KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Choi, Jungkyu
Lee, Kwan Young
Hong, Sung-Won
Abrégé
The present invention relates to a separator membrane having a hierarchical structure, a production method therefor and a xylene separation method using same, and to: a separator membrane having a hierarchical structure comprising mesopores, the separator membrane having mesopores introduced inside a microporous zeolite separator membrane, thereby being thin, having less defects and exhibiting high xylene permeation and separation performance; a production method therefor; and a xylene separation method using same.
B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
B01D 69/10 - Membranes sur supportSupports pour membranes
2.
COMPOSITION FOR PREVENTING OR TREATING ALZHEIMER'S DISEASE COMPRISING PHOSPHOLIPASE C ACTIVATOR AS AN ACTIVE INGREDIENT
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kwag, Jeehyun
Lee, Jaedong
Abrégé
The present invention relates to a composition for preventing or treating Alzheimer's disease, comprising a phospholipase C (PLC) activator as an active ingredient. A composition comprising the PLC activator of the present invention as an active ingredient restores the S-eCB mobilization suppressed by AβO, recovers the synaptic plasticity impaired by AβO, and not only recovers PLCβ1 protein levels to normal levels in AβO-treated mouse hippocampal slices and 5XFAD mouse hippocampal slices in the chronic stage of AD, but also recovers contextual fear memory impairment in AD mice, and thus is expected to be usefully used for preventing or treating Alzheimer's disease.
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
3.
TAG DEVICE FOR RECOGNIZING MOTION, MOTION RECOGNIZER, AND METHOD OF OPERATING THE TAG DEVICE
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
Korea University Research And Business Foundation (République de Corée)
Inventeur(s)
Kim, Hyunsoon
Kim, Hwangnam
Kim, Jun
Suh, Seungchull
Yoo, Kyeonghyun
Lee, Dongjae
Abrégé
There is provided a tag device including a first sensor, a second sensor, a pre-processor and a neural network processor. The pre-processor generates first position data of the tag device based on time information sensed by at least one of a third sensor included in each of the one or more anchor devices and the first sensor of the tag device, generates second position data based on first speed data of the tag device sensed by the second sensor and the first position data, and generates an image based on a path of movement of the tag device based on the second position data in an operation period, and the neural network processor classifies the image into one of a plurality of movements by using a trained neural network model.
G01C 21/14 - NavigationInstruments de navigation non prévus dans les groupes en utilisant des mesures de la vitesse ou de l'accélération exécutées à bord de l'objet navigantNavigation à l'estime en enregistrant la route parcourue par l'objet
G01P 13/00 - Indication ou enregistrement de l'existence ou de l'absence d'un mouvementIndication ou enregistrement de la direction d'un mouvement
G06T 7/277 - Analyse du mouvement impliquant des approches stochastiques, p. ex. utilisant des filtres de Kalman
4.
DEVICE FOR MAINTAINING VERTEBRAL BODY SPACING AND PROTECTING SPINAL CORD
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
An, Sung-Jae
Abrégé
The present invention relates to a device for maintaining vertebral body spacing and protecting the spinal cord. The device for maintaining vertebral body spacing and protecting the spinal cord, according to an embodiment of the present invention, comprises: a first body extending in the longitudinal direction; and a second body extending in the longitudinal direction, wherein the first body and the second body mutually approach to be coupled to each other, and are provided to form an internal space extending in the longitudinal direction therebetween and accommodate the spinal cord in the internal space, the first body includes: a first sleeve extending in the longitudinal direction; a first support portion extending forward from opposite sides in the longitudinal direction of the first sleeve; and a first accommodation portion extending in the longitudinal direction from the rear side of the first sleeve, the second body includes: a second sleeve extending in the longitudinal direction; a second support portion extending forward from opposite sides in the longitudinal direction of the second sleeve; and a second accommodation portion extending in the longitudinal direction from the rear side of the second sleeve, and the first support portion and the second support portion may be inserted between separated vertebral bodies.
A61B 17/70 - Dispositifs de mise en position ou de stabilisation de la colonne vertébrale, p. ex. stabilisateurs comprenant un liquide de remplissage dans un implant
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jeong Hun
Woo, Jae-Sung
Bae, Sang Su
Abrégé
Provided are a base editor, specifically, a base editor in the form of a ribonucleoprotein (RNP) complex, and uses in gene correction in vivo using the same. When using the base editor in the form of an RNP complex of the present disclosure, target genes can be effectively corrected by reducing off-target effects.
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Donghwan
Kang, Yoonmook
Lee, Hae-Seok
Jun, Yongseok
Lee, Chanyong
Ko, Jongwon
Abrégé
Disclosed is a method for manufacturing a photovoltaic module including forming a solar cell assembly by connecting a plurality of solar cells in an alignment direction in series, forming a plurality of solar cell units by cutting the solar cell assembly along a cutting line in a direction being different from the alignment direction, and disposing the plurality of solar cell units in an encapsulation member such that angles defined by a height direction of the encapsulation member and upper surfaces of the solar cell units are 30 degrees to 90 degrees.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Janghyuk
Jang, Seungwon
Yu, Taejun
Abrégé
According to various embodiments, a server providing an advertisement contract mediation platform may: acquire product feature information on the basis of at least one piece of content on a specific product acquired from a first external device; acquire a celebrity image of a specific celebrity among one or more celebrity images acquired from a second external device; acquire awareness information about the specific celebrity; acquire an advertisement image on the basis of the celebrity image, the product feature information, and the awareness information, the advertise image being an image in which the product feature information and the awareness information are overlapped with at least a partial area of the celebrity image; in response to the advertisement information including the advertisement image being transmitted to the second external device, acquire first result data indicating whether an advertisement contract is approved; and transmit contract information indicating the execution of the advertisement contract and acquired on the basis of the first result data to at least one of the first external device or the second external device so as to be output. Various other embodiments understood through the specification are possible.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Eom, Young Sub
Kim, Seong Woo
Suh, Young Woo
Abrégé
An autofluorescence imaging device, according to one embodiment of the present disclosure, comprises: a light source for illuminating an examined eye through a preset optical path; an image sensor for imaging the examined eye of which at least a portion is emitting autofluorescence by the illumination from the light source; and a filter disposed between the image sensor and the examined eye, wherein the filter may comprise a plurality of portions each having mutually different light transmittances.
A61B 3/117 - Appareils pour l'examen optique des yeuxAppareils pour l'examen clinique des yeux du type à mesure objective, c.-à-d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner la chambre antérieure ou l'angle de la chambre antérieure, p. ex. gonioscopes
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Noh, Gun Woo
Yoon, Kyung Ho
Jang, Min Yeong
Choi, Min Wook
Abrégé
The present invention relates to an ultrasonic transducer position setting device, an ultrasonic transducer position setting program, and a method for implementing ultrasonic transducer position setting artificial intelligence. The ultrasonic transducer position setting device includes: an input/output unit for allowing a user to input data, and outputting the data in a form that is recognizable by the user; a memory for storing an ultrasonic transducer position setting program; and a control unit for executing the ultrasonic transducer position setting program to derive result data according to the data input through the input/output unit, wherein, when a focal point position of ultrasound, which is set to a region where a brain is positioned inside a skull in a living body, is input, the control unit outputs position data of an ultrasonic transducer, which allows the ultrasound to be applied to the input focal point position of the ultrasound.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p. ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 40/60 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux
10.
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DYSTROPHY COMPRISING ZALTOPROFEN AS ACTIVE INGREDIENT
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
MFC CO.,LTD. (République de Corée)
Inventeur(s)
Kim, Hyeon Soo
Kim, Do-Won
Hwang, Sung Kwan
Park, Chang Ha
Abrégé
The present invention provides a composition for preventing or treating muscular dystrophy, the composition comprising Zaltoprofen as an active ingredient. The composition according to the present invention increases the expression of utrophin, reduces the expression of myostatin, MAFbx, and MuRF1, and can inhibit muscle loss, increase muscle, and improve muscle function by inducing muscle differentiation and increasing the diameter of myotubes. Thus, the composition is expected to be used in various ways as medicines, quasi-medicines, fragrance materials, functional biomaterials, and functional food materials for alleviating, preventing, or treating muscular dystrophy.
A61K 31/38 - Composés hétérocycliques ayant le soufre comme hétéro-atome d'un cycle
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
11.
CATALYST FOR DEPOLYMERIZATION OF POLYCARBONATE-BASED RESIN, METHOD FOR PREPARING SAME, METHOD FOR DECOMPOSING POLYCARBONATE-BASED RESIN USING SAME, AND METHOD FOR RECOVERING CATALYST FOR DEPOLYMERIZATION OF POLYCARBONATE-BASED RESIN
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Jeongbin
Hong, Mooho
Seo, Jihun
Seo, Sojung
Lee, Seunghun
Lee, Eunji
Lee, Joonbum
Abrégé
The present invention relates to: a catalyst for depolymerization of a polycarbonate-based resin, comprising a compound represented by chemical formula 1; a method for preparing same; a method for decomposing a polycarbonate-based resin using same; and a method for recovering the catalyst for depolymerization of a polycarbonate-based resin.
B01J 31/02 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques
B01J 31/04 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des composés organiques ou des hydrures métalliques contenant des acides carboxyliques ou leurs sels
B01J 38/48 - Traitement par un liquide ou traitement en phase liquide, p. ex. en solution ou en suspension
C08J 11/28 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p. ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'azote, du soufre ou du phosphore
C07C 37/055 - Préparation de composés comportant des groupes hydroxyle ou O-métal liés à un atome de carbone d'un cycle aromatique à six chaînons par remplacement des groupes fonctionnels liés à un cycle aromatique à six chaînons par des groupes hydroxyle, p. ex. par hydrolyse par substitution d'un groupe lié au cycle par un oxygène, p. ex. d'un groupe éther
C07C 37/70 - SéparationPurificationStabilisationEmploi d'additifs par traitement physique
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Huy Kang
Jeong, Seonghoon
Lee, Hwejae
Lee, Sangho
Kang, Yeonjae
Pi, Daekwon
Park, Gunho
Abrégé
A method for detecting an anomaly, which is performed by a computing device including one or more processors according to some embodiments of the present disclosure may include: collecting a CAN message generated in a controller area network (CAN); generating first traffic time interval data and first payload data based on the CAN message; obtaining a first latent vector generated by inputting the first traffic time interval data into a first neural network model; obtaining a second latent vector generated by inputting the first payload data into a second neural network model; generating merged data in which the first latent vector and the second latent vector are merged; and determining whether the CAN message is anomalous by inputting the merged data into a third neural network model.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Chulwoo
Kang, Hyo Shin
Choi, Yoon Jae
Shin, Hwaseok
Sim, Chang-Min
Abrégé
Disclosed is a decision feedback equalizer, which includes a summator that receives a gray code-based PAM-4 signal, a first bit signal, and a second bit signal, and outputs an input voltage obtained by adding a preset coefficient to a voltage level of the PAM-4 signal in response to the first bit signal and the second bit signal, and a decoder that receives the input voltage and first to third reference voltages of the PAM-4 signal and outputs the first bit signal and the second bit signal, and the decoder includes a first comparator that outputs the first bit signal by comparing a magnitude of the input voltage with a magnitude of the first reference voltage, and a second comparator that outputs the second bit signal by comparing charge-discharge intensities of the input voltage and the second and third reference voltages.
