An automated system for processing a sample contained in a liquid sample container includes an automated tool head configured to rotate about a first axis, and to translate along a second axis different than the first axis, a pipettor carried by the tool head, the pipettor having a pipette tip engaging member configured to releasably engage pipette tips, and a supplemental container holder configured for holding a supplemental container, the tool head configured to automatically position the pipette tip engaging member into a position in which an engaged pipette tip is inserted into a sample container held in the sample container holder, and into a position in which an engaged pipette tip is inserted into a supplemental container held in the supplemental container holder, through one or both of rotation of the tool head about the first axis and translation of the tool head along the second axis.
Automated systems and methods for evaluating specimens affixed to substrates, such as slides, an exemplary system including a slide imager configured for acquiring a plurality of micro images of a specimen affixed to an substrate, the specimen including a plurality of objects distributed within a three-dimensional volume, and for generating a whole specimen image of the specimen using the micro images, wherein objects contained in the specimen are depicted substantially in focus in the whole specimen image regardless of a z-depth of the respective objects within the specimen. The whole specimen image is stored on a storage medium for subsequent review by a cytotechnologist using a computer-controlled review station including a display and a user interface, wherein the review station user interface is configured such that the cytotechnologist can review and classify the stored whole specimen images.
G10K 11/175 - Methods or devices for protecting against, or for damping, noise or other acoustic waves in general using interference effectsMasking sound
H04K 3/00 - Jamming of communicationCounter-measures
H04R 1/06 - Arranging circuit leadsRelieving strain on circuit leads
A system comprising an analyzer for performing nucleic acid amplification assays includes a controller configured to send instructions to purify a first sample by immobilizing a first analyte, purify a second sample by immobilizing a second analyte, form a first reaction mixture by combining a dissolved second reagent with the purified second sample, wherein a second solvent for dissolving the second reagent contains second amplification oligomers for amplifying the second analyte and the second reagent contains a polymerase but does not contain amplification oligomers for amplifying the second analyte, and form a second reaction mixture by combining a dissolved first reagent with the purified first sample, wherein the first reagent contains a polymerase and first amplification oligomers for amplifying the first analyte and a first solvent for dissolving the first reagent does not contain an amplification oligomer or a polymerase for amplifying the first analyte.
This disclosure provides oligomers, compositions, and kits for detecting and quantifying Hepatitis B virus (HBV), including different genotypes and variants thereof, and related methods and uses. In some embodiments, oligomers target the P and/or S open reading frames of HBV and are configured to provide substantially equivalent quantification of different genotypes and variants of HBV.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
Disclosed are methods utilizing specific amplification of Candida sp. target nucleic acid for detecting the presence or absence of Candida sp. in a sample. Also disclosed are corresponding oligomers, including amplification oligomers, capture probes and detection probes, and combinations thereof, as well as corresponding reaction mixtures and kits.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Analyzing samples using an automated analyzer comprises retaining a first container containing a first solvent lacking an amplification oligomer at a first location of the analyzer, retaining a second container having a different structure than the first container and supporting solvent-containing vials at a second location of the analyzer, the solvent in each vial including an amplification oligomer, combining a first non-liquid reagent including at least one amplification oligomer with the first solvent and a first sample to form a first reaction mixture, combining a second non-liquid reagent lacking an amplification oligomer with the solvent included in a vial of the second container and a second sample to form a second reaction mixture, performing first and second amplification reactions with the first and second reaction mixtures, and determining the presence or absence of one or more analytes in the first and second reaction mixtures.
A computer-implemented method for determining the amount of an analyte in a sample comprises associating a nucleic acid amplification assay defined at least partly by user-defined assay parameters to the sample. The assay is performed by dissolving a unit-dose reagent with a solvent, wherein the solvent includes one or more amplification oligomers adapted to amplify a region of the analyte and the reagent does not include an amplification oligomer for performing the assay. A reaction mixture, including the dissolved reagent and the sample, is exposed to a temperature condition and measurements of fluorescence indicative of an amount of amplification products formed during the exposing are collected. The measurements are assessed with a computer using data analysis parameters provided by the user to compute results indicative of the amount of the analyte in the sample.
The present application discloses a tomosynthesis system and method that combines high dose gain maps directly, or high-resolution components of high dose gain maps, with low resolution components of low dose gain maps at a plurality of imaging parameters, to produce high quality gain map efficiently at the plurality of imaging parameters, to perform gain corrections to x-ray images.
G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/58 - Testing, adjusting or calibrating thereof
9.
SYSTEM FOR IMPROVED TISSUE HANDLING AND IN LINE ANALYSIS OF THE TISSUE
A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
A61B 10/02 - Instruments for taking cell samples or for biopsy
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
10.
Method of Quantifying Polynucleotide Analytes from Dried Samples
Presented are methods, systems, and software products useful for determining the concentration of an analyte in a fluid specimen used to produce a dried sample, where the dried sample serves as a source of the analyte in a detection and quantification procedure. Particularly illustrated is the use of dried blood spots for quantifying a polynucleotide analyte.
C12Q 1/6865 - Promoter-based amplification, e.g. nucleic acid sequence-based amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
11.
DEVICES AND METHODS FOR REDUCING FLUID IN THE IMAGING FIELD OF A TISSUE HANDLING APPARATUS FOR IMPROVING BIOPSY SYSTEM IMAGING QUALITY
A tissue holder assembly for receiving and imaging severed tissue samples from a biopsy device includes a base and a cover removably attached to the base to define an interior, the base having one or more vacuum lumens in communication with the interior, the assembly further including a tissue tray removably and rotatably mounted in the interior, wherein a bottom of the tissue tray comprises a filter material that allows fluid to pass through. The cover has a tissue sample entry port formed therein and configured direct severed tissue samples and fluid aspirated therethrough into a respective tissue storage compartment of the tissue tray positioned under the tissue sample entry port, wherein the base includes a raised surface underlying at least a portion of the tissue tray circumferentially spaced apart from the tissue sample entry port when the cover is attached to the base.
A61B 10/02 - Instruments for taking cell samples or for biopsy
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
12.
EVAPORATION-LIMITING INSERTS FOR REAGENT CONTAINERS AND RELATED METHODS OF USE
An insert for a liquid-holding container includes a body comprising a wall, open first and second ends, and a lumen extending from the open first end to the open second end. A plurality of first openings are formed in the wall, each of the first openings defining an area, and one or more second openings are formed in the wall, each of the one or more second openings defining an area that is greater than the area defined by any of the first openings. The first openings are arranged in a first row of at least three first openings in axial alignment and a second row of at least three first openings in axial alignment. At least one of the one or more second openings is situated closer to the first end than any of the first openings, and each of the first and second openings is sized to permit the passage of a liquid.
