Abstract

The present invention relates to an amylosome capable of saccharifying starch, and a method for treating waste food by using same. The amylosome capable of saccharifying starch, according to the present invention, can directly saccharify starch at a medium temperature in merely a single step, and can effectively decompose waste food contaminated with mold since, in addition to starch-degrading enzymes, mold-degrading enzymes are additionally introduced.

IPC Classes  ?

• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 14/33 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Clostridium (G)
• C12N 9/26 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on alpha-1, 4-glucosidic bonds, e.g. hyaluronidase, invertase, amylase
• C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
• B09B 3/60 - Biochemical treatment, e.g. by using enzymes
• B09B 101/70 - Kitchen refuseFood waste

Abstract

A composite according to an embodiment of the present invention is characterized by including a defect-induced carbon body and a metal oxide coupled to the carbon body. The composite according to an embodiment of the present invention induces defects in the carbon body, thereby improving interfacial properties between the carbon body and the metal oxide, and has an increased contact area, thereby improving electrochemical properties of the composite.

IPC Classes  ?

• H01G 11/24 - Electrodes characterised by structural features of the materials making up or comprised in the electrodes, e.g. form, surface area or porosityElectrodes characterised by the structural features of powders or particles used therefor
• H01G 11/26 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features
• H01G 11/32 - Carbon-based
• H01G 11/46 - Metal oxides
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes

Abstract

Disclosed are an apparatus, a method, and a system for displaying a mixed reality-based ultrasound image. The method for displaying a mixed reality-based ultrasound image, according to an embodiment of the present invention, may comprise the steps of: obtaining an ultrasound image captured by an ultrasound device and positioning information about a probe of the ultrasound device; generating, on the basis of color information about the ultrasound image, a composite image in which transparencies of a target region and a background region included in the ultrasound image are adjusted to be distinguished from each other; and outputting the composite image according to an output position determined by using the positioning information.

IPC Classes  ?

• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

Abstract

The present invention relates to a composition for preventing or treating Alzheimer's disease, comprising a phospholipase C (PLC) activator as an active ingredient. A composition comprising the PLC activator of the present invention as an active ingredient restores the S-eCB mobilization suppressed by AβO, recovers the synaptic plasticity impaired by AβO, and not only recovers PLCβ1 protein levels to normal levels in AβO-treated mouse hippocampal slices and 5XFAD mouse hippocampal slices in the chronic stage of AD, but also recovers contextual fear memory impairment in AD mice, and thus is expected to be usefully used for preventing or treating Alzheimer's disease.

IPC Classes  ?

• A61K 31/18 - Sulfonamides
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The present invention relates to a separator membrane having a hierarchical structure, a production method therefor and a xylene separation method using same, and to: a separator membrane having a hierarchical structure comprising mesopores, the separator membrane having mesopores introduced inside a microporous zeolite separator membrane, thereby being thin, having less defects and exhibiting high xylene permeation and separation performance; a production method therefor; and a xylene separation method using same.

IPC Classes  ?

• B01D 71/02 - Inorganic material
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranesMembrane supports

Abstract

There is provided a tag device including a first sensor, a second sensor, a pre-processor and a neural network processor. The pre-processor generates first position data of the tag device based on time information sensed by at least one of a third sensor included in each of the one or more anchor devices and the first sensor of the tag device, generates second position data based on first speed data of the tag device sensed by the second sensor and the first position data, and generates an image based on a path of movement of the tag device based on the second position data in an operation period, and the neural network processor classifies the image into one of a plurality of movements by using a trained neural network model.

IPC Classes  ?

• G01C 21/14 - NavigationNavigational instruments not provided for in groups by using measurement of speed or acceleration executed aboard the object being navigatedDead reckoning by recording the course traversed by the object
• G01P 13/00 - Indicating or recording presence or absence of movementIndicating or recording of direction of movement
• G06T 7/277 - Analysis of motion involving stochastic approaches, e.g. using Kalman filters

Abstract

The present invention relates to a device for maintaining vertebral body spacing and protecting the spinal cord. The device for maintaining vertebral body spacing and protecting the spinal cord, according to an embodiment of the present invention, comprises: a first body extending in the longitudinal direction; and a second body extending in the longitudinal direction, wherein the first body and the second body mutually approach to be coupled to each other, and are provided to form an internal space extending in the longitudinal direction therebetween and accommodate the spinal cord in the internal space, the first body includes: a first sleeve extending in the longitudinal direction; a first support portion extending forward from opposite sides in the longitudinal direction of the first sleeve; and a first accommodation portion extending in the longitudinal direction from the rear side of the first sleeve, the second body includes: a second sleeve extending in the longitudinal direction; a second support portion extending forward from opposite sides in the longitudinal direction of the second sleeve; and a second accommodation portion extending in the longitudinal direction from the rear side of the second sleeve, and the first support portion and the second support portion may be inserted between separated vertebral bodies.

IPC Classes  ?

• A61B 17/70 - Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant

Abstract

Disclosed is a method for manufacturing a photovoltaic module including forming a solar cell assembly by connecting a plurality of solar cells in an alignment direction in series, forming a plurality of solar cell units by cutting the solar cell assembly along a cutting line in a direction being different from the alignment direction, and disposing the plurality of solar cell units in an encapsulation member such that angles defined by a height direction of the encapsulation member and upper surfaces of the solar cell units are 30 degrees to 90 degrees.

IPC Classes  ?

• H01L 31/05 - Electrical interconnection means between PV cells inside the PV module, e.g. series connection of PV cells
• H01L 31/048 - Encapsulation of modules
• H01L 31/18 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof

Abstract

Provided are a base editor, specifically, a base editor in the form of a ribonucleoprotein (RNP) complex, and uses in gene correction in vivo using the same. When using the base editor in the form of an RNP complex of the present disclosure, target genes can be effectively corrected by reducing off-target effects.

IPC Classes  ?

• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• C12N 9/22 - Ribonucleases
• C12N 9/78 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• C12N 15/90 - Stable introduction of foreign DNA into chromosome

Abstract

According to various embodiments, a server providing an advertisement contract mediation platform may: acquire product feature information on the basis of at least one piece of content on a specific product acquired from a first external device; acquire a celebrity image of a specific celebrity among one or more celebrity images acquired from a second external device; acquire awareness information about the specific celebrity; acquire an advertisement image on the basis of the celebrity image, the product feature information, and the awareness information, the advertise image being an image in which the product feature information and the awareness information are overlapped with at least a partial area of the celebrity image; in response to the advertisement information including the advertisement image being transmitted to the second external device, acquire first result data indicating whether an advertisement contract is approved; and transmit contract information indicating the execution of the advertisement contract and acquired on the basis of the first result data to at least one of the first external device or the second external device so as to be output. Various other embodiments understood through the specification are possible.

IPC Classes  ?

• G06Q 30/02 - MarketingPrice estimation or determinationFundraising
• G06Q 30/06 - Buying, selling or leasing transactions
• G06N 20/00 - Machine learning

Abstract

An autofluorescence imaging device, according to one embodiment of the present disclosure, comprises: a light source for illuminating an examined eye through a preset optical path; an image sensor for imaging the examined eye of which at least a portion is emitting autofluorescence by the illumination from the light source; and a filter disposed between the image sensor and the examined eye, wherein the filter may comprise a plurality of portions each having mutually different light transmittances.

IPC Classes  ?

• A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes

Abstract

The present invention relates to an ultrasonic transducer position setting device, an ultrasonic transducer position setting program, and a method for implementing ultrasonic transducer position setting artificial intelligence. The ultrasonic transducer position setting device includes: an input/output unit for allowing a user to input data, and outputting the data in a form that is recognizable by the user; a memory for storing an ultrasonic transducer position setting program; and a control unit for executing the ultrasonic transducer position setting program to derive result data according to the data input through the input/output unit, wherein, when a focal point position of ultrasound, which is set to a region where a brain is positioned inside a skull in a living body, is input, the control unit outputs position data of an ultrasonic transducer, which allows the ultrasound to be applied to the input focal point position of the ultrasound.

IPC Classes  ?

• A61N 7/00 - Ultrasound therapy
• G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices

Abstract

The present invention provides a composition for preventing or treating muscular dystrophy, the composition comprising Zaltoprofen as an active ingredient. The composition according to the present invention increases the expression of utrophin, reduces the expression of myostatin, MAFbx, and MuRF1, and can inhibit muscle loss, increase muscle, and improve muscle function by inducing muscle differentiation and increasing the diameter of myotubes. Thus, the composition is expected to be used in various ways as medicines, quasi-medicines, fragrance materials, functional biomaterials, and functional food materials for alleviating, preventing, or treating muscular dystrophy.

IPC Classes  ?