H03B 19/14 - Production d'oscillations par multiplication ou division de la fréquence d'un signal issu d'une source séparée, n'utilisant pas de réaction positive au moyen d'un dispositif à décharge ou d'un dispositif à semi-conducteurs à plus de deux électrodes au moyen d'un dispositif à semi-conducteurs
H03B 19/18 - Production d'oscillations par multiplication ou division de la fréquence d'un signal issu d'une source séparée, n'utilisant pas de réaction positive en utilisant des dispositifs redresseurs non contrôlés, p. ex. des diodes redresseuses ou des diodes Schottky et des éléments comprenant des inductances et des capacités réparties
H01P 5/02 - Dispositifs de couplage du type guide d'ondes à coefficient de couplage invariable
15.
COMPOSITION AND KIT FOR DIAGNOSING AUTISM DISORDER
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Min Sik
Park, Ji Hwan
Mohammad, Hazara Begum
Minh, Hung Vu
Yoo, Hee Jeong
Lee, Yong Seok
An, Joon Yong
Abrégé
The present invention relates to a composition and a kit for diagnosing autism disorder. The composition, the kit, and a method for providing information according to the present invention can conveniently and effectively diagnose autism disorder in a small amount of blood by using multiple biomarkers in which proteins and metabolites have been combined in order to diagnose autism disorder.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
16.
CEREBRAL BLOOD FLOW MEASURING DEVICE USING NEAR-INFRARED RAYS
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Paik, Seung Ho
Lee, Seung Hyun
Abrégé
The present invention relates to a cerebral blood flow measuring device comprising: a flexible base configured to be transformed correspondingly to the shape of a head in close contact therewith; a plurality of light irradiation units provided on an installation surface, facing the head, of the flexible base; a plurality of light detection units provided on the installation surface; and an expansion unit configured to transform the flexible base. The cerebral blood flow measuring device using near-infrared spectroscopy according to the present invention can improve measurement accuracy by actively adjusting the pressure of the flexible base to thus bring the light irradiation units and the light detection units into close contact with each other according to the shape and size of the head.
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p. ex. de la concentration des gaz dans le sang ou de la valeur du pH du sang en utilisant des capteurs optiques, p. ex. des oxymètres à photométrie spectrale
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
17.
DEVICE AND METHOD FOR TRAINING DEEP LEARNING MODEL THAT SUPPORTS MULTI-LEVEL MULTI-LENGTH LATENT VECTORS
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
An, Taegun
Joo, Changhee
Abrégé
Disclosed is a device and method of training a deep learning model capable of using multi-level and multi-length latent vectors. The method of training the deep learning model is performed by a computing device including at least a processor and includes generating a basic model; and training the basic model, and the basic model includes a plurality of layer blocks each including at least one layer, and the layer blocks include first layer blocks configured to receive input data or output of a previous layer block to compress or encode data, or to output a latent vector corresponding to the input data and second layer blocks configured to receive the latent vector and the output of the previous layer block to restore or decode the data, or to derive inference results corresponding to the input data.
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Lee, Inkyu
Jeon, Young-Min
Fu, Zhilin
Abrégé
The present disclosure relates to a method of determining satellite orbital positions and routing for a Low Earth Orbit (LEO) satellite network, and the method calculates a communication throughput in each of a link between the transmitting base station and a satellite deployed on the first orbit, a link between satellites deployed on the first and second orbits, and a link between a satellite deployed on the second orbit and the receiving base station, and calculating a communication throughput in an entire link between the transmitting base station and the receiving base station on the basis of the communication throughput in each link, determines satellite orbital position variables and routing variables for maximizing the communication throughput in the entire link, and determines deployment of satellites on the first and second orbits on the basis of the satellite orbit position variables and routing variables.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Song, Yeong Hun
Seong, Jun Kyung
Lee, Wha Jin
Abrégé
The method for predicting Alzheimer's disease-related biomarkers according to the present disclosure involves a method executed by one or more processors of a computing device. The method comprises collecting medical images of a subject, preprocessing the collected medical images to generate training data, training a biomarker prediction model using the generated training data and the subject's demographic and clinical information, where the training includes assigning weights to the training data, and predicting Alzheimer's disease-related biomarkers for a patient using the trained biomarker prediction model.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p. ex. pour des dossiers électroniques de patients
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p. ex. pour analyser les cas antérieurs d’autres patients
20.
RESOURCE BLOCK SCHEDULING METHOD, AND ELECTRONIC DEVICE PERFORMING SAME METHOD
Samsung Electronics Co., Ltd. (République de Corée)
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kwon, Hyungtae
Lee, Inkyu
Lee, Hongju
Kim, Sangeon
Min, Seunghyun
Abrégé
A resource block scheduling method and an electronic device performing the method are disclosed. An electronic device according to various embodiments may comprise: at least one processor, comprising processing circuitry, and a memory electrically connected to at least one processor and storing instructions executable by the processor, wherein at least one processor, individually and/or collectively, is configured to execute the instructions and to:
A resource block scheduling method and an electronic device performing the method are disclosed. An electronic device according to various embodiments may comprise: at least one processor, comprising processing circuitry, and a memory electrically connected to at least one processor and storing instructions executable by the processor, wherein at least one processor, individually and/or collectively, is configured to execute the instructions and to:
based on channel quality information indexes (CQIs) relating to a plurality of terminals, acquire achievable rates based on resource blocks being allocated to the plurality of terminals; and input the achievable rates to a trained neural network model to output a schedule for allocation of the resource blocks to the plurality of terminals, and the neural network model is configured to be trained to collect the training CQIs relating to the plurality of terminals, acquire, based on the training CQIs, training achievable rates based on the resource blocks being allocated to the plurality of terminals, and output the schedule, in which the sum of the rates for the plurality of terminals is maximized and fairness indexes for the plurality of terminals satisfy a configured fairness condition, using the input training achievable rates.
H04W 72/121 - Planification du trafic sans fil pour les groupes de terminaux ou d’utilisateurs
H04W 72/542 - Critères d’affectation ou de planification des ressources sans fil sur la base de critères de qualité en utilisant la qualité mesurée ou perçue
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Cheon, Cheol-Hong
Park, Jinjae
Seo, Juan
Abrégé
The present invention relates to a method for efficiently preparing rucaparib for a PET image. More specifically, the present invention relates to an improved preparation method for synthesizing [18F]-rucaparib in excellent yield by means of a pathway for synthesizing a pinacol boronate derivative, which is a key intermediate, by using, as a starting material, a 2-iodoaniline derivative prepared by a novel synthesis method.
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
C07D 209/18 - Radicaux substitués par des atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Cheon, Cheol-Hong
Park, Jinjae
Abrégé
The present invention relates to a method for efficiently preparing 2-amino-4-fluoro-6- methoxycarbonylcinnamonitrile. More specifically, the present invention relates to an improved preparation method for synthesizing 2-amino-4-fluoro-6-methoxycarbonylcinnamonitrile, which is a key intermediate in preparing rucaparib with excellent yield through a novel synthesis route using, as a starting material, alkyl 5-fluoro-2-methyl-3-nitrobenzoate rather than a conventional 2-iodoaniline derivative.
C07C 253/30 - Préparation de nitriles d'acides carboxyliques par des réactions n'impliquant pas la formation de groupes cyano
C07C 255/42 - Nitriles d'acides carboxyliques ayant des groupes cyano liés à des atomes de carbone acycliques ayant des groupes cyano liés à des atomes de carbone acycliques d'un squelette carboné contenant au moins un cycle aromatique à six chaînons le squelette carboné étant substitué de plus par des atomes d'azote liés par des liaisons simples et n'étant pas liés de plus à d'autres hétéro-atomes
C07C 255/64 - Nitriles d'acides carboxyliques contenant des groupes cyano et des atomes d'azote liés de plus à d'autres hétéro-atomes, autres que les atomes d'oxygène de groupes nitro ou nitroso, liés au même squelette carboné avec les atomes d'azote liés de plus à des atomes d'oxygène
C07C 255/41 - Nitriles d'acides carboxyliques ayant des groupes cyano liés à des atomes de carbone acycliques ayant des groupes cyano liés à des atomes de carbone acycliques d'un squelette carboné contenant au moins un cycle aromatique à six chaînons le squelette carboné étant substitué de plus par des groupes carboxyle, autres que des groupes cyano
23.
DEVICE FOR GENERATING ELECTRICITY THROUGH MULTI-TYPE ION CONTROL BASED ON DONNAN EFFECT, AND ELECTRICITY GENERATING DEVICE HAVING LAMINATED STRUCTURE
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Han, Chang Soo
Kim, Jung Soo
Abrégé
Disclosed is an electricity generation device. The present invention provides an electricity generation device, including: a first electrolyte, selectively permeable membrane, and second electrolyte in a chamber thereof, wherein each of the first electrolyte and the second electrolyte includes at least two types of ions, and at least three types of ions are included in the first electrolyte and the second electrolyte, the selectively permeable membrane selectively permeates at least one type of ions among the at least three types of ions to cause Donnan effect between the first electrolyte and the second electrolyte.
H01M 8/22 - Éléments à combustible dans lesquels le combustible est à base de matériaux comprenant du carbone, de l'oxygène ou de l'hydrogène et d'autres élémentsÉléments à combustible dans lesquels le combustible est à base de matériaux comprenant uniquement des éléments autres que le carbone, l'oxygène ou l'hydrogène
H01M 8/18 - Éléments à combustible à régénération, p. ex. batteries à flux REDOX ou éléments à combustible secondaires
24.
DEVICE AND METHOD FOR PRIVACY-PRESERVING ECG DATA COLLECTION FOR ARRHYTHMIA CLASSIFICATION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Chung, Yon Dohn
Lee, Hyubjin
Kim, Minsoo
Abrégé
Disclosed is a privacy-preserving electrocardiogram (ECG) data collecting method for arrhythmia classification. The privacy-preserving ECG data collecting method is performed by a computing device including at least a processor and includes training a feature extraction model, a personal identification model, and an arrhythmia classification model using learning data that includes ECG data with a predetermined length; and training a noise model, and the feature extraction model receives the ECG data as input and outputs ECG features, the personal identification model receives the ECG features as input and identifies an individual corresponding to the ECG features, the arrhythmia classification model receives the ECG features as input and classifies arrhythmia corresponding to the ECG features, and the noise model generates noise with the same length as that of the ECG features.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
A61B 5/349 - Détection de paramètres spécifiques du cycle de l'électrocardiogramme
Samsung Electronics Co., Ltd. (République de Corée)
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Park, Jongsun
Kim, Dongsu
Park, Seonggeon
Abrégé
Disclosed is a field programmable gate array device including a plurality of lookup tables each storing data. Each lookup table includes a cell array including cells connected to a plurality of word lines, a drive circuit connected to the cell array through the plurality of word lines, and a peripheral circuit connected to the cell array through a plurality of bit lines and source lines, and configured to control the drive circuit. The drive circuit drives a first word line among the word lines based on first input signals. The peripheral circuit performs a data write operation on a first cell connected to the first word line, based on a first command and a second input signal, and performs a data read operation on the first cell connected to the first word line, based on a second command and the second input signal.
