Abstract

An emulsion spectrum fluid filter capable of controlling light wavelength absorption includes a transparent channel formed as a tube of a 90 degrees-rotated U shape, and an emulsion received in the transparent channel, wherein the emulsion may include dispersed oil and surfactant. Further, a method for preparing the emulsion is disclosed.

IPC Classes  ?

• H10F 77/63 - Arrangements for cooling directly associated or integrated with photovoltaic cells, e.g. heat sinks directly associated with the photovoltaic cells or integrated Peltier elements for active cooling
• G02B 5/24 - Liquid filters
• H10F 77/45 - Wavelength conversion means, e.g. by using luminescent material, fluorescent concentrators or up-conversion arrangements

Abstract

An apparatus, method, and system for displaying an ultrasound image based on mixed reality are described. The method of displaying an ultrasound image based on mixed reality according to an exemplary embodiment includes obtaining the ultrasound image captured through an ultrasound device; obtaining localization information of a probe of the ultrasound device; converting the ultrasound image into a composite image to be output based on the mixed reality; and outputting the composite image by overlaying the composite image on a reference image captured to include the probe.

IPC Classes  ?

• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• A61B 90/50 - Supports for surgical instruments, e.g. articulated arms
• G06T 7/13 - Edge detection
• G06T 7/90 - Determination of colour characteristics
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts

Abstract

The present invention relates to: a chromene-benzimidazole derivative or a pharmaceutically acceptable salt thereof; and a composition for preventing or treating cancer, the composition containing said derivative as an active ingredient. The chromene-benzimidazole derivative of the present invention is activated in cancer cells to inhibit tubulin polymerization, and suppresses the C-terminal domain of Hsp90, and thus can arrest the cell cycle of the cancer cells and induce apoptosis as well as inhibit the activity of oncoproteins when administered to a subject. Therefore, the chromene-benzimidazole derivative of the present invention can be used as a new dual-target anticancer drug for preventing or treating cancer, preferably for preventing or treating triple-negative breast cancer.

IPC Classes  ?

• C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
• A61K 31/427 - Thiazoles not condensed and containing further heterocyclic rings
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61P 35/00 - Antineoplastic agents
• C07D 235/32 - Benzimidazole-2-carbamic acids, unsubstituted or substitutedEsters thereofThio-analogues thereof
• C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Abstract

The present invention relates to a method for culturing microalgae by using air. The method for culturing microalgae according to an embodiment of the present invention, in which microalgae is cultured inside a reactor, comprises: a step for adding a growth medium and limestone to the inside of the reactor; a step for supplying air to the inside of the reactor to which the growth medium and limestone were added, the air being supplied using an air pump; and a step for inoculating microalgae inside the reactor supplied with air, and growing the microalgae by performing a first photo-culture.

IPC Classes  ?

• C12N 1/12 - Unicellular algaeCulture media therefor
• C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound
• C12M 1/00 - Apparatus for enzymology or microbiology
• C12R 1/89 - Algae

Abstract

Provided is an operating method of a processing circuit, the method including generating a first compressed chunk including only a first valid value, generating a first mask includes a reference value at a same position as a position of the first valid value, and includes a plurality of first sub-masks, generating a second compressed chunk including only a second valid value, generating a second mask, includes a reference value at a same position as a position of the second valid value, and includes a plurality of second sub-masks, generating a valid pair position value for each of a current first sub-mask and a current second sub-mask, generating a first cumulative value corresponding to a number of reference values included in a first previous sub-mask, and generating a second cumulative value corresponding to a number of reference values included in a second previous sub-mask.

IPC Classes  ?

• G06F 9/30 - Arrangements for executing machine instructions, e.g. instruction decode

Abstract

The present invention provides a high-performance gas classification artificial intelligence system and a gas classification method using same. The high-performance gas classification artificial intelligence system according to the present invention comprises at least one gas sensor, and a gas classification server based on an artificial neural network, wherein the gas classification server includes: a reception unit for receiving gas sensing data from the gas sensor; a pre-processing unit for pre-processing the gas sensing data; and a target gas classification unit for classifying the type and concentration of target gas by inputting the pre-processed gas sensing data into a gas classification model based on the artificial neural network, the gas sensing data is a current signal over time, and the pre-processing unit includes a data processing unit for deriving first differential data and second differential data with respect to the time of the current signal, and calculating processed data by using the first differential data and the second differential data.

IPC Classes  ?

• G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
• G06N 3/09 - Supervised learning

Abstract

The present disclosure provides an artificial lens fixing sac for fixing an artificial lens for cataract surgery. The artificial lens fixing sac for fixing an artificial lens for cataract surgery of the present disclosure is installed at a position of a lens that is removed by cataract surgery, and the artificial lens fixing sac includes an implantation hole in which an artificial lens, which is inserted into an internal space of the artificial lens fixing sac, is implanted at the position of the removed lens, and fixing threads installed at predetermined intervals on an outer peripheral edge of the artificial lens fixing sac to fix the artificial lens fixing sac to a sclera.

IPC Classes  ?

• A61F 2/16 - Intraocular lenses
• A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents

Abstract

Disclosed are an imaging device for correcting and reconstructing a target image in a scattering medium using a multiple scattering tracing algorithm based on a reflection matrix and a method thereof. According to an embodiment of the present disclosure, the imaging device corrects and reconstructs an image of a target object located deep inside a scattering medium such as a biological tissue by tracing a multiple scattering trajectory using a time-resolved reflection matrix obtained from an imaging device that uses a time-resolved light source and then correcting it.

IPC Classes  ?

• G01N 21/47 - Scattering, i.e. diffuse reflection
• G01N 33/02 - Food
• G01N 33/483 - Physical analysis of biological material
• G06T 5/80 - Geometric correction

Abstract

The present invention relates to an artificial tooth recommendation method implemented by a computing apparatus, and the artificial tooth recommendation method comprises the steps of: receiving image data as an input; generating corresponding mesh data from the input image data; generating feature data from the generated mesh data by using a machine learning-based feature data generation unit; generating type data or size data from the generated feature data by using a machine learning-based type and size data generation unit; and generating recommended artificial tooth appearance data corresponding to the type data or the size data by using a machine learning-based recommended artificial tooth appearance data generation unit.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
• G06V 40/16 - Human faces, e.g. facial parts, sketches or expressions
• G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• G06N 20/20 - Ensemble learning
• G06T 17/20 - Wire-frame description, e.g. polygonalisation or tessellation
• A61C 13/00 - Dental prosthesesMaking same
• A61C 9/00 - Impression methods specially adapted for dental prostheticsImpression cups therefor
• A61C 19/04 - Measuring instruments specially adapted for dentistry

Abstract

Disclosed is an electronic device. The electronic device comprises: a memory for storing at least one instruction; and one or more processors that individually and/or collectively include processing circuits, identify a foreground region and a background region included in an input image on the basis of a depth map corresponding to the input image, and convert a viewpoint on the basis of the foreground region to generate a new viewpoint image. The one or more processors: identify, on the basis of the depth map, side effect prediction information including at least one of whether objects of at most a specific thickness are included in the input image or how densely concentrated the objects are; and generate the new viewpoint image by controlling a viewpoint movement path on the basis of the identified side effect prediction information.

IPC Classes  ?

• H04N 13/117 - Transformation of image signals corresponding to virtual viewpoints, e.g. spatial image interpolation the virtual viewpoint locations being selected by the viewers or determined by viewer tracking
• H04N 13/128 - Adjusting depth or disparity
• G06T 7/194 - SegmentationEdge detection involving foreground-background segmentation
• G06T 5/77 - RetouchingInpaintingScratch removal

Abstract

Disclosed is an inference model selection method and apparatus considering a task request rate. The inference model selection method is performed by a computing device including a processor and includes monitoring computing resources of the computing device; receiving a task; selecting an inference model to perform inference for the received task; inputting the task into a queue of the selected inference model; and performing an inference operation.

IPC Classes  ?

• G06N 5/04 - Inference or reasoning models

Abstract

Provided is an electronic device for factorization of a target number. The electronic device includes an energy calculating circuit configured to generate input values for updating bits of a candidate number based on an energy function that has a minimum when the candidate number is a factor of the target number, and bit updating circuits corresponding to the bits of the candidate number, respectively.

IPC Classes  ?

• G06F 17/11 - Complex mathematical operations for solving equations
• G06F 5/01 - Methods or arrangements for data conversion without changing the order or content of the data handled for shifting, e.g. justifying, scaling, normalising

Abstract

Provided are a method for producing a self-healing polymer, which includes A) allowing polytetramethylene glycol (PTMG) and diisocyanate to react with each other at a first temperature, B) B) adding dimethylglyoxime (DMG) serving as a chain extender, which is melted in tetrahydrofuran (THF) serving as a solvent, to react with the reaction product in A) at a second temperature lower than the first temperature, C) reducing a temperature of a reaction product in B) to a third temperature lower than the second temperature and adding polydimethylsiloxane (PDMS), which is melted in THF to make a reaction, D) adding a crosslinker, which is melted in THF, to a reaction product in C) and stirring the result, and E) obtaining a polymer cured as the solvent is removed from a reaction product in D), the self-healing polymer produced through the method, and an electronic device including the self-healing polymer.

IPC Classes  ?

