The present invention relates to a composition of paeoniflorin and isoliquiritigenin and the use thereof. The composition of the present invention involves rich raw materials, has the effects of resisting inflammation, resisting oxidation, inhibiting collagen deposition and the like, can be effectively used for treating diffuse pulmonary interstitial fibrosis, and has relatively high economic and social benefits.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61P 11/00 - Drugs for disorders of the respiratory system
2.
USE OF COMPOUND WITH ANTI-KIDNEY INJURY ACTIVITY IN PREPARATION OF ANTI-KIDNEY INJURY DRUG
Provided is the use of a compound with an anti-kidney injury activity in the preparation of an anti-kidney injury drug. 7-O-ethyl-Morroniside from Corni fructus has an anti-kidney injury effect, and such effect may be related to 7-O-ethyl-Morroniside from Corni fructus having the function of inhibiting kidney injury induced by advanced glycation end products (AGEs). Therefore, 7-O-ethyl-Morroniside from Corni fructus has the prospect of being developed into an anti-kidney injury drug.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A traditional Chinese medicine fermented preparation for preventing and treating gout is prepared by combining a traditional Chinese medicine formula with probiotics. The traditional Chinese medicine formula includes a certain proportion of Aconitum carmichaeli, Cinnamomum cassia, Ephedra sinica, Atractylodes lancea, Saposhnikovia divaricate, Smilax glabra, Paeonia lactiflora, Anemarrhena asphodeloides, Coix lacryma-jobi, gypsum, and Glycyrrhiza uralensis. The probiotics includes Lactobacillus plantarum, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus rhamnosus and yeast. Drug bioavailability is improved by fermentation, maximizing therapeutic effects. A combination application of different probiotics plays a very important role in regulating and optimizing intestinal microbiota of a body, making clinical treatment of the gout more effective.
Lactobacillus acidophilus are inoculated for fermenting, and a liquid fermented mixture is mixed to obtain fermentation preparation. The traditional Chinese medicine compound has a definite therapeutic effect, reasonable compatibility, a wide range of materials, and a low price, which makes it easy to promote and apply.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Disclosed in the present invention is a medical use of astragaloside I. The present invention found that astragaloside I has anti-kidney-injury effects, and the effects of astragaloside I may be related to the function thereof suppressing kidney injuries induced by advanced glycation end products (AGEs). Therefore, astragaloside I has the prospect of being developed into anti-kidney-injury drugs.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A pharmaceutical formulation for preventing and treating Alzheimer's disease. Ilexgenin O or a pharmaceutically acceptable salt thereof is used as an active pharmaceutical ingredient and prepared to be a pharmaceutically acceptable formulation dosage form. Ilexgenin O and the pharmaceutically acceptable salt thereof are applied in the preparation of a medication for preventing and treating Alzheimer's disease.
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
7.
USE OF TARAXASTEROL FOR PREPARING DRUG FOR PREVENTING AND TREATING ALZHEIMER'S DISEASE
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
patents