G06F 3/06 - Entrée numérique à partir de, ou sortie numérique vers des supports d'enregistrement
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
H03K 19/17728 - Blocs logiques reconfigurables, p. ex. tables de consultation
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDAITON (République de Corée)
Inventeur(s)
Kim, Bo Ram
Hur, Minkyu
Lim, Haet Nim
Lee, Jisun
Oh, Sang Cheul
Jung, Sang Taek
Abrégé
The present disclosure relates to a novel human antibody or an antigen-binding fragment thereof that recognizes the SMO (smoothened) protein as an antigen and binds specifically thereto. The antibody of the present disclosure binds specifically to the SMO protein, which is directly involved in major cancer progression processes such as proliferation, migration, invasion and metastasis of cancer cells, and blocks the progression those processes. Therefore, it can be usefully used as a therapeutic agent for various cancers such as colon cancer, etc., resistant cancer, metastatic cancer, or recurrent cancer.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Hwang, Eenjun
Shim, Jonghwa
Abrégé
The present invention relates to a building drawing design device and method, the building drawing design method comprising the steps of: acquiring basic data for generating a building drawing; using a trained learning model to acquire a generation drawing corresponding to the basic data; and performing post-processing on the generation drawing so as to acquire a resulting drawing corresponding to the basic data, wherein the trained learning model can be acquired by the steps of: acquiring at least one reference drawing corresponding to at least one original drawing; removing some or all of the space of the at least one reference drawing so as to generate at least one input drawing corresponding to the at least one reference drawing; and training the learning model by using the at least one reference drawing and the at least one input drawing.
G06F 30/27 - Optimisation, vérification ou simulation de l’objet conçu utilisant l’apprentissage automatique, p. ex. l’intelligence artificielle, les réseaux neuronaux, les machines à support de vecteur [MSV] ou l’apprentissage d’un modèle
G06F 30/13 - Conception architecturale, p. ex. conception architecturale assistée par ordinateur [CAAO] relative à la conception de bâtiments, de ponts, de paysages, d’usines ou de routes
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Choi, Wonmi
Yoo, Yeonho
Yang, Gyeongsik
Yoo, Chuck
Abrégé
Disclosed is a device and method for lightweight container packet processing in an Internet of things (IoT) environment. A packet processing method is performed by a server that provides a container environment to an IoT device and includes receiving a packet from a container assigned to the IoT device; determining a packet processing path to process the packet; processing the packet according to the determined packet processing path; and transmitting the packet of which packet processing is completed to an external network.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Young-Sun
Abrégé
The present invention relates to miRNA-4449, which is a biomarker that can be used to diagnose nonalcoholic steatohepatitis, and at least one miRNA selected from the group consisting of miRNA-15, miRNA-21, miRNA-29, miRNA-126, miRNA-151, miRNA-183, and miRNA-192. The prognosis of nonalcoholic steatohepatitis among nonalcoholic fatty liver diseases is poor unlike simple steatosis. According to the present invention, the level of the miRNA can be measured in the serum of a patient to provide an accurate diagnostic result of nonalcoholic steatohepatitis, thus making it possible to eliminate side effects caused by conventional invasive test methods, and enabling early diagnosis and appropriate treatment of steatohepatitis in a simple and economical manner.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Hwang, Suk Won
Han, Won Bae
Ko, Gwan Jin
Abrégé
Disclosed is an implantable monitoring and treatment device. The implantable monitoring and treatment device comprises: a jacket unit which surrounds an organ in the body and is made of an elastic material so as to deform according to the expansion and contraction of the organ; and a biometric signal measurement unit which is provided in the jacket unit and measures biometric signals from the organ. The jacket unit includes: a first pad which has a prescribed area and is in close contact with one region of the organ; a second pad which has a prescribed area and is in close contact with another region of the organ; and at least one fastening string connecting the first pad and the second pad.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Cho, Il Joo
Shin, Hyogeun
Abrégé
Disclosed are a signal measurement device for measuring signals of a plurality of organoids, and a control method for controlling the signal measurement device. The signal measurement device may comprise: a well plate in which chambers accommodating organoids are disposed; a probe array including probes in which electrodes are disposed; a cover in which the probe array is disposed; a gap adjustment unit for adjusting a gap between the well plate and the probe array; and a control unit for controlling the gap adjustment unit to adjust the gap between the well plate and the probe array on the basis of changes in an electrical signal measured by the electrodes.
G01B 7/16 - Dispositions pour la mesure caractérisées par l'utilisation de techniques électriques ou magnétiques pour mesurer les déformations dans un solide, p. ex. au moyen d'une jauge de contrainte à résistance
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Cho, Il Joo
Shin, Hyogeun
Abrégé
A screening device for analyzing multiple organoids is disclosed. The screening device comprises: a microfluidic chip in which one or more microfluidic channels through which a drug flows are arranged; a well plate in which a plurality of chambers accommodating organoids are arranged; and a probe array in which probes inserted into the organoids so as to measure a signal in each organoid are arranged in an array form, wherein a first microfluidic channel among the one or more microfluidic channels is arranged to be adjacent to a first chamber array in which some of the chambers are arranged in an array form, and the drug flowing in the first microfluidic channel can be delivered to each organoid accommodated in the first chamber array through porous films having different porosities.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Jung, Sang Taek
Kyung, Munsu
Ko, Sanghwan
Jo, Migyeong
Kim, Suyeon
Ko, Woo Hyung
Abrégé
Provided are Fc variants having improved half-life by binding to and unbinding from FcRn in a pH-dependent manner, which have improved capacity to selectively bind to Fcγ receptors. The human Fc domain variants have lower capacity to bind to immune-inhibiting receptor FcγRIIb and have higher capacity to bind to immune activating receptor FcγRIIIa (increased A/I ratio) than a wild-type human antibody Fc domain and conventional antibodies approved as antibody therapeutic agents, thereby having remarkably improved ADCC induction ability and having maximized half-life in blood in which excellent pH-selective FcRn binding and unbinding capacity is exhibited, and thus bind to numerous peptide drug therapeutics having a low half-life and retention time in the body to enable the peptide drug therapeutics to have an increased blood half-life and exhibit long-term drug efficacy, and can maximize the immune mechanism of therapeutic protein drugs to be effectively used as an improved antibody drug.
C07K 16/32 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des produits de traduction des oncogènes
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p. ex. un fragment Fc
34.
USE OF TCTP AS BIOMARKER FOR PREDICTING EFFICACY, PROGNOSIS OF IMMUNOTHERAPY OR RESISTANCE THERETO, AND TARGET OF IMMUNOTHERAPY FOR ENHANCING EFFICACY
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Tae Woo
Lee, Hyo Jung
Abrégé
Disclosed herein are a method and a biomarker for predicting efficacy and prognosis of or resistance to an immunotherapy. The use of the biomarkers (TCTP, EGFR, AKT, MCL1, and/or CXCL10) of the present disclosure allows the prediction of resistance to or prognosis of a cancer immunotherapeutic agent and the selection of a therapy guaranteeing therapeutic benefit, thereby finding advantageous applications in treating cancers or tumors resistant to cancer immunotherapeutic agents.
G01N 33/574 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour le cancer
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
35.
NOVEL CHROMENE-BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Seo, Jae Hong
Nam, Kee Dal
Kim, Ji Young
Kim, Yoon Jae
Jung, Eun-Sun
Kang, Yong Koo
Park, Min Su
Kim, Seong Jae
Lee, Sang Yoon
Abrégé
The present invention relates to a chromene-benzimidazole derivative or a pharmaceutically acceptable salt thereof, and a composition containing the derivative as an active ingredient for preventing or treating cancer. The chromene-benzimidazole derivative of the present invention is activated in cancer cells to inhibit tubulin polymerization and suppress the C-terminal domain of Hsp90, thereby blocking the cell cycle of cancer cells, inducing apoptosis, and inhibiting the activity of oncoproteins, and thus can be used as a novel dual-target anticancer drug for preventing or treating cancer, preferably for preventing or treating triple-negative breast cancer.
C07D 405/12 - Composés hétérocycliques contenant à la fois un ou plusieurs hétérocycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle et un ou plusieurs hétérocycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne contenant des hétéro-atomes comme chaînons
A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p. ex. benzimidazoles
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
Korea University Research And Business Foundation (République de Corée)
Inventeur(s)
Kim, Taekyun
Shim, Jaewon
Chung, Jaejin
Abrégé
A semiconductor device includes a capacitor including a first electrode, a second electrode, and a dielectric layer between the first electrode and the second electrode, where at least one of the first electrode and the second electrode includes a nanolaminate electrode, the nanolaminate electrode includes a plurality of first material layers and a plurality of second material layers, the plurality of first material layers and the plurality of second material layers being alternately arranged, the plurality of first material layers includes indium oxide (In2O3), the plurality of second material layers includes molybdenum oxide (MoOx), each of the plurality of first material layers has a thickness between about 2 angstroms to about 6 angstroms, and each of the plurality of second material layers includes a monolayer of molybdenum oxide.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Cho, Zang-Hee
Lee, Haigun
Lee, Sang Zee
Suk, Dae-Hwan
Han, Junhee
Jeong, Hyejin
Baek, Seung-Min
Abrégé
Disclosed is a qubit system based on magnetic resonance, according to some embodiments of the present disclosure. The qubit system may comprise: a magnet having a space provided on the inside thereof; a qubit sample which is disposed in the space provided on the inside of the magnet and contains a material capable of quantum state transition; a gradient coil which is disposed on the outside of the qubit sample to correspond to the qubit sample on the inside of the magnet and generates a gradient magnetic field in the space on the inside of the magnet, which has the qubit sample contained therein; an RF transmitting coil part disposed between the qubit sample and the gradient coil on the inside of the magnet, to apply radio frequency (RF) pulses to the qubit sample and control a quantum state of the qubit sample; and an RF receiving coil disposed on the inside of the magnet to receive RF signals emitted from the qubit sample due to the applied RF pulses.
G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p. ex. couplage ou commande de qubit
G06N 10/20 - Modèles d’informatique quantique, p. ex. circuits quantiques ou ordinateurs quantiques universels
G06N 20/10 - Apprentissage automatique utilisant des méthodes à noyaux, p. ex. séparateurs à vaste marge [SVM]
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p. ex. calcul quantique ou logique à un électron
38.
BASE STATION FOR RECONSTRUCTING DOWNLINK CHANNEL IN MULTI-INPUT-MULTI-OUTPUT COMMUNICATION SYSTEM, AND DOWNLINK CHANNEL RECONSTRUCTION METHOD THROUGH BASE STATION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Nam Yoon
Han, Deokhwan
Abrégé
A method of reconstructing a downlink (DL) channel by a base station in a multiple-input-multiple-output (MIMO) communication system includes: estimating UL channel information on the basis of an uplink (UL) pilot signal received from a user equipment; extracting at least one key parameter among common parameters of the UL channel and the DL channel from the estimated UL channel information; estimating DL channel information using the UL channel information and the at least one key parameter; and reconstructing the DL channel by correcting an error between the estimated DL channel information and actual DL channel information.