• C08G 65/34 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives

Abstract

An embodiment opening and closing apparatus of a sliding door of a vehicle includes a carrier slidably installed along a lengthwise direction of the vehicle, a pair of links rotatably installed on the carrier and spaced apart from each other, wherein a first end portion of the pair of links is hinge-connected to the sliding door of the vehicle, and a popping-out device configured to pop the sliding door out of a vehicle body of the vehicle by rotating the pair of links during an initial stage of an opening operation of the sliding door.

IPC Classes  ?

• E05F 15/655 - Power-operated mechanisms for wings using electrical actuators using rotary electromotors for horizontally-sliding wings specially adapted for vehicle wings
• E05F 15/649 - Power-operated mechanisms for wings using electrical actuators using rotary electromotors for horizontally-sliding wings operated by swinging arms
• E05F 15/652 - Power-operated mechanisms for wings using electrical actuators using rotary electromotors for horizontally-sliding wings operated by screw-and-nut mechanisms

Abstract

The present invention relates to a light emitting device-thin film transistor integration structure and a manufacturing method therefor, the integration structure, according to one embodiment, comprising: a thin film transistor formed on a substrate; an upper insulating layer formed on the thin film transistor; an upper electrode formed on the upper insulating layer; a micro-hole formed in regions of the upper electrode and upper insulating layer corresponding to a first electrode of the thin film transistor, so as to expose a preset region of the first electrode to the outside; and a light emitting device formed in the micro-hole so as to be electrically connected to the first electrode.

IPC Classes  ?

• H01L 25/075 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
• H01L 33/62 - Arrangements for conducting electric current to or from the semiconductor body, e.g. leadframe, wire-bond or solder balls
• H01L 27/12 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being other than a semiconductor body, e.g. an insulating body
• H01L 33/20 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a particular shape, e.g. curved or truncated substrate
• H01L 23/00 - Details of semiconductor or other solid state devices
• H01L 33/46 - Reflective coating, e.g. dielectric Bragg reflector
• H01L 33/52 - Encapsulations

Abstract

The present disclosure relates to an ultra-small laser oscillator utilizing self-resonance in a pattered indirect bandgap material. The ultra-small laser oscillator using self-resonance according to an embodiment may include a substrate; and a resonator that is formed of transition metal dichalcogenides (TMDs) on the substrate, supports a whispering gallery mode (WGM), and performs lasing in a form of a continuous wave at room temperature.

IPC Classes  ?

• H01S 5/10 - Construction or shape of the optical resonator

Abstract

The transmitter includes a driver that is connected to an output node and drives the output node with a pulse amplitude modulation-4 (PAM-4) signal having four levels of a most significant bit (MSB) and a least significant bit (LSB), and an equalizer that is connected to the output node and compensates for attenuation of the PAM-4 signal based on a first operating voltage, wherein the equalizer compensates for the attenuation based on applying a second operating voltage having a level greater than a level of the first operating voltage to the output node when a transition from a first level to a second level among the four levels is a rising transition, and compensates for the attenuation based on forming a path for extracting an equalizing current from the output node when the transition from the first level to the second level is a falling transition.

IPC Classes  ?

• H04L 25/03 - Shaping networks in transmitter or receiver, e.g. adaptive shaping networks
• H03K 5/00 - Manipulation of pulses not covered by one of the other main groups of this subclass
• H03K 17/56 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices
• H04L 25/49 - Transmitting circuitsReceiving circuits using code conversion at the transmitterTransmitting circuitsReceiving circuits using predistortionTransmitting circuitsReceiving circuits using insertion of idle bits for obtaining a desired frequency spectrumTransmitting circuitsReceiving circuits using three or more amplitude levels

Abstract

A semiconductor memory device is provided. The semiconductor device includes: a word line extending in a lateral direction; a sensing line apart from the word line, the sensing line overlapping the word line in a vertical direction and extending in the lateral direction; a vertical semiconductor structure passing through the word line and the sensing line in the vertical direction, the vertical semiconductor structure having a vertical channel region facing the word line in the lateral direction; and a gate dielectric film between the vertical channel region and the word line. The vertical semiconductor structure includes a first heavily doped film of a first conductivity type, a first lightly doped film of a second conductivity type, a second lightly doped film of the first conductivity type, and a second heavily doped film of the second conductivity type, which are sequentially provided in the vertical direction.

IPC Classes  ?

• H10B 12/00 - Dynamic random access memory [DRAM] devices

Abstract

A processor-implemented method including detecting pieces of text from an image, determining vanishing points of the image, and estimating an orientation of the image based on the determined vanishing points, the detected pieces of text, and a key text graph representing a connection between nodes corresponding to pieces of key text.

IPC Classes  ?

• G06T 7/73 - Determining position or orientation of objects or cameras using feature-based methods
• G06T 7/536 - Depth or shape recovery from perspective effects, e.g. by using vanishing points
• G06V 20/58 - Recognition of moving objects or obstacles, e.g. vehicles or pedestriansRecognition of traffic objects, e.g. traffic signs, traffic lights or roads
• G06V 20/62 - Text, e.g. of license plates, overlay texts or captions on TV images
• G06V 30/18 - Extraction of features or characteristics of the image
• G06V 30/19 - Recognition using electronic means

Abstract

The present invention relates to a technology for an atoliter reaction chamber array that prevents unwanted light reflections, thereby reducing errors during the photochemical-based DNA synthesis process. Utilizing the array allows for a reduction in DNA synthesis errors and the consumption of samples.

IPC Classes  ?

• B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves

Abstract

A device for evaluating integrity of an underground structure by using electromagnetic waves includes a plurality of main reinforcing bars arranged in a vertical direction in an underground structure, a plurality of measurement cables extending vertically to be adjacent to the main reinforcing bars, respectively, at least one impedance change unit which is provided on each of the measurement cables, is electrically connected to the measurement cable, and has a characteristic impedance different from a characteristic impedance of the measurement cable, and an electromagnetic wave measurement unit for detecting a change point of a characteristic impedance as a defect point of the underground structure by providing an electromagnetic wave by using, as a signal transmission line, one of the plurality of measurement cables and one of the plurality of main reinforcing bars, or one pair of measurement cables selected from the plurality of measurement cables.

IPC Classes  ?

• E02D 33/00 - Testing foundations or foundation structures
• G01R 27/16 - Measuring impedance of element or network through which a current is passing from another source, e.g. cable, power line
• G01V 3/12 - Electric or magnetic prospecting or detectingMeasuring magnetic field characteristics of the earth, e.g. declination or deviation operating with electromagnetic waves

Abstract

Disclosed are a perovskite quantum dot-based indoor photovoltaic cell and a manufacturing method thereof. A perovskite quantum dot-based indoor photovoltaic cell includes a transparent lower electrode layer through which indoor light passes; a photoactive layer that generates excitons by the indoor light and separates the excitons into positive and negative charges; and an upper electrode layer that absorbs the negative charge, wherein the photoactive layer is formed of a perovskite quantum dot.

IPC Classes  ?

• H10K 30/50 - Photovoltaic [PV] devices
• H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
• H10K 30/85 - Layers having high electron mobility, e.g. electron-transporting layers or hole-blocking layers
• H10K 85/60 - Organic compounds having low molecular weight

Abstract

Provided is a steel reinforcement including an amount of 0.07 to 0.43 wt % of carbon (C), an amount of 0.5 to 2.0 wt % of manganese (Mn), an amount of 0.05 to 0.5 wt % of silicon (Si), an amount greater than 0 and less than or equal to 0.5 wt % of chromium (Cr), an amount greater than 0 and less than or equal to 4.5 wt % of copper (Cu), an amount greater than 0 and less than or equal to 0.003 wt % of boron (B), an amount greater than 0 and less than or equal to 0.25 wt % of vanadium (V), an amount greater than 0 and less than or equal to 0.012 wt % of nitrogen (N), an amount greater than 0 and less than or equal to 0.03 wt % of phosphorus (P), an amount greater than 0 and less than or equal to 0.03 wt % of sulfur(S), an amount of 0.01 to 0.5 wt % of the sum of one or more of nickel (Ni), niobium (Nb) and titanium (Ti), the balance of iron (Fe), and other inevitable impurities. A final microstructure includes ferrite, bainite, pearlite, retained austenite, and precipitates comprising copper.

IPC Classes  ?

• C22C 38/32 - Ferrous alloys, e.g. steel alloys containing chromium with boron
• C21D 8/02 - Modifying the physical properties by deformation combined with, or followed by, heat treatment during manufacturing of plates or strips
• C21D 8/06 - Modifying the physical properties by deformation combined with, or followed by, heat treatment during manufacturing of rods or wires
• C22C 38/00 - Ferrous alloys, e.g. steel alloys
• C22C 38/02 - Ferrous alloys, e.g. steel alloys containing silicon
• C22C 38/04 - Ferrous alloys, e.g. steel alloys containing manganese
• C22C 38/20 - Ferrous alloys, e.g. steel alloys containing chromium with copper
• C22C 38/24 - Ferrous alloys, e.g. steel alloys containing chromium with vanadium
• C22C 38/26 - Ferrous alloys, e.g. steel alloys containing chromium with niobium or tantalum
• C22C 38/28 - Ferrous alloys, e.g. steel alloys containing chromium with titanium or zirconium
• C22C 38/40 - Ferrous alloys, e.g. steel alloys containing chromium with nickel

Abstract

A method and apparatus with neural network based image processing are provided. The method includes: accessing an input image set including a visible light image of a visible light wavelength band corresponding to an input image and an infrared image of an infrared wavelength band corresponding to the input image; estimating an illumination map representing an illumination configuration of the input image based on a first input image set of the input image set; estimating a confidence score map of the input image based on spectral information of a second input image set of the input image set; and determining illuminant information of the input image by combining the illumination map and the confidence score map.