• A61K 31/38 - Heterocyclic compounds having sulfur as a ring hetero atom
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system

Abstract

The present invention relates to: a catalyst for depolymerization of a polycarbonate-based resin, comprising a compound represented by chemical formula 1; a method for preparing same; a method for decomposing a polycarbonate-based resin using same; and a method for recovering the catalyst for depolymerization of a polycarbonate-based resin.

IPC Classes  ?

• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
• B01J 31/04 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing carboxylic acids or their salts
• B01J 37/04 - Mixing
• B01J 38/48 - Liquid treating or treating in liquid phase, e.g. dissolved or suspended
• C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
• C07C 37/055 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by oxygen, e.g. ether group
• C07C 37/70 - SeparationPurificationStabilisationUse of additives by physical treatment
• C07C 39/16 - Bis(hydroxy phenyl)alkanesTris(hydroxy phenyl)alkanes

Abstract

A method for detecting an anomaly, which is performed by a computing device including one or more processors according to some embodiments of the present disclosure may include: collecting a CAN message generated in a controller area network (CAN); generating first traffic time interval data and first payload data based on the CAN message; obtaining a first latent vector generated by inputting the first traffic time interval data into a first neural network model; obtaining a second latent vector generated by inputting the first payload data into a second neural network model; generating merged data in which the first latent vector and the second latent vector are merged; and determining whether the CAN message is anomalous by inputting the merged data into a third neural network model.

IPC Classes  ?

• H04L 9/40 - Network security protocols
• G06N 3/0495 - Quantised networksSparse networksCompressed networks

Abstract

Disclosed is a decision feedback equalizer, which includes a summator that receives a gray code-based PAM-4 signal, a first bit signal, and a second bit signal, and outputs an input voltage obtained by adding a preset coefficient to a voltage level of the PAM-4 signal in response to the first bit signal and the second bit signal, and a decoder that receives the input voltage and first to third reference voltages of the PAM-4 signal and outputs the first bit signal and the second bit signal, and the decoder includes a first comparator that outputs the first bit signal by comparing a magnitude of the input voltage with a magnitude of the first reference voltage, and a second comparator that outputs the second bit signal by comparing charge-discharge intensities of the input voltage and the second and third reference voltages.

IPC Classes  ?

• H04L 25/03 - Shaping networks in transmitter or receiver, e.g. adaptive shaping networks

Abstract

43233).

IPC Classes  ?

• H03B 19/14 - Generation of oscillations by non-regenerative frequency multiplication or division of a signal from a separate source by means of discharge device or semiconductor device with more than two electrodes by means of a semiconductor device
• H03B 19/18 - Generation of oscillations by non-regenerative frequency multiplication or division of a signal from a separate source using uncontrolled rectifying devices, e.g. rectifying diodes or Schottky diodes and elements comprising distributed inductance and capacitance
• H01P 5/02 - Coupling devices of the waveguide type with invariable factor of coupling

Abstract

The present invention relates to a composition and a kit for diagnosing autism disorder. The composition, the kit, and a method for providing information according to the present invention can conveniently and effectively diagnose autism disorder in a small amount of blood by using multiple biomarkers in which proteins and metabolites have been combined in order to diagnose autism disorder.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

The present invention relates to a cerebral blood flow measuring device comprising: a flexible base configured to be transformed correspondingly to the shape of a head in close contact therewith; a plurality of light irradiation units provided on an installation surface, facing the head, of the flexible base; a plurality of light detection units provided on the installation surface; and an expansion unit configured to transform the flexible base. The cerebral blood flow measuring device using near-infrared spectroscopy according to the present invention can improve measurement accuracy by actively adjusting the pressure of the flexible base to thus bring the light irradiation units and the light detection units into close contact with each other according to the shape and size of the head.

IPC Classes  ?

• A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

Disclosed is a device and method of training a deep learning model capable of using multi-level and multi-length latent vectors. The method of training the deep learning model is performed by a computing device including at least a processor and includes generating a basic model; and training the basic model, and the basic model includes a plurality of layer blocks each including at least one layer, and the layer blocks include first layer blocks configured to receive input data or output of a previous layer block to compress or encode data, or to output a latent vector corresponding to the input data and second layer blocks configured to receive the latent vector and the output of the previous layer block to restore or decode the data, or to derive inference results corresponding to the input data.

IPC Classes  ?

• G06N 3/08 - Learning methods
• G06N 3/0455 - Auto-encoder networksEncoder-decoder networks

Abstract

The present disclosure relates to a method of determining satellite orbital positions and routing for a Low Earth Orbit (LEO) satellite network, and the method calculates a communication throughput in each of a link between the transmitting base station and a satellite deployed on the first orbit, a link between satellites deployed on the first and second orbits, and a link between a satellite deployed on the second orbit and the receiving base station, and calculating a communication throughput in an entire link between the transmitting base station and the receiving base station on the basis of the communication throughput in each link, determines satellite orbital position variables and routing variables for maximizing the communication throughput in the entire link, and determines deployment of satellites on the first and second orbits on the basis of the satellite orbit position variables and routing variables.

IPC Classes  ?

• H04B 7/185 - Space-based or airborne stations

Abstract

The method for predicting Alzheimer's disease-related biomarkers according to the present disclosure involves a method executed by one or more processors of a computing device. The method comprises collecting medical images of a subject, preprocessing the collected medical images to generate training data, training a biomarker prediction model using the generated training data and the subject's demographic and clinical information, where the training includes assigning weights to the training data, and predicting Alzheimer's disease-related biomarkers for a patient using the trained biomarker prediction model.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Abstract

A resource block scheduling method and an electronic device performing the method are disclosed. An electronic device according to various embodiments may comprise: at least one processor, comprising processing circuitry, and a memory electrically connected to at least one processor and storing instructions executable by the processor, wherein at least one processor, individually and/or collectively, is configured to execute the instructions and to: A resource block scheduling method and an electronic device performing the method are disclosed. An electronic device according to various embodiments may comprise: at least one processor, comprising processing circuitry, and a memory electrically connected to at least one processor and storing instructions executable by the processor, wherein at least one processor, individually and/or collectively, is configured to execute the instructions and to: based on channel quality information indexes (CQIs) relating to a plurality of terminals, acquire achievable rates based on resource blocks being allocated to the plurality of terminals; and input the achievable rates to a trained neural network model to output a schedule for allocation of the resource blocks to the plurality of terminals, and the neural network model is configured to be trained to collect the training CQIs relating to the plurality of terminals, acquire, based on the training CQIs, training achievable rates based on the resource blocks being allocated to the plurality of terminals, and output the schedule, in which the sum of the rates for the plurality of terminals is maximized and fairness indexes for the plurality of terminals satisfy a configured fairness condition, using the input training achievable rates.

IPC Classes  ?

• H04W 72/121 - Wireless traffic scheduling for groups of terminals or users
• H04W 72/542 - Allocation or scheduling criteria for wireless resources based on quality criteria using measured or perceived quality

Abstract

The present invention relates to a method for efficiently preparing rucaparib for a PET image. More specifically, the present invention relates to an improved preparation method for synthesizing [18F]-rucaparib in excellent yield by means of a pathway for synthesizing a pinacol boronate derivative, which is a key intermediate, by using, as a starting material, a 2-iodoaniline derivative prepared by a novel synthesis method.

IPC Classes  ?

• C07D 487/04 - Ortho-condensed systems
• C07B 59/00 - Introduction of isotopes of elements into organic compounds
• C07D 209/18 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
• A61K 51/04 - Organic compounds

Abstract

The present invention relates to a method for efficiently preparing 2-amino-4-fluoro-6- methoxycarbonylcinnamonitrile. More specifically, the present invention relates to an improved preparation method for synthesizing 2-amino-4-fluoro-6-methoxycarbonylcinnamonitrile, which is a key intermediate in preparing rucaparib with excellent yield through a novel synthesis route using, as a starting material, alkyl 5-fluoro-2-methyl-3-nitrobenzoate rather than a conventional 2-iodoaniline derivative.

IPC Classes  ?

• C07C 253/30 - Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
• C07C 255/42 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
• C07C 255/64 - Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to oxygen atoms
• C07C 255/41 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups

Abstract

Disclosed is an electricity generation device. The present invention provides an electricity generation device, including: a first electrolyte, selectively permeable membrane, and second electrolyte in a chamber thereof, wherein each of the first electrolyte and the second electrolyte includes at least two types of ions, and at least three types of ions are included in the first electrolyte and the second electrolyte, the selectively permeable membrane selectively permeates at least one type of ions among the at least three types of ions to cause Donnan effect between the first electrolyte and the second electrolyte.

IPC Classes  ?

