelligence (AI) agent, a request related to treating a patient. Embodiments include retrieving medical data that is related to the request from one or more source devices, whereint he medical data includes multiple data modalities. Embodiments include generating, using a multimodal machine learning model, response content related to treating the patient based on the request and the medical data. Embodiments include providing the response content via an output device.
G16H 20/00 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
In certain embodiments, a system includes a vitrectomy handpiece and a pneumatic assembly coupled to the vitrectomy handpiece. The vitrectomy handpiece includes a cutting assembly, and a diaphragm disposed in a drive chamber and coupled to the cutting assembly. The pneumatic assembly includes an airflow controlling member and an actuating assembly. The airflow controlling member is configured to direct air to the drive chamber to move the diaphragm, thereby actuating the cutting assembly. The actuating assembly is configured to actuate the airflow controlling member.
A drug delivery device includes a conveyor and a docking assembly movable by the conveyor to a plurality of patient stations. The docking assembly includes one or more imaging devices configured to have an eye of the patient in a field of view thereof. The docking assembly includes an injection assembly and a staging assembly including one or more actuators and configured to position the injection assembly relative to the eye of the patient. A controller is configured to receive one or more images from the one or more imaging devices; detect anatomy of the eye of the patient in the one or more images; and activate the one or more actuators to drive a needle mounted to the injection assembly into a placement location on the eye of the patient according to the location of the anatomy. A loader loads injection assemblies into the docking assembly.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61G 15/12 - Appuis qui leur sont spécialement adaptés, p. ex. pour la tête ou les pieds
A61M 5/42 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras avec des moyens pour insensibiliser la peau, pour soulever la peau en vue de faciliter la piqûre ou pour localiser le point du corps où la piqûre doit être effectuée
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61B 34/32 - Robots chirurgicaux opérant de façon autonome
One or more images of an eye of a patient having an implanted IOL are received. The one or more images are captured using one or more imaging devices having one or more imaging modalities. A computing device determines misalignment of the IOL according to the one or more images and processes the misalignment using a predictive model to obtain an improvement probability. The computing device outputs an intervention recommendation according to the improvement probability. The intervention recommendation may be the result of cost/benefit analysis of the improvement probability.
Embodiments disclosed herein provide an ophthalmic illumination device. The ophthalmic illumination device includes a first optical fiber having a proximal end and a distal end, and a second optical fiber having a proximal end and a distal end. The proximal end of the first optical fiber is coupled to a light source that provides an illumination light, and the distal end of the first optical fiber is disposed within a first ferrule. The proximal end of the second optical fiber is disposed within a second ferrule, and the distal end of the second optical fiber is configured to transmit the illumination light received from the first optical fiber into an interior portion of a patient's eye. The first ferrule is disposed against the second ferrule to couple the distal end of the first optical fiber with the proximal end of the second optical fiber.
In certain embodiments, a system includes a vitrectomy handpiece and a pneumatic assembly coupled to the vitrectomy handpiece. The vitrectomy handpiece includes a cutting assembly, and a diaphragm disposed in a drive chamber and coupled to the cutting assembly. The pneumatic assembly includes an airflow controlling member and an actuating assembly. The airflow controlling member is configured to direct air to the drive chamber to move the diaphragm, thereby actuating the cutting assembly. The actuating assembly is configured to actuate the airflow controlling member.
A system includes an ophthalmic microscope configured to capture video of an ophthalmic treatment. A computer system is coupled to the ophthalmic microscope and is configured to: receive a first image from the ophthalmic microscope for a first wavelength band having a first width of less than 20 nanometers; receive a second image from the ophthalmic microscope for a second wavelength band having a second width of less than 20 nanometers; generate a vessel map of a retina of the eye of the patient according to the first image and the second image, the vessel map including representations of blood vessels of the retina; and display the vessel map on a display device. The computer system may further receive a reference image for an isosbestic wavelength band of oxygenated and de-oxygenated hemoglobin and generate the vessel map according to the reference image.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
Intra-ocular lens (IOL) data describing an IOL model is processed using a machine learning model to obtain a selected calculator of a plurality of calculators that may be used to estimate the post-operative refractive error of the IOL model. The IOL data may be processed with patient data, such as eye measurements and patient history. Eye measurements may include anterior chamber depth (ACD) and white-to-white (WTW) distance. Patient history may include whether an eye has undergone past refractive error correction surgery. The selected calculator may be used to calculate a post-operative refractive error to guide selection of an IOL.