IPC Classes  ?

• G06V 10/60 - Extraction of image or video features relating to illumination properties, e.g. using a reflectance or lighting model
• G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks

Abstract

The present invention relates to a quinazoline-benzimidazole derivative or a pharmaceutically acceptable salt thereof and a composition comprising the derivative as an active ingredient for preventing or treating cancer. The quinazoline-benzimidazole derivative of the present invention is activated in cancer cells to inhibit tubulin polymerization and tyrosine kinase activity of the human epidermal growth factor receptor 2 (HER2). Upon administration to a subject, the derivative can arrest the cell cycle of cancer cells, induce apoptosis, and block cell growth signals transmitted via the HER2 receptor. Therefore, the derivative can be used as a dual-target anticancer drug for the prevention or treatment of cancer, particularly HER2-positive breast cancer or triple-negative breast cancer.

IPC Classes  ?

• C07D 403/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
• A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 35/00 - Antineoplastic agents
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Abstract

The present invention relates to an optical fiber-based DNA synthesis device capable of uniform light irradiation to an area where DNA is to be synthesized in a photochemical-based DNA synthesis process, and parallel DNA synthesis, wherein optical fiber strands are used as a light homogenizer and a DNA synthesis substrate.

IPC Classes  ?

• B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus
• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves

Abstract

Bacillus licheniformisAspergillus oryzaeAspergillus oryzae, or a combination thereof, and a method for preparing same. By utilizing the low-allergenic whey protein hydrolysate of the present invention, whey protein with high nutritional value can be consumed without the risk of causing an allergic reaction to milk.

IPC Classes  ?

• A23J 3/34 - Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
• C12P 21/06 - Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
• A23L 33/18 - PeptidesProtein hydrolysates
• C07K 1/12 - General processes for the preparation of peptides by hydrolysis
• A23J 1/20 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from milk, e.g. caseinObtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from whey
• A23J 3/08 - Dairy proteins

Abstract

One aspect of the present disclosure may provide a polyurethane-based coating material and a coating solution comprising same, wherein the polyurethane-based coating material ensures mechanical rigidity on the basis of a polyurethane material and simultaneously induces super-hydrorepellent properties, thereby achieving antifouling and antibacterial properties. The anti-fouling coating solution according to an embodiment of the present invention may include fluorine-containing polyurethane polymer (FPU), fluorine-containing urethane monomer (FU), and polytetrafluoroethylene (PTFE).

IPC Classes  ?

• C09D 175/04 - Polyurethanes
• C09D 5/16 - Anti-fouling paintsUnderwater paints
• C09D 7/80 - Processes for incorporating ingredients
• C08L 27/18 - Homopolymers or copolymers of tetrafluoroethene
• C08G 18/28 - Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
• C08G 18/38 - Low-molecular-weight compounds having hetero atoms other than oxygen

Abstract

The present disclosure relates to a binarized neural network circuitry using silicon-gated diodes. The binarized neural network circuitry according to one embodiment of the present disclosure includes a plurality of silicon-gated diodes in which a diode structure as a channel area is located between an anode terminal and a cathode terminal, a gate terminal is located on the diode structure to implement unidirectional switching through potential barrier control in the channel area based on different voltages applied to each of the anode terminal and the gate terminal, and memory characteristics are realized as holes or electrons accumulate in the potential well due to a positive feedback loop. In addition, in the binarized neural network circuitry, the silicon-gated diodes operate as synaptic elements in a memory array connected in parallel, and the results of a multiply-accumulate (MAC) operation are output based on an input signal applied from an input line processor connected to the memory array and a weight update signal applied from a synapse line processor connected to the memory array.

IPC Classes  ?

• G06N 3/065 - Analogue means
• G06N 3/04 - Architecture, e.g. interconnection topology

Abstract

The present invention discloses a wavelength self-filtering ultra-low noise near infrared quantum dot photodiode manufacturing method and a near infrared quantum dot photodiode manufactured thereby. According to the present invention, a near infrared (NIR) quantum dot photodiode includes: a transparent electrode through which visible light and near-infrared light pass; a p-type layer that is formed on the transparent electrode to shield the visible light; a quantum dot light absorption layer that is formed on the p-type layer to a preset thickness or more to generate excitons through the near-infrared light; an n-type layer that moves negative charges generated by the excitons; and an upper electrode that is formed on the n-type layer.

IPC Classes  ?

• H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
• B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
• H10K 30/82 - Transparent electrodes, e.g. indium tin oxide [ITO] electrodes
• H10K 71/60 - Forming conductive regions or layers, e.g. electrodes

Abstract

Disclosed is a computing-in-memory device, which includes a memory cell array including a plurality of local arrays that generates a first output signal and a second output signal by performing a multiply-accumulate (MAC) operation on an input signal applied through a plurality of operation word lines and a stored weight, a reference voltage generator that generates a reference voltage by sharing charges of the first output signal with adjacent global bit lines, and an analog-to-digital converter that compares the reference voltage with the second output signal and converts the second output signal into a digital signal based on a result of the comparison.

IPC Classes  ?

• G11C 11/419 - Read-write [R-W] circuits
• G06F 7/544 - Methods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using non-contact-making devices, e.g. tube, solid state deviceMethods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using unspecified devices for evaluating functions by calculation
• G11C 11/412 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using electric elements using semiconductor devices using transistors forming cells with positive feedback, i.e. cells not needing refreshing or charge regeneration, e.g. bistable multivibrator or Schmitt trigger using field-effect transistors only

Abstract

A piezoelectric material composition may be represented by Equation 1. A piezoelectric device may include a piezoelectric device layer including the piezoelectric material composition represented by Equation 1, a first electrode disposed at a first surface of the piezoelectric device layer, and a second electrode disposed at a second surface different from the first surface of the piezoelectric device layer. A piezoelectric material composition may be represented by Equation 1. A piezoelectric device may include a piezoelectric device layer including the piezoelectric material composition represented by Equation 1, a first electrode disposed at a first surface of the piezoelectric device layer, and a second electrode disposed at a second surface different from the first surface of the piezoelectric device layer. a ⁢ PbZrO 3 - b ⁢ PbTiO 3 - ( 1 - a - b ) ⁢ Pb ( Ni c ⁢ Nb 1 - c ) ⁢ O 3 + x ⁢ mol ⁢ % ⁢ A + y ⁢ vol ⁢ % ⁢ BaTiO 3 [ Equation ⁢ 1 ] where A is Fe2O3, Co2O3, Mn2O3, ZnO, GeO2, CuO, or NiO, and 0.15≤a≤0.24, 0.29≤b≤0.38, 0.30≤c≤0.35, 0.00≤x≤3.00, and 0.00≤y≤7.00.

IPC Classes  ?

• H10N 30/853 - Ceramic compositions
• C04B 35/468 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on titanium oxides or titanates based on titanates based on alkaline earth metal titanates based on barium titanates
• C04B 35/64 - Burning or sintering processes
• H10N 30/092 - Forming composite materials
• H10N 30/097 - Forming inorganic materials by sintering

Abstract

The present application relates to a composition for a non-aqueous electrolyte, comprising a mixed solvent and optionally comprising dual lithium salts, and to an electrochemical cell comprising the composition.

IPC Classes  ?

• H01M 10/0569 - Liquid materials characterised by the solvents
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/052 - Li-accumulators

Abstract

Provided is a method for manufacturing a diffractive optical element. The method for manufacturing a diffractive optical element may comprise: a step for preparing an imprinting stamp including a stamp pattern in which peaks and valleys having a curved shape are alternately and repeatedly arranged; a step for preparing a base structure in which a coating layer including a photocurable polymer and nanoparticles is formed on a base substrate; and a step for applying pressure to the coating layer of the base structure using the imprinting stamp to form, in the coating layer, a base pattern having the inverse image of the stamp pattern.

IPC Classes  ?

• G02B 5/18 - Diffracting gratings
• C07C 245/08 - Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with the two nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings, e.g. azobenzene

Abstract

The present invention relates to exosome-derived biomarkers for diagnosing arteriosclerosis. The biomarkers of the present invention exhibit specific changes in expression associated with arteriosclerosis, particularly during the early stages of the disease, and thus are highly effective for early diagnosis and prognosis of arteriosclerosis. Particularly, the 3D arteriosclerosis model of the present invention closely mimics the arterial condition of actual patients, allowing for the combined use of the biomarkers and the model to enable early diagnosis, personalized treatment development, and precise monitoring of disease prognosis.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

An embodiment of the present disclosure relates to a method for optimizing beam-pointing in a wireless optical communication system may comprise receiving, from an optical reception device by an optical transmission device, information related to power of a light, which is transmitted from a specific transmission terminal among one or more transmission terminals of the optical transmission device and is received by one or more reception terminals of the optical reception device on the basis of coordinate values associated with the one or more reception terminals; determining, by the optical transmission device, coordinate values which maximize a signal-to-noise ratio on the basis of the determined power of the received light; and transmitting a beam from the specific transmission terminal toward the optical reception device by the optical transmission device on the basis of the determined coordinate values.