H04L 5/00 - Dispositions destinées à permettre l'usage multiple de la voie de transmission
H04W 72/1273 - Jumelage du trafic à la planification, p. ex. affectation planifiée ou multiplexage de flux de flux de données en liaison descendante
H04W 72/21 - Canaux de commande ou signalisation pour la gestion des ressources dans le sens ascendant de la liaison sans fil, c.-à-d. en direction du réseau
H04W 72/54 - Critères d’affectation ou de planification des ressources sans fil sur la base de critères de qualité
Korea University Research and Business Foundation (République de Corée)
GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Inventeur(s)
Lee, Eun Ji
Lee, Chang Whan
Ahn, Dong June
Kim, In Hye
Kim, Ha Yeon
Lee, Ye Dam
Abrégé
The present invention provides a composition for freezing control, a composition for freezing a cell, and a composition for freezing a food, which include a compound in which 2 to 5 amino acids, for example, 2, 3, 4, or 5 amino acids are connected to fluorenylmethyloxycarbony (Fmoc) through peptide bonding.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Oh, Chaeyoun
Abrégé
An intestinal content delivery device for an intestinal fistula patient according to one embodiment of the present invention comprises: a nutrient delivery tube having a nutrient delivery passage inserted into an intestinal fistula of a user to deliver nutrients between an upper intestinal fistula and a lower intestinal fistula; and a nutrient supply tube coupled to one side of the nutrient delivery tube so as to communicate with the nutrient delivery passage. The nutrient delivery tube may comprise: an upper intestinal fistula insertion tube that is provided to be insertable into the upper intestinal fistula, has a first nutrient delivery passage, and has at least one first through-hole formed at one end thereof so that nutrients present in the upper intestinal fistula can flow therethough; and a lower intestinal fistula insertion tube that is provided to be insertable into the lower intestinal fistula, has a second nutrient delivery passage which communicates with the first nutrient delivery passage, and has at least one second through-hole formed at one end thereof so that nutrients delivered from the upper intestinal fistula through the first through-hole and the first nutrient delivery passage can be delivered to the lower intestinal fistula.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
Korea University Research and Business Foundation (République de Corée)
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
Korea National Institute of Health (République de Corée)
Inventeur(s)
Baek, Daehyun
Chang, Hee Ryung
Yang, Jeong-Sun
Lee, Hansaem
Park, Man-Seong
Park, Heedo
Kim, Yoon Ki
Chang, Jeeyoon
Park, Joori
Lee, Joo-Yeon
Kim, Kyung-Chang
Abrégé
The present disclosure relates to a TIS-L targeting antisense oligonucleotide that inhibits the viral replication of SARS-COV-2 and antiviral use thereof. Since the TIS-L targeting antisense oligonucleotide according to the present disclosure has a simple structure, it is easy to mass produce, and as it exhibits antiviral efficacy of 90% or more even at low doses against the original strain and various modified strains of the virus, it can be advantageously utilized in the development of COVID-19 treatment.
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Lee, In Hwan
Abrégé
Disclosed is a Light-Emitting Device-Thin Film Transistor (LED-TFT) integration structure, comprising a substrate comprising a light emitting area and a driving area; a metal reflective film formed on the substrate; a buffer layer formed on the metal reflective film; LED disposed in the light emitting area; a protective layer formed on the LED; a thin film transistor disposed in the driving area and configured to drive the LED; and an ohmic contact metal for electrically connecting a cathode of the LED with the metal reflective film, wherein the LED and the thin film transistor are integrally formed on the substrate.
H01L 25/16 - Ensembles consistant en une pluralité de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide les dispositifs étant de types couverts par plusieurs des sous-classes , , , , ou , p. ex. circuit hybrides
H01L 27/12 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des éléments de circuit passif intégrés avec au moins une barrière de potentiel ou une barrière de surface le substrat étant autre qu'un corps semi-conducteur, p.ex. un corps isolant
H01L 33/12 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure de relaxation des contraintes, p.ex. couche tampon
H01L 33/46 - Revêtement réfléchissant, p.ex. réflecteur de Bragg en diélectriques
H01L 33/62 - Dispositions pour conduire le courant électrique vers le corps semi-conducteur ou depuis celui-ci, p.ex. grille de connexion, fil de connexion ou billes de soudure
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Hwang, Cheol-Sang
Mun, Sang-Hyeon
Abrégé
The present invention relates to a POMC-specific antibody and use thereof, and use of Marchf6 for treating metabolic diseases. It has been found that the cytosolic accumulation of POMC, which is an appetite-regulating hormone precursor protein, induces ER stress and ferroptosis, and Marchf6 degrades POMC by directly binding thereto, causing the translocation of POMC into ER. Also, it has been confirmed that a produced POMC-specific antibody can specifically detect POMC accumulated in the cytosol of POMC neurons. Therefore, these can be used for the diagnosis and treatment of diseases associated with POMC accumulation or Marchf6 dysfunction. It has also been found that ER stress and ferroptosis caused by accumulation of POMC in the cytosol are regulated. In particular, it was confirmed in vivo that Marchf6 deficiency in POMC neurons causes metabolic disorders. Therefore, Marchf6 can be effectively used for the prevention or treatment of metabolic diseases, including obesity.
C07K 14/665 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains dérivés de pro-opiomélanocortine, pro-enképhaline ou pro-dynorphine
C07K 16/26 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des hormones
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Jae Young
Baek, Yoo Sang
Abrégé
Disclosed is a method and apparatus for determining diagnosis result data by using a thermal image. A method for determining diagnosis result data may comprise the steps of: acquiring a first thermal image indicating a temperature change of skin, to which thermal stimulation has been applied, over time; acquiring a second thermal image indicating a temperature change of skin, to which cold stimulation has been applied, over time; extracting a temperature restoration feature of the skin from each of the first thermal image and the second thermal image; and determining diagnosis result data related to the skin on the basis of the temperature restoration feature extracted from the first thermal image and the temperature restoration feature extracted from the second thermal image.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p. ex. basé sur des systèmes experts médicaux
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p. ex. DICOM, HL7 ou PACS
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p. ex. l’édition
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le calcul des indices de santéTIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicalesTIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
45.
CONTROL METHOD FOR BLOCKCHAIN-BASED EVIDENCE DATA NOTARIZATION SYSTEM, AND RECORDING MEDIUM AND SYSTEM FOR PERFORMING SAME
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
In, Hoh Peter
Choi, Jihyok
Abrégé
There is provided with a blockchain-based evidence data notarization system comprising a user terminal for transmitting the evidence data in accordance with a notarization request; a notary server for transmitting the generated hash value to the user terminal and a notary terminal, respectively; and a blockchain server for receiving a signature written in the hash value from the user terminal and the notary terminal, respectively and generating a smart contract block.
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kim, Dong-Wan
Seo, Seung-Deok
Hwang, Suk-Ho
Abrégé
The present invention can provide a method for preparing a sulfide-based solid electrolyte in a short time using a solvothermal synthesis method. In addition, the present invention may provide a sulfide-based solid electrolyte prepared by the method. In addition, the present invention may provide an electrode for an all-solid-state battery including the sulfide-based solid electrolyte.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
47.
ZWITTERIONIC POLYMER-BASED AQUEOUS ELECTROLYTE HAVING HIGH POTENTIAL STABILITY WINDOW THROUGH CONTROL OF HYDRATION LAYER AND MANUFACTURING METHOD THEREOF
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kang, Yongmook
Seo, Ji-Hun
Lee, Suwon
Kim, Bitgaram
Park, Sang Hyun
Jang, Seokhyun
Abrégé
The present invention relates to a zwitterionic polymer-based aqueous electrolyte having a high potential stability window through control of a hydration layer, and a manufacturing method thereof. According to one embodiment, a zwitterionic polymer-based aqueous electrolyte having a high potential stability window through control of a hydration layer may be provided, the zwitterionic polymer-based aqueous electrolyte including a polymer hydrogel having a three-dimensional network structure composed of: a zwitterionic polymer structure derived from an ionic polymer monomer and polymerized and crosslinked through a crosslinker and an initiator; and a hydration layer formed on the surface of the zwitterionic polymer structure.
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
H01M 10/42 - Procédés ou dispositions pour assurer le fonctionnement ou l'entretien des éléments secondaires ou des demi-éléments secondaires
H01M 10/36 - Accumulateurs non prévus dans les groupes
C08F 230/02 - Copolymères de composés contenant un ou plusieurs radicaux aliphatiques non saturés, chaque radical ne contenant qu'une seule liaison double carbone-carbone et contenant du phosphore, du sélénium, du tellure ou un métal contenant du phosphore
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kang, Yongmook
Seo, Ji-Hun
Lee, Suwon
Kim, Bitgaram
Park, Sang Hyun
Abrégé
The present invention relates to an electrolyte using a high-dielectric-constant zwitterionic material, and a preparation method therefor. According to an embodiment, the provided electrolyte using a high-dielectric-constant zwitterionic material, which is for a secondary battery using a metal anode material as an anode, comprises an electrolyte mixture composed of: an organic electrolyte including an organic solvent and a metal salt; and a zwitterionic compound having a weight average molecular weight that satisfies a range of 100-60,000 g/mol and having a zwitterion.
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
H01M 10/0567 - Matériaux liquides caracterisés par les additifs
H01M 10/42 - Procédés ou dispositions pour assurer le fonctionnement ou l'entretien des éléments secondaires ou des demi-éléments secondaires
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 4/134 - Électrodes à base de métaux, de Si ou d'alliages
C08F 220/06 - Acide acryliqueAcide méthacryliqueLeurs sels métalliques ou leurs sels d'ammonium
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Nam Yoon
Choi, Geon
Abrégé
The present disclosure provides a state estimation apparatus of estimating a current state of an object based on state information and observation information for dynamically replicating the object, the state estimation apparatus including an input unit that receives the observation information, and a current state estimation unit that generates current state estimation information through the observation information, wherein the current state estimation unit includes a prediction information generation unit that generates state prediction information through inputting past state estimation information obtained by delaying the current state estimation information by one time unit into a previously prepared state prediction model, and a prediction information correction unit that calculates a Kalman gain matrix associated with a degree of correction of the state prediction information through artificial neural network(s), and corrects the state prediction information through the observation information and the Kalman gain matrix to generate the current state estimation information.
G01S 7/41 - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe utilisant l'analyse du signal d'écho pour la caractérisation de la cibleSignature de cibleSurface équivalente de cible
G01S 13/06 - Systèmes déterminant les données relatives à la position d'une cible
50.
METHOD FOR CONTROLLING BLOCKCHAIN-BASED SHARED ASSET TRANSACTION SYSTEM, AND RECORDING MEDIUM AND SYSTEM FOR PERFORMING SAME
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
In, Hoh Peter
Choi, Jihyok
Abrégé
Provided with a blockchain-based shared asset trading system for tokenizing and trading a shared asset comprising a plurality of sharer terminals, provided on a sharer side, for transmitting an original warranty containing the appraisal result of the shared asset and transmitting a warranty in which the sharer's signature has been entered to the original warranty; a blockchain network for receiving and storing the original warranty in a smart contract block, issuing a token based on the smart contract block and generating an electronic wallet in which the token is stored; and an electronic wallet management server for receiving the warranty in which the signature has been entered from the plurality of sharer terminals and transmitting a transaction including the warranty in which the signature has been entered to the original warranty.
