Disclosed herein are radiopaque, reactive multi-arm polymers that comprise an iodine-containing core region, a plurality of polymer arms comprising a plurality of polymer segments linked to the iodine-containing core region, and a plurality of reactive moieties linked to the plurality of polymer segments. Also disclosed are methods of forming such radiopaque, reactive multi-arm polymers, systems for forming hydrogel compositions that comprise (a) such radiopaque, reactive multi-arm polymers and (b) multifunctional crosslinking compounds comprising a plurality of complementary reactive moieties that are reactive with the reactive moieties of the radiopaque, reactive multi-arm polymers, as well as reaction products of such systems and methods of treatment using such systems.
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. A seal is provided in the at least one fluid control device. In a first mode, the seal provides a seal between a fluid passageway and a fluid chamber of the fluid control device, to close the fluid control device. In a second mode, the seal is disengaged to open the fluid control device and allow fluid to flow between the fluid passageway and the fluid chamber. A seal retention device maintains a position of the seal when the fluid control device is open and fluid is flowing through the fluid control device.
A61F 2/48 - Operating or control means, e.g. from outside the body, control of sphincters
F16K 7/14 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
BOSTON SCIENTIFIC MEDICAL DEVICE LIMITED (Ireland)
Inventor
Davis, Ryan Robert
Tomar, Peeyush
Rogers, Carly
Himes, Matthew D.
Verma, Aman Kumar
Abstract
A delivery system for an occlusive implant includes a delivery sheath assembly and a hub assembly. The delivery sheath assembly includes a delivery sheath defining a delivery lumen adapted to accommodate an occlusive implant releasably secured to a core wire. A proximal fitting is secured to the delivery sheath. The hub assembly includes a hub body, a distal hub secured relative to the hub body and adapted to engage the proximal fitting of the delivery sheath assembly, a proximal hub secured to the hub body, and a side port coupled to hub body and adapted for flushing an interior of the delivery system. The delivery system includes one or more features that are adapted to limit relative rotation between the delivery sheath assembly and the hub assembly when the core wire is rotationally locked to the proximal hub.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
4.
AGGRESSIVE FEATURED CLIPS WITH IMPROVED TISSUE RETENTION
A system for treating tissue includes a capsule including a channel extending therethrough; first and second clip arms each extending from a proximal end to a distal end, the proximal ends being received within the channel of a capsule to be moved between an open tissue receiving configuration; and a closed tissue clipping configuration. The first clip arm includes a first tissue retention feature at a distal portion thereof configured to pierce through a target tissue when in the tissue clipping configuration and subsequently release the target tissue when the clip arms are moved to an at least partially open configuration. The second clip arm includes a second tissue retention feature at a distal portion thereof configured to pierce and retain the target tissue thereon when in both the closed tissue clipping configuration and the open tissue receiving configuration.
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.
A medical device may comprise a distal tip having a viewing element, a lighting element, and at least one feature configured to removably couple the distal tip to a shaft. The medical device may also comprise a working channel coupled to the distal tip and defining a central lumen configured to receive a tool. A wall of the working channel may define at least one additional lumen. The working channel may be configured to be removably inserted into the shaft. The medical device may also comprise at least one of a wire, a cable, or a conduit passing through the at least one additional lumen.
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
7.
ELECTROANATOMICAL MAPPING DEVICE WITH INTERNAL ELECTRODE
A medical system for creating a communication channel between two anatomical structures includes an outer member having a proximal portion and a distal portion, and a lumen extending from the proximal portion to the distal portion. At least a portion of the lumen includes an electrically conductive surface extending to a distal end of the distal portion. The system includes an inner member having a proximal portion and a distal portion. The inner member is configured to translate within the lumen and to deliver a therapy to target tissue. The inner member distal portion includes a conductive distal tip configured to electrically couple with the electrically conductive surface of the outer member. The inner member includes a proximal portion adapted to electrically couple the conductive distal tip to an auxiliary device.
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. A seal is provided in the at least one fluid control device. In a first mode, the seal provides a seal between a fluid passageway and a fluid chamber of the fluid control device, to close the fluid control device. In a second mode, the seal is disengaged to open the fluid control device and allow fluid to flow between the fluid passageway and the fluid chamber. A seal retention device maintains a position of the seal when the fluid control device is open and fluid is flowing through the fluid control device.
Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a sheath body and a distal tip region. A tip reinforcing member may be coupled to the distal tip region. The tip reinforcing member may define a plurality of distal arm segments. The distal arm segments are configured to shift between a first configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A linkage assembly for a medical device may comprise: a rotatable member configured to rotate about a rotation axis; a piston; and a connecting rod rotatably connected to the rotatable member and the piston and movable along a range. A first end of the range may correspond to an initial position of a distal member movable by the linkage assembly, and a second end of the range may correspond to a final position of a distal member. In a first configuration of the connecting rod, at the first end of the range, a proximal end of the connecting rod may be offset from a longitudinal axis by a first amount. In a second configuration of the connecting rod, at the second end of the range, the proximal end of the connecting rod may be offset from the longitudinal axis by a second amount.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A method is provided for enhancing video images in a medical device. The method includes receiving a first image frame and a second image frame from one or more image sensors. The first image sub-blocks are generated by dividing the first image frame. At least one curve to the first image sub-blocks are associated based on one or more look-up tables. A target in at least one of the first image sub-blocks is identified. Second image sub-blocks are generated by dividing the second image frame. At least one curve is associated to the second image sub-blocks based on the one or more look-up tables. The target is identified in at least one of the second image sub-blocks. Histogram enhanced images of the target in the first image sub-blocks and the second image sub-blocks are generated. A video image stream is generated based on the histogram enhanced images of the target.
Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a sheath body and a distal tip region. A tip reinforcing member may be coupled to the distal tip region. The tip reinforcing member may define a plurality of distal arm segments. The distal arm segments are configured to shift between a first configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
13.
CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS
The present disclosure pertains to systems for forming hydrogel compositions that comprise a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, wherein the system is configured to deliver the reactive polymer and the gold nanoparticles under conditions such that covalent crosslinks are formed between the reactive polymer and the gold nanoparticles. The present disclosure also pertains to methods of treatment that comprise administering to a subject a mixture that comprises a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, under conditions such that the reactive polymer and the gold nanoparticles crosslink after administration, and to radiopaque crosslinked hydrogel compositions that comprise a crosslinked reaction product of a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles.
