Abstract

The present invention relates to a catalytic hydrogenation reaction and a use of a manganese-based catalyst, and in particular to using a manganese-based multidentate ligand compound to carry out a catalytic hydrogenation reaction on urea or a derivative thereof or a carbamate compound. Moreover, the present invention first proposes new use of the manganese-based multidentate ligand compound in the reaction.

IPC Classes  ?

• C07C 231/10 - Preparation of carboxylic acid amides from compounds not provided for in groups
• C07C 233/15 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
• C07C 233/03 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to hydrogen atoms
• C07C 273/18 - Preparation of urea or its derivatives, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
• C07C 275/30 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
• C07C 275/28 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
• C07C 275/26 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
• C07C 275/06 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
• B01J 31/24 - Phosphines
• B01J 31/22 - Organic complexes
• B01J 31/20 - Carbonyls

Abstract

The present invention relates to a catalyst system for a carbonylation reaction and a method for a carbonylation reaction. The catalyst system comprises: (a) a group VIII metal or a compound of the group VIII metal; (b) a bidentate phosphine ligand; and (c) an acidic additive. The component (b) is represented by the following formula (I): R1>P-A-Ar-B-P

IPC Classes  ?

• B01J 31/24 - Phosphines
• C07F 9/6568 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms
• C07F 9/6571 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
• C07F 9/6584 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
• C07F 9/50 - Organo-phosphines
• C07C 67/38 - Preparation of carboxylic acid esters by reaction with carbon monoxide or formates by addition to an unsaturated carbon-to-carbon bond
• C07C 69/24 - Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
• C07C 69/612 - Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
• C07C 69/75 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of acids with a six-membered ring

Abstract

A mesoporous nickel powder and a preparation method therefor, and a nickel-phosphorus catalyst system. The mesoporous nickel powder comprises powder-like particles of metallic nickel, the average particle size of the particles being 1-100 μm, the average pore diameter being 10-60 nm, the pore volume being 0.02-0.09 cm3/g, and the BET specific surface area being 5.0-40.0 m2/g. The preparation method for the mesoporous nickel powder comprises: a hydrothermal synthesis step; a templating agent removal step; and a reduction step; the templating agent is a triblock copolymer comprising an A-B-A structure, or a disulfide bond diblock copolymer comprising an A-S-S-B structure. The nickel-phosphorus catalyst system comprises a complex formed by the mesoporous nickel powder and a phosphorus ligand.

IPC Classes  ?

• B22F 1/05 - Metallic powder characterised by the size or surface area of the particles
• B22F 1/06 - Metallic powder characterised by the shape of the particles
• B22F 9/22 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from solid metal compounds using gaseous reductors
• B01J 31/22 - Organic complexes
• C07C 253/10 - Preparation of carboxylic acid nitriles by addition of hydrogen cyanide or salts thereof to unsaturated compounds to compounds containing carbon-to-carbon double bonds
• C07C 255/04 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton containing two cyano groups bound to the carbon skeleton

Abstract

Disclosed in the present invention is a method for preparing epsilon-caprolactone by using an in-situ peroxide. The method efficiently utilizes an in-situ peroxide obtained in a process of oxidizing alcohol by oxygen to oxidize cyclohexanone into epsilon-caprolactone, i.e., under the catalysis of a catalyst, an alcohol is oxidized into a corresponding ketone while substances such as hydroxyl peroxide or hydrogen peroxide generated in the process are fully utilized, so that a Baeyer-Villiger oxidation reaction from cyclohexanone to epsilon-caprolactone is realized. Compared with a previous epsilon-caprolactone synthesis method, the present method has the advantages that the product yield is remarkably increased, the use efficiency of alcohol is further improved, raw materials and reagents are cheap and easy to obtain, operation is easy, reaction conditions are mild, and the method is clean and environmentally friendly.

IPC Classes  ?

• C07D 313/04 - Seven-membered rings not condensed with other rings

Abstract

The present invention relates to a method for preparing an oxazole compound. An additive represented by a formula (I) or (II) or (III) is added into an organic solvent and organic alkali (especially triethylamine), an organic solution of phosgene or diphosgene or triphosgene is dropwise added to perform a cyclization reaction with a compound (IV), and thus a product (V) at a high yield can be obtained and the generation of byproducts can be greatly inhibited. The reaction conditions in the present invention are mild, and compared with a method without addition of additives, the technical solution in the present invention can improve the yield of the product (V) to 95% or more and reduce the byproducts by 10% or more.

IPC Classes  ?

• C07D 263/42 - One oxygen atom attached in position 5

Abstract

The present invention relates to a catalyst for a phosgenation reaction and a phosgenation reaction method. The catalyst for a phosgenation reaction of the present invention is a phosphinyl ionic liquid as represented by general formula (I). In addition, the phosgenation reaction method provided by the present invention is a phosgenation reaction method using phosgene as a chlorination agent, and in the phosgenation reaction method, the catalyst for a phosgenation reaction as provided by the present invention is used. Compared with the use of the catalyst of triphenylphosphine oxide, etc., in a phosgenation reaction, the catalyst provided by the present invention can result in the charge rate of phosgene in a phosgenation reaction being reduced and the reaction time being shortened, thereby indicating a higher reaction efficiency and a higher atomic utilization of phosgene.

IPC Classes  ?