G06Q 20/38 - Protocoles de paiementArchitectures, schémas ou protocoles de paiement leurs détails
G06Q 20/36 - Architectures, schémas ou protocoles de paiement caractérisés par l'emploi de dispositifs spécifiques utilisant des portefeuilles électroniques ou coffres-forts électroniques
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Jun, Yongseok
Kang, Yoonmook
Lee, Chanyong
Lee, Chang Hyun
Abrégé
Disclosed is a photovoltaic module including an encapsulation part, a plurality of solar cells disposed in the encapsulating part such that angles thereof with respect to a height direction of the encapsulation part is 30 degrees to 90 degrees, and impact absorption parts disposed between the plurality of solar cells in the encapsulation part.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Seon Wook
Kim, Seok-Young
Abrégé
An embodiment of the present invention provides a processing-in-memory memory device comprising: a memory bank including a memory array for receiving a memory request from a memory controller, and a PIM engine for executing processing-in-memory according to the PIM instruction; and a processing-in-memory (PIM) control unit for controlling the processing-in-memory of the PIM engine by identifying a PIM instruction corresponding to the memory request, and storing addressing mode selection information for selecting one among an indirect address and a direct address according to the identified PIM instruction, wherein when the indirect address is used, the PIM control unit uses a register value of the processing-in-memory control unit as a base register value, reads an immediate value in the PIM instruction, a register value of the PIM engine, or an offset value of the memory bank, and generates an effective address for the processing-in-memory in an indirect addressing mode.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
KOREA INSTITUTE OF SCIENCE AND TECHMOLOGY (République de Corée)
Inventeur(s)
Choi, Myunghwan
Kim, Seonghoon
Chong, Kyuha
Yang, Sungwook
Abrégé
Disclosed are a patterned optical stimulation device and method. The patterned optical stimulation device according to one aspect includes: an imaging unit which generates a skin tissue image; a diagnosis unit which detects a region of interest from the skin tissue image and diagnoses the detected region of interest; and an optical stimulation unit which forms patterned treatment light corresponding to the region of interest and irradiates the region of interest with the formed patterned treatment light.
SEOUL NATIONAL UNIVERSITY HOSPITAL (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Woo Hyung
Oh, Byung Mo
Seo, Han Gil
Hyun, Sung Eun
Kim, Jung Hyun
Kim, Dong Joo
Kim, Hak Seung
Han, Tae Seong
Abrégé
The present invention provides a method and system for prediction of fall on the basis of EMG signals in a stroke patient. The method for prediction of fall on the basis of EMG signals in a stroke patient, according to one embodiment of the present invention, comprises the steps of: attaching an EMG sensor to a first part among lower limb muscles of the patient; measuring the EMG signals of the patient performing an exercise motion for collecting the EMG signals, by means of the EMG sensor attached to the first part; and determining a fall risk of the patient on the basis of the measured EMG signals.
IN-SITU TRUNCATION METHOD FOR NONESSENTIALS-INDUCING APTAMER IN APTAMER-PROTEIN CONJUGATE AND TRUNCATED APTAMER THAT IS PREPARED BY SAME METHOD AND BINDS WITH HIGH AFFINITY TO VASPIN
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (République de Corée)
Inventeur(s)
Gu, Man Bock
Kim, Eun Ryung
Lee, Su Jin
Abrégé
The present invention relates to: an in-situ truncation method for a nonessentials-inducing aptamer in an aptamer-protein conjugate; and a truncated aptamer that is prepared by the method and binds with high affinity to vaspin. Particularly, the present invention relates to: an in-situ aptamer truncation method comprising the steps of (1) mixing a target protein and an aptamer capable of binding to the target protein to form a conjugate of the aptamer and the target protein and (2) treating the conjugate of the aptamer and the target protein with exonuclease to remove nonessentials of the aptamer that do not bind to the target protein; a truncated aptamer that is prepared by the method and consists of an essential sequence that binds to the target protein; a kit for detecting a target protein, comprising the truncated aptamer; a method for preparing a truncated aptamer that binds to a vaspin protein, by the in-situ aptamer truncation method; and a truncated DNA aptamer that is prepared by the method and consists of an essential sequence that binds to a vaspin protein.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Hong, Chang Seop
Choe, Jong Hyeak
Abrégé
The present invention relates to a carbamate amine/amine-grafted metal-organic framework-based carbon dioxide adsorbent. According to the present invention, the provided carbon dioxide adsorbent maintains adsorption performance even in a flue gas environment containing high-concentration moisture and has improved reusability and stability.
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
C07C 269/04 - Préparation de dérivés d'acide carbamique, c.-à-d. de composés contenant l'un des groupes l'atome d'azote ne faisant pas partie de groupes nitro ou nitroso à partir d'amines avec formation de groupes carbamate
C07C 271/28 - Esters des acides carbamiques ayant des atomes d'oxygène de groupes carbamate liés à des atomes de carbone acycliques avec l'atome d'azote d'au moins un des groupes carbamate lié à un atome de carbone d'un cycle aromatique à six chaînons à un atome de carbone d'un cycle aromatique à six chaînons non condensé
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
57.
METHOD AND APPARATUS FOR OPTIMALLY OPERATING HYDROGEN AND ELECTRIC VEHICLE CHARGING STATION BY CONSIDERING HPS MARKET
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Choi, Sungyun
Woo, Hyeon
Abrégé
Disclosed is a method for scheduling a hydrogen and electric vehicle charging station, linked with renewable energy, by considering the HPS market. The scheduling method is performed by a computing device including a processor, and comprises the steps of: modeling the charging demand of the hydrogen and electric vehicle charging station; and scheduling the hydrogen and electric vehicle charging station through second-order conic programming (SOCP) repair optimization on the basis of the modeled charging demand, wherein the scheduling step includes the steps of: setting an objective function defined by an equation; and setting at least one constraint.
G06Q 50/40 - Procédés d’affaires s’appliquant à l’industrie du transport
G06Q 10/06 - Ressources, gestion de tâches, des ressources humaines ou de projetsPlanification d’entreprise ou d’organisationModélisation d’entreprise ou d’organisation
G06Q 10/04 - Prévision ou optimisation spécialement adaptées à des fins administratives ou de gestion, p. ex. programmation linéaire ou "problème d’optimisation des stocks"
B60L 53/50 - Stations de charge caractérisées par des moyens d’emmagasinage ou de production d'énergie
B60L 58/40 - Procédés ou agencements de circuits pour surveiller ou commander des batteries ou des piles à combustible, spécialement adaptés pour des véhicules électriques pour la commande d'une combinaison de batteries et de piles à combustible
H02J 3/38 - Dispositions pour l’alimentation en parallèle d’un seul réseau, par plusieurs générateurs, convertisseurs ou transformateurs
58.
MRAM BASED ON THE FERROMAGNETIC FILM WITH IN-PLANE BIAXIAL ANISOTROPY
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Sanghoon
Abrégé
Disclosed is a magnetic random access memory (MRAM) device based on a ferromagnetic film with in-plane biaxial anisotropy. The MRAM device includes a substrate and a ferromagnetic layer formed on the substrate, and the ferromagnetic layer has biaxial anisotropy. In the present invention, information can store in a cell only with current pulses, which switches magnetization between easy-axes, because spin-orbit field component along easy axes changes with current direction. This may lead to an increase in the operating efficiency of the memory device.
G11C 11/16 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments magnétiques utilisant des éléments dans lesquels l'effet d'emmagasinage est basé sur l'effet de spin
H01F 1/147 - Alliages caractérisés par leur composition
H10B 61/00 - Dispositifs de mémoire magnétique, p. ex. dispositifs RAM magnéto-résistifs [MRAM]
PHARMACEUTICAL COMPOSITION CONTAINING AS ACTIVE INGREDIENT COMPOUND CONJUGATED TO G4 STRUCTURES OF CORONAVIRUSES FOR PREVENTION OR TREATMENT OF CORONAVIRUS INFECTIOUS DISEASES
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Kyeong Kyu
Song, Moon Jung
Park, Man-Seong
Ahn, Jin-Hyun
Razzaq, Maria
Ravichandran, Subramaniyam
Han, Ji Ho
Kim, Jae Hyun
Abrégé
The present invention relates to a composition for preventing or treating coronavirus infectious diseases, comprising a compound that binds to G4 structures of coronaviruses. Since the compound according to the present invention can bind to G4 structures of coronaviruses to stabilize the G4 structures, reduce the protein expression of coronaviruses, and effectively inhibit cell infection by viruses, the compound is expected to be used in the prevention or treatment of coronavirus infectious diseases.
A61K 31/409 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil ayant quatre de ces cycles, p. ex. dérivés de la porphine, bilirubine, biliverdine
A61K 31/444 - Pyridines non condenséesLeurs dérivés hydrogénés contenant d'autres systèmes hétérocycliques contenant un cycle à six chaînons avec l'azote comme hétéro-atome du cycle, p. ex. amrinone
A61K 31/4709 - Quinoléines non condensées contenant d'autres hétérocycles
A61K 31/473 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes carbocycliques, p. ex. acridines, phénantridines
A61K 31/4745 - QuinoléinesIsoquinoléines condensées en ortho ou en péri avec des systèmes hétérocycliques condensées avec des systèmes cycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. phénanthrolines
A61K 31/5383 - 1,4-Oxazines, p. ex. morpholine condensées en ortho ou en péri avec des systèmes hétérocycliques
A61P 31/14 - Antiviraux pour le traitement des virus ARN
60.
ASYMMETRIC ANTIBODY WITH IMPROVED CYTOTOXICITY AGAINST CANCER CELLS
Korea University Research and Business Foundation (République de Corée)
SG MEDICAL, INC. (République de Corée)
Inventeur(s)
Jung, Sang Taek
Lee, Ji Chul
Min, Sung-Won
Bae, Gong Deuk
Kwon, Hyeong Sun
Lee, Sang Min
Abrégé
The present disclosure relates to an anti-CD20 asymmetric antibody including a single-chain variable fragment (scFv) on one side and an antigen-binding fragment (Fab) on the other side. Compared to an antibody having a symmetric structure, the asymmetric antibody of the present disclosure effectively activates complements and exhibits significantly improved complement-dependent cytotoxicity (CDC), and thus can be advantageously used as an effective therapeutic agent or therapeutic adjuvant for treating cancer.
C07K 16/28 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
61.
EXTRACTION METHOD FOR SIMULTANEOUSLY PERFORMING BIOLOGICAL MATERIAL DISRUPTION AND NUCLEIC ACID ADSORPTION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Shin, Se-Hyun
Abrégé
The present invention relates to an extraction method for simultaneously performing biological material disruption and nucleic acid adsorption and, more specifically, to an extraction method for simultaneously performing biological material disruption and nucleic acid adsorption, which rapidly lyses the membrane of a biological material included in a biological sample, and immediately extracts and separates nucleic acids released from the biological material, thereby minimizing cleavage or destruction of the nucleic acids. According to the present invention, when a suitable chamber and blade are configured so that a biological material is disrupted by a rotating blade, the membrane of the biological material is mostly disrupted within several minutes by a high-speed rotating blade, whereby a material inside a cell can be easily extracted.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Yun, Cheol Won
Abrégé
The present invention relates to an indazole-based compound having a synergistic effect on an antifungal agent and a use thereof and, more particularly, to: an antifungal adjuvant comprising, as an active ingredient, any one compound selected from the group consisting of formulae 1 to 16 or a pharmaceutically acceptable salt thereof; an antifungal combination preparation comprising the antifungal adjuvant and an Echinocandins antifungal agent as active ingredients; a pharmaceutical composition for preventing or treating fungal infections; and a method for inhibiting fungi in vitro, the method comprising a step for treating with a combination of the antifungal adjuvant of the present invention and an Echinocandins antifungal agent. When used in combination with an Echinocandins antifungal agent, the antifungal adjuvant provided in the present invention makes it possible to effectively inhibit the growth of fungi using only a small amount of the antifungal agent, and thereby induce an antibacterial synergistic effect of the antifungal agent and improve a bacteriostatic effect of the Echinocandins antifungal agent. Therefore, the antifungal adjuvant can be usefully used in the manufacture of an antibacterial composition for preventing fungal infection and a medicine for treating fungal infectious diseases.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Hong, Chang Seop
Choe, Jong Hyeak
Abrégé
The present invention relates to a novel ligand based on azine linkage, a metal-organic framework comprising same, and use thereof. The novel ligand based on azine linkage of the present invention can be usefully used as a material for preparing the metal-organic framework. In addition, the metal-organic framework comprising the novel ligand of the present invention has excellent gas adsorption ability, and thus can be usefully utilized as an adsorbent for gases including carbon dioxide.