This disclosure pertains to boronated hydrogel compositions, which comprise a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide. The disclosure also pertains to kits that comprise a reservoir, a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide disposed in the reservoir, and a device for administering the boronated hydrogel composition to a subject. The disclosure further pertains to methods of treatment that comprise applying or injecting a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide onto or into target cells of a subject and delivering neutron beam radiation to the target cells.
A medical device includes a catheter shaft including a distal region and an inflatable balloon that is secured to the distal region of the catheter shaft. The inflatable balloon has an outer surface and defines a centerline when inflated. A blade extends over and is secured to the outer surface, the blade having a cutting edge extending from a distal end of the blade to a proximal end of the blade, when the inflatable balloon is inflated, the cutting edge extends to a maximum distance measured relative to the centerline of the inflatable balloon at the distal end of the blade and a minimum distance measured relative to the centerline of the inflatable balloon of the medical device at the proximal end of the blade.
BOSTON SCIENTIFIC MEDICAL DEVICE LIMITED (Ireland)
Inventor
Davis, Ryan, Robert
Tomar, Peeyush
Rogers, Carly
Himes, Matthew, D.
Verma, Aman, Kumar
Abstract
A delivery system for an occlusive implant includes a delivery sheath assembly and a hub assembly. The delivery sheath assembly includes a delivery sheath defining a delivery lumen adapted to accommodate an occlusive implant releasably secured to a core wire. A proximal fitting is secured to the delivery sheath. The hub assembly includes a hub body, a distal hub secured relative to the hub body and adapted to engage the proximal fitting of the delivery sheath assembly, a proximal hub secured to the hub body, and a side port coupled to hub body and adapted for flushing an interior of the delivery system. The delivery system includes one or more features that are adapted to limit relative rotation between the delivery sheath assembly and the hub assembly when the core wire is rotationally locked to the proximal hub.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
Devices, systems, and methods for deploying a biliary stent. A biliary stent has lobes and creases to expand between contracted and expanded positions. The stent is delivered to a bile duct in a contracted position loaded on a shaft of a delivery device. When the shaft is retracted through the stent, wings on the shaft force the stent outward into the larger expanded position. In the expanded position, the creases form drainage channels to reduce blockage over the life of the stent.
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. The at least one fluid control device includes an auxiliary fluid control device that maintains a closed state of the valve in response to a fluctuation in pressure, or a pressure spike that would otherwise cause an unintentional opening of the fluid control device, and unintentional flow of fluid through the fluid control device.
A medical device may comprise a tube including: a proximal portion; and a distal portion having a slotted section with a plurality of slots formed therein. A proximalmost slot of the plurality of slots may have a first length in a circumferential direction about the tube. A distalmost slot of the plurality of slots may have a second length in the circumferential direction about the tube. The first length may be smaller than the second length. The medical device may further comprise a hub coupled to a proximal portion of the tube. Rotation of the hub may be configured to rotate the proximal portion of the tube about a longitudinal axis of the proximal portion of the tube.
An actuation mechanism for a medical device comprises: a rotatable member configured to rotate about a rotational axis and a spring, coupled directly or indirectly to the rotatable member. The spring is configured to move from a first configuration to a second configuration. In the first configuration, a longitudinal axis of the spring has a first angle with respect to a lever arm of the rotatable member. In the second configuration, a longitudinal axis of the spring has a second angle with respect to the lever arm of the rotatable member.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A polymeric material having a polyisobutylene polyurethane. The polyisobutylene having soft segments including a polyisobutylene diamine residue, and hard segments including bis-cyclic carbonate residue.
C08L 23/22 - Copolymers of isobutene; Butyl rubber
C08L 23/36 - Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers modified by chemical after-treatment by reaction with nitrogen-containing compounds, e.g. by nitration
22.
MULTI-ELECTRODE DEVICES, SYSTEMS, AND METHODS FOR MEDICAL PROCEDURES
A multi-electrode energy-delivering assembly configured to be delivered in a generally elongate delivery configuration. The multi-electrode energy-delivering assembly includes one or more spaced apart electrodes of a first polarity. The electrodes may be spaced apart axially and/or may be expanded apart from one another upon deployment. In some aspects, the electrodes may be electrically activated independently of one another.
A medical system for creating a communication channel between two anatomical structures includes an outer member having a proximal portion and a distal portion, and a lumen extending from the proximal portion to the distal portion. At least a portion of the lumen includes an electrically conductive surface extending to a distal end of the distal portion. The system includes an inner member having a proximal portion and a distal portion. The inner member is configured to translate within the lumen and to deliver a therapy to target tissue. The inner member distal portion includes a conductive distal tip configured to electrically couple with the electrically conductive surface of the outer member. The inner member includes a proximal portion adapted to electrically couple the conductive distal tip to an auxiliary device.
A medical device includes a shaft and a braided sheath. The braided sheath is coaxial with the shaft and at least extends along the shaft between a distal end of the shaft and a proximal end of the shaft. The braided sheath includes a braiding. The braiding includes a plurality of mechanical strands and at least one conductor configured to deliver energy to or convey signals to and from an electrical device positioned at or near the distal end of the shaft.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
25.
MEDICAL OPTICAL FIBER WITH INTRA-PROCEDURE RENEWABLE TIP
The present disclosure provides a medical optical fiber comprising a renewable distal end. The renewable distal end comprising several detachable segments where the detachable segments can be selectively and/or automatically detached to renew the distal most tip of the optical fiber.
A61B 18/26 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor for producing a shock wave, e.g. laser lithotripsy
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor
26.
ENDOLUMINAL SEALING DEVICES AND RELATED METHODS OF USE
A medical system includes a porous body positioned at a target site within a subject, a tube including a wall defining a tube lumen, where the tube is connected to the porous body at a first end of the tube, and a sealing device to seal the target site from a body lumen. When the sealing device seals the target site from the body lumen, the tube extends from the target site into the body lumen.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
27.