B01F 23/00 - Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
B01F 29/30 - Mixing the contents of individual packages or containers, e.g. by rotating tins or bottles
B01F 31/22 - Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
B01F 35/511 - Mixing receptacles provided with liners, e.g. wear resistant or flexible liners
B01F 35/53 - Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
Disclosed are compositions, methods, and kits that can be used to Epstein-Barr virus (EBV) in a sample undergoing testing. Nucleic acids of EBV can be isolated, amplified and detected with specificity, and without interference from non-EBV organisms. In some embodiments, nucleic acids used for amplification are isolated from human blood, or blood products. Nucleic acid isolation, amplification and detection steps can all be carried out using an automated instrument.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
Methods and systems for providing multi-plane viewing of a digital image of a subject matter which do not require viewing multiple images taken at multiple image planes. Pseudo-focus images are generated from a flattened, merged image of a three-dimensional subject matter. The merged image is generated by merging a plurality of images taken at different focal planes of the subject matter which form a through-focus image stack. The merged image comprises the best focus pixels originating from different respective image planes. A depth map is also generated from the multiple images which associates each best focus pixel with a pixel depth value. A plane of interest (POI) is selected from the image planes. A pseudo-focus image is then generated using the merged image and pixel depth map by generating a blurred focus value for each best focus pixel based on the focus offset of each pixel from the POI.
A system and method for acquiring images of objects distributed within a specimen affixed to a surface of a slide, the specimen having an uneven height relative to the slide surface using a camera having an objective lens with an optical axis that forms a non-orthogonal angle with the surface of the slide, the method including acquiring a first plurality of images of a first linear portion of the specimen; evaluating a focus of objects within the linear portion of the specimen captured in the first plurality of images; and acquiring a second plurality of images of the first linear portion or of a second linear portion of the specimen different from the first, wherein a height of the objective lens relative to the slide surface is varied during acquisition of the second plurality of images based on the evaluated focus of the objects captured in the first plurality of images.
G02B 21/34 - Microscope slides, e.g. mounting specimens on microscope slides
G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
H04N 23/959 - Computational photography systems, e.g. light-field imaging systems for extended depth of field imaging by adjusting depth of field during image capture, e.g. maximising or setting range based on scene characteristics
16.
AI SYSTEM FOR PREDICTING READING TIME AND READING COMPLEXITY FOR REVIEWING 2D/3D BREAST IMAGES
Examples of the present disclosure describe systems and methods for predicting the reading time and/or reading complexity of a breast image. In aspects, a first set of data relating to the reading time of breast images may be collected from one or more data sources, such as image acquisition workstations, image review workstations, and healthcare professional profile data. The first set of data may be used to train a predictive model to predict/estimate an expected reading time and/or an expected reading complexity for various breast images. Subsequently, a second set of data comprising at least one breast image may be provided as input to the trained predictive model. The trained predictive model may output an estimated reading time and/or reading complexity for the breast image. The output of the trained predictive model may be used to prioritize mammographic studies or optimize the utilization of available time for radiologists.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G06Q 10/0631 - Resource planning, allocation, distributing or scheduling for enterprises or organisations
G06Q 10/0639 - Performance analysis of employeesPerformance analysis of enterprise or organisation operations
G06Q 10/1093 - Calendar-based scheduling for persons or groups
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
17.
UPRIGHT X-RAY BREAST IMAGING WITH A CT MODE, MULTIPLE TOMOSYNTHESIS MODES, AND A MAMMOGRAPHY MODE
A multi-mode system and method for imaging a patient's breast with x-rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.
G09G 5/377 - Details of the operation on graphic patterns for mixing or overlaying two or more graphic patterns
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
G06T 7/30 - Determination of transform parameters for the alignment of images, i.e. image registration
A method of generating images of a specimen that includes triggering a source of electromagnetic radiation to emit a beam of electromagnetic radiation along an axis through a tissue specimen and towards an imaging detector, generating at least one image with the received beam at the imaging detector, and superimposing, into or adjacent the at least one image by a system controller, a set of graphical indications that convey portions of a patient's body from which respective portions of the specimen were assumed to have been excised.
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
G06V 10/24 - Aligning, centring, orientation detection or correction of the image
Method of preparing a biological sample appropriate for use in a subsequent in vitro nucleic acid amplification reaction. A biological sample is combined with an alkaline composition that lyses cells and denatures DNA to create a first liquid composition. The first liquid composition is then mixed with a buffer, a detergent, and a solid support that captures DNA to create a second liquid composition. The buffer, detergent, and solid support can be delivered as components of a single reagent. Captured DNA strands can be used as templates in subsequently performed nucleic acid amplification and detection reactions with improved sensitivity.
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Systems and methods for generating and using customized hanging protocol for the display of medical images. The methods may include receiving an indication to create a first hanging step of the hanging protocol, displaying a workspace having a plurality of viewports for displaying medical images, and displaying a plurality of building blocks corresponding to different types of medical images. The method may also include receiving a selection of a first building block in the plurality of building blocks, wherein the first building block corresponds to a first type of medical image, and receiving an indication of a location in the workspace for the first building block to be placed. Based on the indication of the location in the workspace for the first building block, one or more of the plurality of viewports is filled with the first building block.
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
G06F 3/04845 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range for image manipulation, e.g. dragging, rotation, expansion or change of colour
G06F 3/04886 - Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures by partitioning the display area of the touch-screen or the surface of the digitising tablet into independently controllable areas, e.g. virtual keyboards or menus
22.
LIGHT SOURCE FOR AN IMAGING SYSTEM AND METHODS OF THE SAME
An imaging system includes a gantry and a compression system coupled to the gantry and rotatable relative to the gantry. The compression system includes a compression paddle, a support platform, and an x-ray receptor disposed below the support platform. An x-ray tube head is coupled to the gantry and includes an x-ray source and a light source. The x-ray tube head is independently rotatable relative to the gantry and the compression system. The light source is configured to generate at least a first light type and a different second light type directed towards the support platform. The second light type being mapped to an x-ray field of the x-ray source, and the generated second light type is based on a tilt angle of the x-ray tube head relative to the support platform and a compression force of the compression paddle.
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/40 - Arrangements for generating radiation specially adapted for radiation diagnosis
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A biopsy system driver includes a motor having a rotatable output shaft, a support structure, a drive shaft, an elongate lead screw and a biopsy instrument drive member. The drive shaft is rotatably coupled to the support structure and includes or is otherwise operatively connected to the motor output shaft such that activation of the motor rotates the drive shaft. The elongate lead screw is coupled to the drive shaft such that rotation of the drive shaft rotates the lead screw about an axis of the lead screw. The lead screw is axially translatable relative to the drive shaft and to the support structure. The biopsy instrument drive member is threadably coupled to the lead screw such that rotation of the lead screw causes axial translation of one of the lead screw and biopsy instrument drive member relative to the other one and to the support structure.