C07C 251/88 - Hydrazones ayant également l'autre atome d'azote lié par une liaison double à un atome de carbone, p. ex. azines
C07C 251/86 - Hydrazones ayant des atomes de carbone, liés par des liaisons doubles, de groupes hydrazone liés à des atomes de carbone de cycles aromatiques à six chaînons
B01J 20/22 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtrationAbsorbants ou adsorbants pour la chromatographieProcédés pour leur préparation, régénération ou réactivation contenant une substance organique
B01D 53/02 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par adsorption, p. ex. chromatographie préparatoire en phase gazeuse
64.
PROBE FOR MEASURING CATHEPSIN K ACTIVITY AND COMPOSITION FOR DIAGNOSING BONE DISEASE COMPRISING SAME
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Park, Serkin
Kim, Jong Seung
Koo, Seyoung
Lee, Eun Jung
Abrégé
The present invention relates to a probe for measuring cathepsin K activity, a composition for measuring osteoclast activity comprising the probe, a composition for diagnosing bone diseases comprising the probe, a kit for measuring osteoclast activity comprising the composition, a kit for diagnosing bone diseases, a method for measuring cathepsin K activity, a method for measuring osteoclast activity, a method for diagnosing bone diseases, a composition for screening drugs inhibiting cathepsin K activity, and a method for screening drugs inhibiting cathepsin K activity. According to the present invention, rapidity and accuracy of diagnosis can be increased by designing a probe for measuring the activity of cathepsin K specifically expressed in osteoclasts, and thus the probe can be advantageously used for diagnosing bone diseases and screening cathepsin K activity-inhibiting drugs.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
65.
MAGNETIC STRUCTURE WITH SPIKE STRUCTURE AND METHOD FOR PREPARING THE SAME
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kang, Heemin
Min, Sunhong
Hong, Hyunshik
Kim, Seong Yeol
Kim, Kanghyeon
Kim, Chowon
Abrégé
Disclosed is a magnetic structure having a spike structure, the magnetic structure comprising: a core including at least one magnetic nanoparticle; a buffer disposed on an outer surface of the core; a shell disposed on an outer surface of the buffer, and at least one spike structure protruding outwardly from the shell, wherein the spike structure is controlled to have various shapes.
H01F 1/00 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriésEmploi de matériaux spécifiés pour leurs propriétés magnétiques
66.
MORPHOMETRICS-BASED METHOD FOR IDENTIFYING SPECIES OF FLIES BY USING POSTERIOR SPIRACLES
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kang, Tae-Mo
Park, Ji-Eun
Park, Seong Hwan
Abrégé
Calliphora lataCalliphora vicinaTriceratopyga calliphoroidesLucilia illustrisLucilia caesarLucilia sericataChrysomya megacephalaChrysomya pinguisPhormia reginaPhormia regina (re), which belong to the family Calliphoridae; statistically analyzing the significance thereof to demonstrate that high accuracy is exhibited; and identifying that the classification index of species identification has low correlation with the degree of growth (body length) of larvae.
G01N 33/483 - Analyse physique de matériau biologique
67.
COMPOSITION FOR PREVENTING, TREATING OR ALLEVIATING RHEUMATOID ARTHRITIS COMPRISING PROPIONIBACTERIUM FREUDENREICHII MJ2 STRAIN AS AN ACTIVE INGREDIENT
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lim, Young Hee
Yeom, Jiah
Ma, Seong-Ho
Yim, Dong-Joon
Abrégé
The present invention relates to a composition including a Propionibacterium freudenreichii MJ2 strain as an active ingredient for preventing, alleviating, or treating rheumatoid arthritis. The composition of the present invention is safe even when administered for a long period of time and restores autophagy to a normal level while inhibiting osteoclast differentiation, inflammatory reactions, apoptosis, and antibody production, and is thus expected to be variously used for drugs, quasi-drugs, functional foods, and the like for preventing, treating, and alleviating rheumatoid arthritis, which is an autoimmune disease.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Jee Won
Yu, Yeon Hwa
Choi, Yoo Bin
Abrégé
The present invention relates to a protein including self-assembled ferritin monomers, in which a methane oxidation active domain, and an electron transfer domain including a flavin adenine dinucleotide (FAD)-binding domain are fused, and to: a protein which can oxidize methane by using NADH in vivo as a reducing agent, thus being capable of oxidizing methane to methanol without using a separate reducing agent; a microorganism expressing the same; a composition for producing methanol by using the same; and a method for producing methanol.
C12N 9/02 - Oxydoréductases (1.), p. ex. luciférase
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
C12P 7/04 - Préparation de composés organiques contenant de l'oxygène contenant un groupe hydroxyle acycliques
69.
METHOD FOR MANUFACTURING A THIN FILM COMPOSITE MEMBRANE FOR ALKALINE WATER ELECTROLYSIS
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Jung Hyun
Jeon, Sung Kwon
Choi, Ju Yeon
Kim, Han Soo
Abrégé
The present invention relates to a method for manufacturing a thin film composite membrane for alkaline water electrolysis, and to a thin film composite membrane for alkaline water electrolysis. The present invention can provide a thin film composite membrane, which has excellent water electrolysis performance due to low mass transport resistance and high ion conductivity thereof compared to conventional nonporous membranes and porous membranes, and it is also highly safe by lowering gas permeability and minimizing gas mixing.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, In Hwan
Son, Ho Ki
Abrégé
The semiconductor substrate of the present invention may comprise a substrate and a semiconductor layer arranged on the substrate. Additional energy is supplied to sputtering in a thin film growth process step so that the semiconductor layer can be deposited. The additional energy can be at least one from among an ion beam, an electron beam, plasma, ultraviolet rays, a laser, and an LED light source. For example, the substrate can be a glass substrate, and the semiconductor layer can be a nitride semiconductor layer having a single-crystal plane. The semiconductor layer can be deposited by means of ion beam sputtering using the ion beam as the additional energy.
H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote
H01L 33/16 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure cristalline ou une orientation particulière, p.ex. polycristalline, amorphe ou poreuse
71.
ANTICANCER PHARMACEUTICAL COMPOSITION CONTAINING IF1 AS ACTIVE INGREDIENT
Korea University Research and Business Foundation (République de Corée)
CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (République de Corée)
Inventeur(s)
Shin, Min-Jeong
Kim, Hyeon Soo
Jeong, Inhyeok
Yoo, Eun Hye
Chung, Ji Hyung
Abrégé
The present invention pertains to an anticancer composition containing IF1 (ATPase inhibitory factor 1). The IF1 (ATPase inhibitory factor 1) according to the present invention has the effect of releasing extracellular ATP, induces cytotoxicity in various cancer cells and exhibits anticancer efficacy, and is thus very useful as an active ingredient of a powerful anticancer agent.
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Hong, Sung Hoi
Chol, Kyung-Ah
Abrégé
The present invention relates to a composition for inhibiting teratoma formation or growth, comprising tissue inhibitor of metalloproteinase 1 (TIMP-1) or tissue inhibitor of metalloproteinase 2 (TIMP-2) as an effective component. A pharmaceutical composition for inhibiting teratoma formation or growth comprising TIMP-1 or TIMP-2 as an effective component according to the present invention, when used in stem cell therapy, can inhibit the formation and growth of teratomas caused by undifferentiated pluripotent stem cells, without affecting the differentiation potential thereof, and thus can be advantageously used as a combination drug in combination with a stem cell drug.
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Choi, Jung-Kyu
Lee, Kwan-Young
Jeong, Yang-Hwan
Kim, Se-Jin
Abrégé
The present disclosure may provide a CHA-DDR type zeolite membrane including: a first layer including a CHA structure and a DDR structure; and a second layer which is provided on the first layer and includes a DDR structure, wherein the CHA-DDR type zeolite membrane is in the form of a film having a thickness of 100 nm to 5 μm, including a CHA structure and a DDR structure.
C01B 39/04 - Zéolites aluminosilicates cristallinesLeurs composés isomorphesLeur préparation directeLeur préparation à partir d'un mélange réactionnel contenant une zéolite cristalline d'un autre type, ou à partir de réactants préformésLeur post-traitement utilisant au moins un agent structurant organique, p. ex. un composé d'ammonium quaternaire ionique ou un composé aminé
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
Fabric-type titanium oxide-based porous water electrolysis electrode and method for manufacturing the same, and water electrolysis device comprising the same
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Cho, Jinhan
Mo, Jeongmin
Ko, Youn Ji
Choi, Wondo
Abrégé
The present invention relates to a fabric-type titanium oxide (TiOx)-based porous water electrolysis electrode, a method for preparing the same, and a water electrolysis device comprising the same.
C25B 11/053 - Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques caractérisées par des revêtements électro-catalytiques multicouches
C23C 14/20 - Matériau métallique, bore ou silicium sur des substrats organiques
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
C25B 11/056 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau du substrat ou du support constitué d'une matière textile ou non tissée
C25B 11/069 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau du substrat ou du support formé d’un élément et d’au moins un composéÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau du substrat ou du support formé de plusieurs composés
C25B 11/093 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un métal noble ou oxyde de métal noble et au moins un oxyde d’un métal non noble
C25B 11/095 - Électrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé d’au moins un élément catalytique et d’au moins un composé catalytiqueÉlectrodes comportant des électro-catalyseurs sur un substrat ou un support caractérisées par le matériau électro-catalytique formé de plusieurs éléments catalytiques ou composés catalytiques au moins un des composés est de type organique
C25B 11/097 - Plusieurs métaux nobles ou alliages de métaux nobles
C25D 3/12 - Dépôt électrochimiqueBains utilisés à partir de solutions de nickel ou de cobalt
C25D 7/00 - Dépôt électrochimique caractérisé par l'objet à revêtir
75.
COMPOSITION INCLUDING PROPIONIBACTERIUM FREUDENREICHII MJ2 STRAIN-DERIVED EXTRACELLULAR VESICLES OR CHAPERONIN PROTEIN AS ACTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RHEUMATOID ARTHRITIS
A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p. ex. arthrites, arthroses
A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Han, Chang Soo
Seo, Seung Hwan
Abrégé
The disclosed artificial tactile sensor device according to the present invention comprises: a first material unit having rigidity and elasticity; a second material unit having rigidity and elasticity equal to or different from those of the first material unit and being in close contact with the first material unit; a deformation unit disposed in a protrusion protruding from any one of the first and second material units toward the other at the interface between the first and second material units so as to be deformed by a stimulus input from any one of the first and second material units; and an electrode unit for electrically sensing deformation of the deformation unit. This structure enables the replication of the human tactile sense, thereby providing a high-performance tactile sensor capable of measuring stimulation coming from various directions such as vibration stimulation, shear stress, and the like.
