The present invention relates to a composition of paeoniflorin and isoliquiritigenin and the use thereof. The composition of the present invention involves rich raw materials, has the effects of resisting inflammation, resisting oxidation, inhibiting collagen deposition and the like, can be effectively used for treating diffuse pulmonary interstitial fibrosis, and has relatively high economic and social benefits.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 31/122 - Cétones ayant l'atome d'oxygène lié directement à un cycle, p. ex. quinones, vitamine K1, anthraline
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
2.
USE OF COMPOUND WITH ANTI-KIDNEY INJURY ACTIVITY IN PREPARATION OF ANTI-KIDNEY INJURY DRUG
Provided is the use of a compound with an anti-kidney injury activity in the preparation of an anti-kidney injury drug. 7-O-ethyl-Morroniside from Corni fructus has an anti-kidney injury effect, and such effect may be related to 7-O-ethyl-Morroniside from Corni fructus having the function of inhibiting kidney injury induced by advanced glycation end products (AGEs). Therefore, 7-O-ethyl-Morroniside from Corni fructus has the prospect of being developed into an anti-kidney injury drug.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A traditional Chinese medicine fermented preparation for preventing and treating gout is prepared by combining a traditional Chinese medicine formula with probiotics. The traditional Chinese medicine formula includes a certain proportion of Aconitum carmichaeli, Cinnamomum cassia, Ephedra sinica, Atractylodes lancea, Saposhnikovia divaricate, Smilax glabra, Paeonia lactiflora, Anemarrhena asphodeloides, Coix lacryma-jobi, gypsum, and Glycyrrhiza uralensis. The probiotics includes Lactobacillus plantarum, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus rhamnosus and yeast. Drug bioavailability is improved by fermentation, maximizing therapeutic effects. A combination application of different probiotics plays a very important role in regulating and optimizing intestinal microbiota of a body, making clinical treatment of the gout more effective.
Lactobacillus acidophilus are inoculated for fermenting, and a liquid fermented mixture is mixed to obtain fermentation preparation. The traditional Chinese medicine compound has a definite therapeutic effect, reasonable compatibility, a wide range of materials, and a low price, which makes it easy to promote and apply.
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
Disclosed in the present invention is a medical use of astragaloside I. The present invention found that astragaloside I has anti-kidney-injury effects, and the effects of astragaloside I may be related to the function thereof suppressing kidney injuries induced by advanced glycation end products (AGEs). Therefore, astragaloside I has the prospect of being developed into anti-kidney-injury drugs.
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A pharmaceutical formulation for preventing and treating Alzheimer's disease. Ilexgenin O or a pharmaceutically acceptable salt thereof is used as an active pharmaceutical ingredient and prepared to be a pharmaceutically acceptable formulation dosage form. Ilexgenin O and the pharmaceutically acceptable salt thereof are applied in the preparation of a medication for preventing and treating Alzheimer's disease.
A61K 31/704 - Composés ayant des radicaux saccharide liés à des composés non-saccharide par des liaisons glycosidiques liés à un composé carbocyclique, p. ex. phloridzine liés à un système carbocyclique condensé, p. ex. sennosides, thiocolchicosides, escine, daunorubicine, digitoxine
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
7.
USE OF TARAXASTEROL FOR PREPARING DRUG FOR PREVENTING AND TREATING ALZHEIMER'S DISEASE
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
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