A system and method for acquiring images of objects distributed within a specimen affixed to a surface of a slide, the specimen having an uneven height relative to the slide surface using a camera having an objective lens with an optical axis that forms a non-orthogonal angle with the surface of the slide, the method including acquiring a first plurality of images of a first linear portion of the specimen; evaluating a focus of objects within the linear portion of the specimen captured in the first plurality of images; and acquiring a second plurality of images of the first linear portion or of a second linear portion of the specimen different from the first, wherein a height of the objective lens relative to the slide surface is varied during acquisition of the second plurality of images based on the evaluated focus of the objects captured in the first plurality of images.
G02B 21/34 - Microscope slides, e.g. mounting specimens on microscope slides
G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
H04N 23/959 - Computational photography systems, e.g. light-field imaging systems for extended depth of field imaging by adjusting depth of field during image capture, e.g. maximising or setting range based on scene characteristics
25.
SYSTEM FOR READING MACHINE-READABLE LABELS ON SAMPLE RECEPTACLES
A system including a housing, a sample rack for holding a plurality of sample receptacles, and a reader for reading two-dimensional machine-readable labels associated with the plurality of sample receptacles as the sample rack moves between first and second positions within the housing. The system further includes a processing and control unit adapted to decode the two-dimensional machine-readable labels read by the reader and to associate each of the decoded two-dimensional machine-readable labels with an associated sample receptacle based on a measured position of the sample rack when the two-dimensional machine-readable label was read.
G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
26.
RECEPTACLE TRANSPORT SYSTEM FOR AN ANALYTICAL SYSTEM
A receptacle delivery system for an instrument of a plurality of instruments comprises a carriage supporting a puck. The carriage is configured to move with the puck from a first location to a second location within the instrument. The first location is a location where a receptacle supported by a carrier is positioned to be transferred to the puck supported by the carriage, and the second location being a location where the receptacle seated in the puck is positioned so that fluid from the receptacle can be drawn into a tip associated with a fluid extraction device of the instrument.
A method of compressing a breast of a patient with a breast imaging system includes obtaining an x-ray area of the breast of the patient. The x-ray area of the breast is compared to a data set, and a target force is based at least in part on the comparison is identified. A compressive force is applied to the breast, and is based at least in part on the target force. The breast is imaged with the breast imaging system.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
The present disclosure relates to compositions and methods, and related systems, products and kits, for performing temperature-dependent multiplex invasive cleavage assays, where a plurality of target nucleic acids are detected and distinguished from each other in a procedure using only a single fluorescent moiety as the reporter, and single channel fluorescence detection. In some embodiments, at least one of the plurality of target nucleic acids is an amplified nucleic acid, where progress in a thermal cycling amplification reaction is monitored as a function of time (i.e., real-time amplification).
Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
31.
METHODS FOR LOCATING PASSIVE INTEGRATED TRANSPONDER TAGS, AND DEVICES AND SYSTEMS INCORPORATING SAME
A method for locating a passive integrated transponder (PIT) tag embedded in tissue includes moving a reading device relative to an area of interest in the tissue. The reading device includes a probe having a coil at a distal end thereof. The coil is configured to transmit a signal resonating at a frequency of the PIT tag embedded within the tissue. The method also includes receiving one or more radio frequency (RF) signals with the reading device and determining whether at least one of the one or more RF signals is a radio frequency identification (RFID) signal transmitted by the PIT tag embedded within the tissue. The method further includes generating an indication of a presence and/or location of the PIT tag only when a RFID signal transmitted by the PIT tag embedded within the tissue is detected.
A61B 5/06 - Devices, other than using radiation, for detecting or locating foreign bodies
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A method for the display of medical images in a plurality of viewport configurations includes displaying a workspace on a computer display. A first viewport configuration of a looped series of viewport configurations is displayed in the workspace. A button is displayed with the first viewport configuration, where the button includes an icon representative of a next-in-series viewport configuration. At the button, an advance-to-next viewport selection is received. Based at least in part on receiving the advance-to-next viewport selection, the next-in-series viewport configuration of the looped series of viewport configurations is displayed in the workspace, where the next-in-series viewport configuration is different than the first viewport configuration. The button is displayed with the next-in-series viewport configuration, the button now including an icon representative of a subsequent viewport configuration different than the next-in-series viewport configuration.
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
G06F 3/0481 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
G06F 3/04845 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range for image manipulation, e.g. dragging, rotation, expansion or change of colour
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Specimen collection kit comprised of a solution for
collecting and transporting a sample for scientific research
purposes. Specimen collection kit comprised of a swab and solution for
collecting and transporting a sample for medical purposes. Scientific research specimen collection devices in the
nature of a swab and collection tube for the collection of
respiratory specimens. Medical specimen collection devices in the nature of a
collection tube for the collection of respiratory specimens.
34.
SYSTEM AND METHOD FOR TARGETED OBJECT ENHANCEMENT TO GENERATE SYNTHETIC BREAST TISSUE IMAGES
A method for processing breast tissue image data includes obtaining image data of a patient's breast tissue, processing the image data to generate a set of image slices, the image slices collectively depicting the patient's breast tissue; feeding image slices of the set through each of a plurality of object-recognizing modules, each of the object-recognizing modules being configured to recognize a respective type of object that may be present in the image slices; combining objects recognized by the respective object-recognizing modules to generate a synthesized image of the patient's breast tissue; and displaying the synthesized image.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A tissue removal device includes a housing, an outer tube having a distal portion configured for transcervical insertion into a uterus, an inner tube slidably disposed within the outer tube lumen, a vacuum generation chamber disposed within the housing, a movable piston slidably disposed in the vacuum generation chamber, a collection chamber, a manual actuator moveably coupled to the housing and operatively coupled to the piston, and proximal and distal one-way valves. The outer tube has an outer tube lumen, a tissue in-take opening proximate a distal end thereof, and a proximal end coupled to the housing. The inner tube has an inner tube lumen extending from an open inner tube distal end to an open inner tube proximal end, the open inner tube distal end comprising a cutting edge configured to sever intrauterine tissue extending through the tissue in-take opening in the outer tube.