A retina visualization system includes a laser device operable for outputting a primary laser beam, the laser device including a red, green, blue (RGB) diode array and an infrared (IR) diode, along with a stereo, confocal, biaxial microelectromechanical system (MEMS) scanning system. The scanning system receives the primary laser beam and outputs a scanning laser toward an eye along a visualization path. A Shack Hartmann wavefront sensor proximate the eye senses wavefront distortion in light reflected from the eye. A wavefront control device corrects the wavefront distortion in response to a control signal. A stereo pair of avalanche photodiode (APD) detectors detects light and generates an electronic signal in response thereto. An electronic control unit (ECU) transmits the control signal the wavefront control device to cause the wavefront control device to correct the wavefront distortion into a corrected wavefront, with corrected images displayed via a stereo display device.
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
In certain embodiments, an ophthalmic injection robot includes a frame, a robotic arm, a docking assembly, and a control system. The frame includes a patient support and positioning cameras. The docking assembly is coupled to the robotic arm, and includes fine adjustment cameras, and a staging assembly including fine adjustment actuators, a needle extension actuator, and a needle assembly including a needle. The control system includes a memory and a processor configured to receive the fine adjustment image data generated by fine adjustment cameras, process the fine adjustment image data to generate a blood vessel map of an eye of a patient, select an injection site on the eye of the patient based on the blood vessel map, and control the fine adjustment actuators to position the needle above the selected injection site for target-confirmed injection of a drug through the needle and into the eye of the patient.
A61B 34/32 - Robots chirurgicaux opérant de façon autonome
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61M 5/42 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaireAccessoires à cet effet, p. ex. dispositifs de remplissage ou de nettoyage, appuis-bras avec des moyens pour insensibiliser la peau, pour soulever la peau en vue de faciliter la piqûre ou pour localiser le point du corps où la piqûre doit être effectuée
58.
CONTROLLED RELEASE OF DRY EYE RELIEF AGENT FROM CONTACT LENS
Embodiments of the present disclosure generally relate to methods and processes for forming an ophthalmic product, such as contact lenses. More specifically, embodiments described herein relate to the production of contact lenses having a water-soluble phospholipid polymer disposed thereon, which may be released therefrom as an ophthalmic comfort agent during use of the contact lens. In some embodiments, a contact lens includes a bulk layer having a crosslinked polymeric material, and a poly(vinyl alcohol) (PVA) layer disposed on the bulk layer. The contact lens further includes a water-soluble phospholipid polymer disposed on the PVA layer. The water-soluble phospholipid polymer includes a plurality of phosphorylcholine units and a plurality of arylborono units.
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
59.
EMBEDDED CONTACT LENSES WITH SURFACE AND ASTIGMATISM MASKING
In general, embodiments of the present disclosure relate to pigment containing contact lenses (100), such as colored contact lenses. In particular, embodiments of the present disclosure relate to a hybrid hard-soft silicone hydrogel contact lens (100). In at least some embodiments, a method for forming a contact lens (100) is provided. The method includes printing a pigmented layer (106) on a lens mold including an optic zone (207) and curing the pigmented layer (106) with ultraviolet (UV) light. The pigmented layer (106) is printed outside an outer boundary of the optic zone (207) of the lens mold. The method further includes forming an insert lens layer (104), the insert lens layer disposed on the cured pigmented layer (106), curing the insert lens layer (104) to form an insert lens (310) having a modulus of greater than about 2 MPa, suspending the insert lens (310) in a lens-forming material (108) and curing the lens-forming material (108) to form a lens body (100).