Apparatus and Methodology for Reshaping a Laser Beam
A laser system may include a laser resonator configured to emit an input laser beam having an elliptical cross-sectional shape. The laser system also may include first reflective device configured to reflect the input laser beam to produce a first reflected laser beam. The first reflective device may include a spherical surface for reflecting the input laser beam. The laser system also may include a second reflective device configured to reflect the first reflected laser beam to produce a second reflected laser beam. The laser system also may include a coupling device configured to focus the second reflected laser beam to produce an output laser beam. The coupling device may include a spherical surface for receiving the second reflected laser beam. The laser system also may include an optic fiber configured to transmit the output laser beam for emission of the output laser beam onto a target area.
Example medical stents are disclosed. An example stent includes a tubular framework including an inner surface, an outer surface and a lumen extending therethrough. Additionally, the stent includes a tissue ingrowth scaffold extending along a portion of the outer surface of the tubular framework, wherein the tissue ingrowth scaffold is spaced radially away from the outer surface of the tubular framework to define an expansion cavity therebetween and wherein the tissue ingrowth scaffold permits tissue ingrowth along a portion thereof. Further, the stent includes an expandable member positioned within at least a portion of the expansion cavity.
A61F 2/90 - Stents in a form characterised by wire-like elements; Stents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/844 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents folded prior to deployment
A61F 2/848 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
A61F 2/88 - Stents in a form characterised by wire-like elements; Stents in a form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
A61F 2/92 - Stents in the form of a rolled-up sheet expanding after insertion into the vessel
A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts
Devices, systems, and methods for a two-way valve assembly for a medical device. The two-way valve assembly has a knob seated within a valve body, two inlet passages leading to a suction source and a gas source, an outlet passage leading to an endoscope fluid channel, and an internal channel connecting one of the two inlet passages to the outlet passage. A spring presses the knob into the valve body to seal the openings along the channels and passages. Rotating the knob slides one or more guide pins on the knob along one or more guide grooves on the body and connects the other inlet passage to the outlet passage, such that the same endoscope fluid channel can be used both for suction, as in clearing fluid from within a patient, and delivering gas, as in insufflation.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
An actuation mechanism for a medical device comprises: a rotatable member configured to rotate about a rotational axis and a spring, coupled directly or indirectly to the rotatable member. The spring is configured to move from a first configuration to a second configuration. In the first configuration, a longitudinal axis of the spring has a first angle with respect to a lever arm of the rotatable member. In the second configuration, a longitudinal axis of the spring has a second angle with respect to the lever arm of the rotatable member.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and an electronic fluid control system to transfer fluid between the fluid reservoir and the inflatable member. The fluid control system includes at least one combination pump and valve device including a piezoelectric actuator.
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. The at least one fluid control device includes an auxiliary fluid control device that maintains a closed state of the valve in response to a fluctuation in pressure, or a pressure spike that would otherwise cause an unintentional opening of the fluid control device, and unintentional flow of fluid through the fluid control device.
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A multi-electrode energy-delivering assembly configured to be delivered in a generally elongate delivery configuration. The multi-electrode energy-delivering assembly includes one or more spaced apart electrodes of a first polarity. The electrodes may be spaced apart axially and/or may be expanded apart from one another upon deployment. In some aspects, the electrodes may be electrically activated independently of one another.
Bipolar or monopolar adjustable energy-delivering assemblies. The assemblies are configured for transluminal (e.g., endoscopic) delivery within a patient. A first energy-delivering member defines a first electrode portion formed of an electrically-conductive material so that energy may be delivered to the first energy-delivering member to create an energy field along the first electrode portion to apply to a target site within a patient. The first energy-delivering member may define a lumen therethrough allowing delivery of materials distally therethrough to a target site and/or allows materials from the target site to be aspirated proximally therethrough. Optionally, a second energy-delivering member and a second insulation member form a second electrode portion. Optionally, either or both electrode portions may be adjustable. Additionally or alternatively, the first electrode portion and the second electrode portion are adjustable with respect to each other.
An energy-delivering treatment system facilitating determination of various characteristics of a lesion and/or tissue at a treatment site, such as the size and/or location of the lesion; stiffness and/or elasticity of the tissue; impedance or resistance of the tissue (which may impact the form of energy such as electroporation and/or irreversible electroporation applied to the tissue); and/or the effects of a treatment applied to the lesion. Information gathered regarding the treatment site may be used to aid in predicting and measuring lesions, and/or in determining an appropriate treatment plan on a patient-by-patient basis. Markers may be used to facilitate locating of the treatment site after the energy-delivering assembly has been withdrawn from the treatment site.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
36.
DEVICES, SYSTEMS, AND METHODS FOR TUNNELING BETWEEN TISSUE LAYERS
An assembly and/or system having a cutting device configured to cut tissue, and an inflatable device configured for insertion into the cut tissue to further separate the cut tissue. The inflatable device may be wedge shaped to separate the cut tissue upon insertion into the cut. The inflatable device is inflatable and otherwise adjustable to separate the tissue to a medically indicated extent. For instance, the inflatable device may be moved axially with respect to the cutting device; and/or may be sheathed or unsheathed to adjust an exposed inflated length thereof; and/or may include two or more separately inflatable elements. The inflatable device thus may be used to achieve blunt tissue dissection after an initial cut is made into the tissue with a sharper instrument.
A medical device includes a shaft and a braided sheath. The braided sheath is coaxial with the shaft and at least extends along the shaft between a distal end of the shaft and a proximal end of the shaft. The braided sheath includes a braiding. The braiding includes a plurality of mechanical strands and at least one conductor configured to deliver energy to or convey signals to and from an electrical device positioned at or near the distal end of the shaft.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
The present disclosure pertains to systems for forming hydrogel compositions that comprise a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, wherein the system is configured to deliver the reactive polymer and the gold nanoparticles under conditions such that covalent crosslinks are formed between the reactive polymer and the gold nanoparticles. The present disclosure also pertains to methods of treatment that comprise administering to a subject a mixture that comprises a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, under conditions such that the reactive polymer and the gold nanoparticles crosslink after administration, and to radiopaque crosslinked hydrogel compositions that comprise a crosslinked reaction product of a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles.