A61B 10/02 - Instruments for taking cell samples or for biopsy
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 17/42 - Gynaecological or obstetrical instruments or methods
A multiplexed nucleic acid amplification and detection system useful for detecting the presence of multiple specific nucleic acid sequences or single nucleotide polymorphisms (i.e., “SNPs”) in a temperature-dependent fashion using only a single fluorescence detection channel of a nucleic acid analyzer. The technique can be carried out using standard PCR instrumentation equipped for fluorescence detection or monitoring.
An x-ray breast imaging system includes a breast support platform including an x-ray receptor, and an x-ray tube head. The x-ray tube head includes an x-ray source configured to emit an x-ray beam in a direction towards the x-ray receptor, and a collimator. A filter assembly including a plurality of filter slots selectively positionable adjacent to the collimator, and a specimen imaging filter disposed within a slot of the plurality of filter slots. The specimen imaging filter includes at least one aperture defined therein. The specimen imaging filter also blocks a portion of the emitted x-ray beam so that the at least one aperture defines a path of the emitted x-ray beam towards the x-ray receptor.
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/04 - Positioning of patientsTiltable beds or the like
A multiplexed nucleic acid amplification and detection system useful for detecting the presence of multiple specific nucleic acid sequences or single nucleotide polymorphisms (i.e., “SNPs”) in a temperature-dependent fashion using only a single fluorescence detection channel of a nucleic acid analyzer. The technique can be carried out using standard PCR instrumentation equipped for fluorescence detection or monitoring.
A multiplexed nucleic acid amplification and detection system useful for detecting the presence of multiple specific nucleic acid sequences or single nucleotide polymorphisms (i.e., “SNPs”) in a temperature-dependent fashion using only a single fluorescence detection channel of a nucleic acid analyzer. The technique can be carried out using standard PCR instrumentation equipped for fluorescence detection or monitoring.
Provided herein are compositions, kits, and methods for detecting at least one of a C. difficile tcdA, tcdB, tcdC, cdtA, or cdtB nucleic acid in a sample. In some embodiments, one or more alleles of tcdC such as 117del tcdC or 184T tcdC are detected.
C12Q 1/6827 - Hybridisation assays for detection of mutation or polymorphism
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
41.
LABORATORY AUTOMATED SYSTEMS FOR TRANSPORTING SAMPLE RECEPTACLE CARRIERS
An apparatus is directed to transporting a sample receptacle carrier coupled to a sample containing receptacle. The apparatus includes a movable dock to support the sample receptacle carrier. The apparatus includes one or more magnets. Each magnet is coupled to the movable dock to magnetically couple with a magnetic portion of the sample receptacle carrier. The one or more magnets secure the sample receptacle carrier to the movable dock.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 1/14 - Suction devices, e.g. pumpsEjector devices
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A multi-faceted soft tissue piercing element includes three distal planar cutting edges converging to form a sharp, distal point of the tissue piercing element. Each distal cutting edge forms a first angle with respect to a central longitudinal axis of the tissue piercing element. The tissue piercing element also includes three proximal planar cutting edges. Each proximal cutting edge extends proximally from a respective one of the three distal planar cutting edges. Each proximal cutting edge forms a second angle relative to the central longitudinal axis of the tissue piercing element. The second angle is larger than the first angle.
A system and method using an inflatable jacket over the compression paddle of a mammography and/or tomosynthesis system to enhance imaging and improve patient comfort in x-ray breast imaging.
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A bracket body releasably secures a compression element to the compression arm of a breast imaging system. A pair of parallel lateral arms extends from a rigid frame which extends from the bracket. A span connects the ends of the lateral arms opposite the bracket and a flexible membrane extends from the span towards the bracket body.
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
45.
COMPOSITIONS FOR DETECTING BORDETELLA PARAPERTUSSIS NUCLEIC ACID
Disclosed are nucleic acid oligomers, including amplification oligomers and detection probes, for detection of Bordetella pertussis and Bordetella parapertussis nucleic acid. Also disclosed are methods of specific nucleic acid amplification and detection using the disclosed oligomers, as well as corresponding reaction mixtures and kits.
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
C12Q 1/6816 - Hybridisation assays characterised by the detection means
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Biological assays and kits for use in fields of biological and diagnostic testing for industrial, scientific and research use; in vitro diagnostic reagents for scientific purposes; diagnostic preparations for in vitro testing for scientific use
(2) Clinical diagnostic reagents; medical diagnostic reagents and assays for testing of body fluids; medical diagnostic assay kits comprised of medical diagnostic reagents and assays for detecting protein levels; diagnostic kits comprising diagnostic reagents, preparations and substances for medical purposes, namely detecting protein levels; reagents for use in diagnostic tests for medical purposes
(3) Downloadable digital content in the form of electronic publications of booklets; downloadable computer software for interpreting, displaying, managing, and sharing healthcare information, namely, test results from in vitro diagnostic devices; diagnostic biomolecule detection devices for scientific research purposes; in vitro diagnostic devices, not for medical use
(4) Medical diagnostic apparatus for detecting biomarkers in body fluids; diagnostic test apparatus to detect protein levels; diagnostic biomolecule and DNA sequence detection devices for clinical medical purposes; diagnostic biomolecule and DNA sequence readers of biomolecule and DNA sequence testing results for clinical medical use; medical diagnostic apparatus for detecting protein levels
47.
ANTHROPOMETRY BY TWO-DIMENSIONAL RADIOGRAPHIC IMAGING
In some examples, anthropometric parameters of a subject are ascertained from radiographic image data. Radiograph image data is transformed to a representation of a lower dimensionality than the dimensionality of the image data by an machine learning processor. The representation of the radio graph image data is mapped to anthropometric parameters, directly or first to an intermediate three-dimensional optical image of the subject, and then from the intermediate three-dimensional optical image to anthropometric parameters.
G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
A biopsy device includes an elongated housing containing a stylet hub and a cannula hub. Each of the stylet and cannula hubs are movable between a proximal, armed position, and a distal, fired position. Each of the stylet hub and the cannula hub have a strike configured to retain the respective hub in its proximal, armed position. An arming member is moveably mounted to the housing and configured to move the stylet and cannula hubs to their respective proximal, armed positions. The housing includes a first deflectable wall portion, and when the stylet hub is in the distal fired position and the cannula hub is in the proximal, armed position, a portion of the stylet hub is positioned between the cannula strike and the first deflectable wall portion, enabling release of the cannula hub from its proximal, armed position by actuation of the first deflectable wall portion.