Certain aspects of the present disclosure provide systems and methods for monitoring usage of reusable surgical devices. In certain embodiments, an apparatus includes a housing defining an external reader surface, and a wireless reader comprising an antenna disposed within the housing. Within a bandwidth of the antenna, a majority of a radiation pattern of the antenna extends through the external reader surface. The apparatus further includes a reflector disposed near the antenna opposite the external reader surface. The reflector is configured to reorient a portion of the radiation pattern as a reflected portion that extends through the external reader surface.
A61B 90/98 - Moyens d’identification pour les patients ou les instruments, p. ex. étiquettes utilisant des moyens électromagnétiques, p. ex. transpondeurs
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
61.
SYSTEMS AND METHODS FOR CONTROLLING LASER TRANSMISSION DURING OPHTHALMIC PROCEDURES
Embodiments disclosed herein provide a system for controlling laser transmission during an ophthalmic procedure. The system includes first and second laser sources, an optical fiber, and a signal detector. The first and second laser sources are configured to respectively generate first and second laser beams. The optical fiber is configured to receive the first and second laser beams from the first and second laser sources, transmit the first and second laser beams from a distal end of the optical fiber, receive a reflected portion of the second laser beam, and direct the reflected portion to the signal detector. The signal detector is configured to receive the reflected portion from the optical fiber, and generate a signal detector output based on the reflected portion. The signal detector output is indicative of a presence or an absence of a bubble or vapor at the distal end of the optical fiber.
Materials and methods of manufacturing intraocular lenses, including polymeric materials for the intraocular lenses, fluids for intraocular lenses, and adhesives for intraocular lenses. The intraocular lenses can include an optic portion and a peripheral region in fluid communication.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
C09J 4/00 - Adhésifs à base de composés non macromoléculaires organiques ayant au moins une liaison non saturée carbone-carbone polymérisable
C09J 4/06 - Adhésifs à base de composés non macromoléculaires organiques ayant au moins une liaison non saturée carbone-carbone polymérisable en combinaison avec un composé macromoléculaire autre qu'un polymère non saturé des groupes
G02C 7/08 - Verres auxiliairesDispositions pour faire varier la distance focale
An apparatus that can be used to fold an intraocular lens or other implant before inserting it into an eye in various locations using variable surgical techniques. Some embodiments may comprise or consist essentially of a haptic folding mechanism configured to fold one or more haptics onto the top of an optic prior to the optic being folded into a nozzle. In some embodiments, a leading haptic lifter or lifting mechanism can be configured to raise and constrain a leading haptic during implant delivery. This leading haptic folding mechanism can actively lift the leading haptic onto the top of the optic.
In certain embodiments, a robotic system for an ophthalmic injection facility includes one or more patient transportation robots and an ophthalmic injection robot located in a treatment hub of the ophthalmic injection facility. Each patient transportation robot includes a drive system, one or more sensors, a patient interface (PI) system, a chair, and a control system configured to navigate to the treatment hub based on the sensor data. The ophthalmic injection robot includes a support frame, a robotic arm, and a control system. The robotic arm includes one or more cameras and a docking assembly including a needle. The control system is configured to position the docking assembly to couple the docking assembly to a PI device attached to an eye of the patient, inject a drug through the needle into the eye of the patient, and position the docking assembly to decouple the docking assembly from the PI device.
A61B 34/32 - Robots chirurgicaux opérant de façon autonome
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61G 15/02 - Chaises avec des moyens pour régler la position du patientLeurs commandes
G05D 1/00 - Commande de la position, du cap, de l'altitude ou de l'attitude des véhicules terrestres, aquatiques, aériens ou spatiaux, p. ex. utilisant des pilotes automatiques
In certain embodiments, a method of controlling a light engine of an illumination system includes receiving, from a user input device, a desired color and a desired total flux output of a light engine; obtaining color signature data for each light emitting diode (LED) of the light engine; obtaining power flux data for each LED of the light engine; determining a power command for each LED based on the color signature data for each LED, the power flux data for each LED, the desired color, and the desired total flux output; and sending each power command to the LED to generate the desired color and the desired total flux output from the light engine. In certain embodiments, the light engine may include a red LED, a green LED, and a blue LED.