• H01M 8/22 - Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elementsFuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen
• H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells

Abstract

Disclosed is a privacy-preserving electrocardiogram (ECG) data collecting method for arrhythmia classification. The privacy-preserving ECG data collecting method is performed by a computing device including at least a processor and includes training a feature extraction model, a personal identification model, and an arrhythmia classification model using learning data that includes ECG data with a predetermined length; and training a noise model, and the feature extraction model receives the ECG data as input and outputs ECG features, the personal identification model receives the ECG features as input and identifies an individual corresponding to the ECG features, the arrhythmia classification model receives the ECG features as input and classifies arrhythmia corresponding to the ECG features, and the noise model generates noise with the same length as that of the ECG features.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• A61B 5/349 - Detecting specific parameters of the electrocardiograph cycle
• G06N 3/045 - Combinations of networks
• G06N 3/084 - Backpropagation, e.g. using gradient descent

Abstract

Disclosed is a field programmable gate array device including a plurality of lookup tables each storing data. Each lookup table includes a cell array including cells connected to a plurality of word lines, a drive circuit connected to the cell array through the plurality of word lines, and a peripheral circuit connected to the cell array through a plurality of bit lines and source lines, and configured to control the drive circuit. The drive circuit drives a first word line among the word lines based on first input signals. The peripheral circuit performs a data write operation on a first cell connected to the first word line, based on a first command and a second input signal, and performs a data read operation on the first cell connected to the first word line, based on a second command and the second input signal.

IPC Classes  ?

• G06F 3/06 - Digital input from, or digital output to, record carriers
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• H03K 19/17728 - Reconfigurable logic blocks, e.g. lookup tables

Abstract

The present disclosure relates to a novel human antibody or an antigen-binding fragment thereof that recognizes the SMO (smoothened) protein as an antigen and binds specifically thereto. The antibody of the present disclosure binds specifically to the SMO protein, which is directly involved in major cancer progression processes such as proliferation, migration, invasion and metastasis of cancer cells, and blocks the progression those processes. Therefore, it can be usefully used as a therapeutic agent for various cancers such as colon cancer, etc., resistant cancer, metastatic cancer, or recurrent cancer.

IPC Classes  ?

• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 35/00 - Antineoplastic agents
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

Abstract

The present invention relates to a building drawing design device and method, the building drawing design method comprising the steps of: acquiring basic data for generating a building drawing; using a trained learning model to acquire a generation drawing corresponding to the basic data; and performing post-processing on the generation drawing so as to acquire a resulting drawing corresponding to the basic data, wherein the trained learning model can be acquired by the steps of: acquiring at least one reference drawing corresponding to at least one original drawing; removing some or all of the space of the at least one reference drawing so as to generate at least one input drawing corresponding to the at least one reference drawing; and training the learning model by using the at least one reference drawing and the at least one input drawing.

IPC Classes  ?

• G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
• G06F 30/13 - Architectural design, e.g. computer-aided architectural design [CAAD] related to design of buildings, bridges, landscapes, production plants or roads
• G06V 30/422 - Technical drawingsGeographical maps
• G06V 10/24 - Aligning, centring, orientation detection or correction of the image
• G06F 16/11 - File system administration, e.g. details of archiving or snapshots
• G06F 119/10 - Noise analysis or noise optimisation

Abstract

Disclosed is a device and method for lightweight container packet processing in an Internet of things (IoT) environment. A packet processing method is performed by a server that provides a container environment to an IoT device and includes receiving a packet from a container assigned to the IoT device; determining a packet processing path to process the packet; processing the packet according to the determined packet processing path; and transmitting the packet of which packet processing is completed to an external network.

IPC Classes  ?

• H04L 45/745 - Address table lookupAddress filtering

Abstract

The present invention relates to miRNA-4449, which is a biomarker that can be used to diagnose nonalcoholic steatohepatitis, and at least one miRNA selected from the group consisting of miRNA-15, miRNA-21, miRNA-29, miRNA-126, miRNA-151, miRNA-183, and miRNA-192. The prognosis of nonalcoholic steatohepatitis among nonalcoholic fatty liver diseases is poor unlike simple steatosis. According to the present invention, the level of the miRNA can be measured in the serum of a patient to provide an accurate diagnostic result of nonalcoholic steatohepatitis, thus making it possible to eliminate side effects caused by conventional invasive test methods, and enabling early diagnosis and appropriate treatment of steatohepatitis in a simple and economical manner.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

Disclosed is an implantable monitoring and treatment device. The implantable monitoring and treatment device comprises: a jacket unit which surrounds an organ in the body and is made of an elastic material so as to deform according to the expansion and contraction of the organ; and a biometric signal measurement unit which is provided in the jacket unit and measures biometric signals from the organ. The jacket unit includes: a first pad which has a prescribed area and is in close contact with one region of the organ; a second pad which has a prescribed area and is in close contact with another region of the organ; and at least one fastening string connecting the first pad and the second pad.

IPC Classes  ?

• A61B 5/251 - Means for maintaining electrode contact with the body
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/283 - Invasive
• A61B 5/296 - Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]

Abstract

Disclosed are a signal measurement device for measuring signals of a plurality of organoids, and a control method for controlling the signal measurement device. The signal measurement device may comprise: a well plate in which chambers accommodating organoids are disposed; a probe array including probes in which electrodes are disposed; a cover in which the probe array is disposed; a gap adjustment unit for adjusting a gap between the well plate and the probe array; and a control unit for controlling the gap adjustment unit to adjust the gap between the well plate and the probe array on the basis of changes in an electrical signal measured by the electrodes.

IPC Classes  ?

• G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
• G01N 33/483 - Physical analysis of biological material
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12N 5/079 - Neural cells
• G01N 27/327 - Biochemical electrodes
• G01B 7/16 - Measuring arrangements characterised by the use of electric or magnetic techniques for measuring the deformation in a solid, e.g. by resistance strain gauge

Abstract

A screening device for analyzing multiple organoids is disclosed. The screening device comprises: a microfluidic chip in which one or more microfluidic channels through which a drug flows are arranged; a well plate in which a plurality of chambers accommodating organoids are arranged; and a probe array in which probes inserted into the organoids so as to measure a signal in each organoid are arranged in an array form, wherein a first microfluidic channel among the one or more microfluidic channels is arranged to be adjacent to a first chamber array in which some of the chambers are arranged in an array form, and the drug flowing in the first microfluidic channel can be delivered to each organoid accommodated in the first chamber array through porous films having different porosities.

IPC Classes  ?

• G01N 33/483 - Physical analysis of biological material
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• C12N 5/079 - Neural cells

Abstract

Provided are Fc variants having improved half-life by binding to and unbinding from FcRn in a pH-dependent manner, which have improved capacity to selectively bind to Fcγ receptors. The human Fc domain variants have lower capacity to bind to immune-inhibiting receptor FcγRIIb and have higher capacity to bind to immune activating receptor FcγRIIIa (increased A/I ratio) than a wild-type human antibody Fc domain and conventional antibodies approved as antibody therapeutic agents, thereby having remarkably improved ADCC induction ability and having maximized half-life in blood in which excellent pH-selective FcRn binding and unbinding capacity is exhibited, and thus bind to numerous peptide drug therapeutics having a low half-life and retention time in the body to enable the peptide drug therapeutics to have an increased blood half-life and exhibit long-term drug efficacy, and can maximize the immune mechanism of therapeutic protein drugs to be effectively used as an improved antibody drug.

IPC Classes  ?

• C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment

Abstract

Disclosed herein are a method and a biomarker for predicting efficacy and prognosis of or resistance to an immunotherapy. The use of the biomarkers (TCTP, EGFR, AKT, MCL1, and/or CXCL10) of the present disclosure allows the prediction of resistance to or prognosis of a cancer immunotherapeutic agent and the selection of a therapy guaranteeing therapeutic benefit, thereby finding advantageous applications in treating cancers or tumors resistant to cancer immunotherapeutic agents.

IPC Classes  ?

• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The present invention relates to a chromene-benzimidazole derivative or a pharmaceutically acceptable salt thereof, and a composition containing the derivative as an active ingredient for preventing or treating cancer. The chromene-benzimidazole derivative of the present invention is activated in cancer cells to inhibit tubulin polymerization and suppress the C-terminal domain of Hsp90, thereby blocking the cell cycle of cancer cells, inducing apoptosis, and inhibiting the activity of oncoproteins, and thus can be used as a novel dual-target anticancer drug for preventing or treating cancer, preferably for preventing or treating triple-negative breast cancer.

IPC Classes  ?

• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
• A61P 35/00 - Antineoplastic agents

Abstract

A semiconductor device includes a capacitor including a first electrode, a second electrode, and a dielectric layer between the first electrode and the second electrode, where at least one of the first electrode and the second electrode includes a nanolaminate electrode, the nanolaminate electrode includes a plurality of first material layers and a plurality of second material layers, the plurality of first material layers and the plurality of second material layers being alternately arranged, the plurality of first material layers includes indium oxide (In2O3), the plurality of second material layers includes molybdenum oxide (MoOx), each of the plurality of first material layers has a thickness between about 2 angstroms to about 6 angstroms, and each of the plurality of second material layers includes a monolayer of molybdenum oxide.