The present disclosure provides a medical optical fiber comprising a renewable distal end. The renewable distal end comprising several detachable segments where the detachable segments can be selectively and/or automatically detached to renew the distal most tip of the optical fiber.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor
Devices, systems, and methods for a two-way valve assembly for a medical device. The two-way valve assembly has a knob seated within a valve body, two inlet passages leading to a suction source and a gas source, an outlet passage leading to an endoscope fluid channel, and an internal channel connecting one of the two inlet passages to the outlet passage. A spring presses the knob into the valve body to seal the openings along the channels and passages. Rotating the knob slides one or more guide pins on the knob along one or more guide grooves on the body and connects the other inlet passage to the outlet passage, such that the same endoscope fluid channel can be used both for suction, as in clearing fluid from within a patient, and delivering gas, as in insufflation.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/267 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the respiratory tract, e.g. laryngoscopes, bronchoscopes
41.
MICRO-FLUIDIC DEVICE COMBINING FUNCTIONS OF A PUMP AND A VALVE
An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and an electronic fluid control system to transfer fluid between the fluid reservoir and the inflatable member. The fluid control system includes at least one combination pump and valve device including a piezoelectric actuator.
Bipolar or monopolar adjustable energy-delivering assemblies. The assemblies are configured for transluminal (e.g., endoscopic) delivery within a patient. A first energy-delivering member defines a first electrode portion formed of an electrically-conductive material so that energy may be delivered to the first energy-delivering member to create an energy field along the first electrode portion to apply to a target site within a patient. The first energy-delivering member may define a lumen therethrough allowing delivery of materials distally therethrough to a target site and/or allows materials from the target site to be aspirated proximally therethrough. Optionally, a second energy-delivering member and a second insulation member form a second electrode portion. Optionally, either or both electrode portions may be adjustable. Additionally or alternatively, the first electrode portion and the second electrode portion are adjustable with respect to each other.
An energy-delivering treatment system facilitating determination of various characteristics of a lesion and/or tissue at a treatment site, such as the size and/or location of the lesion; stiffness and/or elasticity of the tissue; impedance or resistance of the tissue (which may impact the form of energy such as electroporation and/or irreversible electroporation applied to the tissue); and/or the effects of a treatment applied to the lesion. Information gathered regarding the treatment site may be used to aid in predicting and measuring lesions, and/or in determining an appropriate treatment plan on a patient-by-patient basis. Markers may be used to facilitate locating of the treatment site after the energy-delivering assembly has been withdrawn from the treatment site.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/0536 - Impedance imaging, e.g. by tomography
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
44.
DEVICES, SYSTEMS, AND METHODS FOR TUNNELING BETWEEN TISSUE LAYERS
An assembly and/or system having a cutting device configured to cut tissue, and an inflatable device configured for insertion into the cut tissue to further separate the cut tissue. The inflatable device may be wedge shaped to separate the cut tissue upon insertion into the cut. The inflatable device is inflatable and otherwise adjustable to separate the tissue to a medically indicated extent. For instance, the inflatable device may be moved axially with respect to the cutting device; and/or may be sheathed or unsheathed to adjust an exposed inflated length thereof; and/or may include two or more separately inflatable elements. The inflatable device thus may be used to achieve blunt tissue dissection after an initial cut is made into the tissue with a sharper instrument.
Medical devices and related methods useful for needle access during medical procedures are described. The medical device may include a needle and a handle coupled to the needle, wherein the handle includes a body comprising a radiolucent material, a first marker proximate a proximal end of the body and a second marker proximate a distal end of the body. Each of the first marker and the second marker may include a radiopaque material, and the first marker may have a shape complementary to the second marker to align a position of the needle relative to a subject when visualized by X-ray imaging.
A61B 6/12 - Devices for detecting or locating foreign bodies
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Devices, systems, and methods for deploying a biliary stent. A biliary stent has lobes and creases to expand between contracted and expanded positions. The stent is delivered to a bile duct in a contracted position loaded on a shaft of a delivery device. When the shaft is retracted through the stent, wings on the shaft force the stent outward into the larger expanded position. In the expanded position, the creases form drainage channels to reduce blockage over the life of the stent.
A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
In some aspects, the present disclosure pertains to methods of treating a tissue volume comprising (a) administering an implantable composition comprising a releasable membrane-active agent to a target site such that the membrane-active agent is locally released to the tissue volume and (b) performing irreversible, reversible and/or thermal treatment by application of a pulsed electric field to the tissue volume. In other aspects, the present disclosure pertains to embolic compositions that comprise releasable membrane-active agents.
A medical device (10) may comprise a tube (118) including: a proximal portion; and a distal portion having a slotted section with a plurality of slots (122) formed therein. A proximalmost slot of the plurality of slots may have a first length in a circumferential direction about the tube. A distalmost slot of the plurality of slots may have a second length in the circumferential direction about the tube. The first length may be smaller than the second length. The medical device may further comprise a hub (40) coupled to a proximal portion of the tube. Rotation of the hub may be configured to rotate the proximal portion of the tube about a longitudinal axis of the proximal portion of the tube.
This disclosure pertains to boronated hydrogel compositions, which comprise a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide. The disclosure also pertains to kits that comprise a reservoir, a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide disposed in the reservoir, and a device for administering the boronated hydrogel composition to a subject. The disclosure further pertains to methods of treatment that comprise applying or injecting a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide onto or into target cells of a subject and delivering neutron beam radiation to the target cells.
A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
Disclosed herein are radiopaque, reactive multi-arm polymers that comprise an iodine-containing core region, a plurality of polymer arms comprising a plurality of polymer segments linked to the iodine-containing core region, and a plurality of reactive moieties linked to the plurality of polymer segments. Also disclosed are methods of forming such radiopaque, reactive multi-arm polymers, systems for forming hydrogel compositions that comprise (a) such radiopaque, reactive multi-arm polymers and (b) multifunctional crosslinking compounds comprising a plurality of complementary reactive moieties that are reactive with the reactive moieties of the radiopaque, reactive multi-arm polymers, as well as reaction products of such systems and methods of treatment using such systems.
A polymeric material having a polyisobutylene polyurethane. The polyisobutylene having soft segments including a polyisobutylene diamine residue, and hard segments including bis-cyclic carbonate residue.