Embodiments disclosed herein provide an ophthalmic illumination device. The ophthalmic illumination device includes a first optical fiber having a proximal end and a distal end, and a second optical fiber having a proximal end and a distal end. The proximal end of the first optical fiber is coupled to a light source that provides an illumination light, and the distal end of the first optical fiber is disposed within a first ferrule. The proximal end of the second optical fiber is disposed within a second ferrule, and the distal end of the second optical fiber is configured to transmit the illumination light received from the first optical fiber into an interior portion of a patient’s eye. The first ferrule is disposed against the second ferrule to couple the distal end of the first optical fiber with the proximal end of the second optical fiber.
F21V 8/00 - Utilisation de guides de lumière, p. ex. dispositifs à fibres optiques, dans les dispositifs ou systèmes d'éclairage
G02B 6/255 - Épissage des guides de lumière, p. ex. par fusion ou par liaison
G02B 6/38 - Moyens de couplage mécaniques ayant des moyens d'assemblage fibre à fibre
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
69.
OPHTHALMIC MICROSCOPE WITH INTEGRATED VESSEL DETECTION
A system includes an ophthalmic microscope configured to capture video of an ophthalmic treatment. A computer system is coupled to the ophthalmic microscope and is configured to: receive a first image from the ophthalmic microscope for a first wavelength band having a first width of less than 20 nanometers; receive a second image from the ophthalmic microscope for a second wavelength band having a second width of less than 20 nanometers; generate a vessel map of a retina of the eye of the patient according to the first image and the second image, the vessel map including representations of blood vessels of the retina; and display the vessel map on a display device. The computer system may further receive a reference image for an isosbestic wavelength band of oxygenated and de-oxygenated hemoglobin and generate the vessel map according to the reference image.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
Intra-ocular lens (IOL) data describing an IOL model is processed using a machine learning model to obtain a selected calculator of a plurality of calculators that may be used to estimate the post-operative refractive error of the IOL model. The IOL data may be processed with patient data, such as eye measurements and patient history. Eye measurements may include anterior chamber depth (ACD) and white-to-white (WTW) distance. Patient history may include whether an eye has undergone past refractive error correction surgery. The selected calculator may be used to calculate a post-operative refractive error to guide selection of an IOL.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/103 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p. ex. réfractomètres, skiascopes
A computer-implemented method of resource-efficient consent management. Embodiments include receiving, at a device, an indication that consent has been given with respect to one or more items. Embodiments include determining, at the device, a binary bit pattern representative of the indication based on a configured association between the one or more items and one or more values in the binary bit pattern. Embodiments include storing, at the device, a memorialization of the indication via a bit vector having the binary bit pattern.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
In certain embodiments, a robotic system for a surgical facility includes a dispenser, a delivery robot, and a setup robot located in an operating room. The delivery robot includes a drive system, sensors, a robotic arm including a camera and a gripper, and a control system that is configured to navigate to the dispenser based on sensor data, retrieve a bin containing a surgical package from the dispenser, navigate to a storage table in the operating room based on the sensor data, and deliver the packages to the storage table. The setup robot includes a robotic arm including first and second end effectors, and a control system that is configured to open the surgical package located on the storage table, remove items from the surgical package, and deposit the items on a sterile tray in the operating room.
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61B 34/00 - Chirurgie assistée par ordinateurManipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
In general, embodiments of the present disclosure relate to pigment containing contact lenses, such as colored contact lenses. In particular, embodiments of the present disclosure relate to a hybrid hard-soft silicone hydrogel contact lens. In at least some embodiments, a method for forming a contact lens is provided. The method includes printing a pigmented layer on a lens mold including an optic zone and curing the pigmented layer with ultraviolet (UV) light. The pigmented layer is printed outside an outer boundary of the optic zone of the lens mold. The method further includes forming an insert lens layer, the insert lens layer disposed on the cured pigmented layer, curing the insert lens layer to form an insert lens having a modulus of greater than about 2 MPa, suspending the insert lens in a lens-forming material and curing the lens-forming material to form a lens body.