• B01J 31/24 - Phosphines
• C07C 17/00 - Preparation of halogenated hydrocarbons
• C07C 17/013 - Preparation of halogenated hydrocarbons by addition of halogens
• C07C 17/18 - Preparation of halogenated hydrocarbons by replacement by halogens of oxygen atoms of carbonyl groups
• C07C 21/04 - Chloro-alkenes
• C07C 22/00 - Cyclic compounds containing halogen atoms bound to an acyclic carbon atom
• C07C 22/04 - Cyclic compounds containing halogen atoms bound to an acyclic carbon atom having unsaturation in the rings containing six-membered aromatic rings
• C07C 51/60 - Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides into halides with the same carboxylic acid part
• C07H 1/00 - Processes for the preparation of sugar derivatives
• C07H 13/04 - Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
• C07B 39/00 - Halogenation
• C07C 53/38 - Acyl halides

Abstract

The present application relates to a method for preparing 3-hydroxypropionitrile. The method for preparing 3-hydroxypropionitrile comprises: reacting acrylonitrile with a supercritical water, and separating the obtained reaction solution to obtain the 3-hydroxypropionitrile.

IPC Classes  ?

• C07C 253/30 - Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
• C07C 255/12 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton

Abstract

Disclosed is a method for preparing a lactone compound, the method comprising performing an oxidation reaction on a cyclic ketone using molecular oxygen in the presence of an organic nitrogen-oxygen radical precursor, a free radical initiator, an alcohol and a Sn-based catalyst, or performing an oxidation reaction on a cyclic alcohol using molecular oxygen in the presence of an organic nitrogen-oxygen radical precursor, a Sn-based catalyst and a free radical initiator.

IPC Classes  ?

• C07D 313/04 - Seven-membered rings not condensed with other rings
• C07D 313/10 - Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings

Abstract

The present disclosure relates to a method for preparing isophorone diamine by means of a hydrogenation reduction of isophorone nitrile imine. The hydrogenation reduction is continuously carried out in a multi-stage bubble column reactor loaded with a supported alkaline cobalt-based catalyst, wherein isophorone nitrile imine is successively in countercurrent contact with hydrogen in each stage of the reactor to carry out a hydrogenation reduction reaction, so as to obtain the isophorone diamine. The preparation method solves the problem of back-mixing, and further improves the conversion rate and the cis/trans ratio of the product.

IPC Classes  ?

• C07C 209/52 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
• B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
• B01J 35/04 - Foraminous structures, sieves, grids, honeycombs
• C07C 209/48 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles

Abstract

66.

IPC Classes  ?

• C07D 263/42 - One oxygen atom attached in position 5
• C07D 213/66 - One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulfur, or nitrogen atom, e.g. pyridoxal

Abstract

3 are identical groups, partially identical groups, or different groups from each other. According to the method, the reaction conversion rate and selectivity are greatly improved; moreover, it is easy to realize industrial application.

IPC Classes  ?

• C07H 1/06 - SeparationPurification
• C07H 5/02 - Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen

Abstract

Provided by the present invention is a device used for evaporation and crystallization. The device comprises an evaporation container and a crystallization container. The device used for evaporation and crystallization further comprises a first circulation unit and a second circulation unit. The first circulation unit comprises a first branch pipe, a first circulation pump, and a first circulation inlet pipe that are successively connected. The second circulation unit comprises a second branch pipe, a second circulation pump, a heater, and a second circulation inlet pipe that are successively connected. The first circulation inlet pipe and the second circulation inlet pipe are connected to the evaporation container. By means of providing an additional first circulation loop, a portion of fine crystals are reintroduced into the crystallization container as a crystal nucleus, and a product that has more uniform particles and a controllable particle size is finally obtained.

IPC Classes  ?

• B01D 9/02 - Crystallisation from solutions

Abstract

A method for synthesizing sucrose-6-ester. The method comprises: (a) in the presence of a polar aprotic solvent, contacting an organic phosphine compound represented by formula I with sucrose and an organic tin compound; (b) removing water to obtain a reaction liquid containing a tin-sucrose adduct; and (c) contacting the reaction liquid containing the tin-sucrose adduct with an acid anhydride compound to prepare sucrose-6-ester. (Formula I). R1, R2, and R3in formula I each are linear or branched alkyl containing 1-20 carbon atoms, cycloalkyl containing 3-10 carbon atoms, or aryl containing 6-10 carbon atoms; moreover, the R1, R2, and R3 are identical groups, partially identical groups, or different groups. According to the method, the reaction conversion efficiency and selectivity are greatly improved, and the molar yield of sucrose-6-ester can reach more than 92% and even can reach 95.3%; moreover, it is easy to implement industrial application.

IPC Classes  ?

• C07H 13/04 - Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
• C07H 13/06 - Fatty acids

Abstract

The present invention relates to a method for preparing isophorone diamine by means of a hydrogenation reduction of isophorone nitrile imine. The hydrogenation reduction is continuously carried out in a multi-stage bubble column reactor loaded with a supported alkaline cobalt catalyst, wherein isophorone nitrile imine is successively in countercurrent contact with hydrogen in each stage of the reactor, so as to obtain the isophorone diamine. The preparation method solves the problem of back-mixing, and further improves the conversion rate and the cis:trans product ratio.

IPC Classes  ?

• C07C 209/52 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
• C07C 209/48 - Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
• C07C 211/36 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
• B01J 8/02 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with stationary particles, e.g. in fixed beds