G01L 1/18 - Mesure des forces ou des contraintes, en général en utilisant des propriétés des matériaux piézo-résistants, c.-à-d. des matériaux dont la résistance ohmique varie suivant les modifications de la grandeur ou de la direction de la force appliquée au matériau
G01L 5/162 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques pour la mesure de plusieurs composantes de la force en utilisant des variations de résistance ohmique de piézorésistances
77.
COMPOSITION FOR IMPROVING RENAL FUNCTION, COMPRISING MILK-DERIVED EXOSOMES AS ACTIVE INGREDIENT
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Yang, Yoosoo
Jang, Ho-Chung
Park, Daeho
Kim, Myung-Gyu
Abrégé
Disclosed in the present application is a composition for alleviating renal functional impairment, comprising, as an active ingredient, milk-derived exosomes in which nucleic acid oligomers are encapsulated. The composition comprises milk-derived exosomes in which PTP1B siRNA is encapsulated. The composition provides the effects of reducing blood urea nitrogen and/or creatinine values having increased because of renal damage and/or reducing inflammatory responses in renal cells.
A61K 31/713 - Acides nucléiques ou oligonucléotides à structure en double-hélice
A61P 13/12 - Médicaments pour le traitement des troubles du système urinaire des reins
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Ki Bong
Lee, Kwan Young
Kim, Hyun Wook
Abrégé
The present invention discloses a low-temperature nitrogen oxide adsorber based on a metal oxide-impregnated platinum/gamma-alumina catalyst and a method for preparing the same. According to the present invention, the present invention provides a method for preparing a passive nitrogen oxide adsorber for removing nitrogen oxide from a diesel engine, comprising the steps of: (a) impregnating a gamma-alumina support with an aqueous solution of the noble metal catalyst precursor and drying it repeatedly up to a preset number of times; (b) obtaining a noble metal/gamma-alumina catalyst by sintering at a predetermined temperature after step (a) is completed; (c) impregnating the noble metal/gamma-alumina catalyst with an aqueous solution of a metal oxide precursor and drying it repeatedly up to a preset number of times; and (d) preparing a passive nitrogen oxide adsorber composed of Ax-B/γ-alumina by sintering at a predetermined temperature after step (c) is completed, wherein the A is a noble metal catalyst, x is the mass percent of the noble metal catalyst, and the B is a metal.
B01J 23/89 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe du cuivre ou des métaux du groupe du fer combinés à des métaux nobles
B01D 53/94 - Épuration chimique ou biologique des gaz résiduaires des gaz d'échappement des moteurs à combustion par des procédés catalytiques
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Cho, A Ram
Choi, Won Suk
Lee, Se Young
Lee, Dong Hoon
Joo, Kyung Ho
Jeong, Yeon Seon
Yun, Gyung Eun
Abrégé
A vehicle is configured to provide a security function using an electronic key. A method includes receiving a vehicle control signal through an antenna device of the vehicle, extracting a scrambled timestamp sequence (STS) field in the vehicle control signal, dividing the extracted STS field into sub-fields, each of which has a predefined certain length, performing cross-correlation calculation of the divided sub-fields and sub-templates previously stored in storage of the vehicle, extracting times of arrival of the vehicle control signal from the results of performing the cross-correlation calculation, and determining the vehicle control signal as a normal signal when consistency of distribution locations of the times of arrival in the results of performing the cross-correlation calculation is greater than or equal to a predefined reference value and determining the vehicle control signal as an abnormal signal when the consistency is less than the predefined reference value.
B60H 1/00 - Dispositifs de chauffage, de refroidissement ou de ventilation
B60R 25/24 - Moyens pour enclencher ou arrêter le système antivol par des éléments d’identification électroniques comportant un code non mémorisé par l’utilisateur
80.
ANODE FOR LITHIUM SECONDARY BATTERY AND METHOD FOR MANUFACTURING SAME
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
INHA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Yun, Young Soo
Yang, Seung Jae
Ha, Son
Park, Ji Yong
Abrégé
Disclosed in the present invention is an anode for a lithium secondary battery, comprising: a substrate containing at least one metal selected from the group consisting of Li, Cu, Ni, and Mo; and a double-layer structured electrode protective film disposed on at least one surface of the substrate. The anode for a lithium secondary battery of the present invention comprises a double-layer structured electrode protective film with asymmetrically controlled surface energy and thus can suppress the formation of lithium dendrites, and a manufacturing method for the anode for a lithium secondary battery of the present invention can easily achieve an enlargement of lithium secondary batteries through a simple modification process.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Young Keun
Moon, Jun Hwan
Kim, Tae Soon
Abrégé
The present invention relates to molybdenum-based nanometal and a manufacturing method therefor. According to an embodiment of the present invention, molybdenum-based nanometal is formed, in a plating bath in which a porous frame is located having, located on one side thereof, a working electrode for an electrodeposition method, and, located on the opposite side of the one side, a counter electrode of the working electrode and in which a solution including a precursor, a buffering agent and an additive is used, by reducing molybdenum or by reducing molybdenum simultaneously with any one of cobalt, nickel and iron, in pores of the porous frame, on the basis of currents applied through the working electrode and the counter electrode, and then selectively removing from the porous frame, wherein specific resistance may be controlled on the basis of the buffering agent and the additive.
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Doh, Nak Ju
Kim, Joohyung
Abrégé
Disclosed are an apparatus and a method for estimating a user pose in a three-dimensional space. The apparatus includes a relative pose identification unit configured to identify estimated relative pose information between a plurality of images acquired in a chronological order in a real space; and a user pose estimating unit configured to: acquire a three-dimensional space model constructed using spatial information including at least one of inertial information, depth information, and image information about the real space; generate estimated pose candidate information based on the acquired three-dimensional space model; associate the identified estimated pose candidate information and the estimated relative pose information with each other; and estimate the user pose based on the association result.
G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
G06V 10/74 - Appariement de motifs d’image ou de vidéoMesures de proximité dans les espaces de caractéristiques
G06V 10/762 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant le regroupement, p. ex. de visages similaires sur les réseaux sociaux
84.
FLUID LEAK DETECTION SENSOR, MANUFACTURING METHOD, AND FLUID LEAK DETECTION SENSOR SYSTEM INCLUDING THE SAME
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Oh, Daniel
Chua, Bee Lee
Kim, Kyung Nam
Quan, Junxian
Shi, Xinyi
Abrégé
Provided is a fluid leak detection sensor system. The fluid leak detection sensor system includes: first and second electrodes spaced apart from each other; an absorption pad disposed between the first electrode and the second electrode to absorb a fluid; a first insulating tape disposed on the first electrode, and having a plurality of first holes; a second insulating tape disposed on the second electrode, and having a plurality of second holes; and an electronic unit control unit forming electrical contact points with the first electrode and the second electrode, wherein the electronic unit control unit includes: an alternating current signal generator; a peak detector circuit unit configured to measure a change in an impedance value between the first electrode and the second electrode according to the absorption of the fluid performed by the absorption pad; an electronic communication control unit; and a pair of pinch electrical connectors.
G01M 3/18 - Examen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des moyens de détection électrique pour tuyaux, câbles ou tubesExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des moyens de détection électrique pour raccords ou étanchéité de tuyauxExamen de l'étanchéité des structures ou ouvrages vis-à-vis d'un fluide par utilisation d'un fluide ou en faisant le vide par détection de la présence du fluide à l'emplacement de la fuite en utilisant des moyens de détection électrique pour soupapes
85.
AIR CONDITIONING DEVICE AND METHOD FOR ADSORBING CARBON DIOXIDE
SAMSUNG ELECTRONICS CO., LTD. (République de Corée)
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Lee, Minkyung
Kang, Yongtae
Kim, Kwangjoo
Koh, Youngdeog
Kim, Minjae
Kim, Seonggon
Lee, Jaewon
Abrégé
An air conditioning device configured so that, in a circulation operation state, a first air passage connecting a first intake port and a first discharge port is formed to move indoor air through the first intake port, through a carbon dioxide suction filter, and through the first discharge port to the indoor area, and, in a ventilation operation state, a second air passage connecting the first intake port and a second discharge port is formed to move indoor air from through the first intake port, through the carbon dioxide suction filter, and through the second discharge port to the outdoor area while a heater heats the carbon dioxide suction filter, and a third air passage connecting a second intake port to the first discharge port is formed to move outdoor air from the outdoor area through the second intake port, and through the first discharge port to the indoor area.
F24F 7/003 - Ventilation combinée avec le nettoyage de l'air
F24F 7/08 - Ventilation avec réseau de gaines à circulation d'air forcée, p. ex. par un ventilateur avec conduits séparés pour l'air fourni et l'air expulsé
F24F 8/158 - Traitement, p. ex. purification, de l'air fourni aux locaux de résidence ou de travail des êtres humains autrement que par chauffage, refroidissement, humidification ou séchage par séparation, p. ex. par filtrage par des moyens chimiques utilisant du charbon actif
F24F 8/90 - Nettoyage des appareils de purification
86.
PAM-4 TRANSCEIVER FOR CAPACITIVE-DRIVEN CHANNELS CAPABLE OF CANCELING CROSSTALK AND OPERATION METHOD THEREOF
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kim, Chulwoo
Kim, Seongcheol
Sim, Jincheol
Kwon, Youngwook
So, Junseob
Abrégé
Disclosed are a PAM-4 transceiver for capacitive-driven channels capable of canceling crosstalk and an operation method thereof. The PAM-4 transceiver includes a first channel that transmits and receives a PAM-4 signal generated based on a first input signal through a coupling capacitor disposed at a transmitting stage, and a second channel and a third channel disposed adjacent to the first channel, and the first channel includes a converter that receives a second input signal of the second channel and a third input signal of the third channel, and a cancellation circuit connected to the converter and that cancels a crosstalk occurring in the first channel due to the second input signal and the third input signal, and the cancellation circuit outputs a compensation signal corresponding to the crosstalk based on the second input signal and the third input signal.
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Choi, Jung-Kyu
Kim, Se-Jin
Abrégé
The present disclosure relates to a porous membrane and a method of manufacturing the same, and more particularly, to a thermally stable porous membrane capable of securing thermal stability and long-term stability of gas separation performance at high temperatures, and a manufacturing method thereof. This invention is related to a porous membrane comprising: a first Zeolitic Imidazolate Fragments (ZIFs) part formed on a surface of a porous support; and a second ZIFs part embedded in the porous support, wherein the second ZIFs part is formed in a state in which it penetrates from an interface between the first ZIFs part and the second ZIFs part to a predetermined depth.
C01B 3/50 - Séparation de l'hydrogène ou des gaz contenant de l'hydrogène à partir de mélanges gazeux, p. ex. purification
B01D 53/22 - Séparation de gaz ou de vapeursRécupération de vapeurs de solvants volatils dans les gazÉpuration chimique ou biologique des gaz résiduaires, p. ex. gaz d'échappement des moteurs à combustion, fumées, vapeurs, gaz de combustion ou aérosols par diffusion
B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétésProcédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
B01D 69/10 - Membranes sur supportSupports pour membranes
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Hong, Sunghoi
Nam-Kung, Yong
Hyun, Donghun
Abrégé
The present invention relates to: a gene editing composition comprising a guide RNA for editing mutated CAG repeat sequences of neural stem cells (ciNSCs) induced from somatic cells of a Huntington's disease patient; the edited ciNSCs; and a cell therapeutic agent for Huntington's disease, comprising same, wherein, in the edited ciNSCs, Huntington gene mutations are removed by the guide RNA of the present invention, and thus treatment for Huntington's disease and neuronal proliferation can be improved.