A system and method of analysis for medical image data. An image of breast tissue is received, a region of interest (ROI) in the image is identified based on tissue characteristics, and a query image is defined. A hierarchy of lesion data is retrieved, the hierarchy being formed based on one or more relationships among a plurality of images, and the query image is positioned within the hierarchy of lesion data based on the tissue characteristics. A position of the query image within the hierarchy of the lesion database is determined, identifying one or more neighbor images of the query image from among the plurality of images based on the position, and statistics associated with one or more neighbor images are retrieved. Analytics associated with the query image based on the statistics are generated, and a graphic depicting the analytics is displayed.
G06V 10/25 - Determination of region of interest [ROI] or a volume of interest [VOI]
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
In some embodiments, a bioimpedance measurement apparatus includes a set of electrodes configured to be placed on respective skin portions of a subject; a temperature sensor probe configured to be placed on a respective skin portion of the subject; a moisture sensor probe configured to be placed on a respective skin portion of the subject; and an electronic module configured to determine an impedance between at least two of the plurality of electrodes, receive from the temperature probe a temperature signal and determine from the temperature signal a temperature of the skin portion the temperature sensor probe is placed on, receive from the moisture sensor probe a moisture signal and determine a moisture level of the skin portion the moisture sensor probe is placed on, and determine a bioimpedance of the subject based at least in part on the determined impedance, temperature, and moisture level.
Disclosed are nucleic acid oligomers, including amplification oligomers and detection probes, for detection of Bordetella pertussis and Bordetella parapertussis nucleic acid. Also disclosed are methods of specific nucleic acid amplification and detection using the disclosed oligomers, as well as corresponding reaction mixtures and kits.
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
C12Q 1/6816 - Hybridisation assays characterised by the detection means
52.
CAPACITY MEASURING DEVICES FOR CRYOGEN VESSELS, AND RELATED SYSTEMS AND METHODS
A cryogen delivery system includes a probe configured to deliver a cryogenic fluid to a treatment location, a cryogen inlet configured to interface with a cryogenic fluid supply vessel to transfer cryogenic fluid from the cryogenic fluid supply vessel to the probe, a support structure configured to position the cryogenic fluid supply vessel relative to the cryogen inlet, and a sensor coupled to the support structure. The sensor is configured to generate a signal indicative of a weight of a cryogenic fluid contained in the cryogenic fluid supply vessel. Devices and methods relate to cryogen delivery systems.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
G01G 17/04 - Apparatus for, or methods of, weighing material of special form or property for weighing fluids, e.g. gases, pastes
53.
AUTOMATED PROCESSING OF SAMPLES CARRIED IN SAMPLE CONTAINERS AND GROUPING SAMPLE CONTAINERS ACCORDING TO ASSAYS TO BE PERFORMED ON SAMPLES CONTAINED THEREIN
A system for processing samples includes a sample database storing identification information correlated with one or more open assays associated with each sample. A conveyance transports sample containers, an input module holds sample containers, and a transfer robot transfers containers from the input module to the conveyance. An input scanner detects the machine-readable identification information on each sample container. At least one analyzer is configured to perform one or more functional assays on sample extracted from a sample container. A system controller is programmed to cause the transfer robot to transfer containers from the input module to the conveyance before scanning the machine-readable identification information and before identifying the one or more open assays associated with the sample container. The controller activates the input scanner to scan the machine-readable identification information as the sample container passes the input scanner and to access the sample database and identify one or more open assays for each sample container based on the identification information detected by the input scanner.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A station for tomotactic-guided biopsy in prone includes a table with an aperture, and a tomosynthesis imaging system. A biopsy gun can be mounted on a stage arm assembly disposed below the table. The imaging system and stage arm assembly can be independently rotated and linearly repositioned in one or more dimensions, thereby allowing the tomotactic scan axis to be located relative to a breast being imaged.
A61B 90/11 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/12 - Arrangements for detecting or locating foreign bodies
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 10/02 - Instruments for taking cell samples or for biopsy
A61B 10/04 - Endoscopic instruments, e.g. catheter-type instruments
55.
JIG FOR POSITIONING AND SECURING A FIRST CONSOLE WITH RESPECT TO A SECOND CONSOLE
A jig assembly for connecting first and second consoles with predefined relative positioning includes first and second positioning pins attached or attachable to the first console and a positioning connection bracket attached or attachable to the second console and including a longitudinal span and first and second transverse legs including first and second pin recesses at respective free ends thereof. The first and second pin recesses receive the first and second positioning pins, respectively, when the first and second consoles are moved laterally toward each other. The first and second transverse legs may be attached to the first console with a first and second leg attachment brackets, respectively. The first and second positing pins and the first and second leg attachment brackets may be fixed with respect to the first console by attachment to a mounting rail that is fixed to the first console.
Disclosed are methods for selectively isolating a microbial cell analyte (e.g., a nucleic acid) from a sample containing or suspected of containing mammalian cells. The selective isolation method includes selective lysis of the mammalian cells and filtration of the resulting lysate through a filter that retains intact microbial cells, followed by release of the retained microbial cells from the filter. The microbial cells are then collected from the filter using reverse-flow elution or aspiration, and the collected microbial cells are lysed to release the analyte from the intact cells. The isolated analytes may be analyzed using a suitable assay depending on the type of analyte molecule.
Systems and corresponding methods transfer liquid sample from a first container having a cap with a sample collection swab coupled thereto to a second container having a cap without such sample collection swap coupled thereto. Other systems and corresponding methods remove a cap having no sample collection swab coupled thereto from a first container and remove a cap having a sample collection swab coupled thereto from a second container containing a liquid sample. The cap with the sample collection swab coupled thereto is then secured to the first container and the cap having no sample collection swap coupled thereto is then secured to the second container.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
Techniques for patient positioning quality assurance prior to mammographic image acquisition are described. A system may include an x-ray source configured to expose human tissue to radiation. An x-ray detector module may be configured to detect the radiation and generate a pre-diagnostic image of the human tissue. A position analysis module may be configured to receive the pre-diagnostic image and determine whether the human tissue is positioned correctly based upon one or more predefined positioning criteria. A non-transitory computer-readable storage medium may be configured to store the results of the positional analysis module determination. A display may be configured to display the determination of the position analysis module within a user interface. Other embodiments are described and claimed.
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/04 - Positioning of patientsTiltable beds or the like
59.
TRAY FOR TRANSFERING SOLID REAGENTS TO A MULTI-WELL CARTRIDGE
A tray for transferring a plurality of solid reagents to a multi-well cartridge, the tray including a top surface having a plurality of depressions formed therein, each depression being configured to receive and hold a single one of the solid reagents, and a barrier wall projecting above and substantially surrounding the top surface, where the barrier wall is discontinuous at a first end of the tray.