B29D 11/00 - Fabrication d'éléments optiques, p. ex. lentilles ou prismes
B29K 83/00 - Utilisation de polymères contenant dans la chaîne principale uniquement du silicium avec ou sans soufre, azote, oxygène ou carbone comme matière de moulage
B29K 105/00 - Présentation, forme ou état de la matière moulée
A computer-implemented method of automated dosing optimization for photo-bio- modulation (PBM) treatment. Embodiments include a light source of a multi-spectral imaging device configured to generate outgoing light across a range of wavelengths, one or more filters of the multi-spectral imaging device configured to generate incoming light to allow only a subset of wavelengths from the range of wavelengths to pass through, and one or more sensors of the multi-spectral imaging device configured to detect the filtered incoming light. Embodiments include one or more processors configured to execute instructions that cause the system to generate, based on the detecting of the filtered incoming light, a set of multi-spectral images of an eye of a patient, and generate, based on the set of multi-spectral images and one or more attributes of the patient, a PBM dosing regimen for the patient.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
75.
OPTHALMIC STRUCTURE MODELING BASED EYE REGISTRATION
The present disclosure relates to operations that include generating, based on a first image of a first depiction of an eye in a first dilation state and a second image of a second depiction of the eye in a second dilation state, a third depiction of the eye in the second dilation state. Further, the operations may include determining an alignment registration between the first depiction of the eye and the second depiction of the eye based on a comparison between the second depiction and the third depiction.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
A61B 3/11 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la distance interpupillaire ou le diamètre de la pupille
G06V 40/18 - Caractéristiques de l’œil, p. ex. de l’iris
76.
METHOD FOR DETERMINING THE INVERSION STATE OF A SOFT CONTACT LENS
A method for determining the inversion state of a soft contact lens which is arranged in an interior space of an inspection cuvette comprises the steps of: through the viewing glass obtaining a dark-field image of the soft contact lens arranged in the interior space along the optical axis; identifying a lens edge of the soft contact lens in the dark-field image; determining one characteristic values representative of the brightness of a portion of the lens edge in the dark-field image; comparing one of the characteristic values with a corresponding predetermined threshold value; and determining that the soft contact lens is inverted in case the characteristic values is equal to or above the corresponding predetermined threshold value.
In certain embodiments, a robotic system for performing cataract surgery includes a base, a robotic mechanism, and a control system. The robotic mechanism includes a patient interface configured to be coupled to the head of a patient, an end effector configured to receive an exchangeable tool, and sensors that include a polarization camera, a stereo camera, and an optical coherence tomography (OCT) sensor. The control system includes a processor configured to fuse the polarized image data, the stereo image data, and the depth image data to generate fused sensor data of a region of the eye including the cornea and the lens, determine the location of a phacoemulsification tool coupled to the end effector based on the fused sensor data, and control the end effector and the phacoemulsification tool, based on the phacoemulsification tool location, to remove the lens through an incision in the cornea.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p. ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A drug delivery device includes a conveyor and a docking assembly movable by the conveyor to a plurality of patient stations. The docking assembly includes one or more imaging devices configured to have an eye of the patient in a field of view thereof. The docking assembly includes an injection assembly and a staging assembly including one or more actuators and configured to position the injection assembly relative to the eye of the patient. A controller is configured to receive one or more images from the one or more imaging devices; detect anatomy of the eye of the patient in the one or more images; and activate the one or more actuators to drive a needle mounted to the injection assembly into a placement location on the eye of the patient according to the location of the anatomy. A loader loads injection assemblies into the docking assembly.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A wide-angle viewing system (WAVS) for an ophthalmic microscope is provided. The WAVS includes a frame, a reduction lens module attached to the frame, and an image inverter-reverter module movably coupled to the frame. The reduction lens module includes an ophthalmic microscope mount, and a movable reduction lens assembly with an optical axis, a disengaged position, and an engaged position. The image inverter-reverter module includes an optical prism and a loupe lens assembly. The image inverter-reverter module has an optical axis, a stowed position, and a deployed position. When the movable reduction lens assembly is disposed in the engaged position, the optical axis of the movable reduction lens assembly is aligned with the optical axis of the ophthalmic microscope. When the image inverter-reverter module is disposed in the deployed position, the optical axis of the image inverter-reverter module is aligned with the optical axis of the ophthalmic microscope.