Medical devices and related methods useful for needle access during medical procedures are described. The medical device may include a needle and a handle coupled to the needle, wherein the handle includes a body comprising a radiolucent material, a first marker proximate a proximal end of the body and a second marker proximate a distal end of the body. Each of the first marker and the second marker may include a radiopaque material, and the first marker may have a shape complementary to the second marker to align a position of the needle relative to a subject when visualized by X-ray imaging.
A61M 25/06 - Body-piercing guide needles or the like
A61B 6/12 - Devices for detecting or locating foreign bodies
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
Pharmaceutical preparations in the nature of implantable
materials, namely, pliable, synthetic hydrogel for medical
and surgical purposes for the treatment of prostate cancer;
medical device consisting of a pre-polymerized hydrogel for
use in medical and surgical procedures for the treatment of
prostate cancer.
A left atrial appendage (LAA) ligation device is adapted for ligating the LAA via a trans-septal approach, the LAA including an ostium. The LAA ligation device includes a spiral ligation element extending from an end point disposed at a periphery of the spiral ligation element to a center point of the spiral ligation element, the spiral ligation element having a diameter defined by the periphery and a length defined between the periphery and the center point. A delivery device is adapted to releasably secure the spiral ligation element and to enable rotation of the spiral ligation device.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Medical devices and related methods are described, including a medical device that includes a shaft defining at least one working channel extending from a proximal end of the shaft to a distal end of the shaft along a longitudinal axis and a distal tip coupled to the shaft. The working channel may have a cross-sectional dimension that allows passage of an instrument therethrough. The distal tip may include a first arm and a second arm, the first arm being moveable relative to the second arm between a first configuration that obstructs a portion of the working channel and a second configuration that provides unobstructed access to the working channel, e.g., to allow the instrument to extend distal to the medical device.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
The present disclosure provides medical devices (400) such as self-expanding stents or tissue lumen stents with an overlapping layer. The medical devices can have a coating or cover disposed over all or a portion of the medical device. The overlapping layer define a doubled back portion at an end of the medical device that includes an elongate section (414) to provide dynamic movement of the end of the medical device relative to a central portion (408) of the medical device.
A61B 17/11 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for performing anastomosis; Buttons for anastomosis
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
57.
SYSTEMS FOR ACCELERATING HYDROLYSIS OF IMPLANTABLE MEDICAL DEVICES
Systems for hydrogel hydrolysis as well as methods for hydrogel hydrolysis are disclosed. An example system may include a syringe barrel having a needle connector disposed thereon. A hydrogel hydrolysis material may be disposed in the syringe barrel. The hydrogel hydrolysis material may be configured to be injected into a hydrogel formed in the body of a patient in order to accelerate the hydrolysis of the hydrogel.
A steerable catheter (10) includes an outer sheath defining an outer sheath lumen extending from a proximal region to a distal region (16). A push ring (22) is secured within the proximal region of the outer sheath lumen. A pull ring (24) is secured within the distal region of the outer sheath lumen. An inner shaft member (30) extends within the outer sheath lumen between the push ring (22) and the pull ring (24). A pair of push members (26a, 26b) extends through the outer sheath lumen and is secured to the push ring (22), each of the pair of push members defining a push member lumen extending therethrough. A pair of pull wires (28a, 28b) are secured to the pull ring (24), each of the pair of pull wires (28a, 28b) extending through one of the push member lumens.
Assistive medical accessories and methods for making and using assistive medical accessories are disclosed. An example assistive medical accessory may include a sterile drape configured for use with a medical device. The sterile drape may have a top surface. A visual indicator may be disposed along the top surface. The visual indicator may be configured to provide use information to a clinician using the medical device.
A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
61.
DEVICE AND METHOD FOR APPLYING A CINCH TO A SUTURE
Medical devices for applying a cinch to a suture and methods for making and using such devices are disclosed. An example medical device may include an elongated shaft including a proximal region and a distal region. The distal region may define a lumen having a lumen dimeter, and a distally facing end surface. The medical device may also include an outer cinch member defining a bore and having an outer surface defining a shoulder. An elongated inner shaft may extend through and be longitudinally movable within the lumen and the bore and including a distal end section. An inner cinch member may be engaged with the distal end section of the elongated inner shaft.
A61B 17/04 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for suturing wounds; Holders or packages for needles or suture materials
62.
SIDE BRANCH DETECTION FOR INTRAVASCULAR IMAGE CO-REGISTRATION WITH EXTRAVASCULAR IMAGES
The present disclosure provides devices and methods to identify locations of side branches in a series of intravascular images (e.g., a pre-treatment IVUS pullback, a post-treatment IVUS pullback, or the like) to assist with co-registering the IVUS images with an extravascular image (e.g., angiogram, or the like) or with another set of IVUS images. The present disclosure further provides devices and methods for training a machine learning (ML) model to infer side branch locations from IVUS images and an analytic algorithm for extracting frames from the IVUS images representing side branches.
Embodiments herein relate to a cryoablation probe including a pre-cooler fluid circuit; a working fluid circuit; a vacuum circuit; and a shaft. The shaft includes a supply tube and a return tube surrounding the supply tube. The return tube includes a first polymer layer, wherein the first polymer layer is configured to contain fluid from the working fluid circuit; a reinforcement layer, and a second polymer layer. Other embodiments are also included herein.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
64.
A SYSTEM AND METHOD FOR QUALITY ASSURANCE OF MEDICAL IMAGE SEGMENTATION
A method and system for reviewing contouring of medical images in a contouring system is described. The method comprising the steps of: providing at least one medical image showing structures to be contoured; generating a contour for a structure on the at least one medical image; determining if the generated contour conforms to guidelines for the structure being contoured; in response to the determining of conformity providing feedback about the quality of the contour; and continuing to generate the contour based on the provided feedback. A method and system for reviewing previously contoured medical images is also described.
A method and system for contouring an image for display is described. The method comprising: providing at least one image to be contoured; providing a window width parameter, W, and a window level parameter, L; displaying the medical image according the W,L parameters; performing the following steps: determining local image intensities of the at least one image for each position of the contour, as it is generated; determining if the parameters are suitable for each position of the contour on the image as it is generated; according to the determined local image intensity; if the parameters are not suitable, alerting the user that at least one of the parameters is not suitable for a most recently generated position on the contour; adjusting at least one of the—parameters to be suitable for the most recently generated position on the contour; and displaying the—image according to the adjusted settings.
