Abrégé

The present invention provides a compound comprising a polypeptide conjugated to an immunogenic carrier, the polypeptide comprising the sequence EGPWLEEEEEAYG (SEQ ID NO: 1) and having fewer than 17 amino acid residues, for use in medicine. Further, the invention provides a compound comprising a polypeptide conjugated to an immunogenic carrier, the polypeptide comprising the sequence EGPWLEEEEEAYG (SEQ ID NO: 1) and having fewer than 17 amino acid residues, wherein the immunogenic carrier is diphtheria toxoid, tetanus toxoid, keyhole limpet haemocyanin, Purified protein derivative (PPD), Albumin, and/or viral proteins. The polypeptide may be conjugated to the immunogenic carrier via a cysteine residue. Pharmaceutical compositions and kits of parts are also provided. In particular, the use of the compounds in medicine and in the treatment of cancer is provided.

Classes IPC  ?

• A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
• C07K 7/08 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 12 à 20 amino-acides
• C07K 14/595 - GastrinesCholécystokinines [CCK]
• A61P 35/00 - Agents anticancéreux