IPC Classes  ?

• H01G 4/06 - Solid dielectrics

Abstract

Disclosed is a qubit system based on magnetic resonance, according to some embodiments of the present disclosure. The qubit system may comprise: a magnet having a space provided on the inside thereof; a qubit sample which is disposed in the space provided on the inside of the magnet and contains a material capable of quantum state transition; a gradient coil which is disposed on the outside of the qubit sample to correspond to the qubit sample on the inside of the magnet and generates a gradient magnetic field in the space on the inside of the magnet, which has the qubit sample contained therein; an RF transmitting coil part disposed between the qubit sample and the gradient coil on the inside of the magnet, to apply radio frequency (RF) pulses to the qubit sample and control a quantum state of the qubit sample; and an RF receiving coil disposed on the inside of the magnet to receive RF signals emitted from the qubit sample due to the applied RF pulses.

IPC Classes  ?

• G06N 10/40 - Physical realisations or architectures of quantum processors or components for manipulating qubits, e.g. qubit coupling or qubit control
• G06N 10/20 - Models of quantum computing, e.g. quantum circuits or universal quantum computers
• G06N 20/10 - Machine learning using kernel methods, e.g. support vector machines [SVM]
• B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic

Abstract

A method of reconstructing a downlink (DL) channel by a base station in a multiple-input-multiple-output (MIMO) communication system includes: estimating UL channel information on the basis of an uplink (UL) pilot signal received from a user equipment; extracting at least one key parameter among common parameters of the UL channel and the DL channel from the estimated UL channel information; estimating DL channel information using the UL channel information and the at least one key parameter; and reconstructing the DL channel by correcting an error between the estimated DL channel information and actual DL channel information.

IPC Classes  ?

• H04B 7/0413 - MIMO systems
• H04L 5/00 - Arrangements affording multiple use of the transmission path
• H04W 72/1273 - Mapping of traffic onto schedule, e.g. scheduled allocation or multiplexing of flows of downlink data flows
• H04W 72/21 - Control channels or signalling for resource management in the uplink direction of a wireless link, i.e. towards the network
• H04W 72/54 - Allocation or scheduling criteria for wireless resources based on quality criteria

Abstract

The present invention provides a composition for freezing control, a composition for freezing a cell, and a composition for freezing a food, which include a compound in which 2 to 5 amino acids, for example, 2, 3, 4, or 5 amino acids are connected to fluorenylmethyloxycarbony (Fmoc) through peptide bonding.

IPC Classes  ?

• A01N 1/02 - Preservation of living parts
• A23L 3/3526 - Organic compounds containing nitrogen
• A23L 3/3535 - Organic compounds containing sulfur

Abstract

An intestinal content delivery device for an intestinal fistula patient according to one embodiment of the present invention comprises: a nutrient delivery tube having a nutrient delivery passage inserted into an intestinal fistula of a user to deliver nutrients between an upper intestinal fistula and a lower intestinal fistula; and a nutrient supply tube coupled to one side of the nutrient delivery tube so as to communicate with the nutrient delivery passage. The nutrient delivery tube may comprise: an upper intestinal fistula insertion tube that is provided to be insertable into the upper intestinal fistula, has a first nutrient delivery passage, and has at least one first through-hole formed at one end thereof so that nutrients present in the upper intestinal fistula can flow therethough; and a lower intestinal fistula insertion tube that is provided to be insertable into the lower intestinal fistula, has a second nutrient delivery passage which communicates with the first nutrient delivery passage, and has at least one second through-hole formed at one end thereof so that nutrients delivered from the upper intestinal fistula through the first through-hole and the first nutrient delivery passage can be delivered to the lower intestinal fistula.

IPC Classes  ?

• A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts

Abstract

The present disclosure relates to a TIS-L targeting antisense oligonucleotide that inhibits the viral replication of SARS-COV-2 and antiviral use thereof. Since the TIS-L targeting antisense oligonucleotide according to the present disclosure has a simple structure, it is easy to mass produce, and as it exhibits antiviral efficacy of 90% or more even at low doses against the original strain and various modified strains of the virus, it can be advantageously utilized in the development of COVID-19 treatment.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61P 31/14 - Antivirals for RNA viruses

Abstract

Disclosed is a Light-Emitting Device-Thin Film Transistor (LED-TFT) integration structure, comprising a substrate comprising a light emitting area and a driving area; a metal reflective film formed on the substrate; a buffer layer formed on the metal reflective film; LED disposed in the light emitting area; a protective layer formed on the LED; a thin film transistor disposed in the driving area and configured to drive the LED; and an ohmic contact metal for electrically connecting a cathode of the LED with the metal reflective film, wherein the LED and the thin film transistor are integrally formed on the substrate.

IPC Classes  ?

• H01L 25/16 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices the devices being of types provided for in two or more different subclasses of , , , , or , e.g. forming hybrid circuits
• H01L 27/12 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being other than a semiconductor body, e.g. an insulating body
• H01L 33/12 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a stress relaxation structure, e.g. buffer layer
• H01L 33/46 - Reflective coating, e.g. dielectric Bragg reflector
• H01L 33/62 - Arrangements for conducting electric current to or from the semiconductor body, e.g. leadframe, wire-bond or solder balls

Abstract

The present invention relates to a POMC-specific antibody and use thereof, and use of Marchf6 for treating metabolic diseases. It has been found that the cytosolic accumulation of POMC, which is an appetite-regulating hormone precursor protein, induces ER stress and ferroptosis, and Marchf6 degrades POMC by directly binding thereto, causing the translocation of POMC into ER. Also, it has been confirmed that a produced POMC-specific antibody can specifically detect POMC accumulated in the cytosol of POMC neurons. Therefore, these can be used for the diagnosis and treatment of diseases associated with POMC accumulation or Marchf6 dysfunction. It has also been found that ER stress and ferroptosis caused by accumulation of POMC in the cytosol are regulated. In particular, it was confirmed in vivo that Marchf6 deficiency in POMC neurons causes metabolic disorders. Therefore, Marchf6 can be effectively used for the prevention or treatment of metabolic diseases, including obesity.

IPC Classes  ?

• C07K 14/665 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
• C07K 16/26 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones
• A61P 3/00 - Drugs for disorders of the metabolism
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A23L 33/17 - Amino acids, peptides or proteins
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

Disclosed is a method and apparatus for determining diagnosis result data by using a thermal image. A method for determining diagnosis result data may comprise the steps of: acquiring a first thermal image indicating a temperature change of skin, to which thermal stimulation has been applied, over time; acquiring a second thermal image indicating a temperature change of skin, to which cold stimulation has been applied, over time; extracting a temperature restoration feature of the skin from each of the first thermal image and the second thermal image; and determining diagnosis result data related to the skin on the basis of the temperature restoration feature extracted from the first thermal image and the temperature restoration feature extracted from the second thermal image.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G06T 7/00 - Image analysis
• G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
• G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
• G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment

Abstract

There is provided with a blockchain-based evidence data notarization system comprising a user terminal for transmitting the evidence data in accordance with a notarization request; a notary server for transmitting the generated hash value to the user terminal and a notary terminal, respectively; and a blockchain server for receiving a signature written in the hash value from the user terminal and the notary terminal, respectively and generating a smart contract block.

IPC Classes  ?

• G06Q 50/18 - Legal services
• H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols

Abstract

The present invention can provide a method for preparing a sulfide-based solid electrolyte in a short time using a solvothermal synthesis method. In addition, the present invention may provide a sulfide-based solid electrolyte prepared by the method. In addition, the present invention may provide an electrode for an all-solid-state battery including the sulfide-based solid electrolyte.

IPC Classes  ?