IPC Classes  ?

• H04B 10/112 - Line-of-sight transmission over an extended range
• H04B 10/079 - Arrangements for monitoring or testing transmission systemsArrangements for fault measurement of transmission systems using an in-service signal using measurements of the data signal

Abstract

A generative inter-subject transfer learning apparatus includes: a data input unit for receiving source data and target data; a preprocessing unit for removing outliers from the source data and augmenting data; a first encoding unit for generating a feature vector of the source data received from the preprocessing unit and a feature vector of the target data; a generation unit for generating transfer data by reconfiguring the feature vector of the source data, and trained so that a domain of the source data follows a domain of the target data; a second encoding unit for generating a feature vector of the transfer data; and a classification unit for classifying the feature vector of the transfer data generated by the second encoding unit, and trained so that a classification result of the transfer data matches a classification result of the source data.

IPC Classes  ?

• G06N 3/096 - Transfer learning
• A61B 5/372 - Analysis of electroencephalograms

Abstract

The present invention relates to a dehydroaromatization catalyst and a preparation method thereof, the dehydroaromatization catalyst comprising the steps of: dealuminating zeolite by hydrothermal treatment at a first temperature; and supporting molybdenum (Mo) on the dealuminated zeolite.

IPC Classes  ?

• B01J 37/10 - Heat treatment in the presence of water, e.g. steam
• B01J 29/48 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereof of the pentasil type, e.g. types ZSM-5, ZSM-8 or ZSM-11 containing arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
• B01J 35/40 - Catalysts, in general, characterised by their form or physical properties characterised by dimensions, e.g. grain size
• B01J 37/02 - Impregnation, coating or precipitation
• B01J 37/12 - Oxidising

Abstract

The present invention relates to a method of preparing a culture broth of neural stem cells, having excellent abilities of reducing skin wrinkles or increasing skin elasticity, the culture broth comprising high concentrations of TIMP-1 and TIMP-2 capable of inhibiting the expression and activity of matrix metalloproteinases (MMPs) involved in collagen decomposition in the dermis. The culture broth of neural stem cells according to the present invention, which comprises, as active ingredients, high concentrations of TIMP-1 and TIMP-2 and low concentrations of various MMPs, restores the synthesis of collagen and elastin by suppressing the expression and activity of MMPs inhibiting collagen formation, and thus is useful as a composition for reducing skin wrinkles or increasing skin elasticity.

IPC Classes  ?

• A61K 8/98 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution of animal origin
• A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
• A61K 8/04 - DispersionsEmulsions
• A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
• A61K 8/66 - Enzymes
• A61Q 1/12 - Face or body powders, e.g. for grooming, adorning or absorbing
• A61Q 19/00 - Preparations for care of the skin
• A61Q 19/08 - Anti-ageing preparations
• A61Q 19/10 - Washing or bathing preparations

Abstract

Provided are a quantization method and a quantization apparatus for an artificial neural network. The quantization method for the artificial neural network may include estimating sample scale factors of first sample parameters that are part of first parameters within the artificial neural network, determining a prediction scale factor based on the sample scale factors, and quantizing first parameters based on the prediction scale factor.

IPC Classes  ?

• G06N 3/0495 - Quantised networksSparse networksCompressed networks

Abstract

The present invention relates to a method for manufacturing a water treatment separation membrane, the method comprising: a solution preparation step for preparing a modification solution; and a maintenance step in which a film form prepared by casting a polymer resin-containing polymer solution is maintained in the modification solution for one hour to manufacture a water treatment separation membrane, wherein the modification solution contains a base solvent, a pyrogallol compound containing a pyrogallol functional group, and a naturally derived amine material.

IPC Classes  ?

• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 65/08 - Prevention of membrane fouling or of concentration polarisation
• B01D 71/06 - Organic material
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis

Abstract

The present invention provides a linker having a net or cage structure, the structure of which is modified by a biomarker operating under a biphasic system consisting of a water layer and an oil layer. The linker is structurally modified in the presence of a biomarker to release a phase-shift probe contained therein, and the released phase-shift probe can be detected in the oil layer. In detection of the biomarker under the biphasic system using the linker of the present invention, the recognition of a target and the detection of a signal by the recognition are separated into the water layer and the oil layer, and thus the target can be detected with high accuracy. In addition, the system of the present invention does not require pretreatment of a sample, and thus can rapidly and accurately detect a quantitative biomarker with high sensitivity without expensive equipment and expertise required for pretreatment of a clinical specimen.

IPC Classes  ?

• C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
• G01N 21/84 - Systems specially adapted for particular applications

Abstract

The present invention relates to an intravenous fluid stand that can be connected to an escalator, the intravenous fluid stand comprising: a body extending in the up-down direction; wheels provided at the bottom of the body; and a coupling mechanism coupled to the body, wherein the coupling mechanism includes: a clamp formed near one side and detachably connected to a handrail of the escalator; and a connection assembly formed on the other side and connecting the intravenous fluid stand and the clamp. The clamp is coupled to the handrail during the course of loading the intravenous fluid stand onto the escalator, and is decoupled during the course of unloading the intravenous fluid stand from the escalator. The intravenous fluid stand is coupled to the handrail of the escalator such that the body of the intravenous fluid stand moves along with the handrail while at least a portion of the wheels are positioned on a footplate, and thus the intravenous fluid stand can be fixed on the escalator. The intravenous fluid stand is made to tilt rearward by a certain angle when coupled to the escalator. As a result, the wheels do not become caught when the intravenous fluid stand advances from the footplate to a landing plate while a patient is getting off the escalator, and the intravenous fluid stand is fixed when on the escalator, and thus stability may be improved.

IPC Classes  ?

• B66B 31/02 - Accessories for escalators, or moving walkways, e.g. for sterilising or cleaning for handrails
• A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor

Abstract

A catheter according to an embodiment is disclosed. In a catheter connected to an extracorporeal membrane oxygenation device, the catheter may comprise: a catheter body; and a wire which guides the intravascular insertion of the catheter body, wherein the catheter body may have, at an end portion thereof, an adjustable means for controlling a direction of outflow from the catheter body, and the adjustable means may be provided to form the end portion of the catheter body into a U-shape.

IPC Classes  ?

• A61M 25/00 - CathetersHollow probes
• A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
• A61M 60/38 - Blood oxygenation
• A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters

Abstract

The present invention relates to an information provision method for cancer diagnosis or prognosis prediction using microRNA containing 8-oxoguanine (o8G), a cancer therapeutic agent and a screening method thereof. By using microRNA in which guanine (G) at the 2nd or 7th nucleotide from the 5' end is modified to 8-oxoguanine, the progression pattern of cancer can be analyzed and controlled such that the microRNA can be effectively used for diagnosis, prognosis analysis, and treatment of cancer.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
• A61P 35/00 - Antineoplastic agents
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The present invention relates to an amylosome capable of saccharifying starch, and a method for treating waste food by using same. The amylosome capable of saccharifying starch, according to the present invention, can directly saccharify starch at a medium temperature in merely a single step, and can effectively decompose waste food contaminated with mold since, in addition to starch-degrading enzymes, mold-degrading enzymes are additionally introduced.

IPC Classes  ?

• C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• C07K 14/33 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Clostridium (G)
• C12N 9/26 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on alpha-1, 4-glucosidic bonds, e.g. hyaluronidase, invertase, amylase
• C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
• B09B 3/60 - Biochemical treatment, e.g. by using enzymes
• B09B 101/70 - Kitchen refuseFood waste

Abstract

A composite according to an embodiment of the present invention is characterized by including a defect-induced carbon body and a metal oxide coupled to the carbon body. The composite according to an embodiment of the present invention induces defects in the carbon body, thereby improving interfacial properties between the carbon body and the metal oxide, and has an increased contact area, thereby improving electrochemical properties of the composite.

IPC Classes  ?

• H01G 11/24 - Electrodes characterised by structural features of the materials making up or comprised in the electrodes, e.g. form, surface area or porosityElectrodes characterised by the structural features of powders or particles used therefor
• H01G 11/26 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features
• H01G 11/32 - Carbon-based
• H01G 11/46 - Metal oxides
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes

Abstract

Disclosed are an apparatus, a method, and a system for displaying a mixed reality-based ultrasound image. The method for displaying a mixed reality-based ultrasound image, according to an embodiment of the present invention, may comprise the steps of: obtaining an ultrasound image captured by an ultrasound device and positioning information about a probe of the ultrasound device; generating, on the basis of color information about the ultrasound image, a composite image in which transparencies of a target region and a background region included in the ultrasound image are adjusted to be distinguished from each other; and outputting the composite image according to an output position determined by using the positioning information.

IPC Classes  ?

• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

Abstract

The present invention relates to a composition for preventing or treating Alzheimer's disease, comprising a phospholipase C (PLC) activator as an active ingredient. A composition comprising the PLC activator of the present invention as an active ingredient restores the S-eCB mobilization suppressed by AβO, recovers the synaptic plasticity impaired by AβO, and not only recovers PLCβ1 protein levels to normal levels in AβO-treated mouse hippocampal slices and 5XFAD mouse hippocampal slices in the chronic stage of AD, but also recovers contextual fear memory impairment in AD mice, and thus is expected to be usefully used for preventing or treating Alzheimer's disease.

IPC Classes  ?

• A61K 31/18 - Sulfonamides
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The present invention relates to a separator membrane having a hierarchical structure, a production method therefor and a xylene separation method using same, and to: a separator membrane having a hierarchical structure comprising mesopores, the separator membrane having mesopores introduced inside a microporous zeolite separator membrane, thereby being thin, having less defects and exhibiting high xylene permeation and separation performance; a production method therefor; and a xylene separation method using same.

IPC Classes  ?

• B01D 71/02 - Inorganic material
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
• B01D 69/10 - Supported membranesMembrane supports

Abstract

There is provided a tag device including a first sensor, a second sensor, a pre-processor and a neural network processor. The pre-processor generates first position data of the tag device based on time information sensed by at least one of a third sensor included in each of the one or more anchor devices and the first sensor of the tag device, generates second position data based on first speed data of the tag device sensed by the second sensor and the first position data, and generates an image based on a path of movement of the tag device based on the second position data in an operation period, and the neural network processor classifies the image into one of a plurality of movements by using a trained neural network model.

IPC Classes  ?

• G01C 21/14 - NavigationNavigational instruments not provided for in groups by using measurement of speed or acceleration executed aboard the object being navigatedDead reckoning by recording the course traversed by the object
• G01P 13/00 - Indicating or recording presence or absence of movementIndicating or recording of direction of movement
• G06T 7/277 - Analysis of motion involving stochastic approaches, e.g. using Kalman filters

Abstract

The present invention relates to a device for maintaining vertebral body spacing and protecting the spinal cord. The device for maintaining vertebral body spacing and protecting the spinal cord, according to an embodiment of the present invention, comprises: a first body extending in the longitudinal direction; and a second body extending in the longitudinal direction, wherein the first body and the second body mutually approach to be coupled to each other, and are provided to form an internal space extending in the longitudinal direction therebetween and accommodate the spinal cord in the internal space, the first body includes: a first sleeve extending in the longitudinal direction; a first support portion extending forward from opposite sides in the longitudinal direction of the first sleeve; and a first accommodation portion extending in the longitudinal direction from the rear side of the first sleeve, the second body includes: a second sleeve extending in the longitudinal direction; a second support portion extending forward from opposite sides in the longitudinal direction of the second sleeve; and a second accommodation portion extending in the longitudinal direction from the rear side of the second sleeve, and the first support portion and the second support portion may be inserted between separated vertebral bodies.

IPC Classes  ?

• A61B 17/70 - Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant

Abstract

Disclosed is a method for manufacturing a photovoltaic module including forming a solar cell assembly by connecting a plurality of solar cells in an alignment direction in series, forming a plurality of solar cell units by cutting the solar cell assembly along a cutting line in a direction being different from the alignment direction, and disposing the plurality of solar cell units in an encapsulation member such that angles defined by a height direction of the encapsulation member and upper surfaces of the solar cell units are 30 degrees to 90 degrees.

IPC Classes  ?

• H01L 31/05 - Electrical interconnection means between PV cells inside the PV module, e.g. series connection of PV cells
• H01L 31/048 - Encapsulation of modules
• H01L 31/18 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof

Abstract

Provided are a base editor, specifically, a base editor in the form of a ribonucleoprotein (RNP) complex, and uses in gene correction in vivo using the same. When using the base editor in the form of an RNP complex of the present disclosure, target genes can be effectively corrected by reducing off-target effects.

IPC Classes  ?

• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• C12N 9/22 - Ribonucleases
• C12N 9/78 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• C12N 15/90 - Stable introduction of foreign DNA into chromosome

Abstract

According to various embodiments, a server providing an advertisement contract mediation platform may: acquire product feature information on the basis of at least one piece of content on a specific product acquired from a first external device; acquire a celebrity image of a specific celebrity among one or more celebrity images acquired from a second external device; acquire awareness information about the specific celebrity; acquire an advertisement image on the basis of the celebrity image, the product feature information, and the awareness information, the advertise image being an image in which the product feature information and the awareness information are overlapped with at least a partial area of the celebrity image; in response to the advertisement information including the advertisement image being transmitted to the second external device, acquire first result data indicating whether an advertisement contract is approved; and transmit contract information indicating the execution of the advertisement contract and acquired on the basis of the first result data to at least one of the first external device or the second external device so as to be output. Various other embodiments understood through the specification are possible.

IPC Classes  ?

• G06Q 30/02 - MarketingPrice estimation or determinationFundraising
• G06Q 30/06 - Buying, selling or leasing transactions
• G06N 20/00 - Machine learning

Abstract

An autofluorescence imaging device, according to one embodiment of the present disclosure, comprises: a light source for illuminating an examined eye through a preset optical path; an image sensor for imaging the examined eye of which at least a portion is emitting autofluorescence by the illumination from the light source; and a filter disposed between the image sensor and the examined eye, wherein the filter may comprise a plurality of portions each having mutually different light transmittances.

IPC Classes  ?

• A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes

Abstract

The present invention relates to an ultrasonic transducer position setting device, an ultrasonic transducer position setting program, and a method for implementing ultrasonic transducer position setting artificial intelligence. The ultrasonic transducer position setting device includes: an input/output unit for allowing a user to input data, and outputting the data in a form that is recognizable by the user; a memory for storing an ultrasonic transducer position setting program; and a control unit for executing the ultrasonic transducer position setting program to derive result data according to the data input through the input/output unit, wherein, when a focal point position of ultrasound, which is set to a region where a brain is positioned inside a skull in a living body, is input, the control unit outputs position data of an ultrasonic transducer, which allows the ultrasound to be applied to the input focal point position of the ultrasound.

IPC Classes  ?

• A61N 7/00 - Ultrasound therapy
• G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices

Abstract

The present invention provides a composition for preventing or treating muscular dystrophy, the composition comprising Zaltoprofen as an active ingredient. The composition according to the present invention increases the expression of utrophin, reduces the expression of myostatin, MAFbx, and MuRF1, and can inhibit muscle loss, increase muscle, and improve muscle function by inducing muscle differentiation and increasing the diameter of myotubes. Thus, the composition is expected to be used in various ways as medicines, quasi-medicines, fragrance materials, functional biomaterials, and functional food materials for alleviating, preventing, or treating muscular dystrophy.

IPC Classes  ?

• A61K 31/38 - Heterocyclic compounds having sulfur as a ring hetero atom
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system

Abstract

The present invention relates to: a catalyst for depolymerization of a polycarbonate-based resin, comprising a compound represented by chemical formula 1; a method for preparing same; a method for decomposing a polycarbonate-based resin using same; and a method for recovering the catalyst for depolymerization of a polycarbonate-based resin.

IPC Classes  ?

• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
• B01J 31/04 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing carboxylic acids or their salts
• B01J 37/04 - Mixing
• B01J 38/48 - Liquid treating or treating in liquid phase, e.g. dissolved or suspended
• C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
• C07C 37/055 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by oxygen, e.g. ether group
• C07C 37/70 - SeparationPurificationStabilisationUse of additives by physical treatment
• C07C 39/16 - Bis(hydroxy phenyl)alkanesTris(hydroxy phenyl)alkanes

Abstract

A method for detecting an anomaly, which is performed by a computing device including one or more processors according to some embodiments of the present disclosure may include: collecting a CAN message generated in a controller area network (CAN); generating first traffic time interval data and first payload data based on the CAN message; obtaining a first latent vector generated by inputting the first traffic time interval data into a first neural network model; obtaining a second latent vector generated by inputting the first payload data into a second neural network model; generating merged data in which the first latent vector and the second latent vector are merged; and determining whether the CAN message is anomalous by inputting the merged data into a third neural network model.

IPC Classes  ?

• H04L 9/40 - Network security protocols
• G06N 3/0495 - Quantised networksSparse networksCompressed networks

Abstract

Disclosed is a decision feedback equalizer, which includes a summator that receives a gray code-based PAM-4 signal, a first bit signal, and a second bit signal, and outputs an input voltage obtained by adding a preset coefficient to a voltage level of the PAM-4 signal in response to the first bit signal and the second bit signal, and a decoder that receives the input voltage and first to third reference voltages of the PAM-4 signal and outputs the first bit signal and the second bit signal, and the decoder includes a first comparator that outputs the first bit signal by comparing a magnitude of the input voltage with a magnitude of the first reference voltage, and a second comparator that outputs the second bit signal by comparing charge-discharge intensities of the input voltage and the second and third reference voltages.

IPC Classes  ?

• H04L 25/03 - Shaping networks in transmitter or receiver, e.g. adaptive shaping networks

Abstract

43233).

IPC Classes  ?