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G06V 10/46 - Descriptors for shape, contour or point-related descriptors, e.g. scale invariant feature transform [SIFT] or bags of words [BoW]; Salient regional features
G06V 10/56 - Extraction of image or video features relating to colour
G06V 10/60 - Extraction of image or video features relating to illumination properties, e.g. using a reflectance or lighting model
66.
A SYSTEM AND METHOD FOR CONTOURING A MEDICAL IMAGE AND REVIEWING EXISTING CONTOURS
A method and system for contouring a medical image in a contouring system is described. The method comprising the steps of: providing at least one medical image to be contoured by a user; determining that the user has initiated contouring of a structure on the medical image; the contouring system determining the structure that is being or will be contoured; in response to the determination of the structure the system displaying guidance for the contouring of the determined structure; contouring the determined structure in accordance with the displayed guidance. A method and system for reviewing contours on a contoured medical image is also described.
Medical devices and related methods are described, including a medical device that includes a shaft defining at least one working channel extending from a proximal end of the shaft to a distal end of the shaft along a longitudinal axis and a distal tip coupled to the shaft. The working channel may have a cross-sectional dimension that allows passage of an instrument therethrough. The distal tip may include a first arm and a second arm, the first arm being moveable relative to the second arm between a first configuration that obstructs a portion of the working channel and a second configuration that provides unobstructed access to the working channel, e.g., to allow the instrument to extend distal to the medical device.
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
68.
SYSTEMS AND METHODS FOR PROCESSING ELECTRONIC MEDICAL IMAGES TO DETERMINE ENHANCED ELECTRONIC MEDICAL IMAGES
Systems and methods for processing electronic images from a medical device comprise receiving a first image frame and a second image frame from a medical device, and determining a region of interest by subtracting the first image frame from the second image frame, the region of interest corresponding to a visual obstruction in the first image frame and/or second image frame. Image processing may be applied to the first image frame and/or second image frame based on a comparison between a first area of the first image frame corresponding to the region of interest and a second area of the second image frame corresponding to the region of interest, and the first image frame and/or second image frame may be provided for display to a user.
A61B 18/26 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor for producing a shock wave, e.g. laser lithotripsy
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A navigation-assisting flexible elongate member, a navigation-assisting system, and a navigation-assisting method for use in navigating within a body to a treatment site. A navigation-assisting sensor, such as an optic fiber, an inductive sensor, a piezoelectric sensor, or a camera, is provided within the wall of the flexible elongate member, so as not to occupy space within a working channel defined by and through the flexible elongate member. When the distal end of the flexible elongate encounters an obstacle/another object (e.g., body tissue or a lumen wall), the navigation-assisting sensor generates a signal indicative of such encounter. Such signal is converted into information (such as by a control unit) usable to navigate the flexible elongate member away from the obstacle and on course to the treatment site.
A medical system may include: a medical device including an elongate shaft configured to access a treatment site within a patient and a handle coupled to a proximal end of the elongate shaft; a laser device including an elongate tubular member configured for insertion through a working lumen of the medical device, the elongate tubular member including a cooling channel and a laser fiber extending distally within the cooling channel; and a fluid management system including an inflow pump configured to pump fluid from a first fluid supply source through the elongate shaft to the treatment site, a cooling pump configured to pump fluid from a second fluid supply source through the cooling channel, and a controller configured to control the inflow pump and the cooling pump.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a collapsed configuration and an expanded configuration, an occlusive member disposed along at least a portion of the expandable framework and a sealing member disposed along the occlusive member.
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to devices, systems, and methods for securing tissue, such as a tissue defect or wound resulting from an endoscopic procedure, e.g., an endoscopic mucosal resection or submucosal dissection procedure. In one example, a device for securing tissue may include a loop portion configured to be disposed about a distal end of a delivery device in a delivery configuration and configured to be secured about the tissue in a deployed configuration. A locking member may be disposed on the loop portion. A tether portion having a proximal end extendable proximally within the delivery device and a distal portion extending from the loop portion slidably through the locking member.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
In an embodiment, a method for detecting leaks in a shaft of a cryoablation system includes placing a vacuum pump in fluid communication with a return tube and a supply tube; pulling a vacuum within the supply tube and the return tube; after pulling the vacuum for a predetermined amount of time, measuring a vacuum pressure within the supply tube and the return tube; and analysis of the vacuum pressure to assist with identifying leaks in the system.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
In an embodiment, a cryoablation shaft is included having a working fluid circuit; a vacuum circuit; an insulated portion, wherein the vacuum circuit runs through the insulated portion; and an expansion chamber; a supply tube having a distal outlet in the expansion chamber, wherein fluid from the working fluid circuit travels distally down the cryoablation shaft through supply tube and expands in the expansion chamber; and a guidewire lumen including a metallic tube and a polymer sleeve configured to surround at least a portion of the metallic tube.
A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
75.
BOTTLEBRUSH AND MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS
A reactive bottlebrush polymer for medical applications is described that comprises a polymer backbone and a plurality of polymer side chains linked to the polymer backbone, at least a portion of the side chains each comprising a hydrophilic polymer segment covalently linked to the polymer backbone and a reactive moiety covalently linked to the hydrophilic polymer segment at an end of the side chain opposite the polymer backbone. Also described for medical applications is a reactive multi-arm polymer that comprises three or more polymer arms that each comprise a hydrophilic polymer segment containing one or more types of polar aprotic vinyl monomer residues and a reactive moiety covalently linked to the hydrophilic polymer segment. A reactive polysaccharide for medical applications is further described that comprises a polysaccharide backbone that comprises free carboxyl groups and cyclic imide ester groups covalently attached along a length of the polysaccharide backbone.
C08L 101/14 - Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
According to an aspect, an implant, includes an inflatable member; a pump assembly, the pump assembly being configured to facilitate a transfer of fluid to and from the inflatable member; a tubular member extending from the pump assembly; a base member coupled to the pump assembly; and a coupling member configured to be disposed such that a portion of the tubular member is disposed between the base member and the coupling member to facilitate a coupling of the tubular member to the pump assembly.