Methods and systems providing guidance for operation of a biopsy needle based on ultrasonic imaging. Ultrasonic waves are emitted and detected by a ultrasonic transducer to generate image data. A biopsy needle is identified within the generated image data, and the biopsy needle may be in a pre-fire configuration. Based on the identification of the biopsy needle, the methods and systems may determine a predicted location of the biopsy needle based at least in part on biopsy needle properties. The predicted location of the biopsy needle may be the predicated location of the biopsy needle in its post-fire configuration. At least one indicator may be displayed indicating the determined predicted location.
A61B 34/00 - Computer-aided surgeryManipulators or robots specially adapted for use in surgery
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
G01S 7/52 - Details of systems according to groups , , of systems according to group
G01S 15/89 - Sonar systems specially adapted for specific applications for mapping or imaging
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A mechanism for positioning a fluid container supported on a movable carrier at a predetermined location comprises a container positioning ramp located adjacent to a portion of the moveable carrier and a container hold down arm. The container positioning ramp is configured to be contacted by a bottom portion of a container supported on the movable carrier when the movable carrier moves the container to the predetermined location. The container hold down arm is configured for selective movement relative to the container positioned at the predetermined location and is configured to contact a top portion of the container positioned at the predetermined location and push the container down so that the bottom portion of the container maintains contact with the container positioning ramp.
B65G 29/00 - Rotary conveyors, e.g. rotating discs, arms, star-wheels or cones
B65G 47/84 - Star-shaped wheels or devices having endless travelling belts or chains, the wheels or devices being equipped with article-engaging elements
G01F 23/263 - Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring variations of capacity or inductance of capacitors or inductors arising from the presence of liquid or fluent solid material in the electric or electromagnetic fields by measuring variations in capacitance of capacitors
A sample receptacle transporting carrier includes a base defining a recess for receiving a bottom end of the sample receptacle. The carrier also includes a plurality of resilient wire fingers affixed to and extending upward from the annular support. The fingers are configured to retain the bottom end of the sample receptacle within the recess of the base and to maintain the sample receptacle in an upright orientation. Each of the wire fingers includes a first segment adjacent to the base, a linear second segment joined to the first segment by a first angled portion, and a linear third segment joined to the second linear segment by a second angled portion. The third segment length is greater than the second segment length. The third segment of each finger is configured to contact the bottom end of the receptacle as the receptacle is inserted into the carrier. And the third segment and the vertical axis of the carrier form an angle between about 40° and about 50°.
A system for disposing of spent containers comprises a retainer cage disposed over a waste opening. The retainer cage comprises opposed, vertically-oriented first and second sides, an upper retainer bar and a lower retainer bar extending laterally from the first side of the retainer cage toward the second side, and a container gripper. The retainer bars are vertically spaced from one another and extend across a portion of the width of the retainer cage leaving a gap between the second side and terminal ends of the retainer bars, and the gap between the retainer bars and the second side is configured to permit a container to be inserted through the gap. The gripper is configured to hold the container, insert the container through the gap to a position between the first and second sides, and move to a position whereby the gripper is positioned between the vertically-spaced retainer bars and the container is located behind the retainer bars.
B65G 29/00 - Rotary conveyors, e.g. rotating discs, arms, star-wheels or cones
B65G 47/84 - Star-shaped wheels or devices having endless travelling belts or chains, the wheels or devices being equipped with article-engaging elements
G01F 23/263 - Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring variations of capacity or inductance of capacitors or inductors arising from the presence of liquid or fluent solid material in the electric or electromagnetic fields by measuring variations in capacitance of capacitors
A mechanism for holding and moving a plurality of containers includes a carousel configured to be rotatable about a vertically-oriented axis of rotation, and the carousel includes a plurality of container-holding pockets arranged circumferentially around an outer periphery of the carousel. Each container includes a vertically-oriented groove formed on each of opposed sides of the container. Each container-holding pocket is open at the outer periphery of the carousel to permit a container to be withdrawn out of the pocket in a radial direction with respect to the axis of rotation, and each container-holding pocket includes retention clips configured to engage the grooves formed on the container to removably retain the container within the container pocket.
B65G 29/00 - Rotary conveyors, e.g. rotating discs, arms, star-wheels or cones
B65G 47/84 - Star-shaped wheels or devices having endless travelling belts or chains, the wheels or devices being equipped with article-engaging elements
G01F 23/263 - Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring variations of capacity or inductance of capacitors or inductors arising from the presence of liquid or fluent solid material in the electric or electromagnetic fields by measuring variations in capacitance of capacitors
A tube arm assembly is rotatably connected to the floor mounted gantry of a breast imaging system. A support arm connected to the tube arm assembly can be independently rotated and positioned in a first angle, second angle, and a level position. A compression arm is configured to support a breast compression paddle and is linearly positionable on the support arm. Display screens and a sensor are disposed on an upper surface of the compression arm. Based on a signal received from the sensor, a controller is configured to change the read-ready orientation of each arm display.
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
67.
METHOD AND SYSTEM FOR IMPROVING SPECIFICITY OF ANALYTE DETECTION USING REAL-TIME NUCLEIC ACID AMPLIFICATION
Methods and systems including programmed computers that can be used for improving nucleic acid analyte detection using real-time amplification and monitoring, where closely related nucleic acid sequences can be resolved from each other. In one embodiment, detection of target sequences differing from each other by a single nucleotide were resolved by applying a mathematical transformation. In another embodiment, two target sequences differing from each other by a single nucleotide were detected and resolved from each other using a labeled probe specific for only one of the two target sequences.
A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
Intrauterine devices and methods for facilitating deployment thereof using a bumper are disclosed. In one embodiment, an intrauterine device comprises a structure including a first central support member and a deployment mechanism coupled to the first central support member. The intrauterine device further comprises a bumper positioned at a distal end of a second central support member and at a more distal position relative to a distal end of the structure so as to prevent the distal end of the structure from contacting the fundus of the uterus of a patient during deployment of the deployment mechanism. In another embodiment, the intrauterine device comprises a bumper coupled to the deployment mechanism and configured to move from a more distal to a more proximal position relative to a distal end of the structure.
A61B 17/02 - Surgical instruments, devices or methods for holding wounds open, e.g. retractorsTractors
A61B 17/42 - Gynaecological or obstetrical instruments or methods
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Kits for detecting analyte polynucleotides and an internal control in a sample. Included in the kit are an internal control polynucleotide and amplification reagents to co-amplify a first analyte polynucleotide and the internal control. Also included are first and second hybridization probes, each having a label indistinguishable from the other. The probes are respectively capable of hybridizing with a first analyte amplicon and an internal control amplicon. The first and second labels are indistinguishable homogeneous labels.