• H03B 19/14 - Generation of oscillations by non-regenerative frequency multiplication or division of a signal from a separate source by means of discharge device or semiconductor device with more than two electrodes by means of a semiconductor device
• H03B 19/18 - Generation of oscillations by non-regenerative frequency multiplication or division of a signal from a separate source using uncontrolled rectifying devices, e.g. rectifying diodes or Schottky diodes and elements comprising distributed inductance and capacitance
• H01P 5/02 - Coupling devices of the waveguide type with invariable factor of coupling

Abstract

The present invention relates to a composition and a kit for diagnosing autism disorder. The composition, the kit, and a method for providing information according to the present invention can conveniently and effectively diagnose autism disorder in a small amount of blood by using multiple biomarkers in which proteins and metabolites have been combined in order to diagnose autism disorder.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

The present invention relates to a cerebral blood flow measuring device comprising: a flexible base configured to be transformed correspondingly to the shape of a head in close contact therewith; a plurality of light irradiation units provided on an installation surface, facing the head, of the flexible base; a plurality of light detection units provided on the installation surface; and an expansion unit configured to transform the flexible base. The cerebral blood flow measuring device using near-infrared spectroscopy according to the present invention can improve measurement accuracy by actively adjusting the pressure of the flexible base to thus bring the light irradiation units and the light detection units into close contact with each other according to the shape and size of the head.

IPC Classes  ?

• A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

Disclosed is a device and method of training a deep learning model capable of using multi-level and multi-length latent vectors. The method of training the deep learning model is performed by a computing device including at least a processor and includes generating a basic model; and training the basic model, and the basic model includes a plurality of layer blocks each including at least one layer, and the layer blocks include first layer blocks configured to receive input data or output of a previous layer block to compress or encode data, or to output a latent vector corresponding to the input data and second layer blocks configured to receive the latent vector and the output of the previous layer block to restore or decode the data, or to derive inference results corresponding to the input data.

IPC Classes  ?

• G06N 3/08 - Learning methods
• G06N 3/0455 - Auto-encoder networksEncoder-decoder networks

Abstract

The present disclosure relates to a method of determining satellite orbital positions and routing for a Low Earth Orbit (LEO) satellite network, and the method calculates a communication throughput in each of a link between the transmitting base station and a satellite deployed on the first orbit, a link between satellites deployed on the first and second orbits, and a link between a satellite deployed on the second orbit and the receiving base station, and calculating a communication throughput in an entire link between the transmitting base station and the receiving base station on the basis of the communication throughput in each link, determines satellite orbital position variables and routing variables for maximizing the communication throughput in the entire link, and determines deployment of satellites on the first and second orbits on the basis of the satellite orbit position variables and routing variables.

IPC Classes  ?

• H04B 7/185 - Space-based or airborne stations

Abstract

The method for predicting Alzheimer's disease-related biomarkers according to the present disclosure involves a method executed by one or more processors of a computing device. The method comprises collecting medical images of a subject, preprocessing the collected medical images to generate training data, training a biomarker prediction model using the generated training data and the subject's demographic and clinical information, where the training includes assigning weights to the training data, and predicting Alzheimer's disease-related biomarkers for a patient using the trained biomarker prediction model.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
• G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Abstract

A resource block scheduling method and an electronic device performing the method are disclosed. An electronic device according to various embodiments may comprise: at least one processor, comprising processing circuitry, and a memory electrically connected to at least one processor and storing instructions executable by the processor, wherein at least one processor, individually and/or collectively, is configured to execute the instructions and to: A resource block scheduling method and an electronic device performing the method are disclosed. An electronic device according to various embodiments may comprise: at least one processor, comprising processing circuitry, and a memory electrically connected to at least one processor and storing instructions executable by the processor, wherein at least one processor, individually and/or collectively, is configured to execute the instructions and to: based on channel quality information indexes (CQIs) relating to a plurality of terminals, acquire achievable rates based on resource blocks being allocated to the plurality of terminals; and input the achievable rates to a trained neural network model to output a schedule for allocation of the resource blocks to the plurality of terminals, and the neural network model is configured to be trained to collect the training CQIs relating to the plurality of terminals, acquire, based on the training CQIs, training achievable rates based on the resource blocks being allocated to the plurality of terminals, and output the schedule, in which the sum of the rates for the plurality of terminals is maximized and fairness indexes for the plurality of terminals satisfy a configured fairness condition, using the input training achievable rates.

IPC Classes  ?

• H04W 72/121 - Wireless traffic scheduling for groups of terminals or users
• H04W 72/542 - Allocation or scheduling criteria for wireless resources based on quality criteria using measured or perceived quality

Abstract

The present invention relates to a method for efficiently preparing rucaparib for a PET image. More specifically, the present invention relates to an improved preparation method for synthesizing [18F]-rucaparib in excellent yield by means of a pathway for synthesizing a pinacol boronate derivative, which is a key intermediate, by using, as a starting material, a 2-iodoaniline derivative prepared by a novel synthesis method.

IPC Classes  ?

• C07D 487/04 - Ortho-condensed systems
• C07B 59/00 - Introduction of isotopes of elements into organic compounds
• C07D 209/18 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
• A61K 51/04 - Organic compounds

Abstract

The present invention relates to a method for efficiently preparing 2-amino-4-fluoro-6- methoxycarbonylcinnamonitrile. More specifically, the present invention relates to an improved preparation method for synthesizing 2-amino-4-fluoro-6-methoxycarbonylcinnamonitrile, which is a key intermediate in preparing rucaparib with excellent yield through a novel synthesis route using, as a starting material, alkyl 5-fluoro-2-methyl-3-nitrobenzoate rather than a conventional 2-iodoaniline derivative.

IPC Classes  ?

• C07C 253/30 - Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
• C07C 255/42 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
• C07C 255/64 - Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to oxygen atoms
• C07C 255/41 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups

Abstract

Disclosed is an electricity generation device. The present invention provides an electricity generation device, including: a first electrolyte, selectively permeable membrane, and second electrolyte in a chamber thereof, wherein each of the first electrolyte and the second electrolyte includes at least two types of ions, and at least three types of ions are included in the first electrolyte and the second electrolyte, the selectively permeable membrane selectively permeates at least one type of ions among the at least three types of ions to cause Donnan effect between the first electrolyte and the second electrolyte.

IPC Classes  ?

• H01M 8/22 - Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elementsFuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen
• H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells

Abstract

Disclosed is a privacy-preserving electrocardiogram (ECG) data collecting method for arrhythmia classification. The privacy-preserving ECG data collecting method is performed by a computing device including at least a processor and includes training a feature extraction model, a personal identification model, and an arrhythmia classification model using learning data that includes ECG data with a predetermined length; and training a noise model, and the feature extraction model receives the ECG data as input and outputs ECG features, the personal identification model receives the ECG features as input and identifies an individual corresponding to the ECG features, the arrhythmia classification model receives the ECG features as input and classifies arrhythmia corresponding to the ECG features, and the noise model generates noise with the same length as that of the ECG features.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• A61B 5/349 - Detecting specific parameters of the electrocardiograph cycle
• G06N 3/045 - Combinations of networks
• G06N 3/084 - Backpropagation, e.g. using gradient descent

Abstract

Disclosed is a field programmable gate array device including a plurality of lookup tables each storing data. Each lookup table includes a cell array including cells connected to a plurality of word lines, a drive circuit connected to the cell array through the plurality of word lines, and a peripheral circuit connected to the cell array through a plurality of bit lines and source lines, and configured to control the drive circuit. The drive circuit drives a first word line among the word lines based on first input signals. The peripheral circuit performs a data write operation on a first cell connected to the first word line, based on a first command and a second input signal, and performs a data read operation on the first cell connected to the first word line, based on a second command and the second input signal.

IPC Classes  ?

• G06F 3/06 - Digital input from, or digital output to, record carriers
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• H03K 19/17728 - Reconfigurable logic blocks, e.g. lookup tables

Abstract

The present disclosure relates to a novel human antibody or an antigen-binding fragment thereof that recognizes the SMO (smoothened) protein as an antigen and binds specifically thereto. The antibody of the present disclosure binds specifically to the SMO protein, which is directly involved in major cancer progression processes such as proliferation, migration, invasion and metastasis of cancer cells, and blocks the progression those processes. Therefore, it can be usefully used as a therapeutic agent for various cancers such as colon cancer, etc., resistant cancer, metastatic cancer, or recurrent cancer.

IPC Classes  ?

• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 35/00 - Antineoplastic agents
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

Abstract

The present invention relates to a building drawing design device and method, the building drawing design method comprising the steps of: acquiring basic data for generating a building drawing; using a trained learning model to acquire a generation drawing corresponding to the basic data; and performing post-processing on the generation drawing so as to acquire a resulting drawing corresponding to the basic data, wherein the trained learning model can be acquired by the steps of: acquiring at least one reference drawing corresponding to at least one original drawing; removing some or all of the space of the at least one reference drawing so as to generate at least one input drawing corresponding to the at least one reference drawing; and training the learning model by using the at least one reference drawing and the at least one input drawing.

IPC Classes  ?

• G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
• G06F 30/13 - Architectural design, e.g. computer-aided architectural design [CAAD] related to design of buildings, bridges, landscapes, production plants or roads
• G06V 30/422 - Technical drawingsGeographical maps
• G06V 10/24 - Aligning, centring, orientation detection or correction of the image
• G06F 16/11 - File system administration, e.g. details of archiving or snapshots
• G06F 119/10 - Noise analysis or noise optimisation

Abstract

Disclosed is a device and method for lightweight container packet processing in an Internet of things (IoT) environment. A packet processing method is performed by a server that provides a container environment to an IoT device and includes receiving a packet from a container assigned to the IoT device; determining a packet processing path to process the packet; processing the packet according to the determined packet processing path; and transmitting the packet of which packet processing is completed to an external network.