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
77.
DEVICES, SYSTEMS, AND METHODS FOR PREVENTING ARCING BETWEEN ELECTRODES FOR MEDICAL PROCEDURES
An energy-delivering assembly probes formed from an elongated energy-delivering member have one or more electrodes defined along an energy-delivering region of the energy-delivering member. An electrode-defining insulation member is provided over the energy-delivering member to define and space apart at least a first electrode from a second electrode. One or more of the electrodes and/or insulation members are configured and/or have characteristics or properties which reduce/minimize/eliminate arcing between/across electrodes of the energy-delivering assembly.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A medical device may include an implant having a plurality of openings, a tube having a lumen extending therethrough, a body extending from a distal portion of the tube to a proximal portion of the implant, such that the plurality of openings are in fluid communication with the lumen, and a grasping portion configured to be grasped by a second medical device.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
79.
MEDICAL SYSTEMS, DEVICES, AND RELATED METHODS FOR WOUND THERAPY
A medical system that includes a handle, a shaft extending distally from the handle, and a cap assembly coupled to the distal end of the shaft. The shaft includes one or more channels extending between the handle and a distal end of the shaft, and the cap assembly includes an opening that is configured to expose the one or more channels at the distal end of the shaft. The cap assembly includes a chamber that extends distally from the opening. The medical system includes a porous body movably disposed within the chamber. The porous body is configured to transition from a compressed configuration when disposed inside the chamber to an expanded configuration upon extending outwardly from the chamber.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
An expandable dilator for use with an expandable sheath includes a shaft having a tapered distal tip, a body, a proximal end, and a lumen extending longitudinally from the distal tip to the proximal end. The expandable dilator includes an expansion mechanism extending radially outward from the outer surface of the shaft. When the expandable dilator is withdrawn proximally into the expandable sheath, the expansion mechanism engages the distal end of the sheath and expands the sheath as the expansion mechanism moves proximally through the sheath.
This disclosure relates to the field of luminal surgery. Specifically, the present disclosure relates to medical devices that expand within a body lumen for accessing a target tissue. In an aspect, an expandable device for a body lumen may include a filament comprising a proximal end, a distal end, and a length. The device may include a plurality of segments. Each segment may comprise a middle portion comprising a longitudinal axis extending axially therethrough, a projection portion extending from an end of the middle portion along the longitudinal axis, and a receptive portion extending from an opposing end of the middle portion away from the longitudinal axis, the receptive portion configured to receive the projection portion of an adjacent one of the plurality of segments. An aperture may be disposed through the projection portion, the middle portion, and the receptive portion.
Various embodiments described hereby may separate one or more functionalities/components provided via the tower in order to alleviate the physical barrier created by the umbilicus and reduce the need of the umbilicus to connect to the tower. For example, the liquid source may be worn by the user (e.g., physician) or the liquid source may modularly attach to the endoscope, such as to the handle of the endoscope. Accordingly, several embodiments described hereby may improve user experience such as by giving the user greater freedom of movement without sacrificing functionality. Some embodiments provide a source and means of using water without requiring the umbilicus to physically attach to the tower, improving range and ease of motion for a user by removing the need to navigate about a water connector.
A system for treating tissue includes a clip assembly including a pair of clip arms. Proximal ends of the clip arms are slidably received within a channel of a capsule to be moved between a tissue receiving configuration and a tissue clipping configuration. The system also includes a catheter assembly including a control member extending therethrough. The control member includes a distal end connected to the clip arms to move the clip assembly between the receiving and clipping configurations. The system further includes a coupler releasably coupled to a proximal end of the capsule and configured to be coupled to the distal end of the catheter assembly. The coupler fractures when a proximal force exerted on the coupler via the control member exceeds a first predetermined threshold value to disengage the capsule and deploy the clip assembly.
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A medical insertion device includes an elongated shaft extending from a proximal end to a distal end and having flexibility sufficient for insertion through a working channel of an endoscope along a tortuous path. The elongated shaft includes a coil extending from the proximal end to the distal end and having a channel extending longitudinally therethrough and a braided portion extending around a portion of the coil, the braided portion including a plurality of lines wound together such that first and second ones of the lines intersect to enclose a predetermined angle therebetween, the angle being between 25 and 55 degrees.
A61B 17/10 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for applying or removing wound clamps; Wound clamp magazines
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A61B 17/29 - Forceps for use in minimally invasive surgery
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
An endoscopic tissue grasper device includes a flexible tubular member, a flexible shaft extending through the tubular member, a proximal handle for moving the shaft and tubular member relative to each other, and a distal helical coil having a sharpened end for engaging tissue. The tissue grasper is advanced through a working channel of an endoscope, engaged relative to tissue, and retracted to pull tissue into a path of a movable needle coupled at a distal end of the endoscope so that the needle can be passed through the tissue. The needle is preferably provided with a suture so that as the needle is passed through the tissue a stitch is formed.
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A61B 17/04 - Surgical instruments, devices or methods, e.g. tourniquets for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith for suturing wounds; Holders or packages for needles or suture materials
A61B 17/06 - Needles; Holders or packages for needles or suture materials
An implantable medical device system (20) is disclosed. The implantable medical device (30) includes a housing forming an internal compartment. Electronic components are disposed within the internal compartment. An interface system (42) receives power signals, wireless electrical communication signals, or both. An elongated tether (44) having a conductive lead mechanically couples the housing to the interface system and allows the housing and interface system to be implanted at spaced-apart locations within the patient (22). The conductive lead electrically couples the interface system to the electronic components.
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
An implantable medical device (30) is disclosed. The implantable medical device includes a housing (32) forming an internal compartment (34). The housing includes a frame (36) disposed within the internal compartment forming a first partition (38) and a second partition (40) within the internal compartment. The first partition is hermetically sealed from the second partition. At least one electronic component (44) and a power source are disposed within the first partition. The medical device includes a fluidics circuit (46) including a manifold operably coupled to at least one fluidics component. The fluidics circuit is operably coupled to the at least one electronic component across the frame.