Systems and methods for loading reagent pellets into wells of a cartridge include a pellet transfer head including vacuum nozzles corresponding to the number and arrangement of the wells of the cartridge, a pellet reservoir holding reagent pellets, a vision sensor system for performing various system vision checks, and vertical and horizontal carriage assemblies to effect relative movement between the transfer head, pellet reservoir, cartridge, and vision sensor system. The pellet transfer head may include downwardly-facing pressure ports to supply gas flow into the pellet supply reservoir to fluidize the supply of pellets and a static eliminator fan to eliminate or reduce static buildup among pellets in the reservoir. A pellet is drawn from the reservoir to each vacuum nozzle, and the vision sensor system confirms that a single, unbroken and undeformed pellet is positioned at each nozzle and then confirms transfer of a single pellet to each well.
This disclosure provides oligomers, combinations of oligomers, compositions, kits, uses, and methods for detecting a C1orf43 nucleic acid, such as C1orf43 mRNA, such as human C1orf43 mRNA, in a sample.
A cam-driven actuator for actuating valves of a microfluidic cartridge includes a plunger associated with each valve, a plunger guide plate having a plunger guide hole for each plunger, an actuating ball associated with each plunger and in contact with the associated plunger, a ball guide plate having a ball guide hole for each actuating ball; and a cam including a first surface and a cam recess. Each actuating ball is in contact with the cam and the cam is movable with respect to each actuating ball between (i) an engaged position at which the actuating ball is in contact with the first surface and the associated plunger is in an engaged position to close the associated valve, and (ii) a disengaged position at which the actuating ball is disposed within the cam recess and the associated plunger is in a disengaged position to open the associated valve.
Methods, systems, reaction mixtures, kits, apparatuses, and systems for monitoring nucleic acid amplification reaction mixtures for abnormalities. Exemplary methods include determining fluorescence-based values from fluorophore-containing nucleic acid amplification reaction mixtures and determining whether those values satisfy predetermined values or indicate abnormalities.
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C12Q 1/6848 - Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
Methods, systems, and computer readable media for monitoring fluorescence signals from a nucleic acid amplification reaction for abnormal fluorescence detection. Exemplary methods include determining fluorescence-based values from fluorophore-containing nucleic acid amplification reaction mixtures and determining whether those values satisfy predetermined thresholds and/or ranges or otherwise indicate abnormalities.
A mobile imaging system or mini C-arm with an increased range of motion is disclosed. The mini C-arm including a mobile base, a C-arm assembly, and an arm assembly for coupling the C-arm assembly and the mobile base. The arm assembly being coupled to the mobile base via a first joint assembly that enables the arm assembly to move relative to the mobile base about first and second axes of rotation. Thus, in use, the first joint assembly enables two degrees of motion—a first vertical pivoting or rotational movement and a second horizontal pivoting or rotational movement. The first joint assembly being coupled to the base via a horizontal axis of rotation that is located at a vertically fixed position so that the horizontal axis of rotation is positioned at a fixed height or distance from the base, and hence a fixed height or distance from the floor.
A specimen holding and positioning apparatus operable to substantially non-movably maintain a specimen (e.g., an excised tissue specimen) in a fixed or stable orientation with respect to the apparatus during imaging operations (e.g., x-ray imaging), transport (e.g., from a surgery room to a pathologist's laboratory), and the like for use in facilitating accurate detection and diagnosis of cancers and/or other abnormalities of the specimen.
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 33/483 - Physical analysis of biological material
Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
Methods, systems, computer readable media of monitoring for the introduction of one or more liquids into a reaction chamber. Exemplary methods include determining fluorescencebased values from fluorophore-containing nucleic acid amplification reaction mixtures and determining whether those values satisfy predetermined thresholds and/or ranges or otherwise indicate abnormalities.
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C12Q 1/6848 - Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Specimen collection kit comprised of a solution for collecting and transporting a sample for scientific research purposes.
(2) Specimen collection kit comprised of a swab and solution for collecting and transporting a sample for medical purposes.
(3) Scientific research specimen collection devices in the nature of a swab and collection tube for the collection of respiratory specimens.
(4) Medical specimen collection devices in the nature of a collection tube for the collection of respiratory specimens.
Breast securement devices for imaging systems are provided. The securement device can include a breast tray configured to support a patient's breast. In one example, one or more walls extend from the breast tray to receive the patient's breast. In another example, a pair of arms pivotably extend at least partially over the breast tray to receive the patient's breast therebetween. In still another example, a membrane covers the breast tray and the patient's breast and selectively couples to the breast tray via a suction force. In yet another example, a paddle includes a plurality of flexible fingers that contour to the patient's breast, or includes an array of pins that independently slide within of the paddle and contour to the patient's breast, or includes a bladder having non-Newtonian fluid. Additionally or alternatively, a sling may receive the patient's breast and support the breast from below.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A method of imaging a breast compressed with a paddle including a foam compressive element. The method emits an x-ray energy from an x-ray source towards the breast and the foam compressive element and a marker disposed adjacent the foam compressive element. The x-ray energy is emitted over a predetermined time period. The marker includes a physical characteristic. The x-ray energy is detected at a detector disposed opposite the breast from the x-ray source. An image of the compressed breast and the marker is generated based on the detected x-ray energy. The marker in the generated image includes an image characteristic associated with the physical characteristic. The image characteristic is compared to the physical characteristic. A signal is sent when the image characteristic deviates from the physical characteristic by a threshold.
A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A laboratory automated system includes a conveyor assembly, a dock that that is movable between first and second positions, a drive assembly for moving the dock between the first and second positons, and a diverter for diverting a sample receptacle carrier from the conveyor assembly to the dock. The dock includes a first carrier support portion having a planar surface for supporting the sample receptacle carrier as the dock moves between the first and second positions. The dock includes an upwardly extending second carrier support portion situated adjacent the first carrier support portion. The second carrier support portion has a contoured side surface. The dock includes one or more magnets fixedly contained within or disposed on the second carrier support portion to magnetically couple with a magnetic portion of the sample receptacle carrier.
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01N 1/14 - Suction devices, e.g. pumpsEjector devices
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
Oligomer nucleotides, compositions, methods, kits, and uses are provided for detecting or quantifying a human polyomavirus BK virus (BKV) nucleic acid, e.g., using nucleic acid amplification and hybridization assays.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/12 - Arrangements for detecting or locating foreign bodies
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
A61B 10/02 - Instruments for taking cell samples or for biopsy
A61B 90/11 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
A61B 90/17 - Fixators for body parts, e.g. skull clampsConstructional details of fixators, e.g. pins for soft tissue, e.g. breast-holding devices
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Systems and methods for projecting a visual indicator onto a breast are disclosed. To better estimate an incision location or a location to apply an anesthetic, a visual indicator may be shown on the breast to indicate an intersection point of an interventional element and a surface of the breast. The visual indicator may be projected from a light source. The source may be positioned on a guidance system for an element near the element itself. The visual indicator may be moved based on a distance between the light and the surface of the breast (e.g., to counteract a parallax effect).
