Abstract

The present invention provides a compound comprising a polypeptide conjugated to an immunogenic carrier, the polypeptide comprising the sequence EGPWLEEEEEAYG (SEQ ID NO: 1) and having fewer than 17 amino acid residues, for use in medicine. Further, the invention provides a compound comprising a polypeptide conjugated to an immunogenic carrier, the polypeptide comprising the sequence EGPWLEEEEEAYG (SEQ ID NO: 1) and having fewer than 17 amino acid residues, wherein the immunogenic carrier is diphtheria toxoid, tetanus toxoid, keyhole limpet haemocyanin, Purified protein derivative (PPD), Albumin, and/or viral proteins. The polypeptide may be conjugated to the immunogenic carrier via a cysteine residue. Pharmaceutical compositions and kits of parts are also provided. In particular, the use of the compounds in medicine and in the treatment of cancer is provided.

IPC Classes  ?

• A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• C07K 14/595 - GastrinsCholecystokinins [CCK]
• A61P 35/00 - Antineoplastic agents