• H01M 10/0562 - Solid materials
• C01G 17/00 - Compounds of germanium
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

Abstract

The present invention relates to a zwitterionic polymer-based aqueous electrolyte having a high potential stability window through control of a hydration layer, and a manufacturing method thereof. According to one embodiment, a zwitterionic polymer-based aqueous electrolyte having a high potential stability window through control of a hydration layer may be provided, the zwitterionic polymer-based aqueous electrolyte including a polymer hydrogel having a three-dimensional network structure composed of: a zwitterionic polymer structure derived from an ionic polymer monomer and polymerized and crosslinked through a crosslinker and an initiator; and a hydration layer formed on the surface of the zwitterionic polymer structure.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/36 - Accumulators not provided for in groups
• C08F 230/02 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
• C08F 222/10 - Esters
• C08F 2/44 - Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
• C08K 3/105 - Compounds containing metals of Groups 1 to 3 or of Groups 11 to 13 of the Periodic Table

Abstract

The present invention relates to an electrolyte using a high-dielectric-constant zwitterionic material, and a preparation method therefor. According to an embodiment, the provided electrolyte using a high-dielectric-constant zwitterionic material, which is for a secondary battery using a metal anode material as an anode, comprises an electrolyte mixture composed of: an organic electrolyte including an organic solvent and a metal salt; and a zwitterionic compound having a weight average molecular weight that satisfies a range of 100-60,000 g/mol and having a zwitterion.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/134 - Electrodes based on metals, Si or alloys
• C08F 220/06 - Acrylic acidMethacrylic acidMetal salts or ammonium salts thereof
• C08F 222/10 - Esters
• C08F 2/44 - Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
• C08K 5/11 - EstersEther-esters of acyclic polycarboxylic acids

Abstract

The present disclosure provides a state estimation apparatus of estimating a current state of an object based on state information and observation information for dynamically replicating the object, the state estimation apparatus including an input unit that receives the observation information, and a current state estimation unit that generates current state estimation information through the observation information, wherein the current state estimation unit includes a prediction information generation unit that generates state prediction information through inputting past state estimation information obtained by delaying the current state estimation information by one time unit into a previously prepared state prediction model, and a prediction information correction unit that calculates a Kalman gain matrix associated with a degree of correction of the state prediction information through artificial neural network(s), and corrects the state prediction information through the observation information and the Kalman gain matrix to generate the current state estimation information.

IPC Classes  ?

• G01S 7/41 - Details of systems according to groups , , of systems according to group using analysis of echo signal for target characterisationTarget signatureTarget cross-section
• G01S 13/06 - Systems determining position data of a target

Abstract

Provided with a blockchain-based shared asset trading system for tokenizing and trading a shared asset comprising a plurality of sharer terminals, provided on a sharer side, for transmitting an original warranty containing the appraisal result of the shared asset and transmitting a warranty in which the sharer's signature has been entered to the original warranty; a blockchain network for receiving and storing the original warranty in a smart contract block, issuing a token based on the smart contract block and generating an electronic wallet in which the token is stored; and an electronic wallet management server for receiving the warranty in which the signature has been entered from the plurality of sharer terminals and transmitting a transaction including the warranty in which the signature has been entered to the original warranty.

IPC Classes  ?

• G06Q 20/38 - Payment protocolsDetails thereof
• G06Q 20/36 - Payment architectures, schemes or protocols characterised by the use of specific devices using electronic wallets or electronic money safes
• G06Q 30/012 - Providing warranty services
• G06Q 40/04 - Trading Exchange, e.g. stocks, commodities, derivatives or currency exchange
• G06Q 50/18 - Legal services

Abstract

Disclosed is a photovoltaic module including an encapsulation part, a plurality of solar cells disposed in the encapsulating part such that angles thereof with respect to a height direction of the encapsulation part is 30 degrees to 90 degrees, and impact absorption parts disposed between the plurality of solar cells in the encapsulation part.

IPC Classes  ?

• H01L 31/048 - Encapsulation of modules

Abstract

An embodiment of the present invention provides a processing-in-memory memory device comprising: a memory bank including a memory array for receiving a memory request from a memory controller, and a PIM engine for executing processing-in-memory according to the PIM instruction; and a processing-in-memory (PIM) control unit for controlling the processing-in-memory of the PIM engine by identifying a PIM instruction corresponding to the memory request, and storing addressing mode selection information for selecting one among an indirect address and a direct address according to the identified PIM instruction, wherein when the indirect address is used, the PIM control unit uses a register value of the processing-in-memory control unit as a base register value, reads an immediate value in the PIM instruction, a register value of the PIM engine, or an offset value of the memory bank, and generates an effective address for the processing-in-memory in an indirect addressing mode.

IPC Classes  ?

• G06F 9/30 - Arrangements for executing machine instructions, e.g. instruction decode

Abstract

Disclosed are a patterned optical stimulation device and method. The patterned optical stimulation device according to one aspect includes: an imaging unit which generates a skin tissue image; a diagnosis unit which detects a region of interest from the skin tissue image and diagnoses the detected region of interest; and an optical stimulation unit which forms patterned treatment light corresponding to the region of interest and irradiates the region of interest with the formed patterned treatment light.

IPC Classes  ?

• A61N 5/06 - Radiation therapy using light
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

The present invention provides a method and system for prediction of fall on the basis of EMG signals in a stroke patient. The method for prediction of fall on the basis of EMG signals in a stroke patient, according to one embodiment of the present invention, comprises the steps of: attaching an EMG sensor to a first part among lower limb muscles of the patient; measuring the EMG signals of the patient performing an exercise motion for collecting the EMG signals, by means of the EMG sensor attached to the first part; and determining a fall risk of the patient on the basis of the measured EMG signals.

IPC Classes  ?

• A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/397 - Analysis of electromyograms

Abstract

The present invention relates to: an in-situ truncation method for a nonessentials-inducing aptamer in an aptamer-protein conjugate; and a truncated aptamer that is prepared by the method and binds with high affinity to vaspin. Particularly, the present invention relates to: an in-situ aptamer truncation method comprising the steps of (1) mixing a target protein and an aptamer capable of binding to the target protein to form a conjugate of the aptamer and the target protein and (2) treating the conjugate of the aptamer and the target protein with exonuclease to remove nonessentials of the aptamer that do not bind to the target protein; a truncated aptamer that is prepared by the method and consists of an essential sequence that binds to the target protein; a kit for detecting a target protein, comprising the truncated aptamer; a method for preparing a truncated aptamer that binds to a vaspin protein, by the in-situ aptamer truncation method; and a truncated DNA aptamer that is prepared by the method and consists of an essential sequence that binds to a vaspin protein.

IPC Classes  ?

• C12N 9/22 - Ribonucleases
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C07K 14/81 - Protease inhibitors

Abstract

The present invention relates to a carbamate amine/amine-grafted metal-organic framework-based carbon dioxide adsorbent. According to the present invention, the provided carbon dioxide adsorbent maintains adsorption performance even in a flue gas environment containing high-concentration moisture and has improved reusability and stability.

IPC Classes  ?

• B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
• B01J 20/34 - Regenerating or reactivating
• C07C 269/04 - Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
• C07C 271/28 - Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
• B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography

Abstract

Disclosed is a method for scheduling a hydrogen and electric vehicle charging station, linked with renewable energy, by considering the HPS market. The scheduling method is performed by a computing device including a processor, and comprises the steps of: modeling the charging demand of the hydrogen and electric vehicle charging station; and scheduling the hydrogen and electric vehicle charging station through second-order conic programming (SOCP) repair optimization on the basis of the modeled charging demand, wherein the scheduling step includes the steps of: setting an objective function defined by an equation; and setting at least one constraint.

IPC Classes  ?

• G06Q 50/40 - Business processes related to the transportation industry
• G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
• G06Q 10/04 - Forecasting or optimisation specially adapted for administrative or management purposes, e.g. linear programming or "cutting stock problem"
• B60L 53/50 - Charging stations characterised by energy-storage or power-generation means
• B60L 58/40 - Methods or circuit arrangements for monitoring or controlling batteries or fuel cells, specially adapted for electric vehicles for controlling a combination of batteries and fuel cells
• H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers

Abstract

Disclosed is a magnetic random access memory (MRAM) device based on a ferromagnetic film with in-plane biaxial anisotropy. The MRAM device includes a substrate and a ferromagnetic layer formed on the substrate, and the ferromagnetic layer has biaxial anisotropy. In the present invention, information can store in a cell only with current pulses, which switches magnetization between easy-axes, because spin-orbit field component along easy axes changes with current direction. This may lead to an increase in the operating efficiency of the memory device.

IPC Classes  ?

• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• H01F 1/147 - Alloys characterised by their composition
• H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
• H10N 50/10 - Magnetoresistive devices
• H10N 50/85 - Materials of the active region

Abstract

The present invention relates to a composition for preventing or treating coronavirus infectious diseases, comprising a compound that binds to G4 structures of coronaviruses. Since the compound according to the present invention can bind to G4 structures of coronaviruses to stabilize the G4 structures, reduce the protein expression of coronaviruses, and effectively inhibit cell infection by viruses, the compound is expected to be used in the prevention or treatment of coronavirus infectious diseases.

IPC Classes  ?

• A61K 31/409 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
• A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 31/473 - QuinolinesIsoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
• A61K 31/4745 - QuinolinesIsoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
• A61K 31/5383 - 1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
• A61P 31/14 - Antivirals for RNA viruses

Abstract

The present disclosure relates to an anti-CD20 asymmetric antibody including a single-chain variable fragment (scFv) on one side and an antigen-binding fragment (Fab) on the other side. Compared to an antibody having a symmetric structure, the asymmetric antibody of the present disclosure effectively activates complements and exhibits significantly improved complement-dependent cytotoxicity (CDC), and thus can be advantageously used as an effective therapeutic agent or therapeutic adjuvant for treating cancer.

IPC Classes  ?

• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Abstract

The present invention relates to an extraction method for simultaneously performing biological material disruption and nucleic acid adsorption and, more specifically, to an extraction method for simultaneously performing biological material disruption and nucleic acid adsorption, which rapidly lyses the membrane of a biological material included in a biological sample, and immediately extracts and separates nucleic acids released from the biological material, thereby minimizing cleavage or destruction of the nucleic acids. According to the present invention, when a suitable chamber and blade are configured so that a biological material is disrupted by a rotating blade, the membrane of the biological material is mostly disrupted within several minutes by a high-speed rotating blade, whereby a material inside a cell can be easily extracted.

IPC Classes  ?

• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

Abstract

The present invention relates to an indazole-based compound having a synergistic effect on an antifungal agent and a use thereof and, more particularly, to: an antifungal adjuvant comprising, as an active ingredient, any one compound selected from the group consisting of formulae 1 to 16 or a pharmaceutically acceptable salt thereof; an antifungal combination preparation comprising the antifungal adjuvant and an Echinocandins antifungal agent as active ingredients; a pharmaceutical composition for preventing or treating fungal infections; and a method for inhibiting fungi in vitro, the method comprising a step for treating with a combination of the antifungal adjuvant of the present invention and an Echinocandins antifungal agent. When used in combination with an Echinocandins antifungal agent, the antifungal adjuvant provided in the present invention makes it possible to effectively inhibit the growth of fungi using only a small amount of the antifungal agent, and thereby induce an antibacterial synergistic effect of the antifungal agent and improve a bacteriostatic effect of the Echinocandins antifungal agent. Therefore, the antifungal adjuvant can be usefully used in the manufacture of an antibacterial composition for preventing fungal infection and a medicine for treating fungal infectious diseases.

IPC Classes  ?

• A61K 31/416 - 1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
• A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
• A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
• A61K 31/433 - Thiadiazoles
• A61K 31/422 - Oxazoles not condensed and containing further heterocyclic rings
• A61P 31/10 - Antimycotics

Abstract

The present invention relates to a novel ligand based on azine linkage, a metal-organic framework comprising same, and use thereof. The novel ligand based on azine linkage of the present invention can be usefully used as a material for preparing the metal-organic framework. In addition, the metal-organic framework comprising the novel ligand of the present invention has excellent gas adsorption ability, and thus can be usefully utilized as an adsorbent for gases including carbon dioxide.

IPC Classes  ?

• C07C 251/88 - Hydrazones having also the other nitrogen atom doubly-bound to a carbon atom, e.g. azines
• C07C 251/86 - Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
• C07D 487/04 - Ortho-condensed systems
• C07F 3/02 - Magnesium compounds
• B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
• B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography

Abstract

The present invention relates to a probe for measuring cathepsin K activity, a composition for measuring osteoclast activity comprising the probe, a composition for diagnosing bone diseases comprising the probe, a kit for measuring osteoclast activity comprising the composition, a kit for diagnosing bone diseases, a method for measuring cathepsin K activity, a method for measuring osteoclast activity, a method for diagnosing bone diseases, a composition for screening drugs inhibiting cathepsin K activity, and a method for screening drugs inhibiting cathepsin K activity. According to the present invention, rapidity and accuracy of diagnosis can be increased by designing a probe for measuring the activity of cathepsin K specifically expressed in osteoclasts, and thus the probe can be advantageously used for diagnosing bone diseases and screening cathepsin K activity-inhibiting drugs.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances

Abstract

Disclosed is a magnetic structure having a spike structure, the magnetic structure comprising: a core including at least one magnetic nanoparticle; a buffer disposed on an outer surface of the core; a shell disposed on an outer surface of the buffer, and at least one spike structure protruding outwardly from the shell, wherein the spike structure is controlled to have various shapes.

IPC Classes  ?

• H01F 1/00 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties

Abstract

Calliphora lataCalliphora vicinaTriceratopyga calliphoroidesLucilia illustrisLucilia caesarLucilia sericataChrysomya megacephalaChrysomya pinguisPhormia reginaPhormia regina (re), which belong to the family Calliphoridae; statistically analyzing the significance thereof to demonstrate that high accuracy is exhibited; and identifying that the classification index of species identification has low correlation with the degree of growth (body length) of larvae.

IPC Classes  ?

• G01N 33/483 - Physical analysis of biological material

Abstract

The present invention relates to a composition including a Propionibacterium freudenreichii MJ2 strain as an active ingredient for preventing, alleviating, or treating rheumatoid arthritis. The composition of the present invention is safe even when administered for a long period of time and restores autophagy to a normal level while inhibiting osteoclast differentiation, inflammatory reactions, apoptosis, and antibody production, and is thus expected to be variously used for drugs, quasi-drugs, functional foods, and the like for preventing, treating, and alleviating rheumatoid arthritis, which is an autoimmune disease.

IPC Classes  ?

• A61K 35/741 - Probiotics
• A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
• C12N 1/20 - BacteriaCulture media therefor

Abstract

The present invention relates to a protein including self-assembled ferritin monomers, in which a methane oxidation active domain, and an electron transfer domain including a flavin adenine dinucleotide (FAD)-binding domain are fused, and to: a protein which can oxidize methane by using NADH in vivo as a reducing agent, thus being capable of oxidizing methane to methanol without using a separate reducing agent; a microorganism expressing the same; a composition for producing methanol by using the same; and a method for producing methanol.

IPC Classes  ?

• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• C12P 7/04 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Abstract

The present invention relates to a method for manufacturing a thin film composite membrane for alkaline water electrolysis, and to a thin film composite membrane for alkaline water electrolysis. The present invention can provide a thin film composite membrane, which has excellent water electrolysis performance due to low mass transport resistance and high ion conductivity thereof compared to conventional nonporous membranes and porous membranes, and it is also highly safe by lowering gas permeability and minimizing gas mixing.

IPC Classes  ?

• C25B 13/02 - DiaphragmsSpacing elements characterised by shape or form
• C25B 13/08 - DiaphragmsSpacing elements characterised by the material based on organic materials

Abstract

The semiconductor substrate of the present invention may comprise a substrate and a semiconductor layer arranged on the substrate. Additional energy is supplied to sputtering in a thin film growth process step so that the semiconductor layer can be deposited. The additional energy can be at least one from among an ion beam, an electron beam, plasma, ultraviolet rays, a laser, and an LED light source. For example, the substrate can be a glass substrate, and the semiconductor layer can be a nitride semiconductor layer having a single-crystal plane. The semiconductor layer can be deposited by means of ion beam sputtering using the ion beam as the additional energy.

IPC Classes  ?

• H01L 33/32 - Materials of the light emitting region containing only elements of group III and group V of the periodic system containing nitrogen
• H01L 33/16 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a particular crystal structure or orientation, e.g. polycrystalline, amorphous or porous

Abstract

The present invention pertains to an anticancer composition containing IF1 (ATPase inhibitory factor 1). The IF1 (ATPase inhibitory factor 1) according to the present invention has the effect of releasing extracellular ATP, induces cytotoxicity in various cancer cells and exhibits anticancer efficacy, and is thus very useful as an active ingredient of a powerful anticancer agent.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A23L 33/17 - Amino acids, peptides or proteins
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to a composition for inhibiting teratoma formation or growth, comprising tissue inhibitor of metalloproteinase 1 (TIMP-1) or tissue inhibitor of metalloproteinase 2 (TIMP-2) as an effective component. A pharmaceutical composition for inhibiting teratoma formation or growth comprising TIMP-1 or TIMP-2 as an effective component according to the present invention, when used in stem cell therapy, can inhibit the formation and growth of teratomas caused by undifferentiated pluripotent stem cells, without affecting the differentiation potential thereof, and thus can be advantageously used as a combination drug in combination with a stem cell drug.

IPC Classes  ?

• A61K 38/57 - Protease inhibitors from animalsProtease inhibitors from humans
• A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
• A61K 35/545 - Embryonic stem cellsPluripotent stem cellsInduced pluripotent stem cellsUncharacterised stem cells

Abstract

The present disclosure may provide a CHA-DDR type zeolite membrane including: a first layer including a CHA structure and a DDR structure; and a second layer which is provided on the first layer and includes a DDR structure, wherein the CHA-DDR type zeolite membrane is in the form of a film having a thickness of 100 nm to 5 μm, including a CHA structure and a DDR structure.

IPC Classes  ?

• C01B 39/04 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereofDirect preparation thereofPreparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactantsAfter-treatment thereof using at least one organic template directing agent, e.g. an ionic quaternary ammonium compound or an aminated compound
• B01D 53/22 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 69/04 - Tubular membranes
• B01D 69/10 - Supported membranesMembrane supports
• B01D 71/02 - Inorganic material

Abstract

The present invention relates to a fabric-type titanium oxide (TiOx)-based porous water electrolysis electrode, a method for preparing the same, and a water electrolysis device comprising the same.