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
89.
BREAST COMPRESSION AND IMAGING SYSTEMS AND METHODS
A compression paddle with a plurality of markers is advanced towards a patient's breast which has been positioned on a support platform for an imaging procedure. An initial position of the compression paddle is detected relative to the support platform when a portion of the breast is contacted. An initial marker is identified which is associated with a feature of the breast when the compression paddle is in the initial position. A compression target marker is based at least in part on the initial position and the initial marker.
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/46 - Arrangements for interfacing with the operator or the patient
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
90.
METHODS AND DEVICES FOR TREATING PELVIC CONDITIONS
An ablation instrument comprises an elongate shaft having a cannula channel and a scope channel, and an electrode disposed in the cannula channel. The electrode is slidable between a first position in which a distal end of the electrode is contained within the cannula channel, and a second position in which the distal end of the electrode extends out of a distal opening of the cannula channel. The ablation instrument further comprises a distal head coupled to the elongate shaft and configured for contacting solid tissue.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
A method for masking a container in a computerized tomography (CT) image includes receiving a specimen secured in a container on a rotatable support surface and identifying the container. A mask corresponding to the container is determined. The specimen and container are rotated through a plurality of imaging angles. During rotation the specimen and container are imaged to obtain a set of 2D images and a 3D representation of the specimen and of the container are generated. A mask is applied to mask the 3D representation of the container. The resulting the 3D representation of the specimen is displayed.
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
G01N 23/083 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the radiation being X-rays
G01N 23/10 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the material being confined in a container, e.g. in luggage X-ray scanners
A curved compression element, such as a breast compression paddle, and imaging systems and methods for use with curved compression elements. A system may include a radiation source, a detector, and a curved compression element. Operations are performed that include receiving image data from the detector; accessing a correction map for the at least one compression paddle; correcting the image data based on the correction map to generate a corrected image data; and generating an image of the breast based on the corrected image data. The breast compression element generally has no sharp edges, but rather has smooth edges and transitions between surfaces. The breast compression paddle also includes a flexible material that spans a portion of a curved bottom surface of the breast compression paddle to define a gap. The flexible material may be a thin-film material such as a shrink wrap.
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/04 - Positioning of patientsTiltable beds or the like
A61B 6/58 - Testing, adjusting or calibrating thereof
93.
METHOD FOR RECEIVING AND STORING REAGENT PACKS IN AN INSTRUMENT
A method for performing an amplification reaction comprises the automated steps of combining a fluid sample together with one or more amplification reaction reagents in a reaction receptacle using a first automated pipettor, thereby forming a reaction mixture, transporting the reaction receptacle to a first, predetermined location of a centrifuge, subjecting the reaction mixture to centrifugation, after subjecting the reaction mixture to centrifugation, removing the reaction receptacle from a second, predetermined location of the centrifuge different from the first predetermined location and placing the reaction receptacle in a thermocycler, and in the thermocycler, subjecting the reaction mixture to one or more temperature cycles.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Recorded and downloadable computer software for use in medical imaging; Recorded and downloadable computer software for use in mammography imaging; recorded and downloadable computer software for use in the field of breast imaging Medical imaging apparatus; mammography imaging apparatus; medical imaging apparatus used in the field of breast health Non-downloadable computer software for use in medical imaging; non-downloadable software for use in mammography imaging; non-downloadable software for use in the field of breast imaging Medical imaging services; mammography imaging services; providing information in the field of breast health and medical imaging
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer hardware for use in the detection, diagnosis, and treatment of cancer; computer software for use in the detection, diagnosis, and treatment of cancer; laboratory apparatus for use in reviewing and analyzing cells; electronic imaging and image processing apparatus; computer software for storing, screening, reviewing, reproducing, transmitting, archiving, and processing medical data and images of cells; computer hardware and computer software for electronic imaging and image processing apparatus. Medical imaging apparatus and equipment; electronic image processing apparatus and equipment; slide processing apparatus and equipment; slide imaging apparatus and equipment.
96.
System and method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement
A method for processing breast tissue image data includes processing image data of a patient's breast tissue to generate a high-dimensional grid depicting one or more high-dimensional objects in the patient's breast tissue; determining a probability or confidence of each of the one or more high-dimensional objects depicted in the high-dimensional grid; and modifying one or more aspects of at least one of the one or more high-dimensional objects based at least in part on its respective determined probability or confidence to thereby generate a lower-dimensional format version of the one or more high-dimensional objects. The method may further include displaying the lower-dimensional format version of the one or more high-dimensional objects in a synthesized image of the patient's breast tissue.
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
Oligomer nucleotides, compositions, methods, kits, and uses are provided for detecting or quantifying a human polyomavirus BK virus (BKV) nucleic acid, e.g., using nucleic acid amplification and hybridization assays.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
Sample receptacles are automatically transferred from first and second storage areas of a storage module to a conveyor without passing over any other sample receptacle stored in the storage module. Receptacle holding positions in the first and second storage areas are arranged in rows and columns, and sample containers are transferred row-by-row or column-by-column, starting with sample container held closest to a first side of the first or second storage area. Receptacles transferred from the first storage area are transferred across the first side to the conveyor. Receptacles transferred from the second storage area are transferred across the first side into a first receptacle transport path between the first and second storage areas, and then to a second receptacle transport path across the first storage area, and then to the conveyor. To avoid passing a receptacle over another receptacle, receptacles are first removed from intervening holding positions between a respective holding position from which the receptacle is being transferred and the first side of the first or second storage area.
A multiplexed nucleic acid amplification and detection system useful for detecting the presence of multiple specific nucleic acid sequences or single nucleotide polymorphisms (i.e., “SNPs”) in a temperature-dependent fashion using only a single fluorescence detection channel of a nucleic acid analyzer. The technique can be carried out using standard PCR instrumentation equipped for fluorescence detection or monitoring.
The present application discloses a tomosynthesis system and method that combines high dose gain maps directly, or high-resolution components of high dose gain maps, with low resolution components of low dose gain maps at a plurality of imaging parameters, to produce high quality gain map efficiently at the plurality of imaging parameters, to perform gain corrections to x-ray images.
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
A61B 6/02 - Arrangements for diagnosis sequentially in different planesStereoscopic radiation diagnosis
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/58 - Testing, adjusting or calibrating thereof
G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