One or more images of an eye of a patient having an implanted IOL are received. The one or more images are captured using one or more imaging devices having one or more imaging modalities. A computing device determines misalignment of the IOL according to the one or more images and processes the misalignment using a predictive model to obtain an improvement probability. The computing device outputs an intervention recommendation according to the improvement probability. The intervention recommendation may be the result of cost/benefit analysis of the improvement probability.
A61B 3/18 - Agencement de plusieurs appareils pour tester ou examiner les yeux
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/103 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p. ex. réfractomètres, skiascopes
A61B 3/107 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
An ophthalmic surgical system includes a biomechanical imaging device configured to perform measurements of an eye of a patient. The system further includes a controller configured to: receive Brillouin light scattering (BLS) data from the BLS imaging device; calculate material properties according to the BLS data; select a tissue type according to the material properties; and generating an output corresponding to the tissue type. The biomechanical imaging device may include a confocal Brillouin microscope or a BLS spectrometer and a light source coupled to a fiber optic probe. Tissue types may include a retinal membrane, type of retinal membrane, or membrane-free area of the retina.
A retina visualization system includes a laser device operable for outputting a primary laser beam, the laser device including a red, green, blue (RGB) diode array and an infrared (IR) diode, along with a stereo, confocal, biaxial microelectromechanical system (MEMS) scanning system. The scanning system receives the primary laser beam and outputs a scanning laser toward an eye along a visualization path. A Shack Hartmann wavefront sensor proximate the eye senses wavefront distortion in light reflected from the eye. A wavefront control device corrects the wavefront distortion in response to a control signal. A stereo pair of avalanche photodiode (APD) detectors detects light and generates an electronic signal in response thereto. An electronic control unit (ECU) transmits the control signal the wavefront control device to cause the wavefront control device to correct the wavefront distortion into a corrected wavefront, with corrected images displayed via a stereo display device.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
In certain embodiments, a robotic system for performing cataract surgery includes a base, a robotic mechanism, and a control system. The robotic mechanism includes a patient interface configured to be coupled to the head of a patient, an end effector configured to receive an exchangeable tool, and sensors that include a polarization camera, a stereo camera, and an optical coherence tomography (OCT) sensor. The control system includes a processor configured to fuse the polarized image data, the stereo image data, and the depth image data to generate fused sensor data of a region of the eye including the cornea and the lens, determine the location of a phacoemulsification tool coupled to the end effector based on the fused sensor data, and control the end effector and the phacoemulsification tool, based on the phacoemulsification tool location, to remove the lens through an incision in the cornea.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
G06T 5/50 - Amélioration ou restauration d'image utilisant plusieurs images, p. ex. moyenne ou soustraction
In certain embodiments, a robotic system for an ophthalmic injection facility includes one or more patient transportation robots and an ophthalmic injection robot located in a treatment hub of the ophthalmic injection facility. Each patient transportation robot includes a drive system, one or more sensors, a patient interface (PI) system, a chair, and a control system configured to navigate to the treatment hub based on the sensor data. The ophthalmic injection robot includes a support frame, a robotic arm, and a control system. The robotic arm includes one or more cameras and a docking assembly including a needle. The control system is configured to position the docking assembly to couple the docking assembly to a PI device attached to an eye of the patient, inject a drug through the needle into the eye of the patient, and position the docking assembly to decouple the docking assembly from the PI device.