IPC Classes  ?

• C25B 11/053 - Electrodes comprising one or more electrocatalytic coatings on a substrate characterised by multilayer electrocatalytic coatings
• C23C 14/20 - Metallic material, boron or silicon on organic substrates
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/056 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material consisting of textile or non-woven fabric
• C25B 11/069 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material consisting of at least one single element and at least one compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the substrate or carrier material consisting of two or more compounds
• C25B 11/093 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds at least one noble metal or noble metal oxide and at least one non-noble metal oxide
• C25B 11/095 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds at least one of the compounds being organic
• C25B 11/097 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds comprising two or more noble metals or noble metal alloys
• C25D 3/12 - ElectroplatingBaths therefor from solutions of nickel or cobalt
• C25D 7/00 - Electroplating characterised by the article coated

Abstract

Propionibacterium freudenreichiiPropionibacterium freudenreichii strain.

IPC Classes  ?

• A61K 35/74 - Bacteria
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
• A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
• A23L 33/195 - Proteins from microorganisms

Abstract

The disclosed artificial tactile sensor device according to the present invention comprises: a first material unit having rigidity and elasticity; a second material unit having rigidity and elasticity equal to or different from those of the first material unit and being in close contact with the first material unit; a deformation unit disposed in a protrusion protruding from any one of the first and second material units toward the other at the interface between the first and second material units so as to be deformed by a stimulus input from any one of the first and second material units; and an electrode unit for electrically sensing deformation of the deformation unit. This structure enables the replication of the human tactile sense, thereby providing a high-performance tactile sensor capable of measuring stimulation coming from various directions such as vibration stimulation, shear stress, and the like.

IPC Classes  ?

• G01L 1/18 - Measuring force or stress, in general using properties of piezo-resistive materials, i.e. materials of which the ohmic resistance varies according to changes in magnitude or direction of force applied to the material
• G01L 5/162 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes for measuring several components of force using variations in ohmic resistance of piezoresistors

Abstract

Disclosed in the present application is a composition for alleviating renal functional impairment, comprising, as an active ingredient, milk-derived exosomes in which nucleic acid oligomers are encapsulated. The composition comprises milk-derived exosomes in which PTP1B siRNA is encapsulated. The composition provides the effects of reducing blood urea nitrogen and/or creatinine values having increased because of renal damage and/or reducing inflammatory responses in renal cells.

IPC Classes  ?

• A61K 9/50 - Microcapsules
• A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61K 35/20 - MilkWheyColostrum

Abstract

The present invention discloses a low-temperature nitrogen oxide adsorber based on a metal oxide-impregnated platinum/gamma-alumina catalyst and a method for preparing the same. According to the present invention, the present invention provides a method for preparing a passive nitrogen oxide adsorber for removing nitrogen oxide from a diesel engine, comprising the steps of: (a) impregnating a gamma-alumina support with an aqueous solution of the noble metal catalyst precursor and drying it repeatedly up to a preset number of times; (b) obtaining a noble metal/gamma-alumina catalyst by sintering at a predetermined temperature after step (a) is completed; (c) impregnating the noble metal/gamma-alumina catalyst with an aqueous solution of a metal oxide precursor and drying it repeatedly up to a preset number of times; and (d) preparing a passive nitrogen oxide adsorber composed of Ax-B/γ-alumina by sintering at a predetermined temperature after step (c) is completed, wherein the A is a noble metal catalyst, x is the mass percent of the noble metal catalyst, and the B is a metal.

IPC Classes  ?

• B01J 23/89 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with noble metals
• B01D 53/94 - Chemical or biological purification of waste gases of engine exhaust gases by catalytic processes
• B01J 21/04 - Alumina
• B01J 23/42 - Platinum
• B01J 23/63 - Platinum group metals with rare earths or actinides
• B01J 35/30 - Catalysts, in general, characterised by their form or physical properties characterised by their physical properties
• B01J 35/61 - Surface area
• B01J 35/63 - Pore volume
• B01J 37/02 - Impregnation, coating or precipitation
• B01J 37/08 - Heat treatment

Abstract

A vehicle is configured to provide a security function using an electronic key. A method includes receiving a vehicle control signal through an antenna device of the vehicle, extracting a scrambled timestamp sequence (STS) field in the vehicle control signal, dividing the extracted STS field into sub-fields, each of which has a predefined certain length, performing cross-correlation calculation of the divided sub-fields and sub-templates previously stored in storage of the vehicle, extracting times of arrival of the vehicle control signal from the results of performing the cross-correlation calculation, and determining the vehicle control signal as a normal signal when consistency of distribution locations of the times of arrival in the results of performing the cross-correlation calculation is greater than or equal to a predefined reference value and determining the vehicle control signal as an abnormal signal when the consistency is less than the predefined reference value.

IPC Classes  ?

• B60H 1/00 - Heating, cooling or ventilating devices
• B60R 25/24 - Means to switch the anti-theft system on or off using electronic identifiers containing a code not memorised by the user

Abstract

Disclosed in the present invention is an anode for a lithium secondary battery, comprising: a substrate containing at least one metal selected from the group consisting of Li, Cu, Ni, and Mo; and a double-layer structured electrode protective film disposed on at least one surface of the substrate. The anode for a lithium secondary battery of the present invention comprises a double-layer structured electrode protective film with asymmetrically controlled surface energy and thus can suppress the formation of lithium dendrites, and a manufacturing method for the anode for a lithium secondary battery of the present invention can easily achieve an enlargement of lithium secondary batteries through a simple modification process.

IPC Classes  ?

• H01M 4/66 - Selection of materials
• H01M 10/052 - Li-accumulators
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to molybdenum-based nanometal and a manufacturing method therefor. According to an embodiment of the present invention, molybdenum-based nanometal is formed, in a plating bath in which a porous frame is located having, located on one side thereof, a working electrode for an electrodeposition method, and, located on the opposite side of the one side, a counter electrode of the working electrode and in which a solution including a precursor, a buffering agent and an additive is used, by reducing molybdenum or by reducing molybdenum simultaneously with any one of cobalt, nickel and iron, in pores of the porous frame, on the basis of currents applied through the working electrode and the counter electrode, and then selectively removing from the porous frame, wherein specific resistance may be controlled on the basis of the buffering agent and the additive.

IPC Classes  ?

• C25D 1/00 - Electroforming
• C25D 5/18 - Electroplating using modulated, pulsed or reversing current
• C25D 3/56 - ElectroplatingBaths therefor from solutions of alloys
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

Provided is a fluid leak detection sensor system. The fluid leak detection sensor system includes: first and second electrodes spaced apart from each other; an absorption pad disposed between the first electrode and the second electrode to absorb a fluid; a first insulating tape disposed on the first electrode, and having a plurality of first holes; a second insulating tape disposed on the second electrode, and having a plurality of second holes; and an electronic unit control unit forming electrical contact points with the first electrode and the second electrode, wherein the electronic unit control unit includes: an alternating current signal generator; a peak detector circuit unit configured to measure a change in an impedance value between the first electrode and the second electrode according to the absorption of the fluid performed by the absorption pad; an electronic communication control unit; and a pair of pinch electrical connectors.

IPC Classes  ?

• G01M 3/18 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means for pipes, cables, or tubesInvestigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means for pipe joints or sealsInvestigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means for valves

Abstract

Disclosed are an apparatus and a method for estimating a user pose in a three-dimensional space. The apparatus includes a relative pose identification unit configured to identify estimated relative pose information between a plurality of images acquired in a chronological order in a real space; and a user pose estimating unit configured to: acquire a three-dimensional space model constructed using spatial information including at least one of inertial information, depth information, and image information about the real space; generate estimated pose candidate information based on the acquired three-dimensional space model; associate the identified estimated pose candidate information and the estimated relative pose information with each other; and estimate the user pose based on the association result.

IPC Classes  ?

• G06T 7/73 - Determining position or orientation of objects or cameras using feature-based methods
• G06V 10/74 - Image or video pattern matchingProximity measures in feature spaces
• G06V 10/762 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks

Abstract

An air conditioning device configured so that, in a circulation operation state, a first air passage connecting a first intake port and a first discharge port is formed to move indoor air through the first intake port, through a carbon dioxide suction filter, and through the first discharge port to the indoor area, and, in a ventilation operation state, a second air passage connecting the first intake port and a second discharge port is formed to move indoor air from through the first intake port, through the carbon dioxide suction filter, and through the second discharge port to the outdoor area while a heater heats the carbon dioxide suction filter, and a third air passage connecting a second intake port to the first discharge port is formed to move outdoor air from the outdoor area through the second intake port, and through the first discharge port to the indoor area.

IPC Classes  ?