IPC Classes  ?

• H04L 45/745 - Address table lookupAddress filtering

Abstract

The present invention relates to miRNA-4449, which is a biomarker that can be used to diagnose nonalcoholic steatohepatitis, and at least one miRNA selected from the group consisting of miRNA-15, miRNA-21, miRNA-29, miRNA-126, miRNA-151, miRNA-183, and miRNA-192. The prognosis of nonalcoholic steatohepatitis among nonalcoholic fatty liver diseases is poor unlike simple steatosis. According to the present invention, the level of the miRNA can be measured in the serum of a patient to provide an accurate diagnostic result of nonalcoholic steatohepatitis, thus making it possible to eliminate side effects caused by conventional invasive test methods, and enabling early diagnosis and appropriate treatment of steatohepatitis in a simple and economical manner.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

Disclosed is an implantable monitoring and treatment device. The implantable monitoring and treatment device comprises: a jacket unit which surrounds an organ in the body and is made of an elastic material so as to deform according to the expansion and contraction of the organ; and a biometric signal measurement unit which is provided in the jacket unit and measures biometric signals from the organ. The jacket unit includes: a first pad which has a prescribed area and is in close contact with one region of the organ; a second pad which has a prescribed area and is in close contact with another region of the organ; and at least one fastening string connecting the first pad and the second pad.

IPC Classes  ?

• A61B 5/251 - Means for maintaining electrode contact with the body
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons
• A61B 5/283 - Invasive
• A61B 5/296 - Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]

Abstract

Disclosed are a signal measurement device for measuring signals of a plurality of organoids, and a control method for controlling the signal measurement device. The signal measurement device may comprise: a well plate in which chambers accommodating organoids are disposed; a probe array including probes in which electrodes are disposed; a cover in which the probe array is disposed; a gap adjustment unit for adjusting a gap between the well plate and the probe array; and a control unit for controlling the gap adjustment unit to adjust the gap between the well plate and the probe array on the basis of changes in an electrical signal measured by the electrodes.

IPC Classes  ?

• G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
• G01N 33/483 - Physical analysis of biological material
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• C12N 5/079 - Neural cells
• G01N 27/327 - Biochemical electrodes
• G01B 7/16 - Measuring arrangements characterised by the use of electric or magnetic techniques for measuring the deformation in a solid, e.g. by resistance strain gauge

Abstract

A screening device for analyzing multiple organoids is disclosed. The screening device comprises: a microfluidic chip in which one or more microfluidic channels through which a drug flows are arranged; a well plate in which a plurality of chambers accommodating organoids are arranged; and a probe array in which probes inserted into the organoids so as to measure a signal in each organoid are arranged in an array form, wherein a first microfluidic channel among the one or more microfluidic channels is arranged to be adjacent to a first chamber array in which some of the chambers are arranged in an array form, and the drug flowing in the first microfluidic channel can be delivered to each organoid accommodated in the first chamber array through porous films having different porosities.

IPC Classes  ?

• G01N 33/483 - Physical analysis of biological material
• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• C12N 5/079 - Neural cells

Abstract

Provided are Fc variants having improved half-life by binding to and unbinding from FcRn in a pH-dependent manner, which have improved capacity to selectively bind to Fcγ receptors. The human Fc domain variants have lower capacity to bind to immune-inhibiting receptor FcγRIIb and have higher capacity to bind to immune activating receptor FcγRIIIa (increased A/I ratio) than a wild-type human antibody Fc domain and conventional antibodies approved as antibody therapeutic agents, thereby having remarkably improved ADCC induction ability and having maximized half-life in blood in which excellent pH-selective FcRn binding and unbinding capacity is exhibited, and thus bind to numerous peptide drug therapeutics having a low half-life and retention time in the body to enable the peptide drug therapeutics to have an increased blood half-life and exhibit long-term drug efficacy, and can maximize the immune mechanism of therapeutic protein drugs to be effectively used as an improved antibody drug.

IPC Classes  ?

• C07K 16/32 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products from oncogenes
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment

Abstract

Disclosed herein are a method and a biomarker for predicting efficacy and prognosis of or resistance to an immunotherapy. The use of the biomarkers (TCTP, EGFR, AKT, MCL1, and/or CXCL10) of the present disclosure allows the prediction of resistance to or prognosis of a cancer immunotherapeutic agent and the selection of a therapy guaranteeing therapeutic benefit, thereby finding advantageous applications in treating cancers or tumors resistant to cancer immunotherapeutic agents.

IPC Classes  ?

• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

The present invention relates to a chromene-benzimidazole derivative or a pharmaceutically acceptable salt thereof, and a composition containing the derivative as an active ingredient for preventing or treating cancer. The chromene-benzimidazole derivative of the present invention is activated in cancer cells to inhibit tubulin polymerization and suppress the C-terminal domain of Hsp90, thereby blocking the cell cycle of cancer cells, inducing apoptosis, and inhibiting the activity of oncoproteins, and thus can be used as a novel dual-target anticancer drug for preventing or treating cancer, preferably for preventing or treating triple-negative breast cancer.

IPC Classes  ?

• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
• A61P 35/00 - Antineoplastic agents

Abstract

A semiconductor device includes a capacitor including a first electrode, a second electrode, and a dielectric layer between the first electrode and the second electrode, where at least one of the first electrode and the second electrode includes a nanolaminate electrode, the nanolaminate electrode includes a plurality of first material layers and a plurality of second material layers, the plurality of first material layers and the plurality of second material layers being alternately arranged, the plurality of first material layers includes indium oxide (In2O3), the plurality of second material layers includes molybdenum oxide (MoOx), each of the plurality of first material layers has a thickness between about 2 angstroms to about 6 angstroms, and each of the plurality of second material layers includes a monolayer of molybdenum oxide.

IPC Classes  ?

• H01G 4/06 - Solid dielectrics

Abstract

Disclosed is a qubit system based on magnetic resonance, according to some embodiments of the present disclosure. The qubit system may comprise: a magnet having a space provided on the inside thereof; a qubit sample which is disposed in the space provided on the inside of the magnet and contains a material capable of quantum state transition; a gradient coil which is disposed on the outside of the qubit sample to correspond to the qubit sample on the inside of the magnet and generates a gradient magnetic field in the space on the inside of the magnet, which has the qubit sample contained therein; an RF transmitting coil part disposed between the qubit sample and the gradient coil on the inside of the magnet, to apply radio frequency (RF) pulses to the qubit sample and control a quantum state of the qubit sample; and an RF receiving coil disposed on the inside of the magnet to receive RF signals emitted from the qubit sample due to the applied RF pulses.

IPC Classes  ?

• G06N 10/40 - Physical realisations or architectures of quantum processors or components for manipulating qubits, e.g. qubit coupling or qubit control
• G06N 10/20 - Models of quantum computing, e.g. quantum circuits or universal quantum computers
• G06N 20/10 - Machine learning using kernel methods, e.g. support vector machines [SVM]
• B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic

Abstract

A method of reconstructing a downlink (DL) channel by a base station in a multiple-input-multiple-output (MIMO) communication system includes: estimating UL channel information on the basis of an uplink (UL) pilot signal received from a user equipment; extracting at least one key parameter among common parameters of the UL channel and the DL channel from the estimated UL channel information; estimating DL channel information using the UL channel information and the at least one key parameter; and reconstructing the DL channel by correcting an error between the estimated DL channel information and actual DL channel information.

IPC Classes  ?

• H04B 7/0413 - MIMO systems
• H04L 5/00 - Arrangements affording multiple use of the transmission path
• H04W 72/1273 - Mapping of traffic onto schedule, e.g. scheduled allocation or multiplexing of flows of downlink data flows
• H04W 72/21 - Control channels or signalling for resource management in the uplink direction of a wireless link, i.e. towards the network
• H04W 72/54 - Allocation or scheduling criteria for wireless resources based on quality criteria

Abstract

The present invention provides a composition for freezing control, a composition for freezing a cell, and a composition for freezing a food, which include a compound in which 2 to 5 amino acids, for example, 2, 3, 4, or 5 amino acids are connected to fluorenylmethyloxycarbony (Fmoc) through peptide bonding.

IPC Classes  ?

• A01N 1/02 - Preservation of living parts
• A23L 3/3526 - Organic compounds containing nitrogen
• A23L 3/3535 - Organic compounds containing sulfur

Abstract

An intestinal content delivery device for an intestinal fistula patient according to one embodiment of the present invention comprises: a nutrient delivery tube having a nutrient delivery passage inserted into an intestinal fistula of a user to deliver nutrients between an upper intestinal fistula and a lower intestinal fistula; and a nutrient supply tube coupled to one side of the nutrient delivery tube so as to communicate with the nutrient delivery passage. The nutrient delivery tube may comprise: an upper intestinal fistula insertion tube that is provided to be insertable into the upper intestinal fistula, has a first nutrient delivery passage, and has at least one first through-hole formed at one end thereof so that nutrients present in the upper intestinal fistula can flow therethough; and a lower intestinal fistula insertion tube that is provided to be insertable into the lower intestinal fistula, has a second nutrient delivery passage which communicates with the first nutrient delivery passage, and has at least one second through-hole formed at one end thereof so that nutrients delivered from the upper intestinal fistula through the first through-hole and the first nutrient delivery passage can be delivered to the lower intestinal fistula.