A61G 5/04 - Fauteuils ou moyens de transport personnels spécialement adaptés pour des personnes handicapées, p. ex. fauteuils roulants à moteur
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeuxDispositifs pour mettre en place des verres de contactDispositifs pour corriger le strabismeAppareils pour guider les aveuglesDispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
Embodiments of the present disclosure generally relate to methods and processes for forming an ophthalmic product, such as contact lenses. More specifically, embodiments described herein relate to the production of contact lenses having a water-soluble phospholipid polymer disposed thereon, which may be released therefrom as an ophthalmic comfort agent during use of the contact lens. In some embodiments, a contact lens includes a bulk layer having a crosslinked polymeric material, and a poly(vinyl alcohol) (PVA) layer disposed on the bulk layer. The contact lens further includes a water-soluble phospholipid polymer disposed on the PVA layer. The water-soluble phospholipid polymer includes a plurality of phosphorylcholine units and a plurality of arylborono units.
G02B 1/04 - Éléments optiques caractérisés par la substance dont ils sont faitsRevêtements optiques pour éléments optiques faits de substances organiques, p. ex. plastiques
B65B 17/00 - Autres machines, appareils ou procédés pour emballer des objets ou des matériaux
An ophthalmic surgical instrument for peeling a retinal membrane includes a handle and an actuator mounted on the handle. An outer tube is mounted to the handle and an inner rod extends within the outer tube. A grasping structure is secured to a distal end of the inner rod having first and second polymer arms secured to the inner rod. Each of the first polymer arm and the second polymer arms has a distal end that is angled to conform to the retinal membrane. The actuator is configured to control relative position of the inner rod and the outer tube in order to extend the grasping structure out of the outer tube and withdraw the grasping structure within the outer tube.
A wide-angle viewing system (WAVS) for an ophthalmic microscope is provided. The WAVS includes a frame, a reduction lens module attached to the frame, and an image inverter-reverter module movably coupled to the frame. The reduction lens module includes an ophthalmic microscope mount, and a movable reduction lens assembly with an optical axis, a disengaged position, and an engaged position. The image inverter-reverter module includes an optical prism and a loupe lens assembly. The image inverter-reverter module has an optical axis, a stowed position, and a deployed position. When the movable reduction lens assembly is disposed in the engaged position, the optical axis of the movable reduction lens assembly is aligned with the optical axis of the ophthalmic microscope. When the image inverter-reverter module is disposed in the deployed position, the optical axis of the image inverter-reverter module is aligned with the optical axis of the ophthalmic microscope.
In certain embodiments, a method of controlling a light engine of an illumination system includes receiving, from a user input device, a desired color and a desired total flux output of a light engine; obtaining color signature data for each light emitting diode (LED) of the light engine; obtaining power flux data for each LED of the light engine; determining a power command for each LED based on the color signature data for each LED, the power flux data for each LED, the desired color, and the desired total flux output; and sending each power command to the LED to generate the desired color and the desired total flux output from the light engine. In certain embodiments, the light engine may include a red LED, a green LED, and a blue LED.
An ophthalmic surgical system includes a biomechanical imaging device configured to perform measurements of an eye of a patient. The system further includes a controller configured to: receive Brillouin light scattering (BLS) data from the BLS imaging device; calculate material properties according to the BLS data; select a tissue type according to the material properties; and generating an output corresponding to the tissue type. The biomechanical imaging device may include a confocal Brillouin microscope or a BLS spectrometer and a light source coupled to a fiber optic probe. Tissue types may include a retinal membrane, type of retinal membrane, or membrane-free area of the retina.
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
An ophthalmic surgical system includes an item of ophthalmic surgical equipment and one or more computing devices. The one or more computing devices are configured to receive a three-dimensional image of an eye of a patient; process the three-dimensional image using a machine learning model to obtain a density map of a crystalline lens of the eye of the patient; and control the item of surgical equipment according to the density map. The item of surgical equipment may be a treatment laser or phaco-vit tool. Aspiration pressure of the phaco-vit tool may be controlled based on a position of a distal end of the phaco-vit tool and a corresponding density in the density map.