• F24F 7/003 - Ventilation in combination with air cleaning
• F24F 7/08 - Ventilation with ducting systems with forced air circulation, e.g. by fan with separate ducts for supplied and exhausted air
• F24F 8/158 - Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering by chemical means using active carbon
• F24F 8/90 - Cleaning of purification apparatus

Abstract

Disclosed are a PAM-4 transceiver for capacitive-driven channels capable of canceling crosstalk and an operation method thereof. The PAM-4 transceiver includes a first channel that transmits and receives a PAM-4 signal generated based on a first input signal through a coupling capacitor disposed at a transmitting stage, and a second channel and a third channel disposed adjacent to the first channel, and the first channel includes a converter that receives a second input signal of the second channel and a third input signal of the third channel, and a cancellation circuit connected to the converter and that cancels a crosstalk occurring in the first channel due to the second input signal and the third input signal, and the cancellation circuit outputs a compensation signal corresponding to the crosstalk based on the second input signal and the third input signal.

IPC Classes  ?

• H04B 10/40 - Transceivers
• H04B 10/524 - Pulse modulation

Abstract

The present disclosure relates to a porous membrane and a method of manufacturing the same, and more particularly, to a thermally stable porous membrane capable of securing thermal stability and long-term stability of gas separation performance at high temperatures, and a manufacturing method thereof. This invention is related to a porous membrane comprising: a first Zeolitic Imidazolate Fragments (ZIFs) part formed on a surface of a porous support; and a second ZIFs part embedded in the porous support, wherein the second ZIFs part is formed in a state in which it penetrates from an interface between the first ZIFs part and the second ZIFs part to a predetermined depth.

IPC Classes  ?

• C01B 3/50 - Separation of hydrogen or hydrogen containing gases from gaseous mixtures, e.g. purification
• B01D 53/22 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranesMembrane supports
• B01D 69/14 - Dynamic membranes

Abstract

The present invention relates to: a gene editing composition comprising a guide RNA for editing mutated CAG repeat sequences of neural stem cells (ciNSCs) induced from somatic cells of a Huntington's disease patient; the edited ciNSCs; and a cell therapeutic agent for Huntington's disease, comprising same, wherein, in the edited ciNSCs, Huntington gene mutations are removed by the guide RNA of the present invention, and thus treatment for Huntington's disease and neuronal proliferation can be improved.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12N 9/22 - Ribonucleases
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61K 35/30 - NervesBrainEyesCorneal cellsCerebrospinal fluidNeuronal stem cellsNeuronal precursor cellsGlial cellsOligodendrocytesSchwann cellsAstrogliaAstrocytesChoroid plexusSpinal cord tissue
• A61P 25/14 - Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Abstract

Disclosed is an apparatus for classifying domain non-specific images using text according to one embodiment of the present invention. According to the present invention, the learning process is performed not only using the images but also text information together, and thus even during training on images from only a few specific domains, it is possible to effectively classify the images from different domains with high accuracy by applying the human inference process.

IPC Classes  ?

• G06V 10/80 - Fusion, i.e. combining data from various sources at the sensor level, preprocessing level, feature extraction level or classification level
• G06F 40/284 - Lexical analysis, e.g. tokenisation or collocates
• G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
• G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
• G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
• G06V 10/776 - ValidationPerformance evaluation
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks

Abstract

The present invention relates to a peptide having obesity and muscle loss inhibitory activities, and a use thereof. The peptide has excellent effects on suppressing appetite, promoting energy metabolism, inhibiting fat accumulation, and promoting lipolysis, and inhibits muscle atrophy while promoting muscle synthesis, such that the peptide can be effectively used for the prevention or treatment of obesity and sarcopenia.

IPC Classes  ?

• A61K 38/08 - Peptides having 5 to 11 amino acids
• A61K 38/06 - Tripeptides
• A61K 38/10 - Peptides having 12 to 20 amino acids
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 3/04 - AnorexiantsAntiobesity agents
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system

Abstract

Disclosed is a stateful logic-in-memory using silicon diodes. More particularly, the stateful logic-in-memory according to an embodiment of the present invention includes a plurality of silicon diodes, each of the silicon diodes includes an anode region, a first channel region, a second channel region and a cathode region and is included as a memory cell.

IPC Classes  ?

• G11C 11/36 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using electric elements using semiconductor devices using diodes, e.g. as threshold elements
• H03K 19/20 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits characterised by logic function, e.g. AND, OR, NOR, NOT circuits
• H03K 19/21 - EXCLUSIVE-OR circuits, i.e. giving output if input signal exists at only one inputCOINCIDENCE circuits, i.e. giving output only if all input signals are identical
• H10B 99/00 - Subject matter not provided for in other groups of this subclass

Abstract

The present disclosure relates to a three-dimensional (3D) data augmentation method using a weighted local transformation and an apparatus for the same. More specifically, the present disclosure relates to a method and apparatus of significantly augmenting 3D data required to improve the performance of an artificial intelligence model with only limited 3D data by applying a non-rigid transformation to local part(s) of the 3D data.

IPC Classes  ?

• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• G06T 5/70 - DenoisingSmoothing
• G06T 7/11 - Region-based segmentation

Abstract

A condensed cyclic compound represented by Formula 1, an organic photodetector including the condensed cyclic compound. and an electronic apparatus including the organic photodetector are provided: A condensed cyclic compound represented by Formula 1, an organic photodetector including the condensed cyclic compound. and an electronic apparatus including the organic photodetector are provided:

IPC Classes  ?

• H10K 85/60 - Organic compounds having low molecular weight
• C07D 495/04 - Ortho-condensed systems
• C07D 495/14 - Ortho-condensed systems
• H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers

Abstract

The present invention relates to a composition for preparing a solid electrolyte including a polyrotaxane compound, a cross-linking agent, a lithium salt, and an organic solvent, wherein the cross-linking agent includes a compound represented by Formula 1 below and a compound represented by Formula 2, a method for preparing a solid electrolyte for a lithium secondary battery including thermal-curing the composition for preparing a solid electrolyte, a solid electrolyte for a lithium secondary battery including a thermo-cured product of the composition for preparing a solid electrolyte, and a lithium secondary battery including the solid electrolyte.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

Abstract

The present invention relates to a cosmetic composition containing Zn-porphyrin and lignin for blocking ultraviolet rays. The cosmetic composition for blocking ultraviolet rays, according to the present invention, can effectively block UV-A and UV-B, which are harmful to the human body and, compared to when Zn-porphyrin or lignin alone is used, has significantly increased ultraviolet blocking efficiency.

IPC Classes  ?

• A61K 8/27 - ZincCompounds thereof
• A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
• A61K 8/72 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
• A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations

Abstract

Disclosed is a hybrid water-treating system. The system includes a raw-water supply bath having a predetermined volume and configured to receive raw-water containing high concentration organic contaminants; at least one electrolytic bath configured to receive the raw-water supplied from the raw-water supply bath and to produce first treated water, wherein a boron doped diamond (BDD) electrode is installed in the electrolytic bath; and at least one deionization bath configured to receive the first treated water discharged from the electrolytic bath and to produce second treated water, wherein flow-electrode capacitive deionization (FCDI) is performed when applying a first voltage to the deionization bath.

IPC Classes  ?

• C02F 1/461 - Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
• B01D 61/42 - ElectrodialysisElectro-osmosis
• C02F 1/467 - Treatment of water, waste water, or sewage by electrochemical methods by electrolysis by electrochemical disinfection
• C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
• C02F 101/12 - Halogens or halogen-containing compounds
• C02F 101/30 - Organic compounds
• C02F 103/08 - Seawater, e.g. for desalination

Abstract

The present invention relates to an AR-based orthodontic assistance system. The system may comprise: an imaging device for acquiring a 3D image of the teeth of a patient by using three-dimensional digital photography; a database unit for storing a target teeth model in which a target teeth arrangement generated on the basis of the 3D image of the teeth is imaged; AR glasses having a camera, which photographs the teeth of the patient so as to acquire a 2D image of the teeth, and a display, which displays a virtual image showing the teeth of the patient to be superimposed on the real world; a matching unit for generating the virtual image by matching the target teeth model and the 2D image; a marker-mounted module which is fitted into both nostrils of the patient for the matching and on which a plurality of markers are mounted; and a stereo camera for photographing the plurality of markers in order to generate reference coordinates for the matching.

IPC Classes  ?

• A61C 7/00 - Orthodontics, i.e. obtaining or maintaining the desired position of teeth, e.g. by straightening, evening, regulating, separating, or by correcting malocclusions
• A61C 9/00 - Impression methods specially adapted for dental prostheticsImpression cups therefor
• A61C 19/04 - Measuring instruments specially adapted for dentistry
• A61C 13/00 - Dental prosthesesMaking same
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
• G06T 1/00 - General purpose image data processing
• G06T 17/00 - 3D modelling for computer graphics
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G16H 30/00 - ICT specially adapted for the handling or processing of medical images