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiquesThérapie génique
A61K 35/30 - NerfsCerveauYeuxCellules cornéennesLiquide céphalorachidienCellules souches neuronalesCellules précurseurs neuronalesCellules glialesOligodendrocytesCellules de SchwannAstrogliesAstrocytesPlexus choroïdeTissu de moelle épinière
A61P 25/14 - Médicaments pour le traitement des troubles du système nerveux pour traiter les mouvements anormaux, p. ex. chorée, dyskinésie
89.
APPARATUS AND METHOD FOR CLASSIFYING DOMAIN NON-SPECIFIC IMAGES USING TEXT
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kim, Jin Kyu
Park, No Kyung
Abrégé
Disclosed is an apparatus for classifying domain non-specific images using text according to one embodiment of the present invention. According to the present invention, the learning process is performed not only using the images but also text information together, and thus even during training on images from only a few specific domains, it is possible to effectively classify the images from different domains with high accuracy by applying the human inference process.
G06V 10/80 - Fusion, c.-à-d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
G06F 40/284 - Analyse lexicale, p. ex. segmentation en unités ou cooccurrence
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p. ex. des objets vidéo
G06V 10/77 - Traitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source
G06V 10/774 - Génération d'ensembles de motifs de formationTraitement des caractéristiques d’images ou de vidéos dans les espaces de caractéristiquesDispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p. ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]Séparation aveugle de source méthodes de Bootstrap, p. ex. "bagging” ou “boosting”
G06V 10/776 - ValidationÉvaluation des performances
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
90.
COMPOSITION, AND SOLID ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Kang, Sung Joong
Hah, Hoe Jin
Seo, Ji Hun
Kim, Dong Wan
Seo, Ji Ae
Lee, Gwang Hee
Abrégé
The present invention relates to a composition for preparing a solid electrolyte including a polyrotaxane compound, a cross-linking agent, a lithium salt, and an organic solvent, wherein the cross-linking agent includes a compound represented by Formula 1 below and a compound represented by Formula 2, a method for preparing a solid electrolyte for a lithium secondary battery including thermal-curing the composition for preparing a solid electrolyte, a solid electrolyte for a lithium secondary battery including a thermo-cured product of the composition for preparing a solid electrolyte, and a lithium secondary battery including the solid electrolyte.
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
91.
PEPTIDE HAVING OBESITY AND MUSCLE LOSS INHIBITORY ACTIVITIES, AND USE THEREOF
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Shin, Min Jeong
Jeong, In Hyeok
Abrégé
The present invention relates to a peptide having obesity and muscle loss inhibitory activities, and a use thereof. The peptide has excellent effects on suppressing appetite, promoting energy metabolism, inhibiting fat accumulation, and promoting lipolysis, and inhibits muscle atrophy while promoting muscle synthesis, such that the peptide can be effectively used for the prevention or treatment of obesity and sarcopenia.
A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kim, Sang Sig
Cho, Kyoung Ah
Son, Jae Min
Abrégé
Disclosed is a stateful logic-in-memory using silicon diodes. More particularly, the stateful logic-in-memory according to an embodiment of the present invention includes a plurality of silicon diodes, each of the silicon diodes includes an anode region, a first channel region, a second channel region and a cathode region and is included as a memory cell.
G11C 11/36 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage électriques ou magnétiques particuliersÉléments d'emmagasinage correspondants utilisant des éléments électriques utilisant des dispositifs à semi-conducteurs utilisant des diodes, p. ex. comme éléments à seuil
H03K 19/20 - Circuits logiques, c.-à-d. ayant au moins deux entrées agissant sur une sortieCircuits d'inversion caractérisés par la fonction logique, p. ex. circuits ET, OU, NI, NON
H03K 19/21 - Circuits OU EXCLUSIF, c.-à-d. donnant un signal de sortie si un signal n'existe qu'à une seule entréeCircuits à COÏNCIDENCES, c.-à-d. ne donnant un signal de sortie que si tous les signaux d'entrée sont identiques
H10B 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
93.
3D DATA AUGMENTATION METHOD USING WEIGHTED LOCAL TRANSFORMATION AND APPARATUS THEREFOR
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Kim, Hyunwoo
Kim, Sihyeon
Park, Jin-Young
Lee, Sang Hyeok
Abrégé
The present disclosure relates to a three-dimensional (3D) data augmentation method using a weighted local transformation and an apparatus for the same. More specifically, the present disclosure relates to a method and apparatus of significantly augmenting 3D data required to improve the performance of an artificial intelligence model with only limited 3D data by applying a non-rigid transformation to local part(s) of the 3D data.
Korea University Research And Business Foundation (République de Corée)
Inventeur(s)
Lee, Daeho
Woo, Han Young
Ryu, Hwasook
Yoon, Seokgyu
Jung, Hyejin
Park, Chaeyeon
Jonnadula, Venkata Suman Krishna
Jee, Min Hun
Abrégé
A condensed cyclic compound represented by Formula 1, an organic photodetector including the condensed cyclic compound. and an electronic apparatus including the organic photodetector are provided:
A condensed cyclic compound represented by Formula 1, an organic photodetector including the condensed cyclic compound. and an electronic apparatus including the organic photodetector are provided:
H10K 30/40 - Dispositifs organiques sensibles au rayonnement infrarouge, à la lumière, au rayonnement électromagnétique de plus courte longueur d'onde ou au rayonnement corpusculaire comprenant une structure p-i-n, ayant p. ex. un absorbeur pérovskite entre des couches de transport de charge de type p et de type n
95.
COSMETIC COMPOSITION CONTAINING ZN-PORPHYRIN AND LIGNIN FOR BLOCKING ULTRAVIOLET RAYS
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Han, Sung Ok
Ko, Young Jin
Abrégé
The present invention relates to a cosmetic composition containing Zn-porphyrin and lignin for blocking ultraviolet rays. The cosmetic composition for blocking ultraviolet rays, according to the present invention, can effectively block UV-A and UV-B, which are harmful to the human body and, compared to when Zn-porphyrin or lignin alone is used, has significantly increased ultraviolet blocking efficiency.
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 8/72 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques macromoléculaires
A61Q 17/04 - Préparations topiques pour faire écran au soleil ou aux radiationsPréparations topiques pour bronzer
96.
HYBRID WATER TREATMENT SYSTEM FOR RED TIDE REMOVAL AND PERCHLORATE CONTROL AND WATER TREATMENT METHOD USING THE SAME
Korea University Research and Business Foundation (République de Corée)
Inventeur(s)
Hong, Seungkwan
Shin, Yong-Uk
Lim, Jihun
Abrégé
Disclosed is a hybrid water-treating system. The system includes a raw-water supply bath having a predetermined volume and configured to receive raw-water containing high concentration organic contaminants; at least one electrolytic bath configured to receive the raw-water supplied from the raw-water supply bath and to produce first treated water, wherein a boron doped diamond (BDD) electrode is installed in the electrolytic bath; and at least one deionization bath configured to receive the first treated water discharged from the electrolytic bath and to produce second treated water, wherein flow-electrode capacitive deionization (FCDI) is performed when applying a first voltage to the deionization bath.
C02F 1/467 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par électrolyse par désinfection électrochimique
C02F 1/469 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par des procédés électrochimiques par séparation électrochimique, p. ex. par électro-osmose, électrodialyse, électrophorèse
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Ahn, Chi Bum
Hwang, In Tae
Abrégé
The present invention relates to an AR-based orthodontic assistance system. The system may comprise: an imaging device for acquiring a 3D image of the teeth of a patient by using three-dimensional digital photography; a database unit for storing a target teeth model in which a target teeth arrangement generated on the basis of the 3D image of the teeth is imaged; AR glasses having a camera, which photographs the teeth of the patient so as to acquire a 2D image of the teeth, and a display, which displays a virtual image showing the teeth of the patient to be superimposed on the real world; a matching unit for generating the virtual image by matching the target teeth model and the 2D image; a marker-mounted module which is fitted into both nostrils of the patient for the matching and on which a plurality of markers are mounted; and a stereo camera for photographing the plurality of markers in order to generate reference coordinates for the matching.
A61C 7/00 - Orthodontie, c.-à-d. obtention ou maintien de la position désirée des dents, p. ex. par redressage, nivellement, ajustement, séparation, ou par correction des malocclusions
A61C 9/00 - Méthodes de prise d'empreintes spécialement conçues pour les prothèses dentairesPorte-empreintes à cet effet
A61C 19/04 - Instruments de mesure spécialement adaptés à la technique dentaire
A61C 13/00 - Prothèses dentairesLeurs procédés de fabrication
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
H04N 7/18 - Systèmes de télévision en circuit fermé [CCTV], c.-à-d. systèmes dans lesquels le signal vidéo n'est pas diffusé
G06T 1/00 - Traitement de données d'image, d'application générale
G06T 17/00 - Modélisation tridimensionnelle [3D] pour infographie
G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
G16H 30/00 - TIC spécialement adaptées au maniement ou au traitement d’images médicales
98.
SINGLE FUSION PROTEIN AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Shin, Min Jeong
Jeong, In Hyeok
Lee, Se Hee
Abrégé
The present invention relates to: a fusion protein comprising an IF1 protein and a derived peptide and an Fc region of an immunoglobulin; and a pharmaceutical composition comprising same. The fusion protein according to the present invention exhibits improved pharmacological efficacy, in vivo persistence and protein stability, and a pharmaceutical composition comprising the fusion protein as an active ingredient can be effectively used as a therapeutic agent for cancer, neurological diseases, diabetes, obesity disease, dyslipidemia, metabolic diseases, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, hair loss prevention or hair growth promotion, sarcopenia, and obese sarcopenia.
C07K 14/47 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères
A61K 38/00 - Préparations médicinales contenant des peptides
99.
BREAST CANCER-RELATED INFORMATION PROVIDING METHOD USING MAGNETIC RESONANCE IMAGE AND RNA GENETIC INFORMATION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Seo, Bo Kyoung
Park, Ah Young
Han, Mi-Ryung
Abrégé
The present invention relates to a method for providing information relating to progression or prognosis of a breast cancer and information for selecting a breast cancer treatment method, the method using a breast cancer MRI. Since genetic information can be predicted by means of a non-invasive MRI when using the method of the present invention, the method may be used to provide information relating to progression or prognosis of a breast cancer or information for selecting a breast cancer treatment method.
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (République de Corée)
Inventeur(s)
Jung, Sang-Taek
Lee, Won-Ju
Jo, Mi-Gyeong
Kyung, Mun-Su
Abrégé
The present invention relates to a glycosylated Fc variant with improved selective binding affinity to FcγRIIIa. Compared to conventional antibodies approved as antibody therapeutic agents, novel human antibody Fc domain variants of the present invention have reduced binding affinity to FcγRIIb, which is an immuno-inhibitory receptor, have improved binding affinity to FcγRIIIa (an increase in the A/I ratio), which is an immuno-activating receptor, thereby having a remarkably improved ability to induce ADCC, and have the effect of maximizing the immune action mechanism of therapeutic protein drugs, and thus can be effectively used in antibody drugs.