A computer-implemented method of resource-efficient consent management. Embodiments include receiving, at a device, an indication that consent has been given with respect to one or more items. Embodiments include determining, at the device, a binary bit pattern representative of the indication based on a configured association between the one or more items and one or more values in the binary bit pattern. Embodiments include storing, at the device, a memorialization of the indication via a bit vector having the binary bit pattern.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p. ex. pour la gestion du personnel hospitalier ou de salles d’opération
An ophthalmic surgical system includes an item of ophthalmic surgical equipment and one or more computing devices. The one or more computing devices are configured to receive a three-dimensional image of an eye of a patient; process the three-dimensional image using a machine learning model to obtain a density map of a crystalline lens of the eye of the patient; and control the item of surgical equipment according to the density map. The item of surgical equipment may be a treatment laser or phaco-vit tool. Aspiration pressure of the phaco-vit tool may be controlled based on a position of a distal end of the phaco-vit tool and a corresponding density in the density map.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p. ex. ophtalmoscopes
A61B 34/20 - Systèmes de navigation chirurgicaleDispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p. ex. pour la stéréotaxie sans cadre
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
In certain embodiments, a system configured to illuminate an eye includes a pattern illuminator and an illuminator computer. The pattern illuminator provides an illumination pattern directed towards the anterior surface of the eye. The anterior surface of the eye reflects the illumination pattern as a reflected illumination pattern. The illuminator computer receives, via a wireless communication link, a set of instructions configured to coordinate the illumination pattern with a device of one or more devices of an ophthalmic system. The illuminator computer instructs the pattern illuminator to provide the illumination pattern according to the set of instructions to coordinate the illumination pattern with the device of the ophthalmic system.
A61B 3/00 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
96.
MACHINE LEARNING BASED OPTIMIZATION OF PHOTO-BIO-MODULATION DOSING
A computer-implemented method of automated dosing optimization for photo-bio- modulation (PBM) treatment. Embodiments include a light source of a multi-spectral imaging device configured to generate outgoing light across a range of wavelengths, one or more filters of the multi-spectral imaging device configured to generate incoming light to allow only a subset of wavelengths from the range of wavelengths to pass through, and one or more sensors of the multi- spectral imaging device configured to detect the filtered incoming light. Embodiments include one or more processors configured to execute instructions that cause the system to generate, based on the detecting of the filtered incoming light, a set of multi-spectral images of an eye of a patient, and generate, based on the set of multi-spectral images and one or more attributes of the patient, a PBM dosing regimen for the patient.
The present disclosure relates to operations that include generating, based on a first image of a first depiction of an eye in a first dilation state and a second image of a second depiction of the eye in a second dilation state, a third depiction of the eye in the second dilation state. Further, the operations may include determining an alignment registration between the first depiction of the eye and the second depiction of the eye based on a comparison between the second depiction and the third depiction.
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c.-à-d. recalage des images utilisant des procédés basés sur les caractéristiques
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A method for determining the inversion state of a soft contact lens which is arranged in an interior space of an inspection cuvette comprises the steps of: through the viewing glass obtaining a dark-field image of the soft contact lens arranged in the interior space along the optical axis; identifying a lens edge of the soft contact lens in the dark-field image; determining one characteristic values representative of the brightness of a portion of the lens edge in the dark-field image; comparing one of the characteristic values with a corresponding predetermined threshold value; and determining that the soft contact lens is inverted in case the characteristic values is equal to or above the corresponding predetermined threshold value.
In certain embodiments, an ophthalmic system and computer-implemented method for automatically initializing an image guided surgery are described. The initialization includes monitoring a scene using multiple images captured by a first imaging device. An eye of a user is detected within a first image of the multiple images. In response to detecting the eye of the user, a registration procedure is initiated with the first image and a reference image of the eye of the user to generate a set of transformation information. A set of overlay content is generated based on the set of transformation information. The set of overlay content includes a transformed first image or a transformed reference image. Overlay content is presented onto the scene via a second imaging device.
Provided herein are topical ophthalmic pharmaceutical compositions of (1R,2S,5R)-2-isopropyl-N-(4- methoxyphenyl)-5-methylcyclohexane-1-carboxamide (WS-12, acoltremon) in LDPE containers, their methods of manufacture, and uses thereof in ocular therapeutics.