An energy-delivering assembly probes formed from an elongated energy-delivering member have one or more electrodes defined along an energy-delivering region of the energy-delivering member. An electrode-defining insulation member is provided over the energy-delivering member to define and space apart at least a first electrode from a second electrode. One or more of the electrodes and/or insulation members are configured and/or have characteristics or properties which reduce / minimize / eliminate arcing between / across electrodes of the energy-delivering assembly.
A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
89.
MEDICAL SYSTEMS, DEVICES, AND RELATED METHODS FOR WOUND THERAPY
A medical device includes a wire or tube, and a porous body coupled a distal portion of the wire or tube. The wire or tube is configured to be transitioned from a first configuration to a second configuration. In the first configuration, the wire or tube is in a flat or straight configuration. In the second configuration, the wire or tube is expanded to a curved or helical shape.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61L 29/14 - Materials characterised by their function or physical properties
90.
MEDICAL SYSTEMS, DEVICES, AND RELATED METHODS FOR WOUND THERAPY
A medical system that includes a handle, a shaft extending distally from the handle, the shaft including one or more channels extending between the handle and a distal end of the shaft, and a cap assembly coupled to the distal end of the shaft. At least one of the one or more channels includes a working channel. The cap assembly includes an opening that is positioned in alignment with at least one of the one or more channels at the distal end of the shaft. The medical system includes a chamber that extends distally from the opening and a porous body movably disposed within the chamber. The chamber is positioned in alignment with the working channel, and the porous body is configured to transition from a compressed configuration when disposed inside the chamber to an expanded configuration upon extending outwardly from the chamber.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61F 13/05 - specially adapted for use with sub-pressure or over-pressure therapy, wound drainage or wound irrigation, e.g. for use with negative-pressure wound therapy [NPWT]
An expandable dilator for use with an expandable sheath includes a shaft having a tapered distal tip, a body, a proximal end, and a lumen extending longitudinally from the distal tip to the proximal end. The expandable dilator includes an expansion mechanism extending radially outward from the outer surface of the shaft. When the expandable dilator is withdrawn proximally into the expandable sheath, the expansion mechanism engages the distal end of the sheath and expands the sheath as the expansion mechanism moves proximally through the sheath.
An implantable fluid operated inflatable device may include a fluid reservoir configured to hold fluid, an inflatable member, and fluidics architecture that provides for transfer of fluid between the fluid reservoir and the inflatable member. The fluid reservoir, the inflatable member, and the fluidics architecture may be included in a single unit, or a single housing, thus providing for a relatively compact implantable fluid operated inflatable device. The relatively simple, compact device provides for simplified insertion into the patient, and for simplified operation by the user.
An implantable medical device is disclosed. The implantable medical device includes a housing forming an internal compartment. Electronic components are disposed within the internal compartment. An interface system receives power signals, wireless electrical communication signals, or both. An elongated tether having a conductive lead mechanically couples the housing to the interface system and allows the housing and interface system to be implanted at spaced-apart locations within the patient. The conductive lead electrically couples the interface system to the electronic components.
A61F 2/00 - Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
An implantable medical device is disclosed. The implantable medical device includes a housing forming an internal compartment. The housing includes a frame disposed within the internal compartment forming a first partition and a second partition within the internal compartment. The first partition is hermetically sealed from the second partition. At least one electronic component and a power source are disposed within the first partition. The medical device includes a fluidics circuit including a manifold operably coupled to at least one fluidics component. The fluidics circuit is operably coupled to the at least one electronic component across the frame.
A medical device includes a wire or tube, and a porous body coupled a distal portion of the wire or tube. The wire or tube is configured to be transitioned from a first configuration to a second configuration. In the first configuration, the wire or tube is in a flat or straight configuration. In the second configuration, the wire or tube is expanded to a curved or helical shape.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A medical device including a distal body coupled to a distal end of a vacuum tube. The distal body may be in fluid communication with a lumen of the vacuum tube. The distal body may include a core having a plurality of openings and one or more layers surrounding the core.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A medical system that includes a handle, a shaft extending distally from the handle, the shaft including one or more channels extending between the handle and a distal end of the shaft, and a cap assembly coupled to the distal end of the shaft. At least one of the one or more channels includes a working channel. The cap assembly includes an opening that is positioned in alignment with at least one of the one or more channels at the distal end of the shaft. The medical system includes a chamber that extends distally from the opening and a porous body movably disposed within the chamber. The chamber is positioned in alignment with the working channel, and the porous body is configured to transition from a compressed configuration when disposed inside the chamber to an expanded configuration upon extending outwardly from the chamber.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
An example medical device is disclosed. The example medical device includes a tissue clipping device including a bushing having a distal end, a proximal end, and a lumen extending therethrough. A clip including at least a first arm and a second arm is configured to be coupled to the distal end of the bushing, wherein one of the first arm and the second arm includes a tissue grasping member. A control wire having a proximal end and a distal end, is configured to extend through the lumen of the bushing, and a helical member is configured to be coupled to the distal end of the control wire. The control wire is configured to advance the helical member in a distal direction along a longitudinal axis of the tissue clipping device, and retract the helical member in a proximal direction along the longitudinal axis of the tissue clipping device.
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
An example medical device is disclosed. The example medical device includes a shaft having a proximal end region, a distal end region and an outer surface. The medical device also includes a hemostasis clip coupled to the outer surface of the distal end region of the shaft, wherein the hemostasis clip is configured to shift between an open position and a closed position. Further, the medical device includes a tension member coupled to the hemostasis clip, wherein actuation of the tension member shifts the hemostasis clip between the open position and the closed position.
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A clipping system includes a clip having a pair of clip arms, proximal ends of the clip arms slidably received within a channel of a capsule to be moved between an open configuration and a closed configuration. A proximal end of the capsule including connecting tabs extending proximally therefrom. An applicator includes an elongated flexible member and a control member extending therethrough. The control member includes a distal end connected to the clip arms to move the clip assembly between the open and closed configurations. A distal end of the elongated flexible member includes a bushing including a first ramped surface, along which the connecting tabs slide along to engage a corresponding engaging feature of the bushing, and a second ramped surface proximal of the first ramped surface, the connecting tabs slidable along the second ramped surface to plastically deform toward a deployed configuration.
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