IPC Classes  ?

• A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts

Abstract

The present disclosure relates to a TIS-L targeting antisense oligonucleotide that inhibits the viral replication of SARS-COV-2 and antiviral use thereof. Since the TIS-L targeting antisense oligonucleotide according to the present disclosure has a simple structure, it is easy to mass produce, and as it exhibits antiviral efficacy of 90% or more even at low doses against the original strain and various modified strains of the virus, it can be advantageously utilized in the development of COVID-19 treatment.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61P 31/14 - Antivirals for RNA viruses

Abstract

Disclosed is a Light-Emitting Device-Thin Film Transistor (LED-TFT) integration structure, comprising a substrate comprising a light emitting area and a driving area; a metal reflective film formed on the substrate; a buffer layer formed on the metal reflective film; LED disposed in the light emitting area; a protective layer formed on the LED; a thin film transistor disposed in the driving area and configured to drive the LED; and an ohmic contact metal for electrically connecting a cathode of the LED with the metal reflective film, wherein the LED and the thin film transistor are integrally formed on the substrate.

IPC Classes  ?

• H01L 25/16 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices the devices being of types provided for in two or more different subclasses of , , , , or , e.g. forming hybrid circuits
• H01L 27/12 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being other than a semiconductor body, e.g. an insulating body
• H01L 33/12 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a stress relaxation structure, e.g. buffer layer
• H01L 33/46 - Reflective coating, e.g. dielectric Bragg reflector
• H01L 33/62 - Arrangements for conducting electric current to or from the semiconductor body, e.g. leadframe, wire-bond or solder balls

Abstract

The present invention relates to a POMC-specific antibody and use thereof, and use of Marchf6 for treating metabolic diseases. It has been found that the cytosolic accumulation of POMC, which is an appetite-regulating hormone precursor protein, induces ER stress and ferroptosis, and Marchf6 degrades POMC by directly binding thereto, causing the translocation of POMC into ER. Also, it has been confirmed that a produced POMC-specific antibody can specifically detect POMC accumulated in the cytosol of POMC neurons. Therefore, these can be used for the diagnosis and treatment of diseases associated with POMC accumulation or Marchf6 dysfunction. It has also been found that ER stress and ferroptosis caused by accumulation of POMC in the cytosol are regulated. In particular, it was confirmed in vivo that Marchf6 deficiency in POMC neurons causes metabolic disorders. Therefore, Marchf6 can be effectively used for the prevention or treatment of metabolic diseases, including obesity.

IPC Classes  ?

• C07K 14/665 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
• C07K 16/26 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones
• A61P 3/00 - Drugs for disorders of the metabolism
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A23L 33/17 - Amino acids, peptides or proteins
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

Disclosed is a method and apparatus for determining diagnosis result data by using a thermal image. A method for determining diagnosis result data may comprise the steps of: acquiring a first thermal image indicating a temperature change of skin, to which thermal stimulation has been applied, over time; acquiring a second thermal image indicating a temperature change of skin, to which cold stimulation has been applied, over time; extracting a temperature restoration feature of the skin from each of the first thermal image and the second thermal image; and determining diagnosis result data related to the skin on the basis of the temperature restoration feature extracted from the first thermal image and the temperature restoration feature extracted from the second thermal image.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G06T 7/00 - Image analysis
• G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
• G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
• G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment

Abstract

There is provided with a blockchain-based evidence data notarization system comprising a user terminal for transmitting the evidence data in accordance with a notarization request; a notary server for transmitting the generated hash value to the user terminal and a notary terminal, respectively; and a blockchain server for receiving a signature written in the hash value from the user terminal and the notary terminal, respectively and generating a smart contract block.

IPC Classes  ?

• G06Q 50/18 - Legal services
• H04L 9/00 - Arrangements for secret or secure communicationsNetwork security protocols

Abstract

The present invention can provide a method for preparing a sulfide-based solid electrolyte in a short time using a solvothermal synthesis method. In addition, the present invention may provide a sulfide-based solid electrolyte prepared by the method. In addition, the present invention may provide an electrode for an all-solid-state battery including the sulfide-based solid electrolyte.

IPC Classes  ?

• H01M 10/0562 - Solid materials
• C01G 17/00 - Compounds of germanium
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

Abstract

The present invention relates to a zwitterionic polymer-based aqueous electrolyte having a high potential stability window through control of a hydration layer, and a manufacturing method thereof. According to one embodiment, a zwitterionic polymer-based aqueous electrolyte having a high potential stability window through control of a hydration layer may be provided, the zwitterionic polymer-based aqueous electrolyte including a polymer hydrogel having a three-dimensional network structure composed of: a zwitterionic polymer structure derived from an ionic polymer monomer and polymerized and crosslinked through a crosslinker and an initiator; and a hydration layer formed on the surface of the zwitterionic polymer structure.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/36 - Accumulators not provided for in groups
• C08F 230/02 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
• C08F 222/10 - Esters
• C08F 2/44 - Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
• C08K 3/105 - Compounds containing metals of Groups 1 to 3 or of Groups 11 to 13 of the Periodic Table

Abstract

The present invention relates to an electrolyte using a high-dielectric-constant zwitterionic material, and a preparation method therefor. According to an embodiment, the provided electrolyte using a high-dielectric-constant zwitterionic material, which is for a secondary battery using a metal anode material as an anode, comprises an electrolyte mixture composed of: an organic electrolyte including an organic solvent and a metal salt; and a zwitterionic compound having a weight average molecular weight that satisfies a range of 100-60,000 g/mol and having a zwitterion.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/134 - Electrodes based on metals, Si or alloys
• C08F 220/06 - Acrylic acidMethacrylic acidMetal salts or ammonium salts thereof
• C08F 222/10 - Esters
• C08F 2/44 - Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
• C08K 5/11 - EstersEther-esters of acyclic polycarboxylic acids

Abstract

The present disclosure provides a state estimation apparatus of estimating a current state of an object based on state information and observation information for dynamically replicating the object, the state estimation apparatus including an input unit that receives the observation information, and a current state estimation unit that generates current state estimation information through the observation information, wherein the current state estimation unit includes a prediction information generation unit that generates state prediction information through inputting past state estimation information obtained by delaying the current state estimation information by one time unit into a previously prepared state prediction model, and a prediction information correction unit that calculates a Kalman gain matrix associated with a degree of correction of the state prediction information through artificial neural network(s), and corrects the state prediction information through the observation information and the Kalman gain matrix to generate the current state estimation information.

IPC Classes  ?

• G01S 7/41 - Details of systems according to groups , , of systems according to group using analysis of echo signal for target characterisationTarget signatureTarget cross-section
• G01S 13/06 - Systems determining position data of a target

Abstract

Provided with a blockchain-based shared asset trading system for tokenizing and trading a shared asset comprising a plurality of sharer terminals, provided on a sharer side, for transmitting an original warranty containing the appraisal result of the shared asset and transmitting a warranty in which the sharer's signature has been entered to the original warranty; a blockchain network for receiving and storing the original warranty in a smart contract block, issuing a token based on the smart contract block and generating an electronic wallet in which the token is stored; and an electronic wallet management server for receiving the warranty in which the signature has been entered from the plurality of sharer terminals and transmitting a transaction including the warranty in which the signature has been entered to the original warranty.

IPC Classes  ?

• G06Q 20/38 - Payment protocolsDetails thereof
• G06Q 20/36 - Payment architectures, schemes or protocols characterised by the use of specific devices using electronic wallets or electronic money safes
• G06Q 30/012 - Providing warranty services
• G06Q 40/04 - Trading Exchange, e.g. stocks, commodities, derivatives or currency exchange
• G06Q 50/18 - Legal services

Abstract

Disclosed is a photovoltaic module including an encapsulation part, a plurality of solar cells disposed in the encapsulating part such that angles thereof with respect to a height direction of the encapsulation part is 30 degrees to 90 degrees, and impact absorption parts disposed between the plurality of solar cells in the encapsulation part.

IPC Classes  ?

• H01L 31/048 - Encapsulation of modules

Abstract

An embodiment of the present invention provides a processing-in-memory memory device comprising: a memory bank including a memory array for receiving a memory request from a memory controller, and a PIM engine for executing processing-in-memory according to the PIM instruction; and a processing-in-memory (PIM) control unit for controlling the processing-in-memory of the PIM engine by identifying a PIM instruction corresponding to the memory request, and storing addressing mode selection information for selecting one among an indirect address and a direct address according to the identified PIM instruction, wherein when the indirect address is used, the PIM control unit uses a register value of the processing-in-memory control unit as a base register value, reads an immediate value in the PIM instruction, a register value of the PIM engine, or an offset value of the memory bank, and generates an effective address for the processing-in-memory in an indirect addressing mode.

IPC Classes  ?

• G06F 9/30 - Arrangements for executing machine instructions, e.g. instruction decode